1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone supplier

Name
1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone
EINECS 230-625-6
CAS No. 7226-23-5
Article Data21
CAS DataBase
Density 1.024 g/cm³
Solubility Soluble in water and most organic solvents
Melting Point -20 °C
Formula C₆H₁₂N₂O
Boiling Point 240.2 °C at 760 mmHg
Molecular Weight 128.174
Flash Point 85.3 °C
Transport Information
Appearance clear colorless to slightly yellowish liquid
Safety 23-26-36/37/39-45
Risk Codes 22-36-43-62-41
Molecular Structure
Hazard Symbols Xn
Synonyms 1,3-Dimethyl-2-oxohexahydropyrimidine;1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidone;1,3-Dimethyl-3,4,5,6-tetrahydro-2-pyrimidinone;1,3-Dimethylpropyleneurea;DMPU (solvent);N,N'-Dimethyl-1,3-propanediamine cyclic urea;N,N'-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone;N,N'-Dimethyl-N,N'-propyleneurea;N,N'-Dimethyltrimethyleneurea;
PSA 23.55000
LogP 0.24950

Synthetic route

: 201230-82-2
carbon monoxide

: 111-33-1
1,3-bis(methylamino)propane

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

Conditions

Conditions	Yield
Stage #1: carbon monoxide; 1,3-bis(methylamino)propane With selenium at 20℃; under 750.075 Torr; for 2h; neat (no solvent); Stage #2: With oxygen at 20℃; under 750.075 Torr; for 1h; neat (no solvent);	94%
With iodine; potassium carbonate; tungsten hexacarbonyl In dichloromethane at 20℃; under 76005.1 Torr;	52%

: 53527-07-4
β-(4-hydroxyphenyl)ethyl iodoacetamide

: 3-(((3-acetamido-4-methoxy-2-methyl-4-oxobutan-2-yl)disulfanecarbonyl)(methyl)amino)-N-methylpropan-1-aminium trifluoroacetate

A: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

B: 55710-99-1
β-(4-hydroxyphenyl)ethyl-2-aminoacetamide

C: methyl 2-acetamido-3-((2-((4-hydroxyphenethyl)amino)-2-oxoethyl)disulfaneyl)-3-methylbutanoate

D: C18H26N2O5S

Conditions

Conditions	Yield
With diethylenetriaminopentaacetic acid In aq. buffer at 37℃; for 7h; pH=7.4; Kinetics; Solvent; pH-value;	A n/a B n/a C 90% D n/a

...Expand

: 2055-46-1
3,4,5,6-tetrahydropyrimidine-2-thione

: 74-88-4
methyl iodide

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

Conditions

Conditions	Yield
With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride for 5h; Heating;	81%
With 18-crown-6 ether; N-benzyl-N,N,N-triethylammonium chloride for 2h; Heating;	81%

: 1852-17-1
3,4,5,6-tetrahydropyrimidin-2(1H)-one

: 77-78-1
dimethyl sulfate

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

Conditions

Conditions	Yield
With N-benzyl-N,N,N-triethylammonium chloride; potassium carbonate In 1,4-dioxane at 60℃; for 5h;	78.8%

: 2,2'-oxy-bis(1,3-dimethyl-tetrahydropyrimidinium) bis(trifluoromethanesulfonate)

: 109-77-3
malononitrile

A: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

B: 55727-22-5
(1,3-dimethyl-tetrahydro-pyrimidin-2-ylidene)-malononitrile

Conditions

Conditions	Yield
With dimethylaminomethyl-polystyrene In acetonitrile at 81℃; for 8.5h;	A n/a B 78%

...Expand

: 124-38-9
carbon dioxide

: 142-28-9
1,3-Dichloropropane

: 74-89-5
methylamine

A: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

B: 96690-06-1
3-methyl-1,3-oxazinan-2-one

Conditions

Conditions	Yield
In water at 120℃; under 3750.38 Torr; for 2h;	A 64% B 15%

...Expand

: 123183-72-2
N-(tert-butyl)oxycarbonyl-N,N’-trimethyl-1,3-diaminopropane

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: N,N-dimethyl-formamide / 5 h / 0 - 20 °C 2: dichloromethane / 1 h / 20 °C / Inert atmosphere 3: 37 °C / pH 5.5 View Scheme
Multi-step reaction with 3 steps 1: triethylamine / N,N-dimethyl-formamide / 1 h / 0 - 20 °C / Inert atmosphere 2: dichloromethane / 1 h / 20 °C / Inert atmosphere 3: 37 °C / pH 5.5 View Scheme

: 111-33-1
1,3-bis(methylamino)propane

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: tetrahydrofuran / 22 h / 0 - 20 °C / Inert atmosphere 2: N,N-dimethyl-formamide / 5 h / 0 - 20 °C 3: dichloromethane / 1 h / 20 °C / Inert atmosphere 4: 37 °C / pH 5.5 View Scheme
Multi-step reaction with 4 steps 1: tetrahydrofuran / 22 h / 0 - 20 °C / Inert atmosphere 2: triethylamine / N,N-dimethyl-formamide / 1 h / 0 - 20 °C / Inert atmosphere 3: dichloromethane / 1 h / 20 °C / Inert atmosphere 4: 37 °C / pH 5.5 View Scheme

: C28H32N4O6*C2HF3O2

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

Conditions

Conditions	Yield
at 37℃; pH=5.5;

: C26H28N4O5*C2HF3O2

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

Conditions

Conditions	Yield
at 37℃; pH=5.5;

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 73183-34-3
bis(pinacol)diborane

: 1391930-67-8
1-methyl-3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)tetrahydropyrimidin-2(1H)-one

Conditions

Conditions	Yield
With C25H36O2P2Ru In neat (no solvent) at 120℃; for 24h; Catalytic behavior; Green chemistry;	98%
With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 8-(diisopropylsilyl)quinoline In 1,4-dioxane at 120℃; for 20h; Inert atmosphere; Sealed tube;	96%
With methoxy(cyclooctadiene)rhodium(I) dimer In hexane at 40℃; for 1h; Inert atmosphere; Sealed tube;	75%

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 94138-28-0
samarium diiodide bis(tetrahydrofuran)

: [Sm(dimethylpropyleneurea)6]I2

Conditions

Conditions	Yield
In tetrahydrofuran 6-fold excess of ligand added to soln. of Sm complex in THF at room temp. under Ar; left to stand for 2 h; evapd., washed with toluene; elem. anal.; X-ray detn.;	97%

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 73183-34-3
bis(pinacol)diborane

A: 1391930-67-8
1-methyl-3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)tetrahydropyrimidin-2(1H)-one

B: C3H6N(CH3)CONCH(BO2C2(CH3)4)2

Conditions

Conditions	Yield
With methoxy(cyclooctadiene)rhodium(I) dimer In hexane at 25℃; for 1h; Inert atmosphere; regioselective reaction;	A 97% B 7%
With catalyst:[Rh(OCH3)(C8H12)]2 and silicaphosphine In hexane diboron, amide, catalyst:(Rh(OCH3)(C8H12))2, silica-supported triarylphosphine, hexane, 25°C, 1 h or 70°C 3 h;	A 85% B 2%

...Expand

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 14965-49-2
methylamine hydroiodide

: lead(II) iodide

: CH6N(1+)*Pb(2+)*3I(1-)*2C6H12N2O

Conditions

Conditions	Yield
at 80℃; for 0.5h;	96%

...Expand

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 354-64-3
Pentafluoroethyl iodide

: 557-20-0
diethylzinc

: Zn(C2F5)2(1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone)2

Conditions

Conditions	Yield
In hexane; toluene at -35 - -5℃; for 24h; Inert atmosphere;	95%
In hexane at -60 - 0℃; for 48h; Inert atmosphere;	86%

...Expand

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 754-34-7
1,1,1,2,2,3,3-heptafluoro-3-iodo-propane

: 557-20-0
diethylzinc

: Zn(nC3F7)2(1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone)2

Conditions

Conditions	Yield
In hexane at -60 - -20℃; for 48h; Inert atmosphere;	95%
In hexane; toluene at -35 - -5℃; for 24h; Inert atmosphere;	93%
In hexane; toluene at -41 - -5℃; for 12h; Inert atmosphere;	92%

...Expand

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 354-64-3
Pentafluoroethyl iodide

: 557-20-0
diethylzinc

: C4F10Zn*2C6H12N2O

Conditions

Conditions	Yield
In hexane; toluene at -35 - -5℃; for 24h; Inert atmosphere;	95%

...Expand

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 1493-03-4
iododifluoromethane

: 557-20-0
diethylzinc

: (1,3-dimethyl-3,4,5,6-tetrahydro-2-pyrimidinone)2Zn(CF2H)2

Conditions

Conditions	Yield
In hexane; pentane at -20 - 20℃; Inert atmosphere; Glovebox;	94%

...Expand

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 754-34-7
1,1,1,2,2,3,3-heptafluoro-3-iodo-propane

: 557-20-0
diethylzinc

: C6F14Zn*2C6H12N2O

Conditions

Conditions	Yield
In hexane; toluene at -35 - -5℃; for 24h; Inert atmosphere;	93%

...Expand

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 172747-89-6
triphenyltin dimesylamide

: triphenyltin(IV)-dimesylamide-N,N'-dimethylpropyleneurea (1/1)

Conditions

Conditions	Yield
In acetonitrile N2 atm.; equimolar ratio, stirring (20°C), refluxing (2 h); evapn., addn. of Et2O, digestion, filtn., washing (Et2O), drying (vac.);elem. anal.;	92%

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 375-80-4
dodecafluoro-1,6-diiodohexane

: 557-20-0
diethylzinc

: [(1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone)2Zn((CF2)6)2Zn(1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone)2]

Conditions

Conditions	Yield
Stage #1: dodecafluoro-1,6-diiodohexane; diethylzinc In hexane; pentane at -78 - 20℃; Inert atmosphere; Glovebox; Stage #2: 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone In hexane; pentane at 20℃; Inert atmosphere; Glovebox;	92%

...Expand

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 1493-03-4
iododifluoromethane

: 557-20-0
diethylzinc

: [bis(difluoromethyl)zinc(dmpu)2]

Conditions

Conditions	Yield
In hexane Inert atmosphere;	92%
In hexane; pentane at -20 - 20℃; for 2h;	89%
In hexane; pentane at -20 - 20℃; for 2h;	89%

...Expand

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 136-95-8
2-amino-benzthiazole

: 144467-83-4
Benzothiazol-2-ylamine; compound with 1,3-dimethyl-tetrahydro-pyrimidin-2-one

Conditions

Conditions	Yield
In toluene at 0℃; for 24h;	91%

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 94348-89-7
{(η5-C5Me5)2YCl}2

: 431887-85-3
(C5(CH3)5)2YCl((CH2)3(NCH3)2CO)

Conditions

Conditions	Yield
In benzene (N2); addn. of a soln. of ligand in benzene to a slurry of yttrium complex in benzene, stirring for 1 h; evapn.; elem. anal.;	90%

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 2314-97-8
iodotrifluoromethane

: 557-20-0
diethylzinc

: (1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone)2Zn(CF3)2

Conditions

Conditions	Yield
In hexane at -60 - -20℃; for 48h; Inert atmosphere;	90%

...Expand

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 2314-97-8
iodotrifluoromethane

: 557-20-0
diethylzinc

: (CF3)2Zn(DMPU)2

Conditions

Conditions	Yield
In hexane at -60 - -20℃; for 72h; Inert atmosphere;	90%

...Expand

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 2314-97-8
iodotrifluoromethane

: 557-20-0
diethylzinc

: C6H12N2O*C2F6Zn

Conditions

Conditions	Yield
In hexane at -60 - -20℃; for 72h; Inert atmosphere;	90%

...Expand

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 86-74-8
9H-carbazole

: 2236-52-4
2,2'-diiodobiphenyl

: 207447-27-6
9-(4'-iodine-[1,1'-biphenyl]-4-yl)-9H-carbazole

Conditions

Conditions	Yield
With potassium carbonate; 18-crown-6 ether; copper(I) iodide In hexane; water; toluene	89%

...Expand

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 423-39-2
1-iodo-2,2,3,3,4,4,5,5,5-nonafluorobutane

: 557-20-0
diethylzinc

: C8F18Zn*2C6H12N2O

Conditions

Conditions	Yield
In toluene at -35 - -5℃; for 24h; Inert atmosphere;	89%

...Expand

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 423-39-2
1-iodo-2,2,3,3,4,4,5,5,5-nonafluorobutane

: 557-20-0
diethylzinc

: Zn(C4F9)2(DMPU)2

Conditions

Conditions	Yield
In hexane; toluene at -35 - -5℃; for 24h; Inert atmosphere;	89%
In hexane at -35 - -5℃; for 24h; Inert atmosphere;	89%
In hexane; toluene at -41 - -5℃; for 12h; Inert atmosphere;	88%

...Expand

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 355-43-1
n-perfluorohexyl iodide

: 557-20-0
diethylzinc

: Zn(nC6F13)2(1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone)2

Conditions

Conditions	Yield
In hexane at -60 - 0℃; for 48h; Inert atmosphere;	88%
In hexane; toluene at -35 - -5℃; for 24h; Inert atmosphere;	88%
In hexane; toluene at -41 - -5℃; for 12h; Inert atmosphere;	87%

...Expand

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 355-43-1
n-perfluorohexyl iodide

: 557-20-0
diethylzinc

: C12F26Zn*2C6H12N2O

Conditions

Conditions	Yield
In hexane; toluene at -35 - -5℃; for 24h; Inert atmosphere;	88%

...Expand

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 3056-17-5
stavudin

: 938050-90-9
2',3'-didehydro-3'-deoxythymidine N,N-dimethyl propylene urea solvate

Conditions

Conditions	Yield
In acetone at 56℃; for 0.25 - 0.5h; Product distribution / selectivity; Heating / reflux;	87.5%
In acetone at 6 - 56℃; for 0.25h; Product distribution / selectivity;	87.5%
In isopropyl alcohol at 70 - 75℃; for 0.25h; Product distribution / selectivity;	86.7%

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 172747-89-6
triphenyltin dimesylamide

: triphenyltin(IV)-dimesylamide-N,N'-dimethylpropyleneurea (1/2)

Conditions

Conditions	Yield
In acetonitrile N2 atm.; 2 equiv. of ligand, stirring (20°C), refluxing (2 h); evapn., addn. of Et2O, digestion, filtn., washing (Et2O), drying (vac.);elem. anal.;	87%

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: 1356922-21-8
3-(3-bromophenyl)-1,2,4-triazolo[3,4-a]isoquinoline

: 86-74-8
9H-carbazole

: 1356922-22-9
3-[3-(9H-carbazol-9-yl)phenyl]-1,2,4-triazolo[3,4-a]isoquinoline

Conditions

Conditions	Yield
With sodium bicarbonate; potassium carbonate; copper(I) iodide; 18-crown-6 ether In chloroform	86%

...Expand

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: samarium(III) trifluoromethanesulfonate

: [Sm(1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidone)6](O3SCF3)3

Conditions

Conditions	Yield
In tetrahydrofuran Ar-atmosphere; addn. of 6 equiv. ligand to metal salt, standing for 1 h; solvent removal (reduced pressure);	85%

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: formamidinium iodide

: lead(II) iodide

: CH5N2(1+)*Pb(2+)*3I(1-)*2C6H12N2O

Conditions

Conditions	Yield
at 90℃; for 0.5h;	85%

...Expand

: 4076-36-2
5-methyl-1,2,3,4-tetrazole

: 7226-23-5
1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

: zinc(II) nitrate hexahydrate

: 64-17-5
ethanol

: Zn(5-methyltetrazole(-H))2·0.5(tetrahydro-1,3-dimethyl-2(1H) pyrimidine)·0.5(ethanol)

Conditions

Conditions	Yield
at 120℃; for 72h; Sealed tube;	84%

...Expand

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone Specification

The IUPAC name of Dimethylpropyleneurea is 1,3-dimethyl-1,3-diazinan-2-one. With the CAS registry number 7226-23-5 and EINECS 230-625-6, it is also named as 2(1H)-Pyrimidinone, tetrahydro-1,3-dimethyl-. The classification codes are Drug / Therapeutic Agent; TSCA Flag P [A commenced PMN (Premanufacture Notice) substance]. It is clear colorless to slightly yellowish liquid which is soluble in water and most organic solvents. Additionally, this chemical should be sealed in the container and stored in the cool and dry place.

The other characteristics of this product can be summarized as: (1)ACD/LogP: 0.36; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.36; (4)ACD/LogD (pH 7.4): 0.36; (5)ACD/BCF (pH 5.5): 1.11; (6)ACD/BCF (pH 7.4): 1.11; (7)ACD/KOC (pH 5.5): 37.53; (8)ACD/KOC (pH 7.4): 37.53; (9)#H bond acceptors: 3; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 23.55 Å²; (13)Index of Refraction: 1.473; (14)Molar Refractivity: 35.12 cm³; (15)Molar Volume: 125 cm³; (16)Polarizability: 13.92×10^-24 cm³; (17)Surface Tension: 32.4 dyne/cm; (18)Density: 1.024 g/cm³; (19)Flash Point: 85.3 °C; (20)Enthalpy of Vaporization: 47.71 kJ/mol; (21)Boiling Point: 240.2 °C at 760 mmHg; (22)Vapour Pressure: 0.0386 mmHg at 25°C.

Preparation of Dimethylpropyleneurea: It can be obtained by tetrahydro-pyrimidin-2-one and sulfuric acid dimethyl ester. This reaction needs reagents K₂CO₃, TEBA and solvent dioxane at temperature of 60 °C. The reaction time is 5 hours. The yield is 78.8%.

Dimethylpropyleneurea can be obtained by tetrahydro-pyrimidin-2-one and sulfuric acid dimethyl ester

Uses of Dimethylpropyleneurea: It is a cyclic urea sometimes used as a polar, aprotic organic solvent. And it can react with trifluoro-methanesulfonic acid anhydride to get 2,2'-oxy-bis(1,3-dimethyl-tetrahydropyrimidinium) bis(trifluoromethanesulfonate). This reaction needs solvent CH₂Cl₂ by heating. The reaction time is 48 hours. The yield is 50%.

Dimethylpropyleneurea can react with trifluoro-methanesulfonic acid anhydride to get 2,2'-oxy-bis(1,3-dimethyl-tetrahydropyrimidinium) bis(trifluoromethanesulfonate)

When you are using this chemical, please be cautious about it as the following:
It is not only harmful if swallowed, but also irritating to eyes. And it may cause sensitization by skin contact. So people should not breathe vapour. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

People can use the following data to convert to the molecule structure.
1. SMILES:O=C1N(C)CCCN1C
2. InChI:InChI=1/C6H12N2O/c1-7-4-3-5-8(2)6(7)9/h3-5H2,1-2H3
3. InChIKey:GUVUOGQBMYCBQP-UHFFFAOYAB

The following are the toxicity data which has been tested.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	1300mg/kg (1300mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Journal of Medicinal Chemistry. Vol. 11, Pg. 214, 1968.

Product Name

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone

Synthetic route

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone Specification

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