1-Chloropropane supplier | CasNO.540-54-5

Name
n-Propyl chloride
EINECS 208-749-7
CAS No. 540-54-5
Article Data147
CAS DataBase
Density 0.878 g/cm³
Solubility 2.7 g/L (20 °C ) in water
Melting Point -123 °C
Formula C₃H₇Cl
Boiling Point 46.8 °C at 760 mmHg
Molecular Weight 78.5416
Flash Point ?25°F
Transport Information UN 1278 3/PG 2
Appearance Clear colourless liquid
Safety 9-29
Risk Codes 11-20/21/22
Molecular Structure
Hazard Symbols F，Xn
Synonyms 1-Chloropropane;Propyl chloride;n-Propyl chloride;
PSA 0.00000
LogP 1.63520

Synthetic route

: 18955-01-6, 104759-03-7, 24162-13-8
tris-2,2'-bipyridyl ruthenium(III) ion

: 111323-58-1
H2O(1,4,8,11-tetraazacyclotetradecane)CoPr(2+)

: 540-54-5
1-Chloropropane

Conditions

Conditions	Yield
With chloropentamminecobalt(III)(2+) Kinetics; reaction of Ru(bpy)3(3+) with excess Co-compound in presence of Co(NH3)5Cl(2+);;	100%

: 84298-20-4
propyl 2-chloro-1,1-diethyl carbamate

A: 540-54-5
1-Chloropropane

B: 84298-23-7
4,4-di-2-oxazolidone

Conditions

Conditions	Yield
at 150℃; for 1h;	A n/a B 98%

: 143885-02-3
propyloxy(diphenyl)-λ6-sulfanenitrile

A: 540-54-5
1-Chloropropane

B: 22731-83-5
S,S-diphenylsulphoximine

Conditions

Conditions	Yield
With hydrogenchloride In [D3]acetonitrile at 20℃; for 0.5h;	A 98% B n/a

: 56-23-5
tetrachloromethane

: 628-85-3
di-n-propylmercury

A: mercury(I) chloride

B: 540-54-5
1-Chloropropane

C: 67-66-3
chloroform

D: 2440-40-6
n-propylmercury(II) chloride

E: mercury

Conditions

Conditions	Yield
In neat (no solvent) 150°C, 60 h; further products;	A <1 B 96% C >99 D 5% E 95%

...Expand

: 71-23-8
propan-1-ol

A: 540-54-5
1-Chloropropane

B: 111-43-3
Dipropyl ether

Conditions

Conditions	Yield
With hydrogenchloride; tetrabutylphosphonium ion; silica gel at 170℃; under 760 Torr;	A 94% B 5 % Chromat.

: 71-23-8
propan-1-ol

: 540-54-5
1-Chloropropane

Conditions

Conditions	Yield
With chloro-trimethyl-silane; dimethyl sulfoxide for 0.166667h;	93%
With priphenylchlorophosphonium phosphorodichloridate at 20℃; Arbuzov reaction;	88%
With allyltriphenoxyphosphonium chloride at 20℃;	60%

: 869-56-7
tripropyl phosphorotrithioite

A: 1642-48-4
tripropyl tetrathiophosphate

B: 540-54-5
1-Chloropropane

C: 36696-24-9
propyl phosphorodichloridothioite

D: 4104-04-5
dipropyl phosphorochloridodithioite

Conditions

Conditions	Yield
With chlorine for 0.333333h; Product distribution;	A 93% B 64% C 0.9 g D 45%

...Expand

: 71-23-8
propan-1-ol

A: 540-54-5
1-Chloropropane

B: 1809-21-8
di-n-propyl phosphonate

Conditions

Conditions	Yield
With phosphorus trichloride at 0 - 50℃; for 50h;	A n/a B 93%

: 102-69-2
tri-n-propylamine

: 540-54-5
1-Chloropropane

Conditions

Conditions	Yield
With 2-chloro-4,6-dimethoxy-1 ,3,5-triazine In toluene Reflux;	90%

: 869-56-7
tripropyl phosphorotrithioite

A: 1642-48-4
tripropyl tetrathiophosphate

B: 540-54-5
1-Chloropropane

C: 36696-24-9
propyl phosphorodichloridothioite

Conditions

Conditions	Yield
With phosphorus pentachloride at 80℃; for 0.75h; Product distribution;	A 84% B 73% C 35%

...Expand

: 143466-92-6
1,1,2,2,3,3,4,4-Octafluoro-5,5-bis-propylsulfanyl-pentane

A: 540-54-5
1-Chloropropane

B: 141700-49-4
1,1-Dichloro-2,2,3,3,4,4,5,5-octafluoro-1-propylsulfanyl-pentane

Conditions

Conditions	Yield
With chlorine In tetrachloromethane at 10℃; for 3h;	A n/a B 80%

: 923-99-9
tri-n-propyl phosphite

: 57182-16-8
2,2,2-trichloro-N-methylacetimidoyl chloride

A: 540-54-5
1-Chloropropane

B: 70795-53-8
C15H31Cl2NO6P2

Conditions

Conditions	Yield
In toluene for 2h; Heating;	A n/a B 75%

...Expand

: 923-99-9
tri-n-propyl phosphite

: 57182-25-9
N-ethyl-2,2,2-trichloro-acetimidoyl chloride

A: 540-54-5
1-Chloropropane

B: 70795-57-2
{2,2-Dichloro-1-[(dipropoxy-phosphoryl)-ethyl-amino]-vinyl}-phosphonic acid dipropyl ester

Conditions

Conditions	Yield
In toluene for 2h; Heating;	A n/a B 71%

...Expand

: 3201-75-0
Vinyliden-methylphosphonsaeure-dipropylester

: 2007-97-8
trichloro(o-phenylenedioxy)phosphorane

A: 1499-17-8
o-phenylene chlorophosphate

B: 540-54-5
1-Chloropropane

C: 21310-10-1
propyl propadienylchlorophosphonate

Conditions

Conditions	Yield
at 20℃; for 24h;	A n/a B n/a C 66%

...Expand

: 2142-68-9
1-(2-chlorophenyl)ethanone

: 1131453-88-7
C11H14ClN

A: 540-54-5
1-Chloropropane

B: 1131453-82-1
2-(2'-chlorophenyl)-4-methylquinoline

Conditions

Conditions	Yield
In toluene at 150℃; for 48h;	A n/a B 64%

...Expand

: 82718-93-2
(3,4-dihydro-2H-pyran-5-yl)phosphonous dichloride

: 71-36-3
butan-1-ol

A: 540-54-5
1-Chloropropane

B: butyl hydrogen (5,6-dihydro-4H-pyran-3-yl)phosphonite

Conditions

Conditions	Yield
In diethyl ether Ambient temperature;	A n/a B 61.3%

...Expand

: 71-23-8
propan-1-ol

: 82718-93-2
(3,4-dihydro-2H-pyran-5-yl)phosphonous dichloride

A: 540-54-5
1-Chloropropane

B: propyl hydrogen (5,6-dihydro-4H-pyran-3-yl)phosphonite

Conditions

Conditions	Yield
In diethyl ether Ambient temperature;	A n/a B 60.2%

...Expand

: 56-23-5
tetrachloromethane

: 80937-33-3
oxygen

: 628-85-3
di-n-propylmercury

A: mercury(I) chloride

B: 540-54-5
1-Chloropropane

C: 67-66-3
chloroform

D: 2440-40-6
n-propylmercury(II) chloride

E: mercury

Conditions

Conditions	Yield
In neat (no solvent) 100°C, 60 h; further products;	A 5% B 58% C 39% D 50% E 40%

...Expand

: 71-23-8
propan-1-ol

: 66517-43-9
(4,5-dihydro-3-furyl)phosphonous dichloride

A: 540-54-5
1-Chloropropane

B: propyl hydrogen (4,5-dihydro-3-furyl)phosphonite

Conditions

Conditions	Yield
With triethylamine In diethyl ether at -20 - -15℃; for 0.333333h;	A n/a B 54.4%

...Expand

: 19432-96-3
3-(phenylsulfonyl)propyl chloride

A: 540-54-5
1-Chloropropane

B: 17637-57-9
(cyclopropylsulfonyl)benzene

C: 2163-00-0
1,6-dichlorohexane

Conditions

Conditions	Yield
With sodium amalgam In benzene for 6h; Heating;	A 17% B 53% C 13%

...Expand

: 71-23-8
propan-1-ol

: 66441-49-4
<2-(2-chloroethoxy)vinyl>phosphonous dichloride

A: 540-54-5
1-Chloropropane

B: propyl hydrogen <2-(2-chloroethoxy)vinyl>phosphonite

Conditions

Conditions	Yield
With triethylamine In diethyl ether at -20 - -15℃; for 0.333333h;	A n/a B 40%

...Expand

: 27976-44-9
bis-(4-methoxyphenyltelluro)methane

: C6H6Cl2Pd2

A: 104-93-8
4-Methylanisole

B: 540-54-5
1-Chloropropane

C: 2132-80-1
4,4'-Dimethoxybiphenyl

D: 4456-34-2
bis(4-methoxyphenyl)telluride

: [PdCl(μ-TeC6H4-OCH3)Te(C6H4-OCH3)2]2

: Pd20Te7

G: 150-76-5
4-methoxy-phenol

Conditions

Conditions	Yield
In dichloromethane at 20℃; Mechanism;	A n/a B n/a C n/a D n/a E 4% F 10% G n/a

...Expand

: 110-86-1
pyridine

: 2812-74-0
(Propoxy)thiocarbonylchlorid

A: 463-58-1
carbon oxide sulfide

B: 540-54-5
1-Chloropropane

...Expand

: 91-22-5
quinoline

: 2812-74-0
(Propoxy)thiocarbonylchlorid

A: 463-58-1
carbon oxide sulfide

B: 540-54-5
1-Chloropropane

Conditions

Conditions	Yield
at 29℃;

...Expand

: 71-23-8
propan-1-ol

A: 540-54-5
1-Chloropropane

B: 75-29-6
isopropyl chloride

Conditions

Conditions	Yield
With hydrogenchloride; aluminum oxide at 420℃;

: 56-23-5
tetrachloromethane

: 2143-61-5
n-Propyl-Radikal

: 540-54-5
1-Chloropropane

Conditions

Conditions	Yield
sowie Isomerisierung bei Siedetemperatur;

: 56-23-5
tetrachloromethane

: 2697-95-2
dibutyryl peroxide

A: 540-54-5
1-Chloropropane

B: 67-72-1
hexachloroethane

...Expand

: 187737-37-7
propene

A: 540-54-5
1-Chloropropane

B: 106-94-5
propyl bromide

Conditions

Conditions	Yield
With hydrogenchloride; hydrogen bromide Einwirkung von stillen elektrischen Entladungen;
With hydrogenchloride; hydrogen bromide Einwirkung von stillen elektrischen Entladungen;

: 856365-85-0
1-(2-chloro-ethylsulfanyl)-2-propylsulfanyl-ethane

A: 505-29-3
1,4-Dithiane

B: 540-54-5
1-Chloropropane

Conditions

Conditions	Yield
beim Erhitzen;

: 74-98-6
propane

: 540-54-5
1-Chloropropane

Conditions

Conditions	Yield
With chromium nickel; chlorine at 600℃;
With chlorine; tetraethyllead(IV) at 136 - 140℃;
With iodine Chlorierung;

: 616-47-7
1-methyl-1H-imidazole

: 540-54-5
1-Chloropropane

: 79917-89-8
1-methyl-3-propyl-1H-imidazolium chloride

Conditions

Conditions	Yield
at 70℃; for 48h;	99%
at 170℃; Microwave irradiation;	95%
im Rohr;

: 540-54-5
1-Chloropropane

: 88-75-5
2-hydroxynitrobenzene

: 3079-53-6
1-nitro-2-propoxybenzene

Conditions

Conditions	Yield
With potassium carbonate; potassium iodide In acetone a) RT, 24 h, b) reflux, 120 h;	99%

: 540-54-5
1-Chloropropane

: 80825-28-1
bis(4-amino-3-nitrophenyl) disulfide

: 54393-89-4
1-amino-2-nitro-4-n-propylthiobenzene

Conditions

Conditions	Yield
Stage #1: bis(4-amino-3-nitrophenyl) disulfide With sodiumsulfide nonahydrate In methanol for 0.5h; Stage #2: 1-Chloropropane In methanol at 55℃; Temperature;	98.32%

: 17771-33-4
7-hydroxy-2,2-dimethyl-chroman-4-one

: 540-54-5
1-Chloropropane

: 115613-80-4
2,2-Dimethyl-7-propoxy-chroman-4-one

Conditions

Conditions	Yield
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 80℃; for 7h;	96%

: 540-54-5
1-Chloropropane

: 4731-53-7
TOP

: 56155-22-7
C27H58P(1+)*Cl(1-)

Conditions

Conditions	Yield
at 180℃; under 2250.23 Torr; for 0.5h; Microwave irradiation; Inert atmosphere; neat (no solvent);	96%

: 7098-07-9
N-Ethylimidazole

: 540-54-5
1-Chloropropane

: 106-94-5
propyl bromide

: propyl-3-ethylimidazole

Conditions

Conditions	Yield
at 40 - 55℃; for 6h;	95.3%

...Expand

: 540-54-5
1-Chloropropane

: 54009-36-8
2-amino-1-(4-(methylsulfonyl)phenyl)ethanone

: 2-n-propylamino-1-p-methylsulfonylacetophenone

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 5 - 100℃; for 6h; Reagent/catalyst;	95.3%

: 540-54-5
1-Chloropropane

: 123-38-6
propionaldehyde

Conditions

Conditions	Yield
With C30H38Cl2Ir2N4 In dimethyl sulfoxide at 50℃; for 5h;	95%
With oxygen; kieselguhr; copper(l) chloride In dichloromethane for 1.5h; Oxidation; Heating;	91%

: 123-99-9
azelaic acid

: 540-54-5
1-Chloropropane

: 6624-68-6
dipropyl azelate

Conditions

Conditions	Yield
With sodium hydrogencarbonate In propan-1-ol at 40℃; for 1.5h;	95%

: 540-54-5
1-Chloropropane

: 6674-22-2
1,8-diazabicyclo[5.4.0]undec-7-ene

: 1241961-59-0
1-propyl-2,3,4,6,7,8,9,10-octahydropyrimido[1,2-a]azepin-1-ium chloride

Conditions

Conditions	Yield
for 9h; Reflux;	95%

: 540-54-5
1-Chloropropane

: 109-61-5
propoxycarbonyl chloride

: 109-21-7
butyl butyrate

Conditions

Conditions	Yield
Stage #1: 1-Chloropropane With magnesium; 1,2-dibromomethane In toluene at 60℃; for 3h; Inert atmosphere; Stage #2: propoxycarbonyl chloride With aluminum (III) chloride; manganese(ll) chloride In toluene at 0 - 20℃; for 2.25h; Inert atmosphere;	95%

: 540-54-5
1-Chloropropane

: 62-53-3
aniline

: 622-80-0
N-propylaniline

Conditions

Conditions	Yield
With NPs-Fe3O4(at)SiO2(at)[PrMIM]PW In acetonitrile at 50℃; Reagent/catalyst; Solvent; Temperature;	95%

: 540-54-5
1-Chloropropane

: 106092-09-5
(S)-4,5,6,7-tetrahydrobenzo[d]thiazol-2,6-diamine

: 104632-26-0
pramipexole

Conditions

Conditions	Yield
With NPs-Fe3O4(at)SiO2(at)[PrMIM]PW In acetonitrile at 50℃; Reagent/catalyst;	95%

: 540-54-5
1-Chloropropane

: 100-97-0
hexamethylenetetramine

: N-propylhexamethylenetetrammonium chloride

Conditions

Conditions	Yield
at 70℃; Temperature;	94.7%

: 540-54-5
1-Chloropropane

: 281-23-2
adamantane

: 20778-55-6
1-n-propyladamantane

Conditions

Conditions	Yield
With Rh(PPh3)3Cl In dichloromethane at 150℃; for 3h;	94%

: 540-54-5
1-Chloropropane

: 603-35-0
triphenylphosphine

A: 103-65-1
Propylbenzene

B: 7650-84-2
diphenylphosphinopropane

Conditions

Conditions	Yield
Stage #1: triphenylphosphine With lithium In tetrahydrofuran at 20℃; for 3h; Inert atmosphere; Stage #2: 1-Chloropropane In tetrahydrofuran at 5 - 50℃; for 6.25h;	A 93.5% B 91.6%

...Expand

: 540-54-5
1-Chloropropane

: 998-40-3
tributylphosphine

: 63817-66-3
n-propyltributylphosphonium chloride

Conditions

Conditions	Yield
In toluene at 180℃; for 0.5h; Inert atmosphere; Microwave irradiation;	93%
In acetone

: 1019-45-0
N,N-dimethyl-5-methoxytryptamine

: 540-54-5
1-Chloropropane

: [2-(5-methoxy-1-propyl-1H-indol-3-yl)-ethyl]-dimethyl-amine

Conditions

Conditions	Yield
Stage #1: N,N-dimethyl-5-methoxytryptamine With sodium hydride at 100℃; Metallation; Stage #2: 1-Chloropropane In N,N-dimethyl-formamide at 20℃; Alkylation; Further stages.;	93%

: 540-54-5
1-Chloropropane

: 63-74-1
sulfanilamide

: 4-(propylamino)benzenesulfonamide

Conditions

Conditions	Yield
With NPs-Fe3O4(at)SiO2(at)[PrMIM]PW In acetonitrile at 50℃;	93%

: 540-54-5
1-Chloropropane

: 65-85-0
benzoic acid

: 2315-68-6
propyl benzoate

Conditions

Conditions	Yield
With 1,1'-(hexane-1,6-diyl)bis(1,8-diazabicyclo[5.4.0]undec-7-enium) dichlorine In ethanol; water at 70℃; for 2h; Green chemistry;	93%

: 540-54-5
1-Chloropropane

: 62-23-7
4-nitro-benzoic acid

: 94-22-4
propyl 4-nitrobenzoate

Conditions

Conditions	Yield
With 1,1'-(hexane-1,6-diyl)bis(1,8-diazabicyclo[5.4.0]undec-7-enium) dichlorine In ethanol; water at 70℃; for 2h; Green chemistry;	93%

: 540-54-5
1-Chloropropane

: 124-38-9
carbon dioxide

: 75-04-7
ethylamine

: 39054-40-5
1-propyl ethylcarbamate

Conditions

Conditions	Yield
With choline chloride * 2ZnCl2 at 20℃; under 760.051 Torr; for 2h; Green chemistry;	93%

...Expand

1-Chloropropane Chemical Properties

Molecular Structure:

Molecular Formula: C₃H₇Cl
Molecular Weight: 78.5407
IUPAC Name: 1-Chloropropane
Synonyms of Propyl chloride (CAS NO.540-54-5): 1-Chloropropane ; 4-01-00-00189 (Beilstein Handbook Reference) ; AI3-28788 ; BRN 1730771 ; CCRIS 9257 ; EINECS 208-749-7 ; HSDB 5681 ; N-Propyl chloride ; Propane, 1-chloro- ; Propyl chloride [UN1278] [Flammable liquid] ; UN1278
CAS NO: 540-54-5
Classification Code: Organics ; Alkyl Chlorides ; Monofunctional & alpha,omega-Bifunctional Alkanes ; Monofunctional Alkanes
Melting point: -123 °C
Index of Refraction: 1.381
Molar Refractivity: 20.79 cm³
Molar Volume: 89.4 cm³
Surface Tension: 20.3 dyne/cm
Density: 0.878 g/cm³
Enthalpy of Vaporization: 27.18 kJ/mol
Boiling Point: 46.8 °C at 760 mmHg
Vapour Pressure: 343 mmHg at 25°C

1-Chloropropane Uses

Propyl chloride (CAS NO.540-54-5) is used in organic synthesis, pesticide, pharmaceutical intermediate and used as chemical intermediate for n-propylamine (former use).

1-Chloropropane Production

Product Categories about Propyl chloride (CAS NO.540-54-5) are Organics;Alkyl Chlorides;Monofunctional & alpha,omega-Bifunctional Alkanes;Monofunctional Alkanes.

1-Chloropropane Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
rat	LD50	oral	> 2gm/kg (2000mg/kg)		Mutation Research. Vol. 101, Pg. 321, 1982.

1-Chloropropane Consensus Reports

Reported in EPA TSCA Inventory.

1-Chloropropane Safety Profile

Hazard Codes of Propyl chloride (CAS NO.540-54-5): F, Harmful Xn
Risk Statements: 11-20/21/22
R11: Highly flammable.
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 9-29
S9: Keep container in a well-ventilated place.
S29: Do not empty into drains.
RIDADR: UN 1278 3/PG 2
WGK Germany: 3
RTECS: TX4400000
HazardClass: 3.1
PackingGroup: II
A moderately poisonous irritant to skin, eyes, and mucous membranes. Narcotic in high concentrations. Flammable liquid and dangerous fire hazard when exposed to heat, flame, or oxidizers. Moderately explosive when exposed to flame. Keep away from heat and open flame; can react vigorously with oxidizing materials. To fight fire, use CO₂, dry chemical. When heated to decomposition it emits toxic fumes of Cl⁻. See also CHLORINATED HYDROCARBONS, ALIPHATIC.

1-Chloropropane Standards and Recommendations

DOT Classification: 3; Label: Flammable Liquid

1-Chloropropane Specification

1. Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
2. Handling: Wash thoroughly after handling. Use only in a well ventilated area. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
3. Personal Protection: Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
4. Fire Fighting: Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may spread fire. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use foam, dry chemical, or carbon dioxide.
5. Reactivity Profile: 1-Chloropropane presents a dangerous fire risk. May be incompatible with strong oxidizing and reducing agents. Incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

Product Name

n-Propyl chloride

Synthetic route

1-Chloropropane Chemical Properties

1-Chloropropane Uses

1-Chloropropane Production

1-Chloropropane Toxicity Data With Reference

1-Chloropropane Consensus Reports

1-Chloropropane Safety Profile

1-Chloropropane Standards and Recommendations

1-Chloropropane Specification

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