1-Indanone supplier | CasNO.83-33-0

Name
1-Indanone
EINECS 201-470-1
CAS No. 83-33-0
Article Data477
CAS DataBase
Density 1.148 g/cm³
Solubility 6.5 g/L (20°C) in water
Melting Point 38-40 °C
Formula C₉H₈O
Boiling Point 244 °C at 760 mmHg
Molecular Weight 132.162
Flash Point 111.7 °C
Transport Information
Appearance pale yellow liquid
Safety 22-24/25-36-26
Risk Codes 22-36/37/38
Molecular Structure
Hazard Symbols Xi,Xn
Synonyms alpha-indanone;Hydrindone;r-Hydrindone;alpha-hydrindone;1H-Inden-1-one, 2,3-dihydro-;2,3-dihydroinden-1-one;1H-Inden-1-one,2,3-dihydro-;Indanone (VAN);Indan-1-one;1-Indone;2,3-Dihydro-1H-inden-1-one;1-Indanone(1H-Inden-1-one,2,3-dihydro-);
PSA 17.07000
LogP 1.81550

Synthetic route

: 501-52-0
3-Phenylpropionic acid

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With trifluorormethanesulfonic acid In dichloromethane at 80℃; for 3h; Friedel-Crafts Acylation; High pressure; Inert atmosphere; Green chemistry;	100%
With trifluorormethanesulfonic acid at 5 - 20℃; for 2h; Cyclization;	99%
With polyphosphoric acid at 90℃; for 0.5h;	98.2%

: 68253-35-0, 100485-57-2, 3349-60-8
indan-1-one oxime

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With potassium permanganate; tungstate sulfuric acid In dichloromethane; water at 20℃; for 0.133333h;	94%
With diphenyl ditelluride; oxygen In ethyl acetate for 24h; Irradiation;	94%
With water; 2-nitro-4,5-dichloropyridazin-3(2H)-one In methanol at 150℃; under 10336 Torr; for 0.166667h; Microwave irradiation;	90%

: 6351-10-6
1-Indanol

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With iodosylbenzene; potassium bromide In water for 2h; Oxidation;	100%
With cerium(III) sulfate; barium bromate In water; acetonitrile for 2h; Heating;	100%
With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In ethyl acetate at 80℃;	100%

: 95-13-6
1-indene

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With dihydrogen peroxide In water at 75℃; for 12h;	100%
With tert.-butylhydroperoxide; C21H19N5Pd(2+)*2BF4(1-) In decane; acetonitrile at 70℃; for 24h; Temperature; Wacker Oxidation;	95%
With iron(II) chloride In ethanol at 80℃; for 6h;	93%

: 496-11-7
INDANE

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; C24H18N6O3Cu(1+)I(1-) In water at 20℃; for 4h; Reagent/catalyst;	98%
With tert.-butylhydroperoxide; copper(II) choride dihydrate; tetrabutyl-ammonium chloride; sodium carbonate; 2,2′‐biquinoline‐4,4′‐dicarboxylic acid dipotassium salt In water at 20℃; for 17h; Green chemistry;	98%
With tert.-butylhydroperoxide; 0.5C34H18N16(4-)2H2O2Cu(1+)*C3H7NO In water at 20℃; for 4h; Reagent/catalyst; Sonication;	97%

: 501-52-0
3-Phenylpropionic acid

A: C18H16O2

B: 83-33-0
inden-1-one

Conditions

Conditions	Yield
Stage #1: 3-Phenylpropionic acid With trifluoroacetic anhydride In dichloromethane at 20℃; for 0.25h; Stage #2: With trifluorormethanesulfonic acid In dichloromethane at 20℃; for 0.5h;	A n/a B 94%
Stage #1: 3-Phenylpropionic acid With trifluoroacetic anhydride In dichloromethane at 20℃; for 0.25h; Stage #2: With trifluorormethanesulfonic acid In dichloromethane at 20℃; for 2h;	A 75% B 16%

: 13225-61-1
1,7-diphenyl-4-oxahepta-1,6-diyne

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With water; PtCl4-CO In tetrahydrofuran at 80℃; under 1034.3 Torr; for 1.5h;	94%

: 201230-82-2
carbon monoxide

: 4840-91-9
o-iodostyrene

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With pyridine; palladium diacetate; tetrabutyl-ammonium chloride In N,N-dimethyl-formamide at 100℃; under 760 Torr; for 8h;	100%

: 40774-41-2
3-Bromoindan-1-one

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With water; zinc In acetonitrile at 25℃; for 6h; Sealed tube; Inert atmosphere;	62%
With water; zinc In acetonitrile at 25℃; for 6h; Inert atmosphere; Sealed tube;	62%

: 6351-10-6
1-Indanol

A: 697-64-3
(R)-indan-1-ol

B: 25501-32-0
(S)-indanol

C: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With palladium dichloro (η-2,5-norbornadiene); oxygen; (-)-sparteine In toluene at 60℃; for 54h; Title compound not separated from byproducts;	A n/a B n/a C 63%
With 3 A molecular sieve; oxygen; (-)-sparteine; palladium dichloro (η-2,5-norbornadiene) In toluene at 60℃; under 760 Torr; for 54h;	A n/a B n/a C 63%
With (1R)-N-oxyl-1-(N-benzylcarbamoyl)-8-azabicyclo[3.2.1]octane; sodium hydrogencarbonate; sodium bromide In dichloromethane; water at 0℃; Electrochemical reaction; optical yield given as %ee; enantioselective reaction;	A n/a B n/a C 53%

...Expand

: 496-11-7
INDANE

A: 6351-10-6
1-Indanol

B: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With N-hydroxyphthalimide; oxygen; butane-2,3-dione dioxime In acetonitrile at 80℃; under 3750.38 Torr; for 8h;	A 10.4% B 75.3%
With N-hydroxyphthalimide; 1,4-diamino-2,3-dichloroanthraquinone; oxygen In acetonitrile at 80℃; under 1875.15 - 2250.18 Torr; for 6h;	A 15 % Chromat. B 64%
With 1H-imidazole; sodium periodate; Mn(TDCPP)OAc In dichloromethane for 24h; Ambient temperature;	A 26% B 60%

: 78196-99-3
2-(phenylthio)-2,3-dihydro-1H-inden-1-one

A: 83-33-0
inden-1-one

B: 882-33-7
diphenyldisulfane

Conditions

Conditions	Yield
With formic acid; (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; N-ethyl-N,N-diisopropylamine In ethanol at 20℃; Irradiation; chemoselective reaction;	A 36% B 25%

: 201230-82-2
carbon monoxide

: 2170-06-1
1-Phenyl-2-(trimethylsilyl)acetylene

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With water; triethylamine; triphenylphosphine; chloro(1,5-cyclooctadiene)rhodium(I) dimer In tetrahydrofuran at 160℃; under 51485.6 Torr; for 4h;	61%

: 19455-83-5
1H-inden-3-yl acetate

A: 83-33-0
inden-1-one

B: 879-35-6
(R)-1-indanyl acetate

Conditions

Conditions	Yield
With Novozym 435; 2,6-dimethyl-4-heptanol; (Ph4C4CO)2H(μ-H)(CO)4Ru2 In toluene at 70℃; for 72h; Reduction; Enzymatic reaction;	A 13 % Spectr. B 85%

: 1-hydroxy-2,3-dihydro-1H-indene-1-carboxylic acid

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With diethylamino-sulfur trifluoride In dichloromethane at -78 - 20℃; for 4.5h; Inert atmosphere;	37%

: 2-(hydroxy-p-tolyl-methylene)indan-1-one

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With indium(III) triflate In butan-1-ol for 6h; Solvent; Reflux;	86%

: 2-(hydroxy-o-tolyl-methylene)indan-1-one

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With indium(III) triflate In butan-1-ol for 6h; Reflux;	88%

: 2-[hydroxy-(4-methoxyphenyl)methylene]indan-1-one

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With indium(III) triflate In butan-1-ol for 12h; Reflux;	85%

: 2-[(4-chlorophenyl)hydroxymethylene]indan-1-one

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With indium(III) triflate In butan-1-ol for 6h; Reflux;	90%

: 2-(hydroxypyridin-3-yl-methylene)indan-1-one

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With indium(III) triflate In butan-1-ol for 4h; Reflux;	86%

: 28272-96-0
2-vinylbenzaldehyde

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With bis(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; 6-diphenylphosphinomethyl-3-methyl-2-aminopyridine In toluene at 150℃; for 1h; Inert atmosphere;	97%
With acetic acid; L-proline at 120℃; for 24h; Green chemistry;	45%
(iPrO)Ti(μ:η1,η1-OCMe2CH2PPh2)RhCl In dichloromethane at 25℃; for 11h;	40%

: 1-(1-ethoxyethoxy)indene

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With sodium carbonate; acetic acid In methanol; water	82.4%

: 2039-88-5
2-bromostyrene

molybdenum hexacarbonyl: molybdenum hexacarbonyl

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With pyridine; tetrabutyl-ammonium chloride; tri tert-butylphosphoniumtetrafluoroborate; palladium diacetate In 1,4-dioxane at 150℃; for 0.333333h; microwave irradiation;	75%

: (E)-2,3-dihydro-1H-inden-1-one O-acetyloxime

A: 10277-74-4, 34698-41-4, 61341-86-4, 61949-83-5
(S)-1-Aminoindane

B: 10277-74-4
(R)-1-Aminoindane

C: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With [Rh(OH)(cod)]2; Ureaphos-2; hydrogen; caesium carbonate In isopropyl alcohol at 55℃; under 97509.8 Torr; for 17h; Reagent/catalyst; Schlenk technique; Autoclave; Optical yield = < 2 %ee;	A n/a B n/a C 6 %Chromat.

...Expand

: 6351-10-6
1-Indanol

A: 25501-32-0
(S)-indanol

B: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With sodium hydrogencarbonate; sodium bromide; chiral azabicyclo-N-oxyl In dichloromethane at 0℃; Electrochemical reaction;	A n/a B 52%
With C32H36IrNO2S In cyclohexanone at 30℃; for 7h; optical yield given as %ee; enantioselective reaction;	A 50% B n/a
With C50H42ClN2O3Ru In chloroform at 25℃; Kinetics; Time; Reagent/catalyst; Molecular sieve; Resolution of racemate; enantioselective reaction;	A 33.7% B n/a

: 27326-43-8
2-vinylbenzoic acid

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With potassium phosphate; fac-tris(2-phenylpyridinato-N,C2')iridium(III); tris-(trimethylsilyl)silane; dimethyl dicarbonate In acetonitrile at 20℃; for 24h; Inert atmosphere; Schlenk technique; Irradiation; Sealed tube;	76%
Multi-step reaction with 2 steps 1: 56 percent / tributylphosphine / CH2Cl2 / 4 h / -30 °C 2: 56 percent / Bu3SnH; AIBN / benzene / 10 h / Heating View Scheme

: 52427-11-9
3-(4-methoxyphenyl)-2-methylpropionic acid

A: 5464-10-8
6-methoxy-2-methylindanone

B: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With PPA
With PPA
With PPA In (2S)-N-methyl-1-phenylpropan-2-amine hydrate
With PPA
With PPA

: 201230-82-2
carbon monoxide

: 2170-06-1
1-Phenyl-2-(trimethylsilyl)acetylene

A: 104-53-0
3-phenyl-propionaldehyde

B: 59556-86-4
2-Phenyl-3-(trimethylsilyl)-propanal

C: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With hydrogen; triethylamine; triphenylphosphine; chloro(1,5-cyclooctadiene)rhodium(I) dimer In tetrahydrofuran at 160℃; under 36775.4 Torr; for 4h;	A 25% B 36% C 10%

...Expand

: 95-13-6
1-indene

A: 92799-73-0
1-indanyl hydroperoxide

B: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With triethylsilane; oxygen; [5,10,15,20-tetrakis(2,6-dichlorophenyl)porphinato]cobalt(II) In dichloromethane; isopropyl alcohol at 28℃; under 760 Torr; for 1.5h;	A 60% B n/a

: 14381-42-1
Indan-1-carboxylic acid

: 83-33-0
inden-1-one

Conditions

Conditions	Yield
With (2,2'-dipyridyl)bis(5-methyl-2-(4-fluoro)phenylpyridine-N,C)iridium(III) hexafluorophosphate; oxygen; sodium carbonate; 1,1'-diethyl-4,4'-bipyridinium diperchlorate In dimethyl sulfoxide at 20℃; under 760.051 Torr; for 16h; Irradiation;	77%
With iron(III) chloride; oxygen In N,N-dimethyl-formamide at 110℃;	49%

: 83-33-0
inden-1-one

: 548-35-6
truxene

Conditions

Conditions	Yield
With hydrogenchloride; acetic acid In water at 100℃; for 16h;	100%
With hydrogenchloride; acetic acid at 100℃; for 16h;	98%
With hydrogenchloride; acetic acid In water at 120℃; for 10h;	90%

: 83-33-0
inden-1-one

: 6351-10-6
1-Indanol

Conditions

Conditions	Yield
With 15percent aqueous acidic TiCl3; 30percent aqueous NH3 In methanol at 0 - 20℃; for 0.0833333h;	100%
With sodium tetrahydroborate	99%
With C15H18BF3; hydrogen; tert-butylimino-tri(pyrrolidino)phosphorane In tetrahydrofuran at 75℃; under 75007.5 Torr; for 20h; Glovebox;	99%

: 83-33-0
inden-1-one

: 68253-35-0, 100485-57-2, 3349-60-8
indan-1-one oxime

Conditions

Conditions	Yield
With hydroxylamine hydrochloride	100%
With hydroxylamine hydrochloride In ethanol at 20 - 25℃; for 0.166667h;	91.6%
With hydroxylamine hydrochloride; sodium hydroxide In ethanol at 20 - 25℃; for 1h;	91.6%

: 83-33-0
inden-1-one

: 25501-32-0
(S)-indanol

Conditions

Conditions	Yield
With dimethylsulfide borane complex; (3aR)-1-methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2-c][1,3,2]oxazaborole In tetrahydrofuran at 0℃; for 0.5h; enantioselective reaction;	100%
With formic acid; [RuCl2(hexamethylbenzene)]2; (S)-2-piperidinemethanethiol hydrochloride; triethylamine at 30℃; for 24h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%
With formic acid; triethylamine at 28℃; for 48h; enantioselective reaction;	99%

: 2801-93-6
1-amino-buten-1-en-3-one

: 83-33-0
inden-1-one

: 18631-19-1
3-methyl-4-azafluorene

Conditions

Conditions	Yield
With acetic acid at 120℃; for 20h;	100%

: 83-33-0
inden-1-one

: 697-64-3
(R)-indan-1-ol

Conditions

Conditions	Yield
With (1R,2R)-PhCH(NH2)CH(Ph)NH-p-SO2-C6H4-CH2CH2-silica gel; tetrabutylammomium bromide; sodium formate; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 at 40℃;	100%
With dimethylsulfide borane complex; (S)-1-methyl-3,3-diphenyl-hexahydropyrrolo[1,2-c][1,3,2]oxazaborole In tetrahydrofuran at 0℃; for 0.5h; enantioselective reaction;	100%
With formic acid; C38H40ClN2O2RhS; triethylamine In neat (no solvent) at 24 - 30℃; for 5h; Reagent/catalyst; Inert atmosphere; enantioselective reaction;	100%

: 83-33-0
inden-1-one

: 100-51-6
benzyl alcohol

: 16307-30-5
2-benzyl-1-indanone

Conditions

Conditions	Yield
With titanium(IV) oxide; potassium hydroxide In toluene at 100℃; for 10h; Sealed tube; Irradiation;	100%
With dichloro[1,3‐diethyl(5,6‐dimethyl)benzimidazolin‐2‐ylidene](benzene)ruthenium (II); sodium hydroxide In toluene at 105℃; for 8h;	88%
With bis(μ-chloro)-bis[1,3-di(2-pyridyl)-4,6-dimethylbenzene-N,C(2'),N-iridium chloride]; caesium carbonate In tert-Amyl alcohol for 12h; Reflux;	87%

: 383-63-1
ethyl trifluoroacetate,

: 83-33-0
inden-1-one

: lithium 3-(trifluoroacetyl)indanonate

Conditions

Conditions	Yield
With ethanol; lithium hydride In benzene Reflux; Inert atmosphere;	100%

: 83-33-0
inden-1-one

: 563-96-2
2,2-dihydroxyacetic acid

: 114915-75-2
1-oxoindan-Δ2,α-acetic acid

Conditions

Conditions	Yield
With sulfuric acid Inert atmosphere;	100%

: 500-22-1
3-pyridinecarboxaldehyde

: 83-33-0
inden-1-one

: 4875-90-5
2-(pyridin-3-ylmethylene)-2,3-dihydro-1H-inden-1-one

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; water at 0℃; Claisen-Schmidt Condensation;	99.8%
With sodium hydroxide In methanol at 20℃; for 12h;

: 500-22-1
3-pyridinecarboxaldehyde

: 83-33-0
inden-1-one

: 4875-90-5
(2E)-2-(pyridin-3-ylmethylidene)-2,3-dihydro-1H-inden-1-one

Conditions

Conditions	Yield
Stage #1: 3-pyridinecarboxaldehyde; inden-1-one In ethanol for 0.0833333h; Inert atmosphere; Stage #2: With sodium hydroxide In ethanol; water for 0.5h; Inert atmosphere;	99.8%
With sodium hydroxide In ethanol; water at 0℃; Claisen-Schmidt Condensation;	73%
In methanol at 20℃; Alkaline conditions;	29%

: 587-04-2
3-Chlorobenzaldehyde

: 83-33-0
inden-1-one

: 5706-17-2
(E)-2-(4-chlorobenzylidene)-indan-1-one

Conditions

Conditions	Yield
Stage #1: m-Chlorobenzaldehyde; inden-1-one In ethanol for 0.0833333h; Inert atmosphere; Stage #2: With sodium hydroxide In ethanol; water for 0.5h; Inert atmosphere;	99.7%

: 872-85-5
pyridine-4-carbaldehyde

: 83-33-0
inden-1-one

: 4875-89-2
(E)-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one

Conditions

Conditions	Yield
Stage #1: pyridine-4-carbaldehyde; inden-1-one In ethanol for 0.0833333h; Inert atmosphere; Stage #2: With sodium hydroxide In ethanol; water for 0.5h; Inert atmosphere;	99.4%
With piperidine; acetic acid at 130℃; for 1.5h;	34%

: 872-85-5
pyridine-4-carbaldehyde

: 83-33-0
inden-1-one

: 4875-89-2
2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; water at 0℃; Claisen-Schmidt Condensation;	99.4%

: 89-98-5
2-chloro-benzaldehyde

: 83-33-0
inden-1-one

: 103457-37-0
(E)-2-(2-chlorobenzylidene)-2,3-dihydro-1H-inden-1-one

Conditions

Conditions	Yield
Stage #1: 2-chloro-benzaldehyde; inden-1-one In ethanol for 0.0833333h; Inert atmosphere; Stage #2: With sodium hydroxide In ethanol; water for 0.5h; Inert atmosphere;	99.2%
With sodium hydroxide In ethanol for 3h;	84%

: 83-33-0
inden-1-one

: 613-45-6
2,4-Dimethoxybenzaldehyde

: (E)-2-(2,4-dimethoxybenzyliden)-2,3-dihydro-1H-inden-1-one

Conditions

Conditions	Yield
With hydrogenchloride; acetic acid at 20℃; for 24h;	99.1%
basic condition;
Claisen-Schmidt Condensation; Alkaline conditions;

: 83-33-0
inden-1-one

: 74-88-4
methyl iodide

: 10489-28-8
2,2-dimethyl-indan-1-one

Conditions

Conditions	Yield
Stage #1: inden-1-one With sodium hydride In N,N-dimethyl-formamide for 1h; Stage #2: methyl iodide In N,N-dimethyl-formamide for 1.5h;	99%
Stage #1: inden-1-one With sodium hydride In 1,2-dimethoxyethane at 10 - 35℃; for 0.166667h; Stage #2: methyl iodide In 1,2-dimethoxyethane at 10 - 35℃; for 1h;	99%
Stage #1: inden-1-one With sodium hydride In 1,2-dimethoxyethane at 20℃; for 0.166667h; Stage #2: methyl iodide In 1,2-dimethoxyethane at 20℃; for 1h;	99%

: 83-33-0
inden-1-one

: 7749-02-2
2,2-dibromoindan-1-one

Conditions

Conditions	Yield
With N-Bromosuccinimide; toluene-4-sulfonic acid at 80℃; for 1h;	99%
With bromine In acetic acid at 100℃; for 0.75h;	97%
With hydrogen bromide; dihydrogen peroxide In methanol; water for 20h; Heating;	89%

: 83-33-0
inden-1-one

: 1775-27-5
2-bromoindanone

Conditions

Conditions	Yield
	99%
With bromine In diethyl ether Cooling with ice;	99%
With copper bromide In chloroform; ethyl acetate for 1h; Reflux;	96%

: 7677-24-9
trimethylsilyl cyanide

: 83-33-0
inden-1-one

: 31928-65-1
1-((trimethylsilyl)oxy)-2,3-dihydro-1H-indene-1-carbonitrile

Conditions

Conditions	Yield
With 4-methylmorpholine N-oxide In dichloromethane at 20℃; for 18h;	99%
Stage #1: inden-1-one With scandium tris(trifluoromethanesulfonate); 1-n-butyl-3-methylimidazolium hexafluoroantimonate at 20℃; for 0.166667h; Stage #2: trimethylsilyl cyanide at 20℃; for 2h; Inert atmosphere;	99%
With C29H46LaN3Si2 at 15℃; for 24h; Inert atmosphere; Glovebox; Schlenk technique;	99%

: 83-33-0
inden-1-one

: 616-38-6
carbonic acid dimethyl ester

: 22955-77-7
methyl 1-indanone-2-carboxylate

Conditions

Conditions	Yield
With sodium hydride In tetrahydrofuran at 20℃; for 2h; Inert atmosphere;	99%
With sodium hydride In toluene; mineral oil at 0 - 120℃; for 18h;	95%
With sodium hydride In tetrahydrofuran; mineral oil for 2h; Reflux; Inert atmosphere;	93%

: 83-33-0
inden-1-one

A: 697-64-3
(R)-indan-1-ol

B: 25501-32-0
(S)-indanol

Conditions

Conditions	Yield
With dimethylsulfide borane complex; (S)-2-(anilinodiphenylmethyl)pyrrolidine In tetrahydrofuran at 20℃; for 2h; enantioselective reaction;	A 99% B n/a
With dimethylsulfide borane complex In tetrahydrofuran at 20℃; for 2h; enantioselective reaction;	A 96% B n/a
With sprouted Pisum sativa In water at 25℃; for 58h; optical yield given as %ee; enantioselective reaction;	A n/a B 42%

: 127-19-5
N,N-dimethyl acetamide

: 83-33-0
inden-1-one

: 1579-15-3
2-acetoxyindan-1-one

Conditions

Conditions	Yield
Stage #1: N,N-dimethyl acetamide; inden-1-one With trifluorormethanesulfonic acid; thallium(III) acetate at 60℃; for 0.333333h; Stage #2: With water for 0.166667h; Further stages.;	99%

: 83-33-0
inden-1-one

: 90271-93-5
β-bromoindenone

Conditions

Conditions	Yield
Stage #1: inden-1-one With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) In tetrachloromethane for 2h; Heating; irradiation; Stage #2: With triethylamine In tetrachloromethane at 0 - 20℃; for 12h;	99%
Stage #1: inden-1-one With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) In tetrachloromethane for 2h; Photolysis; Reflux; Stage #2: With triethylamine In tetrachloromethane at 0℃; for 9h;	95%
Stage #1: inden-1-one With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) In tetrachloromethane for 2.5h; Reflux; Stage #2: With triethylamine In tetrachloromethane at 0℃;	85%

lithium bis isopropoxyamide (LDA): lithium bis isopropoxyamide (LDA)

: 60556-33-4
N-(tert-butyl)-N-(1-chloro-1,1-dimethylsilyl)amine

: 83-33-0
inden-1-one

: 308846-97-1
N-(tert-butyl)-N-(1-(1H-3-indenyloxy)-1,1-dimethylsilyl)amine

Conditions

Conditions	Yield
In tetrahydrofuran	99%

...Expand

1-Indanone Chemical Properties

IUPAC Name: 2,3-Dihydroinden-1-one
Synonyms of 1-Indanone (CAS NO.83-33-0): 1-Indone ; 2,3-Dihydro-1H-inden-1-one ; alpha-Hydrindone ; alpha-Indanone ; 1H-Inden-1-one, 2,3-dihydro-
CAS NO: 83-33-0
Molecular Formula: C₉H₈O
Molecular Weight: 132.16
Molecular Structure:
EINECS: 201-470-1
H bond acceptors: 1
H bond donors: 0
Freely Rotating Bonds: 0
Polar Surface Area: 17.07 Å²
Index of Refraction: 1.585
Molar Refractivity: 38.55 cm³
Molar Volume: 115 cm³
Surface Tension: 44.8 dyne/cm
Density: 1.148 g/cm³
Flash Point: 111.7 °C
Enthalpy of Vaporization: 48.1 kJ/mol
Boiling Point: 244 °C at 760 mmHg
Vapour Pressure: 0.0311 mmHg at 25°C
Melting point : 38-40 °C
Water Solubility: 6.5 g/L (20°C)
Appearance: Pale yellow liquid
Product Categories of 1-Indanone (CAS NO.83-33-0): Drug Intermediates;Indane/Indanone and Derivatives;Indanone & Indene;Fused Ring Systems

1-Indanone Safety Profile

Safety Information about 1-Indanone (CAS NO.83-33-0):
Hazard Codes: Harmful Xn,Xi
Risk Statements: 22-36/37/38
R22: Harmful if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 22-24/25-36-26
S22: Do not breathe dust.
S24/25: Avoid contact with skin and eyes.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29143900

1-Indanone Specification

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media: In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.
Storage: Store in a cool, dry place. Keep container closed when not in use.

Product Name

1-Indanone

Synthetic route

1-Indanone Chemical Properties

1-Indanone Safety Profile

1-Indanone Specification

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