2-Aminobenzophenone supplier

Name
2-Aminobenzophenone
EINECS 220-613-9
CAS No. 2835-77-0
Article Data160
CAS DataBase
Density 1.161 g/cm³
Solubility practically insoluble in water
Melting Point 103-107 °C(lit.)
Formula C₁₃H₁₁NO
Boiling Point 383.7 °C at 760 mmHg
Molecular Weight 197.236
Flash Point 185.9 °C
Transport Information
Appearance yellow-gold fine crystalline powder
Safety 26-36-37/39
Risk Codes 22-36/37/38
Molecular Structure
Hazard Symbols Xn,Xi
Synonyms Benzophenone,2-amino- (6CI,7CI,8CI);(2-Aminophenyl)phenylmethanone;2-Benzoylaniline;2-Benzoylbenzenamine;NSC 9422;o-Aminobenzophenone;o-Aminophenyl phenyl ketone;o-Benzoylaniline;
PSA 43.09000
LogP 3.08100

Synthetic route

: 1859-71-8
2-(tosylamino)benzophenone

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
Stage #1: 2-(tosylamino)benzophenone With sulfuric acid at 0 - 20℃; for 2h; Inert atmosphere; Schlenk technique; Stage #2: With sodium hydrogencarbonate Inert atmosphere; Schlenk technique;	100%
With sulfuric acid at 120℃; for 0.25h;	6.63 g
With sulfuric acid; water at 120℃; for 0.25h;

: 13209-38-6
(2-aminophenyl)(phenyl)methanol

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With bismuth (III) nitrate pentahydrate; cellulose supported copper(0); oxygen In acetonitrile at 60℃; for 0.5h;	98%
With copper(II) chloride monohydrate; potassium carbonate In N,N-dimethyl-formamide at 60℃; for 24h;

: 111838-36-9
4-ethoxy-4-phenyl-1,4-dihydro-3,1-benzoxazin-2(1H)-one

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With sulfuric acid for 0.25h; Ambient temperature;	96.6%

: 2243-79-0
2-nitrobenzophenone

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With sodium tetrahydroborate In water at 40℃; for 2h; chemoselective reaction;	95%
With iron; acetic acid
With nickel; ethyl acetate Hydrogenation;

: 2-Aminobenzophenone N,N-dimethylhydrazone

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With potassium carbonate; dimethyl sulfate In acetonitrile Heating;	95%
With triethylene diamine nickel thiosulfate; water In chloroform at 20℃; for 0.166667h; Hydrolysis;	92%

: 5176-12-5
(2-nitrophenyl)phenylmethanol

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With palladium on activated charcoal; hydrogen; acetic acid In methanol at 20℃; under 760.051 Torr; for 5h;	95%
Multi-step reaction with 3 steps 1: 93 percent / MnO2 / CH2Cl2 / 20 h / Heating 2: 73 percent / hydroxylamine hydrochloride / ethanol; pyridine / 30 h / Heating 3: 17 percent / CO; pentamethylcyclopentadienyl dicarbonyl iron(II) dimer / dioxane / 75 h / 150 °C / 38000 Torr View Scheme

: 5176-14-7
3-phenyl-2,1-benzoxazole

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen; triethylamine In tetrahydrofuran at 25℃; under 7500.75 Torr; for 12h; Autoclave;	95%
With samarium diiodide In tetrahydrofuran at 60℃;	60%

: 16714-27-5
(2-azidophenyl)(phenyl)methanone

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With ammonia; iron(II) sulfate In methanol; water at 20℃; for 2.5h; Reduction;	94%
With methanol; sodium sulfide for 0.166667h;	70%

: 1885-29-6
anthranilic acid nitrile

: 98-80-6
phenylboronic acid

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With 5,5'-dimethyl-2,2'-bipyridine; methanesulfonic acid; palladium(II) trifluoroacetate; water In 2-methyltetrahydrofuran at 80℃; for 36h; Catalytic behavior; Solvent; Reagent/catalyst; Schlenk technique;	93%
With [2,2]bipyridinyl; potassium fluoride; acetic acid; palladium diacetate In tetrahydrofuran at 80℃; for 48h;	31%
With potassium fluoride; 5,5'-dimethyl-2,2'-bipyridine; bis(acetylacetonato)palladium(II); trifluorormethanesulfonic acid In N,N-dimethyl-formamide at 80℃; for 48h; Sealed tube; Schlenk technique;	11%
With [2,2]bipyridinyl; methanesulfonic acid; palladium diacetate In tetrahydrofuran
With [2,2]bipyridinyl; methanesulfonic acid; palladium(II) trifluoroacetate In tetrahydrofuran; water at 80℃; for 36h;

: 201230-82-2
carbon monoxide

: 615-43-0
2-iodophenylamine

: 98-80-6
phenylboronic acid

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
Stage #1: 2-iodophenylamine; phenylboronic acid With potassium carbonate In toluene for 0.166667h; Suzuki cross-coupling reaction; Autoclave; Stage #2: carbon monoxide In toluene at 100℃; under 5171.62 Torr; for 10h; Suzuki cross-coupling reaction; Autoclave;	93%
With potassium carbonate In methoxybenzene at 80℃; under 760.051 Torr; for 12h; carbonylative Suzuki-Miyaura cross-coupling;	89%
With potassium carbonate under 11251.1 Torr; for 0.5h; Suzuki-Miyaura Coupling; Autoclave; Reflux;	89%

...Expand

: 13141-38-3
2-phenylethynylaniline

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With potassium tert-butylate; oxygen; copper diacetate In toluene at 100℃; under 760.051 Torr; for 12h;	92%
Multi-step reaction with 2 steps 1: copper diacetate; potassium tert-butylate; oxygen / dimethyl sulfoxide / 24 h / 120 °C / 760.05 Torr 2: copper diacetate; potassium tert-butylate; oxygen / dimethyl sulfoxide / 24 h / 120 °C / 760.05 Torr View Scheme
Multi-step reaction with 2 steps 1: benzonitrile; copper diacetate; potassium tert-butylate / dimethyl sulfoxide / 24 h / 120 °C / Inert atmosphere 2: copper diacetate; potassium tert-butylate; oxygen / dimethyl sulfoxide / 24 h / 120 °C / 760.05 Torr View Scheme

: 124522-52-7
pyridine-2-carboxylic acid(2-benzoyl-phenyl)-amide

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With ethanol; sodium hydroxide at 70℃; for 3h;	91%

: 873-55-2
sodium benzenesulfonate

: 1885-29-6
anthranilic acid nitrile

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With [2,2]bipyridinyl; p-nitrobenzenesulfonic acid; palladium diacetate In tetrahydrofuran; water at 80℃; for 48h; Reagent/catalyst; Solvent; Inert atmosphere; Schlenk technique;	91%

: 615-43-0
2-iodophenylamine

: 199620-14-9, 13007-92-6
chromium(0) hexacarbonyl

: 98-80-6
phenylboronic acid

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With sodium t-butanolate In N,N-dimethyl acetamide at 80℃; for 0.833333h; Suzuki Coupling;	91%

...Expand

: 91148-63-9
4-methoxy-4-phenyl-1,2-dihydro-3,1-benzoxazine-2(4H)-one

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With sulfuric acid for 0.25h; Ambient temperature;	88.2%

: 118-92-3
anthranilic acid

: 71-43-2
benzene

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With trifluorormethanesulfonic acid; tris(methyl salicylate)phoshate ester at 20℃; for 0.333333h; Reagent/catalyst; chemoselective reaction;	88%
With trifluorormethanesulfonic acid; tris(methyl salicylate)phoshate ester at 20℃; for 0.333333h;	88%
With PPA In dichloromethane at 80℃; for 2h; Friedel-Crafts acylation;	48%

: 1885-29-6
anthranilic acid nitrile

: 71-43-2
benzene

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
Stage #1: anthranilic acid nitrile; benzene With trifluorormethanesulfonic acid In dichloromethane at 60 - 80℃; Houben-Housch synthesis; Inert atmosphere; Stage #2: With water In dichloromethane Houben-Housch synthesis; Inert atmosphere; Cooling with ice; Stage #3: With sodium hydroxide In water Inert atmosphere;	88%

: 67-66-3
chloroform

: 615-43-0
2-iodophenylamine

: 98-80-6
phenylboronic acid

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With potassium hydroxide In toluene at 60℃; for 8h; Suzuki-Miyaura Coupling; Sealed tube; Green chemistry;	87%

...Expand

: 85-99-4
2-acetamidobenzophenone

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With hydrogenchloride In water at 125℃; for 3h;	86%
With hydrogenchloride
With hydrogenchloride In methanol; water at 60℃; for 3h; Schlenk technique; Inert atmosphere;	56.7 mg

: 85-99-4
2-acetamidobenzophenone

A: 5855-57-2
4-phenyl-2-quinolinone

B: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With sodium hydride In tetrahydrofuran for 2.5h; Heating;	A 83% B 16%
With sodium methylate In N,N-dimethyl-formamide at 100℃; for 3h; Reagent/catalyst; Solvent; Temperature; Schlenk technique; Inert atmosphere;
With potassium carbonate In tetrahydrofuran at 80℃; for 3h; Schlenk technique; Inert atmosphere;

: 615-43-0
2-iodophenylamine

: 98-80-6
phenylboronic acid

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With carbon monoxide; potassium carbonate In toluene at 120℃; under 22502.3 Torr; for 12h; Suzuki Coupling; Autoclave;	83%

: 93-98-1
N-phenyl benzoyl amide

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With zirconium(IV) oxychloride at 160 - 180℃; for 0.5h;	82%

: 615-43-0
2-iodophenylamine

: 82102-37-2
9-methyl-9H-fluorene-9-carbonyl chloride

: 98-80-6
phenylboronic acid

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
Stage #1: 9-methyl-9H-fluorene-9-carbonyl chloride With N-ethyl-N,N-diisopropylamine; bis(dibenzylideneacetone)-palladium(0); tri tert-butylphosphoniumtetrafluoroborate at 80℃; Stage #2: 2-iodophenylamine; phenylboronic acid With potassium carbonate; palladium dichloride at 80℃;	82%

...Expand

: 93-98-1
N-phenyl benzoyl amide

A: 1137-41-3
(4-aminophenyl)(phenyl)methanone

B: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
In water Irradiation; sodium dodecyl sulfate micelles;	A 15% B 80%
In methanol at 20 - 25℃; for 48h; Irradiation; Yield given;

: 484-38-8
isatic acid

: 98-80-6
phenylboronic acid

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With silver carbonate In acetonitrile at 60℃; for 1h;	80%

: 5100-23-2
2-isocyanatobenzoyl chloride

: 71-43-2
benzene

A: 71526-47-1
4,4-diphenyl-1,4-dihydro-3,1-benzoxazin-2(1H)-one

B: 91148-55-9
3-(2'-benzoylphenyl)-1,2,3,4-tetrahydroquinazoline-2,4-dione

C: 91148-57-1
3-(2'-benzoylphenyl)-4-(2'-benzoylphenylimino)-1,2,3,4-tetrahydroquinazoline-2-one

D: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With aluminium trichloride at 18 - 20℃; for 0.75h; Further byproducts given;	A 5% B 3% C 6% D 79%

...Expand

: 51674-05-6
1-(2-Aminophenyl)-1-phenyl-methanonoxim

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With cellulose supported Cu-nanoparticles In water at 100℃; for 0.133333h; Microwave irradiation; Green chemistry;	79%

: 3-(tert-butylperoxy)-3-phenylindolin-2-one

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With caesium carbonate In N,N-dimethyl-formamide at 0 - 23℃; for 12h; Inert atmosphere;	78%

: 7500-78-9
o-benzoylbenzamide

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
With sodium hypochlorite; sodium hydroxide In water at 85 - 90℃; Hofmann Rearrangement;	77.1%
With alkaline aqueous sodium hypochlorite solution
With ammonia; potassium amide; potassium nitrate
With sodium hydroxide; sodium hypobromide man versetzt die filtrierte Loesung mit Alkohol;

: 100-58-3
phenylmagnesium bromide

: 1885-29-6
anthranilic acid nitrile

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

Conditions

Conditions	Yield
Stage #1: phenylmagnesium bromide; anthranilic acid nitrile In tetrahydrofuran at 0 - 20℃; for 13h; Inert atmosphere; Stage #2: With hydrogenchloride In tetrahydrofuran; water at 0 - 20℃; for 12h; Inert atmosphere;	75%
Stage #1: phenylmagnesium bromide; anthranilic acid nitrile In diethyl ether at 0 - 20℃; Inert atmosphere; Stage #2: With hydrogenchloride; water In diethyl ether at 0 - 20℃; Inert atmosphere;	23.8%
Multi-step reaction with 2 steps 1: tetrahydrofuran / 20 h / 15 °C / Inert atmosphere 2: hydrogenchloride; water / 0.5 h / 60 °C / Inert atmosphere View Scheme
In tetrahydrofuran at 0 - 20℃; for 1.08333h; Inert atmosphere;
In tetrahydrofuran at 0 - 20℃;

: 108-24-7
acetic anhydride

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 85-99-4
2-acetamidobenzophenone

Conditions

Conditions	Yield
In dichloromethane at 20℃; Inert atmosphere;	100%
With pyridine	99%
With N,N'-diiodo-N,N'-1,2-ethanediylbis(p-toluenesulphonamide) at 80℃; for 0.166667h; neat (no solvent);	92%

: 123-54-6
acetylacetone

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 13337-57-0
3-acetyl-2-methyl-4-phenylquinoline

Conditions

Conditions	Yield
With 3-methyl-1-sulfoimidazolium trichloroacetate; trichloroacetic acid In neat (no solvent) at 100℃; Friedlaender Quinoline Synthesis;	100%
With sulfuric acid; silica gel at 100℃; for 0.75h; Friedlaender synthesis;	99%
With trifluoroacetic acid at 100℃; for 0.116667h;	99%

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 13209-38-6
(2-aminophenyl)(phenyl)methanol

Conditions

Conditions	Yield
With sodium tetrahydroborate In ethanol for 2h; Heating;	100%
With lithium aluminium tetrahydride In tetrahydrofuran at 0℃; for 1h; Reduction;	97%
With sodium tetrahydroborate In methanol at 0℃;	97%

: 598-21-0
2-Bromoacetyl bromide

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 14439-71-5
2'-benzoyl-2-bromo-acetanilide

Conditions

Conditions	Yield
	100%
With potassium carbonate In acetonitrile at 20℃; for 1h;	98%
With potassium carbonate In acetonitrile at 20℃; for 1h;	98%

: 762-21-0
acetylenedicarboxylic acid diethyl ester

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 17282-95-0
diethyl 4-phenylquinoline-2,3-dicarboxylate

Conditions

Conditions	Yield
With indium(III) chloride at 80℃; for 3h;	100%
With indium(III) chloride at 80℃; for 0.833333h; regioselective reaction;	94%
Stage #1: acetylenedicarboxylic acid diethyl ester With pyridine at 0 - 10℃; for 0.25h; Stage #2: (2-aminophenyl)(phenyl)methanone at 20℃; for 15h;	88%

: 504-02-9
1,3-cylohexanedione

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 17401-27-3
9-phenyl-3,4-dihydro-2H-acridin-1-one

Conditions

Conditions	Yield
With o-benzenedisulfonimide at 80℃; for 4h; Friedlaender synthesis; Neat (no solvent);	100%
With 3-methyl-1-sulfoimidazolium trichloroacetate; trichloroacetic acid In neat (no solvent) at 100℃; Friedlaender Quinoline Synthesis;	100%
With aluminum oxide In chloroform for 3h; Friedlaender reaction; Reflux;	98%

: 108-94-1
cyclohexanone

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 10265-83-5
9-phenyl-1,2,3,4-tetrahydroacridine

Conditions

Conditions	Yield
With o-benzenedisulfonimide at 80℃; for 6h; Friedlaender synthesis; Neat (no solvent);	100%
With citric acid at 100℃; for 4h; Friedlaender synthesis; neat (no solvent);	99%
With ammonium cerium (IV) nitrate In ethanol for 8h; Friedlaender synthesis; Reflux;	98%

: 126-81-8
dimedone

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 17282-85-8
3,3-dimethyl-9-phenyl-3,4-dihydro-2H-acridin-1-one

Conditions

Conditions	Yield
With 3-methyl-1-sulfoimidazolium trichloroacetate; trichloroacetic acid In neat (no solvent) at 100℃; Friedlaender Quinoline Synthesis;	100%
scandium tris(dodecyl sulfate) In water at 40℃; Friedlaender annulation;	99%
With aluminum oxide In chloroform for 3h; Friedlaender reaction; Reflux;	98%

: 536-74-3
phenylacetylene

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 1-(2-aminophenyl)-1,3-diphenylprop-2-yn-1-ol

Conditions

Conditions	Yield
With potassium tert-butylate In neat (no solvent) at 20℃; for 2h; Inert atmosphere; Green chemistry;	100%
Stage #1: phenylacetylene With ethylmagnesium bromide In tetrahydrofuran at 50℃; for 2h; Stage #2: (2-aminophenyl)(phenyl)methanone In tetrahydrofuran at 50℃; Further stages.;
Stage #1: phenylacetylene With ethyl bromide; magnesium In tetrahydrofuran at 0 - 50℃; Inert atmosphere; Reflux; Stage #2: (2-aminophenyl)(phenyl)methanone In tetrahydrofuran at 50℃; Inert atmosphere; Stage #3: With ammonium chloride In tetrahydrofuran Saturated solution;
With potassium tert-butylate In neat (no solvent) at 20℃; for 2h; Inert atmosphere;
With potassium tert-butylate at 20℃; for 2h; Inert atmosphere;

: 103-80-0
phenylacetyl chloride

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 342603-80-9
N-(2-benzoylphenyl)-2-phenylacetamide

Conditions

Conditions	Yield
With pyridine In dichloromethane for 3h;	100%

: 15761-39-4
1-(tert-butoxycarbonyl)-L-proline

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 1093987-00-8
(S)-tert-butyl 2-{[(2-benzoylphenyl)amino]carbonyl}pyrrolidine-1-carboxylate

Conditions

Conditions	Yield
With triethylamine; isobutyl chloroformate In tetrahydrofuran at 0℃;	100%
Stage #1: 1-(tert-butoxycarbonyl)-L-proline With triethylamine; isobutyl chloroformate In tetrahydrofuran at 0℃; for 1h; Inert atmosphere; Stage #2: (2-aminophenyl)(phenyl)methanone In tetrahydrofuran at 0 - 20℃; Inert atmosphere;	100%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20 - 55℃; for 12h; Reagent/catalyst;	97%
Stage #1: 1-(tert-butoxycarbonyl)-L-proline With 1-methyl-1H-imidazole; methanesulfonyl chloride In dichloromethane at 25℃; for 0.166667h; Stage #2: (2-aminophenyl)(phenyl)methanone In dichloromethane at 50℃; for 36h;	91%
Stage #1: 1-(tert-butoxycarbonyl)-L-proline With 4-methyl-morpholine; isobutyl chloroformate In tetrahydrofuran at -5 - 25℃; Large scale; Stage #2: (2-aminophenyl)(phenyl)methanone In tetrahydrofuran at 20 - 25℃; Large scale;	75%

: 124676-19-3
2-(benzotriazol-1-yl)-N-(benzyloxycarbonyl)glycine

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 108895-97-2
2-

Conditions

Conditions	Yield
Stage #1: 2-(benzotriazol-1-yl)-N-(benzyloxycarbonyl)glycine With oxalyl dichloride; N,N-dimethyl-formamide In tetrahydrofuran at 0℃; for 0.25h; Inert atmosphere; Stage #2: (2-aminophenyl)(phenyl)methanone With 4-methyl-morpholine In tetrahydrofuran at 0℃; for 0.5h; Inert atmosphere; Stage #3: With ammonia In tetrahydrofuran at 0 - 20℃; for 17h; Inert atmosphere;	100%

: 128-08-5
N-Bromosuccinimide

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 39859-36-4
2-amino-5-bromobenzophenone

Conditions

Conditions	Yield
In dichloromethane at 0 - 20℃;	100%

: 860800-19-7
9H-fluoren-9-ylmethyl N-[(1S)-1-benzyl-2-benzotriazol-1-yl-2-oxoethyl]carbamate

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: C37H30N2O4

Conditions

Conditions	Yield
With trifluoroacetic acid In toluene for 3h; Solvent;	100%

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 28059-64-5
2-benzylaniline

Conditions

Conditions	Yield
With potassium hydroxide In water at 50℃; for 4h; Reagent/catalyst; Temperature;	99.5%
With sodium In ethanol	90%
With ethoxyethoxyethanol; hydrazine hydrate; potassium hydroxide at 200℃; under 10343.2 Torr; Wolff-Kishner Reduction; Sonication;	82%

: 501-65-5
diphenyl acetylene

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 10380-73-1
2,3,4-triphenyl quinoline

Conditions

Conditions	Yield
With 18-crown-6 ether; trifluorormethanesulfonic acid; palladium diacetate; 1,2-bis-(diphenylphosphino)ethane In toluene; acetonitrile at 105℃; for 11h; Reagent/catalyst; Solvent; Sealed tube;	99.1%
With palladium(II) bromide; Trimethylacetic acid In benzonitrile; 1,2-dichloro-ethane at 130℃; for 18h; Reagent/catalyst; Solvent; Temperature; Sealed tube;	83%

: 98-88-4
benzoyl chloride

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 29670-64-2
N-(2-benzoylphenyl)benzamide

Conditions

Conditions	Yield
With pyridine In dichloromethane at 20℃; for 3h;	99%
With pyridine In dichloromethane Ambient temperature;	94%
In dichloromethane at 20℃; for 1h;	85%
With pyridine
With triethylamine In dichloromethane for 4h;

: 124676-19-3
2-(benzotriazol-1-yl)-N-(benzyloxycarbonyl)glycine

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 161365-74-8
benzyl N-[[(2-benzoylphenyl)carbamoyl](1H-1,2,3-benzotriazol-1-yl)methyl]carbamate

Conditions

Conditions	Yield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃;	99%
Stage #1: 2-(benzotriazol-1-yl)-N-(benzyloxycarbonyl)glycine With oxalyl dichloride; N,N-dimethyl-formamide In tetrahydrofuran at 0℃; for 2h; Stage #2: (2-aminophenyl)(phenyl)methanone With 4-methyl-morpholine In tetrahydrofuran at 0 - 20℃; for 0.5h;	87%
With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide at 0 - 25℃;
With dmap; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide In dichloromethane at 0 - 20℃;
Stage #1: 2-(benzotriazol-1-yl)-N-(benzyloxycarbonyl)glycine With oxalyl dichloride In tetrahydrofuran; N,N-dimethyl-formamide at 0℃; for 2h; Stage #2: (2-aminophenyl)(phenyl)methanone With 4-methyl-morpholine In tetrahydrofuran; N,N-dimethyl-formamide at 0 - 20℃; for 0.5h;

: 536-74-3
phenylacetylene

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 1039-51-6
2,4-diphenylquinoline

Conditions

Conditions	Yield
With tetrafluoroboric acid; water; dodecacarbonyl-triangulo-triruthenium In toluene at 160℃; for 12h; Addition; Hydroamination;	99%
With potassium dodeca tungstocobaltate trihydrate at 110℃; for 0.25h; Microwave irradiation; neat (no solvent);	95%
With indium(III) chloride In acetonitrile for 3h; Reflux; regioselective reaction;	93%

: 6781-42-6
1,3-diacetylbenzene

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 321882-19-3
1,3-bis(4'-phenyl-2'-quinolinyl)benzene

Conditions

Conditions	Yield
With phosphorus pentaoxide; 3-methyl-phenol at 135℃; Friedlaender reaction;	99%

: 141-97-9
ethyl acetoacetate

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 313273-62-0
3-acetyl-4-phenyl-1,2-dihydroquinolin-2-one

Conditions

Conditions	Yield
With zeolitic imidazolate framework-8 catalyst In toluene at 90℃; for 24h; Friedlaender Quinoline Synthesis;	99%
With SBA-15/AP mesoporous materials at 89.84℃; for 6h; Friedlaender synthesis; neat (no solvent);	96%
With Amberlite Na sr1L at 115℃; for 0.0833333h; Microwave irradiation; Neat (no solvent);	90.2%

: 120-92-3
cyclopentanone

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 10265-82-4
9-phenyl-2,3-dihydro-1H-cyclopenta[b]quinoline

Conditions

Conditions	Yield
With acetic acid at 160℃; for 0.0833333h; Friedlaender Quinoline Synthesis; Microwave irradiation;	99%
With ammonium cerium (IV) nitrate In ethanol for 6h; Friedlaender synthesis; Reflux;	98%
With 3-methyl-1-sulfoimidazolium trichloroacetate; trichloroacetic acid In neat (no solvent) at 100℃; Friedlaender Quinoline Synthesis;	97%

: 105-45-3
acetoacetic acid methyl ester

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: methyl 2-methyl-4-phenylquinoline-3-carboxylate

Conditions

Conditions	Yield
scandium tris(dodecyl sulfate) In water at 40℃; Friedlaender annulation;	99%
With 3-methyl-1-sulfoimidazolium trichloroacetate; trichloroacetic acid In neat (no solvent) at 100℃; Friedlaender Quinoline Synthesis;	98%
With magnetic Fe-Cr-Ni oxide alloy nano-belts In water at 20℃; for 0.583333h;	98%

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 39859-36-4
2-amino-5-bromobenzophenone

Conditions

Conditions	Yield
With N-Bromosuccinimide In dichloromethane at 0 - 20℃; for 3h;	99%
With sodium perborate; ammonium molybdate(VI) tetrahydrate; potassium bromide In acetic acid at 0℃; for 3h;	96%
With sodium perborate; ammonium molibdate; potassium bromide In acetic acid at 0℃; for 3h;	96%

: 98-85-1, 13323-81-4
1-Phenylethanol

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 1039-51-6
2,4-diphenylquinoline

Conditions

Conditions	Yield
With benzophenone; dichlorotetrakis(dimethyl sulfoxide)ruthenium(II); potassium tert-butylate at 100℃; for 48h; indirect Friedlaender annulation;	99%
With potassium hydroxide at 80℃; for 7h; Friedlaender Quinoline Synthesis;	83%

: 1737-26-4
1-(4-trifluorophenyl)ethanol

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 4-phenyl-2-(4-(trifluoromethyl)phenyl)quinoline

Conditions

Conditions	Yield
With benzophenone; dichlorotetrakis(dimethyl sulfoxide)ruthenium(II); potassium tert-butylate at 100℃; for 48h; indirect Friedlaender annulation;	99%

: 29943-42-8
Tetrahydro-4H-pyran-4-one

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 17517-75-8
10-phenyl-3,4-dihydro-1H-pyrano[4,3-b]quinoline

Conditions

Conditions	Yield
With acetic acid at 160℃; for 0.0833333h; Friedlaender Quinoline Synthesis; Microwave irradiation;	99%
With magnesium chloride hexahydrate; toluene-4-sulfonic acid In acetonitrile at 50℃; for 0.666667h; Friedlaender synthesis;	94%
With lithium bromide In acetonitrile at 50℃; for 1.5h; Friedlaender heteroannulation;	80%

: 141-97-9
ethyl acetoacetate

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 109-77-3
malononitrile

: 1235990-71-2
6-amino-4-(2-aminophenyl)-2,4-dihydro-3-methyl-4-phenylpyrano[2,3-c]pyrazole-5-carbonitrile

Conditions

Conditions	Yield
With hydrazine hydrate; heptakis(6-amino-6-deoxy)-β-cyclodextrin at 20℃; for 0.0166667h; Neat (no solvent);	99%

...Expand

: 127-19-5
N,N-dimethyl acetamide

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 17629-01-5
4-phenylquinazoline

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; N-iodo-succinimide; ammonia In water at 120℃; for 4h;	99%
With ammonium acetate; oxygen; acetic acid; copper(l) chloride at 110℃; under 760.051 Torr; for 12h; Schlenk technique; Green chemistry;	82%

2-Aminobenzophenone Specification

The Methanone,(2-aminophenyl)phenyl-, with the CAS registry number 2835-77-0, is also known as 2-Aminobenzophenone. It belongs to the product categories of Fine Chemical & Intermediates; Aromatic Benzophenones & Derivatives (substituted). Its EINECS registry number is 220-613-9. This chemical's molecular formula is C₁₃H₁₁NO and molecular weight is 197.23254. Its IUPAC name is called (2-aminophenyl)-phenylmethanone. What's more, the product should be sealed and stored in cool and dry place.

Physical properties of Methanone,(2-aminophenyl)phenyl-: (1)ACD/LogP: 2.50; (2)ACD/LogD (pH 5.5): 2.5; (3)ACD/LogD (pH 7.4): 2.5; (4)ACD/BCF (pH 5.5): 46.61; (5)ACD/BCF (pH 7.4): 46.61; (6)ACD/KOC (pH 5.5): 544.37; (7)ACD/KOC (pH 7.4): 544.37; (8)#H bond acceptors: 2; (9)#H bond donors: 2; (10)#Freely Rotating Bonds: 3; (11)Index of Refraction: 1.628; (12)Molar Refractivity: 60.28 cm³; (13)Molar Volume: 169.8 cm³; (14)Surface Tension: 50.5 dyne/cm; (15)Density: 1.161 g/cm³; (16)Flash Point: 185.9 °C; (17)Enthalpy of Vaporization: 63.23 kJ/mol; (18)Boiling Point: 383.7 °C at 760 mmHg; (19)Vapour Pressure: 4.31E-06 mmHg at 25°C.

Uses of Methanone,(2-aminophenyl)phenyl-: it can be used to produce 3-phenyl-benzo[c]isoxazole. This reaction will need reagent sulfate sulfomonoperoxoic acid.

Methanone,(2-aminophenyl)phenyl- can be used to produce 3-phenyl-benzo[c]isoxazole

When you are using this chemical, please be cautious about it as the following:
This chemical may cause inflammation to the skin or other mucous membranes and may cause damage to health. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. Whenever you will contact it, please wear suitable protective clothing, gloves and eye/face protection.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C1=CC=C(C=C1)C(=O)C2=CC=CC=C2N
(2)InChI: InChI=1S/C13H11NO/c14-12-9-5-4-8-11(12)13(15)10-6-2-1-3-7-10/h1-9H,14H2
(3)InChIKey: MAOBFOXLCJIFLV-UHFFFAOYSA-N

Product Name

2-Aminobenzophenone

Synthetic route

2-Aminobenzophenone Specification

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