2-iodobenzyl alcohol
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With manganese(IV) oxide In chloroform at 20℃; for 70h; | 99% |
With 1-methyl-1H-imidazole; tetrakis(acetonitrile)copper(I) trifluoromethanesulfonate; 4,4'-Dimethoxy-2,2'-bipyridin; 9-azabicyclo[3.3.1]nonane N-oxyl; oxygen In acetonitrile at 20℃; for 1h; | 98% |
With silica gel; pyridinium chlorochromate In dichloromethane at 20℃; Inert atmosphere; | 98% |
ortho-bromobenzaldehyde
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With copper(l) iodide; Trimethylenediamine; sodium iodide In 1,4-dioxane for 24h; Finkelstein Reaction; Reflux; Inert atmosphere; | 99% |
Multi-step reaction with 3 steps 1: 83 percent / TsOH / 5 h / Heating 2: 1.) Grignard reagent, 2.) I2 / 1.), 2.) THF 3: 83 percent / aq. HCl / tetrahydrofuran / 20 h / Ambient temperature View Scheme | |
With copper(l) iodide; sodium iodide; N,N`-dimethylethylenediamine In 1,4-dioxane at 120℃; under 1500.15 Torr; for 24h; Reagent/catalyst; Finkelstein Reaction; Autoclave; Inert atmosphere; Schlenk technique; |
(2-iodophenyl)methyl acetate
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With methanol; potassium permanganate In ethyl acetate at 25℃; for 14h; | 98% |
Multi-step reaction with 2 steps 1: aqueous KOH 2: AgNO3; Na2S2O8; water View Scheme |
2-bromobenzaldehyde diethyl acetal
2-iodobenzaldehyde
Conditions | Yield |
---|---|
Stage #1: 2-bromobenzaldehyde diethyl acetal With n-butyllithium In tetrahydrofuran; hexane at -78 - -10℃; for 1.41667h; Stage #2: With iodine In tetrahydrofuran; hexane at -78 - 20℃; for 12.6667h; | 98% |
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With Iodine monochloride In dichloromethane at 20℃; for 2h; Inert atmosphere; | 94% |
2-Iodobenzoic acid
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With manganese(IV) oxide; borane-THF Inert atmosphere; | 90% |
Multi-step reaction with 2 steps 1: 40 percent / HCl / 30 h / Heating 2: 34 percent / diisobutylaluminum hydride / toluene / 2 h / -60 °C View Scheme | |
Multi-step reaction with 2 steps 1: 67 percent / SOCl2, DMF / 2 h / Heating 2: tert-butyl alcohol, LiAlH4 / bis-(2-methoxy-ethyl) ether / -78 - 20 °C View Scheme |
2-Iodo-N-methyl-N-phenylbenzamide
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With zirconocene dichloride; lithium tri-t-butoxyaluminum hydride In tetrahydrofuran at 20℃; for 0.116667h; Inert atmosphere; | 90% |
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With Iodine monochloride In dichloromethane at 20℃; for 2h; Inert atmosphere; | 90% |
Multi-step reaction with 2 steps 1: acetonitrile / 10 h / 20 °C / pH 5 2: Iodine monochloride / dichloromethane / 2 h / 20 °C / Inert atmosphere View Scheme |
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With Iodine monochloride In dichloromethane at 20℃; for 2h; Inert atmosphere; | 89% |
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With Iodine monochloride In dichloromethane at 20℃; for 2h; Inert atmosphere; | 85% |
Multi-step reaction with 2 steps 1: acetonitrile / 10 h / 20 °C / pH 5 2: Iodine monochloride / dichloromethane / 2 h / 20 °C / Inert atmosphere View Scheme |
2-iodobenzaldehyde ethylene glycol ketal
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With hydrogenchloride In tetrahydrofuran for 20h; Ambient temperature; | 83% |
2-formylbenzene boronic acid
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With perfluoroisopropyl iodide; copper; hydroquinone In N,N-dimethyl-formamide at 20℃; for 24h; | 83% |
2-iodo-N-methoxy-N-methyl-benzamide
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With diisobutylaluminium hydride In tetrahydrofuran; hexane at -78℃; for 2h; Inert atmosphere; | 77% |
C13H20IN
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With [bis(acetoxy)iodo]benzene; sodium hydrogencarbonate In chloroform at 60℃; for 2h; Polonovski type reaction; | 75% |
2-(2'-formylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With copper(I) oxide; 1,10-Phenanthroline; potassium iodide In methanol; water at 80℃; for 1h; High pressure; | 70% |
With copper(I) oxide; 1,10-Phenanthroline; potassium iodide In methanol; water at 80℃; for 1h; Sealed tube; | 65% |
o-iodo-methyl-benzoic acid
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With diisobutylaluminium hydride In toluene at -60℃; for 2h; | 34% |
ortho-methylphenyl iodide
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With sulfuric acid bei der elektrolytischen Oxydation; | |
Multi-step reaction with 4 steps 1: tetrachloromethane; dibenzoyl peroxide; N-bromo-succinimide 2: acetic acid 3: aqueous KOH 4: AgNO3; Na2S2O8; water View Scheme |
2-iodobenzonitrile
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With hydrogenchloride; diethyl ether; tin(ll) chloride anschl. mit H2O; |
2-Iodobenzyl bromide
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With chloroform; hexamethylenetetramine Erhitzen des Reaktionsprodukts mit wss. Essigsaeure; | |
Multi-step reaction with 3 steps 1: acetic acid 2: aqueous KOH 3: AgNO3; Na2S2O8; water View Scheme |
benodanil
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With phosphorus pentachloride; toluene at 100℃; Erwaermen des Reaktionsprodukts mit SnCl2 und aether. HCl und anschliessendes Behandeln mit Wasser; |
2-Iodobenzoyl chloride
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With tetrahydrogenoboratebis(triphenylphosphine)copper(I); triphenylphosphine In acetone for 1h; | 17.2 g |
Multi-step reaction with 2 steps 1: 98 percent / sodium borohydride / dioxane / 1 h / steam-bath 2: 76.4 percent / pyridinium dichromate / CH2Cl2 / 3 h / Ambient temperature View Scheme | |
Multi-step reaction with 2 steps 2: toluene; PCl5 / 100 °C / Erwaermen des Reaktionsprodukts mit SnCl2 und aether. HCl und anschliessendes Behandeln mit Wasser View Scheme |
2-iodobenzylamine
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With N-bromoacetamide In water at 14.9 - 34.9℃; Kinetics; Thermodynamic data; ΔH(excit.), ΔS(excit.); |
2-iodobenzaldehyde
Conditions | Yield |
---|---|
In acetic acid at 19.9℃; Rate constant; Kinetics; Thermodynamic data; ΔH(excit.), ΔS(excit.), ΔG(excit.), var. temp.; |
Conditions | Yield |
---|---|
With lithium aluminium tetrahydride; tert-butyl alcohol In diethylene glycol dimethyl ether at -78 - 20℃; Yield given. Yields of byproduct given. Title compound not separated from byproducts; |
ortho-methylphenyl iodide
sulfuric acid
A
2-Iodobenzoic acid
B
2-iodobenzaldehyde
Conditions | Yield |
---|---|
bei der elektrolytischen Oxydation; |
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With potassium iodide | |
With potassium iodide |
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With potassium permanganate |
(2-iodo-benzylidene)-malonic acid
water
A
malonic acid
B
carbon dioxide
C
2-iodobenzaldehyde
D
(E)-3-(2-Iodophenyl)propenoic acid
2-(2-bromophenyl)-1,3-dioxolan
2-iodobenzaldehyde
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 1.) Grignard reagent, 2.) I2 / 1.), 2.) THF 2: 83 percent / aq. HCl / tetrahydrofuran / 20 h / Ambient temperature View Scheme |
2-iodobenzaldehyde
2-(3,4-dimethoxyphenyl)-ethylamine
2-iodobenzaldehyde
phenylhydrazine
2-iodo-benzaldehyde phenylhydrazone
Conditions | Yield |
---|---|
In 1-methyl-pyrrolidin-2-one at 160℃; for 0.166667h; microwave irradiation; | 100% |
2-iodobenzaldehyde
N-methylhydroxyamine hydrochloride
(Z)-N-(2-iodobenzylidene)methylamine N-oxide
Conditions | Yield |
---|---|
With sodium hydrogencarbonate at 20℃; for 2h; | 100% |
2-iodobenzaldehyde
glycine ethyl ester hydrochloride
methyl 2-[N-(2-iodobenzyl)amino]acetate
Conditions | Yield |
---|---|
With sodium tris(acetoxy)borohydride; acetic acid; triethylamine In dichloromethane at 20℃; for 19h; Inert atmosphere; | 100% |
2-iodobenzaldehyde
glycine ethyl ester hydrochloride
Conditions | Yield |
---|---|
With sodium tris(acetoxy)borohydride; acetic acid; triethylamine In dichloromethane at 20℃; for 19h; Inert atmosphere; | 100% |
2-iodobenzaldehyde
methoxymethyltriphenylphosphonium bromide
Conditions | Yield |
---|---|
Stage #1: methoxymethyltriphenylphosphonium bromide With potassium tert-butylate In tetrahydrofuran at 0℃; for 0.25h; Inert atmosphere; Stage #2: 2-iodobenzaldehyde In tetrahydrofuran at 20℃; for 3h; Inert atmosphere; | 100% |
2-Methoxypropene
2-iodobenzaldehyde
Conditions | Yield |
---|---|
With silica gel; acetic acid; tris(6,6,7,7,8,8,8-heptafluoro-2,2-dimethyl-3,5-octanedionato)ytterbium In dichloromethane at 25℃; Addition; | 99% |
With tris(6,6,7,7,8,8,8-heptafluoro-2,2-dimethyl-3,5-octanedionato)ytterbium; silica gel; acetic acid at 25℃; | 97% |
2-iodobenzaldehyde
2-Iodobenzoic acid
Conditions | Yield |
---|---|
With potassium permanganate; tetrabutylammomium bromide; water In dichloromethane; acetone at 20℃; for 24h; | 99% |
With perchloric acid; N-Chlorourethan; acetic acid In water at 29.9℃; for 10h; Rate constant; Kinetics; Thermodynamic data; ΔH(excit.), ΔS(excit.), ΔG(excit.); | |
With perchloric acid; mercury(II) diacetate; N-bromoacetamide In acetic acid at 24.9℃; Kinetics; Mechanism; Thermodynamic data; other temperatures, ΔG(excit.), ΔH(excit.), ΔS(excit.); |
Conditions | Yield |
---|---|
With potassium carbonate In water at 20℃; for 0.5h; Suzuki-Miyaura Coupling; | 99% |
With potassium carbonate In ethanol; water at 20℃; for 1h; Suzuki-Miyaura Coupling; Green chemistry; | 94% |
With potassium phosphate In 1,4-dioxane at 70℃; for 1.5h; Suzuki-Miyaura Coupling; | 93% |
Cyclohexyl isocyanide
2-iodobenzaldehyde
acetic acid
N-butylamine
Conditions | Yield |
---|---|
In methanol at 20℃; Ugi reaction; | 99% |
2-iodobenzaldehyde
isocyanoacetic acid methyl ester
acetic acid
GlyOEt*HCl
Conditions | Yield |
---|---|
In methanol at 20℃; Ugi reaction; | 99% |
Conditions | Yield |
---|---|
Stage #1: (2-iodobenzyl)triphenylphosphonium bromide With potassium tert-butylate In tetrahydrofuran at 0℃; Stage #2: 2-iodobenzaldehyde In tetrahydrofuran at 20℃; Wittig reaction; Further stages.; | 99% |
With potassium hydroxide In chloroform; water at 20℃; for 2.5h; Reflux; | 92% |
4-Octyne
2-iodobenzaldehyde
1-amino-naphthalene
N-(2,3-dipropyl-1H-inden-1-yl)naphthalen-1-amine
Conditions | Yield |
---|---|
With Co(dppe)Cl2; zinc In tetrahydrofuran; acetonitrile at 120℃; for 12h; Inert atmosphere; regioselective reaction; | 99% |
4-Octyne
2-iodobenzaldehyde
p-toluidine
2,3-dipropyl-N-p-tolyl-1H-inden-1-amine
Conditions | Yield |
---|---|
With Co(dppe)Cl2; zinc In tetrahydrofuran; acetonitrile at 120℃; for 12h; Inert atmosphere; regioselective reaction; | 99% |
2,2-dimethyl-3-butyne
2-iodobenzaldehyde
Conditions | Yield |
---|---|
Stage #1: 3,3-Dimethylbut-1-yne With n-butyllithium In tetrahydrofuran at -78℃; for 0.5h; Stage #2: 2-iodobenzaldehyde In tetrahydrofuran at 20℃; for 3h; | 99% |
Stage #1: 3,3-Dimethylbut-1-yne With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 0.5h; Inert atmosphere; Stage #2: 2-iodobenzaldehyde In tetrahydrofuran; hexane at 20℃; for 4h; Stage #3: With ammonium chloride In tetrahydrofuran; hexane; water |
2-iodobenzaldehyde
phenylmagnesium bromide
(2-iodophenyl)(phenyl)methanol
Conditions | Yield |
---|---|
In diethyl ether at 0 - 20℃; for 1h; Inert atmosphere; | 99% |
diethoxyphosphoryl-acetic acid ethyl ester
2-iodobenzaldehyde
ethyl 3-(2-iodophenyl)acrylate
Conditions | Yield |
---|---|
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.5h; Stage #2: 2-iodobenzaldehyde In tetrahydrofuran at 0 - 20℃; for 2h; | 99% |
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran; mineral oil at 0℃; for 0.5h; Horner-Wadsworth-Emmons Olefination; Inert atmosphere; Stage #2: 2-iodobenzaldehyde In tetrahydrofuran; mineral oil at 0 - 20℃; Horner-Wadsworth-Emmons Olefination; Inert atmosphere; | 85% |
diethoxyphosphoryl-acetic acid ethyl ester
2-iodobenzaldehyde
ethyl (E)-3-(2-iodophenyl)-2-propenoate
Conditions | Yield |
---|---|
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In dichloromethane at 0℃; for 0.0833333h; Wittig-Horner reaction; Stage #2: 2-iodobenzaldehyde In dichloromethane at 0℃; for 0.5h; Wittig-Horner reaction; Further stages.; | 98.7% |
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In tetrahydrofuran Stage #2: 2-iodobenzaldehyde In tetrahydrofuran at 20℃; | 92% |
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In dichloromethane; mineral oil at 0℃; for 0.0833333h; Inert atmosphere; Stage #2: 2-iodobenzaldehyde In dichloromethane; mineral oil at 0℃; for 2h; Inert atmosphere; | 89% |
2-iodobenzaldehyde
Biphenyl-2,2'-dicarbaldehyde
Conditions | Yield |
---|---|
With copper(I) thiophene-2-carboxylate; copper In dimethyl sulfoxide at 65℃; Ullmann Condensation; | 98% |
With indium; palladium 10% on activated carbon; tetrabutylammomium bromide; lithium chloride In water at 90℃; for 24h; Green chemistry; | 75% |
With palladium diacetate; potassium carbonate In N,N-dimethyl-formamide at 100℃; for 24h; | 64% |
2-iodobenzaldehyde
acetylenemagnesium bromide
1-(2-iodophenyl)prop-2-yn-1-ol
Conditions | Yield |
---|---|
In tetrahydrofuran at 0℃; for 2.5h; Inert atmosphere; Sealed tube; | 98% |
In tetrahydrofuran for 2h; Ambient temperature; | 95% |
In tetrahydrofuran at -60℃; for 14h; | 86% |
In tetrahydrofuran at 0℃; Inert atmosphere; |
2-iodobenzaldehyde
N-tosyl-N-allylpropargylamine
N-allyl-N-(3-(2-formylphenyl)prop-2-yn-1-yl)-4-methylbenzenesulfonamide
Conditions | Yield |
---|---|
Stage #1: 2-iodobenzaldehyde With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine for 0.166667h; Inert atmosphere; Stage #2: N-tosyl-N-allylpropargylamine Inert atmosphere; | 98% |
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; potassium carbonate In tetrahydrofuran at 50℃; for 6h; Sonogashira coupling; | |
With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine Inert atmosphere; |
4-Octyne
2-iodobenzaldehyde
3,5-difluoroaniline
N-(3,5-difluorophenyl)-2,3-dipropyl-1H-inden-1-amine
Conditions | Yield |
---|---|
With Co(dppe)Cl2; zinc In tetrahydrofuran; acetonitrile at 120℃; for 12h; Inert atmosphere; regioselective reaction; | 98% |
2-iodobenzaldehyde
3-(p-tolylamino)-5,5-dimethylcyclohex-2-enone
9-(4,4-dimethyl-6-oxo-2-(p-tolylamino)cyclohex-1-enyl)-3,3-dimethyl-10-(p-tolyl)-3,4,9,10-tetrahydroacridin-1(2H)-one
Conditions | Yield |
---|---|
With 1,4-diaza-bicyclo[2.2.2]octane; palladium diacetate; caesium carbonate In toluene at 110℃; for 12h; | 98% |
With caesium carbonate In toluene at 110℃; for 24h; Inert atmosphere; | 86% |
2-iodobenzaldehyde
tri(naphthalen-1-yl)bismuth
2-(naphthalene-1-yl)benzaldehyde
Conditions | Yield |
---|---|
With potassium phosphate; copper(l) iodide; palladium diacetate; triphenylphosphine In N,N-dimethyl-formamide at 90℃; for 3h; | 98% |
Conditions | Yield |
---|---|
With silver(I) acetate; copper diacetate; ethoxy(potassiosulfanyl)methanethione In N,N-dimethyl-formamide at 100℃; for 5h; | 98% |
1-ethynyl-4-fluorobenzene
2-iodobenzaldehyde
3-(4-fluorophenyl)isoquinoline
Conditions | Yield |
---|---|
With 1,2-bis(diphenylphosphino)ethane nickel(II) chloride; triethylamine In acetonitrile at 20℃; for 12h; Inert atmosphere; Schlenk technique; regioselective reaction; | 98% |
Molecular Formula: C7H5IO
Molar mass: 232.02 g/mol
Density: 1.883 g/cm3
Flash Point: 114.8 °C
Index of Refraction: 1.668
Melting point: 36-39 °C(lit.)
Sensitive: Light Sensitive
Boiling Point: 266.3 °C at 760 mmHg
Vapour Pressure: 0.00873 mmHg at 25°C
Appearance: White to light beige low melting crystalline
Structure of 2-Iodobenzaldehyde (26260-02-6) :
Product Categories of 2-Methyl-3-nitropyridine hydrochloride (63585-69-3) : Aldehydes;Benzaldehyde;Carbonyl Compounds;Iodine Compounds;Phenyls & Phenyl-Het;Aromatic Aldehydes & Derivatives (substituted);Adehydes, Acetals & Ketones
Carcinogenicity of 2-Iodobenzaldehyde (26260-02-6) hasn't been listed as a carcinogen by NTP, IARC,ACGIH, or CA Prop 65. And its toxicological properties have not been fully investigated.
Hazard Codes:Xi
Risk Statements:
36: Irritating to the eyes
37: Irritating to the respiratory system
38: Irritating to the skin
Safety Statements:
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
37: Wear suitable gloves
39: Wear eye/face protection
2-Iodobenzaldehyde (26260-02-6) is a compound which also can be called for benzaldehyde, 2-iodo- . 2-Iodobenzaldehyde (26260-02-6) is hazardous,so the first aid measures and others should be known .Such as: When on the skin: first,should flush skin with plenty of water immediatelyfor at least 15 minutes while removing contaminated clothing.Secondly,Get shoesmedical aid . Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.Then get medical aid soon.While ,it's Inhaled: Remove from exposure and move to fresh air immediately.Give artificial respiration While not breathing. when breathing is difficult, give oxygen.And as soon as to get medical aid.Then you have the ingesting of the product : Wash mouth out with water,and get medical aid immediately.Notes to Physician: Treat supportively and symptomatically.
In addition, 2-Iodobenzaldehyde (26260-02-6) can be stable under normal temperature and pressure conditions.It is not compatible with strong oxidizing agents and you must not take it with incompatible materials.And also prevent it to broken down into hazardous decomposition products: carbon dioxide,hydrogen iodide,carbon monoxide.
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