Product Name

  • Name

    11 -Hydroxy-2-phenylbenzene

  • EINECS 201-993-5
  • CAS No. 90-43-7
  • Article Data265
  • CAS DataBase
  • Density 1.111 g/cm3
  • Solubility 0.7 g/L (20 °C) in water
  • Melting Point 57-59 °C(lit.)
  • Formula C12H10O
  • Boiling Point 282 °C at 760 mmHg
  • Molecular Weight 170.211
  • Flash Point 140.3 °C
  • Transport Information UN 3077 9/PG 3
  • Appearance Off-white powder
  • Safety 22-61
  • Risk Codes 36/37/38-50-37/38/50-36
  • Molecular Structure Molecular Structure of 90-43-7 (11 -Hydroxy-2-phenylbenzene)
  • Hazard Symbols IrritantXi, DangerousN
  • Synonyms 1,1'-Biphenyl-2-ol;2-Biphenylol;2-Hydroxybiphenyl;2-hydroxydiphenyl;
  • PSA 20.23000
  • LogP 3.05920

Synthetic route

2-methoxy-1,1'-biphenyl
86-26-0

2-methoxy-1,1'-biphenyl

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
With boron tribromide In dichloromethane at 0 - 25℃;100%
With boron tribromide In dichloromethane at -80℃;
(RS)-2-phenylcyclohexanone
1444-65-1

(RS)-2-phenylcyclohexanone

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
With palladium chloride*2MeCN; chloranil In 1,4-dioxane at 100℃; for 18h;100%
Multi-step reaction with 2 steps
1: dimethyl sulfoxide; oxygen; palladium(II) trifluoroacetate / acetic acid / 12 h / 80 °C / Reflux; Sealed tube
2: dimethyl sulfoxide; iodine / nitromethane / 24 h / 100 °C / Sealed tube; Green chemistry
View Scheme
2-Iodophenol
533-58-4

2-Iodophenol

phenylboronic acid
98-80-6

phenylboronic acid

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
With potassium phosphate; SBA-Si-PEG-Pd(PPh3)n In water at 50℃; for 10h; Suzuki coupling;99%
With palladium 10% on activated carbon; potassium carbonate In water at 20 - 80℃; for 18.5h; Suzuki-Miyaura Coupling; Inert atmosphere;97%
With bis(1,1'-ethylene-3,3'-divinylimidazole-2,2'-diylidene)nickel(II) dibromide dihydrate; potassium carbonate In water; N,N-dimethyl-formamide at 100℃; for 8h; Suzuki-Miyaura Coupling; Inert atmosphere; Schlenk technique;96%
6-tert-butyl-6-phenyl-6H-dibenzo[c,e][1,2]oxasiline
1178513-84-2

6-tert-butyl-6-phenyl-6H-dibenzo[c,e][1,2]oxasiline

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 70℃; for 5h;99%
trimethyl(biphenyl-2-yloxy)silane
1022-21-5

trimethyl(biphenyl-2-yloxy)silane

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
With methanol; 1,3-disulfonic acid imidazolium hydrogen sulfate at 20℃; for 0.0666667h; Green chemistry;99%
2-Biphenylboronic acid
4688-76-0

2-Biphenylboronic acid

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
With oxygen; N-ethyl-N,N-diisopropylamine; [5,6]fullerene-C70 In chloroform; toluene at 20℃; for 12h; Irradiation;98%
With N,N-dimethyl-p-toluidine N-oxide In dichloromethane at 20℃; for 0.0166667h;95%
With tert.-butylhydroperoxide; potassium tert-butylate In water at 20 - 50℃; for 5h;90%
dibenzofuran
132-64-9

dibenzofuran

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
With sodium hydride at 190 - 192℃; for 7h;92.5%
With LiCrH4*2LiCl*2THF In tetrahydrofuran at 25℃; for 12h;84%
With lithium aluminium tetrahydride; cobalt acetylacetonate; sodium t-butanolate In toluene at 140℃; for 24h; Inert atmosphere; Sealed tube;81%
2-Bromobiphenyl
2052-07-5

2-Bromobiphenyl

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
With oxygen; triethylamine; sodium iodide In acetonitrile at 32℃; for 24h; Schlenk technique; UV-irradiation;91%
2-chloro-1,1'-biphenyl
2051-60-7

2-chloro-1,1'-biphenyl

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
With 5-(di-tert-butylphosphino)-1′, 3′, 5′-triphenyl-1′H-[1,4′]bipyrazole; tris-(dibenzylideneacetone)dipalladium(0); cesiumhydroxide monohydrate In 1,4-dioxane at 110℃; Inert atmosphere; Glovebox; Sealed tube;90%
With water; silica gel; copper(II) oxide at 525 - 600℃;
With water; sodium carbonate at 300 - 360℃;
(Z)-4-phenylocta-1,4,7-trien-3-one
863418-13-7

(Z)-4-phenylocta-1,4,7-trien-3-one

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride In dichloromethane at 20℃; for 2h;90%
(1,1'-biphenyl)-2-yl formate

(1,1'-biphenyl)-2-yl formate

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
With copper; Selectfluor In acetonitrile at 80℃;90%
potassium (2-hydroxyphenyl)trifluoroborate

potassium (2-hydroxyphenyl)trifluoroborate

iodobenzene
591-50-4

iodobenzene

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In ethanol; water; toluene at 80℃; Suzuki Coupling; Inert atmosphere; Sonication; Reflux;89%
Diethylcarbamic acid, <1,1'-biphenyl>-2-yl ester
132939-03-8

Diethylcarbamic acid, <1,1'-biphenyl>-2-yl ester

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
With zirconocene dichloride In tetrahydrofuran at 20℃; Inert atmosphere;87%
With water; sodium hydroxide In ethanol for 8h; Reflux;85%
dibenzothiophene sulfone
1016-05-3

dibenzothiophene sulfone

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
Stage #1: dibenzothiophene sulfone With sodium hydroxide In water at 300℃; for 1.5h; Autoclave;
Stage #2: With hydrogenchloride In water pH=7; Product distribution / selectivity;
86.5%
2-hydroxybromobenzene
95-56-7

2-hydroxybromobenzene

phenylmagnesium bromide
100-58-3

phenylmagnesium bromide

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
Stage #1: 2-hydroxybromobenzene; phenylmagnesium bromide With tris-(dibenzylideneacetone)dipalladium(0); 4-bromo-phenol; C30H23O2P In tetrahydrofuran at -78 - 25℃; for 2.16667h;
Stage #2: With hydrogenchloride In tetrahydrofuran; water
86%
With tris-(dibenzylideneacetone)dipalladium(0); 1-bromo-4-methoxy-benzene; C30H23O2P In tetrahydrofuran at -78 - 25℃; Inert atmosphere;96 %Spectr.
([1,1′-biphenyl]-2-yloxy)(tert-butyl)dimethylsilane
188646-07-3

([1,1′-biphenyl]-2-yloxy)(tert-butyl)dimethylsilane

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
With acetyl chloride In methanol86%
2-iodocyclohex-2-en-1-one
33948-36-6

2-iodocyclohex-2-en-1-one

phenylboronic acid
98-80-6

phenylboronic acid

A

2-phenylcyclohex-2-enone
4556-09-6

2-phenylcyclohex-2-enone

B

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
With palladium 10% on activated carbon; sodium carbonate In 1,4-dioxane; water at 20℃; for 24h; Suzuki-Miyaura Coupling;A 86%
B 4%
N-(phenoxy)-4-methylbenzenesulfonamide
65109-75-3

N-(phenoxy)-4-methylbenzenesulfonamide

benzene
71-43-2

benzene

A

4-Phenylphenol
92-69-3

4-Phenylphenol

B

2-hydroxyphenyl p-toluenesulfonimidate
65109-81-1

2-hydroxyphenyl p-toluenesulfonimidate

C

toluene-4-sulfonamide
70-55-3

toluene-4-sulfonamide

D

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
With trifluorormethanesulfonic acid; trifluoroacetic acid for 1h; Ambient temperature; Further byproducts given;A 14%
B 13%
C 85%
D 29%
N-(phenoxy)-4-methylbenzenesulfonamide
65109-75-3

N-(phenoxy)-4-methylbenzenesulfonamide

benzene
71-43-2

benzene

A

4-Phenylphenol
92-69-3

4-Phenylphenol

B

2-hydroxyphenyl p-toluenesulfonimidate
65109-81-1

2-hydroxyphenyl p-toluenesulfonimidate

C

toluene-4-sulfonamide
70-55-3

toluene-4-sulfonamide

D

4-hydroxyphenyl trifluoromethanesulfonate
65109-80-0

4-hydroxyphenyl trifluoromethanesulfonate

E

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
With trifluorormethanesulfonic acid; trifluoroacetic acid for 1h; Mechanism; Product distribution; Ambient temperature; other N-acyl- and N-sulfonyl-O-arylhydroxylamines under various reaction conditions, different nucleophiles;A 14%
B 13%
C 85%
D 3%
E 29%
toluene-4-sulfonic acid,2-hydroxyphenyl ester
35616-01-4

toluene-4-sulfonic acid,2-hydroxyphenyl ester

phenylmagnesium bromide
100-58-3

phenylmagnesium bromide

2-Phenylphenol
90-43-7

2-Phenylphenol

Conditions
ConditionsYield
Stage #1: phenylmagnesium bromide With C24H52Cl2O12P4Pd2 In tetrahydrofuran; 1,4-dioxane at 20℃; for 0.0833333h; Kumada-Corriu cross-coupling reaction; Inert atmosphere;
Stage #2: toluene-4-sulfonic acid,2-hydroxyphenyl ester In tetrahydrofuran; 1,4-dioxane at 110℃; for 24h; Kumada-Corriu cross-coupling reaction; Inert atmosphere; chemoselective reaction;
84%
acetyl chloride
75-36-5

acetyl chloride

2-Phenylphenol
90-43-7

2-Phenylphenol

2-acetoxybiphenyl
3271-80-5

2-acetoxybiphenyl

Conditions
ConditionsYield
With pyridine In dichloromethane for 3h;100%
With dmap; triethylamine In dichloromethane at 0 - 20℃; for 6h; Schlenk technique; Inert atmosphere;98%
allyl bromide
106-95-6

allyl bromide

2-Phenylphenol
90-43-7

2-Phenylphenol

2-(allyloxy)-1,1'-biphenyl
20281-39-4

2-(allyloxy)-1,1'-biphenyl

Conditions
ConditionsYield
With potassium carbonate In acetone at 60℃; for 20h;100%
With cesium fluoride In acetonitrile at 82℃;62%
With cesium fluoride In acetonitrile at 82℃;62%
formaldehyd
50-00-0

formaldehyd

2-Phenylphenol
90-43-7

2-Phenylphenol

2-hydroxy-3-phenylbenzaldehyde
14562-10-8

2-hydroxy-3-phenylbenzaldehyde

Conditions
ConditionsYield
With triethylamine; magnesium chloride In tetrahydrofuran for 3h; Heating;100%
Stage #1: formaldehyd; 2-Phenylphenol With triethylamine; magnesium chloride In tetrahydrofuran for 1.7h; Heating / reflux;
Stage #2: With hydrogenchloride In water at 0℃; pH=5;
92%
With triethylamine; magnesium chloride In tetrahydrofuran at 70℃; for 16h;90%
propargyl bromide
106-96-7

propargyl bromide

2-Phenylphenol
90-43-7

2-Phenylphenol

1-phenyl-2-(2-propynyloxy)benzene
26627-30-5

1-phenyl-2-(2-propynyloxy)benzene

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 2h;100%
With potassium carbonate In acetone; toluene at 65℃; for 14h;95%
With potassium carbonate In acetone; toluene95%
trifluoromethylsulfonic anhydride
358-23-6

trifluoromethylsulfonic anhydride

2-Phenylphenol
90-43-7

2-Phenylphenol

biphenyl-2-yl trifluoromethanesulfonate
17763-65-4

biphenyl-2-yl trifluoromethanesulfonate

Conditions
ConditionsYield
With pyridine In dichloromethane at 0℃; for 2h;100%
With 2,6-dimethylpyridine In dichloromethane at 0 - 20℃; for 2h; Inert atmosphere;98%
With pyridine In dichloromethane at 20℃; for 2h; Inert atmosphere;95%
2-Phenylphenol
90-43-7

2-Phenylphenol

p-chlorodibenzo[c.e][1,2]oxaphosphorine
22749-43-5

p-chlorodibenzo[c.e][1,2]oxaphosphorine

Conditions
ConditionsYield
With zinc(II) chloride; phosphorus trichloride at 20 - 180℃; for 7h;100%
With anhydrous phosphorus trichloride; phosphorus trichloride; Zinc chloride In 5,5-dimethyl-1,3-cyclohexadiene95%
Stage #1: 2-Phenylphenol With phosphorus trichloride at 140℃; for 5h; Inert atmosphere; Neat (no solvent);
Stage #2: With zinc(II) chloride at 210℃; for 3h; Inert atmosphere; Neat (no solvent);
90%
titanium tetrachloride
7550-45-0

titanium tetrachloride

2-Phenylphenol
90-43-7

2-Phenylphenol

trichloro mono(2-phenylphenoxide) titanium(IV)
263547-03-1

trichloro mono(2-phenylphenoxide) titanium(IV)

Conditions
ConditionsYield
In dichloromethane byproducts: HCl; under N2; 2-phenylphenol in CH2Cl2 added to TiCl4 (molar ratio 1:1) in CH2Cl2; refluxed for 12.5 h; filtered; solvent removed; dried under vac. for 4 h; elem. anal.;100%
titanium tetrachloride
7550-45-0

titanium tetrachloride

2-Phenylphenol
90-43-7

2-Phenylphenol

[dichlorobis(2-phenylphenolate)titanium(IV)]
864720-65-0

[dichlorobis(2-phenylphenolate)titanium(IV)]

Conditions
ConditionsYield
In toluene byproducts: HCl; N2, vigorously refluxed for 12 h; cooled, filtered, solvent removed;100%
phenylethylketene
20452-67-9

phenylethylketene

2-Phenylphenol
90-43-7

2-Phenylphenol

2-phenylphenyl 2-phenylbutanoate

2-phenylphenyl 2-phenylbutanoate

Conditions
ConditionsYield
With potassium hexamethylsilazane In toluene100%
3-phenylpentan-3-ol
1565-71-5

3-phenylpentan-3-ol

2-Phenylphenol
90-43-7

2-Phenylphenol

C23H24O
1186337-44-9

C23H24O

Conditions
ConditionsYield
With sulfuric acid In water for 1h; Reflux;100%
2-Phenylphenol
90-43-7

2-Phenylphenol

ortho-nitrofluorobenzene
1493-27-2

ortho-nitrofluorobenzene

2-(2-nitrophenoxy)biphenyl
2688-91-7

2-(2-nitrophenoxy)biphenyl

Conditions
ConditionsYield
With potassium carbonate In dimethyl sulfoxide at 95℃; for 24h;100%
Stage #1: 2-Phenylphenol With sodium hydride In N,N-dimethyl-formamide at 20℃; for 1h; Inert atmosphere;
Stage #2: ortho-nitrofluorobenzene In N,N-dimethyl-formamide at 20 - 50℃; for 13h; Inert atmosphere;
83%
N,N-diisopropylcarbamoyl chloride
19009-39-3

N,N-diisopropylcarbamoyl chloride

2-Phenylphenol
90-43-7

2-Phenylphenol

[1,1'-biphenyl]-2-yl diisopropylcarbamate

[1,1'-biphenyl]-2-yl diisopropylcarbamate

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 20℃; for 12h; Sealed tube;100%
[1,3]-dioxolan-2-one
96-49-1

[1,3]-dioxolan-2-one

2-Phenylphenol
90-43-7

2-Phenylphenol

2-(<1,1'-biphenyl>2-yloxy)ethanol
7501-02-2

2-(<1,1'-biphenyl>2-yloxy)ethanol

Conditions
ConditionsYield
With potassium carbonate at 160℃; for 1h; Temperature; Reagent/catalyst;99.2%
N,N-diethylcarbamyl chloride
88-10-8

N,N-diethylcarbamyl chloride

2-Phenylphenol
90-43-7

2-Phenylphenol

Diethylcarbamic acid, <1,1'-biphenyl>-2-yl ester
132939-03-8

Diethylcarbamic acid, <1,1'-biphenyl>-2-yl ester

Conditions
ConditionsYield
With potassium carbonate In acetonitrile for 3h; Inert atmosphere; Reflux;99%
With potassium carbonate In acetonitrile for 7h; Heating;95%
With potassium carbonate In acetonitrile for 8h; Reflux;
2-Phenylphenol
90-43-7

2-Phenylphenol

acetone
67-64-1

acetone

2,2-bis-(3-phenyl-4-hydroxyphenyl)-propane
24038-68-4

2,2-bis-(3-phenyl-4-hydroxyphenyl)-propane

Conditions
ConditionsYield
With hydrogenchloride; 3-mercaptopropionic acid In water at 80℃; Reagent/catalyst; Inert atmosphere;99%
With hydrogenchloride for 18h; Heating;42%
With methanol; sulfuric acid; 1-dodecylthiol In toluene at 40℃; for 2.5h; Inert atmosphere;9 %Chromat.
2-Phenylphenol
90-43-7

2-Phenylphenol

Isopropyl isocyanate
1795-48-8

Isopropyl isocyanate

O-2-biphenylyl N-isopropylcarbamate
417698-00-1

O-2-biphenylyl N-isopropylcarbamate

Conditions
ConditionsYield
With dmap In tetrahydrofuran at 60℃; for 24h;99%
2-Phenylphenol
90-43-7

2-Phenylphenol

dibenzo[c,e][1,2]oxaborinin-6-ol
14205-96-0

dibenzo[c,e][1,2]oxaborinin-6-ol

Conditions
ConditionsYield
With boron trichloride; aluminium trichloride In hexane at 70 - 75℃; for 6h;99%
Multi-step reaction with 2 steps
1: (i) BCl3, CH2Cl2, (ii) AlCl3, PE
2: Et2O / light petroleum
View Scheme
With boron trichloride
2-Phenylphenol
90-43-7

2-Phenylphenol

3-bromo[1,1’-biphenyl]-2-ol
23197-48-0

3-bromo[1,1’-biphenyl]-2-ol

Conditions
ConditionsYield
With N-bromo-tert-butylamine In chloroform at 0℃; Inert atmosphere;99%
With N-Bromosuccinimide; diisopropylamine In dichloromethane for 16h; Reflux; Inert atmosphere;96%
With N-Bromosuccinimide; diisopropylamine In dichloromethane for 16h; Inert atmosphere; Reflux;95%
(2R,4R)-pentanediol
42075-32-1

(2R,4R)-pentanediol

2-Phenylphenol
90-43-7

2-Phenylphenol

C17H20O2
1373521-55-1

C17H20O2

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 20℃; for 96h; Mitsunobu reaction;99%
diphenyliodonium tetrafluoroborate

diphenyliodonium tetrafluoroborate

2-Phenylphenol
90-43-7

2-Phenylphenol

1-methoxy-3-phenoxybenzene
1655-68-1

1-methoxy-3-phenoxybenzene

Conditions
ConditionsYield
Stage #1: 2-Phenylphenol With potassium tert-butylate In tetrahydrofuran at 0℃; for 0.25h;
Stage #2: diphenyliodonium tetrafluoroborate In tetrahydrofuran at 20℃; for 3h;
99%
bis(2-methylphenyl)iodonium tetrafluoroborate

bis(2-methylphenyl)iodonium tetrafluoroborate

2-Phenylphenol
90-43-7

2-Phenylphenol

1-(3-methoxyphenoxy)-2-methylbenzene
23951-29-3

1-(3-methoxyphenoxy)-2-methylbenzene

Conditions
ConditionsYield
Stage #1: 2-Phenylphenol With potassium tert-butylate In tetrahydrofuran at 0℃; for 0.25h;
Stage #2: bis(2-methylphenyl)iodonium tetrafluoroborate In tetrahydrofuran at 40℃; for 0.5h;
99%
2-Phenylphenol
90-43-7

2-Phenylphenol

N,N`-sulfuryldiimidazole
7189-69-7

N,N`-sulfuryldiimidazole

(1,1'-biphenyl)-2-yl 1H-imidazole-1-sulfonate

(1,1'-biphenyl)-2-yl 1H-imidazole-1-sulfonate

Conditions
ConditionsYield
With caesium carbonate In tetrahydrofuran99%
With caesium carbonate In tetrahydrofuran at 20℃; for 12h;98%
4-tert-Butylcatechol
98-29-3

4-tert-Butylcatechol

4-(4-chlorophenoxy)-3,5,6-trifluorophthalonitrile

4-(4-chlorophenoxy)-3,5,6-trifluorophthalonitrile

2-Phenylphenol
90-43-7

2-Phenylphenol

C36H25ClN2O4

C36H25ClN2O4

Conditions
ConditionsYield
Stage #1: 4-tert-Butylcatechol; 4-(4-chlorophenoxy)-3,5,6-trifluorophthalonitrile With potassium carbonate In acetonitrile at 80℃; for 2h;
Stage #2: 2-Phenylphenol With potassium carbonate In acetonitrile at 80℃; for 10h;
99%
1-iodo-butane
542-69-8

1-iodo-butane

carbon monoxide
201230-82-2

carbon monoxide

2-Phenylphenol
90-43-7

2-Phenylphenol

valeric acid biphenyl-2-yl ester
854880-18-5

valeric acid biphenyl-2-yl ester

Conditions
ConditionsYield
With rhodium(III) chloride; 1,3-bis-(diphenylphosphino)propane; sodium carbonate; sodium bromide In 1,4-dioxane at 120℃; under 750.075 Torr; for 24h; Inert atmosphere; chemoselective reaction;99%
sodium benzenesulfonate
873-55-2

sodium benzenesulfonate

2-Phenylphenol
90-43-7

2-Phenylphenol

[1,1’-biphenyl]-2-yl benzenesulfonate
21419-72-7

[1,1’-biphenyl]-2-yl benzenesulfonate

Conditions
ConditionsYield
In water; acetonitrile at 20℃; for 2h; Electrochemical reaction;99%

2-Phenylphenol Chemical Properties

Molecule structure of 2-Phenylphenol (CAS NO.90-43-7):

IUPAC Name: 2-Phenylphenol 
Molecular Weight: 170.2072 g/mol
Molecular Formula: C12H10
Density: 1.111 g/cm3 
Melting Point: 57-59 °C(lit.)
Boiling Point: 282 °C at 760 mmHg 
Flash Point: 140.3 °C
Index of Refraction: 1.604
Molar Refractivity: 52.72 cm3
Molar Volume: 153.1 cm3 
Surface Tension: 44.5 dyne/cm
Enthalpy of Vaporization: 54.18 kJ/mol
Vapour Pressure: 0.00202 mmHg at 25 °C 
Storage Temp.: 0-6 °C
Water Solubility: 0.7 g/L (20 °C)
Sensitive: hygroscopic
XLogP3: 3.1
H-Bond Donor: 1
H-Bond Acceptor: 1
Rotatable Bond Count: 1
Tautomer Count: 3
Exact Mass: 170.073165
MonoIsotopic Mass: 170.073165
Topological Polar Surface Area: 20.2
Heavy Atom Count: 13
Canonical SMILES: C1=CC=C(C=C1)C2=CC=CC=C2O
InChI: InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H
InChIKey: LLEMOWNGBBNAJR-UHFFFAOYSA-N
EINECS: 201-993-5
Product Categories: Industrial/Fine Chemicals; Aromatic Compounds; Biphenyl & Diphenyl ether

2-Phenylphenol Uses

 2-Phenylphenol (CAS NO.90-43-7) is commonly used as a carrier for hydrophobic synthetic polyvinyl chloride fiber, polyester when using carrier dyeing methos.It also can be used as surface-active agent, sterilizing preservatives, dyes intermediates. The primary use of 2-phenylphenol is as an agricultural fungicide. It is also used for disinfection of seed boxes. It is used to disinfect hospital and veterinary equipment. It is a general surface disinfectant, used in households, hospitals, nursing homes, farms, laundries, barber shops, and food processing plants. It can be used on fibers and other materials. Other uses are in rubber industry and as a laboratory reagent. It is also used in the manufacture of other fungicides, dye stuffs, resins and rubber chemicals.

2-Phenylphenol Toxicity Data With Reference

1.    

skn-rbt 250 mg

    MccSB#    Personal Communication from Susan B. McCollister, Dow Chemical U.S.A., Midland, MI 48640, to NIOSH, Cincinnati, OH 45226, June 15, 1984 15JUN84
2.    

skn-rbt 20 mg/24H MOD

    85JCAE    Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,228.
3.    

eye-rbt 50 µg/24H SEV

    85JCAE    Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,228.
4.    

mmo-sat 60 µg/plate

    ENMUDM    Environmental Mutagenesis. 5 (Suppl 1)(1983),3.
5.    

cyt-hmn:fbr 200 µg/L

    MUREAV    Mutation Research. 54 (1978),255.
6.    

msc-hmn:emb 20 mg/L

    MUREAV    Mutation Research. 156 (1985),123.
7.    

msc-hmn:oth 15 mg/L

    TRENAF    Kenkyu Nenpo-Tokyo-toritsu Eisei Kenkyusho. 35 (1984),399.
8.    

cyt-ham:ovr 100 mg/L

    MUREAV    Mutation Research. 141 (1984),95.
9.    

orl-rat LD50:2000 mg/kg

    NNGADV    Nippon Noyaku Gakkaishi. 3 (1978),365.
10.    

unr-rat LD50:2700 mg/kg

    TRENAF    Kenkyu Ne

2-Phenylphenol Consensus Reports

IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon. France.: ) (single copies can be ordered from WHO Publications centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man 30 (1983),p. 329.(World Health Organization, Internation Agency for Research on Cancer,Lyon. France.: ) (single copies can be ordered from WHO Publications centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; NTP Carcinogenesis Studies (dermal); No Evidence: mouse NTPTR*    National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-301,86 . . Reported in EPA TSCA Inventory. On Community Right-To-Know List.

2-Phenylphenol Safety Profile

Hazard Codes: IrritantXi, DangerousN
Risk Statements: 36/37/38-50-37/38/50-36 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R50:Very toxic to aquatic organisms. 
R37/38:Irritating to respiratory system and skin. 
R36:Irritating to eyes.
Safety Statements: 22-61 
S22:Do not breathe dust. 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 3077 9/PG 3
WGK Germany: 2
RTECS: DV5775000
HazardClass: 9
PackingGroup: III
HS Code: 29071900
A poison by intraperitoneal route. Moderately toxic by ingestion and possibly other routes. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. Severe eye and moderate skin irritant. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits acrid smoke and irritating fumes.

2-Phenylphenol Specification

 2-Phenylphenol (CAS NO.90-43-7) is also named as 'Dowicide A' ; (1,1'-Biphenyl)-2-ol ; 1-Hydroxy-2-phenylbenzene ; 2-Biphenylol ; 2-Fenylfenol ; 2-Fenylfenol [Czech] ; 2-Hydroxybifenyl ; 2-Hydroxybifenyl [Czech] ; 2-Hydroxybiphenyl ; 2-Hydroxydiphenyl ; 4-06-00-04579 (Beilstein Handbook Reference) ; AI3-00062 ; Anthrapole 73 ; BRN 0606907 ; Biphenyl, 2-hydroxy- ; Biphenyl-2-o1 ; CCRIS 1388 ; Caswell No. 623AA ; Dowicide 1 ; Dowicide 1 antimicrobial ;
EPA Pesticide Chemical Code 064103 ; HSDB 1753 ; Invalon OP ; Kiwi lustr 277 ; NCI-C50351 ; NSC 1548 ; Nectryl
OPP [pesticide] ; Orthohydroxydiphenyl ; Orthophenylphenol ; Orthoxenol ; Phenol, o-phenyl- ; Phenyl-2 phenol ; USAF EK-2219 ; o-Biphenylol ; o-Diphenylol ; o-Hydroxybiphenyl ; o-Hydroxydiphenyl ; o-Phenyl phenol ; o-Phenylphenol ; o-Phenylphenol, cosmetic grade ; o-Xenol . 2-Phenylphenol (CAS NO.90-43-7) is off-white powder. It is insoluble in water.
2-Phenylphenol react as a weak organic acid. Exothermically neutralizes bases. It may react with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides to generate flammable gas (H2) and the heat of the reaction may ignite the gas. Is sulfonated very readily (for example, by concentrated sulfuric acid at room temperature) in exothermic reactions. May be nitrated very rapidly. It can react with oxidizing agents. 2-Phenylphenol is combustible.

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