4-(Trifluoromethyl)pyridine supplier

Name
4-(Trifluoromethyl)pyridine
EINECS -0
CAS No. 3796-24-5
Article Data31
CAS DataBase
Density 1.266 g/cm³
Solubility
Melting Point
Formula C₆H₄F₃N
Boiling Point 141.7 °C at 760 mmHg
Molecular Weight 147.1
Flash Point 39.5 °C
Transport Information UN 1993 3/PG 2
Appearance colorless liquid
Safety 16-26-36-37/60
Risk Codes 11-36/37/38
Molecular Structure
Hazard Symbols F,Xi
Synonyms Pyridine, 4-trifluoromethyl-;
PSA 12.89000
LogP 2.10040

Synthetic route

: 22253-59-4
1-oxido-4-(trifluoromethyl)pyridin-1-ium

: 3796-24-5
4-trifluoromethylpyridine

Conditions

Conditions	Yield
With phenylsilane; 3-Methyl-1-phenyl-2-phospholene 1-oxide In acetonitrile for 16h; Irradiation; chemoselective reaction;	93%

: 15854-87-2
4-iodopyridine

: trifluoromethanesulfonic acid diphenyl(trifluoromethyl)sulfonium salt

: 3796-24-5
4-trifluoromethylpyridine

Conditions

Conditions	Yield
With copper In N,N-dimethyl-formamide at 60℃; for 11h;	91%

: 55-22-1
pyridine-4-carboxylic acid

: 3796-24-5
4-trifluoromethylpyridine

Conditions

Conditions	Yield
With F6Mo at 170 - 190℃; for 40h;	80%

: 339539-96-7
3-hydroxy-3-trifluoromethyl-1,5-pentanedialdehyde

: 3796-24-5
4-trifluoromethylpyridine

Conditions

Conditions	Yield
With ammonia In methanol for 24h; Heating;	70%
With ammonium hydroxide In methanol for 24h; Reflux;	70%

: 81565-18-6
2-chloro-4-trifluoromethyl pyridine

: 3796-24-5
4-trifluoromethylpyridine

Conditions

Conditions	Yield
With propylamine In tetrahydrofuran at 20℃; for 15h; Reagent/catalyst; Solvent; Inert atmosphere; Irradiation; Sealed tube;	68%
With triethylamine; Lumogen F Orange 240 In N,N-dimethyl-formamide at 40℃; for 16h; Irradiation;	91 %Chromat.
With ZnSe/CdS core/shell QDs; N-ethyl-N,N-diisopropylamine In hexane at 25℃; for 48h; Irradiation; Inert atmosphere;	23 %Chromat.

: 15854-87-2
4-iodopyridine

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 3796-24-5
4-trifluoromethylpyridine

Conditions

Conditions	Yield
With potassium fluoride; copper(l) iodide In 1-methyl-pyrrolidin-2-one; N,N-dimethyl-formamide at 25℃; for 6h;	25%
With C13H27CuN2O(1+) In N,N-dimethyl-formamide at 25℃; for 112h;	99 %Spectr.

: 110-86-1
pyridine

: 75-63-8
Bromotrifluoromethane

A: 3796-24-5
4-trifluoromethylpyridine

B: 3796-23-4
3-(trifluoromethyl)pyridine

C: 368-48-9
2-(trifluoromethyl)pyridine

Conditions

Conditions	Yield
With dipotassium hydrogenphosphate; sodium dithionite In water at 65℃; under 2250.2 - 3750.3 Torr; for 2h;	A 5% B 1% C 4%

...Expand

: 110-86-1
pyridine

: 2314-97-8
iodotrifluoromethane

A: 3796-24-5
4-trifluoromethylpyridine

B: 3796-23-4
3-(trifluoromethyl)pyridine

C: 20857-47-0
3,5-bis(trifluoromethyl)pyridine

D: 455-00-5
2,6-bis-(trifluoromethyl)pyridine

E: 368-48-9
2-(trifluoromethyl)pyridine

Conditions

Conditions	Yield
for 96h; Product distribution; Irradiation; The yields, the kind of products depend on the time of the irrad. and/or the temp., and the mol. ratio. Other trifluorometh. agents investigated;

...Expand

: 36610-32-9
4-hydroxy-4-trifluoromethyl-1,6-heptadiene

: 3796-24-5
4-trifluoromethylpyridine

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 90 percent / O3 / CH2Cl2; methanol / 24 h / -78 °C 2: 70 percent / NH3 / methanol / 24 h / Heating View Scheme
Multi-step reaction with 2 steps 1.1: ozone / dichloromethane; methanol / -78 °C 1.2: 2 h / 20 °C 2.1: ammonium hydroxide / methanol / 24 h / Reflux View Scheme

: 110-86-1
pyridine

: 887144-97-0
Togni's reagent

A: 3796-24-5
4-trifluoromethylpyridine

B: 3796-23-4
3-(trifluoromethyl)pyridine

C: 368-48-9
2-(trifluoromethyl)pyridine

Conditions

Conditions	Yield
In acetonitrile at 80℃; for 96h; Inert atmosphere;	A 3 %Spectr. B 16 %Spectr. C 17 %Spectr.

...Expand

: 2314-97-8
iodotrifluoromethane

: 1692-15-5
4-pyridylboronic acid

: 3796-24-5
4-trifluoromethylpyridine

Conditions

Conditions	Yield
With tris(bipyridine)ruthenium(II) dichloride hexahydrate; copper (I) acetate; potassium carbonate In N,N-dimethyl-formamide at 60℃; for 12h; Inert atmosphere; 26 W fluorescent light bulbs;	64 %Spectr.

: 77152-08-0
trifluoromethylcopper(I)

: 1692-15-5
4-pyridylboronic acid

: 3796-24-5
4-trifluoromethylpyridine

Conditions

Conditions	Yield
With oxygen; triethylamine tris(hydrogen fluoride) In N,N-dimethyl-formamide at 25℃; for 4h;	67 %Spectr.

: 77152-08-0
trifluoromethylcopper(I)

: 19524-06-2
4-bromopyridine hydrochloride

: 3796-24-5
4-trifluoromethylpyridine

Conditions

Conditions	Yield
With triethylamine tris(hydrogen fluoride) In N,N-dimethyl-formamide at 23 - 50℃; for 39h; Glovebox; Sealed tube;	74 %Spectr.

: 1120-87-2
4-bromopyridin

: (1,10-phenanthroline)(trifluoromethyl)copper (I)

: 3796-24-5
4-trifluoromethylpyridine

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 100℃; for 8h; Sealed tube; Inert atmosphere;	75 %Spectr.

: 15854-87-2
4-iodopyridine

: trimethylsilyl 2-chloro-2,2-difluoroacetate

: 3796-24-5
4-trifluoromethylpyridine

Conditions

Conditions	Yield
With copper(l) iodide; N,N,N,N,-tetramethylethylenediamine; silver fluoride In N,N-dimethyl-formamide at 100℃; for 2h; Time; Inert atmosphere; Sealed tube;	83 %Spectr.

: 1122-58-3
dmap

: bis(4-(trifluoromethyl)pyridine)iodonium tetrafluoroborate

A: 3796-24-5
4-trifluoromethylpyridine

B: bis(4-(dimethylamino)pyridine)iodonium tetrafluoroborate

Conditions

Conditions	Yield
In dichloromethane Kinetics;

...Expand

: 110-86-1
pyridine

: [(Py)2NiF2(CF3)2]

A: 3796-24-5
4-trifluoromethylpyridine

B: 3796-23-4
3-(trifluoromethyl)pyridine

C: 368-48-9
2-(trifluoromethyl)pyridine

: [(Py)2Ni(CF3)2]

Conditions

Conditions	Yield
In neat (no solvent) at 25℃; Schlenk technique; Inert atmosphere; Glovebox;

...Expand

: 175205-81-9
2-bromo-4-(trifluoromethyl)pyridine

: 3796-24-5
4-trifluoromethylpyridine

Conditions

Conditions	Yield
With ZnSe/CdS core/shell QDs; N-ethyl-N,N-diisopropylamine In hexane at 25℃; for 48h; Irradiation; Inert atmosphere;	39 %Chromat.

: 1120-87-2
4-bromopyridin

: dimesityl(trifluoromethyl)sulfonium trifluoromethanesulfonate

: 3796-24-5
4-trifluoromethylpyridine

Conditions

Conditions	Yield
With dilithium tetrabromocuprate; 1,1,1,3,3,3-hexamethyl-2-(trimethylsilyl)-2-trisilanol; Ir(2-(2,4-difluorophenyl)-5-fluoropyridine)2(4,4'-di(trifluoromethyl)-2,2'-bipyridyl)PF6; sodium carbonate In acetone at 35℃; Irradiation;

: 110-86-1
pyridine

: 76-05-1
trifluoroacetic acid

A: 3796-24-5
4-trifluoromethylpyridine

B: 3796-23-4
3-(trifluoromethyl)pyridine

C: 368-48-9
2-(trifluoromethyl)pyridine

Conditions

Conditions	Yield
In acetonitrile at 20℃; Catalytic behavior; Reagent/catalyst; Inert atmosphere; Electrolysis; Overall yield = 82 %Chromat.; regioselective reaction;

...Expand

: (2'-(dicyclohexylphosphino)-2,4,6-triisopropylbiphenyl)Ag(I)(μ-OH)CuIII(CF3)3

: 1692-15-5
4-pyridylboronic acid

: 3796-24-5
4-trifluoromethylpyridine

Conditions

Conditions	Yield
With potassium fluoride In N,N-dimethyl-formamide at 100℃; for 6h; Inert atmosphere; Schlenk technique;	36 %Spectr.

: C37H47BF3FeN5

A: 3796-24-5
4-trifluoromethylpyridine

B: Ph2B(tBuIm)2FeCH2tBu

Conditions

Conditions	Yield
In toluene for 2h; Equilibrium constant; Concentration; Inert atmosphere;

: C27H25BF3NO3

A: 3796-24-5
4-trifluoromethylpyridine

B: 28445-29-6
tris(4-methoxyphenyl)borane

Conditions

Conditions	Yield
In dichloromethane at 20℃;

: C27H25BF3N

A: 3796-24-5
4-trifluoromethylpyridine

B: 7297-94-1
tri-p-tolylborane

Conditions

Conditions	Yield
In dichloromethane at 20℃;

: C24H19BF3N

A: 3796-24-5
4-trifluoromethylpyridine

B: 960-71-4
triphenylborane

Conditions

Conditions	Yield
In dichloromethane at 20℃;

: C24H16BF6N

A: 3796-24-5
4-trifluoromethylpyridine

B: 47196-74-7
tris(4-fluorophenyl)borane

Conditions

Conditions	Yield
In dichloromethane at 20℃;

: 3796-24-5
4-trifluoromethylpyridine

: 36016-40-7
mesitylenesulfonylhydroxylamine

: 1299420-32-8
1-amino-4-trifluoromethylpyridinium 2,4,6-trimethylbenzenesulfonate

Conditions

Conditions	Yield
In dichloromethane at 0 - 20℃; for 18h;	100%
In dichloromethane at 0 - 20℃; for 21h;

: 3796-24-5
4-trifluoromethylpyridine

: 1320213-69-1
[Al(η1-allyl)3(4-dimethylaminopyridine)]

: 1320213-72-6
[Al(η1-allyl)2(κ-N-2-allyl-4-trifluoromethyl-1,2-dyhydripyridine-1-yl)(4-dimethylaminopyridine)]

Conditions

Conditions	Yield
In tetrahydrofuran-d8 under Ar, Schlenk technique; soln. of 4-CF3-pyridine in THF-d8 added to soln. of Al complex in THF-d8, react. for 20 h; evapn. under vac., oil dried under vac. for 2 h; elem. anal.;	99%
In tetrahydrofuran under Ar, Schlenk technique; Al complex and 4-CF3-pyridine in THF at room temp.;

: 3796-24-5
4-trifluoromethylpyridine

: 1320213-61-3
[Al(η1-allyl)3(triphenylphosphine oxide)]

: 1320213-73-7
[Al(η1-allyl)2(κ-N-2-allyl-4-trifluoromethyl-1,2-dyhydripyridine-1-yl)(triphenylphosphine oxide)]

Conditions

Conditions	Yield
In tetrahydrofuran under Ar, Schlenk technique; addn. of 4-CF3-pyridine to soln. of Al complex in THF, react. for 18 h; evapn. under vac., oil dried under vac. for 2 h; elem. anal.;	99%

: 12112-67-3
bis(1,5-cyclooctadiene)diiridium(I) dichloride

: 3796-24-5
4-trifluoromethylpyridine

: sodium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate

: bis(η4-1,5-cyclooctadiene)(4-(trifluoromethyl)pyridine)iridium(I) tetrakis[3,5-bis(trifluoromethyl)phenyl]borate

Conditions

Conditions	Yield
In dichloromethane react. of Ir complex with NC5H4CF3 (6-10 equiv.) at 23°C for 1 h,then NaB(C6H3(CF3)2)4 (1.2-1.5 equiv.) added, kept for 12 h;	99%

...Expand

: 3796-24-5
4-trifluoromethylpyridine

: [(1,3-bis-(2,6-diisopropylphenyl)-1,3-dihydro-2H-imidazol-2-ylidene)PdCl(μ-Cl)]2

: C33H40Cl2F3N3Pd

Conditions

Conditions	Yield
In dichloromethane at 20℃; for 16h; Inert atmosphere;	99%

: 3796-24-5
4-trifluoromethylpyridine

: [(1,3-dimesitylimidazol-2-ylidene)3[Fe4S4](diethyl ether)][tetrakis[(3,5-trifluoromethyl)phenyl]borate]

: [(IMes)3Fe4S4(4-CF3-pyridine)][BArF4]

Conditions

Conditions	Yield
In diethyl ether; benzene Inert atmosphere; Glovebox; Schlenk technique;	99%

: 3796-24-5
4-trifluoromethylpyridine

: 657-36-3
4-Trifluormethyl-piperidin

Conditions

Conditions	Yield
With [Rh(cod)(CI)(CAACMe2)]; hydrogen In hexane at 40℃; for 24h; Molecular sieve; diastereoselective reaction;	98%
With hydrogen In tetrahydrofuran at 30℃; under 15001.5 Torr; for 4h; Catalytic behavior; Autoclave; Glovebox;	49 %Chromat.
With hydrogen In water; isopropyl alcohol at 120℃; under 37503.8 Torr; for 24h; Autoclave;	94 %Chromat.

: 3796-24-5
4-trifluoromethylpyridine

: di-μ-bromo(dibromo)bis[1,3-di(propan-2-yl)-1,3-dihydro-2H-benzimidazol-2-ylidene]dipalladium(II)

: trans-dibromido(1,3-diisopropylbenzimidazolin-2-ylidene)(4-trifluoromethylpyridine)palladium(II)

Conditions

Conditions	Yield
In dichloromethane at 20℃; for 2h;	98%

: 3796-24-5
4-trifluoromethylpyridine

: 25015-63-8
4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

: 1360145-63-6
1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)-1,2-dihydropyridine

Conditions

Conditions	Yield
With [La(η5-C5(CH3)5)H]2 at 25 - 35℃; for 0.4h;	96%
With chloro(1,5-cyclooctadiene)rhodium(I) dimer; tricyclohexylphosphine In toluene at 50℃; for 24h; Inert atmosphere;	92%
With P(C6H11)3; chloro(1,5-cyclooctadiene)rhodium(I) dimer In toluene ligand reacted with pinacolborane in toluene at 50°C for 24 h in presence of (Rh(C8H12)Cl)2 and P(C6H11)3; treated with activated charcoal, filtered under N2, concd. in vacuo;	92%

: 3796-24-5
4-trifluoromethylpyridine

: 82113-65-3
bis(trifluoromethanesulfonyl)amide

: 4-(trifluoromethyl)pyridin-1-ium bis((trifluoromethyl)sulfonyl)amide

Conditions

Conditions	Yield
In dichloromethane at 22 - 26℃; for 0.75h; Inert atmosphere;	95%

: 67969-82-8
tetrafluoroboric acid diethyl ether

: 3796-24-5
4-trifluoromethylpyridine

: BF4(1-)*C6H4F3N*H(1+)

Conditions

Conditions	Yield
In diethyl ether at 0 - 20℃;	95%

: 3796-24-5
4-trifluoromethylpyridine

: 22253-59-4
1-oxido-4-(trifluoromethyl)pyridin-1-ium

Conditions

Conditions	Yield
With 3-chloro-benzenecarboperoxoic acid In dichloromethane for 24h; Inert atmosphere;	94%
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 0 - 20℃; for 16h;	86%
With 3-chloro-benzenecarboperoxoic acid In chloroform at 0 - 20℃; for 16.8h;	85%

: 623-73-4
diazoacetic acid ethyl ester

: 930-88-1
N-methylmaleimide

: 3796-24-5
4-trifluoromethylpyridine

: (3aR*,4R*,9aR*,9bS*)-ethyl-8-(trifluoromethyl)-2-methyl-1,3-dioxo-2,3,3a,4,9a,9b-hexahydro-1H-pyrrolo[3,4-a]indolizine-4-carboxylate

Conditions

Conditions	Yield
With [Fe(tetraphenylporphyrin)Cl] In toluene at 20℃; for 3h; Inert atmosphere;	94%

...Expand

: 3796-24-5
4-trifluoromethylpyridine

: 74-88-4
methyl iodide

: 1-methyl-4-trifluoromethyl-pyridinium chloride

Conditions

Conditions	Yield
Stage #1: 4-trifluoromethylpyridine; methyl iodide In acetonitrile at 20℃; Stage #2: With AG(R)21K anion exchange resin chloride form 50-100 mesh Further stages.;	93%

: 3796-24-5
4-trifluoromethylpyridine

: 865-50-9
iodomethane-d3

: 1-trideuteriomethyl-4-trifluoromethylpyridinium hexafluorophosphate

Conditions

Conditions	Yield
Stage #1: 4-trifluoromethylpyridine; iodomethane-d3 at 80℃; Stage #2: With ammonium hexafluorophosphate In water	92%

: 3796-24-5
4-trifluoromethylpyridine

: 866929-69-3
1-benzyl-4-(trifluoromethyl)-1,2,3,6-tetrahydropyridine

Conditions

Conditions	Yield
With sodium tetrahydroborate In ethanol at 0 - 14℃; for 1.5h;	92%

: 3796-24-5
4-trifluoromethylpyridine

: 79-22-1
methyl chloroformate

: 536-74-3
phenylacetylene

: methyl 2-(phenylethynyl)-4-(trifluoromethyl)pyridine-1(2H)-carboxylate

Conditions

Conditions	Yield
With copper(l) iodide; N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; Inert atmosphere;	92%

...Expand

: 3796-24-5
4-trifluoromethylpyridine

: 4891-38-7
phenylpropynoic acid methyl ester

: methyl 2-phenyl-5-(trifluoromethyl)pyrazolo[1,5-a]pyridine-3-carboxylate

Conditions

Conditions	Yield
With perchloric acid; ethyl o-mesitylsulfonylacetohydroxamic acid; potassium carbonate In tetrahydrofuran; 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide at 20℃; for 20h;	92%

: 3796-24-5
4-trifluoromethylpyridine

: 100-39-0
benzyl bromide

: 1443117-98-3
1-benzyl-4-(trifluoromethyl)pyridin-1-ium bromide

Conditions

Conditions	Yield
In acetonitrile at 90℃; for 12h; Inert atmosphere;	91%
In acetonitrile at 85℃; for 0.25h; Reflux;

: 3796-24-5
4-trifluoromethylpyridine

: 74-88-4
methyl iodide

: 1-methyl-4-trifluoromethylpyridinium hexafluorophosphate

Conditions

Conditions	Yield
Stage #1: 4-trifluoromethylpyridine; methyl iodide at 80℃; Stage #2: With ammonium hexafluorophosphate In water	90%

: 3796-24-5
4-trifluoromethylpyridine

: 1258790-68-9
[C2H5NC4H4B(O3SCF3)]

: C4H4N(C2H5)BNC5H4CF3(1+)*CF3SO3(1-)=(C4H4N(C2H5)BNC5H4CF3)(CF3SO3)

Conditions

Conditions	Yield
In dichloromethane at 20℃; for 4h; Inert atmosphere;	90%
In dichloromethane glovebox; soln. of substituted pyridine added to stirred soln. of azaborine, mixt. stirred for 1 h at room temp.; soln. cooled to -20 °C, left at this temp. for 24 h, after crystals pptd. supernatant decanted, solid washed with n-pentane, solvent removed (reduced pressure);	90%

: 3796-24-5
4-trifluoromethylpyridine

: 70-11-1
α-bromoacetophenone

: 140-88-5
ethyl acrylate

: C19H14F3NO3

Conditions

Conditions	Yield
Stage #1: 4-trifluoromethylpyridine; α-bromoacetophenone In N,N-dimethyl-formamide at 100℃; Stage #2: ethyl acrylate With sodium acetate; copper(II) acetate monohydrate In N,N-dimethyl-formamide at 100℃; for 16h;	88.9%

...Expand

: 3796-24-5
4-trifluoromethylpyridine

: 766-77-8
Dimethylphenylsilane

: 1-dimethylphenylsilyl-4-(trifluoromethyl)-1,4-dihydropyridine

Conditions

Conditions	Yield
With C29H38PRuS(1+)*C32H12BF24(1-) In neat (no solvent) at 20℃; for 12h; Inert atmosphere; Glovebox;	88%

: 3796-24-5
4-trifluoromethylpyridine

: 27607-77-8
trimethylsilyl trifluoromethanesulfonate

: 2CF3O3S(1-)*C12H8F6N2S(4+)

Conditions

Conditions	Yield
With sulfur dichloride In dichloromethane at -78℃; Inert atmosphere;	87%

: 3796-24-5
4-trifluoromethylpyridine

: dichlorobis(dimethyl sulfoxide)platinum(II)

: silver nitrate

: [PtII(4-trifluoromethylpyridine)4](NO3)2

Conditions

Conditions	Yield
In methanol for 24h; Reflux;	87%

...Expand

: 3796-24-5
4-trifluoromethylpyridine

: 824-94-2
p-methoxybenzyl chloride

: 1-(4-methoxybenzyl)-4-(trifluoromethyl)pyridin-1-ium chloride

Conditions

Conditions	Yield
In acetonitrile at 80℃;	87%

: 12112-67-3
bis(1,5-cyclooctadiene)diiridium(I) dichloride

: 3796-24-5
4-trifluoromethylpyridine

: sodium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate

: 2622-14-2
tricyclohexylphosphine

: (η4-1,5-cyclooctadiene)(tricyclohexylphosphane)[4-(trifluoromethyl)pyridine]iridium(I) tetrakis[3,5-bis(trifluoromethyl)phenyl]borate

Conditions

Conditions	Yield
In dichloromethane NC5H4CF3 (1 equiv.) added to soln. of Ir complex (0.5 equiv.) at 23°C, kept for 30 min, Cy3P (1 equiv.) added, after 30 min NaB(C6H3(CF3)2)4 (1.02 equiv.) added, kept for 1 h; concd., chromd. (SiO2, CH2CL2);	86%

...Expand

: 3796-24-5
4-trifluoromethylpyridine

: 124-38-9
carbon dioxide

: 158063-66-2
4-(trifluoromethyl)nicotinic acid

Conditions

Conditions	Yield
With 2,2,6,6-tetramethylpiperidinyl-lithium In tetrahydrofuran at -75℃; for 2h;	84%

4-(Trifluoromethyl)pyridine Chemical Properties

Molecular Structure:

Molecular Formula: C₆H₄F₃N
Molecular Weight: 147.0979
IUPAC Name: 4-(Trifluoromethyl)pyridine
Synonyms of 4-(Trifluoromethyl)pyridine (CAS NO.3796-24-5): Pyridine, 4-trifluoromethyl-
CAS NO: 3796-24-5
Classification Code: Pyridine series ; Pyridine ; Pyridines ; C6 ; Heterocyclic Building Blocks
Index of Refraction: 1.418
Molar Refractivity: 29.32 cm³
Molar Volume: 116.1 cm³
Surface Tension: 24.5 dyne/cm
Density: 1.266 g/cm³
Flash Point: 39.5 °C
Enthalpy of Vaporization: 36.32 kJ/mol
Boiling Point: 141.7 °C at 760 mmHg
Vapour Pressure: 7.24 mmHg at 25°C

4-(Trifluoromethyl)pyridine Uses

4-(Trifluoromethyl)pyridine (CAS NO.3796-24-5) is commonly used as pharmaceutical intermediate.

4-(Trifluoromethyl)pyridine Safety Profile

Hazard Codes of 4-(Trifluoromethyl)pyridine (CAS NO.3796-24-5): F, Irritant Xi
Risk Statements: 11-36/37/38
R11: Highly flammable.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 16-26-36-37/60
S16: Keep away from sources of ignition.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
S37: Wear suitable gloves.
S60: This material and its container must be disposed of as hazardous waste.
RIDADR: UN 1993 3/PG 2
WGK Germany: 3
Hazard Note: Irritant/Flammable
HazardClass: 3
PackingGroup: II

Product Name

4-(Trifluoromethyl)pyridine

Synthetic route

4-(Trifluoromethyl)pyridine Chemical Properties

4-(Trifluoromethyl)pyridine Uses

4-(Trifluoromethyl)pyridine Safety Profile

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