4-Isopropylbenzaldehyde supplier

Name
4-Isopropylbenzaldehyde
EINECS 204-516-9
CAS No. 122-03-2
Article Data233
CAS DataBase
Density 0.98 g/cm³
Solubility insoluble in water
Melting Point 235-236oC(lit.)
Formula C₁₀H₁₂O
Boiling Point 236.1 °C at 760 mmHg
Molecular Weight 148.205
Flash Point 93.3 °C
Transport Information
Appearance clear colorless to yellow liquid
Safety 26-37/39
Risk Codes 22-36/37/38
Molecular Structure
Hazard Symbols Xn,Xi
Synonyms 4-(1-Methylethyl)-Benzaldehyd;4-(1-Methylethyl)Benzaldehyde;4-(1-Methylethyl)-Benzaldehyde;4-(2-Propyl)Benzaldehyde;4-Ipr-Benzaldehyde;Benzaldehyde, P-Isopropyl-;Cumal;Cumic Aldehyde;Cumaldehyde;
PSA 17.07000
LogP 2.62250

Synthetic route

: 536-60-7
cuminol

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen In dichloromethane; water under 760.051 Torr; for 2h; Green chemistry;	100%
With dmap; C25H30F17N5O4S(1-)*K(1+); oxygen; copper(II) sulfate In water at 25℃; for 2h; chemoselective reaction;	99%
With titanium(IV) oxide; oxygen at 29.84℃; under 760.051 Torr; for 6h; Sealed tube; Irradiation;	99%

: 1888-75-1
isopropyllithium

: 1122-91-4
4-bromo-benzaldehyde

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
Stage #1: 4-bromo-benzaldehyde With bis(tri-tert-butylphosphine)palladium(0); sodium chloride In water at 20℃; for 0.166667h; Negishi Coupling; Schlenk technique; Stage #2: isopropyllithium With zinc(II) chloride In 2-methyltetrahydrofuran; water at 10℃; for 0.00555556h; Schlenk technique; chemoselective reaction;	98%

: 3717-17-7, 3717-18-8, 13372-80-0
4-isopropylbenzaldehyde oxime

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With iron(III) chloride; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen In water; toluene at 60℃; under 760.051 Torr; for 4h;	95%
With tungsten(VI) chloride; zinc In acetonitrile at 20℃; for 0.333333h;	92%

: 2-(4-isopropylphenyl)-1,3-dithiane

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With 1,3,5-trichloro-2,4,6-triazine; dimethyl sulfoxide In dichloromethane at 20℃; for 1h;	94%

: 23229-31-4
2-(4-isopropylphenyl)-1,3-dithiolane

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With 1,3,5-trichloro-2,4,6-triazine; dimethyl sulfoxide In dichloromethane at 20℃; for 2.45h;	93%
With Oxone; potassium bromide In water; acetonitrile at 20℃; for 0.333333h;	92%
With iodosylbenzene In dichloromethane at 20℃; for 0.25h;	91%

: 2055-40-5
4-isopropylstyrene

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With dihydrogen peroxide In acetonitrile at 65℃; for 6h;	93%
With sodium periodate In water; ethyl acetate; acetonitrile at 0℃; for 3.5h;	63%
Stage #1: 4-isopropylstyrene With BO40W12(5-)2C12H12N6Co(2+)3H(1+)10H2O In acetonitrile for 0.0833333h; Stage #2: With dihydrogen peroxide In acetonitrile at 70℃; for 7h;

: 2051-18-5
4-isopropylbenzyl chloride

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With potassium hydroxide; cetyltrimethylammonim bromide; potassium nitrate In water for 4h; pH=10 - 11; Reflux;	92%
With 4Na(1+)6H(1+)NiMo6O24(10-)=Na4H6NiMo6O24; oxygen In water; acetonitrile at 20℃; under 760.051 Torr; for 12h; Irradiation;	92%
With potassium nitrite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen; potassium bromide In water for 5h; Reflux;	89%

: 73789-86-3
4-i-propylbenzyl bromide

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With potassium nitrite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen In water for 4h; Reflux;	92%
Multi-step reaction with 2 steps 1: eosin y; oxygen / dimethyl sulfoxide / 12 h / 25 °C / Irradiation 2: eosin y / dimethyl sulfoxide / 24 h / 80 °C / Irradiation View Scheme

: 1122-91-4
4-bromo-benzaldehyde

: 77047-87-1
isopropyl zinc bromide

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
Stage #1: 4-bromo-benzaldehyde With C40H55Cl5N3Pd In toluene at 0℃; for 0.0833333h; Negishi Coupling; Inert atmosphere; Cooling with ice; Stage #2: isopropyl zinc bromide In tetrahydrofuran; toluene at 23℃; for 0.5h; Inert atmosphere;	92%
With dichloro(1,3-bis(2,6-bis(3-pentyl)phenyl)imidazolin-2-ylidene)(3-chloropyridyl)palladium(II) In tetrahydrofuran; toluene at 0 - 20℃; for 3h; Negishi coupling reaction; Inert atmosphere;	78%

: tert-butyl-(4-isopropyl-benzyloxy)-dimethyl-silane

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With N-hydroxyphthalimide; oxygen; cobalt(II) benzoate In acetonitrile at 20℃; for 0.666667h;	90%

: 7154-10-1
1,1-diacetoxy-1-(4-i-propylphenyl)methane

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With saccharin sulfonic acid at 90℃; for 0.0333333h; Neat (no solvent);	90%
With water at 20℃; for 0.166667h; Green chemistry;	96 %Chromat.

: 23229-35-8
2-(4-isopropyl-phenyl)-[1,3]oxathiolane

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With Iron(III) nitrate nonahydrate at 90℃; for 0.05h;	90%

: 71700-48-6
4-iso-propylbenzyl trimethylsilyl ether

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With N-hydroxyphthalimide; oxygen; cobalt(II) benzoate In acetonitrile at 20℃; for 0.333333h;	89%
With silica chromate; silica gel In dichloromethane at 20℃; for 0.666667h;	82%

: 394738-99-9
2-(4-Isopropylbenzyloxy)-tetrahydropyran

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With 1,4-dichloro-1,4-diazoniabicyclo[2,2,2]octane bis-chloride In water at 50℃; for 0.25h; pH=7;	88%

: 1475-10-1
1-(4-isopropylphenyl)ethanol

A: 536-66-3
4-Isopropylbenzoic acid

B: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With sodium nitrate; water; oxygen In dimethyl sulfoxide at 130℃; for 24h;	A 88% B 8%

: 4395-73-7
4-isopropylbenzylamine

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With immobilised amine transaminase from the moderate halophilic bacterium Halomonas elongata; sodium pyruvate In aq. phosphate buffer; dimethyl sulfoxide at 37℃; under 760.051 Torr; for 5h; pH=8;	84%

: 73789-86-3
4-i-propylbenzyl bromide

A: 122-03-2
(4-isopropylbenzaldehyde)

B: 536-60-7
cuminol

Conditions

Conditions	Yield
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen In water for 4h; Reflux;	A 19% B 76%

: 2051-18-5
4-isopropylbenzyl chloride

A: 536-66-3
4-Isopropylbenzoic acid

B: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With potassium hydroxide; cetyltrimethylammonim bromide; potassium nitrate In water for 4h; pH=10 - 11; Reflux;	A 2 g B 71%

: 98-82-8
Isopropylbenzene

: 124-38-9
carbon dioxide

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
Stage #1: carbon dioxide With zinc(II) cyanide; ruthenium trichloride; rhodium (III) acetate; cobalt(II) acetate; zirconium(IV) acetate for 1h; Autoclave; Stage #2: Isopropylbenzene at 50℃; under 15001.5 Torr; for 5h;	70.2%

: 3717-17-7, 3717-18-8, 13372-80-0
4-isopropylbenzaldehyde oxime

A: 13816-33-6
p-Cyanocumen

B: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With pyridine; N-chloro-succinimide In acetonitrile at 20℃;	A 70% B n/a

: 4476-28-2
(4-isopropylphenyl)acetic acid

A: 477219-29-7
1-(fluoromethyl)-4-isopropylbenzene

B: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With xenon fluoride In dichloromethane at 20℃; for 14 - 18h; Inert atmosphere;	A 67% B 10%

: 80041-89-0
isopropylboronic acid

: 17763-69-8
4-(trifluormethanesulfonyloxy)benzaldehyde

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With potassium phosphate; C20H34O3P2; [Pd(cinnamyl)Cl]2 In toluene at 110℃; for 12h; Suzuki-Miyaura Coupling; Inert atmosphere;	67%

: 99-87-6
4-methylisopropylbenzene

A: 33241-77-9
(4-Isopropyl-phenyl)-nitromethan

B: 95543-77-4
4-isopropylbenzyl nitrate

C: 122-00-9
para-methylacetophenone

D: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With ammonium cerium(IV) nitrate In acetonitrile at 17℃; for 0.666667h; Irradiation;	A 3% B 62% C 6% D 6%
With ammonium cerium(IV) nitrate In acetonitrile at 17℃; for 0.666667h; Irradiation; Further byproducts given;	A 3% B 62% C 6% D 6%

...Expand

: 91132-18-2
2-hydroxy-2-(4-isopropylphenyl)acetonitrile

A: 536-66-3
4-Isopropylbenzoic acid

B: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
Stage #1: 2-hydroxy-2-(4-isopropylphenyl)acetonitrile With (η(6)-benzene)chloro[1,2-bis(diphenylphosphino)ethane]ruthenium(II) chloride In benzene at 120℃; for 24h; Inert atmosphere; Schlenk technique; Stage #2: With water In dichloromethane; ethyl acetate; benzene for 24h;	A 58% B 36%

: 27546-49-2
4-isopropyl-1-cyclopropylbenzene

A: 86604-05-9
(E)-3-(4-isopropylphenyl)acrylaldehyde

B: 119200-34-9
5-(4-isopropylphenyl)isoxazoline

C: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With dinitrogen tetraoxide; triethylamine In dichloromethane at -30℃; for 1h;	A 28% B 50% C 7%
With dinitrogen tetraoxide In pentane at -30℃; for 6h;	A 41% B 40% C 10%
With dinitrogen tetraoxide In pentane at -30℃; for 6h;	A 40% B 40% C 10%
With dinitrogen tetraoxide In dichloromethane at -30℃; for 1h;	A 39% B 40% C 8%

...Expand

: 99-87-6
4-methylisopropylbenzene

A: 1195-32-0
1-methyl-4-isopropenylbenzene

B: 69897-58-1
2-(4-isopropylbenzyl)-1,4-benzoquinone

C: 81036-81-9
4-(2-hydroxy-2-propyl)benzene-1-carbaldehyde

D: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With sodium persulfate; sulfuric acid; silver nitrate; p-benzoquinone In water at 60℃; for 0.5h;	A 5% B 45% C 10% D 20%

...Expand

: 99-87-6
4-methylisopropylbenzene

A: 69897-58-1
2-(4-isopropylbenzyl)-1,4-benzoquinone

B: 81036-81-9
4-(2-hydroxy-2-propyl)benzene-1-carbaldehyde

C: 122-03-2
(4-isopropylbenzaldehyde)

D: 536-60-7
cuminol

Conditions

Conditions	Yield
With sodium persulfate; sulfuric acid; silver nitrate; p-benzoquinone In water at 60℃; for 0.5h; Further byproducts given;	A 45% B 10% C 20% D 5%

...Expand

: 99-87-6
4-methylisopropylbenzene

: 106-51-4
p-benzoquinone

A: 69897-58-1
2-(4-isopropylbenzyl)-1,4-benzoquinone

B: 81036-81-9
4-(2-hydroxy-2-propyl)benzene-1-carbaldehyde

C: 122-03-2
(4-isopropylbenzaldehyde)

D: 536-60-7
cuminol

Conditions

Conditions	Yield
With sodium persulfate; sulfuric acid; silver nitrate In water at 60℃; for 0.5h; Further byproducts given;	A 45% B 10% C 20% D 5%

...Expand

: 98-82-8
Isopropylbenzene

: 332047-72-0
tris(diformylamino)methane

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
Stage #1: Isopropylbenzene; tris(diformylamino)methane With aluminium trichloride In 1,2-dichloro-ethane at -13 - -1℃; for 14h; Stage #2: With water	38%
With aluminium trichloride In 1,2-dichloro-ethane at -13 - -1℃; for 14h;	38%

: 122-03-2
(4-isopropylbenzaldehyde)

: 3717-17-7, 3717-18-8, 13372-80-0
4-isopropylbenzaldehyde oxime

Conditions

Conditions	Yield
With hydroxylamine hydrochloride; sodium acetate In ethanol; water Reflux;	100%
With hydroxylamine hydrochloride; sodium carbonate In methanol; water at 20℃; for 19.5h;	99%
With bismuth(lll) trifluoromethanesulfonate; acetylhydroxamic acid In methanol for 24h; Reflux;	97%

: 2579-20-6
cis, trans-1,3-dimethylaminocyclohexane

: 122-03-2
(4-isopropylbenzaldehyde)

: 1217526-87-8
C28H38N2

Conditions

Conditions	Yield
In methanol at 20℃; Molecular sieve;	100%
In methanol at 20℃; Molecular sieve;

: 107-10-8
propylamine

: 122-03-2
(4-isopropylbenzaldehyde)

: 100617-19-4
C13H19N

Conditions

Conditions	Yield
at 20℃; for 12h;	100%

: 109-80-8
1.3-propanedithiol

: 122-03-2
(4-isopropylbenzaldehyde)

: 2-(4-isopropylphenyl)-1,3-dithiane

Conditions

Conditions	Yield
With 1-methyl-3-octylimidazolium hydrogen sulfate ionic liquid [OMIm]HSO4 inside the mesochannels of SBA-15-Pr-SO3H In neat (no solvent) at 20℃; for 2h; chemoselective reaction;	100%
With oxygen In acetonitrile at 20℃; for 24h; Irradiation; Green chemistry; chemoselective reaction;	95%
With cobalt(II) chloride In acetonitrile at 20℃;	93%
With boron trifluoride diethyl etherate In dichloromethane Inert atmosphere;

: C17H25NO3

: 122-03-2
(4-isopropylbenzaldehyde)

: C27H36N2O2

Conditions

Conditions	Yield
With ammonium acetate In ethanol at 20℃; for 17h; Inert atmosphere;	100%

: C21H27NO3

: 122-03-2
(4-isopropylbenzaldehyde)

: C31H38N2O2

Conditions

Conditions	Yield
With ammonium acetate In ethanol at 60℃; Inert atmosphere; Sealed tube;	100%

: C21H28FNO3

: 122-03-2
(4-isopropylbenzaldehyde)

: C31H37FN2O2

Conditions

Conditions	Yield
With ammonium acetate In ethanol at 20℃; for 16h; Inert atmosphere; Sealed tube;	100%

: 107-15-3
ethylenediamine

: 122-03-2
(4-isopropylbenzaldehyde)

: N,N‐bis(4‐isopropylbenzylidene)ethane‐1,2‐diamine

Conditions

Conditions	Yield
In ethanol at 20℃; for 6h;	99%
In methanol for 6h;	92%
In ethanol at 40℃; for 10h;	80%
at 120℃;
In methanol Inert atmosphere;

: 122-03-2
(4-isopropylbenzaldehyde)

: 536-66-3
4-Isopropylbenzoic acid

Conditions

Conditions	Yield
With C4H11FeMo6NO24(3-)*3C16H36N(1+); water; oxygen; sodium carbonate at 50℃; under 760.051 Torr; for 8h; Green chemistry;	99%
With 4H3N4H(1+)CuMo6O18(OH)6(4-); water; oxygen; sodium carbonate at 50℃; under 760.051 Torr; for 12h;	99%
With tris[2-(4,6-difluorophenyl)pyridinato-C2,N]-iridium(III); oxygen In acetonitrile at 20℃; Irradiation; Sealed tube; Green chemistry; chemoselective reaction;	95%

: 67-64-1
acetone

: 122-03-2
(4-isopropylbenzaldehyde)

: 74389-78-9, 81467-89-2
(E)-4-(4-isopropylphenyl)but-3-en-2-one

Conditions

Conditions	Yield
With sodium hydroxide In water at 20℃; for 6h; Claisen-Schmidt Condensation;	99%
With sodium hydroxide In water at 25℃; for 18h;	41%
With sodium hydroxide In water Ambient temperature;	16%
With sodium hydroxide In water at 25℃; for 12h;
With sodium hydroxide at 20℃; for 24h; Claisen-Schmidt Condensation;

: 2033-24-1
cycl-isopropylidene malonate

: 122-03-2
(4-isopropylbenzaldehyde)

: 58420-21-6
3-(p-isopropylphenyl)propionic acid

Conditions

Conditions	Yield
Stage #1: cycl-isopropylidene malonate; (4-isopropylbenzaldehyde) With formic acid; triethylamine In N,N-dimethyl-formamide at 0 - 80℃; for 14h; Stage #2: With hydrogenchloride; water In N,N-dimethyl-formamide pH=1 - 2;	99%

: 141-97-9
ethyl acetoacetate

: 122-03-2
(4-isopropylbenzaldehyde)

: 109-77-3
malononitrile

: 326915-75-7, 340812-03-5
6-amino-2,4-dihydro-4-(4-isopropylphenyl)-3-methylpyrano[2,3-c]pyrazole-5-carbonitrile

Conditions

Conditions	Yield
With hydrazine hydrate; heptakis(6-amino-6-deoxy)-β-cyclodextrin at 20℃; for 0.0166667h; Neat (no solvent);	99%
With hydrazine hydrate; 2-amino-2-hydroxymethyl-1,3-propanediol In ethanol; water at 20℃; for 2.5h; Green chemistry;	84%

...Expand

: 122-03-2
(4-isopropylbenzaldehyde)

: 109-77-3
malononitrile

: 26088-83-5
β,β-dicyano-4-isopropylstyrene

Conditions

Conditions	Yield
With Zn(N4,N4'-di(pyridin-4-yl)biphenyl-4,4'-dicarboxamide)(5-aminoisophthalate) In neat (no solvent) for 4h; Knoevenagel Condensation;	99%
With 1-butyl-1,2,4-triazolium tetrafluoroborate In ethanol; water at 70℃; for 0.25h; Reagent/catalyst; Knoevenagel Condensation;	92%
With tin dioxide In neat (no solvent) at 20℃; Knoevenagel Condensation; Green chemistry;	90%

: 83-72-7
2-Hydroxy-1,4-naphthoquinone

: 504-02-9
1,3-cylohexanedione

: 122-03-2
(4-isopropylbenzaldehyde)

: C26H22O4

Conditions

Conditions	Yield
With silica-supported tungstic acid In neat (no solvent) at 60℃; for 0.0666667h; Sonication; Green chemistry;	99%

...Expand

: 122-03-2
(4-isopropylbenzaldehyde)

: 25015-63-8
4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

: 2-((4-isopropylbenzyl)oxy)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Conditions

Conditions	Yield
With C34H28N6Zn In neat (no solvent) at 20℃; for 1h; Glovebox; Schlenk technique;	99%
With C24H34N5PSeTi In neat (no solvent) at 30℃; for 2h; Glovebox; Schlenk technique; chemoselective reaction;	96%
With [{2-(AdN=CH)–C4H3NK(THF)}n] at 30℃; for 1h; Inert atmosphere; Glovebox; Schlenk technique;	92 %Spectr.

: 617-86-7
triethylsilane

: 122-03-2
(4-isopropylbenzaldehyde)

: 53172-95-5
triethyl((4-isopropylbenzyl)oxy)silane

Conditions

Conditions	Yield
With C42H43BN3P2(1+)*C18HBF15(1-) In chloroform at 40℃; for 1h; Reagent/catalyst; Temperature; Schlenk technique; Glovebox;	99%

: 540-63-6
ethane-1,2-dithiol

: 122-03-2
(4-isopropylbenzaldehyde)

: 23229-31-4
2-(4-isopropylphenyl)-1,3-dithiolane

Conditions

Conditions	Yield
at 20℃;	99%

: 603-76-9
1-methylindole

: 122-03-2
(4-isopropylbenzaldehyde)

: bis(1-methyl-indol-3-yl)-4-isopropylphenylmethane

Conditions

Conditions	Yield
With ruthenium trichloride In methanol at 20℃; for 0.05h;	98%

: 119-53-9
2-hydroxy-2-phenylacetophenone

: 122-03-2
(4-isopropylbenzaldehyde)

: 5496-37-7
2‐(4‐isopropylphenyl)‐4,5‐diphenyl‐1H‐imidazole

Conditions

Conditions	Yield
With 4,4'-diiodobiphenyl; ammonium acetate In ethanol for 0.5h; Heating;	98%
With oxaline; ammonium acetate at 110℃; for 1h;	80%

: 66117-84-8
3-amino-2-methyl-6,7-methylenedioxyquinazolin-4(3H)-one

: 122-03-2
(4-isopropylbenzaldehyde)

: 1192243-22-3
3-[(4-isopropylbenzylidene)amino]-2-methyl-6,7-methylenedioxy-quinazolin-4(3H)-one

Conditions

Conditions	Yield
With hydrogenchloride In ethanol; water at 20℃; for 1h; diastereoselective reaction;	98%

: 28144-70-9
anthranilic acid amide

: 122-03-2
(4-isopropylbenzaldehyde)

: 83800-96-8
2,3-dihydro-2-(4-isopropylphenyl)quinazolin-4(1H)-one

Conditions

Conditions	Yield
With phosphatidylcholine In water at 80℃; for 1h; Green chemistry;	98%
With 1,3,5-trichloro-2,4,6-triazine In acetonitrile at 20℃; for 0.166667h; chemoselective reaction;	90%
With silica supported ceric ammonium nitrate (CAN*SiO2) In acetonitrile at 20℃; for 0.166667h;	90%

: 127-17-3
2-oxo-propionic acid

: 122-03-2
(4-isopropylbenzaldehyde)

: C12H16O2

Conditions

Conditions	Yield
With cyclohexane-1,2-dione hydrolase In aq. buffer at 30℃; for 48h; pH=6.5; Enzymatic reaction;	98%

: 934-32-7
1H-benzimidazol-2-amine

: 122-03-2
(4-isopropylbenzaldehyde)

: 109-77-3
malononitrile

: 932995-93-2
2-amino-4-(4-isopropylphenyl)-1,4-dihydrobenzo[4,5]imidazolo[1,2-a]pyrimidine-3-carbonitrile

Conditions

Conditions	Yield
With poly(vinylpyrrolidonium) perchlorate ([PVPH]ClO4) at 100℃; for 0.0666667h;	98%
With toluene-4-sulfonic acid In neat (no solvent) at 80℃; for 0.55h; Green chemistry;	92%
With 1-methyl-3-(trimethoxysilylpropyl)imidazolium hydrogen sulfate supported on rice husk ash In neat (no solvent) at 100℃; for 0.0833333h; Green chemistry;	88%

...Expand

: 38941-47-8
cyclohexanecarbohydrazide

: 122-03-2
(4-isopropylbenzaldehyde)

: (E)-N'-(4-isopropylbenzylidene)cyclohexanecarbohydrazide

Conditions

Conditions	Yield
In ethanol at 20℃; for 2h;	98%

: 1809-20-7
diisopropyl hydrogenphosphonate

: 122-03-2
(4-isopropylbenzaldehyde)

: 109-77-3
malononitrile

: diisopropyl [2,2-dicyano-1-(4-isopropylphenyl)ethyl]phosphonate

Conditions

Conditions	Yield
With dibutylamine In neat (no solvent) at 20℃; Green chemistry;	98%

...Expand

: 31273-58-2
1-(7-hydroxy-2,2-dimethylchroman-6-yl)ethanone

: 122-03-2
(4-isopropylbenzaldehyde)

: (E)-1-(7-hydroxy-2,2-dimethylchroman-6-yl)-3-(4-isopropylphenyl)prop-2-en-1-one

Conditions

Conditions	Yield
With potassium hydroxide In ethanol at 90℃; Claisen-Schmidt Condensation; Microwave irradiation;	98%

: 536-60-7
cuminol

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen In dichloromethane; water under 760.051 Torr; for 2h; Green chemistry;	100%
With dmap; C25H30F17N5O4S(1-)*K(1+); oxygen; copper(II) sulfate In water at 25℃; for 2h; chemoselective reaction;	99%
With titanium(IV) oxide; oxygen at 29.84℃; under 760.051 Torr; for 6h; Sealed tube; Irradiation;	99%

: 1888-75-1
isopropyllithium

: 1122-91-4
4-bromo-benzaldehyde

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
Stage #1: 4-bromo-benzaldehyde With bis(tri-tert-butylphosphine)palladium(0); sodium chloride In water at 20℃; for 0.166667h; Negishi Coupling; Schlenk technique; Stage #2: isopropyllithium With zinc(II) chloride In 2-methyltetrahydrofuran; water at 10℃; for 0.00555556h; Schlenk technique; chemoselective reaction;	98%

: 3717-17-7, 3717-18-8, 13372-80-0
4-isopropylbenzaldehyde oxime

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With iron(III) chloride; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; oxygen In water; toluene at 60℃; under 760.051 Torr; for 4h;	95%
With tungsten(VI) chloride; zinc In acetonitrile at 20℃; for 0.333333h;	92%

: 2-(4-isopropylphenyl)-1,3-dithiane

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With 1,3,5-trichloro-2,4,6-triazine; dimethyl sulfoxide In dichloromethane at 20℃; for 1h;	94%

: 23229-31-4
2-(4-isopropylphenyl)-1,3-dithiolane

: 122-03-2
(4-isopropylbenzaldehyde)

Conditions

Conditions	Yield
With 1,3,5-trichloro-2,4,6-triazine; dimethyl sulfoxide In dichloromethane at 20℃; for 2.45h;	93%
With Oxone; potassium bromide In water; acetonitrile at 20℃; for 0.333333h;	92%
With iodosylbenzene In dichloromethane at 20℃; for 0.25h;	91%

4-Isopropylbenzaldehyde Chemical Properties

Chemistry informtion about Cumaldehyde (CAS NO.122-03-2) is:
IUPAC Name: 4-Propan-2-Ylbenzaldehyde
Synonyms: 4-(1-Methylethyl)-Benzaldehyd ; 4-(1-Methylethyl)Benzaldehyde ; 4-(1-Methylethyl)-Benzaldehyde ; 4-(2-Propyl)Benzaldehyde ; 4-Ipr-Benzaldehyde ; Benzaldehyde, P-Isopropyl- ; Cumal ; Cumic Aldehyde
Product Categories: Benzene derivatives ; Aromatic Aldehydes & Derivatives (substituted)
Molecular Formula: C₁₀H₁₂O
Molecular Weight: 148.2
EINECS: 204-516-9
Density: 0.98 g/cm³
Flash Point: 93.3 °C
Boiling Point: 236.1 °C at 760 mmHg
Vapour Pressure: 0.0482 mmHg at 25°C
Enthalpy of Vaporization: 47.29 kJ/mol
Refractive Index: n20/D 1.529(lit.)
FEMA: 2341
Water Solubility: insoluble
Sensitive: Air Sensitive
Merck: 14,2621
BRN: 636547
Following is the molecular structure of Cumaldehyde (CAS NO.122-03-2) is:

4-Isopropylbenzaldehyde Uses

Cumaldehyde (CAS NO.122-03-2) is used in as an aroma for perfumes.Cuminaldehyde is a constituent of the essential oils of eucalyptus, myrrh, cassia, cumin and others.

4-Isopropylbenzaldehyde Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	oral	2400mg/kg (2400mg/kg)		Biochemical Journal. Vol. 34, Pg. 1196, 1940.
rabbit	LD50	skin	2800mg/kg (2800mg/kg)		Food and Cosmetics Toxicology. Vol. 12, Pg. 395, 1974.
rat	LD50	oral	1390mg/kg (1390mg/kg)	behavioral: somnolence (general depressed activity) gastrointestinal: ulceration or bleeding from stomach liver: other changes	Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964.

4-Isopropylbenzaldehyde Consensus Reports

Reported in EPA TSCA Inventory.

4-Isopropylbenzaldehyde Safety Profile

Moderately toxic by ingestion and skin contact. A skin irritant. Combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ALDEHYDES.
Hazard Codes:
Harmful Xn
Risk Statements:
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements:
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S37/39:Wear suitable gloves and eye/face protection.
WGK Germany: 2
RTECS: CU7000000
HS Code: 29122900

4-Isopropylbenzaldehyde Specification

Cumaldehyde (CAS NO.122-03-2) is a natural organic compound with clear colorless to yellow liquid.

Product Name

4-Isopropylbenzaldehyde

Synthetic route

4-Isopropylbenzaldehyde Chemical Properties

4-Isopropylbenzaldehyde Uses

4-Isopropylbenzaldehyde Toxicity Data With Reference

4-Isopropylbenzaldehyde Consensus Reports

4-Isopropylbenzaldehyde Safety Profile

4-Isopropylbenzaldehyde Specification

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