4-Methoxybenzenesulfonyl chloride supplier

Name
4-Methoxybenzenesulfonyl chloride
EINECS 202-692-1
CAS No. 98-68-0
Article Data80
CAS DataBase
Density 1.376 g/cm³
Solubility decomposes with water
Melting Point 39-42 °C(lit.)
Formula C₇H₇ClO₃S
Boiling Point 315.6 °C at 760 mmHg
Molecular Weight 206.65
Flash Point 144.7 °C
Transport Information UN 3261 8/PG 2
Appearance white to beige crystalline solid
Safety 26-36/37/39-45-28-27
Risk Codes 34-29
Molecular Structure
Hazard Symbols C
Synonyms Benzenesulfonylchloride, p-methoxy- (6CI,7CI,8CI);4-Methoxybenzene-1-sulfonyl chloride;4-Methoxybenzenesulfonic acid chloride;4-Methoxyphenylsulphonyl chloride;NSC 403292;p-Anisylsulfonyl chloride;p-Methoxybenzenesulfonyl chloride;p-Methoxyphenylsulfonyl chloride;
PSA 51.75000
LogP 2.70350

Synthetic route

: 696-63-9
4-Methoxybenzenethiol

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With N,N,N',N'-tetrachlorobenzene-1,3-disulphonamide; tetrabutyl-ammonium chloride; water In acetonitrile at 0 - 20℃; for 0.333333h;	99%
With trichloroisocyanuric acid; water In acetonitrile at 0 - 20℃; for 0.333333h;	99%
With thionyl chloride; dihydrogen peroxide In water; acetonitrile at 25℃; for 0.0166667h;	98%

: methylthiocarbamic acid S-(4-methoxyphenyl)ester

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With hydrogenchloride; N-chloro-succinimide In acetonitrile at 10℃;	98.1%

: 60787-31-7
S-(4-methoxyphenyl) ethanethioate

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With hydrogenchloride; N-chloro-succinimide In acetonitrile at 10℃;	97.7%

: 5335-87-5
4,4'-dimethoxyphenyl disulfide

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With dihydrogen peroxide; zirconium(IV) chloride In water; acetonitrile at 25℃; for 0.0166667h;	96%
With dihydrogen peroxide; trichlorophosphate In water at 25℃; for 0.5h; Micellar solution;	95%
With 1,3-dichloro-5,5-dimethylhydantoin; acetic acid In dichloromethane; water at 0 - 20℃; Inert atmosphere;	92%

: 5857-42-1
4-methoxybenzenesulfonic acid

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With 2,2,4,4,6,6-hexachloro-1,3,5-triaza-2,4,6-triphosphorine; potassium chloride at 25℃; for 0.0333333h; Neat (no solvent);	94%

: 100-66-3
methoxybenzene

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With sulfuryl dichloride; sulfuric acid In N,N-dimethyl-formamide	88%
With chlorosulfonic acid at 0 - 5℃;	71.32%
With chlorosulfonic acid at 0 - 5℃;	71.42%

: 26905-24-8
1-benzylsulfanyl-4-methoxy-benzene

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With 1,3-dichloro-5,5-dimethylhydantoin; acetic acid In dichloromethane; water at 0 - 5℃; Inert atmosphere;	86%

: 24197-73-7
S-4-methoxyphenyl benzothioate

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With trichloroisocyanuric acid; benzyltrimethylammonium chloride; sodium carbonate In water; acetonitrile at 0℃; for 0.333333h;	81%

: 459-64-3
4-methoxybenzenediazonium tetrafluoroborate

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With thionyl chloride; tris(bipyridine)ruthenium(II) dichloride hexahydrate In water; acetonitrile at 20℃; for 20h; Concentration; Sealed tube; Irradiation;	71%

: 696-63-9
4-Methoxybenzenethiol

: 127-65-1
chloroamine-T

A: N-chloro-N-(4-methylbenzenesulfonyl)-4-methoxybenzenesulfinamide

B: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With N-chloro-succinimide In water; acetonitrile at 35℃; for 0.25h;	A 70% B 27%

...Expand

: 104-94-9
4-methoxy-aniline

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
Stage #1: 4-methoxy-aniline With tris(bipyridine)ruthenium(II) dichloride hexahydrate; isopentyl nitrite In acetonitrile at 20℃; for 0.0833333h; Sealed tube; Stage #2: With thionyl chloride In water; acetonitrile at 20℃; for 20h; Irradiation;	63%
Stage #1: 4-methoxy-aniline With hydrogenchloride; acetic acid Stage #2: With sodium nitrite In water at -10 - -5℃; for 0.75h; Stage #3: With hydrogenchloride; sulfur dioxide; acetic acid; copper(l) chloride In water at 10℃; for 0.5h;	27%
With tert.-butylnitrite; sulfur dioxide; N-benzyl-N,N,N-triethylammonium chloride; ethylene glycol; copper dichloride In dichloromethane; acetonitrile at 0 - 20℃; Automated synthesizer;
Stage #1: 4-methoxy-aniline With tetrafluoroboric acid; tert.-butylnitrite In ethanol; water at 0 - 20℃; for 1h; Stage #2: With 6,6'-dimethyl-2,2'-bipyridine; 1,4-diazabicyclo [2.2.2] octane-1,4-diium-1,4-disulfinate; potassium chloride; copper dichloride In acetonitrile at 20℃; for 12h; Sealed tube; Inert atmosphere;	50 mg

: 7790-94-5
chlorosulfonic acid

: 100-66-3
methoxybenzene

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
In dichloromethane for 2h;	60%

: 102-96-5
(2-nitroethenyl)benzene

: 4346-59-2
para-methoxyphenyldiazonium chloride

A: 56129-62-5
4-(4-methoxyphenylsulfonyl)-1-phenyl-2-nitroethane

B: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With sulfur dioxide In acetic acid; acetone	A 30% B n/a

...Expand

: 5153-67-3
nitrostyrene

: 4346-59-2
para-methoxyphenyldiazonium chloride

A: 56129-62-5
4-(4-methoxyphenylsulfonyl)-1-phenyl-2-nitroethane

B: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With sulfur dioxide In acetic acid; acetone at 15 - 20℃;	A 30% B n/a

...Expand

: 16475-29-9
phenylchlorosulfate

: 5720-07-0
4-methoxyphenylboronic acid

A: 62141-81-5
4-methoxybenzolsulfonsaeure-phenylester

B: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With t-BuBrettPhos; palladium diacetate; potassium carbonate In toluene at 75℃; for 12h; Reagent/catalyst; Suzuki-Miyaura Coupling;	A 15% B 22%

...Expand

: 4346-59-2
para-methoxyphenyldiazonium chloride

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With sulfur dioxide; copper(l) chloride

: 104-92-7
1-bromo-4-methoxy-benzene

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
Yield given. Multistep reaction;
Stage #1: 1-bromo-4-methoxy-benzene With iodine; magnesium In tetrahydrofuran for 1h; Heating; Stage #2: With sulfur dioxide In tetrahydrofuran at -40℃; for 0.5h; Stage #3: With sulfuryl dichloride In tetrahydrofuran at -40 - 20℃;

: 70744-47-7
(p-methoxyphenyl)tri-n-butylstannane

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With sulfuryl dichloride at 20℃; for 4h;

: Trifluoro-acetic acid 4-methoxy-phenylsulfanylmethyl ester

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With chlorine; acetic acid In dichloromethane Yield given;

potassium salt of/the/ p-anisolesulfonic acid: potassium salt of/the/ p-anisolesulfonic acid

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With phosphorus pentachloride at 100℃;

sodium-<4-methoxy-benzene sulfonate-(1)>: sodium-<4-methoxy-benzene sulfonate-(1)>

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With phosphorus pentachloride

: 696-62-8
para-iodoanisole

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: copper(l) iodide; 1,10-Phenanthroline; N-ethyl-N,N-diisopropylamine / toluene / 16 h / Reflux 2: trichloroisocyanuric acid; benzyltrimethylammonium chloride; sodium carbonate / water; acetonitrile / 0.33 h / 0 °C View Scheme

: 772-80-5
4-methylphenyl chlorosulfate

: 1447963-66-7
2,6-diisopropylphenyl chlorosulfate

: 5720-07-0
4-methoxyphenylboronic acid

A: 106-44-5
p-cresol

B: 2078-54-8
2,6-diisopropylphenol

C: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
Stage #1: 4-methoxyphenylboronic acid With C43H43NO3PPdS; sodium carbonate In [(2)H6]acetone at 20℃; Inert atmosphere; Sealed tube; Stage #2: 4-methylphenyl chlorosulfate; 2,6-diisopropylphenyl chlorosulfate In [(2)H6]acetone at 50℃; for 10h;	A 43 %Spectr. B 72 %Spectr. C 97 %Spectr.

...Expand

: 772-80-5
4-methylphenyl chlorosulfate

: 5720-07-0
4-methoxyphenylboronic acid

A: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

B: 274251-50-2
p-tolylboric acid

Conditions

Conditions	Yield
With C43H43NO3PPdS; sodium carbonate In [(2)H6]acetone at 60℃; for 6h;

...Expand

: 5720-07-0
4-methoxyphenylboronic acid

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With phenylchlorosulfate; C43H43NO3PPdS; sodium carbonate In acetone at 50℃; for 12h; Inert atmosphere;

: 108-95-2
phenol

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: potassium hydroxide / methanol / 5 h / 0 - 60 °C / Inert atmosphere 2: dichloromethane / 2 h View Scheme
Multi-step reaction with 2 steps 1: potassium hydroxide / methanol / 5 h / 0 - 20 °C / Inert atmosphere 2: chlorosulfonic acid / dichloromethane / -5 °C View Scheme

: 6140-09-6
sodium 4-methoxy-benzenesulfonate

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With thionyl chloride; N,N-dimethyl-formamide for 4h; Reflux;

: 825-90-1
sodium p-hydroxybenzenesulfonate

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: sodium carbonate / methanol / Reflux 2: thionyl chloride; N,N-dimethyl-formamide / 4 h / Reflux View Scheme

: 1129-26-6
4-methoxybenzene sulfonamide

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

Conditions

Conditions	Yield
With pyrylium tetrafluoroborate; magnesium chloride In tert-butyl alcohol at 60℃; for 3h;

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 4547-64-2
4-methoxybenzenesulfonyl azide

Conditions

Conditions	Yield
With sodium azide In water; acetone at 0 - 20℃; for 11h; Sealed tube;	100%
With sodium azide In water; acetone	97%
With sodium azide; tributyl methyl phsophonium chloride immobibized on polystyrene matrix In 1,2-dichloro-ethane at 45℃; for 4h;	96%

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 1950-68-1
4-methoxybenzenesulfonyl hydrazide

Conditions

Conditions	Yield
With hydrazine hydrate In tetrahydrofuran at 0℃;	100%
With hydrazine hydrate In tetrahydrofuran at 5℃; for 0.5h;	95%
With hydrazine hydrate In tetrahydrofuran at 5℃; for 0.5h; Cooling with ice;	95%

: 83595-58-8
Tr-Trp-OBzl

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 83595-60-2
Tr-Trp(Mbs)-OBzl

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide Ambient temperature; 1.) 2 h, 2.) 15 h;	100%

: 5344-90-1
2-Aminobenzyl alcohol

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 601481-95-2
N-(2-hydroxymethylphenyl)-4-methoxybenzenesulfonamide

Conditions

Conditions	Yield
With pyridine In dichloromethane at 20℃; for 3h;	100%
With pyridine In dichloromethane at 20℃;
With pyridine In dichloromethane Reflux;
With pyridine In dichloromethane at 0 - 20℃; for 2h;
With pyridine In dichloromethane at 20℃; for 4h;

: 930121-05-4
3,4,5-triacetoxy-6-[4-(3-amino-pyridin-2-ylamino)-phenoxy]-tetrahydro-pyran-2-carboxylic acid methyl ester

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 930121-03-2
3,4,5-triacetoxy-6-{4-[3-(4-methoxy-benzenesulfonylamino)-pyridin-2-ylamino]-phenoxy}-tetrahydro-pyran-2-carboxylic acid methyl ester

Conditions

Conditions	Yield
With pyridine	100%

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 107-11-9
1-amino-2-propene

: 34954-40-0
N-allyl-4-methoxybenzenesulfonamide

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0 - 20℃; for 19h; Inert atmosphere;	100%
With triethylamine In dichloromethane at 0 - 20℃;	96%
With sodium hydroxide In diethyl ether; water at 20℃; for 5h; Schotten-Baumann reaction;	73%

: 4-(4-aminomethylbenzyl)-nitrobenzene

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 4-[4-(4-methoxyphenyl)sulfonylaminomethylbenzyl]-nitrobenzene

Conditions

Conditions	Yield
With triethylamine In dichloromethane	100%

: 1161026-84-1
tert-butyl (2S,3R)-3-hydroxy-4-[((S)-5-oxopyrrolidin-2-yl)-methylamino]-1-phenylbutan-2-ylcarbamate

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 1053613-59-4
tert-butyl (2S,3R)-3-hydroxy-4-(4-methoxy-N-(((S)-5-oxopyrrolidin-2-yl)methyl)phenylsulfonamido)-1-phenylbutan-2-ylcarbamate

Conditions

Conditions	Yield
With sodium hydrogencarbonate In dichloromethane; water for 12h;	100%

: 41661-47-6
piperidin-4-one

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 196085-08-2
1-(4-methoxybenzenesulfonyl)-4-piperidone

Conditions

Conditions	Yield
With pyridine at 20℃; for 18h;	100%

: C21H35NO12

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 1356387-27-3
methyl 2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl-(1->4)-6-deoxy-6-(4-methoxyphenylsulfonylamino)-2,3-di-O-methyl-α-D-galactopyranoside

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0 - 20℃; Inert atmosphere;	100%

: 6310-21-0
2-(1,1-dimethylethyl)-benzenamine

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: N-(2-(tert-butyl)phenyl)-4-methoxybenzenesulfonamide

Conditions

Conditions	Yield
With pyridine In dichloromethane at 0 - 20℃; for 18h; Inert atmosphere;	100%

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 6462-50-6
sodium 4-methoxybenzenesulfinate

Conditions

Conditions	Yield
With sodium hydrogencarbonate; sodium sulfite In tetrahydrofuran; water at 0 - 20℃;	99.9%
With sodium hydrogencarbonate; sodium sulfite In water at 80℃; for 4h;	92%
With sodium hydrogencarbonate; sodium sulfite In water at 80℃; for 4h;	92%

: 536-90-3
m-Anisidine

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 169945-40-8
4-methoxy-N-(3-methoxyphenyl)benzenesulfonamide

Conditions

Conditions	Yield
Stage #1: m-Anisidine With pyridine In dichloromethane for 0.166667h; Stage #2: 4-methoxy-phenyl-sulphonyl chloride In dichloromethane for 0.25h;	99.6%
	2.50 g (99.7%)
In dichloromethane at 20℃; for 3h; Inert atmosphere;

: 110-85-0
piperazine

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 121751-67-5
1‐(4‐methoxyphenylsulfonyl)piperazine

Conditions

Conditions	Yield
In dichloromethane at 0℃;	99%
In dichloromethane at 0 - 20℃;	96%
Stage #1: piperazine; 4-methoxy-phenyl-sulphonyl chloride With pyridine In dichloromethane at 20℃; for 15h; Stage #2: With hydrogenchloride In water	88%

: 13141-38-3
2-phenylethynylaniline

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 946161-94-0
4-methoxy-N-(2-(phenylethynyl)phenyl)benzenesulfonamide

Conditions

Conditions	Yield
With pyridine In dichloromethane at 20℃; for 19.5h;	99%
With pyridine In dichloromethane at 0 - 20℃;
With pyridine In chloroform at 20℃;
With pyridine In dichloromethane at 0 - 25℃; for 72h; Inert atmosphere; Schlenk technique;	0.96 g

: 854539-15-4
3-methyl-1-[3-(4-methylbenzyl)-[1,2,4]thiadiazol-5-yl]piperazine

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 1-[4-methoxyphenylsulfonyl]-4-[3-(4-methylbenzyl)-1,2,4-thiadiazol-5-yl]-2-methylpiperazine

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 20℃; for 4h;	99%
With triethylamine In dichloromethane at 20℃; for 4h;	99%

: 703-80-0
3-acetylindole

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 3-acetyl-1-((4-methoxyphenyl)sulfonyl)indole

Conditions

Conditions	Yield
Stage #1: 3-acetylindole With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.5h; Inert atmosphere; Stage #2: 4-methoxy-phenyl-sulphonyl chloride In N,N-dimethyl-formamide at 20℃; Inert atmosphere; Cooling with ice;	99%
With potassium carbonate In acetone at 20℃; for 12h; Inert atmosphere;

: 42925-75-7
1-(1H-indol-3-yl)hexan-1-one

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 1352537-20-2
C21H23NO4S

Conditions

Conditions	Yield
Stage #1: 1-(1H-indol-3-yl)hexan-1-one With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.5h; Inert atmosphere; Stage #2: 4-methoxy-phenyl-sulphonyl chloride In N,N-dimethyl-formamide at 20℃; Inert atmosphere; Cooling with ice;	99%

: 42925-74-6
1-(1H-indol-3-yl)pentan-1-one

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 1352537-18-8
C20H21NO4S

Conditions

Conditions	Yield
Stage #1: 1-(1H-indol-3-yl)pentan-1-one With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.5h; Inert atmosphere; Stage #2: 4-methoxy-phenyl-sulphonyl chloride In N,N-dimethyl-formamide at 20℃; Inert atmosphere; Cooling with ice;	99%

: 7-benzyloxy-5-bromoindoline

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 7-benzyloxy-5-bromo-1-(4-methoxyphenylsulfonyl)indoline

Conditions

Conditions	Yield
With pyridine at 95℃; Inert atmosphere;	99%

: C12H19N3O4

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: C19H25N3O7S

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0 - 20℃; for 16h;	99%

: 769-92-6
4-tert-Butylaniline

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: N-(4-(tert-butyl)phenyl)-4-methoxybenzenesulfonamide

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0 - 20℃; for 16h; Inert atmosphere;	99%

: 3959-05-5
2-bromobenzylamine

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: N-(2-bromobenzyl)-4-methoxybenzenesulfonamide

Conditions

Conditions	Yield
With pyridine at 90℃; Inert atmosphere;	99%

: 78537-14-1
D-Ser(O-t-Bu) methyl ester hydrochloride

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: C15H23NO6S

Conditions

Conditions	Yield
Stage #1: D-Ser(O-t-Bu) methyl ester hydrochloride With triethylamine In dichloromethane at 0 - 20℃; for 0.5h; Stage #2: 4-methoxy-phenyl-sulphonyl chloride In dichloromethane at 0 - 20℃; for 4h;	99%
Stage #1: D-Ser(O-t-Bu) methyl ester hydrochloride With triethylamine In dichloromethane at 0 - 20℃; for 0.5h; Stage #2: 4-methoxy-phenyl-sulphonyl chloride With dmap In dichloromethane at 0 - 20℃; for 4h;	99%

: 27532-96-3
glycine tert-butyl ester hydrochloride

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: tert-butyl ((4-methoxyphenyl)sulfonyl)glycinate

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 16h; Inert atmosphere;	99%
With pyridine at 20℃; for 4h;	54%

: 6-((4S,5S)-4,5-diphenyl-4,5-dihydro-1H-imidazol-2-yl)-2,2′-bipyridine

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 6-((4S,5S)-1-((4-methoxyphenyl)sulfonyl)-4,5-diphenyl-4,5-dihydro-1H-imidazol-2-yl)-2,2′-bipyridine

Conditions

Conditions	Yield
With dmap In dichloromethane at 0℃; for 4h; Schlenk technique;	99%

: 4-((4-methoxyphenyl)ethynyl)naphthalen-1-amine

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 4-methoxy-N-(4-((4-methoxyphenyl)ethynyl)naphthalen-1-yl)benzenesulfonamide

Conditions

Conditions	Yield
With pyridine Sealed tube;	99%
With pyridine at 20℃; for 18h;	99%

: (R)-N-(5,6-dimethoxybenzo[d]thiazol-2-yl)pyrrolidine-2-carboxamide hydrochloride

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: (R)-N-(5,6-dimethoxybenzo[d] thiazol-2-yl)-1-((4-methoxyphenyl)sulfonyl)pyrrolidine-2-carboxamide

Conditions

Conditions	Yield
With pyridine In acetonitrile for 14h;	99%

: methyl (R,E)-4-(3-amino-1-benzyl-5-bromo-2-oxoindolin-3-yl)but-2-enoate

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: methyl (R,E)-4-[1-benzyl-5-bromo-3-(4-methoxybenzenesulfonamide)-2-oxoindolin-3-yl]but-2-enoate

Conditions

Conditions	Yield
With pyridine In chloroform at 0 - 20℃; for 26h; Inert atmosphere;	99%

4-Methoxybenzenesulfonyl chloride Chemical Properties

IUPAC Name: 4-methoxybenzenesulfonyl chloride
Empirical Formula: C₇H₇ClO₃S
Molecular Weight: 206.6467g/mol
EINECS: 202-692-1
Structure of Benzenesulfonylchloride, 4-methoxy- (CAS NO.98-68-0):

Index of Refraction: 1.535
Molar Refractivity: 46.76 cm³
Molar Volume: 150 cm³
Polarizability: 18.53×10^-24cm³
Surface Tension: 41.4 dyne/cm
Density: 1.376 g/cm³
Flash Point: 144.7 °C
Enthalpy of Vaporization: 53.47 kJ/mol
Melting Point: 39-42 °C(lit.)
Boiling Point: 315.6 °C at 760 mmHg
Vapour Pressure: 0.0008 mmHg at 25°C
Water Solubility: decomposes
Sensitive: Moisture Sensitive
Product Categories: Phenyls & Phenyl-Het;Sulphonyl Chlorides;Benzene derivates;Protection & Derivatization Reagents (for Synthesis);Synthetic Organic Chemistry;Phenyls & Phenyl-Het;Sulphonyl Chlorides;Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds
Canonical SMILES: COC1=CC=C(C=C1)S(=O)(=O)Cl
InChI: InChI=1S/C7H7ClO3S/c1-11-6-2-4-7(5-3-6)12(8,9)10/h2-5H,1H3
InChIKey: DTJVECUKADWGMO-UHFFFAOYSA-N

4-Methoxybenzenesulfonyl chloride Safety Profile

Hazard Codes: Corrosive C
Risk Statements: 34-29
R34:Causes burns.
R29:Contact with water liberates toxic gas.
Safety Statements: 26-36/37/39-45-28-27
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S28:After contact with skin, wash immediately with plenty of soap-suds.
S27:Take off immediately all contaminated clothing.
RIDADR: UN 3261 8/PG 2
WGK Germany: 3
F: 10-21
Hazard Note: Corrosive/Moisture Sensitive
HazardClass: 8
PackingGroup: II

4-Methoxybenzenesulfonyl chloride Specification

Benzenesulfonylchloride, 4-methoxy- , its cas register number is 98-68-0. It also can be called 4-Methoxybenzenesulphonyl chloride . Benzenesulfonylchloride, 4-methoxy- (CAS NO.98-68-0) is a white to beige crystalline solid.

Product Name

4-Methoxybenzenesulfonyl chloride

Synthetic route

4-Methoxybenzenesulfonyl chloride Chemical Properties

4-Methoxybenzenesulfonyl chloride Safety Profile

4-Methoxybenzenesulfonyl chloride Specification

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