4-Methoxyphenethylamine supplier

Name
4-Methoxyphenethylamine
EINECS 200-245-5
CAS No. 55-81-2
Article Data85
CAS DataBase
Density 1.008 g/cm³
Solubility
Melting Point 249-251°C
Formula C₉H₁₃NO
Boiling Point 255.2 °C at 760 mmHg
Molecular Weight 151.208
Flash Point 105.3 °C
Transport Information UN 2735
Appearance clear colorless to slightly yellow liquid
Safety 26-36/37/39-45
Risk Codes 34
Molecular Structure
Hazard Symbols C
Synonyms Phenethylamine,p-methoxy- (6CI,8CI);2-(4-Methoxyphenyl)ethanamine;2-(4-Methoxyphenyl)ethylamine;2-(p-Methoxyphenyl)ethylamine;4-Methoxy-b-phenethylamine;4-Methoxy-b-phenylethylamine;4-Methoxybenzeneethanamine;4-Methoxyphenethylamine;4-Methoxyphenylethylamine;Homoanisylamine;NSC 43687;O-Methyltyramine;Tyramine, O-methyl-;p-Methoxyphenethylamine;
PSA 35.25000
LogP 1.89670

Synthetic route

: 198756-72-8
benzyl 4-methoxyphenethylcarbamate

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen In methanol at 20℃; for 1h;	100%

: 104-47-2
p-methoxybenzylnitrile

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With aluminum (III) chloride; lithium aluminium tetrahydride In diethyl ether at 0 - 20℃;	96%
With lithium borohydride; diisopropopylaminoborane In tetrahydrofuran for 18h; Reflux;	94%
With [Ru(H)(BH4)(CO)(PPh3)(3-(di-tert-butylphosphino)-N-((1-methyl-1H-imidazol-2 yl)methyl)propylamine)]; hydrogen In isopropyl alcohol at 70℃; for 3h; Inert atmosphere; Autoclave;	94%

: 31236-71-2
lysichitalexin

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With samarium diiodide; water; isopropylamine In tetrahydrofuran	96%

: N-[2-(4-methoxy-phenyl)-ethyl]-2-nitro-benzenesulfonamide

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With potassium carbonate; thiophenol In acetonitrile at 50℃;	95%

: 1258181-22-4
C12H14Cl3NO3

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
Stage #1: C12H14Cl3NO3 With chloro-trimethyl-silane; mischmetal In tetrahydrofuran for 2h; Inert atmosphere; Reflux; Stage #2: With water In tetrahydrofuran for 0.0833333h; Alkaline conditions;	87%

: 3179-10-0
1-methoxy-4-(2-nitro-vinyl)-benzene

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With hydrogenchloride; hydrogen; acetic acid; palladium on activated charcoal for 1h;	71%
With hydrogen; carbon palladium at 85℃; under 37503 Torr;	70%
(catalytic hydrogenation);

: 91247-71-1
2-4-methoxyphenylethylcarbamic acid methyl ester

A: 22246-04-4
7-methoxy-3,4-dihydro-2H-isoquinolin-1-one

B: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With PPA at 145℃; for 0.166667h;	A 59% B 30%

: 25413-27-8
3-(4-methoxy-phenyl)propionamide

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With sodium hydroxide; bromine In water at 70 - 80℃; for 0.25h;	53%
With sodium hypobromide
With alkaline sodium hypochlorite

: 141666-92-4
4-methyl-N-[2-(4-methoxyphenyl)ethyl]benzenesulfonamide

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With titanium tetrachloride In tetrahydrofuran for 2.5h; Heating;	40%

: 3179-10-0, 5576-97-6
(E)-1-methoxy-4-(2-nitrovinyl)benzene

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With samarium diiodide; water; isopropylamine In tetrahydrofuran	36%
With sulfuric acid; palladium; acetic acid Hydrogenation;
bei der elektrochemischen Reduktion;
With lithium aluminium tetrahydride

: 151-56-4
ethyleneimine

: 100-66-3
methoxybenzene

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With aluminium trichloride

: 637-69-4
4-Methoxystyrene

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With chloroform; nitrosylchloride Hydrieren des Reaktionsprodukts an Raney-Nickel in Methanol;
Multi-step reaction with 3 steps 1: NOCl, HCl / diethyl ether 2: Et3N / diethyl ether 3: LiAlH4 / diethyl ether View Scheme
With D-Glucose; ammonia; oxygen In aq. phosphate buffer at 30℃; for 10h; Green chemistry; regioselective reaction;
Multi-step reaction with 3 steps 1: oxygen; styrene monooxygenase / Enzymatic reaction 2: styrene oxide isomerase / Enzymatic reaction 3: ammonia; ω-transaminase; L-alanine dehydrogenase / Enzymatic reaction View Scheme

: 33646-40-1
4-methoxymandelonitrile

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With hydrogenchloride; ethanol; platinum Hydrogenation;

: 1929-29-9
3-(4-methoxyphenyl)propanoic acid

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With sodium azide; chloroform; sulfuric acid
Multi-step reaction with 2 steps 1: thionyl chloride; chloroform / nachfolgend Behandlung mit Natriumhydroxyd in Ammoniak 2: alkaline sodium hypochlorite View Scheme
Multi-step reaction with 3 steps 1: chloroform; PCl5 2: diethyl ether; NH3 3: bromine; NaOH-solution / 55 °C View Scheme

: 14271-83-1
4-methoxybenzoyl cyanide

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With sulfuric acid; palladium; acetic acid Hydrogenation;

: 3353-51-3
2-(4-methoxyphenyl)acetaldehyde oxime

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With sulfuric acid; palladium; acetic acid Hydrogenation;

: 99843-19-3
acetoxy-(4-methoxy-phenyl)-acetonitrile

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With sulfuric acid; palladium; acetic acid Hydrogenation;

: 104-47-2
p-methoxybenzylnitrile

A: 122380-12-5
4-methoxy-N-[2-(4-methoxyphenyl)ethyl]benzeneethanamine

B: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With nickel Hydrogenation;

: 18217-00-0
1-(2-Chloroethyl)-4-methoxybenzene

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With ammonia
With ethanol; ammonia at 100℃;

: 2742-79-2
Bis-(β-nitroso-4-methoxy-styrol)

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In diethyl ether

: 169614-59-9
2-[2-(4-methoxyphenyl)ethyl]-1H-isoindole-1,3(2H)-dione

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With hydrazine hydrate In methanol at 70℃;

: 86423-53-2
[2-(4-Methoxy-phenyl)-ethyl]-phosphoramidic acid diethyl ester

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With hydrogenchloride at 80 - 85℃; for 1.5h; Yield given;

2-amino-1-<4-methoxy-phenyl>-ethanone-(1)-hydrochloride: 2-amino-1-<4-methoxy-phenyl>-ethanone-(1)-hydrochloride

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
With sulfuric acid; palladium; acetic acid Hydrogenation;

4-methoxy-phenylacetaldoxime: 4-methoxy-phenylacetaldoxime

: 55-81-2
4-Methoxyphenethylamine

: 7664-93-9
sulfuric acid

: 3179-10-0, 5576-97-6
(E)-1-methoxy-4-(2-nitrovinyl)benzene

: 64-19-7
acetic acid

palladium: palladium

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
Hydrogenation;

...Expand

: 7664-93-9
sulfuric acid

: 14271-83-1
4-methoxybenzoyl cyanide

: 64-19-7
acetic acid

palladium: palladium

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
Hydrogenation;

...Expand

: 64-17-5
ethanol

: 3179-10-0, 5576-97-6
(E)-1-methoxy-4-(2-nitrovinyl)benzene

platinum: platinum

: 55-81-2
4-Methoxyphenethylamine

Conditions

Conditions	Yield
Hydrogenation;

...Expand

: 25413-27-8
3-(4-methoxy-phenyl)propionamide

: 7726-95-6
bromine

: furan-2,3,5(4H)-trione pyridine (1:1)

: 55-81-2
4-Methoxyphenethylamine

...Expand

: 3353-51-3
2-(4-methoxyphenyl)acetaldehyde oxime

sodium amalgam: sodium amalgam

alcoholic glacial acetic acid: alcoholic glacial acetic acid

: 55-81-2
4-Methoxyphenethylamine

...Expand

: 55-81-2
4-Methoxyphenethylamine

: 79-22-1
methyl chloroformate

: 91247-71-1
2-4-methoxyphenylethylcarbamic acid methyl ester

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine Inert atmosphere; Cooling with ice;	100%
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃;	99%
With triethylamine In tetrahydrofuran for 24h; Ambient temperature;	95%

: 55-81-2
4-Methoxyphenethylamine

: 79-04-9
chloroacetyl chloride

: 17639-50-8
2-(4-methoxyphenyl)ethan-1-aminechloroacetate

Conditions

Conditions	Yield
With potassium carbonate In dichloromethane Ambient temperature;	100%
With triethylamine In dichloromethane at 0 - 20℃; for 6h; Reflux;	85%
With triethylamine In dichloromethane at 0 - 20℃; for 4h;	76%

: 55-81-2
4-Methoxyphenethylamine

: 79-11-8
chloroacetic acid

4-formyl-3,5-dimethoxyphenoxy-Merrifield resin: 4-formyl-3,5-dimethoxyphenoxy-Merrifield resin

: 17639-50-8
2-(4-methoxyphenyl)ethan-1-aminechloroacetate

Conditions

Conditions	Yield
Stage #1: 4-Methoxyphenethylamine; 4-formyl-3,5-dimethoxyphenoxy-Merrifield resin With sodium tris(acetoxy)borohydride In acetic acid; N,N-dimethyl-formamide at 20℃; for 69h; Solid phase reaction; reductive amination; Stage #2: chloroacetic acid With benzotriazol-1-ol; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 20℃; for 15h; Solid phase reaction; acylation; Stage #3: With dimethylsulfide; water; trifluoroacetic acid In dichloromethane at 20℃; for 15h; Solid phase reaction; cleavage of amide;	100%

Yield

Stage #1: 4-Methoxyphenethylamine; 4-formyl-3,5-dimethoxyphenoxy-Merrifield resin With sodium tris(acetoxy)borohydride In acetic acid; N,N-dimethyl-formamide at 20℃; for 69h; Solid phase reaction; reductive amination;
Stage #2: chloroacetic acid With benzotriazol-1-ol; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 20℃; for 15h; Solid phase reaction; acylation;
Stage #3: With dimethylsulfide; water; trifluoroacetic acid In dichloromethane at 20℃; for 15h; Solid phase reaction; cleavage of amide;

100%

...Expand

: 55-81-2
4-Methoxyphenethylamine

: 107-92-6
butyric acid

4-formyl-3,5-dimethoxyphenoxy-Merrifield resin: 4-formyl-3,5-dimethoxyphenoxy-Merrifield resin

: N-butanoyl-2-(4-methoxyphenyl)ethanamine

Conditions

Conditions	Yield
Stage #1: 4-Methoxyphenethylamine; 4-formyl-3,5-dimethoxyphenoxy-Merrifield resin With sodium tris(acetoxy)borohydride In acetic acid; N,N-dimethyl-formamide at 20℃; for 69h; Solid phase reaction; reductive amination; Stage #2: butyric acid With benzotriazol-1-ol; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 20℃; for 15h; Solid phase reaction; acylation; Stage #3: With dimethylsulfide; water; trifluoroacetic acid In dichloromethane at 20℃; for 15h; Solid phase reaction; cleavage of amide;	100%

Yield

Stage #1: 4-Methoxyphenethylamine; 4-formyl-3,5-dimethoxyphenoxy-Merrifield resin With sodium tris(acetoxy)borohydride In acetic acid; N,N-dimethyl-formamide at 20℃; for 69h; Solid phase reaction; reductive amination;
Stage #2: butyric acid With benzotriazol-1-ol; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 20℃; for 15h; Solid phase reaction; acylation;
Stage #3: With dimethylsulfide; water; trifluoroacetic acid In dichloromethane at 20℃; for 15h; Solid phase reaction; cleavage of amide;

100%

...Expand

: 55-81-2
4-Methoxyphenethylamine

: 350716-60-8
piperidine-1,4-dicarboxylic acid mono-(4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-1,1-dimethylundecyl) ester

: 350717-38-3
4-[2-(4-methoxy-phenyl)-ethylcarbamoyl]-piperidine-1-carboxylic acid 4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-1,1-dimethyl-undecyl ester

Conditions

Conditions	Yield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In chloroform; N,N-dimethyl-formamide at 20℃; for 16h;	100%

: 24424-99-5
di-tert-butyl dicarbonate

: 55-81-2
4-Methoxyphenethylamine

: 121778-75-4
N-(tert-butoxycarbonyl)-2-(4-methoxyphenyl)-ethylamine

Conditions

Conditions	Yield
With guanidine hydrochloride In ethanol at 35 - 40℃; for 0.0166667h;	100%
With sulfonic acid-functionalized nanoporous titania catalyst In neat (no solvent) at 20℃; for 0.266667h; chemoselective reaction;	96%
With triethylamine In dichloromethane at 20℃; for 1h;	96%

: 5-((3-chloro-4-fluorophenylsulfonamido)methyl)picolinic acid

: 55-81-2
4-Methoxyphenethylamine

: 5-[(3-chloro-4-fluorobenzene)sulfonamidomethyl]-N-[2-(4-methoxyphenyl)ethyl] pyridine-2-carboxamide

Conditions

Conditions	Yield
With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; triethylamine In N,N-dimethyl-formamide at 20℃; for 18h;	99.94%

: 108-24-7
acetic anhydride

: 55-81-2
4-Methoxyphenethylamine

: 54815-19-9
N-(4-methoxyphenylethyl)acetamide

Conditions

Conditions	Yield
at 20 - 30℃; for 1h;	99%
With triethylamine In dichloromethane for 2h; Ambient temperature;	86%
With triethylamine In dichloromethane at 20℃;	85%

: 541-41-3
chloroformic acid ethyl ester

: 55-81-2
4-Methoxyphenethylamine

: 136390-01-7
ethyl-N-<2-(4-methoxyphenyl)ethyl>-carbamate

Conditions

Conditions	Yield
With potassium carbonate In tetrahydrofuran at 25℃;	99%
With pyridine In dichloromethane at 0 - 20℃;	99%
With triethylamine In dichloromethane at 0 - 25℃; for 1h;	98.3%

: 56074-20-5
N-((tert-butyloxy)carbonyl)iminodiacetic acid

: 55-81-2
4-Methoxyphenethylamine

: 188625-14-1
N-((tert-butyloxy)carbonyl)-N'-(2-(4-methoxyphenyl)ethyl)iminodiacetic acid monoamide

Conditions

Conditions	Yield
With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 25℃; for 20h; Substitution;	99%

: 55-81-2
4-Methoxyphenethylamine

: 29568-33-0
2-methoxy-5-chlorobenzoyl chloride

: 158751-77-0
5-chloro-2-methoxy-N-(2-(4-methoxyphenyl)ethyl)benzamide

Conditions

Conditions	Yield
With pyridine at 20℃; for 1h;	99%

: 75-15-0
carbon disulfide

: 55-81-2
4-Methoxyphenethylamine

: 2216-94-6
phenylpropynoic acid ethyl ester

: (Z)-5-benzylidene-3-[2-(4-methoxyphenyl)ethyl]-2-thioxo-thiazolidin-4-one

Conditions

Conditions	Yield
Stage #1: carbon disulfide; 4-Methoxyphenethylamine In isopropyl alcohol at 20℃; for 6h; Stage #2: phenylpropynoic acid ethyl ester; tributylphosphine In isopropyl alcohol at 20℃; Further stages.;	99%

...Expand

: 93-40-3
(3,4-Dimethoxyphenyl)acetic acid

: 55-81-2
4-Methoxyphenethylamine

: 13397-02-9
2-(3,4-dimethoxyphenyl)-N-[2-(4-methoxyphenyl)ethyl]acetamide

Conditions

Conditions	Yield
In neat (no solvent) at 150℃; for 0.5h; Microwave irradiation;	99%
In 5,5-dimethyl-1,3-cyclohexadiene for 16h; Reflux; Inert atmosphere;	94%

: 1878-66-6
4-chlorophenylacetic Acid

: 55-81-2
4-Methoxyphenethylamine

: 340218-64-6
2-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)ethyl]acetamide

Conditions

Conditions	Yield
In neat (no solvent) at 150℃; for 0.5h; Microwave irradiation;	99%

: 104-01-8
4-Methoxyphenylacetic acid

: 55-81-2
4-Methoxyphenethylamine

: 41898-71-9
2-(4-methoxyphenyl)-N-[2-(4-methoxyphenyl)ethyl]acetamide

Conditions

Conditions	Yield
In neat (no solvent) at 150℃; for 0.5h; Microwave irradiation;	99%
With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; N-ethyl-N,N-diisopropylamine

: 951-82-6
3,4,5-trimethoxyphenyl acetic acid

: 55-81-2
4-Methoxyphenethylamine

: 1037943-04-6
N-[2-(4-methoxyphenyl)ethyl]-2-(3,4,5-trimethoxyphenyl)acetamide

Conditions

Conditions	Yield
In neat (no solvent) at 150℃; for 0.5h; Microwave irradiation;	99%

: 55-81-2
4-Methoxyphenethylamine

: 581-96-4
2-naphthylacetic acid

: 1037942-89-4
N-[2-(4-methoxyphenyl)ethyl]-2-(naphthalen-2-yl)acetamide

Conditions

Conditions	Yield
In neat (no solvent) at 150℃; for 0.5h; Microwave irradiation;	99%

: 2,5-dioxopyrrolidin-1-yl 2-(diisopropoxyphosphoryl)acetate

: 123-46-6
girard's reagent T

: 55-81-2
4-Methoxyphenethylamine

A: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

B: 1426294-40-7
diisopropyl (2-((4-methoxyphenethyl)amino)-2-oxoethyl)phosphonate

C: C13H29N3O5P(1+)*Cl(1-)

Conditions

Conditions	Yield
Stage #1: 2,5-dioxopyrrolidin-1-yl 2-(diisopropoxyphosphoryl)acetate; 4-Methoxyphenethylamine In dichloromethane at 20℃; for 4h; Stage #2: girard's reagent T In methanol; dichloromethane	A n/a B 99% C n/a

...Expand

: racemic trans-1-(tert-butoxycarbonyl)pyrrolidine-3,4-dicarboxylic acid

: 55-81-2
4-Methoxyphenethylamine

: tert-butyl trans-3,4-bis((4-methoxyphenethyl)carbamoyl)pyrrolidine-1-carboxylate

Conditions

Conditions	Yield
With 2,6-dimethylpyridine; 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 23℃; for 16h; Inert atmosphere;	99%

: 33166-49-3
3,3,3-triphenylpropionyl chloride

: 55-81-2
4-Methoxyphenethylamine

: N-[2-(4-methoxy-phenyl)-ethyl]-3,3,3-triphenyl-propionamide

Conditions

Conditions	Yield
With dmap; triethylamine In dichloromethane at 0 - 20℃; for 48h;	98.9%

: 331-39-5
caffeic acid

: 55-81-2
4-Methoxyphenethylamine

: 7′-(3′,4′-dihydroxyphenyl)-N-[(4-methoxyphenyl)ethyl]propenamide

Conditions

Conditions	Yield
Stage #1: caffeic acid With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide for 0.25h; Cooling with ice; Stage #2: 4-Methoxyphenethylamine In N,N-dimethyl-formamide at 20℃;	98.8%

: 55-81-2
4-Methoxyphenethylamine

: 2373-80-0
3,4-(methylenedioxy)cinnamic acid

: C19H19NO4

Conditions

Conditions	Yield
Stage #1: 3,4-(methylenedioxy)cinnamic acid With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide for 0.25h; Cooling with ice; Stage #2: 4-Methoxyphenethylamine In N,N-dimethyl-formamide at 20℃;	98.4%

: 55-81-2
4-Methoxyphenethylamine

: 67175-79-5
2-(4-methoxycyclohexa-1,4-dienyl)ethylamine

Conditions

Conditions	Yield
With ammonia; sodium In tetrahydrofuran; ethanol at -78℃; Birch reduction;	98%
With ammonia; lithium In tert-butyl alcohol at -78℃; for 6h;	95%
With ammonia; lithium In ethanol at -78℃; for 15h;	94%

: 55-81-2
4-Methoxyphenethylamine

: 98-59-9
p-toluenesulfonyl chloride

: 141666-92-4
4-methyl-N-[2-(4-methoxyphenyl)ethyl]benzenesulfonamide

Conditions

Conditions	Yield
In dichloromethane at 20℃; for 2h; Tosylation;	98%
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 2h;	93%
Stage #1: 4-Methoxyphenethylamine With sodium carbonate In water for 0.5h; pH=8 - 9; Stage #2: p-toluenesulfonyl chloride In water	91%

: 50921-39-6
1-(4-chlorophenyl)cyclobutane-1-carboxylic acid

: 55-81-2
4-Methoxyphenethylamine

: 916923-23-4
1-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)ethyl]cyclobutanecarboxamide

Conditions

Conditions	Yield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 3 - 20℃;	98%

: 2861-28-1
1,3-benzodioxole-5-acetic acid

: 55-81-2
4-Methoxyphenethylamine

: 1395084-65-7
2-(2H-1,3-benzodioxol-5-yl)-N-[2-(4-methoxyphenyl)ethyl]acetamide

Conditions

Conditions	Yield
In neat (no solvent) at 150℃; for 0.5h; Microwave irradiation;	98%
In 5,5-dimethyl-1,3-cyclohexadiene for 16h; Reflux; Inert atmosphere;	80%

: 1-acetyl-9H-β-carboline-3-carboxylic acid

: 55-81-2
4-Methoxyphenethylamine

: 1338578-37-2
marinacarboline A

Conditions

Conditions	Yield
With triethylamine; diethyl dicarbonate In N,N-dimethyl-formamide at -10 - 20℃; Inert atmosphere;	98%
With diethyl cyanophosphonate; triethylamine In N,N-dimethyl-formamide at -10 - 25℃; for 12.5h;	96%

: 103-72-0
phenyl isothiocyanate

: 55-81-2
4-Methoxyphenethylamine

: 351498-91-4
1-(2-(4-methoxyphenyl)ethyl)-3-phenylthiourea

Conditions

Conditions	Yield
In tetrahydrofuran at 20℃;	98%

: 1421782-15-1
(2R,3R,4R)-1,3,4-tris(benzyloxy)hexane-2,5-diethylsulfonate

: 55-81-2
4-Methoxyphenethylamine

: 1600532-65-7
(2S,3S,4R)-1-(4-methoxyphenethyl)-3,4-bis(benzyloxy)-2-(benzyloxymethyl)piperidine

Conditions

Conditions	Yield
at 80 - 90℃;	98%

4-Methoxyphenethylamine Chemical Properties

The Molecular formula of p-METHOXYPHENETHYLAMINE(55-81-2):C₉H₁₃NO
The Molecular Weight of p-METHOXYPHENETHYLAMINE(55-81-2):151.21
The Molecular Structure of p-METHOXYPHENETHYLAMINE(55-81-2) is:

Density:1.008 g/cm³
Melting point:249-251^°C
Boiling point:255.2 ^°C at 760 mmHg
Flash point:105.3 ^°C
Index of Refraction:1.525
Molar Refractivity:46.01 cm³
Molar Volume:149.9 cm³
Polarizability:18.24 10^-24cm³
Surface Tension:36.9 dyne/cm
Enthalpy of Vaporization:49.27 kJ/mol
Vapour Pressure:0.0165 mmHg at 25^°C
Appearance:clear colorless to slightly yellow liquid
IUPAC Name:2-(4-methoxyphenyl)ethanamine
Synonyms:4-Methoxy-2-phenethylamine;4-methoxy-benzeneethanamin;2-(4-Methoxyphenyl)ethanamine;4-Methoxybenzeneethanamine;4-Methoxy-beta-phenylethylamine;Homoanisylamine;o-methyltyramine;Phenethylamine, p-methoxy-

4-Methoxyphenethylamine Uses

Ritodrine intermediates

4-Methoxyphenethylamine Toxicity Data With Reference

ipr-mus LD50:100 mg/kg

NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) No. AD277-689 .

4-Methoxyphenethylamine Consensus Reports

Reported in EPA TSCA Inventory.

4-Methoxyphenethylamine Safety Profile

Poison by intraperitoneal route. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes:C,T
C:Corrosive
T:Toxic
Risk Statements
R34:Causes burns.
Safety Statements
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S27:Take off immediately all contaminated clothing .
RIDADR:
UN 2735 8/PG 3
WGK Germany:3
RTECS:SH7875000
F:10-23
Hazard Note:Toxic/Corrosive
HS Code:29222900

Product Name

4-Methoxyphenethylamine

Synthetic route

4-Methoxyphenethylamine Chemical Properties

4-Methoxyphenethylamine Uses

4-Methoxyphenethylamine Toxicity Data With Reference

4-Methoxyphenethylamine Consensus Reports

4-Methoxyphenethylamine Safety Profile

Related Products

Hot Products