4-Phenylbutanol supplier | CasNO.3360-41-6

Name
4-Phenylbutanol
EINECS 222-128-8
CAS No. 3360-41-6
Article Data146
CAS DataBase
Density 0.983 g/cm³
Solubility
Melting Point
Formula C₁₀H₁₄O
Boiling Point 258.8 °C at 760 mmHg
Molecular Weight 150.221
Flash Point 114.3 °C
Transport Information
Appearance colourless liquid
Safety 23-24/25-45-36/37/39-27-26
Risk Codes 34
Molecular Structure
Hazard Symbols Xi, C
Synonyms 1-Butanol,4-phenyl- (6CI,7CI,8CI);4-Phenyl-1-butanol;4-Phenyl-1-butyl alcohol;4-Phenylbutyl alcohol;NSC 71383;Phenbutanol;Phenylbutylalcohol;Benzenebutanol;
PSA 20.23000
LogP 2.00160

Synthetic route

: 7492-40-2
4-phenylbutyl acetate

A: 3360-41-6
4-phenyl-butan-1-ol

B: 108-95-2
phenol

Conditions

Conditions	Yield
With phosphate buffer; Phenyl acetate In diethyl ether for 2.75h; Ambient temperature; pig liver acetone powder;	A 5% B 100%

: 1821-12-1
4-Phenylbutyric acid

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
Stage #1: 4-Phenylbutyric acid With sodium tetrahydroborate In tetrahydrofuran at 60℃; for 0.25h; Stage #2: With iodine In tetrahydrofuran for 5h; Reagent/catalyst;	99%
Stage #1: 4-Phenylbutyric acid With sodium tetrahydroborate In tetrahydrofuran at 60℃; for 0.25h; Stage #2: With iodine In tetrahydrofuran for 5h;	98.4%
With C25H42N6Rh(1+)*CF3O3S(1-); phenylsilane In tetrahydrofuran at 30℃; for 20h; Inert atmosphere;	96%

: 2-pyridyldimethyl(4-phenylbutyl)silane

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
With potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate In tetrahydrofuran; methanol at 50℃; Oxidation;	98%
With potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate In tetrahydrofuran; methanol at 50℃; for 6h;	96%

: 72064-43-8
tert-butyldimethylsilyl 4-phenylbutyl ether

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In methanol; dichloromethane at 20 - 25℃; for 0.333333h; Flow reactor;	98%
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; for 0.5h; Inert atmosphere;	249 mg

: 7492-40-2
4-phenylbutyl acetate

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
With ytterbium(III) triflate In isopropyl alcohol for 12h; Deacetylation; Heating;	95%
With 2,2-dibutyl-1,3,2-dioxastannane; cesium fluoride In N,N-dimethyl-formamide at 20℃; for 1h;	95%

: 4830-93-7
1-Chloro-4-phenylbutane

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
With iron(III) sulfate; water In toluene at 110℃; for 1h; Ionic liquid;	95%

: 16520-62-0
4-Phenyl-1-butyne

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
With 1-hydroxytetraphenylcyclopentadienyl(tetraphenyl-2,4-cyclopentadien-1-one)-μ-hydrotetracarbonyldiruthenium(II); Ru(Cp)(PPh2PytBu)2(MeCN)PF6; water In isopropyl alcohol at 70℃; for 48h; Inert atmosphere; regioselective reaction;	95%
With [2,2]bipyridinyl; formic acid; (η5-cyclopentadienyl) (η6-naphthalene)ruthenium hexafluorophosphate; water In tetrahydrofuran at 55℃; for 48h;	88%
With formic acid; F6P(1-)*C16H22N3Ru(1+); water In 1-methyl-pyrrolidin-2-one at 25℃; for 48h; Inert atmosphere; Sealed tube;	87%

: C13H19NOS2

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
With thiophenol; 1,1'-azobis(1-cyanocyclohexanenitrile) In chlorobenzene at 110℃; for 12h;	94%

: 167693-07-4
4-phenyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butane

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
Stage #1: 4-phenyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)butane With sodium perborate tetrahydrate; water In tetrahydrofuran at 40℃; for 0.0166667h; Schlenk technique; Flow reactor; Stage #2: With sodium thiosulfate In tetrahydrofuran Schlenk technique; Flow reactor;	92%
With sodium hydroxide; dihydrogen peroxide In tetrahydrofuran at 55℃; for 3h;	80%

: 333742-34-0
2-(4-phenyl-butoxy)-tetrahydro-pyran

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
With indium(III) triflate In methanol; water at 0 - 20℃; for 6h;	92%

: 4-phenylbutyl 1-trifluoromethanesulfonate

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
With N1,N1,N12,N12-tetramethyl-7,8-dihydro-6H-dipyrido[1,2-a:2,1'-c][1,4]diazepine-2,12-diamine In N,N-dimethyl-formamide at 20℃; for 2h; Inert atmosphere;	91%

: C24H22O4

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
With palladium diacetate; sodium hydride In N,N-dimethyl acetamide at 60℃; for 4h;	91%

: (cp)Fe(CO)2(COCH2CH2Ph)

: (C5H5)Fe(CO)2((CH2)3(C6H5))

: 1631-73-8
trimethylstannane

A: 104-53-0
3-phenyl-propionaldehyde

: (C5H5)Fe(H)(CO)(Sn(CH3)3)2

C: 3360-41-6
4-phenyl-butan-1-ol

D: 18328-11-5
3-benzyl propionaldehyde

Conditions

Conditions	Yield
In benzene under Ar; 80°C, 5 h;	A <1 B 42% C 7% D 88%

...Expand

: 35656-89-4
4-(4-bromophenyl)butanoic acid

A: 3360-41-6
4-phenyl-butan-1-ol

B: 75906-36-4
4-(p-bromophenyl)-butan-1-ol

Conditions

Conditions	Yield
With lithium aluminium tetrahydride In diethyl ether at 25℃; for 2.25h;	A 10% B 88%

: 1-methoxy-4-((4-phenylbutoxy)methyl)benzene

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
With oxalyl dichloride In 1,2-dichloro-ethane at 20℃; for 2.66667h;	87%

: 101747-16-4
(4-(benzyloxy)butyl)benzene

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
With aluminium trichloride; N,N-dimethyl-aniline In dichloromethane for 0.5h; Ambient temperature;	86%
Stage #1: (4-(benzyloxy)butyl)benzene With Bromotrichloromethane; (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate In dichloromethane at 20℃; for 12h; Inert atmosphere; Irradiation; Stage #2: With methanol In dichloromethane Inert atmosphere;	67%

: 10031-93-3
ethyl 4-phenylbutyrate

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
Stage #1: ethyl 4-phenylbutyrate With polyethylsiloxane; LiTi(OPr-i)4 at 100℃; for 24h; Stage #2: With sodium hydroxide In tetrahydrofuran for 3h; Heating;	85%
With lithium aluminium tetrahydride; diethyl ether
With ethanol; sodium
With sodium hydroxide In tetrahydrofuran; water

: 273214-46-3
2-benzylsulfanyl-4-phenyl-butyraldehyde

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
With 2,2'-azobis(isobutyronitrile); n-Bu3SH In benzene for 1.5h; Reduction; Heating;	85%

: 82772-38-1
α-(trichloromethyl)benzenepropanol

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
With lithium borohydride; sodium hydroxide In isopropyl alcohol Temperature; Jocic Reaction; Heating; Inert atmosphere;	85%

: 946-02-1
4-chlorobutyl benzoate

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
Stage #1: 4-chlorobutyl benzoate With aluminum (III) chloride In benzene at -5℃; for 2h; Cooling with ice; Large scale; Stage #2: With methanol; water; sodium hydroxide Reflux; Large scale;	83%

: 109-99-9
tetrahydrofuran

: 100-59-4
phenylmagnesium chloride

A: 937-58-6, 20047-19-2, 770-36-5
(3E)-4-phenyl-3-buten-1-ol

B: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
Stage #1: tetrahydrofuran; phenylmagnesium chloride With lithium chloride; manganese(ll) chloride at 0℃; for 0.5h; Inert atmosphere; Schlenk technique; Stage #2: With iodobenzene for 1h; Inert atmosphere; Schlenk technique; Stage #3: With water Inert atmosphere; Schlenk technique;	A 7% B 81%

...Expand

: 4-phenylbutan-1-yl diphenylmethylsilyl ether

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
With potassium (4-methylphenyl)trifluoroborate In dimethyl sulfoxide at 37℃; for 10h; Inert atmosphere;	80%

: 104-53-0
3-phenyl-propionaldehyde

: pyrocatecholborane

: 18107-18-1
diazomethyl-trimethyl-silane

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
Stage #1: 3-phenyl-propionaldehyde; diazomethyl-trimethyl-silane With triphenylphosphine; isopropyl alcohol; Wilkinson's catalyst In tetrahydrofuran at 20℃; for 2h; Stage #2: pyrocatecholborane In 1,4-dioxane at 20℃; for 2h; Stage #3: With sodium hydroxide; dihydrogen peroxide In 1,4-dioxane at 20℃; for 3h;	79%

...Expand

: 1126-76-7
1,2-Epoxy-4-phenylbutane

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
With bis(cyclopentadienyl)titanium dichloride; manganese; water In tetrahydrofuran at 20℃; for 24h; Inert atmosphere;	79%
With bis(cyclopentadienyl)titanium dichloride; manganese; water In tetrahydrofuran for 6h;	78%

: 135886-84-9
(4-(tert-butoxy)butyl)benzene

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
With zinc dibromide In dichloromethane for 24h; dealkylation;	78%

: 2,3-(dibenzylthio)-4-phenylbutanal

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
With 2,2'-azobis(isobutyronitrile); n-Bu3SH In benzene Reduction;	77%

: 13214-66-9
4-phenyl-1-butylamine

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
With potassium hydroxide In diethylene glycol at 210℃; for 12h; Product distribution; Further Variations:; Reaction partners; Solvents;	76%
With potassium hydroxide In diethylene glycol at 210℃; Substitution;	59%

: 4850-50-4
1-phenyl-butane-1,4-diol

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
With indium(III) chloride; diphenylsilyl chloride In 1,2-dichloro-ethane at 80℃; for 3h;	76%

: 201230-82-2
carbon monoxide

: 4119-41-9
1-iodo-3-phenylpropan

: 3360-41-6
4-phenyl-butan-1-ol

Conditions

Conditions	Yield
Stage #1: carbon monoxide; 1-iodo-3-phenylpropan With diethoxymethylane; [CuCl(IPrMe)]; lithium methanolate In tetrahydrofuran at 60℃; under 2280.15 Torr; for 16h; Sealed tube; Stage #2: With tetrabutyl ammonium fluoride In tetrahydrofuran; diethyl ether at 20℃; for 2h; Catalytic behavior; Reagent/catalyst; Pressure;	75%

: 3360-41-6
4-phenyl-butan-1-ol

: 4830-93-7
1-Chloro-4-phenylbutane

Conditions

Conditions	Yield
With tetra-(n-butyl)ammonium iodide; 1,2-dichloro-ethane; triphenylphosphine at 120℃; for 0.5h; Sealed tube; Inert atmosphere;	100%
With oxalyl dichloride In dichloromethane at 20℃; Appel Halogenation; Reflux;	98%
With thionyl chloride at 20℃; for 1.5h; Cooling with ice; Large scale;	94%

: 3360-41-6
4-phenyl-butan-1-ol

: 18328-11-5
3-benzyl propionaldehyde

Conditions

Conditions	Yield
With sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine In dichloromethane at 0℃; for 1h; Inert atmosphere;	100%
With pyridinium chlorochromate In dichloromethane at 20℃; for 3h;	100%
With oxalyl dichloride; dimethyl sulfoxide In dichloromethane at -55℃; for 0.25h; Oxidation; Swern oxidation;	99%

: 3360-41-6
4-phenyl-butan-1-ol

: 62-23-7
4-nitro-benzoic acid

: 4-phenylbutyl 4-nitrobenzoate

Conditions

Conditions	Yield
With [bis(acetoxy)iodo]benzene; triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 25℃; for 16h; Mitsunobu reaction;	100%

: 3360-41-6
4-phenyl-butan-1-ol

: 4-(1,4-cyclohexadien-1-yl)-1-butanol

Conditions

Conditions	Yield
With ammonia; sodium In ethanol at -78 - 20℃; Birch reduction;	100%
With lithium In ethanol; ammonia at -78 - 20℃; Birch Reduction; liquid NH3;	98.3%

: 558-13-4
carbon tetrabromide

: 3360-41-6
4-phenyl-butan-1-ol

: 13633-25-5
1-Bromo-4-phenylbutane

Conditions

Conditions	Yield
With triphenylphosphine In dichloromethane; hexane-diethyl ether	100%

: 3360-41-6
4-phenyl-butan-1-ol

: 7332-01-6
1-(4-azidobutyl)benzene

Conditions

Conditions	Yield
Stage #1: 4-phenyl-butan-1-ol With 1,2-Diiodoethane; N,N-dimethyl-formamide; triphenylphosphine at 20℃; for 0.0166667h; Sealed tube; Inert atmosphere; Stage #2: With sodium azide at 20℃; Sealed tube; Inert atmosphere;	100%
Stage #1: 4-phenyl-butan-1-ol With dmap; triethylamine; p-toluenesulfonyl chloride In dichloromethane at 0 - 20℃; Stage #2: With sodium azide In N,N-dimethyl-formamide at 20℃;	55%
With sodium azide; methanesulfonyl chloride
Multi-step reaction with 2 steps 1: triphenylphosphine; iodine; 1H-imidazole / 5.25 h / 0 - 20 °C 2: sodium azide / N,N-dimethyl-formamide / 18 h / 20 °C View Scheme

: 3360-41-6
4-phenyl-butan-1-ol

: 825-83-2
4-trifluoromethylbenzenethiol

: (4-phenylbutyl)(4-(trifluoromethyl)phenyl)sulfane

Conditions

Conditions	Yield
Stage #1: 4-phenyl-butan-1-ol With 1,2-Diiodoethane; N,N-dimethyl-formamide; triphenylphosphine at 20℃; for 0.0166667h; Sealed tube; Inert atmosphere; Stage #2: 4-trifluoromethylbenzenethiol at 20℃; Sealed tube; Inert atmosphere;	100%

: 3360-41-6
4-phenyl-butan-1-ol

: 139-02-6
sodium phenoxide

: 358349-92-5
(4-phenoxybutyl)benzene

Conditions

Conditions	Yield
Stage #1: 4-phenyl-butan-1-ol With 1,2-Diiodoethane; N,N-dimethyl-formamide; triphenylphosphine at 20℃; for 0.0166667h; Sealed tube; Inert atmosphere; Stage #2: sodium phenoxide at 20℃; Sealed tube; Inert atmosphere;	100%

: 3360-41-6
4-phenyl-butan-1-ol

: 1122-95-8
sodium 4-methoxyphenolate

: 1-methoxy-4-(4-phenylbutoxy)benzene

Conditions

Conditions	Yield
Stage #1: 4-phenyl-butan-1-ol With 1,2-Diiodoethane; N,N-dimethyl-formamide; triphenylphosphine at 20℃; for 0.0166667h; Sealed tube; Inert atmosphere; Stage #2: sodium 4-methoxyphenolate at 20℃; Sealed tube; Inert atmosphere;	100%

: 3360-41-6
4-phenyl-butan-1-ol

: 127-08-2
potassium acetate

: 7492-40-2
4-phenylbutyl acetate

Conditions

Conditions	Yield
Stage #1: 4-phenyl-butan-1-ol With 1,2-Diiodoethane; N,N-dimethyl-formamide; triphenylphosphine at 20℃; for 0.0166667h; Sealed tube; Inert atmosphere; Stage #2: potassium acetate at 20℃; Sealed tube; Inert atmosphere;	100%

: 3360-41-6
4-phenyl-butan-1-ol

: 857839-66-8
4-phenylbutyl benzoate

Conditions

Conditions	Yield
With potassium hydroxide; benzoic acid	99.7%

: 3360-41-6
4-phenyl-butan-1-ol

: 13633-25-5
1-Bromo-4-phenylbutane

Conditions

Conditions	Yield
With hydrogen bromide for 12h; Reagent/catalyst; Irradiation; Reflux;	99.6%
With allyl bromide; 1,1'-carbonyldiimidazole In acetonitrile for 1h; Heating;	98%
With carbon tetrabromide; triphenylphosphine In dichloromethane at 25℃;	95%

: 3360-41-6
4-phenyl-butan-1-ol

: 124-63-0
methanesulfonyl chloride

: 65512-08-5
4-phenylbutyl methanesulfonate

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0 - 20℃; for 3h; Inert atmosphere;	99%
With triethylamine In dichloromethane for 16h; Ambient temperature;	96%
With triethylamine In dichloromethane at 5 - 10℃; for 1h;	91%

: 3360-41-6
4-phenyl-butan-1-ol

: 64-19-7
acetic acid

: 7492-40-2
4-phenylbutyl acetate

Conditions

Conditions	Yield
With iron(III) chloride at 20℃; for 1h; Esterification;	99%
With tetrabutylammomium bromide; oxygen; sodium nitrite at 70℃; for 4h; Green chemistry;	81%

: 3360-41-6
4-phenyl-butan-1-ol

: 507-09-5
thioacetic acid

: 294201-60-8
S-(4-phenylbutyl) ethanethioate

Conditions

Conditions	Yield
With di-isopropyl azodicarboxylate; triphenylphosphine In tetrahydrofuran at 0 - 20℃; for 1.5h; thioacetylation;	99%

: 3360-41-6
4-phenyl-butan-1-ol

: C10H6(2)H8O

Conditions

Conditions	Yield
With hydrogen; water-d2; palladium on activated charcoal at 110℃; under 760.051 Torr; for 24h;	99%

: 623-03-0
4-Cyanochlorobenzene

: 3360-41-6
4-phenyl-butan-1-ol

: 138631-41-1
4-(4-phenylbutoxy)benzonitrile

Conditions

Conditions	Yield
Stage #1: 4-phenyl-butan-1-ol With sodium methylate In methanol at 130℃; for 2h; Stage #2: 4-Cyanochlorobenzene In methanol at 100℃; for 15h; Reagent/catalyst; Temperature; Solvent;	98.1%

: 136918-14-4
phthalimide

: 3360-41-6
4-phenyl-butan-1-ol

: 54981-87-2
2-(4-phenylbutyl)-1H-isoindole-1,3(2H)-dione

Conditions

Conditions	Yield
With triphenylphosphine; 3,3-dimethyl-1,2,5-thiadiazolidine-1,1-dioxide In dichloromethane for 2.5h; Ambient temperature;	98%

: 124-38-9
carbon dioxide

: 3360-41-6
4-phenyl-butan-1-ol

: 78-76-2, 5787-31-5
s-butyl bromide

: carbonic acid sec-butyl ester 4-phenyl-butyl ester

Conditions

Conditions	Yield
Stage #1: carbon dioxide; 4-phenyl-butan-1-ol With tetra-(n-butyl)ammonium iodide; caesium carbonate In N,N-dimethyl-formamide at 23℃; for 1h; Stage #2: s-butyl bromide In N,N-dimethyl-formamide at 23℃; for 23h;	98%
With tetra-(n-butyl)ammonium iodide; caesium carbonate In N,N-dimethyl-formamide at 23℃; for 4h;	91%

...Expand

: 3360-41-6
4-phenyl-butan-1-ol

: 2524-64-3
chlorophosphoric acid diphenyl ester

: diphenyl (4-phenylbutyl) phosphate

Conditions

Conditions	Yield
With pyridine N-oxide; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene In dichloromethane at 20℃; for 2h; Reagent/catalyst; Inert atmosphere;	98%

: 3360-41-6
4-phenyl-butan-1-ol

: 13338-63-1
2-(3,4,5-trimethoxyphenyl)acetonitrile

: C21H25NO3

Conditions

Conditions	Yield
With [carbonylchlorohydrido{bis[2-(diphenylphosphinomethyl)ethyl]amino}ethylamino] ruthenium(II); potassium tert-butylate In toluene at 135℃; for 4h; Inert atmosphere;	98%

: 3360-41-6
4-phenyl-butan-1-ol

: 637-59-2
1-Bromo-3-phenylpropane

: C19H24O

Conditions

Conditions	Yield
With cesium hydroxide; 4 A molecular sieve; tetra-(n-butyl)ammonium iodide In N,N-dimethyl-formamide at 23℃; for 11h;	97%

: 3360-41-6
4-phenyl-butan-1-ol

: 100-39-0
benzyl bromide

: 101747-16-4
(4-(benzyloxy)butyl)benzene

Conditions

Conditions	Yield
With cesium hydroxide; 4 A molecular sieve In N,N-dimethyl-formamide at 23℃; for 3h;	97%
Stage #1: 4-phenyl-butan-1-ol With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 0.5h; Inert atmosphere; Stage #2: benzyl bromide In tetrahydrofuran; mineral oil at 20℃; for 12h; Inert atmosphere;

: 3360-41-6
4-phenyl-butan-1-ol

: 534-17-8
caesium carbonate

: 100-44-7
benzyl chloride

: carbonic acid benzyl ester 4-phenyl-butyl ester

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 95℃; for 36h;	97%

...Expand

: 197507-22-5
methyl 2-fluoro-4-hydroxybenzoate

: 3360-41-6
4-phenyl-butan-1-ol

: methyl 4-(4-phenylbutoxy)-2-fluorobenzoate

Conditions

Conditions	Yield
	97%

: 130830-27-2
[(p-cymene)Ru(OTf)2]

: 3360-41-6
4-phenyl-butan-1-ol

: [(p-cymene)Ru(4-phenyl-1-butanol)][OTf]2

Conditions

Conditions	Yield
In nitromethane (Ar); addn. of ligand to a mixt. of ruthenium complex and CH3NO2, heating to 60°C for 30 min; layering with CH2Cl2 and Et2O, standing overnight at -20°C, sepn., washing with CH2Cl2 and Et2O, drying in vac.; elem. anal.;	97%

4-Phenylbutanol Chemical Properties

IUPAC Name: 4-Phenylbutan-1-ol
Synonyms of Benzenebutanol (CAS NO.3360-41-6): 4-Phenylbutanol ; AI3-11560 ; EINECS 222-128-8 ; NSC 71383 ; Phenylbutyl alcohol ; 1-Butanol, 4-phenyl- (8CI) ; 4-Phenylbutan-1-ol
CAS NO: 3360-41-6
Molecular Formula: C₁₀H₁₄O
Molecular Weight: 150.2176
Molecular Structure:

Product Categories: Starting Raw Materials & Intermediates ; Alcohols ; C9 to C30 ; Oxygen Compounds
H bond acceptors: 1
H bond donors: 1
Freely Rotating Bonds: 5
Polar Surface Area: 9.23 Å²
Index of Refraction: 1.522
Molar Refractivity: 46.6 cm³
Molar Volume: 152.7 cm³
Surface Tension: 38.3 dyne/cm
Density of Benzenebutanol (CAS NO.3360-41-6): 0.983 g/cm³
Flash Point: 114.3 °C
Enthalpy of Vaporization: 52.45 kJ/mol
Boiling Point: 258.8 °C at 760 mmHg
Vapour Pressure: 0.00686 mmHg at 25°C

4-Phenylbutanol Safety Profile

Hazard Codes of Benzenebutanol (CAS NO.3360-41-6): Irritant Xi, Corrosive C
Risk Statements: 34
R34: Causes burns.
Safety Statements: 23-24/25-45-36/37/39-27-26
S23: Do not breathe vapour.
S24/25: Avoid contact with skin and eyes.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S27: Take off immediately all contaminated clothing.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 3
RTECS: 222-128-8
HS Code: 29062900

Product Name

4-Phenylbutanol

Synthetic route

4-Phenylbutanol Chemical Properties

4-Phenylbutanol Safety Profile

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