Amoxicillin supplier | CasNO.26787-78-0

Name
Amoxicillin
EINECS 248-003-8
CAS No. 26787-78-0
Article Data30
CAS DataBase
Density 1.54 g/cm³
Solubility 4g/L at 25℃
Melting Point 140 °C
Formula C₁₆H₁₉N₃O₅S
Boiling Point 743.2 °C at 760 mmHg
Molecular Weight 365.41
Flash Point 403.3 °C
Transport Information
Appearance solid
Safety 22-36/37
Risk Codes 42/43
Molecular Structure
Hazard Symbols Xn, Xi
Synonyms 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[2-amino-2-(p-hydroxyphenyl)acetamido]-3,3-dimethyl-7-oxo-, D- (8CI);Eupensol;Excillin;Farconcil;Fisamox;Foxolin;Fullcilina;Gemox;Gimalxina;Gomcillin;Gramidil;Grunamox;Hiconcil;Hipen;Histocillin;Hosboral;Imacillin;Imaxilin;Imox;Imoxil;Intermox;Jerramcil;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-, [2S-[2a,5a,6b(S*)]]-;6-[D-(-)-p-Hydroxy-a-aminobenzyl]penicillin;6-[D-a-Amino-a-(4-hydroxyphenyl)acetamido]penicillanicacid;A-Gram;Actimoxi;Agerpen;Alfamox;Almodan;Alphamox;Amagesen Solutab;Amodex;Amoflux;Amopenixin;Amoxa;Amoxal;Amoxapen;Amoxaren;Amoxi;Amoxi-Mast;Amoxicilina;Amoxidal;Amoxiden;Amoxil;Amoxin;Amoxipen;Amoxtrex;Amoxy;Amoxypen;Ampidroxyl;Ampy-Penyl;Anemol;Anemolin;Apitart;Apo-Amoxi;Ardine;Aspenil;Audumic;BLP1410;BRL 2333;Bactox;Betamox;Bimox;Biomox;Bioxidona;Bioxyllin;Cabermox;Cilamox;Clamox;Clamoxyl;Coamoxin;Comoxyl;D-(-)-a-Amino-p-hydroxybenzyl penicillin;D-2-Amino-2-(4-hydroxyphenyl)acetamidopenicillanic acid;D-Amoxicillin;Delacillin;Efpenix;Efpinex;Eupen;
PSA 158.26000
LogP 1.05280

Synthetic route

: C31H29N3O7S

: 26787-78-0
amoxicillin

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen In methanol; water for 3h;	62%

: 551-16-6
6-Aminopenicillanic Acid

: 37763-23-8
D-2-p-hydroxyphenylglycine methyl ester

: 26787-78-0
amoxicillin

Conditions

Conditions	Yield
at 30℃; for 3h; Pseudomonas melanogenum KY 3987 and KY 8540; Yield given;
With penicillin acylasefrom Escherichia coli; water

: 551-16-6
6-Aminopenicillanic Acid

: 57591-61-4, 68697-60-9, 127369-30-6, 134694-94-3
methyl (R)-2-amino-2-(4-hydroxyphenyl)acetate hydrochloride

: 26787-78-0
amoxicillin

Conditions

Conditions	Yield
With iso-butanol In water at 20℃; Xanthomonas citri K24, pH = 6-7; Yield given;

: 75-21-8
oxirane

: cefprozil

: 26787-78-0
amoxicillin

Conditions

Conditions	Yield
In sodium amoxycillin; water; amoxycillin trihydrate; cefaclor monohydrate

: ethoxy carbonyl D-α-(1-carbomethoxy-propenyl)amino p-hydroxy phenyl acetate

: 7732-18-5
water

: 26787-78-0
amoxicillin

Conditions

Conditions	Yield
With hydrogenchloride; sodium hydroxide In acetone

: 32462-30-9
(S)-hydroxyphenylglycine

: 3282-30-2
pivaloyl chloride

: 141-97-9
ethyl acetoacetate

: 551-16-6, 1079-37-4, 3115-55-7, 21794-93-4, 145920-51-0
6-aminopenicillanic acid

: 26787-78-0
amoxicillin

Conditions

Conditions	Yield
With triethylamine In ethanol; dichloromethane

...Expand

triethylamine (TEA): triethylamine (TEA)

: 82095-48-5, 95510-67-1
D(-)-p-hydroxy-N-(1-ethoxycarbonyl-2-propenyl)-alpha-aminophenylacetic acid potassium salt

3-trimethylsilyl-2-oxazolidinone (TMSO): 3-trimethylsilyl-2-oxazolidinone (TMSO)

: 3282-30-2
pivaloyl chloride

: 551-16-6, 1079-37-4, 3115-55-7, 21794-93-4, 145920-51-0
6-aminopenicillanic acid

: 26787-78-0
amoxicillin

Conditions

Conditions	Yield
In dichloromethane; ISOPROPYLAMIDE; water

...Expand

: 551-16-6, 1079-37-4, 3115-55-7, 21794-93-4, 145920-51-0
6-aminopenicillanic acid

: 26787-78-0
amoxicillin

: 551-16-6, 1079-37-4, 3115-55-7, 21794-93-4, 145920-51-0
6-aminopenicillanic acid

A: 26787-78-0
amoxicillin

B: 760-67-8
2-ethylhexanoic acid chloride

: Methoxycarbonyl D-α-(1-carbomethoxypropen-2-yl)amino-p-hydroxyphenyl-acetate

: 551-16-6, 1079-37-4, 3115-55-7, 21794-93-4, 145920-51-0
6-aminopenicillanic acid

: 10416-58-7
N,N-bis(trimethylsilyl)acetamide

: 26787-78-0
amoxicillin

...Expand

: 82095-48-5, 95510-67-1
D(-)-p-hydroxy-N-(1-ethoxycarbonyl-2-propenyl)-alpha-aminophenylacetic acid potassium salt

: 68698-88-4
N-triisopropylsilyl-2-oxazolidinone

: 26787-78-0
amoxicillin

Conditions

Conditions	Yield
With triethylamine hydrochloride In N-methyl-acetamide; dichloromethane

: 551-16-6, 1079-37-4, 3115-55-7, 21794-93-4, 145920-51-0
6-aminopenicillanic acid

: 822-39-9
2-chloro-1,3,2-dioxaphospholan

: 26787-78-0
amoxicillin

Conditions

Conditions	Yield
With chloro-trimethyl-silane; diisopropylamine In dichloromethane

: potassium D-α-(1-carbomethoxypropen-2-yl)-amino-p-hydroxyphenylacetate

: 79-22-1
methyl chloroformate

: 26787-78-0
amoxicillin

Conditions

Conditions	Yield
With chloro-trimethyl-silane; triethylamine In dichloromethane; N,N-dimethyl-formamide

: 73590-58-6
omeprazole

: 26787-78-0
amoxicillin

: 69-65-8
mannitol

A: 26787-78-0
amoxicillin

B: clarithromycin

: 51481-61-9, 76181-71-0, 270574-63-5, 785731-92-2, 752934-25-1
cimetidine

: 26787-78-0
amoxicillin

: 732216-08-9
famotidine

: 26787-78-0
amoxicillin

: 551-16-6
6-Aminopenicillanic Acid

: D-(-)-4-hydroxyphenylglycineamide

: 26787-78-0
amoxicillin

Conditions

Conditions	Yield
With penicillin acylasefrom Escherichia coli; water

: 551-16-6
6-Aminopenicillanic Acid

: 43189-12-4
(R)-methyl 2-amino-2-(4-hydroxyphenyl)acetate

: 26787-78-0
amoxicillin

Conditions

Conditions	Yield
With penicillin G acylase at 20℃; Enzymatic reaction;

: C24H25N3O7S

: 26787-78-0
amoxicillin

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen In methanol; water for 3h;

: 22818-40-2
D-4-hydroxyphenylglycine

: 26787-78-0
amoxicillin

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: sodium hydrogencarbonate / tetrahydrofuran; water / 8.42 h 2.1: chloroformic acid ethyl ester; N-ethyl-N,N-diisopropylamine / 1-methyl-pyrrolidin-2-one / 0.33 h / 0 °C 2.2: -60 - 20 °C 3.1: palladium 10% on activated carbon; hydrogen / water; methanol / 3 h View Scheme

: 34642-77-8
Acuotricina

A: diketopiperazine

B: 26787-78-0
amoxicillin

Conditions

Conditions	Yield
With 1,4-dithio-L-threitol In water at 20℃; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;

: 26787-78-0
amoxicillin

: 109-76-2
Trimethylenediamine

: C19H29N5O5S

Conditions

Conditions	Yield
With sodium carbonate In water at 0 - 20℃; for 3h; pH=4; Inert atmosphere;	100%

: 646-19-5
heptane-1,7-diamine

: 26787-78-0
amoxicillin

: C23H37N5O5S

Conditions

Conditions	Yield
With sodium carbonate In water at 0 - 20℃; for 3h; pH=4; Inert atmosphere;	100%

: 24424-99-5
di-tert-butyl dicarbonate

: 26787-78-0
amoxicillin

: C21H27N3O7S

Conditions

Conditions	Yield
With sodium hydrogencarbonate In 1,4-dioxane; water at 0 - 20℃;	97%
With potassium carbonate In 1,4-dioxane; water at 0 - 25℃; for 1.5h;

: 26787-78-0
amoxicillin

: C16H21N4O5S(1-)*Na(1+)

Conditions

Conditions	Yield
Stage #1: amoxicillin With ammonium hydroxide for 0.333333h; Stage #2: With sodium hydroxide at 20℃; for 4h;	96%

: 123-41-1
cholin hydroxide

: 26787-78-0
amoxicillin

: C16H21N4O5S(1-)*C5H14NO(1+)

Conditions

Conditions	Yield
Stage #1: amoxicillin With ammonium hydroxide In methanol Stage #2: cholin hydroxide In methanol at 20℃; for 1h;	93%

: 951163-09-0
trihexyl(tetradecyl) phosphonium hydroxide

: 26787-78-0
amoxicillin

: C16H21N4O5S(1-)*C32H68P(1+)

Conditions

Conditions	Yield
Stage #1: amoxicillin With ammonium hydroxide In methanol Stage #2: trihexyl(tetradecyl) phosphonium hydroxide In methanol at 20℃; for 1h;	92%

: 26787-78-0
amoxicillin

: 34642-77-8
Acuotricina

Conditions

Conditions	Yield
Stage #1: amoxicillin With triethylamine In methanol; acetic acid methyl ester at 0 - 5℃; Stage #2: With sodium 2-ethylhexanoic acid In methanol; acetic acid methyl ester at 0 - 5℃; Product distribution / selectivity;	90%
With sodium hydroxide In water Product distribution / selectivity;
With sodium hydrogencarbonate In water Product distribution / selectivity;
With sodium carbonate In water Product distribution / selectivity;

: C5H9N2O3(1-)*K(1+)

: 26787-78-0
amoxicillin

: 6-[D-2-(D-2-amino-3-N-methylcarbamoylpropionamido)-2-p-hydroxyphenylacetamido]penicillanic acid

Conditions

Conditions	Yield
Stage #1: amoxicillin With trimethylsilyl iodide; triethylamine In dichloromethane at 0℃; for 3h; Stage #2: C5H9N2O3(1-)*K(1+) With 4-methyl-morpholine; chloroformic acid ethyl ester In dichloromethane at -10 - -5℃; for 15h;	90%

: 26787-78-0
amoxicillin

: 105-45-3
acetoacetic acid methyl ester

: (Z)-6-(2-(4-hydroxyphenyl)-2-([4-methoxy-4-oxobut-2-en-2-yl]amino)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 0 - 20℃; for 6h;	86.98%

: (R)-1-benzothiazol-2-(4-ethoxy-4-peroxybutanol-2-enyl-2-yl)amino-4-(methylamino)-4-oxothiobutyrate

: 26787-78-0
amoxicillin

: 6-[D-2-(D-2-amino-3-N-methylcarbamoylpropionamido)-2-p-hydroxyphenylacetamido]penicillanic acid

Conditions

Conditions	Yield
In ethanol; water at -10 - -5℃; for 2.5h; pH=7.5;	85.2%

: 26787-78-0
amoxicillin

: [(2,3-bis-methoxycarbonyloxy-benzoyl)-(8-{(2,3-bis-methoxycarbonyloxy-benzoyl)-[8-(8-methoxycarbonyloxy-2,4-dioxo-4H-benzo[e][1,3]oxazin-3-yl)-octyl]-amino}-octyl)-amino]-acetic acid

: C66H76N6O26S

Conditions

Conditions	Yield
Stage #1: [(2,3-bis-methoxycarbonyloxy-benzoyl)-(8-{(2,3-bis-methoxycarbonyloxy-benzoyl)-[8-(8-methoxycarbonyloxy-2,4-dioxo-4H-benzo[e][1,3]oxazin-3-yl)-octyl]-amino}-octyl)-amino]-acetic acid With 4-methyl-morpholine; methyl chloroformate In tetrahydrofuran at -10℃; for 1h; Stage #2: amoxicillin With triethylamine In tetrahydrofuran	83%

: 26787-78-0
amoxicillin

: 90-02-8
salicylaldehyde

: C23H23N3O6S

Conditions

Conditions	Yield
With sodium hydroxide In methanol; water for 2h; pH=7 - 8; Reflux;	81%
In ethanol for 3h; Inert atmosphere;	70%

: 646-19-5
heptane-1,7-diamine

: 26787-78-0
amoxicillin

: C23H35N5O4S

Conditions

Conditions	Yield
With 1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 0 - 20℃; for 3h; Inert atmosphere;	81%

: 26787-78-0
amoxicillin

: 477947-79-8
C11H16ClNO4Si

: (2R,5R)-3-[2-{[(R)-((2S,5R,6R)-2-Carboxy-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-6-ylcarbamoyl)-(4-hydroxy-phenyl)-methyl]-amino}-eth-(Z)-ylidene]-7-oxo-4-oxa-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid

Conditions

Conditions	Yield
Stage #1: amoxicillin With chloro-trimethyl-silane; triethylamine In acetonitrile at 25℃; for 1h; Stage #2: C11H16ClNO4Si In acetonitrile at 25℃; for 6h;	80%

: (8-methoxycarbonyloxy-2,4-dioxobenzoxazin-3-yl)-acetyl chloride

: 26787-78-0
amoxicillin

: N-[(8-methoxycarbonyloxy-2,4-dioxobenzoxazin-3-yl)-acetyl]-amoxicillin

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran; water; ethyl acetate; Petroleum ether	80%

: 462-94-2
1,5-diaminopentane

: 26787-78-0
amoxicillin

: C21H33N5O5S

Conditions

Conditions	Yield
With sodium carbonate In water at 0 - 20℃; for 3h; pH=4; Inert atmosphere;	80%

: 26787-78-0
amoxicillin

: 77997-18-3
1-hydro-5-(p-aminosulfonyl)anilino-2-hydroxy-oxazolo<5,4-d>pyrimidine

: 6R-<(R)-2-<3-<2-(p-Aminosulfonyl)anilino-4-hydroxy-5-pyrimidinyl>ureido>-2-(4-hydroxyphenyl)-acetamido>-penicillansaeure, Natriumsalz

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran; water for 1h;	78%

: 26787-78-0
amoxicillin

: 501-53-1
benzyl chloroformate

: (2S,5R,6R)-3,3-dimethyl-6-[(R)-2-(benzyloxycarbonylamino)-2-(4-benzyloxycarbonyloxyphenyl)acetamido]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Conditions

Conditions	Yield
Stage #1: amoxicillin With sodium hydroxide In tetrahydrofuran; water at 20℃; for 0.166667h; Stage #2: benzyl chloroformate In tetrahydrofuran; water Time; Cooling with ice;	77%

: 26787-78-0
amoxicillin

: 1-ethyl-3-methylimidazolium hydroxide

: C16H21N4O5S(1-)*C6H11N2(1+)

Conditions

Conditions	Yield
Stage #1: amoxicillin With ammonium hydroxide Stage #2: 1-ethyl-3-methylimidazolium hydroxide In methanol at 20℃; for 1h;	77%

: 65-22-5
pyridoxal hydrochloride

: 26787-78-0
amoxicillin

: C24H26N4O7S

Conditions

Conditions	Yield
With potassium hydroxide In methanol for 0.0416667h; pH=7 - 8; Microwave irradiation;	73%

: 26787-78-0
amoxicillin

: 137-07-5
2-amino-benzenethiol

: C22H22N4O3S2

Conditions

Conditions	Yield
With hydrogenchloride In water for 3h; Reflux;	70%

: 26787-78-0
amoxicillin

: N-carboxyanhydride of D-4-hydroxyphenylglycine

: 4-hydroxyphenylglycylamoxicillin

Conditions

Conditions	Yield
With sodium hydroxide; phosphate buffer In 1,4-dioxane at 0℃; for 1h;	69%

: 26787-78-0
amoxicillin

: 473988-39-5
3-methyl-4-oxo-imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxylic acid N-hydroxysuccinimide ester

: α-[(3-methyl-4-oxo-imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxyl)amino-p-hydroxybenzyl]penicillin

Conditions

Conditions	Yield
With triethylamine In N,N-dimethyl-formamide at 20 - 30℃; for 4h;	69%

: 26787-78-0
amoxicillin

: 95-54-5
1,2-diamino-benzene

: C22H23N5O3S

Conditions

Conditions	Yield
With hydrogenchloride In water for 3h; Reflux;	68%

: 141-86-6
2,6-Diaminopyridine

: 26787-78-0
amoxicillin

: C21H24N6O4S

Conditions

Conditions	Yield
In ethanol for 3h; Reflux; Inert atmosphere;	67%

: C14H13NO5

: 26787-78-0
amoxicillin

: C27H26N4O7S

Conditions

Conditions	Yield
With triethylamine In water; acetone at -12 - 20℃; for 3.75h;	66%

: 26787-78-0
amoxicillin

: 473988-44-2
3-(2-chloroethyl)-4-oxo-imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxylic acid N-hydroxysuccinimide ester

: α-[(3-(2-chloroethyl)-4-oxo-imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxyl)amino-p-hydroxybenzyl]penicillin

Conditions

Conditions	Yield
With triethylamine In N,N-dimethyl-formamide at 20 - 30℃; for 4h;	65%

: 26787-78-0
amoxicillin

: 90-99-3
diphenylchloromethane

: 477947-68-5
diphenylmethyl 6β-[(R)-2-(diphenylmethylamino)-2-(4-hydroxyphenyl)acetamido]penicillanate

Conditions

Conditions	Yield
With triethylamine In acetonitrile at 25℃; for 3h;	65%

: C15H15NO6

: 26787-78-0
amoxicillin

: C28H28N4O8S

Conditions

Conditions	Yield
With triethylamine In water; acetone at -12 - 20℃; for 3.75h;	64%

Amoxicillin Chemical Properties

Structure of Amoxicillin (CAS NO.26787-78-0):

IUPAC Name: (2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Empirical Formula: C₁₆H₁₉N₃O₅S
Molecular Weight: 365.4042
EINECS: 248-003-8
Index of Refraction: 1.701
Molar Refractivity: 91.47 cm³
Molar Volume: 236.2 cm³
Polarizability: 36.26×10^-24cm³
Surface Tension: 85.3 dyne/cm
Density: 1.54 g/cm³
Flash Point: 403.3 °C
Enthalpy of Vaporization: 113.73 kJ/mol
Boiling Point: 743.2 °C at 760 mmHg
Vapour Pressure: 3.39E-23 mmHg at 25°C
Stability: Stable. Incompatible with strong oxidizing agents.
Product Categories: Antibiotics;A - KAntibiotics;Antibacterial;Antibiotics A to;Antibiotics A-FAntibiotics;Chemical Structure Class;Interferes with Cell Wall SynthesisAntibiotics;Mechanism of Action;Penicillins and Cephalosporins (beta-Lactams);Spectrum of Activity

Amoxicillin Uses

Amoxicillin can be used as broad-spectrum semi-synthetic PENICILLIN. It is active against gram-positive and -negative bacteri. Clinic for the treatment of tonsillitis, laryngitis, pneumonia, chronic bronchitis, urinary tract infections, skin and soft tissue infections, septic pleurisy, hepatobiliary system infections, sepsis, typhoid, dysentery. The antimicrobial spectrum of goods for drugs, and its role and application of both PENICILLIN and Benzyl chloride similar strengths of the serum protein binding rate and blood concentration more than twice as high as ampicillin.

Amoxicillin Production

6-APA and N-(3-ethoxycarbonyl-1-methyl vinyl) Sodium p-hydroxyphenylglycine derived by condensation. 6- APA is the production of a wide range of semi-synthetic PENICILLIN important raw materials. Large industrial use of microorganisms PENICILLIN lactamase cracker natural PENICILLIN (PENICILLIN G or PENICILLIN V) approach to the admission system.

Amoxicillin Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
child	TDLo	oral	300mg/kg (300mg/kg)	KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" KIDNEY, URETER, AND BLADDER: HEMATURIA KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION	Clinical Pediatrics Vol. 32, Pg. 735, 1993.
child	TDLo	oral	682mg/kg (682mg/kg)	KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED KIDNEY, URETER, AND BLADDER: HEMATURIA	Clinical Pediatrics Vol. 32, Pg. 735, 1993.
man	TDLo	oral	7143ug/kg (7.143mg/kg)	SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Allergy. Vol. 52(Suppl,
man	TDLo	oral	40mg/kg/4D (40mg/kg)	GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: OTHER CHANGES	Lancet. Vol. 2, Pg. 707, 1978.
mouse	LD50	intracrebral	> 500mg/kg (500mg/kg)	BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS	Chemotherapy Vol. 26, Pg. 196, 1980.
mouse	LD50	intraperitoneal	3590mg/kg (3590mg/kg)		Drugs in Japan Vol. -, Pg. 59, 1990.
mouse	LD50	oral	> 25gm/kg (25000mg/kg)		Drugs in Japan Vol. 6, Pg. 38, 1982.
mouse	LD50	subcutaneous	> 20mg/kg (20mg/kg)		Drugs in Japan Vol. -, Pg. 59, 1990.
rat	LD50	intraperitoneal	2870mg/kg (2870mg/kg)		Drugs in Japan Vol. -, Pg. 59, 1990.
rat	LD50	oral	> 15gm/kg (15000mg/kg)		Drugs in Japan Vol. 6, Pg. 38, 1982.
rat	LD50	subcutaneous	> 8gm/kg (8000mg/kg)		Drugs in Japan Vol. -, Pg. 59, 1990.

Amoxicillin Safety Profile

Hazard Codes : Harmful Xn, Irritant Xi
Risk Statements : 42/43
R42/43:May cause sensitization by inhalation and skin contact.
Safety Statements : 22-36/37
S22:Do not breathe dust.
S36/37:Wear suitable protective clothing and gloves.
WGK Germany : 2
RTECS : XH8300000

Amoxicillin Standards and Recommendations

Purity of amoxicillin: 98.00%

Amoxicillin Specification

Amoxicillin , its cas register number is 26787-78-0. It also can be called 6-(D-(-)-alpha-Amino-p-hydroxyphenylacetamido)penicillanic acid ; 6-(D-(-)-p-Hydroxy-alpha-aminobenzyl)penicillin ; 6-(p-Hydroxy-alpha-aminophenylacetamido)penicillanic acid ; Amoclen ; Amolin ; Amopenixin ; Amoxi ; Amoxi-Mast ;Amoxicaps ; Amoxicilina ; Amoxicillin pediatric ; Amoxicilline ; Amoxicillinum Amoxiden ; Amoxil ; Amoxivet ; D-(-)-alpha-Amino-p-hydroxybenzylpenicillin ; D-2-Amino-2-(4-hydroxyphenyl)acetamidopenicillanic acid ; D-Amoxicillin ; Delacillin ; DisperMox ; Hiconcil ; Histocillin ; Ibiamox ; Imacillin ; Larotid ; Metafarma capsules ; Metifarma capsules ; Moxacin ; Moxal ; Wymox ; alpha-Amino-p-hydroxybenzylpenicillin ; p-Hydroxyampicillin .

Product Name

Amoxicillin

Synthetic route

Amoxicillin Chemical Properties

Amoxicillin Uses

Amoxicillin Production

Amoxicillin Toxicity Data With Reference

Amoxicillin Safety Profile

Amoxicillin Standards and Recommendations

Amoxicillin Specification

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