Bromodichloromethane supplier

Name
Bromod ich loromethane
EINECS 200-856-7
CAS No. 75-27-4
Article Data43
CAS DataBase
Density 1.98 g/mL at 25 °C(lit.)
Solubility
Melting Point ?55 °C(lit.)
Formula CH Br Cl2
Boiling Point 87 °C(lit.)
Molecular Weight 163.829
Flash Point 1.3 °C
Transport Information
Appearance 2810
Safety Confirmed carcinogen with experimental carcinogenic data. Moderately toxic by ingestion. Human mutation data reported. When heated to decomposition it emits very toxic fumes of Br⁻ and Cl⁻. See also CHLORINATED HYDROCARBONS, ALIPHATIC; and BROMIDES.
Risk Codes 22-37/38-40-41
Molecular Structure
Hazard Symbols Xn
Synonyms Bromodichloromethane;Dichlorobromomethane; Dichloromonobromomethane; Monobromodichloromethane; NSC8018
PSA 0.00000
LogP 2.14250

Synthetic route

: 463-82-1
2,2-dimethylpropane

A: 3437-29-4
3,3-dimethylpyrrolidine-2,5-dione

B: 75-27-4
bromodichloromethane

C: 630-17-1
2,2-dimethylpropyl bromide

D: 82621-87-2
3-bromo-3-methylbutanoyl isocyanate

Conditions

Conditions	Yield
With ethene; dichloromethane; 22DMNBS; bromine at 12℃; for 30h; Irradiation; Further byproducts given. Yields of byproduct given;	A 67.7% B 32.3% C 45.2% D n/a

...Expand

: 67-66-3
chloroform

: 75-27-4
bromodichloromethane

Conditions

Conditions	Yield
With potassium hydroxide; sodium bromide; 18-crown-6 ether In water at 0℃; for 48h;	38%
With aluminium trichloride; hydrogen bromide
With aluminum tri-bromide; hydrogen bromide
With hydrogen bromide; aluminium

: 74-96-4
ethyl bromide

: 67-66-3
chloroform

: 75-27-4
bromodichloromethane

Conditions

Conditions	Yield
With aluminium trichloride at 20 - 25℃;

: 34557-54-5
methane

: 75-27-4
bromodichloromethane

Conditions

Conditions	Yield
With sulfur trioxide; sodium bromide; sodium chloride at 600 - 700℃;

: 75-09-2
dichloromethane

: 75-27-4
bromodichloromethane

Conditions

Conditions	Yield
With bromine at 220℃;
With N-Bromosuccinimide; bromine at 14 - 15℃;	0.50 mmol
With N-Bromosuccinimide at 15℃; Irradiation; competitive brominaton reactions with neopentane; further brominating systems (NBS-Br2; NBS-DCE);

: 67-66-3
chloroform

: 75-25-2
Bromoform

A: 75-27-4
bromodichloromethane

B: 124-48-1
chlorodibromomethane

Conditions

Conditions	Yield
With aluminium trichloride
at 135℃;
With sodium hydroxide In various solvent(s) Mechanism; Ambient temperature; effects of additives: p-dinitrobenzene and di-tert-butyl nitroxide;
With aluminium trichloride beim Erhitzen auf Siedetemperatur;
at 135℃; unter CO2-Druck;

...Expand

: 130292-39-6
2-bromo-2,2-dichloro-ethane-1,1-diol

: 75-27-4
bromodichloromethane

Conditions

Conditions	Yield
With potassium hydroxide

: 2648-61-5
2,2-dichloroacetophenone

: 75-27-4
bromodichloromethane

Conditions

Conditions	Yield
With hypobromite

: 463-82-1
2,2-dimethylpropane

: 82621-77-0
2,2-dimethyl-N-bromosuccinimide

A: 3437-29-4
3,3-dimethylpyrrolidine-2,5-dione

B: 75-27-4
bromodichloromethane

C: 630-17-1
2,2-dimethylpropyl bromide

D: 82621-87-2
3-bromo-3-methylbutanoyl isocyanate

Conditions

Conditions	Yield
With ethene; dichloromethane; bromine at 12℃; for 0.333333h; Irradiation; various molar ratios of educts; neopentane/methylene chloride competition with 2,2-dimethylsuccinimidyl radical; mechanism;

...Expand

: 463-82-1
2,2-dimethylpropane

: 75-27-4
bromodichloromethane

Conditions

Conditions	Yield
With N-Bromosuccinimide at 15℃; Irradiation; competition reaction with neopentane; relative rate constants for mediated brominations; additives - Br2, BrCCl3, CH2CCl2;

: 463-82-1
2,2-dimethylpropane

A: 75-27-4
bromodichloromethane

B: 630-17-1
2,2-dimethylpropyl bromide

Conditions

Conditions	Yield
With acetyl hypobromite; bromine In dichloromethane at -78℃; for 3h; Product distribution; Mechanism; Irradiation; other substrates;
With acetyl hypobromite; bromine In dichloromethane at -78℃; for 3h; Irradiation;

: 74-85-1
ethene

: 75-09-2
dichloromethane

: 594-11-6
methylcyclopropane

: 82621-80-5
2,2-dimethyl-N-bromoglutarimide

A: 5162-44-7
1-bromo-4-butene

B: 1194-33-8
2,2-dimethylglutarimide

C: 75-27-4
bromodichloromethane

D: N-(2-bromoethyl)-3,3-dimethylglutarimide

E: 106-93-4
ethylene dibromide

F: 7051-34-5
cyclopropylcarbinyl bromide

Conditions

Conditions	Yield
at 15℃; for 1h; Product distribution; Kinetics; Mechanism; Irradiation;	A 1.7 % Chromat. B 50.4 % Chromat. C 12.8 % Chromat. D 50.1 % Chromat. E 2.0 % Chromat. F 18.0 % Chromat.

...Expand

: 75-09-2
dichloromethane

: 594-11-6
methylcyclopropane

: 82621-80-5
2,2-dimethyl-N-bromoglutarimide

A: 5162-44-7
1-bromo-4-butene

B: 1194-33-8
2,2-dimethylglutarimide

C: 75-27-4
bromodichloromethane

D: 107-80-2
1,3-dibromobutane

E: 7051-34-5
cyclopropylcarbinyl bromide

Conditions

Conditions	Yield
at 15℃; for 1h; Product distribution; Mechanism; Kinetics; Irradiation;	A 3.2 % Chromat. B 95.9 % Chromat. C 24.1 % Chromat. D 8.5 % Chromat. E 34.5 % Chromat.

...Expand

: 75-09-2
dichloromethane

A: 75-27-4
bromodichloromethane

B: 67-66-3
chloroform

Conditions

Conditions	Yield
With bromine; chlorine In trichlorofluoromethane at 10℃; for 0.0166667h; Irradiation; Yield given;

: 67-66-3
chloroform

A: 75-27-4
bromodichloromethane

B: 124-48-1
chlorodibromomethane

Conditions

Conditions	Yield
With ethyl bromide; aluminum oxide; tetrabutyl phosphonium bromide at 170℃;	A 9.5 % Spectr. B 0.5 % Spectr.

: 67-66-3
chloroform

A: 75-27-4
bromodichloromethane

B: 124-48-1
chlorodibromomethane

C: 75-25-2
Bromoform

Conditions

Conditions	Yield
With carbon tetrabromide; tetranormalbutyl ammonium fluoride for 0.166667h; Product distribution; Mechanism; Ambient temperature; var. reag.: CBrCl3; equilibrium; products determined by GC-MS;

...Expand

: 75-25-2
Bromoform

A: 75-27-4
bromodichloromethane

B: 67-66-3
chloroform

C: 124-48-1
chlorodibromomethane

Conditions

Conditions	Yield
With dichloromethane; aluminum oxide; tetrabutyl phosphonium bromide at 170℃;	A 7 % Spectr. B 1 % Spectr. C 28 % Spectr.
With tetrachloromethane; tetranormalbutyl ammonium fluoride for 0.166667h; Product distribution; Mechanism; Ambient temperature; var.reag.: fluorotrichloromethane; equilibrium; products determined by GC-MS;

...Expand

: 75-25-2
Bromoform

A: 75-27-4
bromodichloromethane

B: 124-48-1
chlorodibromomethane

Conditions

Conditions	Yield
With sodium hydroxide; sodium chloride; N-benzyl-N,N,N-triethylammonium chloride In water Heating; Yield given. Yields of byproduct given;

: 75-62-7
Bromotrichloromethane

A: 75-27-4
bromodichloromethane

B: 67-66-3
chloroform

C: 67-72-1
hexachloroethane

Conditions

Conditions	Yield
With perchloric acid; CoW7-; sodium perchlorate In water; acetonitrile at 20℃; Rate constant; Product distribution; pH 7; reaction with Co(II)sepuchrate2- at 50 deg C; electron transfer reactions of polyhaloalkanes with Co(II)W12O407- and Co(II)sepulchrate2+, order of reactivity toward Co(II)W12O407-, trapping experiments with N-t-butyl-α-phenylnitrone;	A n/a B 72 % Spectr. C 2 % Spectr.

...Expand

: 74-85-1
ethene

: 75-09-2
dichloromethane

: 82621-80-5
2,2-dimethyl-N-bromoglutarimide

: 75-19-4
cyclopropane

A: 1194-33-8
2,2-dimethylglutarimide

B: 75-27-4
bromodichloromethane

C: 4333-56-6
cyclopropyl bromide

D: N-(2-bromoethyl)-3,3-dimethylglutarimide

Conditions

Conditions	Yield
Product distribution; Mechanism; Kinetics; Irradiation;	A n/a B 24 % Chromat. C 22 % Chromat. D 40 % Chromat.

...Expand

: 75-09-2
dichloromethane

: 75-19-4
cyclopropane

A: 75-27-4
bromodichloromethane

B: 4333-56-6
cyclopropyl bromide

Conditions

Conditions	Yield
With 2,2-dimethyl-N-bromoglutarimide Product distribution; Mechanism; Irradiation;	A 42 % Chromat. B 53 % Chromat.

...Expand

: 820-10-0
DL-methionine sulfone

: 16887-00-6
chloride

chloroperoxidase: chloroperoxidase

A: 75-27-4
bromodichloromethane

B: 67-66-3
chloroform

C: 124-48-1
chlorodibromomethane

D: 3018-12-0
dichloroacetonitrile

Conditions

Conditions	Yield
With dihydrogen peroxide; potassium carbonate In phosphate buffer sulfo-haloform reaction; Enzymatic reaction;

...Expand

: 16887-00-6
chloride

chloroperoxidase: chloroperoxidase

A: 75-27-4
bromodichloromethane

B: 67-66-3
chloroform

C: 124-48-1
chlorodibromomethane

D: 513-88-2
1,1-Dichloroacetone

Conditions

Conditions	Yield
With dihydrogen peroxide; potassium carbonate In phosphate buffer haloform reaction; Enzymatic reaction; Further byproducts given;

...Expand

: 56932-36-6
chloro bromomethyl

: 75-27-4
bromodichloromethane

Conditions

Conditions	Yield
With chlorine at 74.85 - 554.85℃; Rate constant; Kinetics;

: 504-15-4
orcinol

A: 75-27-4
bromodichloromethane

B: 67-66-3
chloroform

C: 124-48-1
chlorodibromomethane

D: 75-25-2
Bromoform

Conditions

Conditions	Yield
With sodium hypochlorite; sodium hypobromide for 1h; pH=8; Product distribution; Oxidation; halogenation;

...Expand

: 106-44-5
p-cresol

A: 75-27-4
bromodichloromethane

B: 67-66-3
chloroform

C: 124-48-1
chlorodibromomethane

D: 75-25-2
Bromoform

Conditions

Conditions	Yield
With sodium hypochlorite; sodium hypobromide for 1h; pH=8; Product distribution; Oxidation; halogenation;

...Expand

: 99-50-3
3,4-Dihydroxybenzoic acid

A: 75-27-4
bromodichloromethane

B: 67-66-3
chloroform

C: 124-48-1
chlorodibromomethane

D: 75-25-2
Bromoform

Conditions

Conditions	Yield
With sodium hypochlorite; sodium hypobromide for 1h; pH=8; Product distribution; Oxidation; halogenation;

...Expand

: 496-73-1
4-methyl resorcinol

A: 75-27-4
bromodichloromethane

B: 67-66-3
chloroform

C: 124-48-1
chlorodibromomethane

D: 75-25-2
Bromoform

Conditions

Conditions	Yield
With sodium hypochlorite; sodium hypobromide for 1h; pH=8; Product distribution; Oxidation; halogenation;

...Expand

: 89-86-1
4-hydroxysalicylic acid

A: 75-27-4
bromodichloromethane

B: 67-66-3
chloroform

C: 124-48-1
chlorodibromomethane

D: 75-25-2
Bromoform

Conditions

Conditions	Yield
With sodium hypochlorite; sodium hypobromide for 1h; pH=8; Product distribution; Oxidation; halogenation;

...Expand

: 95-71-6
2-methylbenzene-1,4-diol

A: 75-27-4
bromodichloromethane

B: 67-66-3
chloroform

C: 124-48-1
chlorodibromomethane

D: 75-25-2
Bromoform

Conditions

Conditions	Yield
With sodium hypochlorite; sodium hypobromide for 1h; pH=8; Product distribution; Oxidation; halogenation;

...Expand

: 75-27-4
bromodichloromethane

: 17598-03-7
5-ethenyl-1,2,4-trimethoxybenzene

: C12H15Cl2N3O3

Conditions

Conditions	Yield
With tris[2-(dimethylamino)ethyl]amine; trimethylsilylazide; copper hydroxide; potassium carbonate In methanol at 50℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;	98%

: 75-27-4
bromodichloromethane

: 2350-89-2
p-vinylbiphenyl

: C15H13Cl2N3

Conditions

Conditions	Yield
With tris[2-(dimethylamino)ethyl]amine; trimethylsilylazide; copper hydroxide; potassium carbonate In methanol at 50℃; for 12h; Catalytic behavior; Reagent/catalyst; Solvent; Temperature; Time; Schlenk technique; Inert atmosphere; Sealed tube; Large scale;	96%

: 30020-98-5
N-methyl-3-phenylindole

: 75-27-4
bromodichloromethane

: 321854-38-0
1-methyl-3-phenyl-1H-indole-2-carbaldehyde

Conditions

Conditions	Yield
Stage #1: N-methyl-3-phenylindole; bromodichloromethane With 1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate; palladium diacetate; acetic anhydride; silver carbonate In acetonitrile at 60℃; for 24h; Schlenk technique; Inert atmosphere; Stage #2: With hydrogenchloride In dichloromethane at 30℃;	95%

: 1073-67-2
4-vinylbenzyl chloride

: 75-27-4
bromodichloromethane

: 1-(1-azido-3,3-dichloropropyl)-4-chlorobenzene

Conditions

Conditions	Yield
With tris[2-(dimethylamino)ethyl]amine; trimethylsilylazide; copper hydroxide; potassium carbonate In methanol at 50℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;	94%

: 75-27-4
bromodichloromethane

: 36648-40-5
1-ethyl-3-phenyl-1H-indole

: C17H15NO

Conditions

Conditions	Yield
Stage #1: bromodichloromethane; 1-ethyl-3-phenyl-1H-indole With 1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate; palladium diacetate; acetic anhydride; silver carbonate In acetonitrile at 60℃; for 24h; Schlenk technique; Inert atmosphere; Stage #2: With hydrogenchloride In dichloromethane at 30℃;	93%

: 75-27-4
bromodichloromethane

: 1746-23-2
4-tert-Butylstyrene

: 1-(1-azido-3,3-dichloropropyl)-4-(tert-butyl)benzene

Conditions

Conditions	Yield
With tris[2-(dimethylamino)ethyl]amine; trimethylsilylazide; copper hydroxide; potassium carbonate In methanol at 50℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;	93%

: 626-20-0
3-methoxystyrene

: 75-27-4
bromodichloromethane

: C10H11Cl2N3O

Conditions

Conditions	Yield
With tris[2-(dimethylamino)ethyl]amine; trimethylsilylazide; copper hydroxide; potassium carbonate In methanol at 50℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;	93%

: 75-27-4
bromodichloromethane

: 151171-58-3
(8R,9S,13S,14S)-13-methyl-3-vinyl-6,7,8,9,11,12,13,14,15,16-decahydro-17H-cyclopenta[α]phenanthren-17-one

: C21H25Cl2N3O

Conditions

Conditions	Yield
With tris[2-(dimethylamino)ethyl]amine; copper hydroxide; potassium carbonate In methanol at 50℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;	92%

: 292638-84-7
styrene

: 75-27-4
bromodichloromethane

: (1-azido-3,3-dichloropropyl)benzene

Conditions

Conditions	Yield
With tris[2-(dimethylamino)ethyl]amine; trimethylsilylazide; copper hydroxide; potassium carbonate In methanol at 50℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;	91%

: 637-69-4
4-Methoxystyrene

: 75-27-4
bromodichloromethane

A: 1963-36-6
4-methoxycinnamaldehyde

B: 3,3-dichloro-1-(4-methoxyphenyl)propan-1-ol

Conditions

Conditions	Yield
Stage #1: 4-Methoxystyrene; bromodichloromethane With N,N,N',N'',N'''-pentamethyldiethylenetriamine; water; copper hydroxide; sodium iodide In acetonitrile at 40℃; for 24h; Inert atmosphere; Stage #2: With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide In ethyl acetate Catalytic behavior; Solvent; Reagent/catalyst;	A 9 %Spectr. B 90%
With N,N,N',N'',N'''-pentamethyldiethylenetriamine; copper hydroxide; potassium iodide In acetonitrile at 40℃; for 24h; Reagent/catalyst; Inert atmosphere;	A 31 %Spectr. B 2 %Spectr.

...Expand

: 2039-82-9
1-bromo-4-ethenyl-benzene

: 75-27-4
bromodichloromethane

: 1-(1-azido-3,3-dichloropropyl)-4-bromobenzene

Conditions

Conditions	Yield
With tris[2-(dimethylamino)ethyl]amine; trimethylsilylazide; copper hydroxide; potassium carbonate In methanol at 50℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;	90%

: 405-99-2
para-fluorostyrene

: 75-27-4
bromodichloromethane

: 1-(1-azido-3,3-dichloropropyl)-4-fluorobenzene

Conditions

Conditions	Yield
With tris[2-(dimethylamino)ethyl]amine; trimethylsilylazide; copper hydroxide; potassium carbonate In methanol at 50℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;	88%

: 75-27-4
bromodichloromethane

: 6175-14-0
1,1-bis-(4-fluorophenyl)ethene

: C15H11Cl2F2N3

Conditions

Conditions	Yield
With tris[2-(dimethylamino)ethyl]amine; trimethylsilylazide; copper hydroxide; potassium carbonate In methanol at 80℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;	88%

: 622-97-9
1-ethenyl-4-methylbenzene

: 75-27-4
bromodichloromethane

: 1504-75-2
3-(4-methylphenyl)acrylaldehyde

Conditions

Conditions	Yield
Stage #1: 1-ethenyl-4-methylbenzene; bromodichloromethane With N,N,N',N'',N'''-pentamethyldiethylenetriamine; water; copper hydroxide; sodium iodide In acetonitrile at 80℃; for 24h; Stage #2: With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide In ethyl acetate at 100℃; Inert atmosphere;	87%

: 622-97-9
1-ethenyl-4-methylbenzene

: 75-27-4
bromodichloromethane

: 1-(1-azido-3,3-dichloropropyl)-4-methylbenzene

Conditions

Conditions	Yield
With tris[2-(dimethylamino)ethyl]amine; trimethylsilylazide; copper hydroxide; potassium carbonate In methanol at 50℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;	87%

: 75-27-4
bromodichloromethane

: 4039-32-1
lithium hexamethyldisilazane

: 17067-99-1
(bromodichloromethyl)trimethylsilane

Conditions

Conditions	Yield
With chloro-trimethyl-silane at -78 - 20℃; Inert atmosphere;	86%

: 75-27-4
bromodichloromethane

: 23073-17-8
3-phenyl-1-(phenylmethyl)-1H-indole

: 1-benzyl-3-phenyl-1H-indole-2-carbaldehyde

Conditions

Conditions	Yield
Stage #1: bromodichloromethane; 3-phenyl-1-(phenylmethyl)-1H-indole With 1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate; palladium diacetate; acetic anhydride; silver carbonate In acetonitrile at 60℃; for 24h; Schlenk technique; Inert atmosphere; Stage #2: With hydrogenchloride In dichloromethane at 30℃;	86%

: 100-80-1
3-methylstyrene

: 75-27-4
bromodichloromethane

: C10H11Cl2N3

Conditions

Conditions	Yield
With tris[2-(dimethylamino)ethyl]amine; trimethylsilylazide; copper hydroxide; potassium carbonate In methanol at 50℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;	86%

: 75-27-4
bromodichloromethane

: 98-83-9
isopropenylbenzene

: 1-azido-1-methyl-3,3-dichloropropylbenzene

Conditions

Conditions	Yield
With tris[2-(dimethylamino)ethyl]amine; trimethylsilylazide; copper hydroxide; potassium carbonate In methanol at 80℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;	86%

: 1,5-dimethyl-3-phenyl-1H-indole

: 75-27-4
bromodichloromethane

: C17H15NO

Conditions

Conditions	Yield
Stage #1: 1,5-dimethyl-3-phenyl-1H-indole; bromodichloromethane With 1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate; palladium diacetate; acetic anhydride; silver carbonate In acetonitrile at 60℃; for 24h; Schlenk technique; Inert atmosphere; Stage #2: With hydrogenchloride In dichloromethane at 30℃;	85%

: 30020-98-5
N-methyl-3-phenylindole

: 75-27-4
bromodichloromethane

: 108-24-7
acetic anhydride

: C20H19NO4

Conditions

Conditions	Yield
With 1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate; palladium diacetate; silver carbonate In acetonitrile at 60℃; for 24h; Schlenk technique; Inert atmosphere;	85%

...Expand

: 75-27-4
bromodichloromethane

: 2351-50-0
4-iodostyrene

: C9H8Cl2IN3

Conditions

Conditions	Yield
With tris[2-(dimethylamino)ethyl]amine; trimethylsilylazide; copper hydroxide; potassium carbonate In methanol at 50℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;	84%

: 75-27-4
bromodichloromethane

: 18760-11-7
4-methythiostyrene

: C10H11Cl2N3S

Conditions

Conditions	Yield
With tris[2-(dimethylamino)ethyl]amine; trimethylsilylazide; copper hydroxide; potassium carbonate In methanol at 50℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;	84%

: 75-27-4
bromodichloromethane

: 579-71-5
2-nitrostyrene

: C9H8Cl2N4O2

Conditions

Conditions	Yield
With tris[2-(dimethylamino)ethyl]amine; trimethylsilylazide; copper hydroxide; potassium carbonate In methanol at 80℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;	84%

: 778-66-5
1,1-diphenyl-1-propene

: 75-27-4
bromodichloromethane

: 1213-69-0
2-methyl-3,3-diphenylpropenal

Conditions

Conditions	Yield
Stage #1: 1,1-diphenyl-1-propene; bromodichloromethane With N,N,N',N'',N'''-pentamethyldiethylenetriamine; water; copper hydroxide; sodium iodide In acetonitrile at 80℃; for 24h; Stage #2: With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide In ethyl acetate at 100℃; Inert atmosphere;	83%

: 75-27-4
bromodichloromethane

: 5338-96-5
3-cyanostyrene

: C10H8Cl2N4

Conditions

Conditions	Yield
With tris[2-(dimethylamino)ethyl]amine; trimethylsilylazide; copper hydroxide; potassium carbonate In methanol at 50℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;	83%

: 75-27-4
bromodichloromethane

: C16H15N

: C17H15NO

Conditions

Conditions	Yield
Stage #1: bromodichloromethane; C16H15N With 1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate; palladium diacetate; acetic anhydride; silver carbonate In acetonitrile at 60℃; for 24h; Schlenk technique; Inert atmosphere; Stage #2: With hydrogenchloride In dichloromethane at 30℃;	82%

: 75-27-4
bromodichloromethane

: 402-50-6
1-trifluoromethyl-4-vinyl-benzene

: C10H8Cl2F3N3

Conditions

Conditions	Yield
With tris[2-(dimethylamino)ethyl]amine; trimethylsilylazide; copper hydroxide; potassium carbonate In methanol at 50℃; for 12h; Schlenk technique; Inert atmosphere; Sealed tube;	82%

: 75-27-4
bromodichloromethane

: 7677-24-9
trimethylsilyl cyanide

: 2350-89-2
p-vinylbiphenyl

: C16H13Cl2N

Conditions

Conditions	Yield
With tert.-butylhydroperoxide In acetone at 20℃; for 24h; Alkaline conditions; Inert atmosphere;	82%

...Expand

: 75-27-4
bromodichloromethane

: 23974-72-3
sodium phenylselenide

: 134480-05-0
1,1-dichloro-1-phenylseleno methane

Conditions

Conditions	Yield
In ethanol	81%

Bromodichloromethane Chemical Properties

Bromodichloromethane ,its CAS register number is 75-27-4,it's called for Bdcm ; Bromdichlormethan ; Bromodichloro-methan ; Bromodichoromethane ; CHBrCl₂ ; Dichloromonobromomethane ; Methane,bromodichloro- ; Monobromodichloromethane ; Bromo(dichloro)methane ,and so on. Bromodichloromethane (CAS No.75-27-4) is commonly clear colorless to yellowish liquid.

IUPAC Name: Bromo(dichloro)methane
CAS: 75-27-4
Molecular Formula: CHBrCl₂
Molecular Weight: 163.83
molecular structure:
EINECS: 200-856-7
Melting point: −55 °C(lit.)
Storage temp.: 0-6°C
Merck: 14,1417
BRN: 1697005
ACD/LogD (pH 5.5): 2.02
ACD/LogD (pH 7.4): 2.02
ACD/BCF (pH 5.5): 20.23
ACD/BCF (pH 7.4): 20.23
ACD/KOC (pH 5.5): 299.54
ACD/KOC (pH 7.4): 299.54
H bond acceptors: 0
H bond donors: 0
Freely Rotating Bonds: 0
Index of Refraction: 1.503
Molar Refractivity: 24.07 cm³
Molar Volume: 81.3 cm³
Polarizability: 9.54 10^-24cm³
Surface Tension: 35.3 dyne/cm
Density: 2.013 g/cm³
Flash Point: 1.3 °C
Enthalpy of Vaporization: 31.61 kJ/mol
Boiling Point: 89.7 °C at 760 mmHg
Vapour Pressure: 65.3 mmHg at 25°C

Bromodichloromethane Uses

1. Bromodichloromethane (CAS No.75-27-4) is commonly used as standard reagent for analysis.
2. Bromodichloromethane (CAS No.75-27-4) has been formerly used as a flame retardant, solvent for fats and waxes.
3. Now Bromodichloromethane (CAS No.75-27-4) is used as a reagent or intermediate in organic chemistry.

Bromodichloromethane Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	oral	450mg/kg (450mg/kg)	BRAIN AND COVERINGS: "CHANGES IN CIRCULATION (HEMORRHAGE, THROMBOSIS, ETC.)" LIVER: FATTY LIVER DEGERATION BLOOD: HEMORRHAGE	Toxicology and Applied Pharmacology. Vol. 44, Pg. 213, 1978.
rat	LD50	oral	430mg/kg (430mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: TREMOR LIVER: OTHER CHANGES	Science Reports of the Research Institutes, Tohoku University, Series C: Medicine. Vol. 36(1-4), Pg. 10, 1989.

RTECS: PA5310000

Bromodichloromethane Consensus Reports

NTP 10th Report on Carcinogens. NTP Carcinogenesis Studies (gavage); Clear Evidence: rat, mouse NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No. NTP-TR-321 (1987). . EPA Genetic Toxicology Program. Community Right-To-Know List. Reported in EPA TSCA Inventory.

Bromodichloromethane Safety Profile

Confirmed carcinogen with experimental carcinogenic data. Moderately toxic by ingestion. Human mutation data reported. When heated to decomposition it emits very toxic fumes of Br⁻ and Cl⁻.

Hazard Codes: Xn,T,F
Risk Statements: 22-37/38-40-41-39/23/24/25-23/24/25-11 (R22:Harmful if swallowed. R37/38:Irritating to respiratory system and skin. R40:Limited evidence of a carcinogenic effect. R41:Risk of serious damage to the eyes. R39:Danger of very serious irreversible effects. R23/24/25:Toxic by inhalation, in contact with skin and if swallowed. R11:Highly flammable.)
Safety Statements: 26-36/39-45-36/37-16-36/37/39 (S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.S36:Wear suitable protective clothing. S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37:Wear suitable protective clothing and gloves. S16:Keep away from sources of ignition. S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.)
RIDADR: 2810
WGK Germany: 3
F: 8
HazardClass: 6.1
PackingGroup: III

Bromodichloromethane Specification

Removal in wastewater treatment of Bromodichloromethane (CAS No.75-27-4) can be stated as follows:
Total removal:46.99 percent
Total biodegradation:0.06 percent
Total sludge adsorption:1.38 percent
Total to Air:45.55 percent
(using 10000 hr Bio P,A,S)

Product Name

Bromod ich loromethane

Synthetic route

Bromodichloromethane Chemical Properties

Bromodichloromethane Uses

Bromodichloromethane Toxicity Data With Reference

Bromodichloromethane Consensus Reports

Bromodichloromethane Safety Profile

Bromodichloromethane Specification

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