Butyldiglycol supplier | CasNO.112-34-5

Name
Butyldiglycol
EINECS 203-961-6
CAS No. 112-34-5
Article Data25
CAS DataBase
Density 0.949 g/cm³
Solubility soluble
Melting Point -68 °C(lit.)
Formula C₈H₁₈O₃
Boiling Point 230.4 °C at 760 mmHg
Molecular Weight 162.229
Flash Point 100 °C
Transport Information
Appearance colourless liquid
Safety 24-26
Risk Codes 36
Molecular Structure
Hazard Symbols Xi
Synonyms 2-(2-Butoxyethoxy)ethanol;2-(2-n-Butoxyethoxy)ethanol;3,6-Dioxa-1-decanol;BDG;BDG-NS;BDGE 20;BikanolB 2;Butadigol;Butoxyethoxyethanol;Butycenol 20P;Butyl Carbitol;ButylDiglysolv;Butyl Oxitol glycol ether;Butyl digol;Diethylene glycol butylether;Diethylene glycol mono-n-butyl ether;Diethylene glycol monobutyl ether;Ethanol, 2,2'-oxybis-, monobutyl ether;
PSA 38.69000
LogP 0.81200

Synthetic route

: 75-21-8
oxirane

: 71-36-3
butan-1-ol

A: 111-76-2
2-Butoxyethanol

B: 112-34-5
Diethylene glycol monobutyl ether

Conditions

Conditions	Yield
With potassium aluminum sulfate at 170℃; for 24h; Reagent/catalyst; Autoclave;	A 93.1% B 6.63%

...Expand

: 109-69-3
n-Butyl chloride

: 111-46-6
diethylene glycol

: 112-34-5
Diethylene glycol monobutyl ether

Conditions

Conditions	Yield
With sodium hydroxide; water at 100℃; for 24h;	70%

: 75-21-8
oxirane

: 71-36-3
butan-1-ol

: 112-34-5
Diethylene glycol monobutyl ether

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate at 50℃;

: 71-36-3
butan-1-ol

: 111-46-6
diethylene glycol

: 112-34-5
Diethylene glycol monobutyl ether

Conditions

Conditions	Yield
sulfuric acid In toluene Heating;

: 109-65-9
1-bromo-butane

sodium diethylene glycolate: sodium diethylene glycolate

: 112-34-5
Diethylene glycol monobutyl ether

Conditions

Conditions	Yield
With diethylene glycol

: 75-21-8
oxirane

: 71-36-3
butan-1-ol

A: 111-76-2
2-Butoxyethanol

B: 112-34-5
Diethylene glycol monobutyl ether

C: 143-22-6
triethyleneglycol monobutyl ether

Conditions

Conditions	Yield
2,4,6-trimethyl-pyridine at 160℃; under 2311.54 - 3345.86 Torr; for 2.5h; Product distribution / selectivity; Inert atmosphere;
sodium butanolate at 140℃; under 7500.75 Torr; for 5h; Product distribution / selectivity;	A 20.16 %Chromat. B 9.07 %Chromat. C 6.10 %Chromat.
catalyst of invention (Sb2O3, copper acetate, hydrogen peroxide; calcined) at 140℃; under 30003 Torr; for 24 - 120h; Product distribution / selectivity;	A 76 - 77 %Chromat. B 13 - 14 %Chromat. C 9 %Chromat.

...Expand

: 129-00-0
pyrene

A: 85-44-9
phthalic anhydride

B: 90-47-1
xanth-9-one

C: 629-62-9
pentadecane

D: 629-97-0
n-docosane

E: 630-01-3
n-hexacosane

F: 629-59-4
tetradecane

G: 544-76-3
Hexadecane

H: 112-34-5
Diethylene glycol monobutyl ether

I: 97-87-0
n-butyl isobutyrate

J: 629-94-7
heneicosane

K: 638-67-5
n-tricosane

L: 646-31-1
tetracosane

M: 629-99-2
n-pentacosane

N: 203-63-4
cyclopenta[def]phenanthrene

O: 1,2-benzenedicarboxylic acid diisooctyl ether

P: 128-37-0
2,6-di-tert-butyl-4-methyl-phenol

Q: 84-66-2
Diethyl phthalate

R: 84-74-2
Phthalic acid dibutyl ester

S: 203-64-5
4H-Cyclopenta[def]phenanthrene

T: 85-68-7
benzyl n-butyl phthalate

U: 4371-26-0
1,1'-Biphenyl-2,2',6,6'-tetracarboxaldehyde

V: 16162-34-8
4,5-phenanthrene-8,9-dicarbaldehyde

W: 57-10-3
1-hexadecylcarboxylic acid

X: 6-propyltridecane

Conditions

Conditions	Yield
With oxygen; ozone In water for 0.25 - 2h;

...Expand

: 112-60-7
Tetraethylene glycol

: 107-21-1
ethylene glycol

: 123-72-8
butyraldehyde

: 111-46-6
diethylene glycol

: 112-27-6
2,2'-[1,2-ethanediylbis(oxy)]bisethanol

A: 3390-13-4
2-propyl-1,3-dioxolane

B: 111-76-2
2-Butoxyethanol

C: 112-34-5
Diethylene glycol monobutyl ether

D: 143-22-6
triethyleneglycol monobutyl ether

E: 1559-34-8
tetraethylene glycol monobutyl ether

F: 71-36-3
butan-1-ol

Conditions

Conditions	Yield
With hydrogen; palladium 10% on activated carbon at 180℃; under 51716.2 Torr; for 2h;

...Expand

: 123-72-8
butyraldehyde

: 111-46-6
diethylene glycol

: 112-34-5
Diethylene glycol monobutyl ether

Conditions

Conditions	Yield
With hydrogen; palladium 10% on activated carbon at 200℃; under 51716.2 Torr; for 2h; Inert atmosphere;	94.5 %Chromat.
With palladium 10% on activated carbon; hydrogen at 200℃; under 51755.2 Torr; for 2h;	94.5 %Chromat.

: 112-34-5
Diethylene glycol monobutyl ether

: 98-59-9
p-toluenesulfonyl chloride

: 50964-16-4
diethylene glycol monobutyl ether tosylate

Conditions

Conditions	Yield
Stage #1: Diethylene glycol monobutyl ether; p-toluenesulfonyl chloride With dmap In dichloromethane at 20℃; Stage #2: With triethylamine In dichloromethane at 20℃;	100%
With sodium hydroxide In tetrahydrofuran; water at 0℃; for 2h;	85%
With pyridine In dichloromethane at 20℃; for 3h;	57%
With pyridine

: 112-34-5
Diethylene glycol monobutyl ether

: 25354-97-6
2-hexyldecanoic acid

: 2-(2-butoxyethoxy)ethyl 2-hexyldecanoate

Conditions

Conditions	Yield
With p-toluenesulfonic acid monohydrate	99%
With p-toluenesulfonic acid monohydrate	99%

: 112-34-5
Diethylene glycol monobutyl ether

: 110-42-9
Methyl decanoate

: 112-30-1
1-Decanol

Conditions

Conditions	Yield
With sodium borohydrid In 5,5-dimethyl-1,3-cyclohexadiene	98%

: 112-34-5
Diethylene glycol monobutyl ether

: 598-21-0
2-Bromoacetyl bromide

: 56521-78-9
2-(2-butoxyethoxy)ethyl 2-bromoacetate

Conditions

Conditions	Yield
With sodium carbonate In dichloromethane at -5 - 20℃; for 12h; Green chemistry;	98%
With triethylamine In dichloromethane at -78℃; Inert atmosphere;	72%

: 112-34-5
Diethylene glycol monobutyl ether

: 107-13-1
acrylonitrile

: 35633-48-8
3-[2-(2-butoxyethoxy)ethoxy]propanenitrile

Conditions

Conditions	Yield
With sodium methylate for 1.16667h;	97%

: 124-04-9
Adipic acid

: 111-77-3
2-(2-methoxyethoxy)ethyl alcohol

: 112-34-5
Diethylene glycol monobutyl ether

: methyldiglycol butyldiglycol adipate

Conditions

Conditions	Yield
toluene-4-sulfonic acid In toluene at 118 - 145℃; for 6.5h; Heating / reflux;	96.9%

...Expand

: 112-34-5
Diethylene glycol monobutyl ether

: 123-63-7
paracetaldehyde

: 3895-17-8
2-butoxyethyl 2-ethoxyethyl ether

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal at 160℃; under 760 Torr; for 18h; Etherification;	96%
With hydrogen; palladium on activated charcoal at 160℃; for 10h; atmospheric pressure;	96%

: 112-34-5
Diethylene glycol monobutyl ether

: 1120-23-6
1-[2-(2-chloroethoxy)-ethoxy]butane

Conditions

Conditions	Yield
With pyridine; thionyl chloride In chloroform for 10h; Reflux;	95%
With pyridine; thionyl chloride

: 112-34-5
Diethylene glycol monobutyl ether

: 124-13-0
Octanal

: 101433-27-6
2-butoxyethyl 2-(octoxy)ethyl ether

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal at 160℃; under 760 Torr; for 18h; Etherification;	95%
With hydrogen; palladium on activated charcoal at 160℃; for 10h; atmospheric pressure;	95%

: 112-34-5
Diethylene glycol monobutyl ether

: 2258-42-6
Acetic formic anhydride

: 2-(2-butoxyethoxy)ethyl formate

Conditions

Conditions	Yield
With pyridine 1.) 0 deg C, 5 h, 2.) rt, 12 h;	90%

: 112-34-5
Diethylene glycol monobutyl ether

: 1121-22-8, 1436-59-5, 20439-47-8, 21436-03-3, 41013-43-8, 694-83-7
trans-1,2-Diaminocyclohexane

: C38H74N6O10

Conditions

Conditions	Yield
Stage #1: Diethylene glycol monobutyl ether; Hexamethylene diisocyanate; dibutyltin dilaurate In hexane at 20 - 45℃; Stage #2: trans-1,2-Diaminocyclohexane In hexane at 15 - 20℃; for 0.5h;	88.8%

: 112-34-5
Diethylene glycol monobutyl ether

: 626-00-6
1,3-Diiodobenzene

: 71784-21-9
1,3-Bis-[2-(2-butoxy-ethoxy)-ethoxy]-benzene

Conditions

Conditions	Yield
With copper(l) iodide; 1,10-Phenanthroline; caesium carbonate In 5,5-dimethyl-1,3-cyclohexadiene for 20h; Reflux; Inert atmosphere;	86%

: 50-00-0
formaldehyd

: 112-34-5
Diethylene glycol monobutyl ether

: 118600-20-7, 134731-86-5
rccc-2,8,14,20-tetrakis-(iso-butyl)-resorcin[4]arene

: C80H128O20

Conditions

Conditions	Yield
With iminodiacetic acid In acetonitrile	81%

...Expand

: 112-34-5
Diethylene glycol monobutyl ether

: 7727-18-6
vanadium(V) oxychloride

: dichloro(2-(2-butoxyethoxy)ethanolate)oxovanadium(V)

Conditions

Conditions	Yield
In pentane byproducts: HCl; N2, equimol., V compd. added dropwise to a soln. of alcohol, stirred for2 h, heated on water bath; decanted, concd., stored at 0°C, ppt. collected, dried (vac.); elem. anal.;	80%

: 112-34-5
Diethylene glycol monobutyl ether

: 90-14-2
1-Iodonaphthalene

: 1-(2-(2-butoxyethoxy)ethoxy)naphthalene

Conditions

Conditions	Yield
With copper(l) iodide; 1,10-Phenanthroline; caesium carbonate In 5,5-dimethyl-1,3-cyclohexadiene at 145℃; for 26h; Inert atmosphere;	79%
With copper(l) iodide; 1,10-Phenanthroline; caesium carbonate In 5,5-dimethyl-1,3-cyclohexadiene at 145℃; for 26h; Inert atmosphere;	79%

: 112-34-5
Diethylene glycol monobutyl ether

: 34713-70-7
2-Phenylpropanal

: (E/Z)-(1-(2-(2-butoxyethoxy)ethoxy)prop-1-en-2-yl)benzene

Conditions

Conditions	Yield
With methanesulfonic acid; methanesulfonic acid sodium salt In toluene for 15h; Inert atmosphere; Reflux; Dean-Stark;	79%

: 112-34-5
Diethylene glycol monobutyl ether

: 31250-16-5
[2-(2-chloro-2-oxoethoxy)phenoxy]acetyl chloride

: Dibutoxyethoxyethyl 1,2-phenylenedioxydiacetate

Conditions

Conditions	Yield
In tetrachloromethane Ambient temperature;	76%

: 1938-32-5
5-(chloromethyl)-6-propyl-1,3-benzodioxole

: 112-34-5
Diethylene glycol monobutyl ether

: 51-03-6
Piperonyl butoxide

Conditions

Conditions	Yield
Stage #1: Diethylene glycol monobutyl ether With sodium hydroxide In water Reflux; Stage #2: 5-(chloromethyl)-6-propyl-1,3-benzodioxole In water for 5h; Reflux;	75%
With sodium hydroxide at 30℃; for 5h;	230 g

: 112-34-5
Diethylene glycol monobutyl ether

: 615-42-9
1,2-Diiodobenzene

: 71784-20-8
1,2-bis(2-(2-(butyloxy)ethoxy)ethoxy)benzene

Conditions

Conditions	Yield
With copper(l) iodide; 1,10-Phenanthroline; caesium carbonate In 5,5-dimethyl-1,3-cyclohexadiene for 40h; Reflux; Inert atmosphere;	75%
With copper(l) iodide; 1,10-Phenanthroline; caesium carbonate In 5,5-dimethyl-1,3-cyclohexadiene at 140℃; for 24h; Inert atmosphere;	4 g

: 117-80-6
2,3-Dichloro-1,4-naphthoquinone

: 112-34-5
Diethylene glycol monobutyl ether

: C26H38O8

Conditions

Conditions	Yield
With NAH In tetrahydrofuran at 80℃; Inert atmosphere;	71%

: 112-34-5
Diethylene glycol monobutyl ether

: 40926-73-6
2-(2-methoxyphenoxy)acetyl chloride

: Butoxyethoxyethyl o-methoxyphenoxyacetate

Conditions

Conditions	Yield
In chloroform for 12h; Heating;	69.01%

: 112-34-5
Diethylene glycol monobutyl ether

: 103781-33-5
3-{[(4-bromobutyl)oxy]methyl}-3-methyloxetane

: 3-(2,7,10,13-tetraoxaheptadecyl)-3-methyloxetane

Conditions

Conditions	Yield
With sodium hydroxide; tetrabutylammomium bromide In hexane for 5h; Heating;	68%

: 38020-81-4
2-iodoacetyl chloride

: 112-34-5
Diethylene glycol monobutyl ether

: 56521-91-6
2-(2-butoxyethoxy)ethyl-2-iodoacetate

Conditions

Conditions	Yield
With sodium carbonate In dichloromethane at -5 - 20℃; for 12h; Green chemistry;	68%

: 112-34-5
Diethylene glycol monobutyl ether

: 20142-87-4
2-(2-nitrophenoxy)acetyl chloride

: Butoxyethoxyethyl o-nitrophenoxyacetate

Conditions

Conditions	Yield
In chloroform for 12h; Heating;	66.89%

: 940-71-6
2,2,4,4,6,6-hexachloro-1,3,5-triaza-2,4,6-triphosphorine

: 112-34-5
Diethylene glycol monobutyl ether

A: 1245625-50-6
C24H51Cl3N3O9P3

B: 1245625-47-1
C24H51Cl3N3O9P3

C: 1245625-36-8
C24H51Cl3N3O9P3

Conditions

Conditions	Yield
With sodium hydride In tetrahydrofuran at -60 - 20℃; for 3.5h; Inert atmosphere;	A 20% B 16% C 64%

...Expand

: 112-34-5
Diethylene glycol monobutyl ether

A: 1245625-50-6
C24H51Cl3N3O9P3

B: 1245625-47-1
C24H51Cl3N3O9P3

C: 1245625-36-8
C24H51Cl3N3O9P3

Conditions

Conditions	Yield
With 2,2,4,4,6,6-hexachloro-1,3,5-triaza-2,4,6-triphosphorine; sodium hydride In tetrahydrofuran at -60 - 20℃; for 3.5h; Inert atmosphere;	A 20% B 16% C 64%
With 2,2,4,4,6,6-hexachloro-1,3,5-triaza-2,4,6-triphosphorine; sodium hydride In tetrahydrofuran at -60 - 20℃; for 3.5h; Inert atmosphere;	A 20% B 16% C 64%

...Expand

: 112-34-5
Diethylene glycol monobutyl ether

: (5,10,15,20-tetraphenylporphinato)dichlorophosphorus(V) chloride

: di(3,6-dioxadecyloxo)tetraphenylporphyrinatophosphorus(V) chloride

Conditions

Conditions	Yield
With pyridine In acetonitrile for 24h; Reflux;	60%
With pyridine In acetonitrile for 24h; Reflux;

: 112-34-5
Diethylene glycol monobutyl ether

: 2-methyl-2-octyldodecanoic acid

: C29H58O4

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In toluene for 18h; Dean-Stark; Reflux;	60%

Butyldiglycol Consensus Reports

DIETHYLENE GLYCOL MONOBUTYL ETHER is reported in EPA TSCA Inventory. Glycol ether compounds are on the Community Right-To-Know List.

Butyldiglycol Standards and Recommendations

DFG MAK: 100 mg/m³

Butyldiglycol Specification

The Diethylene glycol monobutyl ether with CAS registry number of 112-34-5 is also called Ethanol,2-(2-butoxyethoxy)-. The IUPAC name is 2-(2-butoxyethoxy)ethanol. Its EINECS registry number is 203-961-6. In addition, the molecular formula is C₈H₁₈O₃ and the molecular weight is 162.23. It is a kind of colourless liquid with a mild odour and belongs to the classes of Ethylene Glycols Monofunctional Ethylene Glycols and Monofunctional Ethylene Glycols. And it is stable and incompatible with strong oxidizing agents and strong bases.

Physical properties about this chemical are: (1)ACD/LogP: 0.44; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.44; (4)ACD/LogD (pH 7.4): 0.44; (5)ACD/BCF (pH 5.5): 1.27; (6)ACD/BCF (pH 7.4): 1.27; (7)ACD/KOC (pH 5.5): 41.26; (8)ACD/KOC (pH 7.4): 41.26; (9)#H bond acceptors: 3; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 9; (12)Polar Surface Area: 38.69 Å²; (13)Index of Refraction: 1.43; (14)Molar Refractivity: 44.13 cm³; (15)Molar Volume: 170.8 cm³; (16)Polarizability: 17.49 ×10^-24cm³; (17)Surface Tension: 32 dyne/cm; (18)Density: 0.949 g/cm³; (19)Flash Point: 100 °C; (20)Enthalpy of Vaporization: 54.29 kJ/mol; (21)Boiling Point: 230.4 °C at 760 mmHg; (22)Vapour Pressure: 0.0126 mmHg at 25°C.

Preparation of Diethylene glycol monobutyl ether: it can be prepared by butanol and ethyl ether boron trifluoride. This reaction will need reagent epoxyethane. The reaction time is 2-3 hours at reaction temperature of 75-80 °C. After the reaction, use butanol sodium to make pH into 8, then put it into the distillation tower for distillation.

Diethylene glycol monobutyl ether can be prepared by butanol and ethyl ether boron trifluoride

Uses of Diethylene glycol monobutyl ether: it can be used as solvent of nitrocellulose, varnish, printing ink, the oil ans the resin. It also can be used for adhesive thinner and emulsioni paint stabilizer. In addition, it can react with (2-methoxy-phenoxy)-acetyl chloride to get Butoxyethoxyethyl o-methoxyphenoxyacetate. This reaction will need reagent CHCl₃. The reaction time is 21 hours by heating. The yield is about 69.01%.

Diethylene glycol monobutyl ether can react with (2-methoxy-phenoxy)-acetyl chloride to get Butoxyethoxyethyl o-methoxyphenoxyacetate

When you are using this chemical, please be cautious about it as the following:
It is irritating to the eyes. during using it, avoid contact with skin. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES:CCCCOCCOCCO
(2)InChI:InChI=1/C8H18O3/c1-2-3-5-10-7-8-11-6-4-9/h9H,2-8H2,1H3
(3)InChIKey:OAYXUHPQHDHDDZ-UHFFFAOYAO

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	oral	2gm/kg (2000mg/kg)	BEHAVIORAL: GENERAL ANESTHETIC GASTROINTESTINAL: OTHER CHANGES KIDNEY, URETER, AND BLADDER: OTHER CHANGES	Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.
mouse	LD50	intraperitoneal	850mg/kg (850mg/kg)	LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" BLOOD: CHANGES IN SPLEEN	Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 6, Pg. 342, 1947.
mouse	LD50	oral	2400mg/kg (2400mg/kg)		Journal of the American College of Toxicology. Vol. 12, Pg. 139, 1993.
mouse	LD50	unreported	6050mg/kg (6050mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(2), Pg. 14, 1981.
rabbit	LD50	oral	2200mg/kg (2200mg/kg)		"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 3964, 1982.
rabbit	LD50	skin	2700mg/kg (2700mg/kg)		Journal of the American College of Toxicology. Vol. 12, Pg. 139, 1993.
rat	LD50	oral	5660mg/kg (5660mg/kg)		Dow Chemical Company Reports. Vol. MSD-41,
rat	LD50	unreported	4500mg/kg (4500mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 46(2), Pg. 14, 1981.

Product Name

Butyldiglycol

Synthetic route

Butyldiglycol Consensus Reports

Butyldiglycol Standards and Recommendations

Butyldiglycol Specification

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