Chromium trioxide supplier | CasNO.1333-82-0

Name
Chromium(VI) trioxide
EINECS 215-607-8
CAS No. 1333-82-0
Article Data2
CAS DataBase
Density 2.7 g/cm³
Solubility Highly soluble in water
Melting Point 196 °C
Formula CrO₃
Boiling Point 330 °C
Molecular Weight 99.9942
Flash Point 250°C
Transport Information UN 1463 5.1/PG 2
Appearance dark red crystals or powder
Safety 53-45-60-61-36/37/39-28-26-22
Risk Codes 45-46-9-24/25-26-35-42/43-48/23-50/53-62-8
Molecular Structure
Hazard Symbols O,T+,N
Synonyms Chromia(CrO₃);Chromic anhydride;Chromic trioxide;Chromiumtrioxide;Chromium(VI) oxide;Chromium(VI) trioxide;Monochromium trioxide;Chromiun(Ⅵ)oxide;
PSA 51.21000
LogP -0.35640

Synthetic route

: 7440-47-3
chromium

: 80937-33-3
oxygen

: 1333-82-0
chromium(VI) oxide

Conditions

Conditions	Yield
In gaseous matrix laser-vaporized Cr atoms; O2 seeded in He; underwent supersonic expansion;

: chromium chloride

: 7732-18-5
water

: 1333-82-0
chromium(VI) oxide

Conditions

Conditions	Yield
Stage #1: chromium chloride; water With ammonia pH=7.5; Stage #2: at 300℃; for 8h; Calcination;

: 1333-82-0
chromium(VI) oxide

: 175424-48-3
3-methyl-6-benzyloxazolo[4,5-b]pyridin-2(3H)-one

: 175424-00-7
3-methyl-6-benzoyloxazolo[4,5-b]pyridin-2(3H)-one

Conditions

Conditions	Yield
With tert.-butylhydroperoxide In dichloromethane	82%

: 4926-28-7
2-Bromo-4-picoline

: 1333-82-0
chromium(VI) oxide

: 66572-56-3
2-bromoisonicotinic acid

Conditions

Conditions	Yield
In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; sulfuric acid	82%

3N-HCl: 3N-HCl

: 14495-51-3
2-bromo-5-chlorotoluene

: 1333-82-0
chromium(VI) oxide

: 174265-12-4
2-bromo-5-chlorobenzaldehyde

Conditions

Conditions	Yield
With sulfuric acid In ethanol; water; acetic anhydride	77%

...Expand

: 333995-39-4
2-[2,6-dichloro-4-(trifluoromethyl)phenyl]-5,6-difluoro-2,4,5,6-tetrahydrocyclopenta[c]pyrazole

: 1333-82-0
chromium(VI) oxide

: 333995-42-9
2-[2,6-dichloro-4-(trifluoromethyl)phenyl]-5,6-difluoro-5,6-dihydrocyclopenta[c]pyrazol-4-one

Conditions

Conditions	Yield
In hexane; acetic acid; ethyl acetate	76%

: 7647-01-0
hydrogenchloride

: 91-63-4
2-methylquinoline

: 1333-82-0
chromium(VI) oxide

: quinaldinium chlorochromate

Conditions

Conditions	Yield
In water at 0℃; for 2.5h;	72%

...Expand

: 1333-82-0
chromium(VI) oxide

: 100991-28-4
1,11-dihydroxy-3-dodecyne

: 87519-39-9
11-hydroxy-3-dodecynoic acid

Conditions

Conditions	Yield
In hexane; sulfuric acid; water; acetone	68%

: 1607-17-6
pentrinitrol

: 1333-82-0
chromium(VI) oxide

: 67406-79-5
2-Nitryloxy-2,2-bis(nitryloxymethyl)propionsaeure

Conditions

Conditions	Yield
With sulfuric acid	60%

: 333995-54-3
2-[2,6-dichloro-4-(trifluoromethyl)phenyl]-5,5-difluoro-2,4,5,6-tetrahydrocyclopenta[c]pyrazole

: 1333-82-0
chromium(VI) oxide

: 333995-57-6
2-[2,6-dichloro-4-(trifluoromethyl)phenyl]-5,5-difluoro-5,6-dihydrocyclopenta[c]pyrazol-4-one

Conditions

Conditions	Yield
In hexane; acetic acid; ethyl acetate	50%

: 2099-26-5
androstenediol-3,17-diacetate

: 1333-82-0
chromium(VI) oxide

: 13209-60-4
3β, 17β-diacetoxyandrost-5-ene-7-one

Conditions

Conditions	Yield
In methanol; CrO3; acetic acid	20%

: 7732-18-5
water

: 1333-82-0
chromium(VI) oxide

: 7738-94-5
chromic acid

: 1333-82-0
chromium(VI) oxide

: 103057-44-9
N-(tert-butoxycarbonyl)-3-hydroxypyrrolidine

: 85909-08-6
tert-butyl 2-oxopyrrolidine-1-carboxylate

Conditions

Conditions	Yield
With pyridine; acetic anhydride In dichloromethane; ethyl acetate

: 499790-78-2
7-benzyl-1-methyl-1,4-dihydro-9H-pyrazolo[4,3-b]quinolin-9-one

: 1333-82-0
chromium(VI) oxide

: 499792-53-9
7-benzoyl-1-methyl-1,4-dihydro-9H-pyrazolo[4,3-b]quinolin-9-one

Conditions

Conditions	Yield
In acetic anhydride

jones reagent: jones reagent

: 350231-40-2
3-[(1,2-diphenyl-1H-benzimidazol-6-yl)oxy]propan-1-ol

: 1333-82-0
chromium(VI) oxide

: 350231-41-3
3-[(1,2-diphenyl-1H-benzimidazol-6-yl)oxy]propanoic acid

Conditions

Conditions	Yield
With sulfuric acid In water; acetone

...Expand

: 173736-10-2
2-chloro-2'-methoxy-5-nitrobenzhydrol

: 1333-82-0
chromium(VI) oxide

: 173736-11-3
2-chloro-2'-methoxy-5-nitrobenzophenone

Conditions

Conditions	Yield
In methanol; dichloromethane; water; acetic acid
In methanol; dichloromethane; water; acetic acid
In methanol; dichloromethane; water; acetic acid
In methanol; dichloromethane; water; acetic acid

: 3-(4-hydroxytetrahydrofuran-3-yloxy)-4-methoxybenzonitrile

: 1333-82-0
chromium(VI) oxide

: 3-(tetrahydrofuran-4-on-3-yloxy)-4-methoxybenzonitrile

Conditions

Conditions	Yield
With pyridine; acetic anhydride In dichloromethane; water

: ethyl 3-trifluoromethyl-4-[(4-chloro-2-nitrophenyl)(hydroxy)methyl]1H-pyrazole-5-carboxylate

: 1333-82-0
chromium(VI) oxide

: ethyl 4-(4-chloro-2-nitrobenzoyl)-3-trifluoromethyl-1H-pyrazole-5-carboxylate

Conditions

Conditions	Yield
With pyridine In dichioromethane; dichloromethane	1.33 g (82%)

: 10034-88-5
sodium hydrogensulfate monohydrate

: methyl (1-hydroxymethyl-1,2,3,4-tetrahydronaphthalen-5-yl) oxyacetate

: 1333-82-0
chromium(VI) oxide

: Methyl (1-formyl-1,2,3,4-tetrahydronaphthalen-5-yl) oxyacetate

Conditions

Conditions	Yield
With pyridine In dichloromethane

...Expand

: 1333-82-0
chromium(VI) oxide

: 124243-65-8
N-<2-(2-hydroxyethoxy)ethyl>benzamide

: 142489-50-7
2-(2-benzamidoethoxy)-acetic acid

Conditions

Conditions	Yield
In sulfuric acid; acetone	2.5 g (74.7%)

: 114777-54-7
2-acetylamino-3-(2-chlorobenzoyl)-5,6-dihydro-7H-benzo[b]thiophene

: 1333-82-0
chromium(VI) oxide

: 2-acetylamino-3-(2-chlorobenzoyl)-5,6-dihydro-4H-benzo[b]thiophen-7-one

Conditions

Conditions	Yield
In water

: 5α-bromo-6β-fluoro-17α-hydroxy-16α-methyl-pregnane-3,20-dione

: 5-bromo-6β-fluoro-3β,17-dihydroxy-16-methyl-pregnan-20-one

: 1333-82-0
chromium(VI) oxide

: 67-63-0
isopropyl alcohol

: 6α-fluoro-17α-hydroxy-16α-methyl-4-pregnene-3,20-dione

Conditions

Conditions	Yield
With hydrogen bromide; sodium acetate; chromic acid In tetrahydrofuran; (2S)-N-methyl-1-phenylpropan-2-amine hydrate; sulfuric acid; water; acetic acid; acetone

...Expand

: 23202-83-7, 2592-42-9
5-benzyl-1,2-O-isopropylidene-α-D-xylofuranose

: 1333-82-0
chromium(VI) oxide

: 34311-63-2
5-O-benzyl-3-oxo-1,2-O-isopropylidene-α-D-xylofuranose

Conditions

Conditions	Yield
With pyridine In dichloromethane

: 1333-82-0
chromium(VI) oxide

: 66085-59-4
nimodipin

: 85677-93-6
Nimodipine Oxidized

Conditions

Conditions	Yield
In acetic acid
In acetic acid

: 1333-82-0
chromium(VI) oxide

: 75370-30-8
N-(6-Phenoxy-5-indanyl)-methansulfonamid

: 75360-85-9
N-[1-oxo-6-phenoxyindan-5-yl]methanesulfonamide

Conditions

Conditions	Yield
With acetic anhydride In water; acetic acid

: 81721-19-9
17β-acetoxy-3β-benzoyloxy-15β,16β-methylene-5-androstene

: 1333-82-0
chromium(VI) oxide

: 75-65-0
tert-butyl alcohol

: 81721-20-2
17β-acetoxy-3β-benzoyloxy-15β,16β-methylene-5-androsten-7-one

Conditions

Conditions	Yield
With acetic anhydride; acetic acid In tetrachloromethane

...Expand

: 119085-08-4
α-ethyl-1-(1,2,3,4-tetrahydro-1-naphthalenyl)-1H-imidazole-5-methanol

: 67-66-3
chloroform

: 1333-82-0
chromium(VI) oxide

: 1-[1-(1,2,3,4-tetrahydro-1-naphthalenyl)-1H-imidazol-5-yl]-1-propanone

Conditions

Conditions	Yield
With pyridine In methanol; dichloromethane	2.2 parts (12.3%)

...Expand

jones reagent: jones reagent

methanoate: methanoate

: 1333-82-0
chromium(VI) oxide

: 497-19-8
sodium carbonate

: 153-61-7
cephalothin

: 49769-48-4
3-formyl-7-(thien-2-ylacetamido)-2-cephem-4-carboxylic acid

Conditions

Conditions	Yield
With hydrogenchloride In pyridine; concentrated H2 SO4; water; acetic anhydride; ethyl acetate; acetone

...Expand

: 39780-02-4
(4aS)-7-methoxy-2t-methyl-2c-hydroxymethyl-1t-ethyl-(4arH.10atH)-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene

: 1333-82-0
chromium(VI) oxide

: 39780-07-9
3-methoxy-16,17-seco-estra-1,3,5(10)-trien-17-al

Conditions

Conditions	Yield
In pyridine

jones reagent: jones reagent

: 58186-18-8
2,3,5-trimethyl-6-(6'-acetoxy-1'-hydroxyhexyl)-1,4-benzoquinone

: 1333-82-0
chromium(VI) oxide

: 58186-19-9
2,3,5-trimethyl-6-(6'-acetoxy-1'-oxohexyl)-1,4-benzoquinone

Conditions

Conditions	Yield
In sulfuric acid; acetone

...Expand

: 67977-35-9
21-acetoxy-11α-hydroxy-6,16α-dimethyl-1,4,6-pregnatriene-3,20-dione

: 1333-82-0
chromium(VI) oxide

: 67977-36-0
21-acetoxy-6,16α-dimethyl-1,4,6-pregnatriene-3,11,20-trione

Conditions

Conditions	Yield
With sodium hydrogencarbonate In acetic acid

: 3-Oxa-1-(tetrahydropyran-2-yloxy)decan-9-ol

: 1333-82-0
chromium(VI) oxide

: 3-oxa-1-(tetrahydropyran-2-yloxy)decan-9-one

Conditions

Conditions	Yield
In jones reagent; sulfuric acid; water; isopropyl alcohol; acetone

Chromium trioxide Chemical Properties

Molecular Structure of Chromium trioxide (CAS NO.10043-01-3):

IUPAC Name: trioxochromium
Molecular formula: CrO₃
Molar mass: 99.9943 g/mol
H bond acceptors: 3
H bond donors: 0
Freely Rotating Bonds: 0
Polar Surface Area: 51.21 Å²
Appearance: dark red granular solid
Odor: odorless
Density: 2.70 g/cm³ (20 °C)
Melting point: 197 °C
Boiling Point: 330 °C
Flash Point: 250°C
EINECS: 215-607-8
Water Solubility Highly soluble
Product Categories: Inorganic & organic chemicals; Inorganics
Synonyms: Anidride cromica ; anidridecromica ; anidridecromica ; Chrome bronze ; chrome(trioxydede) ; chrome(trioxydede)(french)[qr] ; chrometrioxydede ; chromia(CrO₃)

Chromium trioxide Uses

Main application areas for inorganic chromium compounds industrial production. Chromium trioxide used for dyeing and printing industry, paint industry for the production of zinc chrome yellow, Cr₂O₃ organic industry for the production of low-temperature shift catalyst, the instrument of change agents, oxidation catalyst and high-pressure methanol catalyst. And also for the preservation of timber or waterproofing agent production and high purity such as electrolytic chromium metal.

Chromium trioxide Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
human	TCLo	inhalation	110ug/m³ (0.11mg/m³)		Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 22, Pg. 291, 1980.
mouse	LD50	intraperitoneal	14mg/kg (14mg/kg)		Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene. Vol. 34, Pg. 193, 1979.
mouse	LD50	intravenous	17100ug/kg (17.1mg/kg)		Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991.
mouse	LD50	oral	127mg/kg (127mg/kg)		Zhonghua Yufangyixue Zazhi. Chinese Journal of Preventive Medicine. Vol. 14, Pg. 86, 1980.
mouse	LDLo	subcutaneous	20mg/kg (20mg/kg)		Senten Ijo. Congenital Anomalies. Vol. 19, Pg. 171, 1979.
rat	LD50	intraperitoneal	58400ug/kg (58.4mg/kg)		Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991.
rat	LD50	intravenous	9260ug/kg (9.26mg/kg)		Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991.
rat	LD50	oral	80mg/kg (80mg/kg)	LUNGS, THORAX, OR RESPIRATION: CYANOSIS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Kenkyu Nenpo--Tokyo-toritsu Eisei Kenkyusho. Annual Report of Tokyo Metropolitan Research Laboratory of Public Health. Vol. 27, Pg. 119, 1976.
rat	LDLo	skin	55mg/kg (55mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: FOOD INTAKE (ANIMAL) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	National Technical Information Service. Vol. OTS0537097,

Chromium trioxide Safety Profile

Hazard Codes: Oxidizing O, Very T+, Dangerous N, Toxic T
Risk Statements: 45-46-9-24/25-26-35-42/43-48/23-50/53-62-8
R45:May cause cancer.
R46:May cause heritable genetic damage.
R9:Explosive when mixed with combustible material.
R24:Toxic in contact with skin.
R25 :Toxic if swallowed.
R26:Very toxic by inhalation.
R35:Causes severe burns.
R42/43:May cause sensitization by inhalation and skin contact.
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
R8 :Contact with combustible material may cause fire.
R62:Risk of impaired fertility.
Safety Statements: 53-45-60-61-36/37/39-28-26-22
S53:Avoid exposure - obtain special instructions before use.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S60:This material and its container must be disposed of as hazardous waste.
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S28:After contact with skin, wash immediately with plenty of soap-suds.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S22:Do not breathe dust.
RIDADR: UN 1463 5.1/PG 2
WGK Germany: 3
RTECS: GB6650000
HazardClass: 5.1
PackingGroup: II
HS Code: 28191000

Chromium trioxide Specification

Chromium trioxide (CAS NO.10043-01-3) is highly toxic, corrosive and carcinogenic. It is the main example of the environmental hazard known as "hexavalent chromium". The related chromium (III) derivatives are not particularly dangerous, thus reductants are used to destroy chromium(VI) samples. Chromium trioxide, being a powerful oxidizer, will ignite some organic materials (such as ethanol) on contact.

Product Name

Chromium(VI) trioxide

Synthetic route

Chromium trioxide Chemical Properties

Chromium trioxide Uses

Chromium trioxide Toxicity Data With Reference

Chromium trioxide Safety Profile

Chromium trioxide Specification

Related Products

Hot Products