Laurylchloride supplier | CasNO.112-52-7

Name
1-Chlorododecane
EINECS 203-981-5
CAS No. 112-52-7
Article Data61
CAS DataBase
Density 0.87 g/cm³
Solubility 0.0068 g/L (20 °C) in water
Melting Point -9.3 °C
Formula C₁₂H₂₅Cl
Boiling Point 260.4 °C at 760 mmHg
Molecular Weight 204.784
Flash Point 104.5 °C
Transport Information UN 3082 9/PG 3
Appearance Clear colorless oily liquid
Safety 24-36/37-60-61-37
Risk Codes 40-50/53-38
Molecular Structure
Hazard Symbols Xn,N,Xi
Synonyms 1-Dodecyl chloride;Dodecyl chloride;Lauryl chloride;NSC 57107;n-Dodecylchloride;n-Lauryl chloride;
PSA 0.00000
LogP 5.14610

Synthetic route

: 2-(dodecylthio)benzonitrile

A: 2634-33-5
1,2-benzisothiazolin-3-one

B: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With sulfuryl dichloride; water In chlorobenzene at 20 - 65℃; for 3h; Reagent/catalyst;	A 97.2% B 143 g
With water; chlorine In chlorobenzene at 20 - 65℃; for 3h; Reagent/catalyst;

: 2-(dodecylthio)benzonitrile

A: 2634-33-5
1,2-benzisothiazolin-3-one

B: 873-32-5
2-Chlorobenzonitrile

C: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
Stage #1: 2-(dodecylthio)benzonitrile With sulfuryl dichloride; water In chlorobenzene at 20 - 65℃; for 3h; Stage #2: With sodium hydroxide In water at 60 - 65℃; pH=9 - 10; Stage #3: With hydrogenchloride In water at 20 - 30℃; pH=3 - 4; Reagent/catalyst;	A 106 g B 97.2% C 143 g

...Expand

: 112-53-8
1-dodecyl alcohol

: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With hydrogenchloride; cetyltrimethylammonim bromide for 16h; Heating;	97%
With tetrachloromethane; 2-(2-(diphenylphosphino)ethyl)pyridine In chloroform at 35℃; for 1h; Product distribution; Mechanism; other aliphatic alcohols; var rection conditions and amounts of reagents;	97%
With pyridine; benzyltri(n-butyl)ammonium chloride; benzenesulfonyl chloride for 0.166667h; Reflux; Inert atmosphere;	96%

: C15H32NO(1+)*Cl(1-)

: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
at 60℃; for 2h;	95%
at 60℃; for 2h;

: 51323-71-8
dodecyl mesylate

: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With lithium chloride In tetrahydrofuran for 24h; Inert atmosphere; Reflux;	94%

: 24460-74-0
n-dodecyl chloroformate

: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With N,N-dimethyl-formamide at 26 - 32℃;	91%

: 4292-19-7
1-Iodododecane

A: 1851-93-0
1-phenyl-1-dodecanol

B: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With chromium dichloride; benzaldehyde In N,N-dimethyl-formamide at 30℃; for 16h;	A 7% B 88%

: 4292-19-7
1-Iodododecane

: 100-52-7
benzaldehyde

A: 1851-93-0
1-phenyl-1-dodecanol

B: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With chromium dichloride In N,N-dimethyl-formamide at 30℃; for 16h;	A 7% B 88%

...Expand

: 112-53-8
1-dodecyl alcohol

: 98-88-4
benzoyl chloride

A: 2915-72-2
dodecyl benzoate

B: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With 2,3-diethyl-2-cyclopropen-1-one In tert-butyl methyl ether at 40℃; for 6h; Catalytic behavior; Reagent/catalyst; Temperature;	A n/a B 87%
With N,N-dimethyl-formamide In 1,4-dioxane at 20℃; for 20h;
With 1,1'-sulfinylbisbenzene In acetonitrile at 40℃; for 20h; Catalytic behavior; Temperature; Sealed tube;

...Expand

: 2386-53-0
sodium dodecyl sulfate

: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With thionyl chloride In N,N-dimethyl-formamide at 100℃; for 1h;	81%

: 334-68-9
1-fluorododecane

A: 143-15-7
1-dodecylbromide

B: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With bis(cyclopentadienyl)titanium dichloride; triethylaluminum; 1,2-dibromomethane In hexane at 20℃; for 24h; Solvent;	A 77% B 22%

: 112-53-8
1-dodecyl alcohol

: 3282-30-2
pivaloyl chloride

A: dodecyl pivalate

B: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With diphenylcyclopropenone In tert-butyl methyl ether at 20℃; for 20h;	A n/a B 72%

...Expand

: 3760-54-1
1-pyrrolidinecarboxaldehyde

: 112-53-8
1-dodecyl alcohol

A: 28303-42-6
1-dodecanyl formate

B: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With 1,3,5-trichloro-2,4,6-triazine In acetone at 80℃; for 21h; Solvent; Temperature; Sealed tube; Green chemistry;	A 15 %Spectr. B 72%
With benzoyl chloride In acetonitrile at 20℃; for 4h;

...Expand

: 151259-26-6
C19H34N2O2S

A: 98-59-9
p-toluenesulfonyl chloride

B: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With N-chloro-succinimide In tetrahydrofuran for 16h; Ambient temperature; Irradiation;	A n/a B 68%

: 112-53-8
1-dodecyl alcohol

: 141-78-6
ethyl acetate

A: 112-66-3
lauryl acetate

B: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With 1-pyrrolidinecarboxaldehyde; 1,3,5-trichloro-2,4,6-triazine at 80℃; for 5h; Sealed tube; Green chemistry;	A 27 %Spectr. B 61%

...Expand

: 112-53-8
1-dodecyl alcohol

: 75-36-5
acetyl chloride

A: 112-66-3
lauryl acetate

B: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With diphenylcyclopropenone In tert-butyl methyl ether at 20℃; for 20h;	A n/a B 46%

...Expand

: 112-40-3
dodecane

: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
at 240 - 280℃; thermische Chlorierung in der Gasphase;

: 112-40-3
dodecane

A: 2350-11-0
2-chlorododecane

B: 2350-13-2
4-chloro-dodecane

C: 2350-12-1
3-chlorododecane

D: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
Chlorieren;mit UV-Licht;Produkt5-6:5-Chlor-dodecan,6-Chlor-dodecan;analog verlaeuft die Nitrierung mit Salpetersaeure-Daempfen bei 170grad.Irradiation;

...Expand

: 74-85-1
ethene

: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With hydrogenchloride at 50 - 200℃; unter Druck;

: 10147-40-7
1-Dodecanesulfonyl chloride

: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With xylene

: 112-40-3
dodecane

A: 2350-11-0
2-chlorododecane

B: 3922-28-9
1,12-dichlorododecane

C: 75121-23-2
1,2-dichlorododecane

D: 2350-12-1
3-chlorododecane

E: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With zeolite LZ 105; chlorine Product distribution; Mechanism; Irradiation; other 1-substituted alkanes;

...Expand

: 102402-78-8
C18H30Cl2Se

: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With chloride Ambient temperature; Yield given;

: 75250-43-0
dichloro(dodecyl)phenyltellurium

A: 32294-60-3
diphenyl ditelluride

B: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With sodium chloride In N,N-dimethyl-formamide at 100℃; Yield given;

: 112-40-3
dodecane

A: 3922-28-9
1,12-dichlorododecane

B: 75121-23-2
1,2-dichlorododecane

C: 62017-17-8
1,1-dichlorododecane

D: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With KLZ-105 zeolite; chlorine Irradiation;
With LiLZ-105 zeolite; chlorine Irradiation;
With CsLZ-105 zeolite; chlorine Irradiation;

...Expand

: 112-40-3
dodecane

A: 3922-28-9
1,12-dichlorododecane

B: 75121-23-2
1,2-dichlorododecane

C: 62017-17-8
1,1-dichlorododecane

D: 112-52-7
1-chlorododecane

E: 1,3-dichlorododecane

Conditions

Conditions	Yield
With LiLZ-105 zeolite; chlorine at 24 - 73℃; Product distribution; Mechanism; Irradiation; other LZ-105 zeolites;

...Expand

: 112-55-0
1-dodecylthiol

: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
With N-chloro-succinimide; triphenylphosphine In dichloromethane at 20℃; for 0.75h;	75 % Spectr.
Multi-step reaction with 2 steps 1.1: tetrabutylammomium bromide; sodium hydroxide / chlorobenzene; water / 4 h / 65 - 70 °C / Inert atmosphere 2.1: water; sulfuryl dichloride / chlorobenzene / 3 h / 20 - 65 °C 2.2: 60 - 65 °C / pH 9 - 10 2.3: 20 - 30 °C / pH 3 - 4 View Scheme

: 124-22-1
n-Dodecylamine

2) HCl: 2) HCl

: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 2: 1.) base, 2.) O-(2,4-dinitrophenyl)hydroxylamine 3: 68 percent / NCS / tetrahydrofuran / 16 h / Ambient temperature; Irradiation View Scheme

: 1635-09-2
N-dodecyl-4-methylbenzenesulfonamide

: 112-52-7
1-chlorododecane

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 1.) base, 2.) O-(2,4-dinitrophenyl)hydroxylamine 2: 68 percent / NCS / tetrahydrofuran / 16 h / Ambient temperature; Irradiation View Scheme

: 92430-96-1
p-N,N-dimethylamino benzamidopropyldimethylamine

: 112-52-7
1-chlorododecane

: 849699-52-1
p-N,N-dimethylaminobenzamidopropyl(dimethyl)(lauryl)ammonium chloride

Conditions

Conditions	Yield
at 110℃; for 20h;	99.9%

: 104040-44-0
(p-methoxycinnamidopropyl)dimethylamine

: 112-52-7
1-chlorododecane

: 104024-25-1
p-methoxy cinnamidopropyldimethyllauryl ammonium chloride

Conditions

Conditions	Yield
at 110℃; for 20h;	99.9%

: 112-52-7
1-chlorododecane

: 111757-80-3
(-)-(2S)-trifluoromethanesulfonyloxy-propionic acid tert-butyl ester

: 1059044-04-0
(+)-(2S)-methyl-tetradecanoic acid tert-butyl ester

Conditions

Conditions	Yield
Stage #1: 1-chlorododecane With magnesium In tetrahydrofuran Inert atmosphere; Stage #2: (-)-(2S)-trifluoromethanesulfonyloxy-propionic acid tert-butyl ester With zinc(II) chloride In tetrahydrofuran at 0℃; for 3h; Inert atmosphere; optical yield given as %ee; enantiospecific reaction;	99%

: 120-94-5
1-Methylpyrrolidine

: 112-52-7
1-chlorododecane

: 114569-86-7
1-dodecyl-1-methylpyrrolidinium chloride

Conditions

Conditions	Yield
for 0.333333h; Microwave irradiation;	98%
at 70 - 100℃;
In toluene at 114.84℃; for 24h; Inert atmosphere;

: 111-40-0
1,5-diamino-3-azapentane

: 112-52-7
1-chlorododecane

: 3700-59-2
2-[2-(n-dodecylamino)ethylamino]ethylamine

Conditions

Conditions	Yield
at 160℃; for 1h;	97.6%

: 107-15-3
ethylenediamine

: 112-52-7
1-chlorododecane

: 35902-68-2
N-dodecyl-ethane-1,2-diamine

Conditions

Conditions	Yield
at 110 - 120℃; for 1h;	97%
In ethanol for 24h; Reflux;	82%
In ethanol for 24h; Heating;	45%

: 616-47-7
1-methyl-1H-imidazole

: 112-52-7
1-chlorododecane

: 1-dodecyl-3-methylimidazol-1-ium chloride

Conditions

Conditions	Yield
at 100℃; for 72h; Inert atmosphere;	97%
at 160℃; for 0.25h; Microwave irradiation; Neat (no solvent);	92%
for 0.05h; Microwave irradiation; neat (no solvent);	92%

: 1379610-52-2
4,4,5,5‐tetramethyl‐2‐[5‐phenyl‐1‐(4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolan‐2‐yl)propyl]‐1,3,2‐dioxaborolane

: 112-52-7
1-chlorododecane

: 4,4,5,5-tetramethyl-2-(1-phenylpentadecan-3-yl)-1,3,2-dioxaborolane

Conditions

Conditions	Yield
With potassium tert-butylate In toluene at 20℃; for 3h; Sealed tube;	97%

: 112-52-7
1-chlorododecane

: 59227-89-3
Azone

Conditions

Conditions	Yield
	95.2%

: 112-52-7
1-chlorododecane

: 13733-78-3
dodecyl azide

Conditions

Conditions	Yield
With trimethylsilylazide; tetrabutyl ammonium fluoride In tetrahydrofuran at 50℃; for 28h;	95%

: 7677-24-9
trimethylsilyl cyanide

: 112-52-7
1-chlorododecane

: 629-60-7
tridecanenitrile

Conditions

Conditions	Yield
With tetrabutyl ammonium fluoride In acetonitrile at 82℃; for 3h; Product distribution; other temperature, reaction time;	95%

: 2840-28-0
3-amino-4-chloro-benzoic acid

: 112-52-7
1-chlorododecane

: 6195-20-6
n-dodecyl 3-amino-4-chlorobenzoate

Conditions

Conditions	Yield
With potassium carbonate In methanol; water; dimethyl sulfoxide; ethyl acetate	95%

: 15871-54-2
1,3,8-triaza-7,7,9,9-tetramethyl-spiro[4.5]decane-2,4-dione

: 112-52-7
1-chlorododecane

: 67778-10-3
3-dodecyl-7,7,9,9-tetramethyl-1,3,8-triazaspiro[4,5]decane-2,4-dione

Conditions

Conditions	Yield
With potassium hydroxide; tetrabutyl ammonium fluoride In water; dimethyl sulfoxide; xylene for 5h; Product distribution / selectivity; Heating / reflux;	94.2%
With sodium hydroxide; tetrabutyl ammonium fluoride In water; dimethyl sulfoxide; xylene for 5h; Product distribution / selectivity; Heating / reflux;	92.3%
With potassium hydroxide; tetrabutyl-ammonium chloride In water; dimethyl sulfoxide; xylene for 5h; Product distribution / selectivity; Heating / reflux;	88.3%

: 149-30-4
2-Mercaptobenzothiazole

: 112-52-7
1-chlorododecane

: 95487-21-1
2-hexadecylsulfanyl-benzothiazole

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide for 1h; Ambient temperature;	94%

: 57-14-7
1,1-dimethylhydrazine

: 112-52-7
1-chlorododecane

: 1,1-dimethyl-1-dodecylhydrazinium chloride

Conditions

Conditions	Yield
at 60℃; for 11h;	94%
at 80 - 85℃; for 5h; Alkylation;

: 109-76-2
Trimethylenediamine

: 112-52-7
1-chlorododecane

: 5538-95-4
N-(1-dodecyl)-1,3-propanediamine

Conditions

Conditions	Yield
In ethanol for 24h; Reflux;	94%
In ethanol for 24h; Heating;	53%
In ethanol for 24h; Reflux;

: 7,7,9,9-tetramethyl-1,3,8-triazaspiro[4,5]decane-2,4-dione potassium salt

: 112-52-7
1-chlorododecane

: 67778-10-3
3-dodecyl-7,7,9,9-tetramethyl-1,3,8-triazaspiro[4,5]decane-2,4-dione

Conditions

Conditions	Yield
With tetrabutyl ammonium fluoride In water; dimethyl sulfoxide; xylene for 5h; Product distribution / selectivity; Heating / reflux;	94%
With tetrabutyl-ammonium chloride In water; dimethyl sulfoxide; xylene for 5h; Product distribution / selectivity; Heating / reflux;	90%
With tetrabutyl-ammonium chloride In dimethyl sulfoxide; xylene for 5h; Product distribution / selectivity; Heating / reflux;	85.2%
In water; dimethyl sulfoxide; xylene for 5h; Product distribution / selectivity; Heating / reflux;	46.3%
In dimethyl sulfoxide; xylene for 5h; Product distribution / selectivity; Heating / reflux;	24%

: 108-98-5
thiophenol

: 112-52-7
1-chlorododecane

: 56056-49-6
(n-dodecylthio)benzene

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide for 1h; Ambient temperature;	93%

: 998-40-3
tributylphosphine

: 112-52-7
1-chlorododecane

: dodecyl tributyl phosphonium chloride

Conditions

Conditions	Yield
In toluene at 145℃; for 16h;	93%

: 112-52-7
1-chlorododecane

: 4484-72-4
n-dodecyltrichlorosilane

Conditions

Conditions	Yield
With trichlorosilane; tetra-n-butylphosphonium chloride at 170℃; for 4h;	92%

: 4731-53-7
TOP

: 112-52-7
1-chlorododecane

: 1352944-95-6
trioctyl(dodecyl)phosphonium chloride

Conditions

Conditions	Yield
at 145℃; for 16h; Inert atmosphere; neat (no solvent);	92%

: N,N-bis(2-sulfonic acid ethyl)amine

: 112-52-7
1-chlorododecane

: 78107-98-9
N,N-bis(2-sulfoethyl)-1-dodecanamine disodium salt

Conditions

Conditions	Yield
With sodium hydroxide In water; acetone at 50℃; for 1h; pH=9 - 10;	91.5%

: 112-52-7
1-chlorododecane

: 112-40-3
dodecane

Conditions

Conditions	Yield
With samarium diiodide In tetrahydrofuran at 40℃; Reduction; Irradiation;	91%
With samarium diiodide In tetrahydrofuran at 40℃; for 4h; Irradiation;	91%
With zirconocene dichloride; triethyl borane In tetrahydrofuran; hexane at 25℃; for 15h;	73%

: 1072-63-5
1-vinylimidazole

: 112-52-7
1-chlorododecane

: 1-vinyl-3-dodecylimidazolium chloride

Conditions

Conditions	Yield
In toluene at 100℃; for 48h; Inert atmosphere;	91%

Laurylchloride Specification

The IUPAC name of Dodecane, 1-chloro- is Laurylchloride. With the CAS registry number 112-52-7, it is also named as Lauryl chloride. The product's categories are alkyl chlorides; monofunctional & alpha,omega-bifunctional alkanes; monofunctional alkanes. It is clear colorless oily liquid which is insoluble in water, and soluble in benzene and ethanol. In addition, this chemical is combustible and may be incompatible with strong oxidizing and reducing agents. And it is also incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

The other characteristics of this product can be summarized as: (1)ACD/LogP: 6.81; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): 6.81; (4)ACD/LogD (pH 7.4): 6.81; (5)ACD/BCF (pH 5.5): 88850.8; (6)ACD/BCF (pH 7.4): 88850.8; (7)ACD/KOC (pH 5.5): 121291.77; (8)ACD/KOC (pH 7.4): 121291.77; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 10; (12)Index of Refraction: 1.438; (13)Molar Refractivity: 62.49 cm³; (14)Molar Volume: 238 cm³; (15)Polarizability: 24.77×10^-24cm³; (16)Surface Tension: 28.1 dyne/cm; (17)Enthalpy of Vaporization: 47.8 kJ/mol; (18)Vapour Pressure: 0.0199 mmHg at 25°C; (19)Rotatable Bond Count: 10; (20)Exact Mass: 204.164479; (21)MonoIsotopic Mass: 204.164479; (22)Heavy Atom Count: 13; (23)Complexity: 81.2.

Preparation of Dodecane, 1-chloro-: It can be obtained by dodecan-1-ol with PPh₃ and Me₂SeCl₂ in solvent benzene. The reaction time is 4.0 hours. The yield is 80%.

Uses of Dodecane, 1-chloro-: is used as Surfactants, plasticizers, organic synthesis intermediate. It can react with ethane-1,2-diamine to get N-dodecyl-ethylenediamine. This reaction needs reagent ethanol at temperature of 110 - 120 °C. The reaction time is 1 hours. The yield is 97%.

When you are using this chemical, please be cautious about it as the following:
It is irritating to skin, so people should avoid contact with skin. And it is very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. If you want to contact this product, you must wear suitable protective clothing and gloves. This material and its container must be disposed of as hazardous waste. Avoid release to the environment. Refer to special instructions / safety data sheets.

People can use the following data to convert to the molecule structure.
1. SMILES: ClCCCCCCCCCCCC;
2. InChI: InChI=1/C12H25Cl/c1-2-3-4-5-6-7-8-9-10-11-12-13/h2-12H2,1H3.

Product Name

1-Chlorododecane

Synthetic route

Laurylchloride Specification

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