Succinonitrile supplier | CasNO.110-61-2

Name
1,4-Butanedinitrile
EINECS 203-783-9
CAS No. 110-61-2
Article Data79
CAS DataBase
Density 0.984 g/cm³
Solubility Slightly soluble in water
Melting Point 50-54 °C(lit.)
Formula C₄H₄N₂
Boiling Point 268.5 °C at 760 mmHg
Molecular Weight 80.0892
Flash Point 141.1 °C
Transport Information
Appearance almost white to brown crystalline solid
Safety 26-36/37-45-36/37/39-22
Risk Codes 22-36/37/38-36/38-20/21/22
Molecular Structure
Hazard Symbols Xn
Synonyms Deprelin;Dician;Dinile;Disuxyl;Ethane, 1,2-dicyano-;Ethylene cyanide;Ethylene dicyanide;Evanex;NSC 4852;Succinic acid dinitrile;Succinic acidnitrile;Succinic dinitrile;Succinil;Succinodinitrile;Suxil;sym-Dicyanoethane;Succinonitrile(8CI);1,2-Dicyanoethane;1,2-Ethanedicarbonitrile;1,4-Butanedinitrile;
PSA 47.58000
LogP 0.81376

Synthetic route

: 7677-24-9
trimethylsilyl cyanide

: 5535-48-8
PVS

: 110-61-2
butanedinitrile

Conditions

Conditions	Yield
With tetrabutyl ammonium fluoride In tetrahydrofuran; acetonitrile at 20℃; for 20h; Michael Addition; Inert atmosphere;	98%

: 542-76-7
3-Chloropropionitrile

: 75-86-5
2-hydroxy-2-methylpropanenitrile

: 110-61-2
butanedinitrile

Conditions

Conditions	Yield
Stage #1: 2-hydroxy-2-methylpropanenitrile With lithium hydroxide monohydrate In tetrahydrofuran at 50℃; for 1h; Stage #2: 3-Chloropropionitrile In tetrahydrofuran	98%

: WH2(η-cyclopentadienyl)2

: 764-42-1
1,2-Dicyanoethylene

A: 110-61-2
butanedinitrile

B: (C5H5)2W(CNCHCHCN)

Conditions

Conditions	Yield
In toluene Irradiation (UV/VIS); (Ar); addn. of fumaronitrile to soln. of W-compd. in toluene portionwise, irradn. (500 W Hg-lamp, >550 nm, 62 h), pptn.; decantation of supernatant, washing (toluene), drying in vac.; elem. anal., detn. of isomeric ratio of CNCH=CHCN ligand fumaronitrile/maleonitrile 3:2 by (1)H-NMR spectroscopy;	A 92% B 38%

...Expand

: 33695-47-5
(phenylselenenyl)acetonitrile

A: 110-61-2
butanedinitrile

B: 1666-13-3
diphenyl diselenide

Conditions

Conditions	Yield
at 600℃; under 20 Torr; for 0.0333333h;	A 87% B 90%

: 764-42-1
butenedinitrile

: 110-61-2
butanedinitrile

Conditions

Conditions	Yield
With hydrogen sulfide	90%
With hydrogen at 20℃; under 750.075 Torr; for 0.0833333h; Inert atmosphere; Neat (no solvent);	96 %Chromat.

: 107-13-1
acrylonitrile

: 75-86-5
2-hydroxy-2-methylpropanenitrile

: 110-61-2
butanedinitrile

Conditions

Conditions	Yield
With Cp*2Sm(THF)2 In toluene for 15h; Product distribution; Ambient temperature; other reagent;	89%
With sodium hydroxide

: potassium cyanide

: 107-06-2
1,2-dichloro-ethane

: 72537-17-8
2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

A: 110-61-2
butanedinitrile

B: 80194-70-3
3-chloro-2-cyano-5-(trifluoromethyl)pyridine

Conditions

Conditions	Yield
With dmap In water at 75 - 78℃; for 12h; Reagent/catalyst; Temperature;	A 81.8% B 86.7%

...Expand

: 68897-45-0
N,N,N',N',N'',N''-Hexamethylguanidiniumcyanid

: 106-93-4
ethylene dibromide

A: 110-61-2
butanedinitrile

B: 6926-43-8
1,1,2,2,3,3-Hexamethylguanidiniumbromid

Conditions

Conditions	Yield
In dichloromethane at 20℃; for 2h;	A 85% B n/a

...Expand

: 110-14-5
butanediamide

: 110-61-2
butanedinitrile

Conditions

Conditions	Yield
With lead acetate In dichloromethane for 12h; Reflux;	85%
With sieve-supported lead catalyst at 200℃; under 2250.23 Torr; for 0.3h;

: 3515-93-3
4-oxobutanenitrile

: 110-61-2
butanedinitrile

Conditions

Conditions	Yield
With HCl·DMPU; hydroxylamine hydrochloride In acetonitrile at 60℃;	84%

: 110-60-1
1,4-diaminobutane

: 110-61-2
butanedinitrile

Conditions

Conditions	Yield
With ammonium hydroxide; oxygen In tert-Amyl alcohol at 110℃; under 2250.23 Torr; for 15h; Autoclave; Green chemistry;	82%
With [Ru(p-cymene)(pzH-NP)(Cl)]Cl; potassium tert-butylate In toluene at 70℃; for 24h; Schlenk technique; Inert atmosphere;	58 %Chromat.

: 105041-08-5
2-cyanoacetyl bromide

: 619-72-7
4-nitrobenzonitrile

: 110-61-2
butanedinitrile

Conditions

Conditions	Yield
With copper(l) chloride In cyclohexane at 55 - 135℃; under 75.0075 Torr; for 16.1667h; Temperature; Pressure;	82%

: 773837-37-9
sodium cyanide

: 106-93-4
ethylene dibromide

: 110-61-2
butanedinitrile

Conditions

Conditions	Yield
In ethanol; water for 24h; Reflux;	72%

: 286-75-9, 19740-81-9, 57378-35-5
1,2:5,6-diepoxycyclooctane

: 110-61-2
butanedinitrile

Conditions

Conditions	Yield
With ammonia; iodine In water; acetonitrile at 70℃;	71%

: 110-15-6
succinic acid

: 110-61-2
butanedinitrile

Conditions

Conditions	Yield
With ammonia; silicon monophosphate In water at 420℃; for 5h; Product distribution / selectivity;	70%

: potassium cyanide

: 107-06-2
1,2-dichloro-ethane

: 110-61-2
butanedinitrile

Conditions

Conditions	Yield
In ethanol; water for 24h; Reflux;	69%

: 76-05-1
trifluoroacetic acid

: 764-42-1
1,2-Dicyanoethylene

A: 110-61-2
butanedinitrile

B: 90220-86-3
1,2,3,4-tetracyanobutane

C: 127085-57-8
2-(trifluoromethyl)succinonitrile

Conditions

Conditions	Yield
With sodium hydroxide In water; acetonitrile at 50℃; Product distribution; Mechanism; other temperatures, various electrode distances;	A 7% B 8% C 65%
With sodium hydroxide In water; acetonitrile at 50℃; Mechanism; Product distribution; electrolytical trifluoromethylation, Pt electrodes, variation of temperature and cell dimensions;	A 7% B 8% C 65%
With sodium hydroxide In water; acetonitrile at 50℃; electrolytical trifluoromethylation, Pt electrodes, undivided cell;	A 7% B 8% C 65%
With sodium hydroxide In water; acetonitrile at 50℃;	A 7% B 8% C 65%

...Expand

: 764-42-1
1,2-Dicyanoethylene

A: 110-61-2
butanedinitrile

B: 90220-86-3
1,2,3,4-tetracyanobutane

C: 127085-57-8
2-(trifluoromethyl)succinonitrile

Conditions

Conditions	Yield
With sodium hydroxide In water; acetonitrile; trifluoroacetic acid at 50℃;	A 7% B 8% C 65%

...Expand

: 764-42-1
1,2-Dicyanoethylene

: 110-61-2
butanedinitrile

Conditions

Conditions	Yield
With rongalite In water for 3h; Heating;	49%
With diethyl ether; copper at 140℃; Hydrogenation.unter Druck;

: 106-99-0
buta-1,3-diene

: 110-61-2
butanedinitrile

Conditions

Conditions	Yield
With ammonia; oxygen; Catalyst I at 560℃; Product distribution / selectivity;	36%
With ammonia; oxygen; Catalyst A at 560℃; Product distribution / selectivity;	31%

: N-Ethylidenasparaginsaeuredinitril

A: 504-24-5
4-aminopyridine

B: 110-61-2
butanedinitrile

C: 2-Eth-(E)-ylideneamino-acrylonitrile

D: (Z)-2-Methyl-3-azahex-4-endinitril

E: (E)-2-Methyl-3-azahex-4-endinitril

Conditions

Conditions	Yield
With 4 A molecular sieve at 500℃; under 0.1 Torr; Product distribution; flash vaccum pyrolysis;	A 26.1% B n/a C n/a D n/a E n/a

...Expand

: N-Ethylidenasparaginsaeuredinitril

A: 504-24-5
4-aminopyridine

B: 110-61-2
butanedinitrile

C: (Z)-2-Methyl-3-azahex-4-endinitril

D: (E)-2-Methyl-3-azahex-4-endinitril

Conditions

Conditions	Yield
With 4 A molecular sieve at 500℃; under 0.1 Torr; Yield given. Further byproducts given. Yields of byproduct given. Title compound not separated from byproducts;	A 26.1% B n/a C n/a D n/a

...Expand

: 107-14-2
chloroacetonitrile

: 108-88-3
toluene

A: 110-61-2
butanedinitrile

B: 2947-60-6
3-methylbenzyl cyanide

C: 2947-61-7
(4-methylphenyl)acetonitrile

D: 103-29-7
1,1'-(1,2-ethanediyl)bisbenzene

E: 645-59-0
dihydrocinnamonitrile

F: 22364-68-7
2-tolylmethylnitrile

Conditions

Conditions	Yield
In acetonitrile Product distribution; Mechanism; Irradiation; different concentration ratios;	A 0.7% B n/a C n/a D 2.1% E 6.4% F n/a
In acetonitrile for 22h; Kinetics; Product distribution; Mechanism; Irradiation;	A 0.7% B n/a C n/a D 2.1% E 6.4% F n/a

...Expand

: 2372-21-6
OO-tert-butyl O-isopropyl monoperoxycarbonate

: 107-14-2
chloroacetonitrile

: 108-88-3
toluene

A: 110-61-2
butanedinitrile

B: 100-44-7
benzyl chloride

C: 103-29-7
1,1'-(1,2-ethanediyl)bisbenzene

Conditions

Conditions	Yield
In acetonitrile at 80℃; for 168h; Product distribution;	A 1.2% B 5.7% C 3.6%

...Expand

: 33898-53-2
2-cyanoaziridine

A: 110-61-2
butanedinitrile

B: 19866-98-9
(E/Z)-3-aminoprop-2-enenitrile

C: 628-87-5
iminodiacetonitrile

Conditions

Conditions	Yield
With quartz at 630℃; under 0.1 Torr; Product distribution; flash vaccum pyrolysis;	A 3% B 4.8% C 2%
With quartz at 630℃; under 0.1 Torr;	A 3% B 4.8% C 2%

...Expand

: 16066-38-9
di-n-propyl peroxydicarbonate

: 107-14-2
chloroacetonitrile

: 108-88-3
toluene

A: 110-61-2
butanedinitrile

B: 103-29-7
1,1'-(1,2-ethanediyl)bisbenzene

C: 645-59-0
dihydrocinnamonitrile

Conditions

Conditions	Yield
In acetonitrile at 60℃; for 24h; Product distribution;	A 0.2% B 1% C 3.4%

...Expand

: 107-14-2
chloroacetonitrile

: 100-66-3
methoxybenzene

A: 110-61-2
butanedinitrile

B: 19924-43-7
3-methoxyphenylacetonitrile

C: 7035-03-2
2-methoxy-benzeneacetonitrile

D: 104-47-2
p-methoxybenzylnitrile

Conditions

Conditions	Yield
In acetonitrile Product distribution; Mechanism; Irradiation; different concentration ratios;	A 2.3% B n/a C n/a D n/a
In acetonitrile for 22h; Kinetics; Product distribution; Mechanism; Irradiation;	A 2.3% B n/a C n/a D n/a

...Expand

: 107-14-2
chloroacetonitrile

: 71-43-2
benzene

A: 110-61-2
butanedinitrile

B: 140-29-4
phenylacetonitrile

Conditions

Conditions	Yield
In acetonitrile for 22h; Irradiation;	A 0.5% B 1.9%
In acetonitrile Product distribution; Mechanism; Irradiation; different times of photolysis; different concentration ratios;	A 0.5% B 1.9%

...Expand

: 462-06-6
fluorobenzene

: 107-14-2
chloroacetonitrile

A: 110-61-2
butanedinitrile

B: 501-00-8
3-fluorophenylacetonitrile

C: 326-62-5
2-fluorophenyl acetonitrile

D: 459-22-3
4-fluorophenylacetonitrile

Conditions

Conditions	Yield
In acetonitrile Product distribution; Mechanism; Irradiation; different concentration ratios;	A 0.5% B n/a C n/a D n/a
In acetonitrile for 22h; Kinetics; Product distribution; Mechanism; Irradiation;

...Expand

: 110-61-2
butanedinitrile

: 252959-29-8
C18H19NO

: C40H36N2O2

Conditions

Conditions	Yield
With zinc(II) chloride In chlorobenzene for 133h; Condensation; Heating;	100%

: 110-61-2
butanedinitrile

: 110-14-5
butanediamide

Conditions

Conditions	Yield
With manganese(IV) oxide; water In isopropyl alcohol at 100℃; under 5171.62 Torr; for 0.5h;	99%
With aluminum oxide; methanesulfonic acid at 120℃; for 0.25h;	85%
Stage #1: butanedinitrile With acetamide; acetic acid at 50℃; under 760.051 Torr; for 0.5h; Stage #2: With tetrakis(acetonitrile)palladium(II) tetrafluoroborate at 50℃; under 1 - 3 Torr; for 2h;	61%

: 110-61-2
butanedinitrile

: 16051-87-9
3-cyanopropanoic acid

Conditions

Conditions	Yield
enzyme from Synechocystis sp. PCC 6803 In phosphate buffer at 30℃; for 12h;	99%
With Bradyrhizobium japonicum strain USDA110 nitrilase bll6402 In phosphate buffer at 30℃; for 24h; pH=7.2;	97%
With water; nitrile hydratase SP361 at 30℃; for 71h; in potassium phosphate buffer (pH = 7);	65%

: 110-61-2
butanedinitrile

: 64-17-5
ethanol

: 52426-61-6
succinodiimidic acid diethyl ester; dihydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In benzene at 0 - 5℃; for 1.5h;	98%

: 110-61-2
butanedinitrile

: 109-94-4
formic acid ethyl ester

: 89283-73-8
(E,Z)-2-formylsuccinonitrile potassium salt

Conditions

Conditions	Yield
With potassium tert-butylate In toluene; tert-butyl alcohol at 20℃; for 2h; Cooling with ice;	98%
With potassium tert-butylate In toluene; tert-butyl alcohol at 5℃; for 6h;	96%
With potassium tert-butylate In toluene; tert-butyl alcohol at 3 - 10℃; for 2.5h;

: 110-61-2
butanedinitrile

: 109-76-2
Trimethylenediamine

: 78706-92-0
1,2-bis(1,4,5,6-tetrahydropyrimidin-2-yl)ethane

Conditions

Conditions	Yield
With Lawessons reagent In toluene at 90℃; for 10h; thio-Pinner's reaction;	98%

: 110-61-2
butanedinitrile

: 107-15-3
ethylenediamine

: 29957-52-6
1,2-bis(4,5-dihydro-1H-imidazol-2-yl)ethane

Conditions

Conditions	Yield
With diphosphorus pentasulfide In toluene at 90℃; for 10h; thio-Pinner's reaction;	97%

: 110-61-2
butanedinitrile

: 130777-67-2
((1,2-bis(diisopropylphosphino)ethane)NiH)2

: 1177406-40-4
[(1,2-bis(diisopropylphosphano)ethane)Ni(η2-N,C-(CH2)2-CN)]

Conditions

Conditions	Yield
In tetrahydrofuran byproducts: H2; under Ar, in glove box; ((dippe)NiH)2 dissolved in dry THF at room temp., 2 equiv. of dinitrile added, mixt. stirred for 15 min; evapd. under vac., residue dried under vac. for 6 h;	96%

: 110-61-2
butanedinitrile

: 59543-92-9
1,3-diaminopropane mono-p-toluenesulfonate

: 78707-11-6
C24H30N4O4S2

Conditions

Conditions	Yield
at 140℃; for 0.5h;	95%

: 110-61-2
butanedinitrile

: dichlorosuccinonitrile

Conditions

Conditions	Yield
With manganese(IV) oxide; sulfuric acid; chlorine; sodium chloride In chlorobenzene Heating;	95%

: 110-61-2
butanedinitrile

: 141-78-6
ethyl acetate

: 1510825-77-0
sodium 3,4-dicyanobut-2-en-2-olate

Conditions

Conditions	Yield
With i-Amyl alcohol; sodium hydride In toluene; mineral oil at 20℃;	95%

: 110-61-2
butanedinitrile

: 333-93-7
putrescine dihydrochloride

Conditions

Conditions	Yield
Stage #1: butanedinitrile With cobalt pivalate; 1,1,3,3-Tetramethyldisiloxane; tert-butylisonitrile at 80℃; for 24h; Stage #2: With hydrogenchloride In diethyl ether at 20℃; for 0.5h;	95%

: 110-61-2
butanedinitrile

: C6H4BF4*K(1+)

: 2,5-bis(4-fluorophenyl)-1H-pyrrole

Conditions

Conditions	Yield
With [2,2]bipyridinyl; ammonium trifluoroacetate; palladium(II) trifluoroacetate; trifluoroacetic acid In tetrahydrofuran; water at 80℃; for 30h; Solvent; Reagent/catalyst; Inert atmosphere;	93.6%

: 110-61-2
butanedinitrile

: 1765-93-1
4-fluoroboronic acid

: 2,5-bis(4-fluorophenyl)-1H-pyrrole

Conditions

Conditions	Yield
With [2,2]bipyridinyl; palladium(II) trifluoroacetate; 2,2,2-trifluoroacetic acid ammonia; trifluoroacetic acid In tetrahydrofuran; water at 80℃; for 48h; Schlenk technique;	93%

: 110-61-2
butanedinitrile

: potassium phenyltrifluoroborate

: 838-40-4
2,5-diphenyl-1H-pyrrole

Conditions

Conditions	Yield
With [2,2]bipyridinyl; ammonium trifluoroacetate; palladium(II) trifluoroacetate; trifluoroacetic acid In tetrahydrofuran; water at 70℃; for 40h; Solvent; Reagent/catalyst; Inert atmosphere;	92.7%

: 110-61-2
butanedinitrile

A: 616-45-5
2-pyrrolidinon

B acrylobutyronitril: acrylobutyronitril

C: 110-60-1
1,4-diaminobutane

Conditions

Conditions	Yield
With rubidium hydroxide; hydrogen; ethylenediamine; RaNi catalyst doped with Fe and Cr, slurry in water In water at 80℃; under 525053 Torr; Product distribution / selectivity;	A 3% B 1% C 92%
With cesium hydroxide; hydrogen; ethylenediamine; RaNi catalyst doped with Fe and Cr, slurry in water In water at 80℃; under 525053 Torr; Product distribution / selectivity;	A 3% B 5% C 90%
With sodium hydroxide; hydrogen; ethylenediamine; RaNi catalyst doped with Fe and Cr, slurry in water In water at 80℃; under 525053 Torr; Product distribution / selectivity;	A 4% B 5% C 85%

...Expand

: 110-61-2
butanedinitrile

: 98-80-6
phenylboronic acid

: 5343-98-6
4-oxo-4-phenylbutanenitrile

Conditions

Conditions	Yield
With [2,2]bipyridinyl; palladium(II) acetylacetonate; toluene-4-sulfonic acid In water; toluene at 80℃; for 24h; Schlenk technique;	92%

: 110-61-2
butanedinitrile

: 98-80-6
phenylboronic acid

: 838-40-4
2,5-diphenyl-1H-pyrrole

Conditions

Conditions	Yield
With [2,2]bipyridinyl; palladium(II) trifluoroacetate; 2,2,2-trifluoroacetic acid ammonia; trifluoroacetic acid In tetrahydrofuran; water at 80℃; for 48h; Reagent/catalyst; Solvent; Schlenk technique;	92%

: 110-61-2
butanedinitrile

: 1225289-40-6
1-(3,3,3-trifluoropropynyl)-1-prop-2-ynyloxy-cyclohexane

: C28H30F6N2O2

Conditions

Conditions	Yield
With CoCl2(phen); zinc dibromide; zinc In 1,2-dichloro-ethane at 80℃; for 24h; Glovebox; regioselective reaction;	92%

: 110-61-2
butanedinitrile

: 109-94-4
formic acid ethyl ester

: formyl succinonitrile potassium salt

Conditions

Conditions	Yield
With potassium tert-butylate In toluene; tert-butyl alcohol at 0 - 20℃; for 4h;	91.2%

: 123-75-1
pyrrolidine

: 110-61-2
butanedinitrile

: 63958-62-3
1,4-dipyrrolidinyl-1,4-dioxobutane

Conditions

Conditions	Yield
With water; dihydridotetrakis(triphenylphosphine)ruthenium In 1,2-dimethoxyethane at 160℃; for 24h;	91%

: 110-61-2
butanedinitrile

: 23923-29-7
<2,2,3,3-(2)H4>succinonitrile

Conditions

Conditions	Yield
With [carbonylchlorohydrido{bis[2-(diphenylphosphinomethyl)ethyl]amino}ethylamino] ruthenium(II); potassium tert-butylate; water-d2 at 70℃; for 24h; Inert atmosphere;	91%
With water-d2 for 96h; Heating;	85%
With water-d2; 1,8-diazabicyclo[5.4.0]undec-7-ene In 1,4-dioxane for 24h; Heating;	75%
With 1,2-diazabicyclo[5.4.0]undec-7-ene; water-d2 In 1,4-dioxane for 49h; Heating;	57%
With potassium deuteroxide; water-d2 for 4h; Ambient temperature;

: 110-61-2
butanedinitrile

: ammonium hexafluorophosphate

: 59460-48-9
bis(2,2'-bipyridine)carbonatoruthenium(II)

: 1493-13-6
trifluorormethanesulfonic acid

: bis(2,2'-bipyridine)bis(succinonitrile)ruthenium(II) hexafluorophosphate

Conditions

Conditions	Yield
In methanol; water byproducts: CO2; soln. of Ru compd. (0.230 mmol) in dry MeOH stirred at room temp. for 30min under Ar, triflic acid added, mixt. stirred for 3 h, succinonitrile (0.750 mmol) added, mixt. refluxed overnight, concd., aq. satd. soln. o f NH4PF6 added; ppt. filtered off, washed with Et2O, dried under vac.; elem. anal.;	90%

...Expand

: 110-61-2
butanedinitrile

: adamantane

: N-(adamantan-1-yl)butanediamide

Conditions

Conditions	Yield
Stage #1: adamantane With nitric acid at 15 - 20℃; Ritter Amidation; Stage #2: butanedinitrile at 25℃; for 2h;	90%

Succinonitrile Chemical Properties

Molecular Formula: C₄H₄N₂
Molar mass: 80.088 g/mol
Density: 0.984 g/cm³
Flash Point: 141.1 °C
Index of Refraction: 1.415
Melting point: 50-54 °C(lit.)
storage temp: 2-8°C
Water solubility: slightly soluble
Boiling Point: 268.5 °C at 760 mmHg
Vapour Pressure: 0.00767 mmHg at 25°C
Solubility: methanol: 0.1 g/mL, clear,colorless
Appearance: almost white to brown crystalline solid
Structure of Succinonitrile (CAS NO.110-61-2):

Product Categories of Succinonitrile (CAS NO.110-61-2): Dinitriles & Trinitriles
Synonyms of Succinonitrile (CAS NO.110-61-2): 1,2-Dicyanoethane 1,4-Butanedinitrile ; Butanedinitrile ; Deprelin ; Disuxyl ; Ethane, 1,2-dicyano- ; Ethylene cyanide ; Succinic acid dinitrile ; Succinic acid nitrile ; Succinodinitrile ; Succinonitrile ; Sukcinonitril ; s-Dicyanoethane .

Succinonitrile Production

Succinonitrile(110-61-2) is produced by the addition of hydrogen cyanide to acrylonitrile.
CH₂=CHCN + HCN → NCCH₂CH₂CN

Succinonitrile Toxicity Data With Reference

dog	LDLo	subcutaneous	150mg/kg (150mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: NAUSEA OR VOMITING	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 3, Pg. 77, 1897.
frog	LDLo	subcutaneous	1gm/kg (1000mg/kg)		Archives Internationales de Pharmacodynamie et de Therapie. Vol. 3, Pg. 77, 1897.
mouse	LD50	intraperitoneal	63110ug/kg (63.11mg/kg)	KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION	Biochemical Pharmacology. Vol. 27, Pg. 1135, 1978.
mouse	LD50	oral	129mg/kg (129mg/kg)		Archives of Toxicology. Vol. 57, Pg. 88, 1985.
pigeon	LDLo	subcutaneous	2200mg/kg (2200mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: NAUSEA OR VOMITING	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 3, Pg. 77, 1897.
rabbit	LDLo	subcutaneous	36mg/kg (36mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 3, Pg. 77, 1897.
rat	LCLo	inhalation	730mg/m3/4H (730mg/m3)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA	National Technical Information Service. Vol. OTS0570875,
rat	LD50	oral	450mg/kg (450mg/kg)		"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2C, Pg. 4879, 1982.

Succinonitrile Consensus Reports

Cyanide and its compounds are on the Community Right-To-Know List. Reported in EPA TSCA Inventory.

Succinonitrile Safety Profile

Hazard Codes: Harmful Xn
Risk Statements: 22-36/37/38-36/38-20/21/22
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
R36/38:Irritating to eyes and skin.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-36/37-45-36/37/39-22
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37:Wear suitable protective clothing and gloves.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S22:Do not breathe dust.
RIDADR: 3276
WGK Germany: 3
RTECS: WN3850000
HazardClass: 6.1
PackingGroup: III
HS Code: 29051900
HS Code: 29269095
Poison by ingestion, intraperitoneal, and subcutaneous routes. An experimental teratogen. Combustible when exposed to heat or flame. Decomposes exothermically above 195°C. Can react with oxidizing materials. To fight fire, use alcohol foam, CO₂, dry chemical. When heated to decomposition, or on contact with acid or acid fumes, it emits highly toxic fumes of NO_x and CN⁻. See also NITRILES.

Succinonitrile Standards and Recommendations

ACGIH TLV: CL 5 mg(CN)/m³ (skin)
NIOSH REL: (Nitriles) TWA 20 mg/m³

Succinonitrile Specification

Succinonitrile (CAS NO.110-61-2) is hazardous,so the first aid measures and others should be known .Such as:
Skin: Get medical aid. Should flush skin with plenty of water immediatelyfor at least 15 minutes while removing contaminated clothing and shoes.
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.Then get medical aid soon.
Inhalation: Remove from exposure and move to fresh air immediately.Give artificial respiration While not breathing. when breathing is difficult, give oxygen.And as soon as to get medical aid.
Ingestion: Wash mouth out with water,and get medical aid immediately.
Notes to Physician: Treat supportively and symptomatically.
Chemical Stability: Stable under normal pressures and temperatures.
Incompatibilities with Other Materials: Strong reducing agents, strong bases, strong acids,strong oxidizing agents.
Conditions to Avoid: Incompatible materials,moisture.
Hazardous Decomposition Products: Nitrogen,oxides of phosphorus, hydrogen iodide, oxides of nitrogen, carbon dioxide, carbon monoxide.

Product Name

1,4-Butanedinitrile

Synthetic route

Succinonitrile Chemical Properties

Succinonitrile Production

Succinonitrile Toxicity Data With Reference

Succinonitrile Consensus Reports

Succinonitrile Safety Profile

Succinonitrile Standards and Recommendations

Succinonitrile Specification

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