Product Name

  • Name

    Triphenylphosphine oxide

  • EINECS 212-338-8
  • CAS No. 791-28-6
  • Article Data1217
  • CAS DataBase
  • Density 1.17g/cm3
  • Solubility slightly soluble in water
  • Melting Point 154-158 °C
  • Formula C18H15OP
  • Boiling Point 462.9 °C at 760 mmHg
  • Molecular Weight 278.29
  • Flash Point 233.8 °C
  • Transport Information
  • Appearance White solid
  • Safety 26-61-36
  • Risk Codes 22-36/37/38-52/53
  • Molecular Structure Molecular Structure of 791-28-6 (Triphenylphosphine oxide)
  • Hazard Symbols HarmfulXn, IrritantXi
  • Synonyms phosphorane, triphenyl-, oxide;diphenylphosphorylbenzene;TPPO;Triphenyl phosphorus oxide;Phosphine oxide, triphenyl-;
  • PSA 26.88000
  • LogP 3.32600

Synthetic route

triphenylphosphine
603-35-0

triphenylphosphine

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
With CuO2H In acetonitrile at 70℃; for 6h;100%
With CuO2H In acetonitrile at 70℃; for 6h;100%
With periodate form of Amberlyst A26 In chloroform at 25℃; for 2h;100%
Triphenylphosphine selenide
3878-44-2

Triphenylphosphine selenide

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
With pyridine; trifluoroacetic anhydride for 2h;100%
With hexyl sulfide; oxygen In methanol; chloroform for 0.5h; Irradiation;100%
With hexyl sulfide In methanol; chloroform for 1h; Product distribution; Irradiation; other reagents;100%
9-fluorenone triphenylphosphazine
751-35-9

9-fluorenone triphenylphosphazine

A

9-fluorenone
486-25-9

9-fluorenone

B

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
With oxygen; methylene blue In dichloromethane at -78℃; for 0.0833333h; Irradiation; other reagent;A 100%
B n/a
With oxygen; methylene blue In dichloromethane Quantum yield; Irradiation;
triphenylphosphine
603-35-0

triphenylphosphine

A

triphenylphosphine oxide hydrobromide

triphenylphosphine oxide hydrobromide

B

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
With bromonitromethane In benzeneA 100%
B 88%
With bromonitromethane In benzene for 12h; Yield given. Yields of byproduct given;
triphenylphosphine sulfide
3878-45-3

triphenylphosphine sulfide

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
With 3-chloro-benzenecarboperoxoic acid In dichloromethane for 20h; Mechanism; other thiophosphoramides are also investigated;100%
With 3,3-dimethyldioxirane In dichloromethane; acetone for 0.0833333h; Ambient temperature;100%
With pyridine; trifluoroacetic anhydride for 3h;100%
[bis(acetoxy)iodo]benzene
3240-34-4

[bis(acetoxy)iodo]benzene

triphenylphosphine
603-35-0

triphenylphosphine

benzylamine
100-46-9

benzylamine

A

N-(phenylmethyl)acetamide
588-46-5

N-(phenylmethyl)acetamide

B

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
Stage #1: [bis(acetoxy)iodo]benzene; triphenylphosphine In chloroform for 1h; Heating;
Stage #2: benzylamine In chloroform for 0.166667h;
A 94%
B 100%
3,3-diphenyl-1,2-indanedione
7312-39-2

3,3-diphenyl-1,2-indanedione

methyl (triphenylphosphoranylidene)acetate
21204-67-1

methyl (triphenylphosphoranylidene)acetate

A

(E)-(3,3-diphenyl-2-oxoindan-1-ylidene)acetic acid methyl ester

(E)-(3,3-diphenyl-2-oxoindan-1-ylidene)acetic acid methyl ester

B

(Z)-(3,3-diphenyl-2-oxoindan-1-ylidene)acetic acid methyl ester

(Z)-(3,3-diphenyl-2-oxoindan-1-ylidene)acetic acid methyl ester

C

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
In benzene at 20℃; for 5h; Wittig reaction;A 70%
B 11%
C 100%
3,3-diphenyl-1,2-indanedione
7312-39-2

3,3-diphenyl-1,2-indanedione

ethyl (triphenylphosphoranylidene)acetate
1099-45-2

ethyl (triphenylphosphoranylidene)acetate

A

(E)-(3,3-diphenyl-2-oxoindan-1-ylidene)acetic acid ethyl ester

(E)-(3,3-diphenyl-2-oxoindan-1-ylidene)acetic acid ethyl ester

B

(Z)-(3,3-diphenyl-2-oxoindan-1-ylidene)acetic acid ethyl ester

(Z)-(3,3-diphenyl-2-oxoindan-1-ylidene)acetic acid ethyl ester

C

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
In benzene at 20℃; for 5h; Wittig reaction;A 65%
B 14%
C 100%
3,3-diphenyl-1,2-indanedione
7312-39-2

3,3-diphenyl-1,2-indanedione

cyanomethylene triphenylphosphorane
16640-68-9

cyanomethylene triphenylphosphorane

A

(E)-(3,3-diphenyl-2-oxoindan-1-ylidene)acetonitrile

(E)-(3,3-diphenyl-2-oxoindan-1-ylidene)acetonitrile

B

(Z)-(3,3-diphenyl-2-oxoindan-1-ylidene)acetonitrile

(Z)-(3,3-diphenyl-2-oxoindan-1-ylidene)acetonitrile

C

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
In benzene at 20℃; for 7h; Wittig reaction;A 63%
B 17%
C 100%
(Z)-3-(4-bromophenyl)-3-iodoprop-2-en-1-ol
452296-51-4

(Z)-3-(4-bromophenyl)-3-iodoprop-2-en-1-ol

A

1-bromo-4-((Z)-3-bromo-1-iodopropenyl)benzene
869209-22-3

1-bromo-4-((Z)-3-bromo-1-iodopropenyl)benzene

B

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
With carbon tetrabromide; triphenylphosphine In dichloromethane at 0 - 20℃;A 100%
B n/a
(x)CrO(2+)*(x)H2O

(x)CrO(2+)*(x)H2O

triphenylphosphine
603-35-0

triphenylphosphine

A

(x)Cr(2+)*(x)H2O

(x)Cr(2+)*(x)H2O

B

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
In perchloric acid; acetonitrile Kinetics; room temp.;A n/a
B 100%
C46H80CeCl2Co2I2O20P6*CH2Cl2

C46H80CeCl2Co2I2O20P6*CH2Cl2

triphenylphosphine
603-35-0

triphenylphosphine

A

[CeIV(Co(η5-C5H5){PO(OEt)2}3)2Cl2]

[CeIV(Co(η5-C5H5){PO(OEt)2}3)2Cl2]

B

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
In [D3]acetonitrile at 20℃; for 0.0833333h; Inert atmosphere; Schlenk technique;A n/a
B 100%
C42H89CeClIN3O7P6

C42H89CeClIN3O7P6

triphenylphosphine
603-35-0

triphenylphosphine

A

Ce[N(i-Pr2PO)2]3Cl
1361254-54-7

Ce[N(i-Pr2PO)2]3Cl

B

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
In [D3]acetonitrile at 20℃; for 0.0833333h; Inert atmosphere; Schlenk technique;A n/a
B 100%
phenylsulfenyl methyl thiocarbonate
61775-35-7

phenylsulfenyl methyl thiocarbonate

A

thiophenol
108-98-5

thiophenol

B

triphenylphosphine sulfide
3878-45-3

triphenylphosphine sulfide

C

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
With triphenylphosphine In benzene Mechanism; Ambient temperature; reaction of var. sulfenyl thiocarbonates with triphenylphosphine;A 99%
B 1%
C 99%
phenyl isocyanate
103-71-9

phenyl isocyanate

{[2-(4-Methylphenyl)-1-phenylvinyl]imino}triphenylphosphoran
105516-47-0

{[2-(4-Methylphenyl)-1-phenylvinyl]imino}triphenylphosphoran

A

Phenyl-((E)-1-phenyl-2-p-tolyl-vinyl)-carbodiimide
105516-54-9

Phenyl-((E)-1-phenyl-2-p-tolyl-vinyl)-carbodiimide

B

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
In benzene for 2h; Ambient temperature;A 90%
B 99%
N-(1,2-Diphenylvinyl)iminotriphenylphosphoran
26740-23-8

N-(1,2-Diphenylvinyl)iminotriphenylphosphoran

p-Tolylisocyanate
622-58-2

p-Tolylisocyanate

A

((E)-1,2-Diphenyl-vinyl)-p-tolyl-carbodiimide
105516-49-2

((E)-1,2-Diphenyl-vinyl)-p-tolyl-carbodiimide

B

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
In benzene for 2h; Ambient temperature;A 97%
B 99%
1,1,3,3-tetramethyl-2-indanone triphenyl-phosphoranylidenehydrazone
74768-85-7

1,1,3,3-tetramethyl-2-indanone triphenyl-phosphoranylidenehydrazone

A

2,2,5,5,-tetramethyl-3,4-benzo-3-penten-5-olide
4355-41-3

2,2,5,5,-tetramethyl-3,4-benzo-3-penten-5-olide

B

1,1,3,3-tetramethylindane-2-one
5689-12-3

1,1,3,3-tetramethylindane-2-one

C

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
With oxygen In dichloromethane at 15℃; for 16h; Irradiation;A 9%
B 68%
C 99%
With oxygen; methylene blue In dichloromethane at 15℃; for 16h; Irradiation;A 9%
B 68%
C 99%
With oxygen; methylene blue In dichloromethane at 15℃; for 16h; Product distribution; Mechanism; Irradiation; various sensitizers;
trans-tetrachlorobis(pyridine)platinum(II)
16893-32-6, 17100-03-7, 19306-93-5

trans-tetrachlorobis(pyridine)platinum(II)

methyl (triphenylphosphoranylidene)acetate
21204-67-1

methyl (triphenylphosphoranylidene)acetate

trans-dichlorobis(pyridine)platinum(II)
14024-97-6, 14872-21-0, 15227-42-6

trans-dichlorobis(pyridine)platinum(II)

B

(2-methoxy-2-oxoethyl)triphenylphosphonium chloride
2181-97-7

(2-methoxy-2-oxoethyl)triphenylphosphonium chloride

C

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
In dichloromethane Ph3P=CHCO2Me was added to soln. Pt(IV) complex in CH2Cl2, react. mixt. was kept at room temp. for 3 h; solvent was evapd., residue was chromed. on silica using CH2Cl2/Et2O (9:1) as eluent;A 99%
B n/a
C n/a
trans-tetrachlorobis(dimethyl sulfide) platinum(IV)
16893-23-5, 16893-33-7, 55903-49-6

trans-tetrachlorobis(dimethyl sulfide) platinum(IV)

methyl (triphenylphosphoranylidene)acetate
21204-67-1

methyl (triphenylphosphoranylidene)acetate

trans-dichlorobis(dimethylsulfide)platinum(II)
17836-09-8, 17457-51-1, 55449-91-7

trans-dichlorobis(dimethylsulfide)platinum(II)

B

(2-methoxy-2-oxoethyl)triphenylphosphonium chloride
2181-97-7

(2-methoxy-2-oxoethyl)triphenylphosphonium chloride

C

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
In dichloromethane Ph3P=CHCO2Me was added to soln. Pt(IV) complex in CH2Cl2, react. mixt. was kept at room temp. for 3 h; solvent was evapd., residue was chromed. on silica using CH2Cl2/Et2O (9:1) as eluent;A 99%
B n/a
C n/a
methyl (triphenylphosphoranylidene)acetate
21204-67-1

methyl (triphenylphosphoranylidene)acetate

trans-dichloro(dimethyl sulfide-κS)(pyridine-κ-N)platinum(II)
31203-94-8, 161345-43-3, 31203-93-7

trans-dichloro(dimethyl sulfide-κS)(pyridine-κ-N)platinum(II)

B

(2-methoxy-2-oxoethyl)triphenylphosphonium chloride
2181-97-7

(2-methoxy-2-oxoethyl)triphenylphosphonium chloride

C

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
In dichloromethane Ph3P=CHCO2Me was added to soln. Pt(IV) complex in CH2Cl2, react. mixt. was kept at room temp. for 3 h; solvent was evapd., residue was chromed. on silica using CH2Cl2/Et2O (9:1) as eluent;A 99%
B n/a
C n/a
trans-(PtCl4(HON=CMe2)2)
135848-70-3, 143169-60-2

trans-(PtCl4(HON=CMe2)2)

methyl (triphenylphosphoranylidene)acetate
21204-67-1

methyl (triphenylphosphoranylidene)acetate

(SP-4-1)-bis(acetone oxime-κN)dichloridoplatinum(II)
15022-74-9, 15022-73-8

(SP-4-1)-bis(acetone oxime-κN)dichloridoplatinum(II)

B

(2-methoxy-2-oxoethyl)triphenylphosphonium chloride
2181-97-7

(2-methoxy-2-oxoethyl)triphenylphosphonium chloride

C

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
In dichloromethane Ph3P=CHCO2Me was added to soln. Pt(IV) complex in CH2Cl2, react. mixt. was kept at room temp. for 3 h; solvent was evapd., residue was chromed. on silica using CH2Cl2/Et2O (9:1) as eluent;A 99%
B n/a
C n/a
trans-(PtCl4(Me2SO)(NHEt2))

trans-(PtCl4(Me2SO)(NHEt2))

methyl (triphenylphosphoranylidene)acetate
21204-67-1

methyl (triphenylphosphoranylidene)acetate

trans-(PtCl2(Me2SO)(NHEt2))
337526-17-7

trans-(PtCl2(Me2SO)(NHEt2))

B

(2-methoxy-2-oxoethyl)triphenylphosphonium chloride
2181-97-7

(2-methoxy-2-oxoethyl)triphenylphosphonium chloride

C

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
In dichloromethane Ph3P=CHCO2Me was added to soln. Pt(IV) complex in CH2Cl2, react. mixt. was kept at room temp. for 3 h; solvent was evapd., residue was chromed. on silica using CH2Cl2/Et2O (9:1) as eluent;A 99%
B n/a
C n/a
(PtCl4(NC(CH3)ON(CH3)CHC6H5)2)
270064-62-5, 267238-07-3

(PtCl4(NC(CH3)ON(CH3)CHC6H5)2)

methyl (triphenylphosphoranylidene)acetate
21204-67-1

methyl (triphenylphosphoranylidene)acetate

A

(PtCl2(NC(CH3)ON(CH3)CHC6H5)2)
324764-91-2

(PtCl2(NC(CH3)ON(CH3)CHC6H5)2)

B

(2-methoxy-2-oxoethyl)triphenylphosphonium chloride
2181-97-7

(2-methoxy-2-oxoethyl)triphenylphosphonium chloride

C

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
In dichloromethane Ph3P=CHCO2Me was added to soln. Pt(IV) complex in CH2Cl2, react. mixt. was kept at room temp. for 3 h; solvent was evapd., residue was chromed. on silica using CH2Cl2/Et2O (9:1) as eluent;A 99%
B n/a
C n/a
2-methoxy-6-phenylpyrimidin-4-ol
1044559-21-8

2-methoxy-6-phenylpyrimidin-4-ol

17-hydroxy-13-methyl-2,14-dioxo-3,13,15-triaza-tricyclo[13.3.0.0*4.6*]-octadec-7-ene-4-carboxylic acid ethyl ester
922726-54-3

17-hydroxy-13-methyl-2,14-dioxo-3,13,15-triaza-tricyclo[13.3.0.0*4.6*]-octadec-7-ene-4-carboxylic acid ethyl ester

triphenylphosphine
603-35-0

triphenylphosphine

A

14-(4-methoxy-benzyl)-18-(2-methoxy-6-phenyl-pyrimidin-4-yloxy)-2,15-dioxo-3,14,16-triaza-tricyclo[14.3.0.0*4,6*]nonadec-7-ene-4-carboxylic acid ethyl ester
1044559-31-0

14-(4-methoxy-benzyl)-18-(2-methoxy-6-phenyl-pyrimidin-4-yloxy)-2,15-dioxo-3,14,16-triaza-tricyclo[14.3.0.0*4,6*]nonadec-7-ene-4-carboxylic acid ethyl ester

B

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate In tetrahydrofuran; N,N-dimethyl-formamide at 20℃;A 99%
B n/a
4-Phenylbenzaldehyde
3218-36-8

4-Phenylbenzaldehyde

methyl (triphenylphosphoranylidene)acetate
21204-67-1

methyl (triphenylphosphoranylidene)acetate

A

methyl (E)-3-([1′,1′′-biphenyl]-4′-yl)acrylate
20883-99-2, 22837-75-8

methyl (E)-3-([1′,1′′-biphenyl]-4′-yl)acrylate

B

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
In dichloromethane at 20℃; Wittig reaction; Inert atmosphere;A 99%
B n/a
4-methoxy-o-phenyl phenyl(phenyl)phosphinate
34253-15-1

4-methoxy-o-phenyl phenyl(phenyl)phosphinate

phenylmagnesium bromide
100-58-3

phenylmagnesium bromide

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
In tetrahydrofuran at 0 - 20℃; Inert atmosphere;99%
pyridine-3,5-bis-carbaldehyde
6221-04-1

pyridine-3,5-bis-carbaldehyde

(3-carboxypropyl)(triphenyl)phosphonium bromide
17857-14-6

(3-carboxypropyl)(triphenyl)phosphonium bromide

A

(E)-5-[5-((E)-4-Carboxy-but-1-enyl)-pyridin-3-yl]-pent-4-enoic acid

(E)-5-[5-((E)-4-Carboxy-but-1-enyl)-pyridin-3-yl]-pent-4-enoic acid

B

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
With sodium hydride In dimethyl sulfoxide; N,N-dimethyl-formamide at 50℃; for 28h;A 0.278 g
B 98%
1,1,1-trifluoroacetophenone
434-45-7

1,1,1-trifluoroacetophenone

benzyltriphenylphosphonium bromide
1449-46-3

benzyltriphenylphosphonium bromide

A

1,2-diphenyl-3,3,3-trifluoroprop-1-ene
77542-08-6

1,2-diphenyl-3,3,3-trifluoroprop-1-ene

B

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
With water; potassium carbonate In 1,4-dioxane at 95℃; for 3h;A 98%
B n/a
n-butyl(triphenyl)phosphonium bromide
1779-51-7

n-butyl(triphenyl)phosphonium bromide

benzaldehyde
100-52-7

benzaldehyde

A

(Z)-pent-1-en-1-ylbenzene
7642-18-4

(Z)-pent-1-en-1-ylbenzene

B

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
With water; potassium carbonate In 1,4-dioxane Product distribution; Mechanism; further aldehydes and ketones; other solvents; other alkaline carbonates as reagens; stereoselectivity examined;A 98%
B n/a
Cyclohexyl isocyanate
3173-53-3

Cyclohexyl isocyanate

{[2-(4-Methylphenyl)-1-phenylvinyl]imino}triphenylphosphoran
105516-47-0

{[2-(4-Methylphenyl)-1-phenylvinyl]imino}triphenylphosphoran

A

Cyclohexyl-((E)-1-phenyl-2-p-tolyl-vinyl)-carbodiimide
105516-58-3

Cyclohexyl-((E)-1-phenyl-2-p-tolyl-vinyl)-carbodiimide

B

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

Conditions
ConditionsYield
In benzene Ambient temperature;A 94%
B 98%
Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

triphenylphosphine
603-35-0

triphenylphosphine

Conditions
ConditionsYield
With 1,1,3,3-Tetramethyldisiloxane; titanium(IV) isopropylate In various solvent(s) at 100℃; for 5h;100%
With aluminium hydride*tetrahydrofuran100%
With titanium(IV) isopropylate; 1,1,3,3-Tetramethyldisiloxane In methyl cyclohexane at 80℃; for 14h;100%
Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

methyl trifluoromethanesulfonate
333-27-7

methyl trifluoromethanesulfonate

methoxytriphenylphosphonium trifluoromethanesulfonate
81324-89-2

methoxytriphenylphosphonium trifluoromethanesulfonate

Conditions
ConditionsYield
In dichloromethane at 20℃; for 3h;100%
In benzene Heating;90%
In acetonitrile89%
In acetonitrile at 20℃; for 1h; Inert atmosphere;
benzene-1,2-diol
120-80-9

benzene-1,2-diol

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

triphenyl(1,2-phenylenedioxy)phosphorane
62785-50-6

triphenyl(1,2-phenylenedioxy)phosphorane

Conditions
ConditionsYield
at 70 - 80℃; for 2h;100%
2,3-naphthalenediol
92-44-4

2,3-naphthalenediol

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

(2,3-naphthalenedioxy)triphenylphosphorane

(2,3-naphthalenedioxy)triphenylphosphorane

Conditions
ConditionsYield
at 100 - 110℃; for 2h;100%
1-bromo-3,4-dihydroxybenzene
17345-77-6

1-bromo-3,4-dihydroxybenzene

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

(4-bromo-1,2-phenylenedioxy)triphenylphosphorane

(4-bromo-1,2-phenylenedioxy)triphenylphosphorane

Conditions
ConditionsYield
at 70 - 80℃; for 2h;100%
3-bromo-5-tert-butyl-1,2-dihydroxybenzene
38475-36-4

3-bromo-5-tert-butyl-1,2-dihydroxybenzene

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

(3-bromo-5-tert-butyl-1,2-phenylenedioxy)triphenylphosphorane

(3-bromo-5-tert-butyl-1,2-phenylenedioxy)triphenylphosphorane

Conditions
ConditionsYield
at 70 - 80℃; for 2h;100%
1-cyclohexyl-3,4-dihydroxybenzene
1134-37-8

1-cyclohexyl-3,4-dihydroxybenzene

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

(4-cyclohexyl-1,2-phenylenedioxy)triphenylphosphorane

(4-cyclohexyl-1,2-phenylenedioxy)triphenylphosphorane

Conditions
ConditionsYield
at 70 - 80℃; for 2h;100%
Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

dichlorotriphenylphosphorane
2526-64-9

dichlorotriphenylphosphorane

Conditions
ConditionsYield
With oxalyl dichloride In acetonitrile at 20℃; Inert atmosphere;100%
With bis(trichloromethyl) carbonate In chloroform at 20℃; for 1h;
With oxalyl dichloride; tetrabutylammonium trifluoromethylsulfonate In acetonitrile at 20℃; for 0.166667h; Inert atmosphere;
With oxalyl dichloride In acetonitrile Inert atmosphere;
With oxalyl dichloride In acetonitrile at 0 - 5℃;
thiourea
17356-08-0

thiourea

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

2,2,2-triphenyl-1H-1,3,2,λ5-diazaphosphotidine-4-thione

2,2,2-triphenyl-1H-1,3,2,λ5-diazaphosphotidine-4-thione

Conditions
ConditionsYield
at 95 - 100℃; for 4h;100%
urea
57-13-6

urea

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

2,2,2-triphenyl-1H-1,3,2,λ5-diazaphosphotidin-4-one

2,2,2-triphenyl-1H-1,3,2,λ5-diazaphosphotidin-4-one

Conditions
ConditionsYield
at 95 - 100℃; for 4h;100%
uranium(IV) chloride
10026-10-5

uranium(IV) chloride

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

[UCl4(triphenylphosphine oxide)2]
58001-79-9, 85281-21-6, 16923-61-8

[UCl4(triphenylphosphine oxide)2]

Conditions
ConditionsYield
In tetrahydrofuran Glovebox;100%
In tetrahydrofuran inert atmosphere; stirring UCl4 for 24 h, Ph3PO addn. (pptn.); collection (filtration), washing (PhMe, hexane);94%
In tetrahydrofuran for 0.166667h;
ThCl4(dimethoxyethane)2

ThCl4(dimethoxyethane)2

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

ThCl4(triphenylphosphine oxide)3

ThCl4(triphenylphosphine oxide)3

Conditions
ConditionsYield
In tetrahydrofuran 3 equiv. Ph3PO;100%
trifluorormethanesulfonic acid
1493-13-6

trifluorormethanesulfonic acid

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

hydroxytriphenylphosphonium trifluoromethanesulfonate

hydroxytriphenylphosphonium trifluoromethanesulfonate

Conditions
ConditionsYield
In dichloromethane at 20℃; for 3h;100%
In toluene at 0 - 23℃; for 1h; Inert atmosphere; Schlenk technique;97%
3CF3O3S(1-)*C15H21N6P2(3+)

3CF3O3S(1-)*C15H21N6P2(3+)

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

A

2CF3O3S(1-)*C10H14N4O4P4(2+)

2CF3O3S(1-)*C10H14N4O4P4(2+)

B

CF3O3S(1-)*C23H22N2P(1+)
1353778-53-6

CF3O3S(1-)*C23H22N2P(1+)

Conditions
ConditionsYield
In dichloromethane at 20℃; for 20h; Inert atmosphere;A 100%
B 100%
[ThCl4(1,2-dimethoxyethane)2]
639084-65-4

[ThCl4(1,2-dimethoxyethane)2]

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

ThCl4(triphenylphosphine oxide)3

ThCl4(triphenylphosphine oxide)3

Conditions
ConditionsYield
In tetrahydrofuran at 20℃; for 6h;100%
trimethylsilyl iodide
16029-98-4

trimethylsilyl iodide

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

C21H24OPSi(1+)*I(1-)

C21H24OPSi(1+)*I(1-)

Conditions
ConditionsYield
In toluene for 0.166667h; Inert atmosphere; Schlenk technique; Glovebox;100%
UO2I2(tetrahydrofuran)3

UO2I2(tetrahydrofuran)3

Triphenylphosphine oxide
791-28-6

Triphenylphosphine oxide

UO2I2((C6H5)3PO)2

UO2I2((C6H5)3PO)2

Conditions
ConditionsYield
In tetrahydrofuran for 1h;100%

Triphenylphosphine oxide Chemical Properties

IUPAC Name: Diphenylphosphorylbenzene
Synonyms of Triphenyl Phosphine Oxide (CAS NO.791-28-6): 3-Acetylpropionic acid ; 4-Ketovaleric acid ; 4-Oxopentanoic acid ; Acetopropionic acid ; Levulinic acid ; Propionic acid, 3-acetyl- ; gamma-Ketovaleric acid
CAS NO: 791-28-6
Molecular Formula: C18H15OP
Molecular Weight: 791-28-6
Molecular Structure:
EINECS: 212-338-8
H bond acceptors: 1
H bond donors: 0
Freely Rotating Bonds: 3
Polar Surface Area: 26.88 Å2
Index of Refraction: 1.619
Molar Refractivity: 82.91 cm3
Molar Volume: 236.2 cm3
Surface Tension: 48.2 dyne/cm
Density: 1.17 g/cm3
Flash Point: 233.8 °C
Enthalpy of Vaporization: 69.63 kJ/mol
Boiling Point: 462.9 °C at 760 mmHg
Vapour Pressure: 2.62E-08 mmHg at 25°C
Melting point: 154-158 °C 
Storage temp: Store at RT
Solubility methanol: 25 mg/mL, clear
Water solubility: slightly soluble 
Appearance: White solid
Product Categories of Triphenyl Phosphine Oxide (CAS NO.791-28-6): Catalysis and Inorganic Chemistry;Phosphine Ligands;Phosphorus Compounds

Triphenylphosphine oxide Uses

 Triphenyl Phosphine Oxide (CAS NO.791-28-6) is used for intermediates in organic synthesis and pharmaceutical, and it is also used for catalysts, extraction agents. Besides, it is still used for fluorescent anti-counterfeit powder.

Triphenylphosphine oxide Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 450mg/kg (450mg/kg)   National Technical Information Service. Vol. AD607-952,
rabbit LD50 skin > 5gm/kg (5000mg/kg)   Food and Cosmetics Toxicology. Vol. 17, Pg. 847, 1979.
rat LD50 oral 1850mg/kg (1850mg/kg)   Food and Cosmetics Toxicology. Vol. 17, Pg. 847, 1979.

Triphenylphosphine oxide Safety Profile

Safety Information about Triphenyl Phosphine Oxide (CAS NO.791-28-6):
Hazard Codes: HarmfulXn,Xi
Risk Statements: 22-36/37/38-52/53
R22: Harmful if swallowed. 
R36/37/38: Irritating to eyes, respiratory system and skin. 
R52/53: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 26-61-36 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36: Wear suitable protective clothing. 
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
WGK Germany: 2
RTECS: SZ1676000
HS Code: 29310095

Triphenylphosphine oxide Specification

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. 
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage: Store in a cool, dry place. Store in a tightly closed container.

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