cis-Anethol supplier | CasNO.104-46-1

Name
Anethole
EINECS 203-205-5
CAS No. 104-46-1
Article Data69
CAS DataBase
Density 0.988 g/mL at 25 °C(lit.)
Solubility
Melting Point 20-21 °C(lit.)
Formula C₁₀H₁₂O
Boiling Point 237.5 °C at 760 mmHg
Molecular Weight 148.205
Flash Point 88.4 °C
Transport Information
Appearance Colourless,clear, liquid
Safety 36/37
Risk Codes 43
Molecular Structure
Hazard Symbols Xi
Synonyms Anise camphor;Isoestragole;NSC 4018;Nauli gum;Oil of aniseed;p-1-Propenylanisole;p-Anethole;p-Methoxy-b-methylstyrene;p-Propenylanisole;p-Propenylphenyl methyl ether;Anisole,p-propenyl- (8CI);Benzene, 1-methoxy-4-(1-propenyl)- (9CI);1-Methoxy-4-(1-propenyl)benzene;1-Methoxy-4-propenylbenzene;1-Propene,1-(4-methoxyphenyl)-;4-(1-Propenyl)anisole;4-Methoxy-1-propenylbenzene;4-Methoxypropenylbenzene;4-Propenylanisole;Anethol;
PSA 9.23000
LogP 2.72830

Synthetic route

: 863775-00-2
4-[(Z)-2-dodecylthioethenyl]anisole

: 75-16-1
methylmagnesium bromide

: 104-46-1
anethole

Conditions

Conditions	Yield
With bis(triphenylphosphine)nickel(II) chloride In diethyl ether for 12h; Heating;	90%

: C16H22N2O

A: 5519-42-6
3,4,5-Trimethylpyrazole

B: 104-46-1
anethole

Conditions

Conditions	Yield
With organo lithium reagent In hexane at 20℃; for 24h;	A 80% B 86%

: 590-14-7
1-bromo-1-propene

: 699-19-4
4-methoxyphenylmagnesium chloride

: 104-46-1
anethole

Conditions

Conditions	Yield
With 1-methyl-pyrrolidin-2-one; cobalt acetylacetonate In tetrahydrofuran at 15 - 20℃; for 0.25h;	80%

: 928-55-2
ethyl 1-propenyl ether

: 13139-86-1
4-methoxyphenyl magnesium bromide

: 104-46-1
anethole

Conditions

Conditions	Yield
With C68H72Cl2N6NiP2 In tetrahydrofuran at 50℃; for 12h; Inert atmosphere;	77%

: 7547-96-8, 7547-97-9, 88982-39-2, 6336-44-3
1-propenylboronic acid

: 623-12-1
4-chloromethoxybenzene

: 104-46-1
anethole

Conditions

Conditions	Yield
With tris(dibenzylideneacetone)dipalladium (0); caesium carbonate In 1,4-dioxane for 24h; Suzuki-Miyaura cross-coupling; Heating;	58%

: 74568-53-9
(E)-methyl 3-(3-bromo-4-hydroxyphenyl)acrylate

A: 140-67-0
Estragole

B: 74568-54-0
trans-2-bromo-4-(3-hydroxypropen-1-yl)phenol

C: 104-46-1
anethole

Conditions

Conditions	Yield
With aluminium hydride In diethyl ether for 1h; Ambient temperature; Yields of byproduct given;	A n/a B 48% C n/a

...Expand

: 24393-56-4, 51507-22-3, 1929-30-2
ethyl p-methoxycinnamate

A: 140-67-0
Estragole

B: 53484-50-7, 17581-85-0
p-methoxycinnamyl alcohol

C: 104-46-1
anethole

Conditions

Conditions	Yield
With aluminium hydride In diethyl ether for 0.5h; Ambient temperature; Yields of byproduct given;	A n/a B 47% C n/a

...Expand

: carbonic acid 1-(4-methoxy-phenyl)-allyl ester methyl ester

: 104-46-1
anethole

Conditions

Conditions	Yield
Stage #1: carbonic acid 1-(4-methoxy-phenyl)-allyl ester methyl ester With bis(1,5-cyclooctadiene)diiridium(I) dichloride; dibenzyl ether; N-isopropylidene-N’-2-nitrobenzenesulfonyl hydrazine In acetonitrile for 18h; Sealed tube; Inert atmosphere; Glovebox; Stage #2: With acetic acid In tetrahydrofuran; 2,2,2-trifluoroethanol; water for 2h; Sealed tube; Inert atmosphere; Glovebox; regioselective reaction;	45%

Yield

Stage #1: carbonic acid 1-(4-methoxy-phenyl)-allyl ester methyl ester With bis(1,5-cyclooctadiene)diiridium(I) dichloride; dibenzyl ether; N-isopropylidene-N’-2-nitrobenzenesulfonyl hydrazine In acetonitrile for 18h; Sealed tube; Inert atmosphere; Glovebox;
Stage #2: With acetic acid In tetrahydrofuran; 2,2,2-trifluoroethanol; water for 2h; Sealed tube; Inert atmosphere; Glovebox; regioselective reaction;

45%

: 104-92-7
1-bromo-4-methoxy-benzene

: 590-14-7
1-bromo-1-propene

: 104-46-1
anethole

Conditions

Conditions	Yield
With (2,2'-bipyridine)nickel(II) dibromide; tetrabutylammonium tetrafluoroborate In N,N-dimethyl-formamide at 70℃; i = 250 mA, nickel-sponge cathode;	44%

: 140-67-0
Estragole

A: 87797-12-4
1-methoxy-4-(4-(p-methoxyphenyl)but-3-enyl)benzene

B: 4705-34-4
4,4'-dimethoxystilbene

C: 34414-53-4
1,3-bis(4-methoxyphenyl)prop-1-ene

D: 104-46-1
anethole

E: 1,4-bis(4-methoxyphenyl)but-2-ene

Conditions

Conditions	Yield
With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride In toluene at 40℃; Inert atmosphere; Schlenk technique;	A n/a B n/a C n/a D n/a E 41%

...Expand

: 513-35-9
2-methyl-but-2-ene

: 123-11-5
4-methoxy-benzaldehyde

: 104-46-1
anethole

Conditions

Conditions	Yield
With trityl tetrafluoroborate In dichloromethane at -78℃; for 30h;	15%

: 110-86-1
pyridine

: 16031-55-3
1-(4-methoxyphenyl)prop-1-yl acetate

: 104-46-1
anethole

: 140-67-0
Estragole

: 104-46-1
anethole

Conditions

Conditions	Yield
With infusorial earht at 500℃;
iridium(III) chloride; β‐cyclodextrin In water at 95℃; for 2.5h;
PEG-KOH In potassium hydroxide; toluene at 65℃; Mechanism; Rate constant; variations of stirring rate, aqueous KOH concentration, and catalyst (7-130 oxyethylene units / PEG monomethyl, dimethyl, and dibenzyl ethers), other temp.; activation energy;

: [1-(4-methoxy-phenyl)-propyl]-dimethyl-amine

: 108-24-7
acetic anhydride

A: 127-19-5
N,N-dimethyl acetamide

B: 16031-55-3
1-(4-methoxyphenyl)prop-1-yl acetate

C: 104-46-1
anethole

...Expand

: 10467-10-4
ethylmagnesium iodide

: 123-11-5
4-methoxy-benzaldehyde

: 104-46-1
anethole

: 123-11-5
4-methoxy-benzaldehyde

: 123-62-6
propionic acid anhydride

: 104-46-1
anethole

Conditions

Conditions	Yield
With sodium proprionate

: 187737-37-7
propene

: 5780-90-5
(4-Methoxyphenyl)mercuric acetate

A: 140-67-0
Estragole

B: 1712-69-2
1-isopropenyl-4-methoxybenzene

C: 104-46-1
anethole

Conditions

Conditions	Yield
(i) Pd(OAc)2, MeCN, (ii) /BRN= 1696878/; Multistep reaction;

...Expand

: 140-67-0
Estragole

A: 123-11-5
4-methoxy-benzaldehyde

B: 104-46-1
anethole

Conditions

Conditions	Yield
With H2O2 or O2; copper dichloride; palladium dichloride In ethanol

: 1530-32-1
ethyltriphenylphosphonium bromide

: 123-11-5
4-methoxy-benzaldehyde

: 104-46-1
anethole

Conditions

Conditions	Yield
With n-butyllithium In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; hexane Yield given;
Stage #1: ethyltriphenylphosphonium bromide With potassium tert-butylate In tetrahydrofuran at 0℃; for 0.5h; Stage #2: 4-methoxy-benzaldehyde In tetrahydrofuran at 20℃; for 12h;

: 75619-30-6
Benzylidene-tris-(4-methoxy-phenyl)-λ5-phosphane

: 75-07-0
acetaldehyde

: 104-46-1
anethole

Conditions

Conditions	Yield
In tetrahydrofuran at 0℃; for 1h;	52 % Chromat.

: 1-(2-Diazo-1-methyl-ethyl)-4-methoxy-benzene

A: 1712-69-2
1-isopropenyl-4-methoxybenzene

B: 4030-17-5
4-methoxyphenylcyclopropane

C: 104-46-1
anethole

Conditions

Conditions	Yield
at 160℃; Yield given. Yields of byproduct given;

...Expand

α-methyl-β-<4-methoxy-phenyl>-acrylic acid: α-methyl-β-<4-methoxy-phenyl>-acrylic acid

: 104-46-1
anethole

ethyl-<4-methoxy-phenyl>-carbinol: ethyl-<4-methoxy-phenyl>-carbinol

: 104-46-1
anethole

Conditions

Conditions	Yield
With sulfuric acid durch Destillation;

ethyl-<4-methoxy-phenyl>--methyl-acetate: ethyl-<4-methoxy-phenyl>--methyl-acetate

: 104-46-1
anethole

Conditions

Conditions	Yield
With potassium carbonate
With pyridine

p-allyl-anisole: p-allyl-anisole

: 104-46-1
anethole

Conditions

Conditions	Yield
With potassium hydroxide

: 123-11-5
4-methoxy-benzaldehyde

ethyl magnesium halide (excessive): ethyl magnesium halide (excessive)

A: 104-46-1
anethole

B polymer(ic) anethole: polymer(ic) anethole

...Expand

: 140-67-0
Estragole

concentrated alcoholic KOH-solution: concentrated alcoholic KOH-solution

: 104-46-1
anethole

: 140-67-0
Estragole

infusorial earht: infusorial earht

: 104-46-1
anethole

Conditions

Conditions	Yield
at 500℃;

: 16031-55-3
1-(4-methoxyphenyl)prop-1-yl acetate

alcoholic KOH-solution: alcoholic KOH-solution

: 104-46-1
anethole

: 104-46-1
anethole

: 104-45-0
4-n-propylanisole

Conditions

Conditions	Yield
With C28H18Co(1-)K(1+)2C4H10O2; hydrogen In toluene at 60℃; under 7500.75 Torr; for 24h; chemoselective reaction;	99%
With sodium hydrogen telluride In ethanol Heating; overnight;	94%
With formic acid; Pd(SIPr)(PCy3) In tetrahydrofuran at 60℃; for 24h; Inert atmosphere;	94%

: 104-46-1
anethole

: 1201-60-1
1-(1,2-dibromopropyl)-4-methoxybenzene

Conditions

Conditions	Yield
With iodic acid; potassium bromide In dichloromethane; water at 20℃; for 0.166667h;	99%
With periodic acid; potassium bromide In dichloromethane; water at 20℃; for 0.133333h;	98%
With diethyl ether; bromine

: 89845-28-3
2-(2-phenylethynyl)-1,4-benzoquinone

: 104-46-1
anethole

: 1432504-68-1
2-(4-methoxyphenyl)-2-methyl-7-(phenylethynyl)-2,3-dihydrobenzofuran-5-ol

Conditions

Conditions	Yield
With bismuth(lll) trifluoromethanesulfonate In acetonitrile at 0℃; Inert atmosphere; Schlenk technique;	99%

: 802294-64-0
propionic acid

: 104-46-1
anethole

: 1446122-90-2
1-(4-methoxyphenyl)propan-2-yl propionate

Conditions

Conditions	Yield
Stage #1: propionic acid With 2,6-dimethylpyridine; 10-methyl-9-(2,4,6-trimethylphenyl) acridinium tetrafluoroborate; thiophenol In 1,2-dichloro-ethane at 0 - 23℃; for 0.25h; Inert atmosphere; Stage #2: anethole In 1,2-dichloro-ethane for 30h; Inert atmosphere; Irradiation; regioselective reaction;	99%

: 79-31-2
isobutyric Acid

: 104-46-1
anethole

: isobutyric acid 2-(4-methoxyphenyl)-1-methylethyl ester

Conditions

Conditions	Yield
Stage #1: isobutyric Acid With 2,6-dimethylpyridine; 10-methyl-9-(2,4,6-trimethylphenyl) acridinium tetrafluoroborate; thiophenol In 1,2-dichloro-ethane at 0 - 23℃; for 0.25h; Inert atmosphere; Stage #2: anethole In 1,2-dichloro-ethane for 62h; Inert atmosphere; Irradiation; regioselective reaction;	99%

: 887144-94-7
Togni's reagent II

: 104-46-1
anethole

: 1610846-52-0
3,3,3-trifluoro-1-(4-methoxyphenyl)-2-methylpropan-1-one

Conditions

Conditions	Yield
With tris[2-phenylpyridinato-C2,N]iridium(III); dimethyl sulfoxide at 20℃; for 2h; Irradiation; Green chemistry;	99%
With N9,N9,N10,N10-tetrakis(4-(tert-butyl)phenyl)anthracene-9,10-diamine; dimethyl sulfoxide In dichloromethane at 20℃; for 3h; Irradiation;	75%
With dmap; tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; magnesium sulfate In dimethyl sulfoxide at 20℃; for 48h; Solvent; Reagent/catalyst; Inert atmosphere; Irradiation;	40%

: 104-46-1
anethole

: 78-79-5
isoprene

: 112150-17-1
(1SR,2SR)-4'-methoxy-2,4-dimethyl-1,2,3,6-tetrahydro-1,1'-biphenyl

Conditions

Conditions	Yield
With N,N’,N’’-tris(3,5-bis(trifluoromethyl)phenyl)thiophosphoramide; [Ru(4,4'-bis(trifluoromethyl)-2,2'-bipyridine)3](3,5-bis(trifluoromethyl)benzenesulfonate)2 In dichloromethane at 20℃; for 0.333333h; Quantum yield; Reagent/catalyst; Diels-Alder Cycloaddition; Inert atmosphere; Irradiation;	99%
With tris(4-bromophenyl)ammoniumyl hexafluoroantimonate In dichloromethane for 1h; Quantum yield; Reagent/catalyst; Diels-Alder Cycloaddition; Irradiation;	35%

: 371-42-6
4-Fluorothiophenol

: 104-46-1
anethole

: (4-fluorophenyl)(1-(4-methoxyphenyl)propyl)sulfane

Conditions

Conditions	Yield
With copper(ll) bromide In acetonitrile at 20℃; for 2h; Schlenk technique; Inert atmosphere;	99%

: 106-54-7
p-Chlorothiophenol

: 104-46-1
anethole

: (4-chlorophenyl)(1-(4-methoxyphenyl)propyl)sulfane

Conditions

Conditions	Yield
With copper(ll) bromide In acetonitrile at 20℃; for 2h; Schlenk technique; Inert atmosphere;	99%

: 104-46-1
anethole

: 51410-46-9
2-(4-methoxyphenyl)-3-methyloxirane

Conditions

Conditions	Yield
With 3,3-dimethyldioxirane In acetone for 0.666667h; Ambient temperature;	98%
With dihydrogen peroxide; sodium hydrogencarbonate In acetonitrile
With oxidovanadium(IV)-β-octabromo-meso-tetrakis(2,6-dibromo-3,5-dimethoxyphenyl)porphyrin; dihydrogen peroxide; sodium hydrogencarbonate In water; acetonitrile at 60℃; for 0.5h; Catalytic behavior; Reagent/catalyst;

: 6111-99-5
ethyl diazoalaninate

: 104-46-1
anethole

: 5-ethoxy-2-(4-methoxyphenyl)-3,4-dimethyl-2,3-dihydrofuran

Conditions

Conditions	Yield
With tris(1,10-phenanthroline)iron(III) tris(hexafluorophosphate) In 1,2-dichloro-ethane at 0℃; for 6h;	98%

: 50-00-0
formaldehyd

: 104-46-1
anethole

: 5689-72-5
4-p-methoxyphenyl-5-methyl-1,3-dioxane

Conditions

Conditions	Yield
Lewatit SP 120 (acid form) In 1,4-dioxane at 60℃; for 0.5h;	97%
With sulfuric acid

: 935-50-2
4,4-dimethoxycyclohexa-2,5-dienone

: 104-46-1
anethole

: 1326704-90-8
2,3-dihydro-5-methoxy-2-(4-methoxyphenyl)-3-methylbenzofuran

Conditions

Conditions	Yield
With polystyrene-supported perfluorobenzoic acid In dichloromethane; 1,1,1,3',3',3'-hexafluoro-propanol at 0℃; chemoselective reaction;	97%
With 1,1,1,3',3',3'-hexafluoro-propanol; Pentafluorobenzoic acid In dichloromethane at 25℃; for 0.166667h;	93%

: 104-46-1
anethole

: 107-92-6
butyric acid

: 183471-68-3
1-(4-methoxyphenyl)propan-2-yl butyrate

Conditions

Conditions	Yield
Stage #1: butyric acid With 2,6-dimethylpyridine; 10-methyl-9-(2,4,6-trimethylphenyl) acridinium tetrafluoroborate; thiophenol In 1,2-dichloro-ethane at 0 - 23℃; for 0.25h; Inert atmosphere; Stage #2: anethole In 1,2-dichloro-ethane for 48h; Inert atmosphere; Irradiation; regioselective reaction;	97%

: 106-45-6
para-thiocresol

: 104-46-1
anethole

: (1-(4-methoxyphenyl)propyl)(p-tolyl)sulfane

Conditions

Conditions	Yield
With copper(ll) bromide In acetonitrile at 20℃; for 2h; Solvent; Schlenk technique; Inert atmosphere;	97%

: 104-46-1
anethole

: 25015-63-8
4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

: 1589553-46-7
(S)-2-(1-(4-methoxyphenyl)propyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Conditions

Conditions	Yield
With C24H31Cl2FeN3O2; sodium triethylborohydride In tetrahydrofuran at 20℃; for 1h; Inert atmosphere;	97%
With C26H28N4O; cobalt(II) acetate In diethyl ether at 20℃; for 18h; enantioselective reaction;	87%

: 1447990-65-9
C12H12O2

: 104-46-1
anethole

: 1432504-78-3
7-(3,3-dimethylbut-1-ynyl)-2-(4-methoxyphenyl)-2-methyl-2,3-dihydrobenzofuran-5-ol

Conditions

Conditions	Yield
With bismuth(lll) trifluoromethanesulfonate In acetonitrile at 0℃; Inert atmosphere; Schlenk technique;	96%

: 143427-14-9
3,6-Dioxo-cyclohexa-1,4-dienecarboxylic acid isopropyl ester

: 104-46-1
anethole

: C20H22O5

Conditions

Conditions	Yield
With C18H22N2O; copper(II) bis(trifluoromethanesulfonate) In toluene at -80℃; for 36h; Schlenk technique; Inert atmosphere; enantioselective reaction;	96%

: 104-46-1
anethole

: 252058-33-6, 305820-74-0
2-(4-methoxyphenyl)propanal

Conditions

Conditions	Yield
With iodine; silver(l) oxide In 1,4-dioxane; water for 4h; Ambient temperature;	95%
With N-iodo-succinimide; water; cetyltrimethylammonim bromide In 1,4-dioxane at 20 - 105℃; for 0.333333h; Microwave irradiation;	78%
With N-Bromosuccinimide; water; cetyltrimethylammonim bromide In dimethyl sulfoxide at 200℃; for 0.2h; Microwave irradiation;	65%

: 104-46-1
anethole

A: 51410-46-9
2-(4-methoxyphenyl)-3-methyloxirane

B: 252058-33-6, 305820-74-0
2-(4-methoxyphenyl)propanal

Conditions

Conditions	Yield
With iodine; silver(l) oxide In 1,4-dioxane; water for 4h; Product distribution; Ambient temperature; various bases, solvents and temp.;	A n/a B 95%
With sodium hydroxide; iodine for 2h; Ambient temperature;	A 10 % Chromat. B n/a

: 104-46-1
anethole

: 4705-34-4, 15638-14-9, 34480-01-8, 112246-67-0, 2510-75-0
1,2-bis(4-methoxyphenyl)ethene

Conditions

Conditions	Yield
With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride In neat (no solvent) at 90℃; for 1.33333h; Inert atmosphere;	95%

: 106-53-6
para-bromobenzenethiol

: 104-46-1
anethole

: (4-bromophenyl)(1-(4-methoxyphenyl)propyl)sulfane

Conditions

Conditions	Yield
With copper(ll) bromide In acetonitrile at 20℃; for 2h; Schlenk technique; Inert atmosphere;	95%

: C11H12O4

: 104-46-1
anethole

: C21H24O5

Conditions

Conditions	Yield
With C18H22N2O; copper(II) bis(trifluoromethanesulfonate) In toluene at -80℃; for 36h; Schlenk technique; Inert atmosphere; enantioselective reaction;	95%

: 3958-79-0
methyl 3,6-dioxocyclohexa-1,4-diene-1-carboxylate

: 104-46-1
anethole

: C18H18O5

Conditions

Conditions	Yield
With C18H22N2O; copper(II) bis(trifluoromethanesulfonate) In toluene at -80℃; for 36h; Schlenk technique; Inert atmosphere; enantioselective reaction;	95%

: 104-46-1
anethole

: 123-11-5
4-methoxy-benzaldehyde

Conditions

Conditions	Yield
With aluminum oxide; potassium permanganate In dichloromethane at 20℃; for 4h;	94%
With disodium hydrogenphosphate; oxygen; cobalt(II) acetate In methanol at 50℃; for 6h;	89.9%
With oxygen; ozone In water; ethyl acetate at 20℃; for 1.66667h;	81.7%

: 65-85-0
benzoic acid

: 104-46-1
anethole

: 1325210-54-5
1-(4-methoxyphenyl)propan-2-yl benzoate

Conditions

Conditions	Yield
Stage #1: benzoic acid With 2,6-dimethylpyridine; 10-methyl-9-(2,4,6-trimethylphenyl) acridinium tetrafluoroborate; thiophenol In 1,2-dichloro-ethane at 0 - 23℃; for 0.25h; Inert atmosphere; Stage #2: anethole In 1,2-dichloro-ethane for 30h; Inert atmosphere; Irradiation; regioselective reaction;	94%

: 870-50-8
di-tert-butyl-diazodicarboxylate

: 104-46-1
anethole

: di-tert-butyl 1-(2-azido-1-(4-methoxyphenyl)propyl)-hydrazine-1,2-dicarboxylate

Conditions

Conditions	Yield
With trimethylsilylazide; water; dimethylglyoxal In toluene at 20℃; for 8h; Inert atmosphere; Schlenk technique;	94%

: 524-38-9
N-hydroxyphthalimide

: 104-46-1
anethole

: C18H15NO4

Conditions

Conditions	Yield
With tert.-butylhydroperoxide; tetra-(n-butyl)ammonium iodide In water; acetonitrile at 100℃; for 2h;	93%

: 62830-98-2
2-ethoxycarbonyl-1,4-benzoquinone

: 104-46-1
anethole

: C19H20O5

Conditions

Conditions	Yield
With C18H22N2O; copper(II) bis(trifluoromethanesulfonate) In toluene at -80℃; for 36h; Schlenk technique; Inert atmosphere; enantioselective reaction;	93%

: 104-46-1
anethole

: 21086-33-9
2-bromo-1-(4-methoxyphenyl)-1-propanone

Conditions

Conditions	Yield
With N-Bromosuccinimide; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In dimethyl sulfoxide at 25 - 35℃; for 0.3h; regioselective reaction;	92%
With dipotassium peroxodisulfate; potassium bromide In water at 60℃; for 12h; Green chemistry;	21%
With bromine; ethyl acetate for 2h;	3.9%
Multi-step reaction with 2 steps 1: absolute diethyl ether; bromine 2: CrO3; glacial acetic acid View Scheme

cis-Anethol Chemical Properties

The Molecular formula of p-PROPENYLANISOLE(104-46-1):C₁₀H₁₂O
The Molecular Weight of p-PROPENYLANISOLE(104-46-1):148.2
The Molecular Structure of p-PROPENYLANISOLE(104-46-1) is:
Melting point:20-21 ^°C(lit.)
Boiling point:237.5 ^°C at 760 mmHg
Flash point:88.4 ^°C
Solubility in water:slightly water soluble .
Index of Refraction:1.545
Molar Refractivity:48.82 cm³
Molar Volume:154.4 cm³
Polarizability:19.35 10^-24cm³Surface Tension:31.8 dyne/cm
Enthalpy of Vaporization:45.51 kJ/mol
Vapour Pressure:0.0687 mmHg at 25^°C
Appearance:white crystals or a liquid
IUPAC Name:1-methoxy-4-[(E)-prop-1-enyl]benzene
Synonyms:P-METHOXYPROPENYLBENZENE;P-PROPENYLPHENYL METHYL ETHER;TRANS-1-METHOXY-4-(1-PROPENYL)BENZENE;TRANS-P-METHOXYPROPENYLBENZENE;TRANS-P-PROPENYLANISOLE;FEMA 2086;(E)-1-METHOXY-4-(1-PROPENYL)BENZENE;PARA METHOXY ALPHA PHENYL PROPENE

cis-Anethol Uses

It used as a toothpaste flavor, spice, also used for food, medicine, etc.

cis-Anethol Toxicity Data With Reference

1.	orl-rat LD50:2090 mg/kg	FCTXAV Food and Cosmetics Toxicology. 2 (1964),327.
2.	orl-mus LD50:3050 mg/kg	FCTXAV Food and Cosmetics Toxicology. 2 (1964),327.
3.	orl-gpg LD50:2160 mg/kg	FCTXAV Food and Cosmetics Toxicology. 2 (1964),327.
4.	orl-bwd LD50:316 mg/kg	AECTCV Archives of Environmental Contamination and Toxicology. 12 (1983),355.

cis-Anethol Consensus Reports

Reported in EPA TSCA Inventory.

cis-Anethol Safety Profile

Poison by ingestion. Questionable carcinogen with experimental tumorigenic data. Combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ETHERS.

Product Name

Anethole

Synthetic route

cis-Anethol Chemical Properties

cis-Anethol Uses

cis-Anethol Toxicity Data With Reference

cis-Anethol Consensus Reports

cis-Anethol Safety Profile

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