Product Name

  • Name

    4-N-PROPYLANISOLE

  • EINECS 203-203-4
  • CAS No. 104-45-0
  • Article Data125
  • CAS DataBase
  • Density 0.941 g/mL at 25 °C(lit.)
  • Solubility
  • Melting Point 45-46 °C
  • Formula C10H14 O
  • Boiling Point 215 °C(lit.)
  • Molecular Weight 150.221
  • Flash Point 194 °F
  • Transport Information
  • Appearance
  • Safety Mildly toxic by ingestion. Mutation data reported. Combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes.
  • Risk Codes 51/53
  • Molecular Structure Molecular Structure of 104-45-0 (4-N-PROPYLANISOLE)
  • Hazard Symbols DangerousN
  • Synonyms Anisole,p-propyl- (6CI,7CI,8CI); 1-Methoxy-4-propylbenzene; 4-Methoxy-1-propylbenzene;4-Propylanisole; 4-n-Propylanisole; Dihydroanethole; Methyl p-propylphenylether; NSC 37996; p-Propylanisole; p-Propylphenol methyl ether
  • PSA 9.23000
  • LogP 2.64770

Synthetic route

Estragole
140-67-0

Estragole

4-n-propylanisole
104-45-0

4-n-propylanisole

Conditions
ConditionsYield
With hydrogen; sodium triethylborohydride In tetrahydrofuran at 23℃; under 30003 Torr; for 96h; Reagent/catalyst; Autoclave;100%
With hydrogen; sodium triethylborohydride In tetrahydrofuran at 23℃; under 30402 Torr; for 18h; Catalytic behavior; Reagent/catalyst; Glovebox; Inert atmosphere;100%
With borane-ammonia complex; Pd(SIPr)(PCy3) In isopropyl alcohol at 50℃; for 16h; Inert atmosphere; Glovebox;99%
E-1-(4'-methoxyphenyl)prop-1-ene
4180-23-8

E-1-(4'-methoxyphenyl)prop-1-ene

4-n-propylanisole
104-45-0

4-n-propylanisole

Conditions
ConditionsYield
With magnesium; nickel dichloride In water at 20℃; for 12h; Sealed tube; Photolysis; Inert atmosphere;99%
With oxygen; hydrazine hydrate In propan-1-ol at 120℃; under 15001.5 Torr; for 0.5h;91%
With oxygen; hydrazine hydrate In propan-1-ol at 120℃; under 15001.5 Torr; for 0.166667h; Flow reactor;91%
anethole
104-46-1

anethole

4-n-propylanisole
104-45-0

4-n-propylanisole

Conditions
ConditionsYield
With C28H18Co(1-)*K(1+)*2C4H10O2; hydrogen In toluene at 60℃; under 7500.75 Torr; for 24h; chemoselective reaction;99%
With sodium hydrogen telluride In ethanol Heating; overnight;94%
With formic acid; Pd(SIPr)(PCy3) In tetrahydrofuran at 60℃; for 24h; Inert atmosphere;94%
1-methanesulfonyloxy-3-(4-methoxyphenyl)propane
72456-64-5

1-methanesulfonyloxy-3-(4-methoxyphenyl)propane

4-n-propylanisole
104-45-0

4-n-propylanisole

Conditions
ConditionsYield
With samarium diiodide; tri-n-butyl-tin hydride; lithium iodide In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide at 20 - 35℃; for 21h; Elimination;95%
2-phenyl-1,3,2-benzodioxaborole
5747-23-9

2-phenyl-1,3,2-benzodioxaborole

E-1-(4'-methoxyphenyl)prop-1-ene
4180-23-8

E-1-(4'-methoxyphenyl)prop-1-ene

A

4-n-propylanisole
104-45-0

4-n-propylanisole

B

phenol
108-95-2

phenol

Conditions
ConditionsYield
With oxygen; hydrazine hydrate In acetonitrile at 32℃; under 760.051 Torr; for 5h; Schlenk technique;A 95%
B 91%
4-chloromethoxybenzene
623-12-1

4-chloromethoxybenzene

propyl bromide
106-94-5

propyl bromide

4-n-propylanisole
104-45-0

4-n-propylanisole

Conditions
ConditionsYield
Stage #1: propyl bromide With chloro-trimethyl-silane; diisobutylaluminium hydride; magnesium; 1-Bromo-2-chloroethane In tetrahydrofuran at 40℃; Flow reactor;
Stage #2: With 1,3-bis[(2,6-diisopropyl)phenyl]imidazolinium chloride In tetrahydrofuran at 20℃; for 0.166667h; Inert atmosphere; Flow reactor;
Stage #3: 4-chloromethoxybenzene With iron(III)-acetylacetonate In tetrahydrofuran at 25℃; for 0.333333h; Inert atmosphere; Flow reactor; Irradiation;
95%
1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonic acid 4-methoxyphenyl ester
93131-74-9

1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonic acid 4-methoxyphenyl ester

propyl bromide
106-94-5

propyl bromide

4-n-propylanisole
104-45-0

4-n-propylanisole

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); 5-(dicyclohexylphosphaneyl)-1-(2,6-diisopropoxyphenyl)-1H-pyrazole; magnesium; lithium chloride; zinc(II) chloride In tetrahydrofuran at 25℃; for 24h; Inert atmosphere; Sealed tube; chemoselective reaction;93%
4-n-Propylphenol
645-56-7

4-n-Propylphenol

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

4-n-propylanisole
104-45-0

4-n-propylanisole

Conditions
ConditionsYield
With layered double hydroxide - supported L-methionine at 180℃; for 6h; Autoclave; chemoselective reaction;89%
1-bromo-4-methoxy-benzene
104-92-7

1-bromo-4-methoxy-benzene

n-propylmagnesium bromide
927-77-5

n-propylmagnesium bromide

4-n-propylanisole
104-45-0

4-n-propylanisole

Conditions
ConditionsYield
With palladium diacetate; zinc dibromide; tri tert-butylphosphoniumtetrafluoroborate In tetrahydrofuran at 20 - 25℃; for 2.5h; Inert atmosphere;88%
Estragole
140-67-0

Estragole

A

(Z)-1-(4-tolyl)-1-propene
2077-29-4

(Z)-1-(4-tolyl)-1-propene

B

(E)-1-methyl-4-(prop-1-enyl)benzene
2077-30-7

(E)-1-methyl-4-(prop-1-enyl)benzene

C

4-n-propylanisole
104-45-0

4-n-propylanisole

Conditions
ConditionsYield
With iron(III) chloride; lithium aluminium tetrahydride; hydrogen In tetrahydrofuran at 18℃; under 750.075 Torr; for 24h; Inert atmosphere; Sealed tube;A n/a
B n/a
C 84%
4-(p-methoxyphenyl)but-1-ene
20574-98-5

4-(p-methoxyphenyl)but-1-ene

4-n-propylanisole
104-45-0

4-n-propylanisole

Conditions
ConditionsYield
With iron(III)-acetylacetonate; ethanol; phenylsilane; thiophenol In propan-1-ol at 23℃; for 108h; Inert atmosphere;83%
isopropyl chloride
75-29-6

isopropyl chloride

4-methoxyphenyl triflate
66107-29-7

4-methoxyphenyl triflate

A

4-n-propylanisole
104-45-0

4-n-propylanisole

B

1-methoxy-4-(1-methylethyl)benzene
4132-48-3

1-methoxy-4-(1-methylethyl)benzene

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); 2-(dibutylphosphanyl)-1-phenylpyrrole; magnesium; lithium chloride; zinc(II) chloride In tetrahydrofuran at 60℃; for 16h; Reagent/catalyst; Inert atmosphere; Glovebox; Sealed tube;A 76%
B n/a
1-bromo-4-methoxy-benzene
104-92-7

1-bromo-4-methoxy-benzene

iso-propylmagnesium halide

iso-propylmagnesium halide

4-n-propylanisole
104-45-0

4-n-propylanisole

Conditions
ConditionsYield
With palladium diacetate; zinc dibromide; tri tert-butylphosphoniumtetrafluoroborate In tetrahydrofuran at 20 - 25℃; for 2.5h; Inert atmosphere;72%
cyclopropyl bromide
4333-56-6

cyclopropyl bromide

3-(4-methoxyphenyl)-1-iodopropane
113379-13-8

3-(4-methoxyphenyl)-1-iodopropane

A

4-n-propylanisole
104-45-0

4-n-propylanisole

B

1-(3-cyclopropylpropyl)-4-methoxybenzene

1-(3-cyclopropylpropyl)-4-methoxybenzene

Conditions
ConditionsYield
Stage #1: cyclopropyl bromide With iodine; magnesium In 2-methyltetrahydrofuran for 1.5h; Inert atmosphere; Reflux;
Stage #2: 3-(4-methoxyphenyl)-1-iodopropane With N,N,N,N,-tetramethylethylenediamine; cobalt(II) chloride In tetrahydrofuran; 2-methyltetrahydrofuran at 0℃; for 1h; Inert atmosphere; chemoselective reaction;
A 6%
B 69%
4-methoxyphenylcyclopropane
4030-17-5

4-methoxyphenylcyclopropane

4-n-propylanisole
104-45-0

4-n-propylanisole

Conditions
ConditionsYield
With C9H24B11N2(1+)*C24BF20(1-); hydrogen In benzene at 80℃; for 24h; Autoclave;69%
4-methoxyphenyl triflate
66107-29-7

4-methoxyphenyl triflate

isopropyl bromide
75-26-3

isopropyl bromide

A

4-n-propylanisole
104-45-0

4-n-propylanisole

B

1-methoxy-4-(1-methylethyl)benzene
4132-48-3

1-methoxy-4-(1-methylethyl)benzene

Conditions
ConditionsYield
With tris-(dibenzylideneacetone)dipalladium(0); 2-(dibutylphosphanyl)-1-phenylpyrrole; magnesium; lithium chloride; zinc(II) chloride In tetrahydrofuran at 60℃; for 16h; Reagent/catalyst; Inert atmosphere; Glovebox; Sealed tube;A 68%
B n/a
4-methoxy-α-ethylbenzyl methyl ether
88932-42-7

4-methoxy-α-ethylbenzyl methyl ether

4-n-propylanisole
104-45-0

4-n-propylanisole

Conditions
ConditionsYield
With triethylsilane; iron(III) chloride In dichloromethane at 20℃; for 1.5h;66%
With triethylsilane; iron(III) chloride In dichloromethane at 20℃; for 1.5h;66%
Estragole
140-67-0

Estragole

carbon monoxide
201230-82-2

carbon monoxide

A

4-n-propylanisole
104-45-0

4-n-propylanisole

B

3-(p-methoxyphenyl)-2-methylpropionaldehyde
5462-06-6

3-(p-methoxyphenyl)-2-methylpropionaldehyde

C

4-(4-methoxyphenyl)butyraldehyde
56047-51-9

4-(4-methoxyphenyl)butyraldehyde

D

E-1-(4'-methoxyphenyl)prop-1-ene
4180-23-8

E-1-(4'-methoxyphenyl)prop-1-ene

Conditions
ConditionsYield
With hydrogen; N-dodecyl-N-(2-hydroxyethyl)-N,N-dimethylammonium bromide; {Rh(cod)[μ-S(CH2)3Si(OMe)3]}2; triphenylphosphine In water; butan-1-ol at 80℃; under 10350.8 Torr; for 6h; microemulsion/sol-gel; Further byproducts given;A 1.4%
B 27.4%
C 63.8%
D 6.7%
1-bromo-4-methoxy-benzene
104-92-7

1-bromo-4-methoxy-benzene

1-propylmagnesium chloride
2234-82-4

1-propylmagnesium chloride

4-n-propylanisole
104-45-0

4-n-propylanisole

Conditions
ConditionsYield
With palladium diacetate; zinc dibromide; tri tert-butylphosphoniumtetrafluoroborate In tetrahydrofuran at 20 - 25℃; for 2.5h; Inert atmosphere;63%
4-n-Propylphenol
645-56-7

4-n-Propylphenol

tetramethlyammonium chloride
75-57-0

tetramethlyammonium chloride

4-n-propylanisole
104-45-0

4-n-propylanisole

Conditions
ConditionsYield
With potassium carbonate In 1,2-dimethoxyethane at 145℃; for 0.416667h; Microwave irradiation; Inert atmosphere; Sealed vessel;61%
O-[3-(4-meethoxyphenyl)propyl] O-phenyl thiocarbonate
1242438-12-5

O-[3-(4-meethoxyphenyl)propyl] O-phenyl thiocarbonate

4-n-propylanisole
104-45-0

4-n-propylanisole

Conditions
ConditionsYield
With di-tert-butyl peroxide; tris-(trimethylsilyl)silane In benzene at 135℃; for 2h; Barton-McCombie deoxygenation; Inert atmosphere;60%
cyclopropyl bromide
4333-56-6

cyclopropyl bromide

3-(4-methoxyphenyl)-1-iodopropane
113379-13-8

3-(4-methoxyphenyl)-1-iodopropane

A

Estragole
140-67-0

Estragole

B

4-n-propylanisole
104-45-0

4-n-propylanisole

C

1-(3-cyclopropylpropyl)-4-methoxybenzene

1-(3-cyclopropylpropyl)-4-methoxybenzene

D

E-1-(4'-methoxyphenyl)prop-1-ene
4180-23-8

E-1-(4'-methoxyphenyl)prop-1-ene

Conditions
ConditionsYield
Stage #1: cyclopropyl bromide With iodine; magnesium In 2-methyltetrahydrofuran for 1.5h; Inert atmosphere; Reflux;
Stage #2: 3-(4-methoxyphenyl)-1-iodopropane With N,N,N,N,-tetramethylethylenediamine; cobalt(II) aceylacetonate In tetrahydrofuran; 2-methyltetrahydrofuran at 0℃; for 1h; Inert atmosphere; chemoselective reaction;
A 15%
B 7%
C 45%
D 10%
Stage #1: cyclopropyl bromide With iodine; magnesium In 2-methyltetrahydrofuran for 1.5h; Inert atmosphere; Reflux;
Stage #2: 3-(4-methoxyphenyl)-1-iodopropane With cobalt(II) chloride In tetrahydrofuran; 2-methyltetrahydrofuran at 0℃; for 1h; Inert atmosphere; chemoselective reaction;
A 10%
B 13%
C 16%
D 7%
4-methoxy-trans-cinnamaldehyde
24680-50-0, 71277-11-7, 1963-36-6

4-methoxy-trans-cinnamaldehyde

A

4-n-propylanisole
104-45-0

4-n-propylanisole

B

3-(4-methoxyphenyl)propional
20401-88-1

3-(4-methoxyphenyl)propional

C

3-(p-methoxyphenyl)-1-propanol
5406-18-8

3-(p-methoxyphenyl)-1-propanol

Conditions
ConditionsYield
With methanol; formic acid; water; silica gel; palladium dichloride for 0.9h; Irradiation; microwave;A 36%
B 8%
C 44%
cyclopropyl bromide
4333-56-6

cyclopropyl bromide

3-(4-methoxyphenyl)-1-iodopropane
113379-13-8

3-(4-methoxyphenyl)-1-iodopropane

A

4-n-propylanisole
104-45-0

4-n-propylanisole

B

1-(3-cyclopropylpropyl)-4-methoxybenzene

1-(3-cyclopropylpropyl)-4-methoxybenzene

C

E-1-(4'-methoxyphenyl)prop-1-ene
4180-23-8

E-1-(4'-methoxyphenyl)prop-1-ene

Conditions
ConditionsYield
Stage #1: cyclopropyl bromide With iodine; magnesium In 2-methyltetrahydrofuran for 1.5h; Inert atmosphere; Reflux;
Stage #2: 3-(4-methoxyphenyl)-1-iodopropane With (1R,2R)-1,2,3,3-tetramethyl-1,2-cyclohexanediamine; cobalt(II) chloride In tetrahydrofuran; 2-methyltetrahydrofuran at 0℃; for 1h; Reagent/catalyst; Inert atmosphere; chemoselective reaction;
A 11%
B 42%
C 28%
1-bromo-4-methoxy-benzene
104-92-7

1-bromo-4-methoxy-benzene

isopropylmagnesium chloride
1068-55-9

isopropylmagnesium chloride

A

4-n-propylanisole
104-45-0

4-n-propylanisole

B

1-methoxy-4-(1-methylethyl)benzene
4132-48-3

1-methoxy-4-(1-methylethyl)benzene

Conditions
ConditionsYield
With N,N,N'N'-tetramethyl-1,3-propanediamine; 1,3-bis(mesityl)imidazolium chloride; cobalt(II) chloride In diethyl ether at 25℃; for 1h; Inert atmosphere;A 34%
B 9%
cyclopropyl bromide
4333-56-6

cyclopropyl bromide

3-(4-methoxyphenyl)-1-iodopropane
113379-13-8

3-(4-methoxyphenyl)-1-iodopropane

A

Estragole
140-67-0

Estragole

B

4-n-propylanisole
104-45-0

4-n-propylanisole

C

1-(3-cyclopropylpropyl)-4-methoxybenzene

1-(3-cyclopropylpropyl)-4-methoxybenzene

Conditions
ConditionsYield
Stage #1: cyclopropyl bromide With iodine; magnesium In 2-methyltetrahydrofuran for 1.5h; Inert atmosphere; Reflux;
Stage #2: 3-(4-methoxyphenyl)-1-iodopropane With iron(III) chloride; N,N,N,N,-tetramethylethylenediamine In tetrahydrofuran; 2-methyltetrahydrofuran at 0℃; for 1h; Inert atmosphere; chemoselective reaction;
A 19%
B 15%
C 32%
carbon monoxide
201230-82-2

carbon monoxide

anethole
104-46-1

anethole

A

4-(4-methoxyphenyl)butan-1-ol
52244-70-9

4-(4-methoxyphenyl)butan-1-ol

B

4-n-propylanisole
104-45-0

4-n-propylanisole

C

2-(4-Methoxy-phenyl)-butan-1-ol
55297-05-7

2-(4-Methoxy-phenyl)-butan-1-ol

Conditions
ConditionsYield
With 1-hydroxytetraphenylcyclopentadienyl(tetraphenyl-2,4-cyclopentadien-1-one)-μ-hydrotetracarbonyldiruthenium(II); dicarbonylacetylacetonatorhodium(I); tris[(R)-2’-(benzyloxy)-1,1’-binaphthyl-2-yl]phosphite; hydrogen In toluene at 120℃; under 30003 Torr; for 20h; Autoclave;A n/a
B 16%
C n/a
Estragole
140-67-0

Estragole

A

cis-Anethole
25679-28-1

cis-Anethole

B

4-n-propylanisole
104-45-0

4-n-propylanisole

C

E-1-(4'-methoxyphenyl)prop-1-ene
4180-23-8

E-1-(4'-methoxyphenyl)prop-1-ene

Conditions
ConditionsYield
With borane-ammonia complex; [Fe(nacnac)dippCH2SiMe3] In benzene-d6 at 60℃; for 16h; Inert atmosphere; Glovebox; Overall yield = 62 percent; Overall yield = 45.9 mg; Optical yield = 80.769 percent de;A n/a
B 15%
C n/a
With carbonylhydrido[6-(di-tert-butylphosphinomethylene)-2-(N,N-diethylaminomethyl)-1,6-dihydropyridine]ruthenium(II) In isopropyl alcohol at 20℃; for 16h; Inert atmosphere; Glovebox; Schlenk technique; Sealed tube;
para-iodoanisole
696-62-8

para-iodoanisole

propyl zinc chloride
98398-49-3

propyl zinc chloride

A

4-n-propylanisole
104-45-0

4-n-propylanisole

B

methoxybenzene
100-66-3

methoxybenzene

Conditions
ConditionsYield
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride In tetrahydrofuran; diethyl ether at 20℃; for 3h;A 94 % Spectr.
B 5%
4-n-butylanisole
18272-84-9

4-n-butylanisole

4-n-propylanisole
104-45-0

4-n-propylanisole

Conditions
ConditionsYield
at 310 - 320℃; im Rohr;
at 310 - 320℃; im mit Stickstoff gefuellten Rohr;
4-n-propylanisole
104-45-0

4-n-propylanisole

acetyl chloride
75-36-5

acetyl chloride

1-(2-Methoxy-5-propylphenyl)ethanone
873314-99-9

1-(2-Methoxy-5-propylphenyl)ethanone

Conditions
ConditionsYield
Stage #1: 4-n-propylanisole; acetyl chloride With aluminum (III) chloride In dichloromethane at -10℃; for 0.5h;
Stage #2: With hydrogenchloride In dichloromethane; water
100%
Stage #1: 4-n-propylanisole; acetyl chloride With aluminum (III) chloride In dichloromethane at -10℃; for 0.5h; Friedel Crafts Acylation;
Stage #2: With hydrogenchloride; water In dichloromethane at 0℃;
4-n-propylanisole
104-45-0

4-n-propylanisole

4-Methoxystyrene
637-69-4

4-Methoxystyrene

Conditions
ConditionsYield
With [CuCl(ClIPr)]; sodium t-butanolate; tert-butyl alcohol In tetrahydrofuran; hexane at 40℃; for 20h; Inert atmosphere; chemoselective reaction;99%
4-n-propylanisole
104-45-0

4-n-propylanisole

4-Methoxypropiophenone
121-97-1

4-Methoxypropiophenone

Conditions
ConditionsYield
With dipotassium peroxodisulfate; copper(I) sulfate In water; acetonitrile at 65 - 70℃; for 3h;85%
With formic acid; water; 2,3-dicyano-5,6-dichloro-p-benzoquinone In 1,4-dioxane at 110 - 120℃; for 0.266667h; microwave irradiation;66%
With Bromotrichloromethane; Ir[2-(2,4-difluorophenyl)-5-(trifluoromethyl)pyridine]2(4,4'-di-tert-butyl-2,2'-bipyridine)PF6; water; potassium carbonate In acetonitrile at 20℃; Irradiation; Inert atmosphere; regioselective reaction;60%
4-n-propylanisole
104-45-0

4-n-propylanisole

α-bromoethyl 3-bromo-4-methoxyphenyl ketone
4374-35-0

α-bromoethyl 3-bromo-4-methoxyphenyl ketone

Conditions
ConditionsYield
With N-Bromosuccinimide; water at 35 - 40℃; for 10h; Wohl-Ziegler Bromination; Irradiation;82%
1,2,3-Benzotriazole
95-14-7

1,2,3-Benzotriazole

4-n-propylanisole
104-45-0

4-n-propylanisole

1-(1-(4-methoxyphenyl)propyl)-1H-benzo[d][1,2,3]triazole
156602-61-8

1-(1-(4-methoxyphenyl)propyl)-1H-benzo[d][1,2,3]triazole

Conditions
ConditionsYield
With Bromotrichloromethane; Ir[2-(2,4-difluorophenyl)-5-(trifluoromethyl)pyridine]2(4,4'-di-tert-butyl-2,2'-bipyridine)PF6; potassium carbonate In acetonitrile at 20℃; Irradiation; Inert atmosphere; regioselective reaction;80%
4-n-propylanisole
104-45-0

4-n-propylanisole

acetic acid
64-19-7

acetic acid

1-(4-methoxyphenyl)prop-1-yl acetate
16031-55-3

1-(4-methoxyphenyl)prop-1-yl acetate

Conditions
ConditionsYield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone for 1.16667h; sonication;74%
4-n-propylanisole
104-45-0

4-n-propylanisole

4-methoxy-trans-cinnamaldehyde
24680-50-0, 71277-11-7, 1963-36-6

4-methoxy-trans-cinnamaldehyde

Conditions
ConditionsYield
With acetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone In 1,4-dioxane for 2h;72%
4-n-propylanisole
104-45-0

4-n-propylanisole

4-methoxycinnamaldehyde
1963-36-6

4-methoxycinnamaldehyde

Conditions
ConditionsYield
With acetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone In 1,4-dioxane Microwave irradiation;70%
4-n-propylanisole
104-45-0

4-n-propylanisole

A

4-methoxycinnamaldehyde
1963-36-6

4-methoxycinnamaldehyde

B

4-methoxy-trans-cinnamaldehyde
24680-50-0, 71277-11-7, 1963-36-6

4-methoxy-trans-cinnamaldehyde

Conditions
ConditionsYield
With bunazosin In 1,4-dioxaneA 68%
B n/a
4-n-propylanisole
104-45-0

4-n-propylanisole

A

4-methoxybenzoic acid
100-09-4

4-methoxybenzoic acid

B

4-Methoxypropiophenone
121-97-1

4-Methoxypropiophenone

Conditions
ConditionsYield
With 2-Iodobenzoic acid; potassium peroxomonosulfate; water In acetonitrile for 8h;A 6%
B 64%
4-n-propylanisole
104-45-0

4-n-propylanisole

5-[(oxodiphenyl-λ6-sulfaneylidene)amino]-5H-dibenzo[b,d]thiophen-5-ium trifluoromethanesulfonate

5-[(oxodiphenyl-λ6-sulfaneylidene)amino]-5H-dibenzo[b,d]thiophen-5-ium trifluoromethanesulfonate

{[1-(4-methoxyphenyl)propyl]imino}diphenyl-λ6-sulfanone

{[1-(4-methoxyphenyl)propyl]imino}diphenyl-λ6-sulfanone

Conditions
ConditionsYield
With tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; sodium hydrogencarbonate In acetonitrile at 20℃; Schlenk technique; Inert atmosphere; Molecular sieve; Irradiation;62%

p-n-PROPYL ANISOLE Chemical Properties

IUPAC Name:1-Methoxy-4-propylbenzene
Synonyms: Dihydroanethole ; Fema 2930 ; 4-Propylanisole ; 4-N-Propylanisole ; 1-Methoxy-4-propylbenzene ; Timtec-bb sbb007737 ; P-propyl anisole ; 1-Methoxy-4-propyl-benzen
CAS NO: 104-45-0
Molecular Formula:C10H14O
Molecular Weight: 150.22
Molecular Structure:
EINECS: 203-203-4
FEMA : 2930
Mol File: 104-45-0.mol
Index of Refraction: 1.49
Surface Tension: 29.8 dyne/cm
Density: 0.922 g/cm3
Flash Point: 82.3 °C
Enthalpy of Vaporization: 42.94 kJ/mol
Boiling Point: 211.4 °C at 760 mmHg
Vapour Pressure: 0.266 mmHg at 25°C
Appearance: P-N-Propyl anisole (CAS NO. 104-45-0) is colorless to pale yellow liquid.
Solubility:  P-N-Propyl anisole (CAS NO. 104-45-0) is soluble in ethanol, the majority of non-volatile oil and mineral oil, insoluble in glycerin and propylene glycol.
 

p-n-PROPYL ANISOLE Uses

  P-N-Propyl anisole (CAS NO. 104-45-0) is used as spices, mainly for the preparation of beer flavor.

p-n-PROPYL ANISOLE Production

anethole in the nickel catalyst at the 60 ~ 95 ℃ and pressure, formed under the conditions of partial hydrogenation.

p-n-PROPYL ANISOLE Toxicity Data With Reference

1.    

sln-dmg-orl 5 mmol/L

    FCTOD7    Food and Chemical Toxicology. 21 (1983),707.
2.    

orl-rat LD50:4400 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 6 (1964),378.
3.    

orl-mus LD50:7300 mg/kg

    FCTXAV    Food and Cosmetics Toxicology. 2 (1964),327.

p-n-PROPYL ANISOLE Consensus Reports

Reported in EPA TSCA Inventory.

p-n-PROPYL ANISOLE Safety Profile

Mildly toxic by ingestion. Mutation data reported. Combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes DangerousN
Risk Statements 51/53
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements 61 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
WGK Germany 2
RTECS BZ9450000
 

 

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