A novel pyrrolobenzodiazepine dimer payload, SG3227, was rationally designed based on the naturally occurring antitumour compound sibiromycin. SG3227 was synthesized from a dimeric core in an efficient fashion. An unexpected room temperature Diels-Alder reaction occurred during the final step of...

A new separation and quantification method using ultra high-performance liquid chromatography (UHPLC) with UV detection was developed for the detection of sibiromycin in fermentation broth of Streptosporangium sibiricum. The solid phase extraction method based on cation-exchange was employed to ...

Load-bearing implants are developed with a particular emphasis placed on an application of ceramic hydroxyapatite coatings in order, to enhance the bioactivity of titanium implants and to shorten the healing time. Therefore, thin, fully crystalline coatings that are, highly adhesive, hydrophilic...

Presented is a study on the mechanochemically assisted synthesis of kesterite Cu2ZnSnS4 from the elements for photovoltaic applications. Initial application of high energy ball milling under selected conditions, including the highest achievable rotation speeds up to 1000 rpm, affords a pure cubi...

In this chapter, the main attention is focused on the production of ultrafine and nanopowders and their application in the particulate condition and consolidated state. Features of nanoparticles properties, such as structural characteristics, thermodynamic data, and their mechanical, electromagn...

In this study, the corrosion inhibition of 1H-benzotriazole (BTA) alone and in combination with Na2MoO4·2H2O and Na3PO4·12H2O on single and coupled copper and mild steel in artificial sea water is evaluated. EIS and polarization results in stagnant and laminar flow conditions in different imme...

Sodium molybdate is evaluated as corrosion inhibitor for steel in brackish water; it is encapsulated by interfacial polymerization and the produced capsules are characterized. Electrochemical impedance spectroscopy and corrosion potential measurements were used to determine the short-time corros...

To limit rapid dissolution of zinc and hydrogen evolution of zinc coating in fresh concrete environments at the early stage, the corrosion inhibition of sodium molybdate for galvanized steel in simulated concrete pore solutions with/without chloride ion addition was studied. The inhibitive effec...

Tungsten is hard to be separated effectively from molybdate solution due to their extremely similar chemical properties. In this research, a novel tungsten removal method was developed to remove tungsten from the molybdate solution using nascent MnO2. Through comparing different preparation meth...

In an OECD Test Guideline 416 multigenerational study, groups of 24 male and 24 female Sprague-Dawley rats were administered sodium molybdate dihydrate at 0, 5, 17, or 40 mg molybdenum (Mo)/kg bw/day in the drinking water or 40 mg Mo/kg bw/day in the diet over two generations to assess reproduct...

The glass to crystal transformation was studied for two glasses with composition 25Na2O·50MoO3.25P2O5 and 25Na2O·50WO3.25P2O5. During the heat treatment process, two crystalline compounds were formed, NaMoO2PO4 and NaWO2PO4, respectively. Physico-chemical properties of the corresponding glasse...

A sensitive method has been proposed for the quantification of amino acids and proteins using ninhydrin and sodium molybdate as chromogenic substrates in citrate buffer of pH 5.6. A weak molybdate-hydrindantin complex plays the role in the formation of Ruhemann's purple. The linear response...

The removal of hexavalent chromium from water by sustainable methods still presents challenging aspects. Green rust (GR) is a mixed Fe(II)-Fe(III) layer double hydroxide intercalated with anions and water molecules that was recently found capable of immobilizing low concentrations of chromate. N...

In this work, the recovery of Cr from vanadium-containing chromate solution with copper salt precipitation after V separation is presented. It has been found that after V in the vanadium-containing chromate solution was separated, Cr can be effectively enriched by adding CuSO4. Cr in the solutio...

The pollution of toxic and carcinogenic chromium slags of the chromate industry has been a public concern and industrial symbiosis is proved to be feasible and efficient in recycling chromium slags. How to appraise and improve sustainability of chromate industrial symbiosis networks is still an ...

The effects of food supplementation with sodium chromate at concentrations of 1–500 μM on development of Drosophila melanogaster larvae and food intake, carbohydrate and lipid pools in adult fruit flies were investigated. Food supplementation with hexavalent chromium (Na2CrO4) at high concentr...

Chromium chemicals are made from sodium chromate, a basic intermediate product for the production of all other chromium compounds. This article presents application of the Life Cycle Assessment (LCA) methodology to choose the best method of production of sodium chromate. Three variants of sodium...

Currently, 80–90% of leather production uses chromium tanning; thus, the trimmings and shavings resulting from the manufacturing of leather goods create a waste with a high pollution potential. One alternative for handling this scrap-leather waste is thermal treatment (gasification and combusti...

In order to clean production of chromium compounds, it is a critical process to remove aluminates and utilize aluminum compounds from artificial chromate alkali solutions. The effects of Na2CrO4 on the neutralization curve, Al(OH)3 precipitation efficiency and induction period of bayerite were i...

Solubility and metastable zone width (MSZW) of aqueous sodium dichromate solutions in different concentration of sodium chromate were studied experimentally by the polythermal method using a turbidity monitoring technique. The effects of cooling rate R, saturation temperature T0 of sodium dichro...