Copolymers and block copolymers are employed widely in drug delivery applications from the development of sustained release products to smart polymeric delivery systems such as stimuli-responsive polymeric systems, for example, thermosensitive, redox-sensitive, photo-sensitive, enzyme-sensitive ...

2S albumins, the seed storage proteins, are the primary sources of carbon and nitrogen and are involved in plant defense. The mature form of Moringa oleifera (M. oleifera), a chitin binding protein isoform 3-1 (mMo-CBP3-1) a thermostable antifungal, antibacterial, flocculating 2S albumin is wide...

Electromagnetic transient (EMT) simulations are now often used for system studies including power electronics converters which control voltages and currents using switching devices. The trapezoidal method, used in Electro-Magnetic Transients Program (EMTP) for numerical integration, produces “f...

A multi-dimensional analysis of prompt charmonia in pp and pPb collisions at sNN=5.02TeV with the CMS detector is presented. The pPb differential cross-sections of prompt J/ψ are shown in a wide kinematic region, for transverse momentum pT spanning from 2 to 30 GeV/c and a rapidity interval bet...

We report the preparation of a novel glutamine derivative, (2S,4S)-2,5-diamino-4-(4-(2-fluoroethoxy)benzyl)-5-oxopentanoic acid, (2S, 4S)4-[18F]FEBGln ([18F]4), through efficient organic and radiosyntheses. In vitro assays of [18F]4 using MCF-7 cells showed that it entered cells via multiple ami...

A short partial sequence of 28 amino acids is all the information we have so far about the putative allergen 2S albumin from almond. The aim of this work was to analyze this information using mainly bioinformatics tools, in order to verify its rightness.Based on the results reported in the paper...

Members of the monothiol glutaredoxin family and members of the BolA-like protein family have recently emerged as specific interacting partners involved in iron-sulfur protein maturation and redox regulation pathways. It is known that human mitochondrial BOLA1 and BOLA3 form [2Fe-2S] cluster-bri...

The CBC3 is the latest version of the CMS Binary Chip for readout of the outer radial region of the upgraded CMS Tracker at the High Luminosity LHC. This 254-channel, 130 nm CMOS ASIC is designed to be bump-bonded to a substrate to which sensors will be wire-bonded. It will instrument double-lay...

The product of the electronic width of the ψ(2S) meson and the branching fraction of its decay to the muon pair was measured in the e+e−→ψ(2S)→μ+μ− process using nine data sets corresponding to an integrated luminosity of about 6.5 pb−1 collected with the KEDR detector at the VEPP-4M elect...

Measurements of prompt ψ(2S) meson production cross sections in proton–lead (pPb) and proton–proton (pp) collisions at a nucleon–nucleon center-of-mass energy of sNN=5.02TeV are reported. The results are based on pPb and pp data collected by the CMS experiment at the LHC, corresponding to in...

This paper presents a series of chemically modified biolubricant basestocks derived from ricinoleic acid. The reactions were monitored and products were confirmed by NMR and FTIR. The synthesis protocol is carried out in three stages: (1) epoxidation of ricinoleic acid; (2) synthesis of 10,12-di...

Ceriporiopsis subvermispora is a selective white rot basidiomycete which degrades lignin in wood at a distance far from enzymes. Low molecular mass metabolites play a central role in the oxidative degradation of lignin. To understand the unique wood-decaying mechanism, we surveyed the oxidized d...

The conversion of Undaria pinnatifida residue to glycolic acid was carried out using methylamine as catalyst by hydrothermal method at relatively low temperature. GC–MS and HPLC were used to identify the composition of bio-oil and liquid products which provide the knowledge of the chemical reac...

Enzymes are good alternative to chemical catalysts for polymer syntheses in terms of high region- and stereoselectivity and environmentally benign reaction conditions. In particular, for the synthesis of functional polymers, enzymatic process will not cause undesired reactions such as ring-openi...

Soapstock containing high value of free unsaturated fatty acids was used for enzymatic production of natural epoxides in a solvent-free system. At a same reaction condition (36 °C, initial pH of 6.5, and H2O2/CC molar ratio of 1 for 30 min), using a microchannel bioreactor were enhanced the yie...

Boron trifluoride diethyl etherate (BF3·OEt2) catalyzed ring-opening polymerization of euphorbia oil (EuO), natural epoxy oil, in liquid carbon dioxide was conducted in an effort to develop useful vegetable oil based polymers. The resulting polymers (RPEuO) were characterized by FTIR, 1H NMR, 1...

Tenatoprazole, a substituted imidazopyridinyl derivative, is an irreversible proton pump inhibitor (PPI), which is used for the prevention and treatment of gastric acid-related diseases. A new highly efficient asymmetric oxidation using cumene hydroperoxide (CHP) as the oxidant in the presence o...

In the present study, comprehensive stress testing of tenatoprazole was carried out according to ICH guideline Q1A (R2). Tenatoprazole was subjected to stress conditions of hydrolysis, oxidation, photolysis and neutral decomposition. Additionally, the solid drug was subjected to 50 °C for 60 da...

Despite the weak acidic character of tenatoprazole it is possible to crystallize, in strong alkaline media, different solvated salts of this active pharmaceutical ingredient. Among these solid phases, some potassium salts exhibiting non congruent solubilities, form stable conglomerates in equili...

Tenatoprazole is a prodrug of the proton pump inhibitor (PPI) class, which is converted to the active sulfenamide or sulfenic acid by acid in the secretory canaliculus of the stimulated parietal cell of the stomach. This active species binds to luminally accessible cysteines of the gastric H+,K+...