DES (deep eutectic solvents) are a new class of ionic liquids that have excellent properties. The strength of interaction between molecules in the DES affects their properties and applications. In this work, the strength of molecular interactions between components in the betaine monohydrate sal...

In the palm oil industry, the deacidification process is performed by steam stripping which causes the loss of most of palm oil’s natural antioxidants due to high temperature. The liquid–liquid extraction process which is carried out at low temperature is preferable in order to preserve these ...

9H-Carbazole-9-(4-phenyl) boronic acid pinacol ester (9-CPBAPE) molecule was investigated by FT-IR, Raman, UV–vis, 1H and 13C NMR spectra. FT-IR, FT-Raman and dispersive Raman spectra were recorded in the solid phase. 1H, 13C NMR and UV–vis spectra were recorded in dimethyl sulfoxide (DMSO) so...

Gangjee et al. recently reported a novel series of 2-amino-4-methyl-5-phenylethyl substituted-7-benzyl-pyrrolo[2,3-d]pyrimidines, some of which exhibited two digit nanomolar antitumor and antimitotic activity and were not subject to P-glycoprotein (Pgp) or multidrug resistance protein 1 (MRP1) m...

Further investigation of the potential anticonvulsant activity of the enaminones was attempted to discern the possible role of metabolites as the active/co-active entities of the esters of the enaminones. A series of 5-methyl-2-cyclohexene enaminones, the hypothesised metabolites corresponding t...

A combinatorial chemical library of fifty-nine novel 3-amino-1′-((1-aryl-1H-1,2,3-triazol-5-yl)methyl)-2′-oxospiro[benzo[a]pyrano[2,3-c]phenazine-1,3′-indoline]-2-carbonitrile, designed as hybrid molecules of phenazine, pyran, indole and 1,2,3-triazole pharmacophores, were constructed in this...

An efficient, convenient method for the synthesis of 3,4-dihydropyrano[3,2-c]chromene derivatives by one-pot, three-component reaction of aldehydes, malononitrile/cyanoacetate, and 4-hydroxycoumarin in the presence of a catalytic amount of thiourea dioxide, an efficient, reusable organic catalys...

The presence of foreign bodies in a prostate transurethral resection may pose a histopathological challenge. A 65-year-old white man with urinary obstructive symptoms was subjected to a transurethral resection. Histopathology showed a squamous cell carcinoma affecting prostatic ducts and multipl...

PurposeThe aims of this study were to evaluate treatment responses and predictive factors for overall survival (OS) in hepatocellular carcinoma (HCC) patients with portal vein tumor thrombosis (PVTT) treated with iodine-125 (125I) brachytherapy.

Synthesis of benzothiazoles from 2-aminobenzenethiols and carbon dioxide was carried out using poly(3,4-dimethyl-5-vinylthiazolium) iodide as a precatalyst to in situ generation of NHCs by deprotonation. The reaction was successfully carried out under mild conditions (1 atm of CO2 and 60–70 °C...

Apparent molar volumes Vϕ and apparent molar heat capacities Cp,ϕ were determined at the pressure 0.35 MPa for aqueous solutions of magnesium nitrate Mg(NO3)2 at molalities m = (0.02 to 1.0) mol · kg−1, strontium nitrate Sr(NO3)2 at m = (0.05 to 3.0) mol · kg−1, and manganese nitrate Mn(NO3)2 ...

The effect of temperature and magnetic field strength on 13C relaxation rates of gluconate and magnesium-gluconate solutions are determined at 7.0 and 11.7 Tesla. The primary component of relaxation along the gluconate backbone is dipolar in gluconate solutions with spin rotation relaxation a co...

The solubility in water of magnesium-l-ascorbate, calcium-l-ascorbate, magnesium-l-glutamate, magnesium-d-gluconate, calcium-d-gluconate, calcium-d-heptagluconate, l-aspartic acid, and 3-nitrobenzoic acid was determined in the 278.15 K to 343.15 K temperature range. The solubility of these compo...

Magnesium sulfate has been administered intravenously to arrest preterm labor but the oral form of this drug cannot be used for continual tocolysis. This trial involved the administration of oral magnesium gluconate to determine its effectiveness compared with that of ritodrine hydrochloride in ...

Considering the production of stable CAC aqueous suspensions, this work addressed the action of gluconate anion as a Ca2+ complexing agent and retarder of CAC hydration. Using quantum simulations, the complexation energy of gluconate complexes was calculated. The pH range of stability for the co...

Aqueous solutions of sodium gluconate have been studied by 1D and 2D NMR spectroscopy. 1H NMR spectra of solutions demonstrate the fact that in the concentration range from 4 to 200 mmol/l the shapes of the lines corresponding to different groups of protons do not change. The 13C NMR spectrum pr...

Magnesium gluconate is a classical organometallic pharmaceutical compound used for the prevention and treatment of hypomagnesemia as a source of magnesium ion. The present research described the in-depth study on solid state properties viz. physicochemical and thermal properties of magnesium glu...

A balanced Latin square design was used to evaluate the effectiveness and acceptability of 2 propoxyphene salts in consenting postpartum patients with pain. Attention was paid to the intensity of pain and its change on treatment, an estimate of pain relief, and the frequency and intensity of sym...

Background: The subjective, psychomotor, and physiological effects of a widely prescribed prescription opioid, propoxyphene, have not been studied in a population of non-drug-abusing people. The drug also has potential for abuse and it was of interest in the present study to determine if the dru...

One hundred and seventy eight heroin addicts entered propoxyphene napsylate (PN) maintenance. Patients attended a general medical clinic twice each week and took home a three- to four-day supply of PN, to be taken in doses of 300 to 400 mg three or four times per day. Over a 21-month period, sub...