A N-bromosuccinimide (NBS) mediated decarboxylative sulfonylation of β-keto acids with sodium sulfinates is developed. The transformation exhibits a broad substrate scope and good functional group tolerance. Preliminary mechanistic studies showed that this reaction is likely to proceed through ...
A highly stereoselective dibromination of diphenylphosphorylallenes using N-bromosuccinimide (NBS) as bromine reagent is developed, wherein a variety of 2-bromo-substituted allyl bromides were obtained in good to excellent yields under mild reaction conditions. Moreover, the dibromination reacti...
When praziquantel was exposed to N-bromosuccinimide in the presence of ethanol, a tricyclic 3-bromo-1-ethoxy pyrazinone was formed. From this and the analogous 1,3-dibromopyrazinone, a small library of 3-alkylamino-1-ethoxy, 1,3-dialkoxy, 3-alkoxy-1-bromo, and 3-alkylamino-1-bromo substituted py...
A highly efficient method for the synthesis of α-halocarbonyl compounds has been achieved via selective monobromination of aromatic and aliphatic carbonyl compounds with N-bromosuccinimide catalyzed by p-toluenesulfonic acid under microwave irradiation within 30 min.
Regioselective monobromination of various aromatics was achieved at room temperature using N-bromosuccinimide and 5 mol% of thioamides in acetonitrile. With thiourea as catalyst, activated aromatics, such as anisole, acetanilide, benzamide and phenol analogues containing electron donating or wit...
A new postchemiluminescence (PCL) reaction was observed when urea was injected into the reaction mixture after the CL reaction of N-bromosuccinimide and dichlorofluorescein. A possible reaction mechanism was proposed based on the studies of the CL kinetic characteristics, CL spectra, fluorescenc...
A new synthetic method for triazatruxenes from indoles is developed using N-bromosuccinimide (NBS) as a user-friendly reagent. Major reaction parameters including the amount of NBS, substrate concentration, temperature, addition rate and addition method are investigated. Additional experiments a...
A facile transformation of alkynes into α-amino ketones by an N-bromosuccinimide-mediated one-pot cascade strategy is described. A variety of α-amino ketones are obtained in moderate to good yields under mild conditions. To overcome the multi-step synthesis, N-bromosuccinimide is involved in m...
The bromination of unsymmetrical indodicarbocyanine dyes bearing electron-donating groups (–NHCOCH3, –OH) on the aryl rings using N-bromosuccinimide produces dimeric molecules together with the corresponding meso-brominated dyes. The direction of the process depends on the reaction conditions....
The primary ecological risk of dimethyldithiocarbamate (DMDC), a dithiocarbamate fungicide (DTC) metabolite, was evaluated based on their probabilistic environmental concentration distributions (ECDs) in the coastal environment, Hiroshima Bay, Japan. And their behavior and temporal trends was fu...
Dithiocarbamates, acting as inhibitors of catecholamine synthesis, have been reported to block ovulation in female rats following systemic administration by suppressing the neural noradrenergic signaling involved in triggering the ovulatory surge of luteinizing hormone. The ovaries also synthesi...
The determination of specific anionic species (sodium dimethyldithiocarbamate) in waste water was performed by capillary electrophoresis with direct UV detection. The application of new technology sulfonic acid polymer-coated capillary columns achieved sensitive analysis with robust electroosmot...
The primary etiology of Parkinson’s disease (PD) remains unclear, but likely reflects a combination of genetic and environmental factors. Exposure to some pesticides, including ziram (zinc dimethyldithiocarbamate), is a relevant risk factor for PD. Like some other environmental neurotoxicants, ...
Sodium dimethyldithiocarbamate (SDMC) has been used in a variety of pesticidal applications as insecticide, fungicide, miticide, and microbicide. The dithiocarbamates (DCs) are basically cytotoxic and regarded as broad-spectrum biocides. The DCs are the half amides of dithiocarbamic acid. They h...
Ferric dimethyldithiocarbamate (ferbam) and bis(dimethylthiocarbamoyl) disulfide (thiram) are agriculturally important fungicides. The effect of these compounds on development was studied during gametogenesis in rats, organogenesis in rats and mice, and the peri- and postnatal period in rats. Fe...
These studies were conducted to identify the P450 isozymes participating in the metabolism of thiram (tetramethylthiuram disulfide) and its two metabolites DMDC (dimethyldithiocarbamate) and CS2 (carbon disulfide), and to establish the relationship between the P450-mediated metabolism of these c...
A spectrophotometric method was developed for the determination of ferbam (iron(III) dimethyldithiocarbamate) by converting it into an iron-phenanthroline complex, which was then absorbed on microcystalline naphthalene in the presence of tetraphenylborate, and the absorbance was measured at 515 ...
N,N-Dimethyldithiocarbamate (DMDTC) is a typical precursor of N-nitrosodimethylamine (NDMA). Based on separate hydrolysis, sorption and biodegradation studies of DMDTC, a laboratory-scale anaerobic-anoxic-oxic (AAO) system was established to investigate the removal mechanism of DMDTC in this nut...
Treatment of rats and mice with a single oral dose of dimethyldithiocarbamate (DMDTC; 250 mg/kg) had a marked effect on hepatic CYP2E1 and aldehyde dehydrogenase activities, measured in vitro, for up to 24 h after dosing. The same treatment did not affect CYP2A6, glutathione S-transferase, epoxi...
The aim of this study was to evaluate the resistance of Rhamdia quelen (silver catfish) to Aeromonas hydrophila infection after treatment with pure and nanoencapsulated forms either terpinen-4-ol, thymol, or carvacrol and the effects of these treatments on fish metabolic responses. After A. hydr...
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View