The activation of 3,5-dinitrobenzoic acid (3,5-DNBA) in situ is proposed for electrocatalytic detection of NADH at low overpotentials. Thus, 3,5-DNBA was strategically connected to a nanostructured surface based on MWCNTs and PEI (an amine rich polymer). Then, R–NO/R–NHOH was electrogenerated ...

New methods for the synthesis of (E)-3-halo-2-styryl-4H-chromen-4-ones were established. The reaction of these compounds with hydrazine hydrate afforded new and unexpected 3(5)-aryl-5(3)-[2-(2-hydroxyphenyl)-2-hydrazonoethyl]-1H-pyrazoles, which upon acid hydrolysis gave 3(5)-aryl-5(3)-[2-(2-hyd...

The structures of 2-nitramino-3-nitropyridine and 2-nitramino-5-nitropyridine have been characterized by X-ray diffraction and Density Functional Theory (DFT) studies. In the crystals, both compounds exist as the imino forms. The DFT calculations were performed in order to explore the amino-imin...

1We report a new strategy to synthesize hybrid fluorescent nanosensors consisting of phenylboronic acid-functionalized POSS (POSS–PBA) and diol-modified 8-anilino-1-naphthalenesulfonic acid (ANSA (a fluorescent dye)) for the detection of the biologically important d-glucose. The probe was chara...

A series of some new quinazolinone based MCT reactive dyes (7a–j) were successfully and easily synthesized by the coupling route of diazotized 3-{4-[4-amino-2, 6-difluorobenzyl]-3,5-difluorophenyl}-6-nitro-2-phenylquinazolin-4(3H)-one (4) with a diverse range of o-chloro-p-nitro anilino cyanura...

The influence of catalysts on the addition of methoxy- and fluoroanilines with 1,4-naphthoquinone to give methoxy- and fluoro-substituted 2-(anilino)-1,4-naphthoquinones was investigated. In the absence of a catalyst, this reaction requires long times and low yields of the anilino derivatives ar...

Heterocyclic amines were diazotized and coupled with 8-anilinonaphthalene-1-sulfonic acid magnesium salt to synthesize some new heterocyclic monoazo dyes, showing ammonium-azonium tautomerism. The structures of the dyes were characterized by 1H‐NMR, MALDI, FTIR, and UV–Visible spectroscopy. Th...

A new type of carbohydrate-derived pyridinecarboxylic organocatalyst was prepared by fine-tuning a d-glucosamine backbone at the C-2 and C-3 positions. The carbohydrate-derived pyridinecarboxylic organocatalyst was used for the enantioselective reduction of imines with trichlorosilane. The reduc...

The current study deals with the synthesis of urea and thiourea derivatives 1–37 which were characterized by various spectroscopic techniques including FAB-MS, 1H-, and 13C NMR. The synthetic compounds were subjected to urease inhibitory activity and compounds exhibited good to moderate urease ...

Crystals of N-(3,5-diXsalicylidene)-2-methoxyaniline (X = fluoro, chloro, bromo, and iodo) were prepared, and their structural and luminescence properties in the solid state were investigated. Only fluorescent orange crystals were obtained for N-(3,5-difluorosalicylidene)-2-methoxyaniline (1). B...

-Exogenously supplied 4-hydroxybenzoic acid (HBA) was converted quantitatively to 4-(β-d-glucopyranosyloxy) benzoic acid (HBA glucoside) during 30 hr of germination of the pollen of Pinus densiflora (pine pollen). [14C-carboxyl]HBA ([14C]-HBA) was also converted to [14C]-HBA glucoside by pine p...

This research communication is toward the investigation of the antibacterial, antifungal and antioxidant activities of the synthesized compounds 1-(4′-O-β-d-glucopyranosyloxy-2′-hydroxyphenyl)-3-aryl-propane-1,3-diones (5a)–(5h). These compounds have been obtained by the interaction of α-ac...

The host-guest chemistry of the anthocyanin analog 7-β-D-glucopyranosyloxy-4′-hydroxyflavylium (GHF) was studied in the presence of the β-cyclodextrin derivative captisol by stopped flow, UV–visible spectroscopy, flash photolysis, circular dichroism and isothermal titration calorimetry. The ...

Z-2-(β-d-glucopyranosyloxy)-3-phenylpropenoic acid (PPAG), a compound postulated to contribute to the taste and mouthfeel of fermented rooibos tea (Aspalathus linearis), was isolated from unfermented rooibos plant material. Its structure was unequivocally confirmed by LC–MS, –MS2, FT-IR and N...

The genotoxic activity of a new antitumor agent, FK973, was compared with that of mitomycin C (MMC) in eukaryotic and prokaryotic cells. In chromosome aberration tests using Chinese hamster fibroblast Don cells, FK973 induced a dose-related increase of aberrant cells after 6 h-pulse treatments, ...

Iododesethyl tamoxifen aziridine (I-Tam-Az), an analog of the estrogen receptor-affinity label tamoxifen aziridine (Tam-Az) in which the ethyl group has been replaced by an iodine, has been prepared by two routes: (a) metallation of a bromotriarylethylene system, followed by reaction with iodine...

Membrane-active antitumour ether lipids such as ET18-OMe (1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine) and SRI 62–834 ((±)-2-{Hydroxy[tetrahydro-2-(octadecyloxy) methylfuran-2-yl] methoxyl phosphinyloxy}-N, N, N-trimethylethaniminium hydroxide) are selectively cytotoxic to tumour cel...

Reaction of 7-amino-9-ethylguaninium chloride with lead(IV) acetate (LTA) in MeOH yielded 8-aza-9-ethylguanine. Similarly, the reaction of 1-amino-3-methylbenzimidazolium chloride or its substituted derivatives (6-methyl, 5,6-dimethyl and 5-nitro) with LTA gave the corresponding 1-methyl-1H-benz...

Accurate and precise determination of the redox state of iron (Fe) in spinels presents a significant challenge due to their refractory nature. The resultant extreme conditions needed to obtain complete dissolution generally oxidize some of the Fe(II) initially present and thus prevent the use of...

The optimization of the synthesis of Fe/N/G catalysts for the oxygen reduction reaction (ORR) has been investigated. The synthesis of Fe/N/G comprises a solid state reaction of the precursors in a planetary ballmilling followed by a thermal treatment in ammonia/nitrogen atmosphere. First, the in...