Two volatile alkaloids, methyl (MMA) and isopropyl N-methylanthranilates (IMA), identified in the essential oil of Choisya ternata Kunth (Rutaceae), have been proven to possess polypharmacological properties (antinociceptive, anti-inflammatory, gastro-, hepato-, nephroprotective activities, anxi...

The fluorescence properties of 4′-diethylamino-3-hydroxyflavone (FET), a dye probe sensitive to the polarity as well as the hydrogen bonding ability of its environment, have been studied in acetone-water mixtures by measuring spectra and decay curves over the whole composition range and analyzi...

A novel soluble functional polyacetylene copolymer (poly(EAAB-co-PA)) of 4-ethynyl-4′-[N,N-diethylamino]azobenzene (EAAB) and phenylacetylene (PA) was synthesized. The structures and properties of the polymers were characterized and evaluated by FTIR, UV–vis, 1H NMR, GPC, optical limiting, and...

The standard (p° = 0.1 MPa) molar enthalpies of formation, at T = 298.15 K, in the gaseous phase, for two nitrobenzofurazan derivatives, 4-N,N-dimethylamino-7-nitrobenzofurazan (DMANBF) and 4-N,N-diethylamino-7-nitrobenzofurazan (DEANBF), were derived from their enthalpies of combustion and sub...

Excitation wavelength dependence of photo-induced intramolecular excited state proton transfer reaction of 4′-N,N-diethylamino-3-hydroxyflavone in various liquids has been investigated by steady-state and time-resolved fluorescence measurements. It was found that the relative fluorescence inten...

The present study aims to analyze the carbon dioxide absorption process in a chemical solvent based on 2-(ethylamino)ethanol, which is not commonly used in industry for this purpose, but it allows extracting interesting conclusions about the influence of absorption regime, physical properties or...

Novel polymeric complexes with a potentially bidentate ligand N-[β-(ethylamino)] acrylamide (EA), formed by amidation of 1,2-diaminoethane with acryloyl chloride were synthesized and characterized on the basis of elemental analyses, IR, 1H NMR, UV–Vis, magnetic susceptibility measurements, ESR...

The hydrolysis and self-condensation reactions of 3-(2-amino-ethylamino)propyl-trimethoxy silane have been studied by means FT-IR spectroscopy for different water and ethanol concentrations. The hydrolysis of 3-(2-amino-ethylamino)propyl-trimethoxy silane occurs at a high rate and depends if the...

Effective photosensitizers are particularly important factor in clinical photodynamic therapy (PDT). However, there is a scarcity of photosensitizers for simultaneous cancer photo-diagnosis and targeted PDT. Herein, two novel dimethyl 2-(guanidinyl)ethylamino chlorin e6 photosensitizers were syn...

Physical N2O solubility in pure 2-(ethylamino)ethanol (EAE) solvent was measured over the temperature range 289.6– 349.7 K. The physical solubility of CO2 in EAE was then derived via the “N2O analogy” method. The effect of structural characteristics such as carbon chain length, hydroxyl group...

Cycloaddition of 3-methoxyestra-1,3,5(10),14,16-pentaen-17-yl acetate 1 with methyl propiolate, followed by chemoselective modification of the cycloadduct, furnishes intermediates for reduction-oxidative cleavage reaction sequences, leading to the 14β-formyl analogue of estrone and related 14β...

Hydroboration of 5α-cholest-8-ene, 5α, 14β-cholest-8-ene and 5α, 14β-cholest-7-ene provides a simple route to oxygenated steroids with 14β- and 8α, 14β- unnatural stereochemistry.

From leaves of Jaborosa bergii five new withanolides were isolated and studied by spectroscopic (1H and 13C NMR, MS) and chemical methods. The new products were characterized as the epoxylactol and epoxylactone derivatives of 27-deoxy-2,3-dihydrojaborosalactone A having hydroxyl groups at C-14β...

3-Trimethylsilylpropen-1-yl group, as hydroxypropenyl synthons, was easily introduced to several epoxides with the corresponding Grignard reagent derived from 3-bromoallyltrimethylsilane. The introduced skeleton of allyltrimethylsilane was regiospecifically converted to 3-hydroxy-propen-3-yl or ...

α-Chloro-βγ-unsaturated ketone (2) was synthesized from the reaction of 3-chloroallyltrimethylsilane (1) with acid chloride. The ketone was converted into αβ-unsaturated epoxide (3) regioselectively in good yield via reduction with NaBH4 or LiAlH4 followed by treatment with NaOH. Treatment ...

Water-soluble peptide-chitosans were obtained by reaction of low-molecular-weight chitosan, having a low degree of acetylation, with peptide substituents under mild conditions. These peptide substituents were prepared by standard peptide chemistry from 3-bromopropanoic acid and tert-butyl esters...

N,O-Bis(trimethylsilyl) sulphamate, Me3SiNHSO3SiMe3, has been prepared via a new, more convenient route. It is a very efficient silyl donor; more efficient under our conditions than N,O-bis(trimethylsilyl) acetamide.

PurposeIncreased 16 α-hydroxyestrone (16 α-OHE1) and autoantibodies against histone H1 (H1) have been well described in systemic lupus erythematosus (SLE), but the combination effects of 16 α-OHE1 and H1 remains unclear. Here, we tried to assess the affinity and binding specificity of SLE aut...

Racemic 1,1′-methylene[(1RS,1′RS,3RS,3′RS,5RS,5′RS)-8-oxabicyclo[3.2.1]oct-6-en-3-ol] ((±)-6) derived from 2,2′-methylenedifuran has been resolved kinetically with Candida cyclindracea lipase-catalysed transesterification giving 1,1′-methylenedi[(1R,1′R,3R,3′R,5R,5′R)-8-oxabicyclo[3.2....

A series of novel 1,2-benzothiazine 1,1-dioxide-3-ethanone oxime N-aryl acetamide ether derivatives 7a–h and 9a–h were synthesized starting from sodium salt of saccharin 1 in series of steps. Final compounds 7a–h and 9a–h were evaluated for the anti-inflammatory activity and their ability to...