Lead (II) phthalocyanine (PbPc); lead (II) tetranitro phthalocyanine (PbTNP) and lead (II) tetraamino phthalocyanine (PbTAP) are synthesized in pure state. These complexes are characterized using elemental analysis, UV–visible, IR-spectroscopy, X-ray crystallography and thermogravimetry. Kineti...

Perovskite compound-based solar cells using metal free phthalocyanine, silicon phthalocyanine or germanium naphthalocyanine complexes were fabricated and characterized for improving the photovoltaic performance. Additive effects of metal free phthalocyanine, silicon phthalocyanine or germanium n...

We developed a lead (II) phthalocyanine (PbPc)-based inverted organic photodetector (OPD) detecting near-infrared (NIR) wavelength near 940 nm. Such inverted OPDs can be combined with n-channel silicon-based integrated circuits. Operation near 940 nm is crucial in terms of daylight applications ...

In this study the synthesis and characterization of novel phthalonitrile compound (3) and its metal-free (4), zinc(II) (5), and lead(II) (6) phthalocyanines bearing four 4-(4-methoxyphenylethyl)-5-propyl-2,4-dihydro-3H-1,2,4-triazol-3-one groups at peripheral positions were synthesized for the f...

The inhibiting action of t-cinnamaldehyde (TCA) and some of its structure-related derivatives, against corrosion of ARMCO iron in 4 M HCl, has been studied, in the temperature range between 40 and 90°C. Other than TCA, α-chlorocinnamaldehyde (αCl), α-bromocinnamaldehyde (αBr), cinnamyl alco...

A study of N-thiocarbamoyl-N′-carbamoyl hydrazine derivatives as complexing ligands and their Ni, Cu, Zn and Cd complexes is described. The metals form 1:1 chelates with the ligands. One compound with formula Cu(I) (C3H5·NH·CS·NH·NH·CO·NH2)2Cl is also described. Ultraviolet and i.r. spect...

Two new mixed ligand complexes, [Cu(en)2](4-hpythol)2·2H2O (4-hpythol = 5-(4-hydroxy-phenyl)-1,3,4-thiadiazole-2-thiol) (2) and [Cu(en)2(5-thot)2] (5-thot = 5-thiophen-2-yl-3H-1,3,4-oxadiazole-2-thione (3), have been prepared, containing en as the co-ligand. The starting ligands, potassium salt...

Cu(II), Fe(III), and Mn(II) complexes of a novel ligand N′-[(4-methoxy)thiobenzoyl]benzoic acid hydrazide (H2mtbh) have been synthesized and characterized by elemental analyses, IR, UV–vis, NMR, mass, EPR and Mössbauer spectroscopy. The results suggest a square planar structure for [Cu(Hmtbh)C...

The reaction of thiobenzoyl isocyanate with hydrazines is reported. With hydrazine hydrate, 4H-5-phenyl-1,2,4-triazole-3(2H)-one was obtained in a good yield. In the reaction with mono-substituted phenylhydrazines, 2,3-dihydro-2-aryl-5-phenyl-1,2,4-triazole-3(1H)-one or 3-hydroxy-1-aryl-5-phenyl...

The hydrolysis kinetics and enzymatic cleavage of various N-acyl and N-alkoxycarbonyl derivatives of benzamide, N- methylbenzamide and salicylamide, used as models for the carboxamide group, were studied to assess their suitability as prodrugs for the amide group occurring in various drug substa...

3-Hydroxymethyl-2,3-dihydro-4H-1,3-benzoxazin-4-one and a number of its perhydrogenated derivatives were prepared from the corresponding 2-hydroxycarboxamides by treatment with a formaldehyde/formic acid mixture. Thermal decomposition of the 3-hydroxymethyl derivatives led to the previously unkn...

Poly (ethylene glycol)s (PEGs) are potential drug carriers for improving the therapeutic index of anticancer agents. In this work, a novel methodology for constructing PEG prodrug of anthracycline anticancer drugs was developed based on N-Mannich base of salicylamide and its 2-acyloxymethylated ...

The kinetics of decomposition of various N-Mannich bases of salicylamide in aqueous solution at 37°C was studied to assess their suitability as pro-drugs for amino compounds. The decomposition, yielding salicylamide, amine and formaldehyde in stoichiometric amounts, showed bell-shaped pH-rate p...

Due to their rapid cleavage at physiological pH salicylamide N-Mannich bases have been suggested as prodrug forms for primary and secondary amines. A drawback of the Mannich bases is, on the other hand, their limited stability in vitro, raising some stability-formulation problems. In the present...

Lanthanum chloranilate complex has been synthesized and characterized using different techniques like Infrared spectroscopy and CHN analysis. It has been used for the development of spectrophotometric method of determination of anions like fluoride, EDTA and iodate. The determination is based on...

Flow-injection analysis was applied to the determination of sulphate in natural water. The sample plug in the carrier stream (0.5% agueous ammonium chloride containing 50% ethanol) passes through two columns in series. The first column is packed with cation-exchange resin (ammonium form) to remo...

This paper discusses the invariability of the total ribonucleic acid of E. coli (Strain B and a lysine auxotroph), both with respect to the proportions of constituent nucleotides and to the anabolic history of the polymer, synthesized in the presence or absence of a single nucleoside acting as p...

Publisher SummaryThis chapter discusses the chemistry of nucleic acids. Yeast is the chief source of ribosenucleic acid, one of the simplest methods of isolation consists in adding, grinding an aqueous solution of potassium hydroxide to a thick paste of pressed yeast till faintly alkaline to lit...

Publisher SummaryThe nucleic acids comprise compounds that conform to the “nucleotide” pattern, consisting of a phosphoric ester of a N-l-deoxyglycoside; many of these compounds possess well-defined, coenzyme functions. In a narrower sense, the term is applied to polynucleotides, characterized...

A compilation of crystal structure data on deoxyribo- and ribonucleosides and their higher derivatives is presented. The aim of this paper is to highlight the flexibility of deoxyribose and ribose rings. So far, the conformational parameters of nucleic acids constituents of ribose and deoxyribos...