This article reports the synthesis of TiO2 nanotube arrays (TiO2 NTs), grown by Ti anodization, and their use as photoanode in a hybrid photelectrocatalytic (PEC)/photoelectro-Fenton (PEF) treatment of Indigo Carmine solutions in sulfate medium at pH 3.0. The anode was combined with an air-diffu...

A new DTTA-appended 4-(4-methoxyphenyl)-2,2′-bipyridine ligand has been synthesized for lanthanide cations by Kröhnke method. Its luminescent lanthanide (Eu3+ and Tb3+) water-soluble complexes have been synthesized. The photophysical properties of new chelates were studied. Comparison of the ne...

A new molecule of pyridylpyrazole amide (PPA) was successfully synthesized and systematically characterized by using NMR, ESI-MS and absorption (FT-IR and UV–Vis) spectroscopic techniques. The UV–Vis spectral absorption and infrared frequencies were theoretically calculated and compared with o...

t-3-Ethyl-r-2,c-6-bis(4-methoxyphenyl)piperidin-4-one (1) and its N-phenylcarbamoyl, N-acetyl and N-chloroacetyl derivatives 2–4, respectively have been synthesized and characterized using IR, 1H, 13C, DEPT-135 & 2D NMR and mass spectral studies. The NMR spectral data indicate that the N-acyl-r...

High acid crudes contain large amounts of naphthenic acids (NAs), which lead to severe corrosion in oil refinery equipment and serious environmental problems. The goal of this study is to develop a non-catalytic supercritical methanol (scMeOH) route for effective deacidification of NA mixtures a...

Glutathione S-transferase pi (GSTpi) is a phase II enzyme which protects cells from death and detoxifies chemotherapeutic agents in cancer cells. Ethacrynic acid (EA) is a weak GSTpi inhibitor. Structure modifications were done to improve the ability of EA to inhibit GSTpi activity. Eighteen EA ...

The title compounds 3a–l have been synthesized by the reaction of thiocarbohydrazide with substituted phenoxy acetic acid to obtained substituted 1,2,4-triazoles (1). Compound 1 was treated with various substituted aromatic aldehydes which results in 4-(substituted benzylideneamino)-5-(substitu...

In-depth study of structure-based drug designing can provide vital leads for the development of novel, clinically active molecules. In this present study, twenty six novel pyrazolo[1,5-a]pyrimidine analogues (6a-6z) were designed using molecular docking studies. The designed molecules were synth...

The crystalline structure of five 3-(R3) and/or 5-(R5)-substituted 7-trichloromethyl-2-methylpyrazolo[1,5-a]pyrimidines [where R3, R5 = H, Pr (1); Br, H (2); Br, Me (3); H, H (4); and H, Me (5)] were studied from X-ray diffractometry data. It was found that compounds presented themselves as main...

Condensation of 3-amino-5-hydroxypyrazole 1 with triacetic acid lactone 2 in refluxed alcohols afforded 2-hydroxy-5,7-dimethylpyrazolo〚1,5-a〛pyrimidine 3 beside to 7-alkoxycarbonylmethyl-2-hydroxy-5- methylpyrazolo〚1,5-a〛pyrimidine 4. Action of hydrazine on compounds 4 yielded 7-hydrazinocarbony...

The benzo[d]thiazol-2-yl(piperazin-1-yl)methanones scaffold has been identified as new anti-mycobacterial chemotypes. Thirty-six structurally diverse benzo[d]thiazole-2-carboxamides have been prepared and subjected to assessment of their potential anti-tubercular activity through in vitro testin...

Publisher SummaryThis chapter explains the nomenclature, synthesis, methods of analysis, and pharmacology of pirenzepine dihydrochloride. Pirenzepine is a tricyclic compound, but its physico-chemical properties differ considerably from those of other tricyclic compounds that are used as centrall...

SummaryInduction of tyrosine aminotransferase by glucocorticoid in rat hepatocytes was inhibited concentration-dependently by 1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride (H-7), an inhibitor of protein kinase C, but not by N-[2-(methylamino)-ethyl]-5-isoquinolinesulfonamide dihy...

HL-60 promyelocytic leukemia cells were induced to differentiate by 1,25-dihydroxyvitamin D3 (calcitriol) into mature monocytes. Differentiation was assessed by nitro blue tetrazolium dye reduction, nonspecific esterase activity, and DNA synthesis. Terminal differentiation of cultures induced by...

Phorbol 12-myristate 13-acetate (PMA) induces the cytolytic T lymphocyte (CTL) clone 4D (H-2b anti-H-2d) to promiscuously kill the inappropriate target EL-4 (H-2b). The protein kinase C (PKC) inhibitor 1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride (H-7) inhibited the PMA-induced ...

In this study, polymeric hydrogels derived from 3-sulfopropyl methacrylate (SPM) were used in the preparation of composite-catalyst system in hydrogen generation from hydrolysis of NaBH4. In order to generate pores and determine their effect on hydrogen production, silica based p(SPM) hydrogels ...

Poly(3-sulfopropyl methacrylate) (p(SPM)) cryogel was prepared under cryogenic conditions (T = −18 °C) and used as template for in situ metal nanoparticle preparation of Co, Ni and Cu. These metal nanoparticle-containing super macroporous cryogel composites were tested for H2 production from hy...

A novel pH-sensitive polystyrene (PS)-type resin was developed by grafting of poly(3-sulfopropyl methacrylate) (PSPMA) brushes onto a cross-linked poly(vinylbenzyl chloride) (PVBC) microsphere via surface-initiated atom transfer radical polymerization (ATRP), and was further utilized as a highly...

Poly(vinyl chloride) (PVC) was grafted with 3-sulfopropyl methacrylate potassium salt via atom transfer radical polymerization (ATRP) to produce a poly(vinyl chloride)-g-poly(3-sulfopropyl methacrylate) (PVC-g-PSPMA) amphiphilic graft copolymer, as characterized via Fourier transform infrared sp...

The complexes [Ta(OCH3)4(L)] (1,2) [where HL=2,2,6,6-tetramethylheptane-3,5-dione (tmhdH) or 2,4-pentanedione (acacH)] have been isolated from the reaction of tantalum penta-methoxide with HL in n-hexane. These complexes are relatively stable and do not fume with moist air. The solid state struc...