Copper(II) complexes have been prepared with 2-amino-4-picoline N-oxide (2am4PicO) employing the perchlorate, tetrafluoroborate, chloride and bromide salts. Preparative molar nations of 4:1 and 2:1 ligand to Cu(II) salt yielded solids having the following empirical formulas: Cu(2am4PicO)4X2 (X =...

Charge transfer complex formation between 2-amino-4-picoline (2A4P) as the electron donor with chloranilic acid (CLA) as the electron acceptor has been studied spectrophotometrically in different polar solvents included acetone (AcN), ethanol (EtOH) and acetonitrile (AN). The molecular compositi...

The three-component reaction of ethyl glyoxalate, 2-aminopyridines, and cyclic 1,3-dicarbonyl compounds such as 4-hydroxycoumarin, N,N-dimethylbarbituric acid and 4-hydroxy-6-methyl-2H-pyran-2-one is described for the synthesis of 3-hydroxyimidazo[1,2-a]pyridine zwitterion derivatives.

Five Ag(I) coordination complexes, namely, [Ag6(2-stp)2(3-methyl-2-apy)3·H2O]n (1), [Ag3(2-stp)(4-methyl-2-apy)3]n (2), [Na2Ag18(2-stp)4(2-Hstp)4(5-methyl-2-apy)16 (H2O)4·11H2O]n (3), Ag3(2-stp)(6-methy-2-apy)4·H2O (4), and [Ag6(2-stp)2(6-methyl-2-apy)8(H2O)2·H2O]n (5) (2-NaH2stp = 2-sulfote...

In this work, we report the design and synthesis of two 1D-coordination polymers under ambient condition namely {[H2-apy]2[Cu(pyzdc)2]}n (1) and {[Hbmpa]2[Cu(pyzdc)2]·2H2O}n (2), which have been prepared by the reaction between CuCl2·2H2O, 1,4-pyrazine-2,3-dicarboxylic acid (H2pyzdc) and 2-ami...

The effect of 4-aminopyridine (4AP) and 4-methyl-2-aminopyridine (4M2AP), 10−3 M, was studied on isolated spontaneously beating right atria and electrically driven left atria of the rabbit and the cat. In the rabbit preparations, 4AP had a positive inotropic effect which was unaffected by propra...

Publisher SummaryThis chapter discusses a study to analyze differences in actions of 4-aminopyridine (4AP) and 4-methyl-2-aminopyridine (4M2AP). Studies mainly with 4M2AP led von Haxthausen (1955) to conclude that aminopyridines had sympathomimetic effects. While 4M2AP shares convulsant and othe...

1.The effects of 4-methyl-2-aminopyridine (4M2AP) and 4-aminopyridine (4AP) on spontaneous and evoked [3H]-noradrenaline overflow were compared in rabbit ear artery strips. The effects of 4M2AP on smooth muscle contractility were also investigated in isolated perfused ear arteries.2.Both 4M2AP a...

1,1,1-ethanetriacetonitrile 1a, a new symmetrical tridentate ligand has been prepared from 3-methylpentenedioic acid diethylester. 6-Substituted-4-methyl-2-aminopyridines were obtained through organometallic additions on 1a.

4-Methyl-2-aminopyridine (4M2AP) increased responses of isolated rat diaphragm and chick biventer cervicis nerve-muscle preparations to nerve stimulation but depressed responses to direct stimulation. Responses to acetylcholine were also increased while responses to carbachol were depressed. Whe...

The product and the oxidative polycondensation reaction conditions of oligo-4-aminopyridine were studied by using NaOCl as oxidant. Oligo-4-aminopyridine (4-OAP) was synthesized from the oxidative polycondensation of 4-aminopyridine (4-AP) in an aqueous solution medium acidic and neutral between...

The Fourier transform infrared (FT-IR) and FT-Raman spectra of N,N-dimethyl-3-phenyl-3-pyridin-2-yl-propan-1-amine have been recorded in the range 4000–500 cm−1 and 4000–50 cm−1 respectively. The complete vibrational assignment and analysis of the fundamental modes of the compound were carried...

Novel acid mono azo and mordent acid mono azo dyes were synthesized by the coupling of diazonium salt solution of different aromatic amines with 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid. The resulting dyes were characterized by spectral techniques like elemental analysis, IR, 1H-NMR and U...

A number of fused 4-oxo-1,3-diazabicyclo[4.1.0]heptane-6-carboxylates, a new type of compound, have been obtained by Diels–Alder cycloaddition between nucleophilic 2-azadienes and an electrophilic 2H-azirine. The reactions are completely endo- and regioselective, the azirine being added by its ...

In the 2-phenylindole system, the side chain at the nitrogen atom dominates the endocrine profile both in respect to the reduction of estrogenic action and the increase of antiestrogenic potency. In previous papers we reported on 2-phenylindoles with aliphatic side chains and various functional ...

Novel crystalline actinide materials can be used to immobilize uranium and transuranium elements at radioactive waste disposal sites. However, the stability and dissolution of such phases are still poorly understood. In this study, we investigated the dissolution kinetics of two uranyl borates a...

Uranyl phosphate solids are often found with uranium ores, and their low solubility makes them promising target phases for in situ remediation of uranium-contaminated subsurface environments. The products and solubility of uranium(VI) precipitated with phosphate can be affected by the pH, dissol...

Fluoride, of all inorganic substances, is among the least likely to be identified by a routine toxicological analysis. Acute poisonings with salts of hydrofluoric or fluorosilicic acid, however, although relatively uncommon, may occur. Some fluorosilicates, salts of fluorosilicic acid (e.g. Al, ...

New cytotoxic, mononuclear Pt and Pd coordination complexes featuring the planar, multi-donor ligand (2,3-f)pyrazino(1,10)phenanthroline-2,3-dicarboxylic acid (H2PPDA) have been synthesized under hydrothermal conditions (in water, at high temperature and pressure) and fully characterized. The co...

The fac-[Re(CO)3Cl(Cl2phen)] and fac-[Re(CO)3(py)(Cl2phen)]PF6 complexes were synthesized, purified and characterized by 1H NMR, UV–Vis and IR spectroscopies and both photophysical and electrochemical behaviors were investigated. The electronic absorption spectra exhibit two main absorption ban...