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JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

Ethyl Cyanoacetate

Cas:105-56-6

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product s

Ethyl cyanoacetate Manufacturer/High quality/Best price/In stock

Cas:105-56-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Ethylcyanoacetate supplier in China

Cas:105-56-6

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Jinan Finer Chemical Co., Ltd

Product Description Product name Ethyl cyanoacetate CAS 105-56-6 Assay 99% Appearance Colorless transparent liquid Capacity 500mt/year Min.package 100gram Standard

Ethyl cyanoacetate

Cas:105-56-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

Factory supply N-Octyl Cyanoacetate

Cas:105-56-6

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Manufacturers

inquiry

Hefei TNJ chemical industry co.,ltd

Superiority Service we can provide: 1. Mixed container: We can mix different items in one container. 2. Quality control: Before shipment, we can provide free sample for test. Inspection before shipping. 3. Packing: We can pack according to y

Good quality Ethyl cyanoacetate//105-56-6

Cas:105-56-6

Min.Order:1 Metric Ton

Negotiable

Type:Trading Company

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Ethylcyanoacetate

Cas:105-56-6

Min.Order:1

Negotiable

Type:Other

inquiry

EAST CHEMSOURCES LIMITED

This product is an intermediate of fine chemical products such as medicines and dyes, and is used to synthesize esters, amides, acids and nitriles. Appearance:colorless transparent liquid Storage:Store in a cool, dry, well ventilated warehouse. Pac

Ethyl cyanoacetate

Cas:105-56-6

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

Ethyl cyanoacetate

Cas:105-56-6

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Cyanoacetic acid ethyl ester

Cas:105-56-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

105-56-6 Ethyl cyanoacetate

Cas:105-56-6

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

Ethyl cyanoacetate Basic information Product Name: Ethyl cyanoacetate Synonyms: 2-cyano-aceticacidethylester;Acetic acid,2-cyano-, ethyl ester;Aceticacid,cyano-,ethylester;Cyanacetate ethyle;cyanacetateethyle;Cyanessig

Ethyl cyanoacetate

Cas:105-56-6

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Business Custom Synthesis: Trading(Raw Mater

Ethyl cyanoacetate

Cas:105-56-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Ethyl cyanoacetate

Cas:105-56-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Ethyl cyanoacetate

Cas:105-56-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Ethyl cyanoacetate

Cas:105-56-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:Clear to very yellow liquid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:

ETHYL CYANOACETATE

Cas:105-56-6

Min.Order:200 Kilogram

Negotiable

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: Ethyl Cyanoacetate CAS No.:105-56-6 Molecule Formula:C5H7NO2 Molecule Weight:113.11 Purity: 99.0% Package: 200kg/drum Description:Colorless transparent liquid Manufacture Standards:Enterprise Standard

Best Quality Ethyl Cyanoacetate

Cas:105-56-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Ethyl Cyanoacetate

Cas:105-56-6

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

We are leading fine chemicals supplier in China with ISO certificate, Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...) 3.OLED

Ethyl cyanoacetateCAS NO.: 105-56-6

Cas:105-56-6

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

Hangzhou Fandachem Co.,Ltd, a China-based chemical company, specialize in exporting Ethyl cyanoacetate cas no: 105-56-6 Please contact us by email freely. We are leading exporter in China. If you really need this cargo, please do

Ethyl cyanoacetate cas no: 105-56-6

Cas:105-56-6

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service an

Ethyl cyanoacetate

Cas:105-56-6

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

Hangzhou Dingyan Chem is a leading manufacturer and supplier of chemicals in China.We develop,produce and distribute high quality pharmaceuticals, intermediates, special chemicals and other fine chemicals. We could give you: 1.Best qualit

Ethyl cyanoacetate

Cas:105-56-6

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Ethyl cyanoacetate

Cas:105-56-6

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

Ethyl cyanoacetate

Cas:105-56-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Fortuna Chemical Co.,Ltd

stable supply&competitive price Storage:Available Package:25KG Or as client requirement Application:Important pharm intermediate Transportation:By air or By sea

Ethyl cyanoacetate

Cas:105-56-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Ethyl cyanoacetate

Cas:105-56-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Ethyl cyanoacetate

Cas:105-56-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as

Ethyl cyanoacetate

Cas:105-56-6

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

Product Description Description & Specification Category Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug Standard Medical standard

factory supply CAS 105-56-6 with competitive price

Cas:105-56-6

Min.Order:1 Kilogram

FOB Price: $112.0

Type:Trading Company

inquiry

Synthetic route

3-(ethoxy)propionitrile
2141-62-0

3-(ethoxy)propionitrile

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
With N-hydroxyphthalimide; cobalt(II) acetate In acetonitrile at 190℃; under 6750.68 Torr; for 7h;
sodium 3-ethoxy-3-oxoprop-1-en-1-olate

sodium 3-ethoxy-3-oxoprop-1-en-1-olate

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
With hydroxylamine hydrochloride In ethanol at 90℃; for 4h; pH=2; pH-value; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;81%
ethanol
64-17-5

ethanol

cyanoacetic acid
372-09-8

cyanoacetic acid

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
With sulfuric acid In dichloromethane for 18h; Heating;95%
With sulfuric acid In dichloromethane for 18h; Reflux; Dean-Stark;95%
With sulfuric acid; sulfur trioxide at 20 - 70℃; for 4h; Temperature; Reflux;93.6%
hydrogen cyanide
74-90-8

hydrogen cyanide

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
With triethylamine at 15℃; for 4.83333h; Concentration; Reagent/catalyst; Solvent; Temperature; Time;94.2%
sodium cyanide
773837-37-9

sodium cyanide

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

A

diethyl 2-cyanosuccinate
10359-15-6

diethyl 2-cyanosuccinate

B

triethyl 2-cyano-1,2,3-propanetricarboxylate
20822-61-1

triethyl 2-cyano-1,2,3-propanetricarboxylate

C

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
With tetrabutylammomium bromide In dichloromethane; water at 20℃; for 4h;A 10.4%
B 5.4%
C 44%
ethanol
64-17-5

ethanol

cyanoacetic acid amide
107-91-5

cyanoacetic acid amide

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
With sulfuric acid for 3h; Time; Reflux;97%
With sulfuric acid for 3h; Reflux;97%
sodium cyanide
773837-37-9

sodium cyanide

hydrogen cyanide
74-90-8

hydrogen cyanide

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
With tetrabutylammomium bromide In water; acetonitrile at 55℃; for 2h; Product distribution / selectivity;93.2%
ethanol
64-17-5

ethanol

cyanoacetic acid
372-09-8

cyanoacetic acid

A

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

B

diethyl malonate
105-53-3

diethyl malonate

Conditions
ConditionsYield
With sulfuric acid In hexane; ethyl acetate at 30 - 62℃; for 5h; Temperature; Solvent; Dean-Stark;A 105.2 g
B 1.8 g
aspartic acid 4-ethyl ester
21860-86-6

aspartic acid 4-ethyl ester

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
With trichloroisocyanuric acid; sodium hydroxide In water at 20℃; for 6h; Temperature;85%
acetonitrile
75-05-8

acetonitrile

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
With sodium ethanolate; sodium amide; Diethyl carbonate at 140 - 160℃;
With sodium ethanolate; sodium amide; Diethyl carbonate at 140 - 160℃;
With sodium ethanolate; sodium amide; Diethyl carbonate at 140 - 160℃;
ethyl bromide
74-96-4

ethyl bromide

cyanoacetic acid
372-09-8

cyanoacetic acid

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
With sodium hydroxide; tetrabutylammomium bromide In water; chlorobenzene
ethyl iodide
75-03-6

ethyl iodide

cyanoacetic acid
372-09-8

cyanoacetic acid

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
With caesium carbonate In acetonitrile for 1.5h; Heating;98%
With cesium fluoride In N,N-dimethyl-formamide at 10 - 15℃; for 3h;79 % Chromat.
ethanol
64-17-5

ethanol

malononitrile
109-77-3

malononitrile

A

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

B

diethyl malonate
105-53-3

diethyl malonate

Conditions
ConditionsYield
With boron trifluoride diethyl etherate for 24h; Heating;A 90%
B 4%
With sulfuric acid at 130 - 135℃;
C11H16N4O2S
78514-93-9

C11H16N4O2S

A

1-isopropenyl-3-methylthio-1H-1,2,4-triazole
99496-77-2

1-isopropenyl-3-methylthio-1H-1,2,4-triazole

B

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
In acetic acid at 70℃; for 2h;A 66%
B n/a
ethyl pentacyanocyclopropanecarboxylate
205651-05-4

ethyl pentacyanocyclopropanecarboxylate

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
With N,N-Dimethylaniline hydroiodide In ethyl acetate at 50℃; for 0.0833333h; Decomposition;
potassium cyanide
151-50-8

potassium cyanide

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

A

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

B

methyl 2-cyanoacetate
105-34-0

methyl 2-cyanoacetate

Conditions
ConditionsYield
With methanol
acetonitrile
75-05-8

acetonitrile

Diethyl carbonate
105-58-8

Diethyl carbonate

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
With diethyl ether; sodium amide
benzaldehyde 2-cyano-2-ethoxycarbonylvinylamino(dimethylamino)methylenehydrazone
122604-89-1

benzaldehyde 2-cyano-2-ethoxycarbonylvinylamino(dimethylamino)methylenehydrazone

A

ethyl benzylidenecyanoacetate
2025-40-3

ethyl benzylidenecyanoacetate

B

α,α-bis(3-dimethylamino-1,2,4-triazol-1-yl)toluene
122604-96-0

α,α-bis(3-dimethylamino-1,2,4-triazol-1-yl)toluene

C

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
With acetic acid at 80℃; for 0.0833333h; Yield given;A n/a
B 30%
C n/a
With acetic acid at 80℃; for 0.0833333h; Yields of byproduct given;A n/a
B 30%
C n/a
N,N,N',N',N'',N''-Hexamethylguanidiniumcyanid
68897-45-0

N,N,N',N',N'',N''-Hexamethylguanidiniumcyanid

ethyl bromoacetate
105-36-2

ethyl bromoacetate

A

1,1,2,2,3,3-Hexamethylguanidiniumbromid
6926-43-8

1,1,2,2,3,3-Hexamethylguanidiniumbromid

B

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
In dichloromethane at 20℃; for 2h;A n/a
B 53%
ethanol
64-17-5

ethanol

malononitrile
109-77-3

malononitrile

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
With iron(III) chloride for 1h; Heating;76%
propynoic acid ethyl ester
623-47-2

propynoic acid ethyl ester

A

ethyl (Z)-3-azido-2-propenoate
116270-19-0

ethyl (Z)-3-azido-2-propenoate

B

E-ethyl 3-azidoacrylate
116270-20-3

E-ethyl 3-azidoacrylate

C

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

D

ethyl (Z)-3-(4-ethoxycarbonyl-1H-1,2,3-triazol-1-yl)propenoate
116270-21-4

ethyl (Z)-3-(4-ethoxycarbonyl-1H-1,2,3-triazol-1-yl)propenoate

Conditions
ConditionsYield
With borax; potassium dihydrogenphosphate; sodium azide In water at 50℃; for 0.5h; ultrasound irradiation; Yield given. Yields of byproduct given;
Cyanothioacetamide
7357-70-2

Cyanothioacetamide

3-bromo-1,1,1-trifluoroacetone
431-35-6

3-bromo-1,1,1-trifluoroacetone

ethanol
64-17-5

ethanol

A

2-[4-(trifluoromethyl)thiazol-2-yl]acetonitrile
329978-21-4

2-[4-(trifluoromethyl)thiazol-2-yl]acetonitrile

B

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
for 18h; Heating / reflux;
mer-hydrido[[(ethoxycarbonyl)methyl]cyano](ethyl cyanoacetate)tris(triphenylphosphine)ruthenium(II)
138614-14-9

mer-hydrido[[(ethoxycarbonyl)methyl]cyano](ethyl cyanoacetate)tris(triphenylphosphine)ruthenium(II)

1,2-bis-(diphenylphosphino)ethane
1663-45-2

1,2-bis-(diphenylphosphino)ethane

RuH((C6H5)2PCH2CH2P(C6H5)2)2(NCCHCOOC2H5)*0.5C6H6

RuH((C6H5)2PCH2CH2P(C6H5)2)2(NCCHCOOC2H5)*0.5C6H6

B

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
In benzene-d6 room temp., 3 h; NMR monitoring;A 82%
B 60%
2-chloropyrimidine
1722-12-9

2-chloropyrimidine

ethyl 5-oxo-2,5-dihydroisoxazole-4-carboxylate
54535-14-7

ethyl 5-oxo-2,5-dihydroisoxazole-4-carboxylate

A

ethyl 5-oxo-2-(pyrimidin-2-yl)-2,5-dihydroisoxazole-4-carboxylate
100422-78-4

ethyl 5-oxo-2-(pyrimidin-2-yl)-2,5-dihydroisoxazole-4-carboxylate

B

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
at 130℃; for 0.25h; Yields of byproduct given;A 62%
B n/a
Ethyl 2-acetyl-5-oxo-2,5-dihydroisoxazole-4-carboxylate
174902-47-7

Ethyl 2-acetyl-5-oxo-2,5-dihydroisoxazole-4-carboxylate

A

ethyl 2-methyloxazole-4-carboxylate
76284-27-0

ethyl 2-methyloxazole-4-carboxylate

B

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
at 540℃; under 0.05 Torr; for 1h;A 10%
B 90%
C15H13N3O2
1262279-87-7

C15H13N3O2

A

Benzylidenemalononitrile
2700-22-3

Benzylidenemalononitrile

B

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
With palladium 10% on activated carbon In methanol retro-Michael reaction;
potassium cyanide
151-50-8

potassium cyanide

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

3-(4-Bromo-benzoyl)-4-(4-bromo-phenyl)-1-cyano-4-hydroxy-2,6-diphenyl-cyclohexanecarboxylic acid ethyl ester
135885-92-6

3-(4-Bromo-benzoyl)-4-(4-bromo-phenyl)-1-cyano-4-hydroxy-2,6-diphenyl-cyclohexanecarboxylic acid ethyl ester

A

(E)-1-(4-bromophenyl)-3-phenylprop-2-en-1-one
72758-69-1, 2403-27-2, 22966-23-0

(E)-1-(4-bromophenyl)-3-phenylprop-2-en-1-one

B

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
With sodium ethanolate In ethanol Heating;A 86%
B n/a
With sodium ethanolate In ethanol at 50℃; Kinetics; Further Variations:; Temperatures;
3-Benzoyl-2,6-bis-(4-chloro-phenyl)-1-cyano-4-hydroxy-4-phenyl-cyclohexanecarboxylic acid ethyl ester
83624-73-1

3-Benzoyl-2,6-bis-(4-chloro-phenyl)-1-cyano-4-hydroxy-4-phenyl-cyclohexanecarboxylic acid ethyl ester

B

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
With sodium ethanolate In ethanol Heating;A 87%
B n/a
With sodium ethanolate In ethanol at 50℃; Kinetics; Further Variations:; Temperatures;
3-Benzoyl-2,6-bis-(4-bromo-phenyl)-1-cyano-4-hydroxy-4-phenyl-cyclohexanecarboxylic acid ethyl ester
135885-91-5

3-Benzoyl-2,6-bis-(4-bromo-phenyl)-1-cyano-4-hydroxy-4-phenyl-cyclohexanecarboxylic acid ethyl ester

A

(2E)-3-(4-bromophenyl)-1-phenylprop-2-en-1-one
22966-09-2

(2E)-3-(4-bromophenyl)-1-phenylprop-2-en-1-one

B

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Conditions
ConditionsYield
With sodium ethanolate In ethanol Heating;A 85%
B n/a
With sodium ethanolate In ethanol at 50℃; Kinetics; Further Variations:; Temperatures;
morpholine
110-91-8

morpholine

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

4-cyanoacetylmorpholine
15029-32-0

4-cyanoacetylmorpholine

Conditions
ConditionsYield
In neat (no solvent) at 20℃; Inert atmosphere;100%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In 2-methyltetrahydrofuran at 40℃; for 4h;87%
at 130℃; for 4h;75%
furfural
98-01-1

furfural

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

ethyl (E)-2-cyano-3-(2-furyl)-2-propenoate
67449-75-6, 23973-22-0

ethyl (E)-2-cyano-3-(2-furyl)-2-propenoate

Conditions
ConditionsYield
With L-proline for 0.0333333h; Knoevenagel condensation; microwave irradiation;100%
ytterbium(III) perfluorooctanesulfonate In toluene at 80℃; for 3h; Knoevenagel condensation;99%
With polyacrylonitrile fiber modified with triethylenetetramine In water at 50℃; for 1.5h; Knoevenagel condensation;99%
1-phenylmethyl-4-piperidone
3612-20-2

1-phenylmethyl-4-piperidone

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

ethyl 2-(1-benzylpiperidin-4-ylidene)-2-cyanoacetate
1463-52-1

ethyl 2-(1-benzylpiperidin-4-ylidene)-2-cyanoacetate

Conditions
ConditionsYield
With acetic acid In toluene at 20℃; for 4h; Heating / reflux;100%
With ammonium acetate; acetic acid; benzene Abtrennen des entstehenden H2O;
With triethylamine In dichloromethane at 20℃;
cyclohexanone
108-94-1

cyclohexanone

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

ethyl 2-cyano-2-cyclohexylideneacetate
6802-76-2

ethyl 2-cyano-2-cyclohexylideneacetate

Conditions
ConditionsYield
With 1,4-diaza-bicyclo[2.2.2]octane In neat liquid at 20℃; for 0.133333h; Knoevenagel Condensation; Green chemistry;100%
With third generation polystyrene supported poly(amidoamine) dendrimer In ethanol at 50℃; for 0.333333h; Knoevenagel condensation;98%
With ammonium acetate; acetic acid In toluene Knoevenagel Condensation; Reflux;97%
2-chloro-benzaldehyde
89-98-5

2-chloro-benzaldehyde

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

(E)-ethyl 3-(2-chlorophenyl)-2-cyanoacrylate
24393-43-9

(E)-ethyl 3-(2-chlorophenyl)-2-cyanoacrylate

Conditions
ConditionsYield
With IRA-96 anion-exchange resin In ethanol at 25 - 30℃; for 1h; Reagent/catalyst; Knoevenagel Condensation; Sonication; Green chemistry; stereoselective reaction;100%
With polyacrylonitrile fiber functionalized with N,N-dimethyl-1,3-propanediamine In ethanol for 1.5h; Knoevenagel condensation; Reflux;99%
With polystyrene-supported DABCO In methanol at 45℃; for 1.5h; Knoevenagel Condensation; Green chemistry; stereoselective reaction;99%
3-nitro-benzaldehyde
99-61-6

3-nitro-benzaldehyde

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

(E)-2-cyano-3-(3-nitrophenyl)-2-propenoic acid ethyl ester
18925-00-3, 14394-75-3

(E)-2-cyano-3-(3-nitrophenyl)-2-propenoic acid ethyl ester

Conditions
ConditionsYield
With L-proline for 0.1h; Knoevenagel condensation; microwave irradiation;100%
With third generation polystyrene supported poly(amidoamine) dendrimer In ethanol at 50℃; for 0.333333h; Knoevenagel condensation;100%
With polyacrylonitrile fiber functionalized with N,N-dimethyl-1,3-propanediamine In ethanol for 1.5h; Knoevenagel condensation; Reflux;99%
benzaldehyde
100-52-7

benzaldehyde

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

ethyl (E)-2-cyano-3-phenyl-2-propenoate
2169-69-9

ethyl (E)-2-cyano-3-phenyl-2-propenoate

Conditions
ConditionsYield
With tetramethyl ammoniumhydroxide at 60℃; for 0.5h; Condensation; Knoevenagel condensation;100%
With L-proline for 0.0833333h; Knoevenagel condensation; microwave irradiation;100%
ytterbium(III) perfluorooctanesulfonate In toluene at 80℃; for 8h; Knoevenagel condensation;100%
benzaldehyde
100-52-7

benzaldehyde

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

ethyl benzylidenecyanoacetate
2025-40-3

ethyl benzylidenecyanoacetate

Conditions
ConditionsYield
With polymer supported poly(propylene imine)dendrimer In ethanol at 20℃; for 0.0833333h; Knoevenagel Condensation; Green chemistry;100%
With N,N-dimethyl-cyclohexanamine In water at 20℃; Knoevenagel Condensation;100%
With mesoporous hybrid catalyst HYB-75P-25B In ethanol at 59.84℃; for 3.5h; Knoevenagel condensation; Inert atmosphere;99%
4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

ethyl (E)-2-cyano-3-(4-hydroxyphenyl)-2-propenoate
6935-44-0, 42205-38-9

ethyl (E)-2-cyano-3-(4-hydroxyphenyl)-2-propenoate

Conditions
ConditionsYield
With third generation polystyrene supported poly(amidoamine) dendrimer In ethanol at 50℃; for 0.25h; Knoevenagel condensation;100%
Ru(+)Cp(NCCHCO2Et)(-)*(PPh3)2 In tetrahydrofuran at 25℃; for 5h; Condensation; Aldol reaction;99%
With polyacrylonitrile fiber functionalized with N,N-dimethyl-1,3-propanediamine In ethanol for 1.5h; Knoevenagel condensation; Reflux;99%
4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

ethyl (2E)-2-cyano-3-(4-methoxyphenyl)acrylate
2017-87-0

ethyl (2E)-2-cyano-3-(4-methoxyphenyl)acrylate

Conditions
ConditionsYield
With diazabicyclo[5.4.0]undec-7-ene-water complex at 20℃; for 0.833333h; Knoevenagel condensation;100%
With ethylenediamine-modified poly(vinyl chloride) at 20℃; for 0.0666667h; Solvent; Knoevenagel Condensation; Green chemistry;100%
With third generation polystyrene supported poly(amidoamine) dendrimer In ethanol at 50℃; for 0.25h; Knoevenagel condensation;99%
4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

ethyl 2-cyano-3-(4-methoxyphenyl)prop-2-enoate
2286-29-5

ethyl 2-cyano-3-(4-methoxyphenyl)prop-2-enoate

Conditions
ConditionsYield
With polymer supported poly(propylene imine)dendrimer In ethanol at 20℃; for 0.0833333h; Knoevenagel Condensation; Green chemistry;100%
In N,N-dimethyl-formamide for 0.166667h; Knoevenagel Condensation;99.4%
With N-aminoethylpiperazine functionalized C60 fullerene In ethanol at 60℃; for 1h; Knoevenagel Condensation;99%
vanillin
121-33-5

vanillin

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

2-cyano-3-(4-hydroxy-3-methoxyphenyl)acrylic acid ethyl ester
132464-93-8, 13373-29-0

2-cyano-3-(4-hydroxy-3-methoxyphenyl)acrylic acid ethyl ester

Conditions
ConditionsYield
With polymer supported poly(propylene imine)dendrimer In ethanol at 20℃; for 0.166667h; Knoevenagel Condensation; Green chemistry;100%
With ammonium sulphamate for 0.00416667h; Knoevenagel condensation; Microwave irradiation; neat (no solvent);96%
aluminum oxide In ethanol for 1.66667h; Heating;95%
3,4-dimethoxy-benzaldehyde
120-14-9

3,4-dimethoxy-benzaldehyde

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

ethyl α-cyano-β-(3,4-dimethoxyphenyl)acrylate
2286-55-7

ethyl α-cyano-β-(3,4-dimethoxyphenyl)acrylate

Conditions
ConditionsYield
With piperidine; acetic acid In benzene at 120 - 130℃; for 12h; Heating / reflux;100%
With polymer supported poly(propylene imine)dendrimer In ethanol at 20℃; for 0.166667h; Knoevenagel Condensation; Green chemistry;99%
With ammonium sulphamate for 0.00416667h; Knoevenagel condensation; Microwave irradiation; neat (no solvent);97%
methyl vinyl ketone
78-94-4

methyl vinyl ketone

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

2-cyano-5-oxo-2-(3-oxobutyl)hexanoic acid ethyl ester

2-cyano-5-oxo-2-(3-oxobutyl)hexanoic acid ethyl ester

Conditions
ConditionsYield
With triphenylphosphine In acetonitrile at 23℃; for 0.133333h;100%
With N-ethyl-N,N-diisopropylamine; 2,6-(NMe2)2PhPd(1+)*BF4(1-) In dichloromethane at 20℃; Product distribution; Kinetics; Further Variations:; Catalysts; double Michael reaction;100%
With [2,6-bis(4',4'-dimethyl-2'-oxazolinyl)phenyl](acetonitrile)nickel(II) tetrafluoroborate; N-ethyl-N,N-diisopropylamine In dichloromethane at 0℃; for 1h; Michael addition;100%
cyclopentanone
120-92-3

cyclopentanone

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

ethyl 2-cyano-2-cyclopentylideneacetate
5407-83-0

ethyl 2-cyano-2-cyclopentylideneacetate

Conditions
ConditionsYield
piperidine at 23℃; under 750.06 Torr; for 2h; Knoevenagel condensation;100%
With morpholine; bis(acetylacetonate)oxovanadium at 40℃; for 1h; Reagent/catalyst; Temperature; Time; Knoevenagel Condensation;99%
With ammonium acetate; acetic acid In toluene Knoevenagel Condensation; Reflux;93%
ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

ortho-anisaldehyde
135-02-4

ortho-anisaldehyde

(E)-2-cyano-3-(2-methoxyphenyl)-2-propenoic acid ethyl ester
14533-89-2

(E)-2-cyano-3-(2-methoxyphenyl)-2-propenoic acid ethyl ester

Conditions
ConditionsYield
With L-proline for 0.0666667h; Knoevenagel condensation; microwave irradiation;100%
With polyacrylonitrile fiber modified with triethylenetetramine In water at 50℃; for 1.5h; Knoevenagel condensation;99%
calcined Mg-Al-layered double hydroxide-supported iPr2-amide In N,N-dimethyl-formamide at 20℃; for 0.25h; Knoevenagel condensation;98%
ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

4-dimethylamino-benzaldehyde
100-10-7

4-dimethylamino-benzaldehyde

ethyl (E)-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enoate
1886-52-8, 74897-86-2, 14394-77-5

ethyl (E)-2-cyano-3-[4-(dimethylamino)phenyl]prop-2-enoate

Conditions
ConditionsYield
With third generation polystyrene supported poly(amidoamine) dendrimer In ethanol at 50℃; for 0.25h; Knoevenagel condensation;100%
With diazabicyclo[5.4.0]undec-7-ene-water complex at 20℃; for 1h; Knoevenagel condensation;100%
With polyacrylonitrile fiber functionalized with N,N-dimethyl-1,3-propanediamine In ethanol for 1.5h; Knoevenagel condensation; Reflux;99%
ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

cyanoacetic acid amide
107-91-5

cyanoacetic acid amide

Conditions
ConditionsYield
With ammonia100%
With ammonia In tetrahydrofuran; water at 20℃; for 2h;93%
With ammonium hydroxide In tetrahydrofuran at 20℃; for 24h;91%
4-methyl-benzaldehyde
104-87-0

4-methyl-benzaldehyde

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

ethyl (E)-2-cyano-3-p-tolylacrylate
2017-88-1

ethyl (E)-2-cyano-3-p-tolylacrylate

Conditions
ConditionsYield
With L-proline for 0.0833333h; Knoevenagel condensation; microwave irradiation;100%
With 1,4-diaza-bicyclo[2.2.2]octane In neat liquid at 20℃; for 0.0166667h; Knoevenagel Condensation; Green chemistry;100%
With ASCPEI In ethanol at 43℃; for 3h; Knoevenagel condensation;99%
vanillin
121-33-5

vanillin

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

ethyl (E)-2-cyano-3-(3-methoxy 4-hydroxyphenyl)-2-propenoate
132464-93-8

ethyl (E)-2-cyano-3-(3-methoxy 4-hydroxyphenyl)-2-propenoate

Conditions
ConditionsYield
With third generation polystyrene supported poly(amidoamine) dendrimer In ethanol at 50℃; for 0.333333h; Knoevenagel condensation;100%
With aluminum oxide; potassium oxide at 23℃; for 3h; Knoevenagel condensation;97%
With dimethyl 3-methyl-9-oxo-7-(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)-2,4-di(pyridin-2-yl)-3,7-diazabicyclo-[3.3.1]nonane-1,5-dicarboxylate In water at 40℃; for 2h; Knoevenagel Condensation;96%
3,4-dimethoxy-benzaldehyde
120-14-9

3,4-dimethoxy-benzaldehyde

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

ethyl (E)-2-cyano-3-(3,4-dimethoxyphenyl)-2-propenoate
24393-47-3

ethyl (E)-2-cyano-3-(3,4-dimethoxyphenyl)-2-propenoate

Conditions
ConditionsYield
With third generation polystyrene supported poly(amidoamine) dendrimer In ethanol at 50℃; for 0.333333h; Knoevenagel condensation;100%
With ASCPEI In ethanol at 43℃; for 2h; Knoevenagel condensation;98%
With ammonium acetate for 0.25h; Knoevenagel condensation; microwave irradiation;94%
isopropylamine
75-31-0

isopropylamine

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

2-cyano-N-isopropylacetamide
52573-74-7

2-cyano-N-isopropylacetamide

Conditions
ConditionsYield
for 18h;100%
With sodium hydroxide
(E)-3-phenylpropenal
14371-10-9

(E)-3-phenylpropenal

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

(2E,4E)-2-cyano-5-phenyl-2,4-pentadienoic acid ethyl ester
41109-95-9

(2E,4E)-2-cyano-5-phenyl-2,4-pentadienoic acid ethyl ester

Conditions
ConditionsYield
With 1,4-diaza-bicyclo[2.2.2]octane In neat liquid at 20℃; for 0.25h; Knoevenagel Condensation; Green chemistry;100%
With zinc(II) chloride at 100℃; for 1.5h;92%
With 1-methyl-piperazine at 25 - 30℃; for 0.166667h; Knoevenagel condensation;91%
ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

Cyclopropylamine
765-30-0

Cyclopropylamine

2-cyano-N-cyclopropylacetamide
15029-37-5

2-cyano-N-cyclopropylacetamide

Conditions
ConditionsYield
at 45℃; for 1.5h;100%
at 38℃; for 2.33333h;91%
In ethanol at 20℃;82%
4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

ethyl (E)-2-cyano-3-(4-fluorophenyl)-2-propenoate
18861-57-9, 50737-52-5

ethyl (E)-2-cyano-3-(4-fluorophenyl)-2-propenoate

Conditions
ConditionsYield
With 1-(3-silica-supported propyl)-3-[(3-{[1-(3-silica-supported propyl)-4,5-dihydro-1H-imidazol-3-ium-3-yl]methyl}-2,4,6-trimethylphenyl)methyl]-4,5-dihydro-1H-imidazol-3-ium chloride at 130℃; for 2h; Knoevenagel condensation;100%
With polyacrylonitrile fiber functionalized with N,N-dimethyl-1,3-propanediamine In ethanol for 1.5h; Knoevenagel condensation; Reflux;99%
With N-(propylcarbamoyl)sulfamic acid bonded on silica at 100℃; for 0.25h;97%
4-chlorobenzaldehyde
104-88-1

4-chlorobenzaldehyde

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

ethyl (E)-3-(4-chlorophenyl)-2-cyanoacrylate
2169-68-8

ethyl (E)-3-(4-chlorophenyl)-2-cyanoacrylate

Conditions
ConditionsYield
With L-proline for 0.0333333h; Knoevenagel condensation; microwave irradiation;100%
With IRA-96 anion-exchange resin In ethanol at 25 - 30℃; for 1h; Reagent/catalyst; Knoevenagel Condensation; Sonication; Green chemistry; stereoselective reaction;100%
With ammonium acetate; acetic acid for 0.0111111h; Knoevenagel condensation; Irradiation;99%
2-aminoacetophenone
551-93-9

2-aminoacetophenone

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

1,2-dihydro-2-oxo-4-methylquinoline-3-carbonitrile
28448-12-6

1,2-dihydro-2-oxo-4-methylquinoline-3-carbonitrile

Conditions
ConditionsYield
With ammonium acetate for 1h; Heating;100%
cerium(III) chloride for 0.1h; microwave irradiation;86%
With ammonium acetate at 220℃; for 0.25h;78%
4-nitrobenzaldehdye
555-16-8

4-nitrobenzaldehdye

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

(E)-ethyl 2-cyano-3-(4-nitrophenyl)acrylate
2017-89-2

(E)-ethyl 2-cyano-3-(4-nitrophenyl)acrylate

Conditions
ConditionsYield
With L-proline for 0.1h; Knoevenagel condensation; microwave irradiation;100%
With third generation polystyrene supported poly(amidoamine) dendrimer In ethanol at 50℃; for 0.333333h; Knoevenagel condensation;100%
With 1,4-diaza-bicyclo[2.2.2]octane In neat liquid at 20℃; for 0.0333333h; Knoevenagel Condensation; Green chemistry;100%
4-nitrobenzaldehdye
555-16-8

4-nitrobenzaldehdye

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

ethyl (Z)-2-cyano-3-(4-nitrophenyl)propenoate
96238-12-9

ethyl (Z)-2-cyano-3-(4-nitrophenyl)propenoate

Conditions
ConditionsYield
hydrotalcite structure integrating fluoride ions In acetonitrile at 60℃; for 1.5h; Conversion of starting material; Knoevenagel Condensation;100%
With PEG-600 at 20℃; for 0.25h; Knoevenagel condensation;95%
With lipase lipoprotein from Aspergillus niger In dimethyl sulfoxide at 35℃; for 48h; Knoevenagel Condensation; Green chemistry; Enzymatic reaction;94%
3,4,5-trimethoxy-benzaldehyde
86-81-7

3,4,5-trimethoxy-benzaldehyde

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

2-cyano-3-(3,4,5-trimethoxyphenyl)acrylic acid ethyl ester
2601-03-8

2-cyano-3-(3,4,5-trimethoxyphenyl)acrylic acid ethyl ester

Conditions
ConditionsYield
With ytterbium(III) triflate at 80 - 85℃; Knoevenagel condensation; neat (no solvent);100%
With recovered palladium catalyst In ethanol at 20℃; for 18h; Knoevenagel Condensation; Green chemistry;97%
With montmorillonitesilylpropylidenediamine In toluene Ambient temperature;96%
With piperidine In ethanol at 20℃;
In ethanol at 20℃; Knoevenagel Condensation; Sonication;
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