Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:196597-78-1
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryHangzhou Dingyan Chem is a leading manufacturer and supplier of chemicals in China.We develop,produce and distribute high quality pharmaceuticals, intermediates, special chemicals and other fine chemicals. We could give you: 1.Best qua
Cas:196597-78-1
Min.Order:1 Kilogram
FOB Price: $1800.0 / 2400.0
Type:Manufacturers
inquiryProduct Description Product website: http://www.finerchem.com/pro01en/id/1200.html Product Name 1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one CAS No.
Cas:196597-78-1
Min.Order:1 Gram
FOB Price: $45.0
Type:Lab/Research institutions
inquiry1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one CAS No.:196597-78-1 Name: 1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one Molecular Structure: Molecular Formula: C11H10O2 Molecular Weight: 174.2 CAS Reg
Cas:196597-78-1
Min.Order:1 Kilogram
FOB Price: $2.0
Type:Other
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Cas:196597-78-1
Min.Order:1
Negotiable
Type:Other
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:196597-78-1
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryProduct Name: 1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one Synonyms: 1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one;1,2,6,7-Tetrahydro-8H-indeno[5,4-β]furan-8-one;1,2,6,7-tetrahydroindeno[5,4-b]furan-8-one;Ramelteon Inte
Cas:196597-78-1
Min.Order:1 Kilogram
FOB Price: $8900.0
Type:Lab/Research institutions
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:196597-78-1
Min.Order:10 Gram
FOB Price: $146.0 / 176.0
Type:Trading Company
inquiry1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W
Cas:196597-78-1
Min.Order:1 Kilogram
FOB Price: $289.0 / 499.0
Type:Trading Company
inquiryName: 1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one Synonyms: 1,2,6,7-Tetrahydro-8H-indeno[5,4-β]furan-8-one CAS:196597-78-1 MF: C11H10O2 Appearance: white powder Storage:Store in cool and dry place, away from sun light. Package: 25kgs
Cas:196597-78-1
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Other
inquiryOur Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con
Cas:196597-78-1
Min.Order:1 Kilogram
FOB Price: $1.0 / 10.0
Type:Trading Company
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:196597-78-1
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese
Cas:196597-78-1
Min.Order:1 Gram
FOB Price: $16.0 / 19.0
Type:Trading Company
inquiry1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one CAS:196597-78-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing i
Cas:196597-78-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:196597-78-1
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHebei Mojin Biotechnology Co., Ltd, Our company is a professional chemical raw materials and chemical reagents research and development production enterprises. We have several production line,So we can control the lowest price. We also have several
Cas:196597-78-1
Min.Order:25 Gram
FOB Price: $90.0 / 100.0
Type:Trading Company
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:196597-78-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryBest quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
Cas:196597-78-1
Min.Order:0
Negotiable
Type:Manufacturers
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:196597-78-1
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
Cas:196597-78-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryA substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:196597-78-1
Min.Order:4 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry1. Product advantages: exquisite appearance and unique functions. 2. Product Advantages: Our products are the best,fast speed ,in large stock 3. High-quality products and thoughtful service are your greatest satisfaction. 4. The product
Cas:196597-78-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryadvantage: 1. The best price, satisfactory quality; 2. customers have the right to choose the delivery of parcels (EMS, DHL, FedEx, UPS); 3. customers have the right to choose from the recent effective packaging methods of their products packaging
Cas:196597-78-1
Min.Order:1 Gram
Negotiable
Type:Other
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:196597-78-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:196597-78-1
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Cas:196597-78-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryGMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
Cas:196597-78-1
Min.Order:1 Milligram
Negotiable
Type:Trading Company
inquiryProduct Name: 1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one Synonyms: 1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-one;1,2,6,7-Tetrahydro-8H-indeno[5,4-β]furan-8-one;RaMelteon I;4-b]furan-8-one;7-tetrahydro-;8H-Indeno[5;1,2,6,7-tetrahydroin
Cas:196597-78-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:196597-78-1
Min.Order:1 Kilogram
FOB Price: $18.0 / 20.0
Type:Trading Company
inquiryMy Company Changchun Artel Import and Export trade companyImport and Export Trade Co., Ltd.is located in Changchun, a national historical and cultural city, Jilin Province, China. It covers an area of 22,000 square meters, construction area
Cas:196597-78-1
Min.Order:20 Metric Ton
Negotiable
Type:Trading Company
inquiry1-(2,3-dihydrobenzofuran-4-yl)-2-propen-1-one
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With copper(II) bis(trifluoromethanesulfonate) In 1,2-dichloro-ethane at 10 - 20℃; for 16h; Solvent; Reagent/catalyst; | 96.3% |
With sulfuric acid In pentane at 67℃; Product distribution / selectivity; Inert atmosphere; | |
With sulfuric acid In water; pentane at 67℃; for 0.5h; Inert atmosphere; |
4,5-dibromo-1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-one
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With hydrogen; acetic acid; 10percent Pd/C/H2O at 20℃; for 1h; | 89% |
With hydrogen; sodium acetate; 5% palladium over charcoal In water; acetic acid at 20℃; | 89% |
With hydrogen; sodium acetate; palladium 10% on activated carbon In methanol at 40℃; under 2175.22 - 3675.37 Torr; for 8h; | 88.6% |
4,5-dibromo-1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-one
A
C11H12O
B
2,6,7,8-tetrahydro-1H-indeno[5,4-b]furan-8-ol
C
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With hydrogen; sodium acetate; acetic acid; palladium 10% on activated carbon under 1471.14 - 2206.72 Torr; | A n/a B n/a C 85% |
6,7-dihydro-8H-indeno-[5,4-b]furan-8-one
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With hydrogen; 5% Pd(II)/C(eggshell); triethylamine In tetrahydrofuran; ethanol at 35℃; under 4500.45 - 5250.53 Torr; for 24h; | 62% |
4-tert-butyl-1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-one
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With hydrogenchloride; aluminum (III) chloride In benzene | 20% |
2,3-Dihydrobenzofuran
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
Multi-step reaction with 9 steps 1.1: 92 percent / TiCl4 / CH2Cl2 / 1 h 2.1: NaH / tetrahydrofuran / 0.33 h / 20 °C 2.2: 88 percent / tetrahydrofuran / 1 h / 20 °C 3.1: 99 percent / H2 / 10percent Pd/C/H2O / ethanol / 2 h / 20 °C 4.1: 97 percent / NaOAc; AcOH; Br2 / 1 h / 20 °C 5.1: 53 percent / AcOH; Fe; Br2 / 5 h / 50 °C 6.1: 93 percent / aq. KOH / ethanol / 1 h / 90 °C 7.1: SOCl2 / 75 °C 8.1: AlCl3 / 1,2-dichloro-ethane / 20 °C 9.1: 89 percent / AcOH; H2 / 10percent Pd/C/H2O / 1 h / 20 °C View Scheme | |
Multi-step reaction with 9 steps 1.1: 86 percent / POCl3 / 12 h / 80 - 85 °C 2.1: NaH / tetrahydrofuran / 0.33 h / 20 °C 2.2: 88 percent / tetrahydrofuran / 1 h / 20 °C 3.1: 99 percent / H2 / 10percent Pd/C/H2O / ethanol / 2 h / 20 °C 4.1: 97 percent / NaOAc; AcOH; Br2 / 1 h / 20 °C 5.1: 53 percent / AcOH; Fe; Br2 / 5 h / 50 °C 6.1: 93 percent / aq. KOH / ethanol / 1 h / 90 °C 7.1: SOCl2 / 75 °C 8.1: AlCl3 / 1,2-dichloro-ethane / 20 °C 9.1: 89 percent / AcOH; H2 / 10percent Pd/C/H2O / 1 h / 20 °C View Scheme | |
Multi-step reaction with 6 steps 1.1: trichlorophosphate / 5.17 h / 30 - 98 °C 2.1: sodium methylate / toluene / 0.25 h / 0 - 30 °C 3.1: hydrogen / nickel / methanol / 4 h / 50 °C 4.1: bromine; sodium acetate; acetic acid / 14 h / 20 - 28 °C 5.1: thionyl chloride / N,N-dimethyl-formamide / 1,2-dichloro-benzene / 2 h / 28 - 60 °C 5.2: 1 h / -5 - 5 °C 6.1: hydrogen; sodium acetate / raney chloride / methanol / 50 °C View Scheme |
2,3-dihydro-benzofuran-5-carbaldehyde
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
Multi-step reaction with 8 steps 1.1: NaH / tetrahydrofuran / 0.33 h / 20 °C 1.2: 88 percent / tetrahydrofuran / 1 h / 20 °C 2.1: 99 percent / H2 / 10percent Pd/C/H2O / ethanol / 2 h / 20 °C 3.1: 97 percent / NaOAc; AcOH; Br2 / 1 h / 20 °C 4.1: 53 percent / AcOH; Fe; Br2 / 5 h / 50 °C 5.1: 93 percent / aq. KOH / ethanol / 1 h / 90 °C 6.1: SOCl2 / 75 °C 7.1: AlCl3 / 1,2-dichloro-ethane / 20 °C 8.1: 89 percent / AcOH; H2 / 10percent Pd/C/H2O / 1 h / 20 °C View Scheme | |
Multi-step reaction with 5 steps 1.1: sodium methylate / toluene / 0.25 h / 0 - 30 °C 2.1: hydrogen / nickel / methanol / 4 h / 50 °C 3.1: bromine; sodium acetate; acetic acid / 14 h / 20 - 28 °C 4.1: thionyl chloride / N,N-dimethyl-formamide / 1,2-dichloro-benzene / 2 h / 28 - 60 °C 4.2: 1 h / -5 - 5 °C 5.1: hydrogen; sodium acetate / raney chloride / methanol / 50 °C View Scheme | |
Multi-step reaction with 6 steps 1.1: piperidine; pyridine / 6 h / 120 °C 2.1: thionyl chloride / 0.67 h / 26 - 73 °C / Heating / reflux 3.1: hydrogen / nickel / methanol / 4 h / 50 °C 4.1: bromine; sodium acetate; acetic acid / 14 h / 20 - 28 °C 5.1: thionyl chloride / N,N-dimethyl-formamide / 1,2-dichloro-benzene / 2 h / 28 - 60 °C 5.2: 1 h / -5 - 5 °C 6.1: hydrogen; sodium acetate / raney chloride / methanol / 50 °C View Scheme | |
Multi-step reaction with 5 steps 1.1: piperidine; pyridine; acetic acid / 4 - 5 h / 100 °C 1.2: 2 - 3 h / 20 °C 2.1: sodium hydroxide; hydrogen; ammonium formate / palladium 10% on activated carbon / water / 5 - 6 h / 20 °C 3.1: bromine; sodium acetate; acetic acid / 2 - 3 h / 0 - 45 °C 4.1: thionyl chloride / N,N-dimethyl-formamide / 1 - 2 h / 20 °C 4.2: 1 - 2 h / 0 - 5 °C 5.1: hydrogen; sodium acetate; acetic acid / palladium 10% on activated carbon / 1471.14 - 2206.72 Torr View Scheme | |
Multi-step reaction with 6 steps 1: sodium t-butanolate / toluene / 1 h 2: acetic acid; hydrogen; 5%-palladium/activated carbon / 1 h / 50 °C / 1470.15 - 2205.22 Torr 3: acetic acid; sodium acetate; bromine / 6 h / 20 °C / Cooling 4: thionyl chloride / 1,2-dichloro-benzene; N,N-dimethyl-formamide / 42 °C 5: aluminum (III) chloride / 0.5 h / Cooling with ice 6: hydrogen; sodium acetate; palladium 10% on activated carbon / methanol / 2 h / 40 °C / 2205.22 - 3675.37 Torr View Scheme |
ethyl (E)-3-(2,3-dihydrobenzofuran-5-yl)-2-propenoate
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
Multi-step reaction with 7 steps 1: 99 percent / H2 / 10percent Pd/C/H2O / ethanol / 2 h / 20 °C 2: 97 percent / NaOAc; AcOH; Br2 / 1 h / 20 °C 3: 53 percent / AcOH; Fe; Br2 / 5 h / 50 °C 4: 93 percent / aq. KOH / ethanol / 1 h / 90 °C 5: SOCl2 / 75 °C 6: AlCl3 / 1,2-dichloro-ethane / 20 °C 7: 89 percent / AcOH; H2 / 10percent Pd/C/H2O / 1 h / 20 °C View Scheme | |
Multi-step reaction with 5 steps 1: acetic acid; hydrogen; 5%-palladium/activated carbon / 1 h / 50 °C / 1470.15 - 2205.22 Torr 2: acetic acid; sodium acetate; bromine / 6 h / 20 °C / Cooling 3: thionyl chloride / 1,2-dichloro-benzene; N,N-dimethyl-formamide / 42 °C 4: aluminum (III) chloride / 0.5 h / Cooling with ice 5: hydrogen; sodium acetate; palladium 10% on activated carbon / methanol / 2 h / 40 °C / 2205.22 - 3675.37 Torr View Scheme |
ethyl 3-(2,3-dihydro-1-benzofuran-5-yl)propanoate
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: 97 percent / NaOAc; AcOH; Br2 / 1 h / 20 °C 2: 53 percent / AcOH; Fe; Br2 / 5 h / 50 °C 3: 93 percent / aq. KOH / ethanol / 1 h / 90 °C 4: SOCl2 / 75 °C 5: AlCl3 / 1,2-dichloro-ethane / 20 °C 6: 89 percent / AcOH; H2 / 10percent Pd/C/H2O / 1 h / 20 °C View Scheme | |
Multi-step reaction with 3 steps 1.1: bromine; sodium acetate; acetic acid / 14 h / 20 - 28 °C 2.1: thionyl chloride / N,N-dimethyl-formamide / 1,2-dichloro-benzene / 2 h / 28 - 60 °C 2.2: 1 h / -5 - 5 °C 3.1: hydrogen; sodium acetate / raney chloride / methanol / 50 °C View Scheme | |
Multi-step reaction with 4 steps 1: acetic acid; sodium acetate; bromine / 6 h / 20 °C / Cooling 2: thionyl chloride / 1,2-dichloro-benzene; N,N-dimethyl-formamide / 42 °C 3: aluminum (III) chloride / 0.5 h / Cooling with ice 4: hydrogen; sodium acetate; palladium 10% on activated carbon / methanol / 2 h / 40 °C / 2205.22 - 3675.37 Torr View Scheme |
ethyl 3-(7-bromo-2,3-dihydro-1-benzofuran-5-yl)propanoate
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 53 percent / AcOH; Fe; Br2 / 5 h / 50 °C 2: 93 percent / aq. KOH / ethanol / 1 h / 90 °C 3: SOCl2 / 75 °C 4: AlCl3 / 1,2-dichloro-ethane / 20 °C 5: 89 percent / AcOH; H2 / 10percent Pd/C/H2O / 1 h / 20 °C View Scheme |
3-(6,7-dibromo-2,3-dihydro-benzofuran-5-yl)-propionyl chloride
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: AlCl3 / 1,2-dichloro-ethane / 20 °C 2: 89 percent / AcOH; H2 / 10percent Pd/C/H2O / 1 h / 20 °C View Scheme | |
Multi-step reaction with 2 steps 1: aluminum (III) chloride / 0.5 h / Cooling with ice 2: hydrogen; sodium acetate; palladium 10% on activated carbon / methanol / 2 h / 40 °C / 2205.22 - 3675.37 Torr View Scheme |
ethyl 3-(6,7-dibromo-2,3-dihydrobenzofuran-5-yl) propionic acid
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: SOCl2 / 75 °C 2: AlCl3 / 1,2-dichloro-ethane / 20 °C 3: 89 percent / AcOH; H2 / 10percent Pd/C/H2O / 1 h / 20 °C View Scheme | |
Multi-step reaction with 2 steps 1.1: thionyl chloride / N,N-dimethyl-formamide / 1,2-dichloro-benzene / 2 h / 28 - 60 °C 1.2: 1 h / -5 - 5 °C 2.1: hydrogen; sodium acetate / raney chloride / methanol / 50 °C View Scheme | |
Multi-step reaction with 2 steps 1.1: thionyl chloride / N,N-dimethyl-formamide / 1 - 2 h / 20 °C 1.2: 1 - 2 h / 0 - 5 °C 2.1: hydrogen; sodium acetate; acetic acid / palladium 10% on activated carbon / 1471.14 - 2206.72 Torr View Scheme | |
Multi-step reaction with 3 steps 1: thionyl chloride / 1,2-dichloro-benzene; N,N-dimethyl-formamide / 42 °C 2: aluminum (III) chloride / 0.5 h / Cooling with ice 3: hydrogen; sodium acetate; palladium 10% on activated carbon / methanol / 2 h / 40 °C / 2205.22 - 3675.37 Torr View Scheme |
ethyl 3-(6,7-dibromo-2,3-dihydro-1-benzofuran-5-yl)propanoate
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 93 percent / aq. KOH / ethanol / 1 h / 90 °C 2: SOCl2 / 75 °C 3: AlCl3 / 1,2-dichloro-ethane / 20 °C 4: 89 percent / AcOH; H2 / 10percent Pd/C/H2O / 1 h / 20 °C View Scheme |
6-hydroxy-7-(2-mesyloxyethyl)indan-1-one
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With triethylamine In ethyl acetate for 3h; Reflux; | 4.47 g |
formaldehyd
1-(dihydrobenzofuran-4-yl)ethanone
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
Stage #1: formaldehyd; 1-(dihydrobenzofuran-4-yl)ethanone With dicyclohexylammonium trifloroacetate In 1,4-dioxane at 100℃; for 4h; Stage #2: With sulfuric acid In pentane at 67℃; Inert atmosphere; |
6-hydroxy-1-indanone
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1.1: potassium carbonate / acetone / 5 h / Reflux 2.1: N,N-dimethyl-aniline / Inert atmosphere; Reflux 2.2: 25 °C 3.1: ozone / dichloromethane / -78 - 20 °C / Inert atmosphere 3.2: 20 °C 4.1: toluene-4-sulfonic acid / toluene / 0.75 h / Reflux 5.1: hydrogen / triethylamine; 5% Pd(II)/C(eggshell) / ethanol; tetrahydrofuran / 24 h / 35 °C / 4500.45 - 5250.53 Torr View Scheme |
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: N,N-dimethyl-aniline / Inert atmosphere; Reflux 1.2: 25 °C 2.1: ozone / dichloromethane / -78 - 20 °C / Inert atmosphere 2.2: 20 °C 3.1: toluene-4-sulfonic acid / toluene / 0.75 h / Reflux 4.1: hydrogen / triethylamine; 5% Pd(II)/C(eggshell) / ethanol; tetrahydrofuran / 24 h / 35 °C / 4500.45 - 5250.53 Torr View Scheme |
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: ozone / dichloromethane / -78 - 20 °C / Inert atmosphere 1.2: 20 °C 2.1: toluene-4-sulfonic acid / toluene / 0.75 h / Reflux 3.1: hydrogen / triethylamine; 5% Pd(II)/C(eggshell) / ethanol; tetrahydrofuran / 24 h / 35 °C / 4500.45 - 5250.53 Torr View Scheme |
2-methoxy-1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-one
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: toluene-4-sulfonic acid / toluene / 0.75 h / Reflux 2: hydrogen / triethylamine; 5% Pd(II)/C(eggshell) / ethanol; tetrahydrofuran / 24 h / 35 °C / 4500.45 - 5250.53 Torr View Scheme |
3-(2,3-dihydro-1-benzofuran-5-yl)prop-2-enoic acid
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1.1: thionyl chloride / 0.67 h / 26 - 73 °C / Heating / reflux 2.1: hydrogen / nickel / methanol / 4 h / 50 °C 3.1: bromine; sodium acetate; acetic acid / 14 h / 20 - 28 °C 4.1: thionyl chloride / N,N-dimethyl-formamide / 1,2-dichloro-benzene / 2 h / 28 - 60 °C 4.2: 1 h / -5 - 5 °C 5.1: hydrogen; sodium acetate / raney chloride / methanol / 50 °C View Scheme | |
Multi-step reaction with 4 steps 1.1: sodium hydroxide; hydrogen; ammonium formate / palladium 10% on activated carbon / water / 5 - 6 h / 20 °C 2.1: bromine; sodium acetate; acetic acid / 2 - 3 h / 0 - 45 °C 3.1: thionyl chloride / N,N-dimethyl-formamide / 1 - 2 h / 20 °C 3.2: 1 - 2 h / 0 - 5 °C 4.1: hydrogen; sodium acetate; acetic acid / palladium 10% on activated carbon / 1471.14 - 2206.72 Torr View Scheme |
ethyl 3-(2,3-dihydrobenzofuran-5-yl)acrylate
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: hydrogen / nickel / methanol / 4 h / 50 °C 2.1: bromine; sodium acetate; acetic acid / 14 h / 20 - 28 °C 3.1: thionyl chloride / N,N-dimethyl-formamide / 1,2-dichloro-benzene / 2 h / 28 - 60 °C 3.2: 1 h / -5 - 5 °C 4.1: hydrogen; sodium acetate / raney chloride / methanol / 50 °C View Scheme |
3-(2,3-dihydro-1-benzofuran-5-yl)propanoic acid
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: bromine; sodium acetate; acetic acid / 2 - 3 h / 0 - 45 °C 2.1: thionyl chloride / N,N-dimethyl-formamide / 1 - 2 h / 20 °C 2.2: 1 - 2 h / 0 - 5 °C 3.1: hydrogen; sodium acetate; acetic acid / palladium 10% on activated carbon / 1471.14 - 2206.72 Torr View Scheme |
2,3-dihydro-1-benzofuran-4-carbaldehyde
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: tetrahydrofuran / 6.5 h / -10 - 20 °C 2: Dess-Martin periodane / dichloromethane / 2 h / 20 °C 3: copper(II) bis(trifluoromethanesulfonate) / 1,2-dichloro-ethane / 16 h / 10 - 20 °C View Scheme |
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
2,6,7,8-tetrahydro-1H-indeno[5,4-b]furan-8-ol
Conditions | Yield |
---|---|
With sodium tetrahydroborate In tetrahydrofuran; methanol at 0 - 20℃; for 6h; | 100% |
4-chlorobenzaldehyde
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; for 0.366667h; Green chemistry; | 98% |
2-chloro-6-fluorobenzaldehyde
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; for 0.166667h; Green chemistry; | 98% |
With sodium hydroxide In water |
2-chloro-benzaldehyde
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; for 0.333333h; Green chemistry; | 97% |
With sodium hydroxide In water |
2,3-dichlorobenzylaldehyde
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; for 0.483333h; Green chemistry; | 96% |
3,4-dichlorobenzaldehyde
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; for 0.6h; Green chemistry; | 96% |
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With potassium tert-butylate In 1,2-dimethoxyethane; ethanol at 0 - 60℃; for 18h; | 95% |
1-naphthaldehyde
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; for 0.516667h; Green chemistry; | 95% |
2,4-dichlorobenzaldeyhde
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; for 0.583333h; Green chemistry; | 95% |
benzaldehyde
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; for 0.5h; Reagent/catalyst; Green chemistry; | 94% |
With sodium hydroxide In water |
2,6-dichlorobenzaldehyde
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; for 0.583333h; Green chemistry; | 94% |
With sodium hydroxide In water |
cyanoacetic acid
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
2-(1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)acetonitrile
Conditions | Yield |
---|---|
With piperidine at 100 - 110℃; | 93% |
3,4-dimethoxy-benzaldehyde
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; for 0.666667h; Green chemistry; | 93% |
(4-isopropylbenzaldehyde)
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; for 0.5h; Green chemistry; | 91% |
Cyclopropanecarboxaldehyde
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; for 0.416667h; Green chemistry; | 90% |
Conditions | Yield |
---|---|
With ammonium acetate; acetic acid In toluene Reagent/catalyst; Solvent; | 89.8% |
diethyl 1-cyanomethylphosphonate
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
2-(1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-ylidene)acetonitrile
Conditions | Yield |
---|---|
Stage #1: diethyl 1-cyanomethylphosphonate With sodium hydride In tetrahydrofuran; mineral oil at 20℃; for 0.5h; Horner-Wadsworth-Emmons olefination; Stage #2: 1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one In tetrahydrofuran; mineral oil at 40℃; for 1h; Horner-Wadsworth-Emmons olefination; | 89% |
Stage #1: diethyl 1-cyanomethylphosphonate With sodium methylate In tetrahydrofuran at 20℃; for 1h; Stage #2: 1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one In tetrahydrofuran at 20℃; for 2.25h; | 80% |
Stage #1: diethyl 1-cyanomethylphosphonate With sodium hydride In tetrahydrofuran at 25℃; for 1h; Large scale; Stage #2: 1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one In tetrahydrofuran; water for 3.5h; Large scale; | 5.1 kg |
In methanol at 20℃; for 0.25h; Alkaline conditions; | |
With sodium methylate at 5 - 25℃; |
diethyl 1-cyanomethylphosphonate
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
(E)-(1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-ylidene)acetonitrile
Conditions | Yield |
---|---|
With sodium methylate In methanol; water; toluene | 88% |
With sodium methylate In methanol; toluene at 20℃; Wittig Reaction; | 88% |
With sodium methylate In methanol; toluene at 0℃; for 5h; | 84.4% |
p-trifluoromethoxybenzaldehyde
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; for 0.333333h; Green chemistry; | 86% |
3-Cyanobenzaldehyde
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; for 0.666667h; Green chemistry; | 85% |
4-Trifluoromethylbenzaldehyde
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; for 0.383333h; Green chemistry; | 83% |
diethoxyphosphoryl-acetic acid ethyl ester
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
ethyl (2)-1,2,6,7-tetrahydro-8H-indeno[5,4-b]furan-8-ylideneacetate
Conditions | Yield |
---|---|
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In toluene at 0 - 5℃; for 2h; Stage #2: 1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one In toluene at 90 - 100℃; for 15 - 18h; | 80% |
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In toluene; mineral oil at 0 - 20℃; Inert atmosphere; Stage #2: 1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one In toluene; mineral oil at 90 - 100℃; Inert atmosphere; |
[bromo(difluoro)methyl](trimethyl)silane
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
Stage #1: [bromo(difluoro)methyl]-trimethyl-silane; 1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one With tetrabutylammomium bromide In toluene at 110℃; for 7h; Sealed tube; Stage #2: With tetrabutyl ammonium fluoride In toluene at 20℃; for 2h; | 80% |
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
3-Fluorobenzaldehyde
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; for 0.433333h; Green chemistry; | 80% |
2-chloro-3-quinoline carboxaldehyde
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
With sodium hydroxide In water at 20℃; for 0.3h; Green chemistry; | 75% |
diethoxyphosphoryl-acetic acid ethyl ester
1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one
Conditions | Yield |
---|---|
Stage #1: diethoxyphosphoryl-acetic acid ethyl ester With sodium hydride In toluene at 20℃; for 2h; Cooling with ice; Stage #2: 1,2,6,7-tetrahydro-8H-indeno[5,4-b]-furan-8-one In toluene at 90℃; Cooling with ice; | 74% |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View