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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Manufacturer/High quality/Best price/In stock

Cas:204205-33-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-Bromo-2-(2-Fluorophenyl)-1-Cyclopropylethanone supplier in China

Cas:204205-33-4

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product description: Product name 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone CAS number 204205-33-4 Assay ≥90% Appearance Yellowish or off-brown liquid Capacity 50mt/year

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Cas:204205-33-4

Min.Order:100 Gram

FOB Price: $45.0

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Cas:204205-33-4

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Cas 204205-33-4 High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:Off-white powder Package:100g/foil bag;1kg/foil bag;25kg/dr

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-Bromo-2-(2-Fluorophenyl)-1-Cyclopropylethanone

Cas:204205-33-4

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Oled CAS 204205-33-4 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Cas:204205-33-4

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

ANQING CHICO PHARMACEUTICAL CO.,LTD.

High quality. Factory supply. In stock. Best price.1.Quick response within 24 hours;2.Best quality in your requirement;?3.We pay more attention on delivery time, and usually ship on time;4.Under the premise of safety and effectiveness, we can produce

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Cas:204205-33-4

Min.Order:0

Negotiable

Type:Trading Company

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Cas:204205-33-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Win-Win chemical Co.Ltd

Stock products, own laboratory Appearance:Oil to Low-Melting Solid Storage:under inert gas (nitrogen or Argon) at 2-8°C Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:shanghai

Cas no.204205-33-4 98% 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Cas:204205-33-4

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

Competitive Price High Quality Fast Delivery custom-made Welcome to Henan Tianfu Chemical Co., Ltd. website. Our company engages in Sodium Tripolyphosphate (STPP) and Sodium Hexametabphosphate (SHMP) production; development of noble me

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone 204205-33-4

Cas:204205-33-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Cas:204205-33-4

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 204205-33-4 with competitive price

Cas:204205-33-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Factory Supply High Quality CAS 204205-33-4 ,2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Cas:204205-33-4

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White crystalline granules or powder. Storage:Store in seale

99% Prasugrel Intermediate CAS NO. 204205-33-4

Cas:204205-33-4

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone 204205-33-4

Cas:204205-33-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Beluga chemical professional supply 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone 1. Beluga Chemical has a professional RESEARCH and development team and strong technical force to ensure technical support and research capabilities. 2. Made in

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Cas:204205-33-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Cas:204205-33-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Synonyms: Prasugrel Intermediate 4;2-Bromo-2-(2-fluorophenyl);Ethanone, 2-bromo-1-cyclopropyl-2-(2-fluorophenyl)-;2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone;Cylopropylcarbonyl-

Prasugrel intermediate 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Manufactory best quality

Cas:204205-33-4

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

Product name: Prasugrel intermediate Other name: 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone CAS: 204205-33-4 Stock: Fresh Purity: not less than 90% Standard: In-house Package:25kg drum Application:Prasugrel intermediate

Prasugrel supplier

Cas:204205-33-4

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Triumph International Development Limilted

Appearance:yellowish or off-brown liquid Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common produc

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Cas:204205-33-4

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Cas:204205-33-4

Min.Order:1 Kilogram

FOB Price: $1.0 / 100000.0

Type:Lab/Research institutions

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

We are concentrating on APIs and pharmaceutical intermediates. With in depth knowledge and understanding in this industry, we are indulged in supplying a wide assortments of pharmaceutical intermediates from Wuhan, Hubei, China. It is made ob

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Cas:204205-33-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2-bromo-2-(2-fluorophenyl) -1-cyclopropyl ethyl ketone

Cas:204205-33-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Cas:204205-33-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2-Bromo-2-(2-Fluorophenyl)-1-Cyclopropylethanone

Cas:204205-33-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Cas:204205-33-4

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:Colorless to pale yellow transparent liquid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:For

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone

Cas:204205-33-4

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone Manufacturer/High quality/Best price/In stock

Cas:204205-33-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

1)quick response within 12 hours; 2)quality guarantee: all products are strictly tested by our qc, confirmed by qa and approved by third party lab in china, usa, canada, germany, uk, italy, france etc. 3) oem/odm available; 4) rea

2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanoneCAS NO.: 204205-33-4

Cas:204205-33-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Synthetic route

1-cyclopropyl-2-(2-fluorophenyl)ethanone
150322-73-9

1-cyclopropyl-2-(2-fluorophenyl)ethanone

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

Conditions
ConditionsYield
With iodine(I) bromide; 1-n-butyl-3-methylimidazolim bromide In tetrahydrofuran at 40℃; for 4h; Temperature; Time; Concentration;95.3%
With bromine In methanol at 25 - 30℃; for 6h; Concentration;94.65%
With 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; 2,2'-azobis(isobutyronitrile) In cyclohexane at 10℃; Product distribution / selectivity; Reflux;93.28%
(2-fluorophenyl)acetic acid
451-82-1

(2-fluorophenyl)acetic acid

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: triethylamine / dichloromethane / 0.25 h / 0 - 5 °C
1.2: 6 h / 0 - 5 °C
2.1: iodine; magnesium / tetrahydrofuran / 25 - 50 °C
2.2: 40 - 50 °C
2.3: 0.25 h / 0 - 30 °C
3.1: toluene-4-sulfonic acid; 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide / chloroform / 4 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1.1: magnesium; isopropyl bromide / toluene; tetrahydrofuran / 15 - 65 °C
1.2: 5 - 65 °C
2.1: dibenzoyl peroxide; N-Bromosuccinimide / ethyl acetate / 25 - 60 °C
View Scheme
Multi-step reaction with 2 steps
1.1: magnesium; isopropyl bromide / toluene; tetrahydrofuran / 15 - 65 °C
1.2: 5 - 65 °C
2.1: dibenzoyl peroxide; N-Bromosuccinimide / ethyl acetate / 25 - 60 °C
View Scheme
Multi-step reaction with 2 steps
1: sodium hydride / toluene; dimethyl sulfoxide / 1.5 h / 95 - 110 °C / Large scale
2: bromine / methanol / Large scale
View Scheme
2-(2-fluorophenyl)-N-methoxy-N-methylacetamide
946402-23-9

2-(2-fluorophenyl)-N-methoxy-N-methylacetamide

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: iodine; magnesium / tetrahydrofuran / 25 - 50 °C
1.2: 40 - 50 °C
1.3: 0.25 h / 0 - 30 °C
2.1: toluene-4-sulfonic acid; 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide / chloroform / 4 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1.1: iodine; magnesium / tetrahydrofuran / 40 - 50 °C
1.2: 0.25 h / 0 - 30 °C
2.1: 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide / toluene-4-sulfonic acid / dichloromethane / 4.75 h / 0 - 5 °C / Reflux
View Scheme
2-fluorobenzyl chloride
345-35-7

2-fluorobenzyl chloride

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: tetrabutylammomium bromide / dichloromethane; water / 25 °C
2.1: sodium hydroxide; water / 5 - 95 °C
2.2: pH 2 - 3
3.1: magnesium; isopropyl bromide / toluene; tetrahydrofuran / 15 - 65 °C
3.2: 5 - 65 °C
4.1: dibenzoyl peroxide; N-Bromosuccinimide / ethyl acetate / 25 - 60 °C
View Scheme
Multi-step reaction with 4 steps
1.1: tetrabutylammomium bromide / dichloromethane; water / 25 °C
2.1: sodium hydroxide; water / 5 - 95 °C
2.2: pH 2 - 3
3.1: magnesium; isopropyl bromide / toluene; tetrahydrofuran / 15 - 65 °C
3.2: 5 - 65 °C
4.1: dibenzoyl peroxide; N-Bromosuccinimide / ethyl acetate / 25 - 60 °C
View Scheme
Multi-step reaction with 2 steps
1: magnesium; iodine / tetrahydrofuran; 2-methyltetrahydrofuran / 1.5 h / 40 - 45 °C / Inert atmosphere
2: N-Bromosuccinimide; toluene-4-sulfonic acid / acetonitrile / 24 h / 40 °C
View Scheme
Multi-step reaction with 2 steps
1: magnesium; iodine / tetrahydrofuran; toluene / 1.5 h / 40 - 45 °C / Inert atmosphere
2: N-Bromosuccinimide; toluene-4-sulfonic acid / acetonitrile / 24 h / 40 °C
View Scheme
2-fluorophenyl acetonitrile
326-62-5

2-fluorophenyl acetonitrile

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sodium hydroxide; water / 5 - 95 °C
1.2: pH 2 - 3
2.1: magnesium; isopropyl bromide / toluene; tetrahydrofuran / 15 - 65 °C
2.2: 5 - 65 °C
3.1: dibenzoyl peroxide; N-Bromosuccinimide / ethyl acetate / 25 - 60 °C
View Scheme
Multi-step reaction with 3 steps
1.1: sodium hydroxide; water / 5 - 95 °C
1.2: pH 2 - 3
2.1: magnesium; isopropyl bromide / toluene; tetrahydrofuran / 15 - 65 °C
2.2: 5 - 65 °C
3.1: dibenzoyl peroxide; N-Bromosuccinimide / ethyl acetate / 25 - 60 °C
View Scheme
ethyl cyclopropylcarboxylate
4606-07-9

ethyl cyclopropylcarboxylate

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

Conditions
ConditionsYield
Stage #1: With iodine; magnesium; isopropyl bromide In tetrahydrofuran at 65℃; for 3h;
Stage #2: ethyl cyclopropylcarboxylate In tetrahydrofuran at 5 - 70℃; for 3.16667h;
Stage #3: With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); toluene-4-sulfonic acid In chloroform at 28 - 65℃; for 4h;
2-(2-fluorophenyl acetic acid)

2-(2-fluorophenyl acetic acid)

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: triethylamine / dicyclohexyl-carbodiimide; benzotriazol-1-ol / dichloromethane / 6 h / 0 - 5 °C
2.1: iodine; magnesium / tetrahydrofuran / 40 - 50 °C
2.2: 0.25 h / 0 - 30 °C
3.1: 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide / toluene-4-sulfonic acid / dichloromethane / 4.75 h / 0 - 5 °C / Reflux
View Scheme
fluorobenzene
462-06-6

fluorobenzene

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: tin(IV) chloride / tetrahydrofuran / 4 h / 45 °C
2: dichloromethane / 4 h / 20 °C
3: bromine / tetrahydrofuran / 10 h / 20 °C
View Scheme
methyl o-fluorophenylacetate
57486-67-6

methyl o-fluorophenylacetate

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: pyridine / tetrahydrofuran / 6 h / 20 - 60 °C
2: 2,2'-azobis(isobutyronitrile); N-Bromosuccinimide / chloroform / 8 h / 20 °C
View Scheme
o-fluorobenzyl bromide
446-48-0

o-fluorobenzyl bromide

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: magnesium / methyl iodide / diethyl ether / 20 °C
1.2: 20 °C
1.3: 0 °C
2.1: 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; 2,2'-azobis(isobutyronitrile) / cyclohexane / 10 °C / Reflux
View Scheme
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

5,6,7,7a-tetrahydro-thieno[3,2-c]pyridin-2(4H)-one hydrochloride
115473-15-9

5,6,7,7a-tetrahydro-thieno[3,2-c]pyridin-2(4H)-one hydrochloride

5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one
150322-38-6

5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one

Conditions
ConditionsYield
With ammonium bicarbonate In dichloromethane at 5 - 20℃;98%
With copper(l) iodide; sodium carbonate; XPhos In 1,4-dioxane at 60℃; for 3h; Reagent/catalyst; Temperature; Inert atmosphere;90.2%
With potassium phosphate; iodine In 1,4-dioxane at 80℃; for 4h; Temperature; Time; Reagent/catalyst;87.6%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

N-allyl isothiocyanate
57-06-7

N-allyl isothiocyanate

4-aminoethylbenzene
589-16-2

4-aminoethylbenzene

3-allyl-2-(4'-ethylphenylimino)-4-cyclopropyl-5-(2'-fluorophenyl)-thiazole

3-allyl-2-(4'-ethylphenylimino)-4-cyclopropyl-5-(2'-fluorophenyl)-thiazole

Conditions
ConditionsYield
With polyvinyl pyridine (PVP) In ethanol at 20℃; for 18h; regioselective reaction;96%
With 1-octyl-3-methylimidazole hexafluorophosphate at 20℃; for 1h; regioselective reaction;96%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

2-[1-(2-naphthenyl)ethyledene]hydrazinecarbothioamide
133477-39-1

2-[1-(2-naphthenyl)ethyledene]hydrazinecarbothioamide

4-cyclopropyl-5-(2-fluorophenyl)-2-((1-(naphthalen-2-yl)ethylidene)hydrazono)-2,3-dihydrothiazole

4-cyclopropyl-5-(2-fluorophenyl)-2-((1-(naphthalen-2-yl)ethylidene)hydrazono)-2,3-dihydrothiazole

Conditions
ConditionsYield
With triethylamine In ethanol for 0.333333h; Hantzsch Thiazole Synthesis; Reflux;96%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

p-toluidine
106-49-0

p-toluidine

N-allyl isothiocyanate
57-06-7

N-allyl isothiocyanate

3-allyl-2-(4'-methylphenylimino)-4-cyclopropyl-5-(2'-fluorophenyl)-thiazole

3-allyl-2-(4'-methylphenylimino)-4-cyclopropyl-5-(2'-fluorophenyl)-thiazole

Conditions
ConditionsYield
With polyvinyl pyridine (PVP) In ethanol at 20℃; for 20h; Reagent/catalyst; Temperature; Time; regioselective reaction;95%
With 1-octyl-3-methylimidazole hexafluorophosphate at 20℃; for 1h; regioselective reaction;95%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

4-Ethoxyaniline
156-43-4

4-Ethoxyaniline

N-allyl isothiocyanate
57-06-7

N-allyl isothiocyanate

3-allyl-2-(4'-ethoxylphenylimino)-4-cyclopropyl-5-(2'-fluorophenyl)-thiazole

3-allyl-2-(4'-ethoxylphenylimino)-4-cyclopropyl-5-(2'-fluorophenyl)-thiazole

Conditions
ConditionsYield
With polyvinyl pyridine (PVP) In ethanol at 20℃; for 14h; regioselective reaction;95%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

6-methoxy-tetral-4-one thiosemicarbazone
304458-95-5

6-methoxy-tetral-4-one thiosemicarbazone

4-cyclopropyl-5-(2-fluorophenyl)-2-((6-methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)hydrazono)-2,3-dihydrothiazole

4-cyclopropyl-5-(2-fluorophenyl)-2-((6-methoxy-3,4-dihydronaphthalen-1(2H)-ylidene)hydrazono)-2,3-dihydrothiazole

Conditions
ConditionsYield
With triethylamine In ethanol for 0.5h; Reagent/catalyst; Solvent; Temperature; Hantzsch Thiazole Synthesis; Reflux;95%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

4-Ethoxyaniline
156-43-4

4-Ethoxyaniline

N-allyl isothiocyanate
57-06-7

N-allyl isothiocyanate

3-allyl-2-(4'-ethoxylphenylimino)-4-cyclopropyl-5-(2'-fluoro-phenyl)-thiazole

3-allyl-2-(4'-ethoxylphenylimino)-4-cyclopropyl-5-(2'-fluoro-phenyl)-thiazole

Conditions
ConditionsYield
With 1-octyl-3-methylimidazole hexafluorophosphate at 20℃; for 0.75h; regioselective reaction;95%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

2-(3,4-dihydronaphthalen-1(2H)-ylidene)hydrazinecarbothioamide
3689-17-6

2-(3,4-dihydronaphthalen-1(2H)-ylidene)hydrazinecarbothioamide

4-cyclopropyl-2-((3,4-dihydronaphthalen-1(2H)-ylidene)hydrazono)-5-(2-fluorophenyl)-2,3-dihydrothiazole

4-cyclopropyl-2-((3,4-dihydronaphthalen-1(2H)-ylidene)hydrazono)-5-(2-fluorophenyl)-2,3-dihydrothiazole

Conditions
ConditionsYield
With triethylamine In ethanol for 0.5h; Hantzsch Thiazole Synthesis; Reflux;94%
4-HYDROXYPIPERIDINE
5382-16-1

4-HYDROXYPIPERIDINE

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

1-(α-cyclopropylcarbonyl-2-fluorobenzyl)-4-hydroxypiperidine

1-(α-cyclopropylcarbonyl-2-fluorobenzyl)-4-hydroxypiperidine

Conditions
ConditionsYield
With potassium carbonate In N-methyl-acetamide; water93%
With potassium carbonate In N-methyl-acetamide; water93%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

(5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)boronic acid
1263407-24-4

(5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl)boronic acid

Conditions
ConditionsYield
Stage #1: C7H10BNO2S*C7H8O3S With triethylamine In ethanol at 50℃; Inert atmosphere;
Stage #2: 2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone In ethanol at 50℃; for 8h;
93%

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

3-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)thiazolidine-2,4-dione
1563931-94-1

3-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)thiazolidine-2,4-dione

Conditions
ConditionsYield
With sodium hydrogencarbonate In N,N-dimethyl-formamide at 20℃; for 6h;93%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

4-methoxy-aniline
104-94-9

4-methoxy-aniline

methyl thioisocyanate
556-61-6

methyl thioisocyanate

3-methyl-2-(4'-methoxyphenylimino)-4-cyclopropyl-5-(2'-fluorophenyl)-thiazole

3-methyl-2-(4'-methoxyphenylimino)-4-cyclopropyl-5-(2'-fluorophenyl)-thiazole

Conditions
ConditionsYield
With polyvinyl pyridine (PVP) In ethanol at 20℃; for 16h; regioselective reaction;93%
With 1-octyl-3-methylimidazole hexafluorophosphate at 20℃; for 1.5h; regioselective reaction;93%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

1-indanone thiosemicarbazone
74227-66-0

1-indanone thiosemicarbazone

4-cyclopropyl-2-((2,3-dihydro-1H-inden-1-ylidene)hydrazono)-5-(2-fluorophenyl)-2,3-dihydrothiazole

4-cyclopropyl-2-((2,3-dihydro-1H-inden-1-ylidene)hydrazono)-5-(2-fluorophenyl)-2,3-dihydrothiazole

Conditions
ConditionsYield
With triethylamine In ethanol for 0.333333h; Hantzsch Thiazole Synthesis; Reflux;93%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

Ethyl isothiocyanate
542-85-8

Ethyl isothiocyanate

4-aminoethylbenzene
589-16-2

4-aminoethylbenzene

3-ethyl-2-(4'-ethylphenylimino)-4-cyclopropyl-5-(2'-fluorophenyl)-thiazole

3-ethyl-2-(4'-ethylphenylimino)-4-cyclopropyl-5-(2'-fluorophenyl)-thiazole

Conditions
ConditionsYield
With polyvinyl pyridine (PVP) In ethanol at 20℃; for 14h; regioselective reaction;92%
With 1-octyl-3-methylimidazole hexafluorophosphate at 20℃; for 1.5h; regioselective reaction;92%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

Ethyl isothiocyanate
542-85-8

Ethyl isothiocyanate

4-Ethoxyaniline
156-43-4

4-Ethoxyaniline

3-ethyl-2-(4'-ethoxyphenylimino)-4-cyclopropyl-5-(2'-fluoro-phenyl)-thiazole

3-ethyl-2-(4'-ethoxyphenylimino)-4-cyclopropyl-5-(2'-fluoro-phenyl)-thiazole

Conditions
ConditionsYield
With polyvinyl pyridine (PVP) In ethanol at 20℃; for 12h; regioselective reaction;91%
With 1-octyl-3-methylimidazole hexafluorophosphate at 20℃; for 2h; regioselective reaction;91%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

1-(1-(4-methoxyphenyl)ethylidene)thiosemicarbazide
16546-08-0

1-(1-(4-methoxyphenyl)ethylidene)thiosemicarbazide

4-cyclopropyl-5-(2-fluorophenyl)-2-(2-(1-(4-methoxyphenyl)ethylidene)hydrazinyl)thiazole

4-cyclopropyl-5-(2-fluorophenyl)-2-(2-(1-(4-methoxyphenyl)ethylidene)hydrazinyl)thiazole

Conditions
ConditionsYield
With triethylamine In ethanol for 0.583333h; Hantzsch Thiazole Synthesis; Reflux;91%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

5,6,7,7a-tetrahydrothieno[3,2-c]pyridine-2(4H)-one monohydrochloride
109904-37-2

5,6,7,7a-tetrahydrothieno[3,2-c]pyridine-2(4H)-one monohydrochloride

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

2-(tert-butyldimethylsilyloxy)-5-(α-cyclopropylformyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
952340-38-4

2-(tert-butyldimethylsilyloxy)-5-(α-cyclopropylformyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine

Conditions
ConditionsYield
Stage #1: 5,6,7,7a-tetrahydrothieno[3,2-c]pyridine-2(4H)-one monohydrochloride With triethylamine In dichloromethane at 10℃; for 0.25h;
Stage #2: tert-butyldimethylsilyl chloride In dichloromethane at 10℃;
Stage #3: 2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone With triethylamine; sodium iodide In dichloromethane at 10 - 25℃; Temperature;
90%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

1-(1-(3,4-dimethoxyphenyl)ethylidene)thiosemicarbazide
71173-46-1

1-(1-(3,4-dimethoxyphenyl)ethylidene)thiosemicarbazide

4-cyclopropyl-2-((1-(3,4-dimethoxyphenyl)ethylidene)hydrazono)-5-(2-fluorophenyl)-2,3-dihydrothiazole

4-cyclopropyl-2-((1-(3,4-dimethoxyphenyl)ethylidene)hydrazono)-5-(2-fluorophenyl)-2,3-dihydrothiazole

Conditions
ConditionsYield
With triethylamine In ethanol for 0.666667h; Hantzsch Thiazole Synthesis; Reflux;90%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

4-methoxy-aniline
104-94-9

4-methoxy-aniline

N-allyl isothiocyanate
57-06-7

N-allyl isothiocyanate

3-allyl-2-(4'-methoxyphenylimino)-4-cyclopropyl-5-(2'-fluorophenyl)-thiazole

3-allyl-2-(4'-methoxyphenylimino)-4-cyclopropyl-5-(2'-fluorophenyl)-thiazole

Conditions
ConditionsYield
With polyvinyl pyridine (PVP) In ethanol at 20℃; for 16h; regioselective reaction;89%
With 1-octyl-3-methylimidazole hexafluorophosphate at 20℃; for 0.75h; regioselective reaction;89%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

2-(1-(4-tolyl)ethylidene)hydrazinecarbothioamide
7410-54-0

2-(1-(4-tolyl)ethylidene)hydrazinecarbothioamide

4-cyclopropyl-5-(2-fluorophenyl)-2-((1-(p-tolyl)ethylidene)hydrazono)-2,3-dihydrothiazole

4-cyclopropyl-5-(2-fluorophenyl)-2-((1-(p-tolyl)ethylidene)hydrazono)-2,3-dihydrothiazole

Conditions
ConditionsYield
With triethylamine In ethanol for 0.583333h; Hantzsch Thiazole Synthesis; Reflux;89%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

4-bromo-aniline
106-40-1

4-bromo-aniline

N-allyl isothiocyanate
57-06-7

N-allyl isothiocyanate

3-allyl-2-(4'-bromophenylimino)-4-cyclopropyl-5-(2'-fluorophenyl)-thiazole

3-allyl-2-(4'-bromophenylimino)-4-cyclopropyl-5-(2'-fluorophenyl)-thiazole

Conditions
ConditionsYield
With polyvinyl pyridine (PVP) In ethanol at 20℃; for 20h; regioselective reaction;88%
With 1-octyl-3-methylimidazole hexafluorophosphate at 20℃; for 1.25h; regioselective reaction;88%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

2-[1-(4-nitrophenyl)ethylidene]hydrazine-1-carbothioamide
5424-45-3

2-[1-(4-nitrophenyl)ethylidene]hydrazine-1-carbothioamide

4-cyclopropyl-5-(2-fluorophenyl)-2-((1-(4-nitrophenyl)ethylidene)hydrazono)-2,3-dihydrothiazole

4-cyclopropyl-5-(2-fluorophenyl)-2-((1-(4-nitrophenyl)ethylidene)hydrazono)-2,3-dihydrothiazole

Conditions
ConditionsYield
With triethylamine In ethanol for 0.5h; Hantzsch Thiazole Synthesis; Reflux;88%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

C8H14BrNO2S

C8H14BrNO2S

C19H23BrFNO3S

C19H23BrFNO3S

Conditions
ConditionsYield
With potassium phosphate; iodine at 80℃; for 7h; Temperature; Reagent/catalyst;87.1%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

m-Anisidine
536-90-3

m-Anisidine

N-allyl isothiocyanate
57-06-7

N-allyl isothiocyanate

3-allyl-2-(3'-methoxyphenylimino)-4-cyclopropyl-5-(2'-fluoro-phenyl)-thiazole

3-allyl-2-(3'-methoxyphenylimino)-4-cyclopropyl-5-(2'-fluoro-phenyl)-thiazole

Conditions
ConditionsYield
With polyvinyl pyridine (PVP) In ethanol at 20℃; for 18h; regioselective reaction;87%
With 1-octyl-3-methylimidazole hexafluorophosphate at 20℃; for 1h; regioselective reaction;87%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

4-chloro-aniline
106-47-8

4-chloro-aniline

N-allyl isothiocyanate
57-06-7

N-allyl isothiocyanate

3-allyl-2-(4'-chlorophenylimino)-4-cyclopropyl-5-(2'-fluorophenyl)-thiazole

3-allyl-2-(4'-chlorophenylimino)-4-cyclopropyl-5-(2'-fluorophenyl)-thiazole

Conditions
ConditionsYield
With polyvinyl pyridine (PVP) In ethanol at 20℃; for 20h; regioselective reaction;87%
With 1-octyl-3-methylimidazole hexafluorophosphate at 20℃; for 1.25h; regioselective reaction;87%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

4-amino-phenol
123-30-8

4-amino-phenol

N-allyl isothiocyanate
57-06-7

N-allyl isothiocyanate

3-allyl-2-(4'-hydroxyphenylimino)-4-cyclopropyl-5-(2'-fluorophenyl)-thiazole

3-allyl-2-(4'-hydroxyphenylimino)-4-cyclopropyl-5-(2'-fluorophenyl)-thiazole

Conditions
ConditionsYield
With polyvinyl pyridine (PVP) In ethanol at 20℃; for 24h; regioselective reaction;82%
With 1-octyl-3-methylimidazole hexafluorophosphate at 20℃; for 1h; regioselective reaction;82%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

(E)-4-(acetylsulfanyl)-3-((1-[(2-pyridyl)methyl]-1H-pyrazol-3-yl)methylidene)piperidine bis(hydrogen trifluoroacetate)

(E)-4-(acetylsulfanyl)-3-((1-[(2-pyridyl)methyl]-1H-pyrazol-3-yl)methylidene)piperidine bis(hydrogen trifluoroacetate)

(E)-4-(acetylsulfanyl)-1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-3-((1-[(2-pyridyl)methyl]-1H-pyrazol-3-yl)methylidene)piperidine

(E)-4-(acetylsulfanyl)-1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-3-((1-[(2-pyridyl)methyl]-1H-pyrazol-3-yl)methylidene)piperidine

Conditions
ConditionsYield
With triethylamine In acetonitrile at 20℃; for 0.5h;81%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

(E)-4-(acetylsulfanyl)-3-((1-[3-(ethoxycarbonyl)propyl]-1H-1,2,3-triazol-4-yl)methylidene)piperidine hydrogen trifluoroacetate
853805-52-4

(E)-4-(acetylsulfanyl)-3-((1-[3-(ethoxycarbonyl)propyl]-1H-1,2,3-triazol-4-yl)methylidene)piperidine hydrogen trifluoroacetate

(E)-4-(acetylsulfanyl)-1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-3-((1-[3-(ethoxycarbonyl)propyl]-1H-1,2,3-triazol-4-yl)methylidene)piperidine

(E)-4-(acetylsulfanyl)-1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-3-((1-[3-(ethoxycarbonyl)propyl]-1H-1,2,3-triazol-4-yl)methylidene)piperidine

Conditions
ConditionsYield
With triethylamine In acetonitrile at 20℃; for 2.5h;77%
2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone
204205-33-4

2-bromo-1-cyclopropyl-2-(2-fluorophenyl)ethanone

(E)-3-[(furan-2-yl)methylidene]piperidin-4-ol hydrogen acetate

(E)-3-[(furan-2-yl)methylidene]piperidin-4-ol hydrogen acetate

(E)-1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-3-[(furan-2-yl)methylidene]piperidin-4-ol

(E)-1-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-3-[(furan-2-yl)methylidene]piperidin-4-ol

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 0 - 20℃; for 1h;74%
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