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Kono Chem Co.,Ltd

About us We are a Professionally Managed Biotech Company exclusively into the manufacturing, Marketing and Exporting of Plant Extracts and Health Care Products.There are 15 experts in our research team. We insi

Beta-Ecdysone Hydroxyecdysone 5289-74-7

Cas:5289-74-7

Min.Order:1 Kilogram

FOB Price: $600.0

Type:Other

inquiry

Hubei Vanz Pharm Co.,Ltd

ISO/factory/goodquality 1. high quality 2.fast delivery 3, stable stock 4. ISO factory and bulk production Appearance:off white Storage:Dry,cool place Package:drum Application:active pharmaceutical ingredients Transportation:by air/sea/expre

Lonwin Chemical Group Limited

Why Choose Us 1. Quality Price We are the manufacturer, so we can provide the competitive price and high quality product. 2. Packing Products could be packaged according to customer's specializedrequirements. 3. Transport The products can be tr

ShangHai Soyoung Biotechnology Inc

Trade Assurance Get full protection for your orders 100% Product quality protection 100% On-time shipment protection 100% Payment protection Appearance:White powder Storage:Store in a cool dry place, avoiding sunlight directly Package:aluminium foil

Cyanotis Arachnoisea Extract Powder 50%-98% Ecdysterone

Cas:5289-74-7

Min.Order:5 Kilogram

FOB Price: $2160.0

Type:Lab/Research institutions

inquiry

Nanjing Spring & Autumn Biological Engineering Co., Ltd.

Nanjing Spring & Autumn Biological Engineering Co., Ltd. Which was founded at 2008, has an R & D team composed very experienced natural products chemists. The company is a high-tech enterprise engaged in functional health care products raw ma

Hydroxyecdysone

Cas:5289-74-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Greenutra Resource Inc

Cyanotis Arachnoisea Extract 95% beta Ecdysterone CAS NO.:5289-74-7 Latin Name:Cyanotis arachinoidea CB Clarke Molecular Weight:480.64 Molecular Formula:C27H44O7 Quality data Identification

Cyanotis Arachnoisea Extract 95% beta Ecdysterone

Cas:5289-74-7

Min.Order:1 Kilogram

FOB Price: $15.0

Type:Trading Company

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

factory supply 98% Hydroxyecdysone Ecdysone Extract β-ecdysone

Cas:5289-74-7

Min.Order:1 Kilogram

FOB Price: $175.0 / 550.0

Type:Trading Company

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Hydroxyecdysone supplier in China

Cas:5289-74-7

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co., LTD is a professional research, development and production 2-phenylacetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low carbon environ

Beta-Ecdysone or Hydroxyecdysone

Cas:5289-74-7

Min.Order:100 Gram

FOB Price: $2.0

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Factory supply Hydroxyecdysone CAS 5289-74-7 with reasonable price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed ad

Factory supply Hydroxyecdysone CAS 5289-74-7 with reasonable price

Cas:5289-74-7

Min.Order:1 Gram

FOB Price: $10.0

Type:Trading Company

inquiry

Xi'an Quanao Biotech Co., Ltd.

Building Healthy Life Professional Factory We has a complete production and operating system, with an annual output capacity of 2000 tons. It can produce variety of content and proportion of extract according to the demand . Appearance:Brown yell

Promote The Synthesis Of Collagen Arachnoid Cyanotis Root Extract Beta Ecdysone Powder

Cas:5289-74-7

Min.Order:1 Kilogram

FOB Price: $370.0 / 2459.0

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Appearance:white powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

beta-Ecdysone

Cas:5289-74-7

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Hydroxyecdysone

Cas:5289-74-7

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Hydroxyecdysone 5289-74-7 GMP manufacturer

Cas:5289-74-7

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

5289-74-7 - Physico-chemical Properties Molecular Formula C27H44O7 Molar Mass 480.64 Density 1.0760 (rough estimate) Melting Point 242-244°C Boling Point 498.63°C (rough estimate)

Factory high quality Hydroxyecdysone

Cas:5289-74-7

Min.Order:1 Gram

FOB Price: $159.0 / 170.0

Type:Lab/Research institutions

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Hydroxyecdysone

Cas:5289-74-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name: Ecdysterone The alias:exahydroxycholest-7-en-6-one;2BETA,3BETA, CAS NO:5289-74-7 EINECS NO:811-097-1 Molecular formula:C27H44O7 Molecular weight:480.63406 Product Quality 12 years of chemical raw materials Mature operation of the

Ecdysterone /CAS:5289-74-7/ China High quality

Cas:5289-74-7

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

20-hydroxyecdysterone 5289-74-7 Hydroxyecdysone

Cas:5289-74-7

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 5289-74-7 with best quality

Cas:5289-74-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Hot Sell Factory Supply Raw Material Ecdysterone 98% CAS NO.5289-74-7

Cas:5289-74-7

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

Hydroxyecdysone CAS5289-74-7

Cas:5289-74-7

Min.Order:1 Kilogram

FOB Price: $289.0 / 499.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product name Beta Ecdysterone CAS 5289-74-7 MF C27H44O7 MW 480.64 Appearance: white powder Storage:Store in cool and dry place, away from sun light. Package: 25kgs/drum Application:Health Food Tra

Beta Ecdysterone

Cas:5289-74-7

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

Our Adwantage: 1.We have stock so we can delivery quickly at the very day when receive the payment. 2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order. 3.High quality gua

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

20-Hydroxyecdysone 5289-74-7

Cas:5289-74-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Hangzhou Fonlynn Health Technology Co., Ltd.

Packing: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Appearance:white powder/ Refer to COA Storage:Refer to COA

5289-74-7 cas 3604-87-3 BETA-ECDYSONE Hydroxyecdysone 90%-98% Ecdysone

Cas:5289-74-7

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hubei CuiRan Biotechnology Co., Ltd

Hubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medicine)

Hydroxyecdysone

Cas:5289-74-7

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present,

Hydroxyecdysone WITH BEST PRICE

Cas:5289-74-7

Min.Order:1 Gram

FOB Price: $700.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Hydroxyecdysone CAS: 5289-74-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermedi

Hydroxyecdysone CAS: 5289-74-7

Cas:5289-74-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Hydroxyecdysone

Cas:5289-74-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

(8R,20R,22R)-2β,3β,20,22,25-pentahydroxy-8,13-cyclo-13,14-seco-5β-cholestane-6,14-dione

(8R,20R,22R)-2β,3β,20,22,25-pentahydroxy-8,13-cyclo-13,14-seco-5β-cholestane-6,14-dione

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
ConditionsYield
With sodium hydroxide In methanol for 2.5h; Heating;89%
14alpha-Hydroperoxy-20-hydroxyecdysone
115040-67-0

14alpha-Hydroperoxy-20-hydroxyecdysone

A

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

B

(8R,20R,22R)-2β,3β,20,22,25-pentahydroxy-8,13-cyclo-13,14-seco-5β-cholestane-6,14-dione

(8R,20R,22R)-2β,3β,20,22,25-pentahydroxy-8,13-cyclo-13,14-seco-5β-cholestane-6,14-dione

Conditions
ConditionsYield
With iron(II) sulfate In tetrahydrofuran; water Ambient temperature; pH=3;A 5%
B 85%
(2S,3R,5R,9R,10R,13R,14S,17S)-14-Hydroxy-17-((1R,2R)-5-hydroxy-1,2-diisopropoxy-1,5-dimethyl-hexyl)-2,3-diisopropoxy-10,13-dimethyl-1,2,3,4,5,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-6-one

(2S,3R,5R,9R,10R,13R,14S,17S)-14-Hydroxy-17-((1R,2R)-5-hydroxy-1,2-diisopropoxy-1,5-dimethyl-hexyl)-2,3-diisopropoxy-10,13-dimethyl-1,2,3,4,5,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-6-one

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
ConditionsYield
With lithium In tetrahydrofuran; ammonia for 1h;82%
(20R,22R)-22-hydroxy-2β,3β,14,20,25-pentakis-(trimethyl-silanyloxy)-5β-cholest-7-en-6-one
135024-06-5

(20R,22R)-22-hydroxy-2β,3β,14,20,25-pentakis-(trimethyl-silanyloxy)-5β-cholest-7-en-6-one

A

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

B

(20R,22S)-2β,3β,14,20,22,25-hexahydro-5β-cholest-7-en-6-one
123238-67-5

(20R,22S)-2β,3β,14,20,22,25-hexahydro-5β-cholest-7-en-6-one

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃;A 80%
B n/a
22-Dehydro-20-hydroxyecdysone
19974-12-0

22-Dehydro-20-hydroxyecdysone

A

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

B

(20R,22S)-2β,3β,14,20,22,25-hexahydro-5β-cholest-7-en-6-one
123238-67-5

(20R,22S)-2β,3β,14,20,22,25-hexahydro-5β-cholest-7-en-6-one

Conditions
ConditionsYield
With lithium tri-t-butoxyaluminum hydride In tetrahydrofuran 1) -78 deg C, 3h, 2) 20 deg C, 1h;A 6%
B 68%
Yield given. Yields of byproduct given;
With lithium tri-t-butoxyaluminum hydride Yield given. Multistep reaction. Yields of byproduct given;
Turkesterone
41451-87-0

Turkesterone

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
ConditionsYield
With sodium nitrite; palladium on activated charcoal In ethanol; water under 760 Torr; for 1h;67%
(20R,22R)-2β,3β,14α,25-tetrahydroxy-20,22-(butan-2-yl)boranediyldioxy-5β-cholest-7-en-6-one
1450761-60-0

(20R,22R)-2β,3β,14α,25-tetrahydroxy-20,22-(butan-2-yl)boranediyldioxy-5β-cholest-7-en-6-one

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
ConditionsYield
With dihydrogen peroxide In tetrahydrofuran; water for 0.166667h;58%
(20R,22R)-6-ethoxy-5β-cholesta-6,8(14)-diene-2β,3β,20,22,25-pentol

(20R,22R)-6-ethoxy-5β-cholesta-6,8(14)-diene-2β,3β,20,22,25-pentol

A

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

B

14alpha-Hydroperoxy-20-hydroxyecdysone
115040-67-0

14alpha-Hydroperoxy-20-hydroxyecdysone

Conditions
ConditionsYield
With oxalic acid In methanol for 6h; Ambient temperature; darkness;A 9%
B 57%
2,3-didehydro-2,3-dideoxy-20-hydroxyecdysone
1373335-50-2

2,3-didehydro-2,3-dideoxy-20-hydroxyecdysone

A

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

B

2,3-di-epi-20-hydroxyαecdysone

2,3-di-epi-20-hydroxyαecdysone

Conditions
ConditionsYield
With pyridine; osmium(VIII) oxideA 54%
B 32%
20-hydroxyecdysone-2,3,22-triacetate
19404-87-6, 84507-62-0

20-hydroxyecdysone-2,3,22-triacetate

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
ConditionsYield
With potassium hydroxide In methanol Heating;
(20R,22R)-2β,3β,14,20,22,25-hexakis-(trimethylsilanyloxy)-5β-cholest-7-en-6-one
54289-60-0

(20R,22R)-2β,3β,14,20,22,25-hexakis-(trimethylsilanyloxy)-5β-cholest-7-en-6-one

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
ConditionsYield
Yield given. Multistep reaction;
2,22-dideoxyecdysone
41408-38-2

2,22-dideoxyecdysone

A

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

B

ecdysone
3604-87-3

ecdysone

C

22-Deoxyecdysone
34209-85-3

22-Deoxyecdysone

Conditions
ConditionsYield
With Locusta migratoria at 33℃; for 6h; Product distribution; tissue distr. of C22 hydroxylase;
ecdysterone 20-O-benzoate
114317-60-1

ecdysterone 20-O-benzoate

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
ConditionsYield
With potassium hydrogencarbonate In methanol; water at 20 - 38℃; for 204h;7 mg
Sileneoside B
84699-93-4

Sileneoside B

A

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

B

ecdysterone 22-O-α-D-galactopyranoside
81655-86-9

ecdysterone 22-O-α-D-galactopyranoside

Conditions
ConditionsYield
In water at 27℃; for 528h; galactosidase;A 10 mg
B 7 mg
14alpha-Hydroperoxy-20-hydroxyecdysone
115040-67-0

14alpha-Hydroperoxy-20-hydroxyecdysone

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
ConditionsYield
With dimethylsulfide In dichloromethane Ambient temperature; Yield given;
Acetic acid (2S,3R,5R,9R,10R,13R,14S,17S)-3-acetoxy-17-((S)-1,5-dihydroxy-1,5-dimethyl-hexyl)-14-hydroxy-10,13-dimethyl-6-oxo-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-2-yl ester

Acetic acid (2S,3R,5R,9R,10R,13R,14S,17S)-3-acetoxy-17-((S)-1,5-dihydroxy-1,5-dimethyl-hexyl)-14-hydroxy-10,13-dimethyl-6-oxo-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-2-yl ester

A

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

B

Taxisterone

Taxisterone

Conditions
ConditionsYield
With potassium carbonate In methanol for 0.5h; Ambient temperature;A n/a
B 11 mg
(2S,3R,5R,9R,10R,13R,14S,17S)-10,13-Dimethyl-17-((1R,2R)-1,2,5-trihydroxy-1,5-dimethyl-hexyl)-1,2,3,4,5,6,9,10,11,12,13,15,16,17-tetradecahydro-cyclopenta[a]phenanthrene-2,3,6,14-tetraol
69841-30-1

(2S,3R,5R,9R,10R,13R,14S,17S)-10,13-Dimethyl-17-((1R,2R)-1,2,5-trihydroxy-1,5-dimethyl-hexyl)-1,2,3,4,5,6,9,10,11,12,13,15,16,17-tetradecahydro-cyclopenta[a]phenanthrene-2,3,6,14-tetraol

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
ConditionsYield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In 1,4-dioxane
Multi-step reaction with 2 steps
1: O2 / Pt / H2O
2: NaBH4 / ethanol; tetrahydrofuran
View Scheme
Conditions
ConditionsYield
With sodium tetrahydroborate In tetrahydrofuran; ethanol
ecdysone
3604-87-3

ecdysone

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
ConditionsYield
With ecdysone 20-monooxygenase; oxygen; NADPH hydroxylation catalyzed by ecdysone 20-monooxygenase; other reagents;
20-hydroxyecdysone 3-O-α-D-galactoside
93552-68-2

20-hydroxyecdysone 3-O-α-D-galactoside

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
ConditionsYield
With almond enzymes; water at 36℃; for 720h; Hydrolysis; Enzymatic reaction;
ecdysone
3604-87-3

ecdysone

A

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

B

3-epi-26-hydroxyecdysone
75319-59-4

3-epi-26-hydroxyecdysone

C

26-hydroxyecdysone
52717-49-4

26-hydroxyecdysone

E

3-epi-20,26-dihydroxyecdysone
71939-17-8

3-epi-20,26-dihydroxyecdysone

F

20,26-dihydroxyecdysone
19458-46-9

20,26-dihydroxyecdysone

G

4 polar acidic metabolites

4 polar acidic metabolites

Conditions
ConditionsYield
metabolism after injection into Pieris brassicae (Lepidoptera) pharate pupae, 3H labeled study;

A

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

B

inokosterone
88980-54-5

inokosterone

C

25-deoxy-20-hydroxyecdyson-26-oic acid
59971-16-3

25-deoxy-20-hydroxyecdyson-26-oic acid

D

20-hydroxyecdyson-26-oic acid
86583-58-6

20-hydroxyecdyson-26-oic acid

E

20,26-dihydroxyecdysone
19458-46-9

20,26-dihydroxyecdysone

F

very polar products (VVP), conjugates (C)

very polar products (VVP), conjugates (C)

Conditions
ConditionsYield
With air; D-glucose; epidermis of premolt crab Carcinus maenas L; penicillin G; 2-amino-2-hydroxymethyl-1,3-propanediol; monophenylthiourea In water at 20℃; for 48h; Mechanism; different metabolism after incubation of various tissues or injection in intermolt and premolt crabs (Carcinus maenas L.), 3H labeled studies;
26-hydroxyecdysone
52717-49-4

26-hydroxyecdysone

A

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

B

ecdysone
3604-87-3

ecdysone

C

3-epi-26-hydroxyecdysone
75319-59-4

3-epi-26-hydroxyecdysone

E

3-epi-20,26-dihydroxyecdysone
71939-17-8

3-epi-20,26-dihydroxyecdysone

F

20,26-dihydroxyecdysone
19458-46-9

20,26-dihydroxyecdysone

G

4 polar acidic metabolites

4 polar acidic metabolites

Conditions
ConditionsYield
metabolism after injection into Pieris brassicae (Lepidoptera) pharate pupae, 3H labeled study;
[2β-2H]cholesterol
54594-70-6

[2β-2H]cholesterol

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
ConditionsYield
With Tween 80; hairy roots of Ajuga reptans var. atropurpurea In methanol; chloroform; acetone hydroxylation; Irradiation;6.0 mg
20-Hydroxyecdysone-3-beta-D-glucopyranoside
128365-93-5

20-Hydroxyecdysone-3-beta-D-glucopyranoside

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
ConditionsYield
With hydrogenchloride In methanol for 4h; Heating;
6β-hydroxy-5α-cholest-2-ene
27948-74-9

6β-hydroxy-5α-cholest-2-ene

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
ConditionsYield
Multi-step reaction with 10 steps
1: 83 percent / p-TsOH*H2O / CH2Cl2 / 0.5 h / 20 °C
2: 80 percent / m-chloroperbenzoic acid; Na2CO3 / CH2Cl2 / 0.5 h / 20 °C
3: 93 percent / LiAlD4 / tetrahydrofuran / 0.5 h / 60 °C
4: pyridinium chlorochromate; NaOAc; molecular sieves 4 Angstroem / CH2Cl2 / 0.17 h / 20 °C
5: LiAlH4 / tetrahydrofuran / 0.33 h / 20 °C
6: pyridine / 20 °C
7: 2 N aq. HCl / methanol; tetrahydrofuran / 6 h / 20 °C
8: POCl3; pyridine / 3 h / 20 °C
9: KOH / methanol; tetrahydrofuran / 20 °C
10: 6.0 mg / hairy roots of Ajuga reptans var. atropurpurea; Tween 80 / acetone; CHCl3; methanol / Irradiation
View Scheme
C29H47(2)HO2
264925-89-5

C29H47(2)HO2

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: KOH / methanol; tetrahydrofuran / 20 °C
2: 6.0 mg / hairy roots of Ajuga reptans var. atropurpurea; Tween 80 / acetone; CHCl3; methanol / Irradiation
View Scheme
2-[(5S,6R,8S,9S,10R,13R,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-6-yloxy]-tetrahydro-pyran
264925-82-8

2-[(5S,6R,8S,9S,10R,13R,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-6-yloxy]-tetrahydro-pyran

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1: 80 percent / m-chloroperbenzoic acid; Na2CO3 / CH2Cl2 / 0.5 h / 20 °C
2: 93 percent / LiAlD4 / tetrahydrofuran / 0.5 h / 60 °C
3: pyridinium chlorochromate; NaOAc; molecular sieves 4 Angstroem / CH2Cl2 / 0.17 h / 20 °C
4: LiAlH4 / tetrahydrofuran / 0.33 h / 20 °C
5: pyridine / 20 °C
6: 2 N aq. HCl / methanol; tetrahydrofuran / 6 h / 20 °C
7: POCl3; pyridine / 3 h / 20 °C
8: KOH / methanol; tetrahydrofuran / 20 °C
9: 6.0 mg / hairy roots of Ajuga reptans var. atropurpurea; Tween 80 / acetone; CHCl3; methanol / Irradiation
View Scheme
[2β-2H]-5α-cholestane-3β,6β-diol 3-acetate
264925-88-4

[2β-2H]-5α-cholestane-3β,6β-diol 3-acetate

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: POCl3; pyridine / 3 h / 20 °C
2: KOH / methanol; tetrahydrofuran / 20 °C
3: 6.0 mg / hairy roots of Ajuga reptans var. atropurpurea; Tween 80 / acetone; CHCl3; methanol / Irradiation
View Scheme
(2R,3S,5S,6R,8S,9S,10R,13R,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-10,13-dimethyl-6-(tetrahydro-pyran-2-yloxy)-hexadecahydro-20-oxa-cyclopropa[2,3]cyclopenta[a]phenanthrene
264925-83-9

(2R,3S,5S,6R,8S,9S,10R,13R,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-10,13-dimethyl-6-(tetrahydro-pyran-2-yloxy)-hexadecahydro-20-oxa-cyclopropa[2,3]cyclopenta[a]phenanthrene

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
ConditionsYield
Multi-step reaction with 8 steps
1: 93 percent / LiAlD4 / tetrahydrofuran / 0.5 h / 60 °C
2: pyridinium chlorochromate; NaOAc; molecular sieves 4 Angstroem / CH2Cl2 / 0.17 h / 20 °C
3: LiAlH4 / tetrahydrofuran / 0.33 h / 20 °C
4: pyridine / 20 °C
5: 2 N aq. HCl / methanol; tetrahydrofuran / 6 h / 20 °C
6: POCl3; pyridine / 3 h / 20 °C
7: KOH / methanol; tetrahydrofuran / 20 °C
8: 6.0 mg / hairy roots of Ajuga reptans var. atropurpurea; Tween 80 / acetone; CHCl3; methanol / Irradiation
View Scheme
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

acetone
67-64-1

acetone

20-hydroxyecdysone 2,3:20,22-diacetonide
84507-66-4, 22798-98-7

20-hydroxyecdysone 2,3:20,22-diacetonide

Conditions
ConditionsYield
With (1S)-10-camphorsulfonic acid at 25℃; Inert atmosphere;97%
With toluene-4-sulfonic acid Cyclization;85%
With phosphomolybdic acid at 25℃; for 0.583333h;82%
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

acetone
67-64-1

acetone

20-hydroxyecdysone 20,22-acetonide
84507-68-6, 22798-96-5

20-hydroxyecdysone 20,22-acetonide

Conditions
ConditionsYield
With tetrafluoroboric acid at 25℃; for 0.166667h;97%
With toluene-4-sulfonic acid93%
With toluene-4-sulfonic acid In methanol89%
With phosphomolybdic acid In methanol at 20℃; for 0.166667h;45.43%
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

(20R,22R)-2β,3β,14α,20,22,25-hexahydroxy-7,8α-dihydro-5β-cholestan-6-one

(20R,22R)-2β,3β,14α,20,22,25-hexahydroxy-7,8α-dihydro-5β-cholestan-6-one

Conditions
ConditionsYield
With sodium nitrite; palladium on activated charcoal In ethanol; water under 760 Torr; for 3h;96%
With palladium 10% on activated carbon; hydrogen; sodium In methanol at 20℃; for 3h;91%
With lithium aluminium tetrahydride In diethyl ether at 20℃; for 0.5h;21%
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

14alpha-Hydroperoxy-20-hydroxyecdysone
115040-67-0

14alpha-Hydroperoxy-20-hydroxyecdysone

Conditions
ConditionsYield
With hydrogenchloride In tetrahydrofuran for 6h; Ambient temperature;95%
Multi-step reaction with 2 steps
1: ammonia; lithium / tetrahydrofuran / 0.5 h / -33 °C
2: oxygen
View Scheme
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

(trifluoromethyl)trimethylsilane
81290-20-2

(trifluoromethyl)trimethylsilane

(20R,22R)-2β,3β,14,20,22,25-hexakis-(trimethylsilanyloxy)-5β-cholest-7-en-6-one
54289-60-0

(20R,22R)-2β,3β,14,20,22,25-hexakis-(trimethylsilanyloxy)-5β-cholest-7-en-6-one

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran for 0.05h;95%
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

propargyl bromide
106-96-7

propargyl bromide

(20R,22R)-2β,3β,20,22,25-pentahydroxy-7,7-bis(2-propyn-1-yl)-5β-cholest-8(14)-en-6-one

(20R,22R)-2β,3β,20,22,25-pentahydroxy-7,7-bis(2-propyn-1-yl)-5β-cholest-8(14)-en-6-one

Conditions
ConditionsYield
Stage #1: 20-Hydroxyecdysone With ammonia; lithium In tetrahydrofuran at -33℃; for 0.5h; Inert atmosphere;
Stage #2: propargyl bromide In tetrahydrofuran at 20℃; for 24h; Inert atmosphere;
94%
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

acetone
67-64-1

acetone

A

20-hydroxyecdysone 20,22-acetonide
84507-68-6, 22798-96-5

20-hydroxyecdysone 20,22-acetonide

B

20-hydroxyecdysone 2,3:20,22-diacetonide
84507-66-4, 22798-98-7

20-hydroxyecdysone 2,3:20,22-diacetonide

Conditions
ConditionsYield
With toluene-4-sulfonic acid In methanol for 1h;A 93%
B 2%
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

cyclohexanone
108-94-1

cyclohexanone

20-hydroxyecdysone 2,3;20,22-di(cyclohexylacetal)

20-hydroxyecdysone 2,3;20,22-di(cyclohexylacetal)

Conditions
ConditionsYield
With (1S)-10-camphorsulfonic acid at 25℃; Inert atmosphere;93%
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

propargyl bromide
106-96-7

propargyl bromide

(20R,22R)-2β,3β,20,22,25-pentahydroxy-7α-(2-propyn-1-yl)-5β-cholest-8(14)-en-6-one

(20R,22R)-2β,3β,20,22,25-pentahydroxy-7α-(2-propyn-1-yl)-5β-cholest-8(14)-en-6-one

Conditions
ConditionsYield
Stage #1: 20-Hydroxyecdysone With lithium In tetrahydrofuran at -33℃; for 0.5h; Inert atmosphere;
Stage #2: propargyl bromide In tetrahydrofuran at 20℃; for 12h; Inert atmosphere;
92%
vinyl acetate
108-05-4

vinyl acetate

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

20-Hydroxyecdysone-2-acetate
19536-25-5

20-Hydroxyecdysone-2-acetate

Conditions
ConditionsYield
In pyridine; tert-Amyl alcohol at 45℃; for 168h; Candida antarctica lipase B supported on acrylic resin (Novozym 435);90%
With pyridine; lipase In tert-Amyl alcohol at 45℃; Product distribution / selectivity;
With pyridine; lipase In acetonitrile at 45℃; Product distribution / selectivity;
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

acetaldehyde
75-07-0

acetaldehyde

20,22-O-[(1RS)-ethylidene]-20-hydroxyecdysone

20,22-O-[(1RS)-ethylidene]-20-hydroxyecdysone

Conditions
ConditionsYield
With phosphomolybdic acid at 25℃; for 0.5h;90%
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

acetaldehyde
75-07-0

acetaldehyde

2,3:20,22-bis-O-[(1R)-ethylidene]-20-hydroxyecdysone

2,3:20,22-bis-O-[(1R)-ethylidene]-20-hydroxyecdysone

Conditions
ConditionsYield
Stage #1: 20-Hydroxyecdysone; acetaldehyde at 2℃; for 72h;
Stage #2: With phosphomolybdic acid at 25℃; for 0.166667h;
88%
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

benzoyl chloride
98-88-4

benzoyl chloride

20-hydroxyecdysone 2,3,22-tribenzoate

20-hydroxyecdysone 2,3,22-tribenzoate

Conditions
ConditionsYield
With pyridine at 0 - 20℃; Inert atmosphere;87%
trimethylsilyl trifluoromethanesulfonate
27607-77-8

trimethylsilyl trifluoromethanesulfonate

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

(20R,22R)-2β,3β,14,20,22,25-hexakis-(trimethylsilanyloxy)-5β-cholest-7-en-6-one
54289-60-0

(20R,22R)-2β,3β,14,20,22,25-hexakis-(trimethylsilanyloxy)-5β-cholest-7-en-6-one

Conditions
ConditionsYield
With 2,6-dimethylpyridine In tetrahydrofuran at 20℃;86%
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

14,15-anhydro-20-hydroxyecdysone (6Z)-oxime

14,15-anhydro-20-hydroxyecdysone (6Z)-oxime

Conditions
ConditionsYield
Stage #1: 20-Hydroxyecdysone With hydroxylamine hydrochloride In pyridine at 70℃; for 72h;
Stage #2: With potassium hydroxide In ethanol
Stage #3: With phosphomolybdic acid In methanol for 1h;
86%
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

trifluoroacetic anhydride
407-25-0

trifluoroacetic anhydride

20,22-O-(1-hydroxy-2,2,2-trifluoromethylethylidene)-20-hydroxyecdysone

20,22-O-(1-hydroxy-2,2,2-trifluoromethylethylidene)-20-hydroxyecdysone

Conditions
ConditionsYield
In chloroform at 25℃; for 24h;85%
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Cinnamoyl chloride
102-92-1

Cinnamoyl chloride

20-hydroxyecdysone 2,22-dicinnamate

20-hydroxyecdysone 2,22-dicinnamate

Conditions
ConditionsYield
With pyridine at 0 - 20℃; Inert atmosphere;85%
indole-3-acetic acid
87-51-4

indole-3-acetic acid

20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

20-hydroxyecdysone 2,3,22-tri(2-(1H-indol-3-yl)acetate)

20-hydroxyecdysone 2,3,22-tri(2-(1H-indol-3-yl)acetate)

Conditions
ConditionsYield
Stage #1: indole-3-acetic acid With dicyclohexyl-carbodiimide In 1,4-dioxane for 1h; Inert atmosphere;
Stage #2: 20-Hydroxyecdysone With dmap In 1,4-dioxane at 40℃; for 22h; Inert atmosphere;
83%
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

methyl iodide
74-88-4

methyl iodide

A

(20R,22R)-2β,3β,20,22,25-pentahydroxy-7α-methyl-5β-cholest-8(14)-en-6-one

(20R,22R)-2β,3β,20,22,25-pentahydroxy-7α-methyl-5β-cholest-8(14)-en-6-one

B

(20R,22R)-7α-methyl-2β-methoxy-3β,20,22,25-tetrahydroxy-5β-cholest-8(14)-en-6-one

(20R,22R)-7α-methyl-2β-methoxy-3β,20,22,25-tetrahydroxy-5β-cholest-8(14)-en-6-one

C

(20R,22R)-7α-methyl-3β-methoxy-2β,20,22,25-tetrahydroxy-5β-cholest-8(14)-en-6-one

(20R,22R)-7α-methyl-3β-methoxy-2β,20,22,25-tetrahydroxy-5β-cholest-8(14)-en-6-one

Conditions
ConditionsYield
Stage #1: 20-Hydroxyecdysone With ammonia; lithium In tetrahydrofuran at -33℃; for 0.5h;
Stage #2: methyl iodide In tetrahydrofuran at 20℃; for 24h; stereospecific reaction;
A 82%
B 8%
C 8%
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Conditions
ConditionsYield
With [bis(acetoxy)iodo]benzene In methanol at 20℃; for 0.75h;81.41%
With bis-[(trifluoroacetoxy)iodo]benzene In methanol at 20℃; for 1h;57.8%
With bis-[(trifluoroacetoxy)iodo]benzene57.8%
With chromium(VI) oxide; sulfuric acid In acetone
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

acetic anhydride
108-24-7

acetic anhydride

20-hydroxyecdysone-2,3,22-triacetate
19404-87-6, 84507-62-0

20-hydroxyecdysone-2,3,22-triacetate

Conditions
ConditionsYield
With pyridine at 0 - 20℃; Inert atmosphere;80%
With pyridine at 20℃;34 mg
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

butanone
78-93-3

butanone

A

29α-ethyl-29β-methyl-20,22-O-methylidene-20-hydroxyecdysone

29α-ethyl-29β-methyl-20,22-O-methylidene-20-hydroxyecdysone

B

2,3-O-[(2RS)-butan-2-ylidene]-20,22-O-[(2R)-butan-2-ylidene]-20-hydroxyecdysone

2,3-O-[(2RS)-butan-2-ylidene]-20,22-O-[(2R)-butan-2-ylidene]-20-hydroxyecdysone

Conditions
ConditionsYield
With phosphomolybdic acid at 25℃; for 0.0833333h;A 20%
B 78%
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

Hexanoyl chloride
142-61-0

Hexanoyl chloride

20-hydroxyecdysone 2,22-dihexanoate

20-hydroxyecdysone 2,22-dihexanoate

Conditions
ConditionsYield
With pyridine at 0 - 20℃; Inert atmosphere;77%
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

propargyl bromide
106-96-7

propargyl bromide

A

(20R,22R)-3β,20,22,25-tetrahydroxy-2β-(2-propyn-1-yl)oxy-7,7-bis(2-propyn-1-yl)-5β-cholest-8(14)-en-6-one

(20R,22R)-3β,20,22,25-tetrahydroxy-2β-(2-propyn-1-yl)oxy-7,7-bis(2-propyn-1-yl)-5β-cholest-8(14)-en-6-one

B

(20R,22R)-2β,20,22,25-tetrahydroxy-3β-(2-propyn-1-yl)oxy-7,7-bis(2-propyn-1-yl)-5β-cholest-8(14)-en-6-one

(20R,22R)-2β,20,22,25-tetrahydroxy-3β-(2-propyn-1-yl)oxy-7,7-bis(2-propyn-1-yl)-5β-cholest-8(14)-en-6-one

C

(20R,22R)-2β,3β,20,22,25-pentahydroxy-7,7-bis(2-propyn-1-yl)-5β-cholest-8(14)-en-6-one

(20R,22R)-2β,3β,20,22,25-pentahydroxy-7,7-bis(2-propyn-1-yl)-5β-cholest-8(14)-en-6-one

Conditions
ConditionsYield
Stage #1: 20-Hydroxyecdysone With ammonia; lithium In tetrahydrofuran at -33℃; for 0.5h; Inert atmosphere;
Stage #2: propargyl bromide In tetrahydrofuran at 20℃; for 24h; Inert atmosphere;
A 12%
B 10%
C 75%
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

allyl bromide
106-95-6

allyl bromide

A

(20R,22R)-7α-allyl-2β,3β,20,22,25-pentahydroxy-5β-cholest-8(14)-en-6-one

(20R,22R)-7α-allyl-2β,3β,20,22,25-pentahydroxy-5β-cholest-8(14)-en-6-one

B

(20R,22R)-7α-allyl-2β-allyloxy-2β,20,22,25-tetrahydroxy-5β-cholest-8(14)-en-6-one

(20R,22R)-7α-allyl-2β-allyloxy-2β,20,22,25-tetrahydroxy-5β-cholest-8(14)-en-6-one

C

(20R,22R)-7α-allyl-3β-allyloxy-2β,20,22,25-tetrahydroxy-5β-cholest-8(14)-en-6-one

(20R,22R)-7α-allyl-3β-allyloxy-2β,20,22,25-tetrahydroxy-5β-cholest-8(14)-en-6-one

D

(20R,22R)-7α-allyl-22-allyloxy-2β,3β,20,25-tetrahydroxy-5β-cholest-8(14)-en-6-one

(20R,22R)-7α-allyl-22-allyloxy-2β,3β,20,25-tetrahydroxy-5β-cholest-8(14)-en-6-one

Conditions
ConditionsYield
Stage #1: 20-Hydroxyecdysone With ammonia; lithium In tetrahydrofuran at -33℃; for 0.5h;
Stage #2: allyl bromide In tetrahydrofuran at 20℃; for 24h; stereospecific reaction;
A 72%
B 10%
C 8%
D 7%
20-Hydroxyecdysone
5289-74-7

20-Hydroxyecdysone

2-Methoxybenzoyl chloride
21615-34-9

2-Methoxybenzoyl chloride

2,3,22-O-tri-(o-methoxybenzoyl)-20-hydroxyecdysone

2,3,22-O-tri-(o-methoxybenzoyl)-20-hydroxyecdysone

Conditions
ConditionsYield
With pyridine71.2%
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