Luhan Pharmachem Co., Ltd. owns strong elite professional quality sales force, has the customer base from the US, Europe, Japan, Southeast Asia, Korea, Hong Kong, Taiwan and other countries and regions, the company operates in accordance with the mod
Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:65141-46-0
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:65141-46-0
Min.Order:0 Metric Ton
Negotiable
Type:Manufacturers
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:65141-46-0
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Name: Nicorandil Chinese aliases: N-(2-hydroxyethyl) nicotinamide nitrate; nicotinamide; nicotinamide; 2-(pyridyl-3-formamide) ethyl nitrate; N-[2-nitroethyl] 3-pyridine bonded amide; N-[2-(nitrooxy) ethyl] pyridine-3-formamide; nicotinamide; Eng
Cas:65141-46-0
Min.Order:25 Metric Ton
FOB Price: $2.0 / 3.0
Type:Other
inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
Nicorandil Basic information Product Name: Nicorandil Synonyms: n-[2-(nitroxy)ethyl]-3-pyridinecarboxamide;N-[2-(NITROOXY)ETHYL]-3-PYRIDINECARBOXAMIDE;NICORANDIL;PERISALOL;SIGMART;IKOREL
Cas:65141-46-0
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:65141-46-0
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryAdvantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s
Cas:65141-46-0
Min.Order:10 Gram
Negotiable
Type:Other
inquiry1,In No Less five years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Appearance:White powder Storage:storage in a dr
Cas:65141-46-0
Min.Order:1 Gram
FOB Price: $11.0
Type:Lab/Research institutions
inquiryWe are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery
Cas:65141-46-0
Min.Order:10 Gram
FOB Price: $1.2
Type:Trading Company
inquiryNicorandil CAS:65141-46-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,
Cas:65141-46-0
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C
Cas:65141-46-0
Min.Order:1 Gram
Negotiable
Type:Trading Company
inquiryCompany information: Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in chemical raw materials and chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big custo
Cas:65141-46-0
Min.Order:1 Kilogram
FOB Price: $8.0 / 10.0
Type:Trading Company
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Appearance:white crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:Se
Cas:65141-46-0
Min.Order:100 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Hubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect. Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other
Cas:65141-46-0
Min.Order:1 Kilogram
FOB Price: $3.0 / 5.0
Type:Trading Company
inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Factory direct sales, accept customization. Nicorandil is a vasodilator used for the prophylaxis and treatment of angina. This medication widens blood vessels thus increasing the blood and oxygen flow to the heart. It is not currently available in t
Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff
Our Advantages Production: Advanced chemical equipment with years of experience.Staffs for producing various extract products. Quality Control:A complete set of Testing Professional and Analysis Equipment ensures the Quality Requirements and Speci
Cas:65141-46-0
Min.Order:1 Kilogram
FOB Price: $150.0 / 180.0
Type:Trading Company
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:65141-46-0
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryNicorandil Powder 99% High Quality 65141-46-0 NicorandilAppearance:powder Storage:store in a cool dry place and keep away from strong Package:according to customers' requirements Application:in research Transportation:By air(EMS or EUB or FedEx or TN
Cas:65141-46-0
Min.Order:1 Gram
Negotiable
Type:Other
inquiryN-(2-hydroxyethyl)nicotinamide
N-(2-nitroxyethyl)nicotinamide
Conditions | Yield |
---|---|
With nitric acid; urea; europium(III) trifluoromethanesulfonate at 70℃; for 6h; Schlenk technique; | 86% |
With nitric acid; propionic acid; propionic acid anhydride at 0 - 30℃; for 3.5h; Temperature; | 85.9% |
With nitric acid at -5℃; for 2h; | 40% |
Stage #1: N-(2-hydroxyethyl)nicotinamide With nitric acid; acetic anhydride; acetic acid at 15 - 22℃; Inert atmosphere; Stage #2: With ammonia In water at 5 - 35℃; for 1h; Product distribution / selectivity; |
2-(pyridin-3-yl)-4,5-dihydrooxazole
isopentyl nitrite
N-(2-nitroxyethyl)nicotinamide
Conditions | Yield |
---|---|
In 1,4-dioxane at 100℃; for 5h; | 80% |
2-(pyridin-3-yl)-4,5-dihydrooxazole
N-(2-nitroxyethyl)nicotinamide
Conditions | Yield |
---|---|
With tert.-butylnitrite; oxygen In 1,4-dioxane at 60℃; Sealed tube; Green chemistry; | 73% |
tert.-butylnitrite
2-(pyridin-3-yl)-4,5-dihydrooxazole
N-(2-nitroxyethyl)nicotinamide
Conditions | Yield |
---|---|
In toluene at 100℃; for 5h; | 60% |
pyridine-3-carbonyl chloride hydrochloride
2-nitroxyethylammonium nitrate
N-(2-nitroxyethyl)nicotinamide
Conditions | Yield |
---|---|
With pyridine at 5 - 20℃; Inert atmosphere; | |
Stage #1: pyridine-3-carbonyl chloride hydrochloride; 2-nitroxyethylammonium nitrate With pyridine at 5 - 20℃; Inert atmosphere; Stage #2: With sodium hydrogencarbonate In chloroform |
3-pyridinecarboxylic acid ethyl ester
N-(2-nitroxyethyl)nicotinamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 18 h / 20 - 55 °C 2: nitric acid / 2 h / -5 °C View Scheme |
pyridine-3-carbonitrile
N-(2-nitroxyethyl)nicotinamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: zinc(II) chloride / chlorobenzene / 36 h / Inert atmosphere; Reflux 2: tert.-butylnitrite; oxygen / 1,4-dioxane / 60 °C / Sealed tube; Green chemistry View Scheme |
3-pyridinecarboxaldehyde
N-(2-nitroxyethyl)nicotinamide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: tetra-N-butylammonium tribromide / ethanol / 1 h / 20 °C 2: 1,4-dioxane / 5 h / 100 °C View Scheme |
Conditions | Yield |
---|---|
In water; acetonitrile Solvent; | 95% |
In water at 20℃; for 48h; | 55.9% |
N-(2-nitroxyethyl)nicotinamide
N-(2-nitroxyethyl)isonicotinamide
Conditions | Yield |
---|---|
With conc. HCl In ethanol; water aq. soln. of PdCl2 added to a soln. of equimolar amts. of the ligands ina mixt.of EtOH:H2O (3:1) at 20-30°C; then conc. HCl added to pH 2-2.5; stirred for 2 h; ppt. filtered off, washed with water and EtOH, and dried in air; elem. anal.; | 94% |
potassium tetrachloroplatinate(II)
N-(2-nitroxyethyl)nicotinamide
PtCl2(C8H9N3O4)2
Conditions | Yield |
---|---|
In water ppt. washing (H2O, EtOH, Et2O); elem. anal.; | 92% |
N-(2-nitroxyethyl)nicotinamide
[(NC5H4C(O)NHCH2CH2ONO2)2Rh2(OOCC(CH3)3)4]
Conditions | Yield |
---|---|
In tetrahydrofuran room temperature, pure Ar atmosphere; soln. evapn. to 1/3, crystals filtration off, air drying, recrystn. (THF); elem. anal.; | 90% |
iodomethyl isopropylcarbamate
N-(2-nitroxyethyl)nicotinamide
1-(((isopropylcarbamoyl)oxy)methyl)-3-((2-(nitroxy)ethyl)carbamoyl)pyridine-1-ium iodide
Conditions | Yield |
---|---|
In acetonitrile at 20℃; | 88% |
In acetonitrile at 20℃; | 88% |
N-(2-nitroxyethyl)nicotinamide
N-(2-nitroxyethyl)isonicotinamide
trans-[(2-nitroxyethyl)isonicotinamide-N'][(2-nitroxyethyl)nicotinamide-N]dichloroplatinum(II)
Conditions | Yield |
---|---|
In ethanol; water aq. soln. of Pt complex added to a soln. of equimolar amts. of the ligands in 60% aq. EtOH at 20-30°C; stirred for 11 h; ppt. filtered off, washed with water and EtOH, and dried in air; elem. anal.; | 86% |
iodomethyl diisopropylcarbamate
N-(2-nitroxyethyl)nicotinamide
Conditions | Yield |
---|---|
In acetonitrile at 20℃; | 85% |
N-(2-nitroxyethyl)nicotinamide
Conditions | Yield |
---|---|
In acetonitrile at 20℃; | 84% |
N-(2-nitroxyethyl)nicotinamide
ethoxycarbonyloxymethyl iodide
Conditions | Yield |
---|---|
In acetonitrile at 20℃; | 77% |
N-(2-nitroxyethyl)nicotinamide
1-hydroxy-2-naphthoic acid
Conditions | Yield |
---|---|
In water at 20℃; for 48h; | 75.8% |
N-(2-nitroxyethyl)nicotinamide
copper(ll) bromide
(NC5H4C(O)NHCH2CH2ONO2)2CuBr2
Conditions | Yield |
---|---|
In tetrahydrofuran pure Ar atmosphere, stirring (3 h), volume reduction (30-40°C, 0.1 torr), cooling to 5°C; ppt. washing (CH2Cl2), vacuum drying, recrystn. (2x, THF); elem. anal.; | 70.5% |
N-(2-nitroxyethyl)nicotinamide
[(NC5H4C(O)NHCH2CH2ONO2)2Cu2(OOCC(CH3)3)4]
Conditions | Yield |
---|---|
In tetrahydrofuran; benzene THF soln. of ligand addn. to benzene soln. of Cu-compd., pure Ar atmosphere; volume redn., recrystn. (THF); elem. anal.; | 70% |
isopropyloxycarbonyloxymethyl iodide
N-(2-nitroxyethyl)nicotinamide
Conditions | Yield |
---|---|
In acetonitrile at 20℃; | 60% |
Conditions | Yield |
---|---|
In water at 20℃; for 48h; | 54.7% |
N-(2-nitroxyethyl)nicotinamide
tert-butyl (iodomethyl) carbonate
Conditions | Yield |
---|---|
54% |
Conditions | Yield |
---|---|
In water at 20℃; for 48h; | 42% |
N-(2-nitroxyethyl)nicotinamide
Conditions | Yield |
---|---|
In toluene stirring (20°C, 0.5 h); evapn., extn. (THF/benzene), crystn. (5°C); elem. anal.; | 40% |
N-(2-nitroxyethyl)nicotinamide
Conditions | Yield |
---|---|
In acetonitrile at 20℃; | 35% |
N-(2-nitroxyethyl)nicotinamide
methyl iodide
Conditions | Yield |
---|---|
With triethylamine In N,N-dimethyl-formamide for 336h; pH=7.0 - 9.0; Solvent; Cooling with ice; | 2.25% |
methyl bromide
N-(2-nitroxyethyl)nicotinamide
Conditions | Yield |
---|---|
With triethylamine In N,N-dimethyl-formamide for 240h; pH=7.0 - 9.0; Darkness; | 1.9% |
N-(2-nitroxyethyl)nicotinamide
2-(pyridin-3-yl)-4,5-dihydrooxazole
Conditions | Yield |
---|---|
In sodium hydroxide at 60℃; for 5h; | 60 mg |
at 60℃; for 7h; Rate constant; Mechanism; Thermodynamic data; variation of pH; Δ Eexcit; |
N-(2-nitroxyethyl)nicotinamide
2-aminoethyl nicotinate nitrate
Conditions | Yield |
---|---|
With water at 70℃; for 4h; | 40 mg |
N-(2-nitroxyethyl)nicotinamide
Conditions | Yield |
---|---|
at 70℃; for 72h; Polymerization; |
N-(2-nitroxyethyl)nicotinamide
(nicorandil)Co(μ-OOCCMe3)4Co(nicorandil)
Conditions | Yield |
---|---|
In tetrahydrofuran; toluene THF soln. of ligand addn. to THF soln. of Co-compd., boiling (15 min), solvent complete removal, residue dissoln. in boiling toluene, volume reduction (Ar flow), slow cooling to room temperature; ppt. sepn., washing (hexane), drying (Ar flow, room temperature); |
N-(2-nitroxyethyl)nicotinamide
Conditions | Yield |
---|---|
In water soln. of ligand addn. to soln. of Co-compd., soln. keeping at room temperature (5 d); solvent removal; elem. anal.; |
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