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Jiangsu Huaen Energy Co., Ltd.

Geographical advantages: the processing base is located in Jiangsu Coastal Chemical Industrial Park with convenient transportation, good human, economic and social environment, and huge potential for market development; Technology Advantages: The

M-Trifluoromethylphenol

Cas:98-17-9

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

3-Trifluoromethylphenol Manufacturer/High quality/Best price/In stock

Cas:98-17-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 3-Hydroxybenzotrifluoride supplier in China

Cas:98-17-9

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off white powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

3-Trifluoromethylphenol

Cas:98-17-9

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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EAST CHEMSOURCES LIMITED

3-Aminotrifluorotoluene Product Name: 3-Aminotrifluorotoluene Molecular Weight: -- CAS NO: 98-17-9 EC NO: -- Molecular Formula: --

3-Aminotrifluorotoluene

Cas:98-17-9

Min.Order:1 Kilogram

FOB Price: $2.0 / 3.0

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply α,α,α-trifluoro-m-cresol

Cas:98-17-9

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Oled CAS 98-17-9 3-Trifluoromethylphenol

Cas:98-17-9

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

3-Trifluoromethylphenol

Cas:98-17-9

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-Hydroxybenzotrifluoride

Cas:98-17-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei yanxi chemical co.,LTD.

Hebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car

3-trifluoromethylphenol

Cas:98-17-9

Min.Order:1 Metric Ton

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

top 3-Trifluoromethylphenol

Cas:98-17-9

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

3-Trifluoromethylphenol 98-17-9

Cas:98-17-9

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 98-17-9 with fast shipping

Cas:98-17-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

3-(trifluoromethyl)phenol CAS NO.98-17-9 M.F: C7H5F3O M.W:162.11 Appearance:Colorless to pale yellow liquid Purity:>99% Used for pharmaceutical intermediate Appearance:light yellow oily liquid Storage:Preserve in well-closed, light-resist

3-Trifluoromethylphenol CAS: 98-17-9

Cas:98-17-9

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:Clear yellow liquid Storage:room temperature Package:200kg/drum Application:5-Trifluoromethylphenol, is a versatile buidiling block used for the synthesis of various chemical compounds, including pesticides. It can be utilized for the pr

3-Trifluoromethylphenol with high quality

Cas:98-17-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is

3-Trifluoromethylphenol CAS NO 98-17-9

Cas:98-17-9

Min.Order:1 Kilogram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

3-Trifluoromethylphenol 98-17-9

Cas:98-17-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

3-Trifluoromethylphenol

Cas:98-17-9

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

3-Trifluoromethylphenol CAS:98-17-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic int

3-Trifluoromethylphenol CAS:98-17-9

Cas:98-17-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

3-Trifluoromethylphenol

Cas:98-17-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:98-17-9

Cas:98-17-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Wuhan Zenuo Biological Medicine Technology Co Ltd

Product Name: 3-Trifluoromethylphenol Synonyms: META-HYDROXYBENZOTRIFLUORIDE;3-HYDROXYBENZOTRIFLUORID 99%;PHENOL,3-(TRIFLUOROMETHYL);α,α,α-Trifluoro-m-cresol, 3-Hydroxybenzotrifluoride;3-(Trifluoromethyl) phenol ,98%;3-(Trifluor

3-Trifluoromethylphenol hiqh purity best quality

Cas:98-17-9

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Price, service, company and transport advantage: 1.place of origin china with super quality by reasonable price. 2. it's customers' right to choose the package (ems, dhl, fedex, ups); 3. it's custo

BEST PRICE/3-Trifluoromethylphenol

Cas:98-17-9

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

3-Trifluoromethylphenol

Cas:98-17-9

Min.Order:1 Kilogram

FOB Price: $20.0 / 30.0

Type:Lab/Research institutions

inquiry

Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

3-Trifluoromethylphenol 98-17-9

Cas:98-17-9

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

3-TRIFLUOROMETHYLPHENOL 98-17-9

Cas:98-17-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

3-(Trifluoromethyl)phenol

Cas:98-17-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3-Trifluoromethylphenol

Cas:98-17-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Hope Chem Co., Ltd

1. Product advantages: exquisite appearance and unique functions. 2. Product Advantages: Our products are the best,fast speed ,in large stock 3. High-quality products and thoughtful service are your greatest satisfaction. 4. The product

3-(Trifluoromethyl)phenol

Cas:98-17-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

3-Trifluoromethylphenol

Cas:98-17-9

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Synthetic route

3-trifluoromethylaniline
98-16-8

3-trifluoromethylaniline

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
Stage #1: 3-trifluoromethylaniline With sulfuric acid; sodium nitrite at 5 - 20℃; for 1h;
Stage #2: With water Reflux;
94%
With sulfuric acid; sodium nitrite at 12.5 - 88℃; Temperature; Reagent/catalyst;93.6%
Stage #1: 3-trifluoromethylaniline With sulfuric acid at 83℃; for 1h;
Stage #2: With sodium nitrite In water at -3℃; for 1h;
Stage #3: With sulfuric acid; copper(II) sulfate In water at 125℃; Temperature;
92%
m-trifluoromethylphenyl iodide
401-81-0

m-trifluoromethylphenyl iodide

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With tetra(n-butyl)ammonium hydroxide In water; dimethyl sulfoxide at 165℃; for 0.0833333h; Flow reactor;90%
With copper acetylacetonate; N1-(4-hydroxy-2,6-dimethylphenyl)-N2-(4-hydroxy-3,5-dimethylphenyl)oxalamide; potassium hydroxide In water; dimethyl sulfoxide at 60℃; for 24h; Schlenk technique; Inert atmosphere;90%
With copper(l) iodide; 8-quinolinol; potassium hydroxide In water; dimethyl sulfoxide; tert-butyl alcohol at 100℃; for 48h; Inert atmosphere;88%
(meta-(trifluoromethyl)phenyl)boronic acid
1423-26-3

(meta-(trifluoromethyl)phenyl)boronic acid

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With copper(II) ferrite; water; sodium hydroxide at 40℃; for 24h; Green chemistry;96%
With oxygen; triethylamine In 2-methyltetrahydrofuran at 20℃; under 760.051 Torr; for 24h; Green chemistry;96%
With dihydrogen peroxide In water at 20℃; for 0.166667h; Green chemistry;92%
1-but-3-enoxy-3-(trifluoromethyl)benzene

1-but-3-enoxy-3-(trifluoromethyl)benzene

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With [2,2]bipyridinyl; (1,2-dimethoxyethane)dichloronickel(II); water; bis(pinacol)diborane; lithium tert-butoxide In methanol; N,N-dimethyl acetamide at 30℃; for 24h; Schlenk technique;67%
With 6,6'-dimethyl-2,2'-bipyridine; (1,2-dimethoxyethane)dichloronickel(II); bis(pinacol)diborane; lithium tert-butoxide In methanol; N,N-dimethyl acetamide; water at 30℃; for 24h; Inert atmosphere; Glovebox; Sealed tube;67%
C12H13F3O

C12H13F3O

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With [2,2]bipyridinyl; (1,2-dimethoxyethane)dichloronickel(II); water; bis(pinacol)diborane; lithium tert-butoxide In methanol; N,N-dimethyl acetamide at 30℃; for 24h; Schlenk technique;63%
With 6,6'-dimethyl-2,2'-bipyridine; (1,2-dimethoxyethane)dichloronickel(II); bis(pinacol)diborane; lithium tert-butoxide In methanol; N,N-dimethyl acetamide; water at 30℃; for 24h; Inert atmosphere; Glovebox; Sealed tube;63%
1-(benzyloxy)-3-(trifluoromethyl)benzene
70097-64-2

1-(benzyloxy)-3-(trifluoromethyl)benzene

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With 1-n-butyl-3-methylimidazolim bromide at 200 - 220℃; for 0.0833333h; Microwave irradiation; Inert atmosphere;98%
3-hydroxyphenylboronic acid
87199-18-6

3-hydroxyphenylboronic acid

Umemoto's reagent
129946-88-9

Umemoto's reagent

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With 2,4,6-trimethyl-pyridine; copper diacetate In N,N-dimethyl acetamide at 0℃; under 760.051 Torr; for 16h; Inert atmosphere;60%
meta-trifluoromethylphenyl N,N-diethylcarbamate
1245824-29-6

meta-trifluoromethylphenyl N,N-diethylcarbamate

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With zirconocene dichloride In tetrahydrofuran at 20℃; Inert atmosphere;91%
3-chlorotrifluoromethylbenzene
98-15-7

3-chlorotrifluoromethylbenzene

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With copper acetylacetonate; N1-(4-hydroxy-2,6-dimethylphenyl)-N2-(4-hydroxy-3,5-dimethylphenyl)oxalamide; water In water; dimethyl sulfoxide at 130℃; for 24h; Schlenk technique; Inert atmosphere;93%
With 5-(di-tert-butylphosphino)-1′, 3′, 5′-triphenyl-1′H-[1,4′]bipyrazole; tris-(dibenzylideneacetone)dipalladium(0); cesiumhydroxide monohydrate In tetrahydrofuran at 65℃; Inert atmosphere; Glovebox; Sealed tube;86%
Multi-step reaction with 2 steps
1: 2-methyl-8-hydroxyquinoline copper; sodium hydroxide / methanol / 5 h / 100 - 105 °C / 6000.6 - 7500.75 Torr / Autoclave
2: methanol / 35 - 40 °C / Autoclave
View Scheme
3-trifluoromethyl-2-cyclohexene-1-one
74031-45-1

3-trifluoromethyl-2-cyclohexene-1-one

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With tetrakis(acetonitrile)palladium(II) bis(tetrafluoroborate); 6,6'-dimethyl-2,2'-bipyridine; sodium anthraquinone-2-sulfonate; oxygen In water; dimethyl sulfoxide at 80℃; under 760.051 Torr; for 12h;68%
4-chloro-3-trifluoromethylphenol
6294-93-5

4-chloro-3-trifluoromethylphenol

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With hydrogen In ethanol
With hydrogen In ethanol
(3-trifluoromethylphenyl)(phenyl)iodonium triflate

(3-trifluoromethylphenyl)(phenyl)iodonium triflate

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With dihydrogen peroxide; sodium iodide; sodium hydroxide In methanol at 20℃; for 1h; Microwave irradiation;47%
3-bromo-1-trifluoromethylbenzene
401-78-5

3-bromo-1-trifluoromethylbenzene

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With copper acetylacetonate; N1-(4-hydroxy-2,6-dimethylphenyl)-N2-(4-hydroxy-3,5-dimethylphenyl)oxalamide; water In water; dimethyl sulfoxide at 80℃; for 24h; Schlenk technique; Inert atmosphere;84%
Multi-step reaction with 2 steps
1: 2-methyl-8-hydroxyquinoline copper; sodium hydroxide / methanol / 2 h / 100 - 105 °C / 6000.6 - 7500.75 Torr / Autoclave
2: methanol / 35 - 40 °C / Autoclave
View Scheme
[3-(trifluoromethyl)phenyl](2,4,6-trimethylphenyl)iodonium trifluoromethanesulfonate
1204518-08-0

[3-(trifluoromethyl)phenyl](2,4,6-trimethylphenyl)iodonium trifluoromethanesulfonate

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With water; sodium acetate; copper(l) chloride In N,N-dimethyl-formamide at 40℃; for 2h; Inert atmosphere; Sealed tube;75%
cis-1,2-dihydroxy-3-trifluoromethyl-cyclohexa-3,5-diene
131101-28-5

cis-1,2-dihydroxy-3-trifluoromethyl-cyclohexa-3,5-diene

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With sodium hydroxide In water at 25℃; Kinetics; Concentration;100%
sodium 3-(trifluoromethyl)phenolate

sodium 3-(trifluoromethyl)phenolate

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
In methanol at 35 - 40℃; Autoclave;156.8 g
Conditions
ConditionsYield
With water at 30℃; for 168h; Sealed tube; Irradiation;
α,α,α-trifluorotoluene
98-08-8

α,α,α-trifluorotoluene

A

4-hydroxybenzotrifluoride
402-45-9

4-hydroxybenzotrifluoride

B

2-(trifluoromethyl)phenol
444-30-4

2-(trifluoromethyl)phenol

C

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With tert.-butylnitrite; water; oxygen; 2,3-dicyano-5,6-dichloro-p-benzoquinone In neat (no solvent) at 24.84℃; Inert atmosphere; Irradiation; Overall yield = 8 %;
With oxygen; ascorbic acid In water; acetic acid at 105℃; under 11251.1 Torr; for 11h; Overall yield = 14 %;
Stage #1: α,α,α-trifluorotoluene With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; 2-(t-butylazo)prop-2-yl hydroperoxide In benzene at 44.84℃;
Stage #2: With N,O-Bis(trimethylsilyl)trifluoroacetamide at 75℃; for 2h; Temperature; Solvent; Inert atmosphere; regioselective reaction;

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With bis(benzonitrile)palladium(II) dichloride In benzene for 20h; Heating;93%
3-(trifluoromethyl)anisole
454-90-0

3-(trifluoromethyl)anisole

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With 1-n-butyl-3-methylimidazolim bromide at 220℃; for 1h; Inert atmosphere; Microwave irradiation;94%
3-trifluoromethyl-1-(diethoxymethylsilyl)benzene
1763-87-7

3-trifluoromethyl-1-(diethoxymethylsilyl)benzene

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With potassium fluoride; dihydrogen peroxide In ethanol for 18h; Heating;60%
C7H4F3N2O(1+)*BF4(1-)

C7H4F3N2O(1+)*BF4(1-)

A

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

B

4-fluoro-3-(trifluoromethyl)phenol
61721-07-1

4-fluoro-3-(trifluoromethyl)phenol

Conditions
ConditionsYield
With pyridine; hydrogen fluoride for 3.33333h; Decomposition; Fluoro-dediazoniation; Irradiation;A 0.1%
B 83.8%
With pyridine; hydrogen fluoride at 140℃; Decomposition; Fluoro-dediazoniation;A 1.1%
B 2.5%
4-trifluoromethylphenylamine
455-14-1

4-trifluoromethylphenylamine

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: dichloromethane; water / 1 h / 25 °C
2.1: sulfuric acid; nitric acid / 2 h / 28 °C
3.1: sulfuric acid / 5 h / 80 °C
4.1: sulfuric acid; acetic acid / water / 2 h / 35 °C
4.2: 3 h / -3 °C
5.1: hydrogen; palladium on activated charcoal / methanol / 4 h / 30 °C / 3750.38 - 13501.4 Torr / Autoclave
6.1: sulfuric acid / 1 h / 83 °C
6.2: 1 h / -3 °C
6.3: 125 °C
View Scheme
4-(trifluromethyl)acetanilide
349-97-3

4-(trifluromethyl)acetanilide

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: sulfuric acid; nitric acid / 2 h / 28 °C
2.1: sulfuric acid / 5 h / 80 °C
3.1: sulfuric acid; acetic acid / water / 2 h / 35 °C
3.2: 3 h / -3 °C
4.1: hydrogen; palladium on activated charcoal / methanol / 4 h / 30 °C / 3750.38 - 13501.4 Torr / Autoclave
5.1: sulfuric acid / 1 h / 83 °C
5.2: 1 h / -3 °C
5.3: 125 °C
View Scheme
N-(2-nitro-4-(trifluoromethyl)phenyl)acetamide
396-12-3

N-(2-nitro-4-(trifluoromethyl)phenyl)acetamide

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sulfuric acid / 5 h / 80 °C
2.1: sulfuric acid; acetic acid / water / 2 h / 35 °C
2.2: 3 h / -3 °C
3.1: hydrogen; palladium on activated charcoal / methanol / 4 h / 30 °C / 3750.38 - 13501.4 Torr / Autoclave
4.1: sulfuric acid / 1 h / 83 °C
4.2: 1 h / -3 °C
4.3: 125 °C
View Scheme
4-trifluoromethyl-2-nitroaniline
400-98-6

4-trifluoromethyl-2-nitroaniline

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: sulfuric acid; acetic acid / water / 2 h / 35 °C
1.2: 3 h / -3 °C
2.1: hydrogen; palladium on activated charcoal / methanol / 4 h / 30 °C / 3750.38 - 13501.4 Torr / Autoclave
3.1: sulfuric acid / 1 h / 83 °C
3.2: 1 h / -3 °C
3.3: 125 °C
View Scheme
N-Trifluoromethyl-N-nitrosobenzenesulfonamide
80783-62-6

N-Trifluoromethyl-N-nitrosobenzenesulfonamide

phenol
108-95-2

phenol

A

4-hydroxybenzotrifluoride
402-45-9

4-hydroxybenzotrifluoride

B

2-(trifluoromethyl)phenol
444-30-4

2-(trifluoromethyl)phenol

C

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With dimethylglyoxal In acetonitrile for 5h; Irradiation; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
3-(trifluoromethyl)phenyl 4-methylbenzenesulfonate
131086-40-3

3-(trifluoromethyl)phenyl 4-methylbenzenesulfonate

acetone
67-64-1

acetone

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With bis[chloro(1,2,3-trihapto-allylbenzene)palladium(II)]; N-[2-(di(1-adamantyl)phosphino)phenyl]morpholine; caesium carbonate at 90℃; for 16h; Inert atmosphere; sealed vial;
(4-Nitro-phenyl)-acetic acid 3-trifluoromethyl-phenyl ester
75993-61-2

(4-Nitro-phenyl)-acetic acid 3-trifluoromethyl-phenyl ester

A

4-nitrobenzeneacetic acid
104-03-0

4-nitrobenzeneacetic acid

B

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With barium dihydroxide In water; dimethyl sulfoxide at 30℃; Rate constant; Mechanism;
diazotized 3-amino-trifluoromethyl-benzene

diazotized 3-amino-trifluoromethyl-benzene

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

Conditions
ConditionsYield
With sulfuric acid
3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

methyl iodide
74-88-4

methyl iodide

3-(trifluoromethyl)anisole
454-90-0

3-(trifluoromethyl)anisole

Conditions
ConditionsYield
With potassium carbonate In acetone at 0 - 20℃; for 18h;100%
With potassium carbonate In acetone at 0 - 20℃; for 18h; Inert atmosphere;100%
With sodium hydride In tetrahydrofuran for 12h;80%
3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

3-(trifluoromethyl)phenyl 4-methylbenzenesulfonate
131086-40-3

3-(trifluoromethyl)phenyl 4-methylbenzenesulfonate

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran; water at 0 - 20℃; for 2h; Green chemistry;100%
Stage #1: 3-Trifluoromethylphenol With potassium hydroxide In tetrahydrofuran at 20℃; for 0.0833333h; Inert atmosphere;
Stage #2: p-toluenesulfonyl chloride In tetrahydrofuran at 60℃; Inert atmosphere;
96%
Stage #1: 3-Trifluoromethylphenol With potassium hydroxide In tetrahydrofuran at 20℃; for 0.0833333h; Inert atmosphere;
Stage #2: p-toluenesulfonyl chloride In tetrahydrofuran at 20 - 60℃; Inert atmosphere;
96%
3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

potassium 3-(trifluoromethyl)phenolate
56705-78-3

potassium 3-(trifluoromethyl)phenolate

Conditions
ConditionsYield
With potassium tert-butylate for 0.5h; Inert atmosphere;100%
With potassium tert-butylate for 0.5h;
With potassium tert-butylate for 0.00833333h; Schlenk technique; Inert atmosphere;

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

1-(5-chlorobenzoxazol-2-yl)-1-(3-(trifluoromethyl)phenoxy)butane

1-(5-chlorobenzoxazol-2-yl)-1-(3-(trifluoromethyl)phenoxy)butane

Conditions
ConditionsYield
With potassium carbonate In acetonitrile for 1h; Heating / reflux;100%
3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

propargyl bromide
106-96-7

propargyl bromide

1-(prop-2-yn-1-yloxy)-3-(trifluoromethyl)benzene
17061-88-0

1-(prop-2-yn-1-yloxy)-3-(trifluoromethyl)benzene

Conditions
ConditionsYield
With potassium carbonate In acetone; toluene for 24h; Williamson Ether Synthesis; Reflux;100%
With potassium carbonate In acetone for 24h; Inert atmosphere; Reflux;96.4%
With caesium carbonate In acetonitrile85%

3-Trifluoromethylphenol

3-Trifluoromethylphenol

N,N-Dimethylcarbamoyl chloride
79-44-7

N,N-Dimethylcarbamoyl chloride

3-(trifluoromethyl)phenyl dimethylcarbamate
722-08-7

3-(trifluoromethyl)phenyl dimethylcarbamate

Conditions
ConditionsYield
Stage #1: 3-Trifluoromethylphenol With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0℃; Inert atmosphere;
Stage #2: N,N-Dimethylcarbamoyl chloride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 3h; Inert atmosphere;
98%
With triethylamine
With triethylamine
3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

(R)-2,2-dimethyl-1,3-dioxolane-4-ylmethyl p-toluenesulfonate
23788-74-1

(R)-2,2-dimethyl-1,3-dioxolane-4-ylmethyl p-toluenesulfonate

(S)-(+)-2,2-dimethyl-4-(3-trifluoromethylphenoxy)methyl-1,3-dioxolane

(S)-(+)-2,2-dimethyl-4-(3-trifluoromethylphenoxy)methyl-1,3-dioxolane

Conditions
ConditionsYield
Stage #1: 3-Trifluoromethylphenol With sodium hydroxide In ethanol; water for 0.166667h;
Stage #2: (R)-2,2-dimethyl-1,3-dioxolane-4-ylmethyl p-toluenesulfonate In ethanol; water for 20h; Solvent; Reagent/catalyst; Temperature; Reflux;
98%
Stage #1: 3-Trifluoromethylphenol With sodium hydroxide In ethanol; water for 0.166667h;
Stage #2: (R)-2,2-dimethyl-1,3-dioxolane-4-ylmethyl p-toluenesulfonate In ethanol; water for 20h; Reflux;
89%
Stage #1: 3-Trifluoromethylphenol With sodium hydroxide In ethanol; water for 0.166667h;
Stage #2: (R)-2,2-dimethyl-1,3-dioxolane-4-ylmethyl p-toluenesulfonate In ethanol; water for 20h; Reflux;
88.7%
3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

sodium 2-bromo-2,2-difluoro-acetate

sodium 2-bromo-2,2-difluoro-acetate

α,α-difluoro(3-trifluoromethylphenoxy)acetic acid

α,α-difluoro(3-trifluoromethylphenoxy)acetic acid

Conditions
ConditionsYield
Stage #1: 3-Trifluoromethylphenol With sodium hydride In 1,4-dioxane at 20℃; for 0.5h; Inert atmosphere; Schlenk technique;
Stage #2: sodium 2-bromo-2,2-difluoro-acetate In 1,4-dioxane at 80℃; for 20h; Inert atmosphere;
98%
3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

3-(trifluoromethyl)phenyl methanesulfonate
52904-17-3

3-(trifluoromethyl)phenyl methanesulfonate

Conditions
ConditionsYield
With triethylamine In ethyl acetate at 0 - 20℃; for 0.166667h; Green chemistry;97%
With triethylamine In dichloromethane at 0℃; for 0.5h;92%
With pyridine
3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

chloroacetonitrile
107-14-2

chloroacetonitrile

(3-trifluoromethylphenoxy)acetonitrile
2145-31-5

(3-trifluoromethylphenoxy)acetonitrile

Conditions
ConditionsYield
With potassium carbonate In acetone Heating;97%
4-[(4-fluorophenyl)sulfonyl]tetrahydro-N-[(tetrahydro-2H-pyran-2-yl)oxy]-2H-pyran-4-carboxamide
226389-21-5

4-[(4-fluorophenyl)sulfonyl]tetrahydro-N-[(tetrahydro-2H-pyran-2-yl)oxy]-2H-pyran-4-carboxamide

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

C24H26F3NO7S
226399-23-1

C24H26F3NO7S

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl acetamide at 95℃; for 21h;97%
vinyl acetate
108-05-4

vinyl acetate

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

3-(trifluoromethyl)phenyl acetate
78950-34-2

3-(trifluoromethyl)phenyl acetate

Conditions
ConditionsYield
With 1,4-diaza-bicyclo[2.2.2]octane In neat (no solvent) at 70 - 140℃; for 0.183333h; Microwave irradiation;97%
3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

t-butyldimethylsilyl amine
41879-37-2

t-butyldimethylsilyl amine

tert-butyl-di-methyl(3-(trifluoromethyl)phenoxy)silane

tert-butyl-di-methyl(3-(trifluoromethyl)phenoxy)silane

Conditions
ConditionsYield
In neat (no solvent) at 20℃; for 0.5h; Green chemistry;97%
C13H13F3N4O5S

C13H13F3N4O5S

3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

C19H14F6N4O4

C19H14F6N4O4

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran at 20℃;96.8%
3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

(S)-(+)-(2,2-dimethyl-[1,3]dioxolan-4-yl)methanol
22323-82-6

(S)-(+)-(2,2-dimethyl-[1,3]dioxolan-4-yl)methanol

(S)-(+)-2,2-dimethyl-4-(3-trifluoromethylphenoxy)methyl-1,3-dioxolane

(S)-(+)-2,2-dimethyl-4-(3-trifluoromethylphenoxy)methyl-1,3-dioxolane

Conditions
ConditionsYield
With di-isopropyl azodicarboxylate; triphenylphosphine In toluene at 90 - 100℃; for 1.5h; Mitsunobu Displacement;96.46%
3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

1-Bromo-2-bromomethyl-benzene
3433-80-5

1-Bromo-2-bromomethyl-benzene

1-bromo-2-[3-(trifluoromethyl)phenoxymethyl]benzene
248582-57-2

1-bromo-2-[3-(trifluoromethyl)phenoxymethyl]benzene

Conditions
ConditionsYield
With potassium carbonate In acetone for 7h; Substitution; Heating;96%
3-Trifluoromethylphenol
98-17-9

3-Trifluoromethylphenol

ethyl 2-bromomethyl-2-propenoate
17435-72-2

ethyl 2-bromomethyl-2-propenoate

2-(3-trifluoromethyl-phenoxymethyl)-acrylic acid ethyl ester
1004992-01-1

2-(3-trifluoromethyl-phenoxymethyl)-acrylic acid ethyl ester

Conditions
ConditionsYield
Stage #1: 3-Trifluoromethylphenol; ethyl 2-bromomethyl-2-propenoate With potassium carbonate In acetone for 1.5h; Heating / reflux;
Stage #2: With triethylamine for 0.166667h;
96%
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