(Trifluoromethoxy)benzene supplier

Name
(Trifluoromethoxy)benzene
EINECS 207-269-5
CAS No. 456-55-3
Article Data49
CAS DataBase
Density 1.248 g/cm³
Solubility
Melting Point -50oC
Formula C₇H₅F₃O
Boiling Point 102.8 °C at 760 mmHg
Molecular Weight 162.111
Flash Point 12.2 °C
Transport Information UN 1993 3/PG 2
Appearance Colorless to light yellow liquid
Safety 16-26-36/37/39-9-33
Risk Codes 11-36/37/38
Molecular Structure
Hazard Symbols F, Xi, C
Synonyms Anisole, a,a,a-trifluoro- (6CI,7CI,8CI);Phenyltrifluoromethyl ether;Trifluoromethyl phenyl ether;a,a,a-Trifluoroanisole;
PSA 9.23000
LogP 2.58520

Synthetic route

: 34888-05-6
(trichloromethoxy)benzene

: 456-55-3
1-trifluoromethoxybenzene

Conditions

Conditions	Yield
With hydrogen fluoride at 95℃; under 21002.1 Torr; Temperature; Pressure; Autoclave;	95.46%
	90%
With antimonypentachloride; antimony(III) fluoride

: 24210-45-5
α,α-difluorophenoxyacetic acid

: 456-55-3
1-trifluoromethoxybenzene

Conditions

Conditions	Yield
With tetrafluoroboric acid; selectfluor II; silver nitrate In dichloromethane; water at 80℃; for 12h; Reagent/catalyst; Inert atmosphere;	84%
With xenon difluoride In chloroform-d1 at 23℃; for 0.0833333h; Inert atmosphere; Sealed tube;	39%
With phosphoric acid; silver trifluoromethanesulfonate; Selectfluor In dichloromethane; water at 55℃; for 1h; Catalytic behavior; Reagent/catalyst; Temperature; Solvent; Inert atmosphere; Glovebox;	90 %Spectr.

: 2-(trifluoromethoxy)biphenylyl-2'-diazonium hexafluoroantimonate

: 108-95-2
phenol

A: 132-64-9
dibenzofuran

B: 456-55-3
1-trifluoromethoxybenzene

Conditions

Conditions	Yield
at 42℃; for 3h;	A 78% B n/a

...Expand

: 2-(trifluoromethoxy)biphenylyl-2'-diazonium tetrafluoroborate

: 108-95-2
phenol

A: 132-64-9
dibenzofuran

B: 456-55-3
1-trifluoromethoxybenzene

Conditions

Conditions	Yield
at 42℃; for 3h;	A 76% B n/a

...Expand

: 461-81-4
1-chloro-4-(trifluoromethoxy)benzene

: 456-55-3
1-trifluoromethoxybenzene

Conditions

Conditions	Yield
With sodium hydroxide; hydrogen; palladium on activated charcoal In ethanol under 2068.6 Torr; for 5h;	74.4%

: 2-(trifluoromethoxy)biphenylyl-2'-diazonium hexafluorophosphate

: 108-95-2
phenol

A: 132-64-9
dibenzofuran

B: 456-55-3
1-trifluoromethoxybenzene

Conditions

Conditions	Yield
at 42℃; for 3h;	A 74% B n/a

...Expand

: 2-(trifluoromethoxy)biphenylyl-2'-diazonium triflate

: 108-95-2
phenol

A: 132-64-9
dibenzofuran

B: 456-55-3
1-trifluoromethoxybenzene

Conditions

Conditions	Yield
at 42℃; for 3h;	A 74% B n/a

...Expand

: 56-23-5
tetrachloromethane

: 108-95-2
phenol

A: 456-55-3
1-trifluoromethoxybenzene

B: 603-45-2
aurin

Conditions

Conditions	Yield
With hydrogen fluoride	A 31% B 69%

...Expand

: 63465-11-2
Bis-(trifluormethyl)-bis-(trifluormethoxy)-sulfuran

: 108-95-2
phenol

: 456-55-3
1-trifluoromethoxybenzene

Conditions

Conditions	Yield
In diethyl ether 25°C, 0.5 h;	53%

: 129922-37-8
S-(trifluoromethyl)-3,7-dinitrodibenzothiophenium trifluoromethanesulfonate

: 108-95-2
phenol

: 456-55-3
1-trifluoromethoxybenzene

Conditions

Conditions	Yield
at 80℃; for 1.5h;	13%

: 770-11-6
difluorochloromethoxybenzene

: 456-55-3
1-trifluoromethoxybenzene

Conditions

Conditions	Yield
With antimonypentachloride; antimony(III) fluoride

: 461-82-5
4-(trifluoromethoxy)aniline

: 456-55-3
1-trifluoromethoxybenzene

Conditions

Conditions	Yield
With hypophosphoric acid Diazotization;

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 71-43-2
benzene

A: 462-06-6
fluorobenzene

B: 540-36-3
para-difluorobenzene

C: 456-55-3
1-trifluoromethoxybenzene

Conditions

Conditions	Yield
In dichloromethane at 0℃; Title compound not separated from byproducts;	A 39 % Chromat. B 2 % Chromat. C 2 % Chromat.

...Expand

: 71-43-2
benzene

A: 462-06-6
fluorobenzene

B: 540-36-3
para-difluorobenzene

C: 456-55-3
1-trifluoromethoxybenzene

Conditions

Conditions	Yield
With hypofluorous acid trifluoromethyl ester In dichloromethane at 0℃; Product distribution; other sub. aromatic hydrocarbons and anilines; other solvents and temp.;
With hypofluorous acid trifluoromethyl ester In dichloromethane at 0℃; Title compound not separated from byproducts;	A 39 % Chromat. B 2 % Chromat. C 2 % Chromat.

...Expand

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 71-43-2
benzene

nitrogen: nitrogen

A: 462-06-6
fluorobenzene

B: 456-55-3
1-trifluoromethoxybenzene

...Expand

: 34888-05-6
(trichloromethoxy)benzene

A: 456-55-3
1-trifluoromethoxybenzene

B: 770-11-6
difluorochloromethoxybenzene

Conditions

Conditions	Yield
With hydrogen fluoride; antimonypentachloride at 50℃; under 7500.6 Torr; for 1h; Product distribution; Further Variations:; Reagents; Temperatures; time;
With hydrogen fluoride; antimonypentachloride at 50℃; under 7500.75 Torr; for 1h; Inert atmosphere; Autoclave;

: 5-tert-butyl-2'-(trifluoromethoxy)biphenylyl-2-diazonium hexafluoroantimonate

: 108-95-2
phenol

: 456-55-3
1-trifluoromethoxybenzene

Conditions

Conditions	Yield
Stage #1: 5-tert-butyl-2'-(trifluoromethoxy)biphenylyl-2-diazonium hexafluoroantimonate In dichloromethane at -100 - -90℃; for 1.16667h; Irradiation; Stage #2: phenol With N-ethyl-N,N-diisopropylamine In dichloromethane at -90 - -10℃; for 3h; Further stages.;

: 106-48-9
4-chloro-phenol

KOH-solution: KOH-solution

: 456-55-3
1-trifluoromethoxybenzene

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 60.7 percent / HF / 150 °C / several hours 2: 74.4 percent / H2, NaOH / 10percent Pd/C / ethanol / 5 h / 2068.6 Torr View Scheme

: 98273-25-7
dichloro-phenoxy-methanesulfenyl chloride

: 456-55-3
1-trifluoromethoxybenzene

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: chlorine 2: antimony (III)-fluoride; antimony (V)-chloride View Scheme
Multi-step reaction with 3 steps 1: chlorine 2: antimony (III)-fluoride 3: antimony (III)-fluoride; antimony (V)-chloride View Scheme

: 1005-56-7
phenylcarbonochloridothioate

: 456-55-3
1-trifluoromethoxybenzene

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: chlorine 2: chlorine 3: antimony (III)-fluoride; antimony (V)-chloride View Scheme
Multi-step reaction with 4 steps 1: chlorine 2: chlorine 3: antimony (III)-fluoride 4: antimony (III)-fluoride; antimony (V)-chloride View Scheme

: 451-85-4
1,3-dichloro-4-(trifluoromethoxy)benzene

: 456-55-3
1-trifluoromethoxybenzene

: 1006904-71-7
2-(dimethylamino)-1,3-dimethylimidazolidin-2-ylium trifluoromethanolate

: 88284-48-4
2-(trimethylsilyl)phenyl trifluoromethanesulfonate

A: 462-06-6
fluorobenzene

B: 456-55-3
1-trifluoromethoxybenzene

Conditions

Conditions	Yield
In diethyl ether; acetonitrile at 0 - 20℃; Title compound not separated from byproducts.;

...Expand

: 456-56-4
phenyl trifluoromethylsulfide

A: 426-58-4
(trifluoromethylsulfonyl)benzene

B: 456-55-3
1-trifluoromethoxybenzene

: 66632-46-0
bis(trifluoromethyl)bis(trifluoromethoxy)oxosulfur(VI)

: 108-95-2
phenol

A: 456-55-3
1-trifluoromethoxybenzene

B: 72971-96-1
bis(trifluoromethyl)sulfone

Conditions

Conditions	Yield
In diethyl ether 25°C, 0.5 h;

...Expand

: 106-39-8
bromochlorobenzene

: 407-14-7
1-bromo-4-(trifluoromethoxy)benzene

A: 456-55-3
1-trifluoromethoxybenzene

B: 108-90-7
chlorobenzene

Conditions

Conditions	Yield
Stage #1: bromochlorobenzene; 1-bromo-4-(trifluoromethoxy)benzene With TurboGrignard In tetrahydrofuran at 0℃; Stage #2: With methanol In tetrahydrofuran Reactivity;

...Expand

: 108-37-2
1-bromo-3-chlorobenzene

: 2252-44-0
1-bromo-3-(trifluoromethoxy)benzene

A: 456-55-3
1-trifluoromethoxybenzene

B: 108-90-7
chlorobenzene

Conditions

Conditions	Yield
Stage #1: 1-bromo-3-chlorobenzene; 1-bromo-3-(trifluoromethoxy)benzene With TurboGrignard In tetrahydrofuran at 0℃; Stage #2: With methanol In tetrahydrofuran Reactivity;

...Expand

: 108-37-2
1-bromo-3-chlorobenzene

: 407-14-7
1-bromo-4-(trifluoromethoxy)benzene

A: 456-55-3
1-trifluoromethoxybenzene

B: 108-90-7
chlorobenzene

Conditions

Conditions	Yield
Stage #1: 1-bromo-3-chlorobenzene; 1-bromo-4-(trifluoromethoxy)benzene With TurboGrignard In tetrahydrofuran at 0℃; Stage #2: With methanol In tetrahydrofuran Reactivity;

...Expand

: 694-80-4
2-bromo-1-chlorobenzene

: 64115-88-4
1-bromo-2-(trifluoromethoxy)benzene

A: 456-55-3
1-trifluoromethoxybenzene

B: 108-90-7
chlorobenzene

Conditions

Conditions	Yield
Stage #1: 2-bromo-1-chlorobenzene; 1-bromo-2-(trifluoromethoxy)benzene With TurboGrignard In tetrahydrofuran at 0℃; Stage #2: With methanol In tetrahydrofuran Reactivity;

...Expand

: 2252-44-0
1-bromo-3-(trifluoromethoxy)benzene

: 623-00-7
4-bromobenzenecarbonitrile

A: 456-55-3
1-trifluoromethoxybenzene

B: 100-47-0
benzonitrile

Conditions

Conditions	Yield
Stage #1: 1-bromo-3-(trifluoromethoxy)benzene; 4-bromobenzenecarbonitrile With TurboGrignard In tetrahydrofuran at 0℃; Stage #2: With methanol In tetrahydrofuran Reactivity;

...Expand

: 456-55-3
1-trifluoromethoxybenzene

: 175278-00-9
1-iodo-2-(trifluoromethoxy)benzene

Conditions

Conditions	Yield
Stage #1: 1-trifluoromethoxybenzene With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium In tetrahydrofuran Stage #2: With iodine In tetrahydrofuran	99%

: 456-55-3
1-trifluoromethoxybenzene

A: 34888-05-6
(trichloromethoxy)benzene

B: 1544-69-0
α,α,α-dichlorofluoromethoxybenzene

Conditions

Conditions	Yield
With aluminium trichloride In dichloromethane at 0 - 10℃; for 0.5h;	A 98.2% B 1.8%

: 456-55-3
1-trifluoromethoxybenzene

: 461-82-5
4-(trifluoromethoxy)aniline

Conditions

Conditions	Yield
Stage #1: 1-trifluoromethoxybenzene With sodium ferrate(VI); sodium bromide In dimethyl sulfoxide at 95℃; for 4h; Inert atmosphere; Stage #2: With sodium amide In dimethyl sulfoxide at 155℃; under 3040.2 Torr; for 10h; Solvent; Temperature; Reagent/catalyst; Pressure; Inert atmosphere;	98.2%
Multi-step reaction with 2 steps 1: sulfuric acid; nitric acid / dichloromethane / 2 h / 0 - 30 °C 2: iron; hydrogenchloride / methanol / 2 h / 60 - 65 °C View Scheme

: 456-55-3
1-trifluoromethoxybenzene

: 98-59-9
p-toluenesulfonyl chloride

: 87750-49-0
trifluoromethoxy-4 phenyl, methyl-4' phenyl sulfone

Conditions

Conditions	Yield
With hydrogen fluoride; boron trifluoride at 20℃; for 23h;	94%
With potassium hydroxide; HF In water	94%

: 456-55-3
1-trifluoromethoxybenzene

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: 94651-33-9
2-(trifluoromethoxy)benzaldehyde

Conditions

Conditions	Yield
Stage #1: 1-trifluoromethoxybenzene With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium In tetrahydrofuran; cyclohexane at -75℃; for 2h; Stage #2: N,N-dimethyl-formamide In tetrahydrofuran; cyclohexane at -75℃; Further stages.;	93%

: 456-55-3
1-trifluoromethoxybenzene

: 403-43-0
4-fluorobenzoyl chloride

: 87996-56-3
trifluoromethoxy-4 fluoro-4' benzophenone

Conditions

Conditions	Yield
With hydrogen fluoride; boron trifluoride at 20℃; for 2h;	92%

: 456-55-3
1-trifluoromethoxybenzene

: 122-01-0
4-chloro-benzoyl chloride

: 87996-55-2
(4-chlorophenyl)(4-(trifluoromethoxy)phenyl)methanone

Conditions

Conditions	Yield
With hydrogen fluoride; boron trifluoride at 10℃; for 3h;	92%

: 456-55-3
1-trifluoromethoxybenzene

: 75-36-5
acetyl chloride

: 85013-98-5
1-[4-(trifluoromethoxy)phenyl]ethan-1-one

Conditions

Conditions	Yield
With hydrogen fluoride; boron trifluoride at 20℃; for 3h; further acid chlorides;	91%
With hydrogen fluoride; boron trifluoride at 20℃; for 3h;	91%
With iron(III) chloride In nitromethane for 1h; Product distribution; Ambient temperature; investigation of the acetylation reaction; relative reactivity data compared to benzene;	100 % Chromat.

: 456-55-3
1-trifluoromethoxybenzene

: 312-94-7
2-trifluoromethylbenzoyl chloride

: 87996-57-4
trifluoromethoxy-4 trifluoromethyl-2' benzophenone

Conditions

Conditions	Yield
With hydrogen fluoride; boron trifluoride at 30℃; for 2h;	91%

: 456-55-3
1-trifluoromethoxybenzene

: 329-15-7
4-trifluoromethyl-phenyl acetyl chloride

: 34367-37-8
trifluoromethoxy-4 trifluoromethyl-4' benzophenone

Conditions

Conditions	Yield
With hydrogen fluoride; boron trifluoride at 30℃; for 4h;	90%

: 456-55-3
1-trifluoromethoxybenzene

: 79-30-1
isobutyryl chloride

: 56425-84-4
2-methyl-1-(4-(trifluoromethoxy)phenyl)propan-1-one

Conditions

Conditions	Yield
With hydrogen fluoride; boron trifluoride at 0℃; for 5h;	90%

: 456-55-3
1-trifluoromethoxybenzene

: 609-65-4
o-chlorobenzoyl chloride

: 87996-54-1
trifluoromethoxy-4 chloro-2' benzophenone

Conditions

Conditions	Yield
With hydrogen fluoride; boron trifluoride at 20℃; for 1h;	89%

: 456-55-3
1-trifluoromethoxybenzene

: 175676-65-0
2-trifluoromethoxyphenylboronic acid

Conditions

Conditions	Yield
Stage #1: 1-trifluoromethoxybenzene With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium In tetrahydrofuran; cyclohexane at -75℃; for 2h; Stage #2: With fluorodimethoxyborane diethyl etherate In tetrahydrofuran; cyclohexane at -75℃; Stage #3: With water In tetrahydrofuran; cyclohexane for 0.5h; Further stages.;	89%

: 456-55-3
1-trifluoromethoxybenzene

: 32858-93-8
2-(trifluoromethoxy)phenol

Conditions

Conditions	Yield
Stage #1: 1-trifluoromethoxybenzene With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium In tetrahydrofuran; cyclohexane at -75℃; for 2h; Stage #2: With fluorodimethoxyborane diethyl etherate In tetrahydrofuran; cyclohexane at -75℃; Stage #3: With sodium hydroxide; dihydrogen peroxide In tetrahydrofuran; cyclohexane Further stages.;	88%

: 456-55-3
1-trifluoromethoxybenzene

: 4755-77-5
Ethyl oxalyl chloride

: ethyl 2-oxo-2-[2-(trifluoromethoxy)phenyl]acetate

Conditions

Conditions	Yield
Stage #1: 1-trifluoromethoxybenzene With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium In tetrahydrofuran; cyclohexane at -75℃; for 2h; Stage #2: Ethyl oxalyl chloride In tetrahydrofuran; cyclohexane at -75℃; Further stages.;	87%

: 456-55-3
1-trifluoromethoxybenzene

: 148992-43-2
1-ethoxy-2,2-difluoroethanol

: 1314534-88-7
1,1-difluoro-2,2-bis[p-(trifluoromethoxy)benzene]ethane

Conditions

Conditions	Yield
With boron trifluoride monohydrate In water at 0℃; for 1h; Friedel Crafts hydroxyalkylation;	86%

: 456-55-3
1-trifluoromethoxybenzene

: 713-65-5
4-nitrophenyl trifluoromethyl ether

Conditions

Conditions	Yield
With sulfuric acid; nitric acid In dichloromethane at 0 - 30℃; for 2h;	85%

: 456-55-3
1-trifluoromethoxybenzene

: 407-14-7
1-bromo-4-(trifluoromethoxy)benzene

Conditions

Conditions	Yield
With bromine; iron at 100℃; for 16h;	83.8%

: 456-55-3
1-trifluoromethoxybenzene

: 7353-91-5
4-dimethylaminophenylmagnesium bromide

: 1137-79-7
N,N-dimethyl-4-biphenylamine

Conditions

Conditions	Yield
With C68H72Cl2N6NiP2 In toluene at 120℃; for 16h; Inert atmosphere;	83%

: 456-55-3
1-trifluoromethoxybenzene

: 2926-29-6
Langlois reagent

: 1-trifluoromethanesulfinyl-4-trifluoromethoxy-benzene

Conditions

Conditions	Yield
With trifluoromethylsulfonic anhydride at 20℃;	82%

: 456-55-3
1-trifluoromethoxybenzene

: 618-46-2
m-Chlorobenzoyl chloride

: 1146289-22-6
(3-chlorophenyl)(2-trifluoromethoxyphenyl)methanone

Conditions

Conditions	Yield
Stage #1: 1-trifluoromethoxybenzene With aluminum tris-(tert-butyl-(1-isopropyl-2,2-dimethyl-propyl)amide)-tris(lithium chloride) In tetrahydrofuran at 0℃; for 3h; Inert atmosphere; Stage #2: With zinc(II) chloride In tetrahydrofuran at -30℃; for 0.25h; Inert atmosphere; Stage #3: m-Chlorobenzoyl chloride With copper(I) cyanide*2 lithium chloride In tetrahydrofuran at -30 - 25℃; Inert atmosphere; regioselective reaction;	81%

Yield

Stage #1: 1-trifluoromethoxybenzene With aluminum tris-(tert-butyl-(1-isopropyl-2,2-dimethyl-propyl)amide)-tris(lithium chloride) In tetrahydrofuran at 0℃; for 3h; Inert atmosphere;
Stage #2: With zinc(II) chloride In tetrahydrofuran at -30℃; for 0.25h; Inert atmosphere;
Stage #3: m-Chlorobenzoyl chloride With copper(I) cyanide*2 lithium chloride In tetrahydrofuran at -30 - 25℃; Inert atmosphere; regioselective reaction;

81%

: 456-55-3
1-trifluoromethoxybenzene

: 75-36-5
acetyl chloride

A: 34888-05-6
(trichloromethoxy)benzene

B: 85013-98-5
1-[4-(trifluoromethoxy)phenyl]ethan-1-one

Conditions

Conditions	Yield
With aluminium trichloride In tetrachloromethane for 2h; Product distribution; Further Variations:; Solvents;	A 80% B 20%

...Expand

: 1942-46-7
5-decyne

: 456-55-3
1-trifluoromethoxybenzene

: 1613114-49-0
1,2,3,4-tetrabutyl-6-(trifluoromethoxy)naphthalene

Conditions

Conditions	Yield
With copper(II) 2-ethylhexanoate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; 2,2',3,3',4,4',5,5',6,6'-Decabromodiphenyl ether at 160℃; for 3h; Inert atmosphere; Microwave irradiation;	80%

: 617-86-7
triethylsilane

: 456-55-3
1-trifluoromethoxybenzene

A: 358-43-0
triethylsilyl fluoride

B: 100-66-3
methoxybenzene

Conditions

Conditions	Yield
With C21H16N3P(2+) In dichloromethane at 50℃; for 96h; Reagent/catalyst;	A 80% B n/a

...Expand

: 456-55-3
1-trifluoromethoxybenzene

A: 713-65-5
4-nitrophenyl trifluoromethyl ether

B: 1644-88-8
o-nitro-α,α,α-trifluoromethoxybenzene

Conditions

Conditions	Yield
With magnesium(II) perchlorate; N–nitrosaccharin In [D3]acetonitrile at 85℃; for 19h; Inert atmosphere; Sealed tube; Overall yield = 97 percent;	A 79.7% B 17.3%
With nitronium tetrafluoborate In nitromethane at 25℃; for 2h; Product distribution; further nitrating reagents, solvents and temperature; investigation of the nitration reaction; Hammett-Brown plot (relative reactivity data compared to benzene);	A 88.5 % Chromat. B 11.5 % Chromat.
With sulfuric acid; nitric acid at -0.16℃; Temperature; Flow reactor;	A 90.97 %Chromat. B 7.26 %Chromat.

: 124-38-9
carbon dioxide

: 456-55-3
1-trifluoromethoxybenzene

: 1979-29-9
2-(trifluoromethoxy)benzoic acid

Conditions

Conditions	Yield
Stage #1: 1-trifluoromethoxybenzene With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium In tetrahydrofuran; cyclohexane at -75℃; for 2h; Stage #2: carbon dioxide In tetrahydrofuran; cyclohexane at -78℃; Further stages.;	78%

(Trifluoromethoxy)benzene Chemical Properties

Product Name: (Trifluoromethoxy)benzene (CAS NO.456-55-3)

Molecular Formula: C₇H₅F₃O
Molecular Weight: 162.11g/mol
Mol File: 456-55-3.mol
EINECS: 207-269-5
Appearance: Colorless to light yellow liquid
Boiling point: 102.8 °C at 760 mmHg
Storage Temperature: Flammables area
Flash Point: 12.2 °C
Density: 1.248 g/cm³
Refractive index: n20/D 1.406(lit.)
Index of Refraction: 1.427
Molar Refractivity: 33.38 cm³
Molar Volume: 129.8 cm³
Surface Tension: 24 dyne/cm
Enthalpy of Vaporization: 32.78 kJ/mol
Vapour Pressure: 38.3 mmHg at 25°C
XLogP3-AA: 3.2
H-Bond Donor: 0
H-Bond Acceptor: 4
Structure Descriptors of (Trifluoromethoxy)benzene (CAS NO.456-55-3):
IUPAC Name: trifluoromethoxybenzene
Canonical SMILES: C1=CC=C(C=C1)OC(F)(F)F
InChI: InChI=1S/C7H5F3O/c8-7(9,10)11-6-4-2-1-3-5-6/h1-5H
InChIKey: GQHWSLKNULCZGI-UHFFFAOYSA-N
Product Categories: Trifluoromethoxybenzene Series; Aromatic Halides (substituted)

(Trifluoromethoxy)benzene Safety Profile

Safety Information of (Trifluoromethoxy)benzene (CAS NO.456-55-3):
Hazard Codes: F,Xi Irritant ,C Corrosive
Risk Statements: 11-36/37/38
R11:Highly flammable.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 16-26-36/37/39-9-33
S16:Keep away from sources of ignition.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S9:Keep container in a well-ventilated place.
S33:Take precautionary measures against static discharges.
RIDADR: UN 1993 3/PG 2
WGK Germany: 3
Hazard Note: Flammable/Corrosive
TSCA: T
HazardClass: 3
PackingGroup: II

(Trifluoromethoxy)benzene Specification

(Trifluoromethoxy)benzene , its CAS NO. is 456-55-3, the synonym is Benzene, (trifluoromethoxy)- .

Product Name

(Trifluoromethoxy)benzene

Synthetic route

(Trifluoromethoxy)benzene Chemical Properties

(Trifluoromethoxy)benzene Safety Profile

(Trifluoromethoxy)benzene Specification

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