Product Name

  • Name

    1,3-Dibromopropane

  • EINECS 203-690-3
  • CAS No. 109-64-8
  • Article Data68
  • CAS DataBase
  • Density 1.933 g/cm3
  • Solubility 1.7 g/L (30 °C) in water
  • Melting Point -34 °C(lit.)
  • Formula C3H6Br2
  • Boiling Point 167 °C at 760 mmHg
  • Molecular Weight 201.889
  • Flash Point 54.4 °C
  • Transport Information UN 1993 3/PG 3
  • Appearance colourless to slightly yellow liquid
  • Safety 16-26-36-61-24/25
  • Risk Codes 10-22-38-51/53-36/37/38
  • Molecular Structure Molecular Structure of 109-64-8 (1,3-Dibromopropane)
  • Hazard Symbols IrritantXi
  • Synonyms .omega.,.omega.-Dibromopropane;Trimethylene dibromide;propane, 1,3-dibromo-;1/C3H6Br2/c4-2-1-3-5/h1-3H;1,3-Dibromopropane/109-64-8;1,3-Dibromopropane / Trimethylene Dibromide;Trimethylene bromide;
  • PSA 0.00000
  • LogP 2.16630

Synthetic route

3-ethoxy-1-propanol
111-35-3

3-ethoxy-1-propanol

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Conditions
ConditionsYield
With sulfuric acid; hydrogen bromide for 10h; Heating;91%
1,3-bis(trimethylsiloxy)propane
17887-80-8

1,3-bis(trimethylsiloxy)propane

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Conditions
ConditionsYield
With Tri-n-butylfluorphosphoniumbromid In benzene at 20℃; for 24h;76%
trimethylene oxide
503-30-0

trimethylene oxide

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Conditions
ConditionsYield
With hydrogen bromide at 100℃;
1,2-Dibromopropane
78-75-1

1,2-Dibromopropane

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Conditions
ConditionsYield
at 240 - 250℃; beim Erhitzen im Rohr;
1,2-Dibromopropane
78-75-1

1,2-Dibromopropane

A

2,2-dibromopropane
594-16-1

2,2-dibromopropane

B

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Conditions
ConditionsYield
beim Erhitzen;
propane
74-98-6

propane

A

1,2-Dibromopropane
78-75-1

1,2-Dibromopropane

B

propyl bromide
106-94-5

propyl bromide

C

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

D

isopropyl bromide
75-26-3

isopropyl bromide

Conditions
ConditionsYield
at 300 - 330℃; Bromierung; weitere Produkte: 2.2-Dibrom-propan, Tribrompropan und Tetrabrompropan;
1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

A

1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

B

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Conditions
ConditionsYield
With ethyl bromide; aluminum tri-bromide at 2 - 5℃;
ethanol
64-17-5

ethanol

1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

A

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

B

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Conditions
ConditionsYield
With aluminium trichloride; hydrogen bromide
diacetyl peroxide
110-22-5

diacetyl peroxide

allyl bromide
106-95-6

allyl bromide

A

1-butylene
106-98-9

1-butylene

B

methyl bromide
74-83-9

methyl bromide

C

5-bromo-4-(bromomethyl)pent-1-ene
157556-86-0

5-bromo-4-(bromomethyl)pent-1-ene

D

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Conditions
ConditionsYield
at 90℃; entstehen noch 1.5-Dibrom-2-brommethyl-pentan(?) und CO2;
allyl bromide
106-95-6

allyl bromide

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Conditions
ConditionsYield
With hydrogen bromide at -78℃; Irradiation.im UV-Licht; bei Sauerstoffausschluss;
With hydrogen bromide; oxygen
With hydrogen bromide; dibenzoyl peroxide
allyl bromide
106-95-6

allyl bromide

A

1,2-Dibromopropane
78-75-1

1,2-Dibromopropane

B

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Conditions
ConditionsYield
With hydrogen bromide at 100℃;
ethene
74-85-1

ethene

1,2-dibromomethane
74-95-3

1,2-dibromomethane

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Conditions
ConditionsYield
With water; dibenzoyl peroxide at 100℃; under 228007 - 257428 Torr;
trimethyleneglycol
504-63-2

trimethyleneglycol

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Conditions
ConditionsYield
With hydrogen bromide at 100℃;
With triphenyl phosphite; bromine
With hydrogen bromide
1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Conditions
ConditionsYield
With Aliquat 336; lithium bromide at 98℃; for 6h;92 % Chromat.
1,3-chlorobromopropane
109-70-6

1,3-chlorobromopropane

A

1,2-Dichloropropane
26198-63-0, 78-87-5

1,2-Dichloropropane

B

1,2-Dibromopropane
78-75-1

1,2-Dibromopropane

C

1,3-Dichloropropane
142-28-9

1,3-Dichloropropane

D

allyl bromide
106-95-6

allyl bromide

E

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

F

3-chloroprop-1-ene
107-05-1

3-chloroprop-1-ene

Conditions
ConditionsYield
aluminum oxide at 160℃; Mechanism; Product distribution; different temperature;
trimethylene oxide
503-30-0

trimethylene oxide

hydrogen bromide
10035-10-6, 12258-64-9

hydrogen bromide

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

hydrogen bromide
10035-10-6, 12258-64-9

hydrogen bromide

3-phenoxypropyl bromide
588-63-6

3-phenoxypropyl bromide

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

bromine
7726-95-6

bromine

cyclopropane
75-19-4

cyclopropane

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Conditions
ConditionsYield
im Sonnenlicht;
ethanol
64-17-5

ethanol

bromine
7726-95-6

bromine

cyclopropane
75-19-4

cyclopropane

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Conditions
ConditionsYield
at 20℃; Irradiation;
hydrogen bromide
10035-10-6, 12258-64-9

hydrogen bromide

allyl bromide
106-95-6

allyl bromide

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Conditions
ConditionsYield
at -78℃; bei Einw. von UV-Licht;
at 25℃; bei Einw. von UV-Licht;
bromine
7726-95-6

bromine

cyclopropane
75-19-4

cyclopropane

isopentyl nitrite
110-46-3

isopentyl nitrite

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Conditions
ConditionsYield
at 20℃; Irradiation;
bromopropyl-phenyl ether

bromopropyl-phenyl ether

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Conditions
ConditionsYield
With hydrogen bromide beim Erhitzen im Rohr;
hydrogen bromide
10035-10-6, 12258-64-9

hydrogen bromide

allyl bromide
106-95-6

allyl bromide

cobalt

cobalt

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

hydrogen bromide
10035-10-6, 12258-64-9

hydrogen bromide

allyl bromide
106-95-6

allyl bromide

iron

iron

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

hydrogen bromide
10035-10-6, 12258-64-9

hydrogen bromide

allyl bromide
106-95-6

allyl bromide

nickel

nickel

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

bromine
7726-95-6

bromine

cyclopropane
75-19-4

cyclopropane

oxygen

oxygen

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Conditions
ConditionsYield
at 20℃; Irradiation;
hydrogen bromide
10035-10-6, 12258-64-9

hydrogen bromide

allyl bromide
106-95-6

allyl bromide

oxygen

oxygen

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

hydrogen bromide
10035-10-6, 12258-64-9

hydrogen bromide

allyl bromide
106-95-6

allyl bromide

peroxidene

peroxidene

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1-Methylpyrrolidine
120-94-5

1-Methylpyrrolidine

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1-(3-bromopropyl)-1-methylpyrrolidin-1-ium bromide
3722-27-8

1-(3-bromopropyl)-1-methylpyrrolidin-1-ium bromide

Conditions
ConditionsYield
Reflux;100%
at 20℃; for 48h; Darkness;92%
With benzene
In acetone at 20℃; for 168h; Darkness;
triphenylphosphine
603-35-0

triphenylphosphine

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

3-bromopropyltriphenylphosphonium bromide
3607-17-8

3-bromopropyltriphenylphosphonium bromide

Conditions
ConditionsYield
In toluene at 110℃; for 16h;100%
In toluene for 24h; Reflux;99%
In toluene Inert atmosphere; Reflux;98%
ethyl N-hydroxylcarbamate
589-41-3

ethyl N-hydroxylcarbamate

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

N-(ethoxycarbonyl)isoxazolidine
54020-55-2

N-(ethoxycarbonyl)isoxazolidine

Conditions
ConditionsYield
With sodium t-butanolate In tert-butyl alcohol at 65℃; for 6h; cyclocondensation;100%
With potassium hydroxide In ethanol for 2h; Heating;85%
With potassium hydroxide
1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1,3-diazido-propane
100910-72-3

1,3-diazido-propane

Conditions
ConditionsYield
With sodium azide In dimethyl sulfoxide at 20℃;100%
With sodium azide In water; N,N-dimethyl-formamide at 80℃; for 20h;97%
With sodium azide In dimethyl sulfoxide at 20℃; for 24h; Inert atmosphere;90%
1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

Diethyl methylmalonate
609-08-5

Diethyl methylmalonate

heptane-2,2,6,6-tetracarboxylic acid tetraethyl ester
33524-34-4

heptane-2,2,6,6-tetracarboxylic acid tetraethyl ester

Conditions
ConditionsYield
With sodium ethanolate In ethanol at 24℃; Substitution; Heating;100%
(i) NaH, benzene, (ii) /BRN= 635662/; Multistep reaction;
[2,2]bipyridinyl
366-18-7

[2,2]bipyridinyl

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

6H-7,8-dihydropyrido<1,2-a:2,1-c><1,4>diazepine-5,9-diium dibromide
2895-98-9

6H-7,8-dihydropyrido<1,2-a:2,1-c><1,4>diazepine-5,9-diium dibromide

Conditions
ConditionsYield
In acetone Heating;100%
for 12h; Reflux;90%
In acetonitrile
7-hydroxy-2H-chromen-2-one
93-35-6

7-hydroxy-2H-chromen-2-one

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

7-(3-bromopropoxy)−2H-chromen-2-one
69150-28-3

7-(3-bromopropoxy)−2H-chromen-2-one

Conditions
ConditionsYield
With potassium carbonate In acetone for 12h; Reflux;100%
With potassium carbonate In acetonitrile Reflux;86.9%
With potassium carbonate In acetone Reflux;79%
2,3:7,6-bis(2',3'-quinolino)tetracyclo<6.3.0.04,11.05,9>undecane
113258-55-2

2,3:7,6-bis(2',3'-quinolino)tetracyclo<6.3.0.04,11.05,9>undecane

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1',1''-trimethylene-2,3:7,6-bis(2,',3'-quinolino)tetracyclo<6.3.0.04,11.05,9>undecane dibromide
131251-79-1

1',1''-trimethylene-2,3:7,6-bis(2,',3'-quinolino)tetracyclo<6.3.0.04,11.05,9>undecane dibromide

Conditions
ConditionsYield
at 120℃; for 36h;100%
1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

4-methyl-4'-<2-(1H-pyrrol-1-yl)ethyl>-2,2'-bipyridine
104119-85-9

4-methyl-4'-<2-(1H-pyrrol-1-yl)ethyl>-2,2'-bipyridine

4-methyl-4'-<2-(1H-pyrrol-1-yl)ethyl>-N,N'-(trimethylene)-2,2'-bipyridinium dibromide

4-methyl-4'-<2-(1H-pyrrol-1-yl)ethyl>-N,N'-(trimethylene)-2,2'-bipyridinium dibromide

Conditions
ConditionsYield
at 100℃; for 24h;100%
p-Chlorothiophenol
106-54-7

p-Chlorothiophenol

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

(3-bromopropyl)(4-chlorophenyl)sulfane
27983-06-8

(3-bromopropyl)(4-chlorophenyl)sulfane

Conditions
ConditionsYield
With potassium carbonate In acetone at 80℃; for 48h;100%
With potassium carbonate; potassium iodide In acetone at 20℃;56.3%
With potassium carbonate In acetonitrile at 70℃; for 16h;40%
benzoimidazole
51-17-2

benzoimidazole

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1,3-bis(N-benzimidazolyl)propane
39677-02-6

1,3-bis(N-benzimidazolyl)propane

Conditions
ConditionsYield
Stage #1: benzoimidazole With sodium hydride In tetrahydrofuran; mineral oil at 0 - 20℃; for 2h; Inert atmosphere;
Stage #2: 1,3-dibromo-propane In tetrahydrofuran; mineral oil for 6h; Reflux; Inert atmosphere;
100%
Stage #1: benzoimidazole With sodium hydride In tetrahydrofuran at 0℃;
Stage #2: 1,3-dibromo-propane In tetrahydrofuran
85%
81%
1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

C39H50O5Si
206259-62-3

C39H50O5Si

[2-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxy)-1-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxymethyl)-ethoxy]-tert-butyl-dimethyl-silane
206259-63-4

[2-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxy)-1-(4-{1-[4-(3-bromo-propoxy)-phenyl]-1-methyl-ethyl}-phenoxymethyl)-ethoxy]-tert-butyl-dimethyl-silane

Conditions
ConditionsYield
With potassium carbonate In acetone Etherification;100%
carbon disulfide
75-15-0

carbon disulfide

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

acetylacetone
123-54-6

acetylacetone

3‐(1,3-dithiane-2-yl)pentane-2,4-dione
55727-23-6

3‐(1,3-dithiane-2-yl)pentane-2,4-dione

Conditions
ConditionsYield
With potassium carbonate100%
Stage #1: carbon disulfide; acetylacetone With tetrabutylammomium bromide; potassium carbonate In water at 20℃;
Stage #2: 1,3-dibromo-propane In water at 20℃; for 8h;
92%
With potassium carbonate In N,N-dimethyl-formamide for 7h;74%
2-mercaptoethylamine hydrochloride
156-57-0

2-mercaptoethylamine hydrochloride

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

3,7-dithianonane-1,9-diamine
57383-24-1

3,7-dithianonane-1,9-diamine

Conditions
ConditionsYield
With sodium methylate In methanol at 40℃; for 10h; Inert atmosphere;100%
With sodium methylate In methanol at 40℃; for 10h;100%
With sodium methylate In methanol at 40℃; for 10h;100%
With sodium hydrogencarbonate In ethanol for 3h; Substitution; Heating;
Stage #1: 2-mercaptoethylamine hydrochloride; 1,3-dibromo-propane With sodium methylate In methanol at 40℃; for 10h;
Stage #2: With sodium hydroxide In water at 20℃; for 10h;
(2S)-N-(4-hydroxy-5-methoxy-2-nitrobenzoyl)pyrrolidine-2-carboxaldehyde diethyl thioacetal
140647-02-5

(2S)-N-(4-hydroxy-5-methoxy-2-nitrobenzoyl)pyrrolidine-2-carboxaldehyde diethyl thioacetal

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1,1'-<<(propane-1,3-diyl)dioxy>bis<(2-nitro-5-methoxy-1,4-phenylene)carbonyl>>bis
140658-46-4

1,1'-<<(propane-1,3-diyl)dioxy>bis<(2-nitro-5-methoxy-1,4-phenylene)carbonyl>>bis

Conditions
ConditionsYield
With potassium carbonate In acetone for 48h; Etherification; Heating;100%
With potassium carbonate In acetone Heating;93%
1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

methyl-(2S)-N-[4-hydroxy-5-methoxy-2-nitrobenzoyl]pyrrolidine-2-carboxylate
175409-49-1

methyl-(2S)-N-[4-hydroxy-5-methoxy-2-nitrobenzoyl]pyrrolidine-2-carboxylate

C31H36N4O14
169258-71-3

C31H36N4O14

Conditions
ConditionsYield
With potassium carbonate In acetone for 48h; Heating;100%
1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1-[2-(pyridin-2-ylamino)ethyl]-1H-pyridin-2-one
420807-07-4

1-[2-(pyridin-2-ylamino)ethyl]-1H-pyridin-2-one

1-[2-(2-oxo-2H-pyridin-1-yl)ethyl]-1,2,3,4-tetrahydropyrido[1,2-a]pyrimidin-5-ylium bromide

1-[2-(2-oxo-2H-pyridin-1-yl)ethyl]-1,2,3,4-tetrahydropyrido[1,2-a]pyrimidin-5-ylium bromide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine for 18h; Heating;100%
1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1-[2-(5-chloropyridin-2-ylamino)ethyl]-4-methyl-1H-pyridin-2-one
420807-11-0

1-[2-(5-chloropyridin-2-ylamino)ethyl]-4-methyl-1H-pyridin-2-one

7-chloro-1-[2-(4-methyl-2-oxo-2H-pyridin-1-yl)ethyl]-1,2,3,4-tetrahydropyrido[1,2-a]pyrimidin-5-ylium bromide

7-chloro-1-[2-(4-methyl-2-oxo-2H-pyridin-1-yl)ethyl]-1,2,3,4-tetrahydropyrido[1,2-a]pyrimidin-5-ylium bromide

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine for 18h; Heating;100%
1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

C48H38N4O6P(1+)*F6P(1-)

C48H38N4O6P(1+)*F6P(1-)

bis(3-bromopropyloxy)[tetra-meso-(4-methoxyphenyl)porphyrinato]phosphorus(V) hexafluorophosphate

bis(3-bromopropyloxy)[tetra-meso-(4-methoxyphenyl)porphyrinato]phosphorus(V) hexafluorophosphate

Conditions
ConditionsYield
With 18-crown-6 ether; potassium carbonate In acetonitrile for 24h; Heating;100%
1-methyl-1H-imidazole
616-47-7

1-methyl-1H-imidazole

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1,1'-(propane-1,3-diyl)bis(3-methyl-1H-imidazol-3-ium) dibromide

1,1'-(propane-1,3-diyl)bis(3-methyl-1H-imidazol-3-ium) dibromide

Conditions
ConditionsYield
In tetrahydrofuran at 100℃;100%
In methanol at 0 - 55℃; for 64h; Inert atmosphere;98%
In acetonitrile at 20℃; for 168h;97%
[1-(3-hydroxypropyl)imidazolidin-2-ylidene]methanesulfonylacetonitrile
904677-19-6

[1-(3-hydroxypropyl)imidazolidin-2-ylidene]methanesulfonylacetonitrile

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

[1-(3-bromopropyl)-3-(3-hydroxypropyl)imidazolidin-2-ylidene]methanesulfonylacetonitrile
904677-20-9

[1-(3-bromopropyl)-3-(3-hydroxypropyl)imidazolidin-2-ylidene]methanesulfonylacetonitrile

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20 - 50℃; for 23h;100%
3-isopropyl-7-ethyl-3,7-dihydropurine-2,6-dione

3-isopropyl-7-ethyl-3,7-dihydropurine-2,6-dione

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1-(3-bromopropyl)-7-ethyl-3-isopropyl-3,7-dihydropurine-2,6-dione

1-(3-bromopropyl)-7-ethyl-3-isopropyl-3,7-dihydropurine-2,6-dione

Conditions
ConditionsYield
With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride at 100℃; for 3h;100%
1,10-Phenanthroline
66-71-7

1,10-Phenanthroline

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

6,7-dihydro-5H-[1,4]diazepino[1,2,3,4-l,m,n][1,10]phenanthroline-4,8-diium dibromide
15302-99-5

6,7-dihydro-5H-[1,4]diazepino[1,2,3,4-l,m,n][1,10]phenanthroline-4,8-diium dibromide

Conditions
ConditionsYield
In chlorobenzene at 70 - 120℃;100%
In nitrobenzene at 120℃;100%
for 12h; Reflux;99%
4-Trifluoromethoxyphenol
828-27-3

4-Trifluoromethoxyphenol

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1-(3-(4-trifluoromethoxy)phenoxy)propyl bromide
102793-82-8

1-(3-(4-trifluoromethoxy)phenoxy)propyl bromide

Conditions
ConditionsYield
With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate In water at 70℃; for 48h;100%
With potassium carbonate In N,N-dimethyl-formamide60%
2-(Boc-amino)-3-methylphenol
177342-60-8

2-(Boc-amino)-3-methylphenol

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

[2-(3-bromo-propoxy)-6-methyl-phenyl]-carbamic acid tert-butyl ester
1070972-64-3

[2-(3-bromo-propoxy)-6-methyl-phenyl]-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 55℃; for 2.5h;100%
1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

(+)-(aR)-7,7'-dihydroxy-8,8'-biquinolyl
914288-77-0, 914288-78-1, 829666-42-4

(+)-(aR)-7,7'-dihydroxy-8,8'-biquinolyl

C21H16N2O2
1062259-41-9

C21H16N2O2

Conditions
ConditionsYield
Stage #1: (-)-(aS)-7,7'-dihydroxy-8,8'-biquinolyl With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.416667h; Williamson synthesis;
Stage #2: 1,3-dibromo-propane In N,N-dimethyl-formamide at 20℃; for 47h; Williamson synthesis;
100%
1-phenylphospholane
3302-87-2

1-phenylphospholane

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1,3-bis(phenylphospholanium)propane dibromide

1,3-bis(phenylphospholanium)propane dibromide

Conditions
ConditionsYield
In acetonitrile at 60℃; for 48h; Inert atmosphere;100%
1,4-diaza-bicyclo[2.2.2]octane
280-57-9

1,4-diaza-bicyclo[2.2.2]octane

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1,1''-(propane-1,3-diyl)bis(1,4-diazabicyclo[2.2.2]-octan-1-ium)dibromide
97497-67-1

1,1''-(propane-1,3-diyl)bis(1,4-diazabicyclo[2.2.2]-octan-1-ium)dibromide

Conditions
ConditionsYield
In methanol at 20℃; for 24h;100%
In methanol at 20℃; for 20h;97%
In acetonitrile at 20℃; for 24h;74%
1-Butylimidazole
4316-42-1

1-Butylimidazole

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

1,3-bis(3-butylimidazolium-1-yl)propane dibromide

1,3-bis(3-butylimidazolium-1-yl)propane dibromide

Conditions
ConditionsYield
In tetrahydrofuran at 100℃;100%
In acetonitrile for 72h; Reflux;86%
In acetonitrile at 20℃; for 24h; Reflux;85%
(2S)-N-benzyl-2-(1H-imidazol-1-yl)-2,3-dimethylbutanamide
1234494-18-8

(2S)-N-benzyl-2-(1H-imidazol-1-yl)-2,3-dimethylbutanamide

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

3,3'-(1,3-propanediyl)bis(1-{(1S)-1-[(benzylamino)carbonyl]-1,2-dimethylpropyl}-3H-imidazol-1-ium) dibromide

3,3'-(1,3-propanediyl)bis(1-{(1S)-1-[(benzylamino)carbonyl]-1,2-dimethylpropyl}-3H-imidazol-1-ium) dibromide

Conditions
ConditionsYield
In toluene; acetonitrile at 100℃; Inert atmosphere;100%

1,3-Dibromopropane Chemical Properties

The Molecular Structure of Trimethylene bromide (CAS NO.109-64-8):


Empirical Formula: C3H6Br2
Molecular Weight: 201.8877 
IUPAC Name: 1,3-dibromopropane  
Appearance: colourless to slightly yellow liquid
Product Categories: Organics;DIBROMOALKANE;alpha,omega-Bifunctional Alkanes;alpha,omega-Dibromoalkanes;Monofunctional & alpha,omega-Bifunctional Alkanes
Nominal Mass: 200 Da
Average Mass: 201.8877 Da
Monoisotopic Mass: 199.88361 Da
Index of Refraction: 1.513
Molar Refractivity: 31.41 cm3
Molar Volume: 104.4 cm3
Surface Tension: 36 dyne/cm
Density: 1.933 g/cm3
Flash Point: 54.4 °C
Enthalpy of Vaporization: 38.69 kJ/mol
Boiling Point: 167 °C at 760 mmHg
Vapour Pressure: 2.29 mmHg at 25°C 
Storage temp: 2-8°C
Water Solubility: 1.7 g/L (30 ºC)
EINECS: 203-690-3
InChI
InChI=1/C3H6Br2/c4-2-1-3-5/h1-3H2
Smiles
C(CBr)CBr 
Synonyms: AI3-28592 ; CCRIS 6711 ; EINECS 203-690-3 ; HSDB 7408 ; NSC 62663 ; Trimethylene dibromide ; alpha,gamma-Dibromopropane ; Propane, 1,3-dibromo-   

1,3-Dibromopropane Uses

 Trimethylene bromide (CAS NO.109-64-8) can be used as Pharmaceutical intermediates, synthetic organic intermediates.

1,3-Dibromopropane Production

 Trimethylene bromide (CAS NO.109-64-8) can be prepared via the free radical addition between hydrogen bromide and allyl bromide .

1,3-Dibromopropane Toxicity Data With Reference

1.    

mmo-sat 10 µmol/plate

    ENMUDM    Environmental Mutagenesis. 2 (1980),59.
2.    

mma-sat 10 µmol/plate

    ENMUDM    Environmental Mutagenesis. 2 (1980),59.
3.    

ipr-mus LD50:473 mg/kg

    JPCEAO    Journal fuer Praktische Chemie. (Johann Ambrosius Barth Verlag, Postfach 109, DDR-701, Leipzig, Germany) V.1- 1834- 320 (1978),133.
4.    

rec-rbt LDLo:1000 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 34 (1928),223.

1,3-Dibromopropane Consensus Reports

Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

1,3-Dibromopropane Safety Profile

Moderately toxic by intraperitoneal and rectal routes. Mutation data reported. Irritating and narcotic in high concentration. When heated to decomposition it emits toxic fumes of Br. Used as an herbicide. See also BROMIDES.

Hazard Codes: IrritantXiHarmfulXnDangerousN
Risk Statements: 10-22-38-51/53-36/37/38
R10: Flammable
R22: Harmful if swallowed 
R51/53: Toxic to aquatic organisms, may cause long 
R36/37/38: Irritating to eyes, respiratory system and skin
Safety Statements: 16-26-36-61-24/25
S16: Keep away from sources of ignition - No smoking 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
S36: Wear suitable protective clothing 
S61: Avoid release to the environment. Refer to special instructions safety data sheet
S24/25: Avoid contact with skin and eyes  
RIDADR: UN 1993 3/PG 3

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