1-Bromo-2-methylpropane supplier

Name
1-Bromo-2-methylpropane
EINECS 201-141-2
CAS No. 78-77-3
Article Data70
CAS DataBase
Density 1.26 g/cm³
Solubility 0.51 g/L (18 °C) in water
Melting Point -119 °C
Formula C₄H₉Br
Boiling Point 90.7 °C at 760 mmHg
Molecular Weight 137.019
Flash Point 18.3 °C
Transport Information UN 2342 3/PG 2
Appearance clear liquid
Safety 16-23-37/39-26
Risk Codes 11-37-36/37/38
Molecular Structure
Hazard Symbols F,Xi
Synonyms 1-bromo-2-methyl-propane;Propane,1-bromo-2-methyl-;1-bromo-isobutane;Propane, 1-bromo-2-methyl-;Bromoisobutane;iso-Butyl bromide;Trimethyl bromomethane;1-bromo-2-methyl propane;iso-Butylbromide;Turmeric Colour;1-bromo-2-methyl propane 99%;
PSA 0.00000
LogP 2.03730

Synthetic route

: 29015-35-8, 651309-67-0
(i-C4H9)3SbBr2

A: 78-77-3
Isobutyl bromide

B: 251318-70-4
(isobutyl)2SbBr

Conditions

Conditions	Yield
heating at 220°C for 4 h; fractional distn. at 64-66°C at 0.1 Torr;	A n/a B 81%
heating at 220°C for 4 h; fractional distn. at 64-66°C at 0.1 Torr;	A n/a B 81%

: 78-83-1
2-methyl-propan-1-ol

: 78-77-3
Isobutyl bromide

Conditions

Conditions	Yield
With sulfuric acid; hydrogen bromide In water at 90 - 95℃;	42.9%
With phosphorus; bromine
With sulfuric acid; water; potassium bromide

: 161616-29-1
2-Isobutoxy-4-methyl-[1,3,2]dioxaborinane

A: 78-77-3
Isobutyl bromide

B: 107-80-2
1,3-dibromobutane

Conditions

Conditions	Yield
With aluminum tri-bromide In diethyl ether	A n/a B 41%

: 95093-86-0
2-isobutyl-4-methyl-1,3,2-dioxaborinane

A: 78-77-3
Isobutyl bromide

B: 107-80-2
1,3-dibromobutane

Conditions

Conditions	Yield
With aluminum tri-bromide In diethyl ether	A n/a B 25%

: 110-86-1
pyridine

: 507-19-7
t-butyl bromide

: 78-77-3
Isobutyl bromide

: 506-68-3
bromocyane

: 1741-85-1
1-isobutylsulfanyl-butane

A: 109-65-9
1-bromo-butane

B: 78-77-3
Isobutyl bromide

C: 591-84-4
isobutyl thiocyanate

Conditions

Conditions	Yield
at 70℃; im Rohr;

...Expand

: 118725-89-6
dibromophosphoric acid isobutyl ester

: 78-83-1
2-methyl-propan-1-ol

: 78-77-3
Isobutyl bromide

Conditions

Conditions	Yield
at 17℃;

: 108899-28-1
bromophosphoric acid diisobutyl ester

: 78-77-3
Isobutyl bromide

Conditions

Conditions	Yield
at 100℃;

: 78-83-1
2-methyl-propan-1-ol

A: 78-77-3
Isobutyl bromide

B: 594-34-3
1,2-dibromo-2-methyl-propane

Conditions

Conditions	Yield
With naphthalene; bromine

: 507-19-7
t-butyl bromide

: 78-77-3
Isobutyl bromide

Conditions

Conditions	Yield
at 210 - 220℃;
at 205 - 240℃; Geschwindigkeit;
at 210 - 220℃; im Rohr;
Gleichgewicht des Systems Isobutylbromid-tert.-Butylbromid liegt bei ca. 76prozent tert.-Bromid;

: N-isobutyl-aniline; hydrobromide

A: 78-77-3
Isobutyl bromide

B: 769-92-6
4-tert-Butylaniline

C: 115-11-7
isobutene

Conditions

Conditions	Yield
at 300℃;

...Expand

: 64-19-7
acetic acid

: 115-11-7
isobutene

A: 507-19-7
t-butyl bromide

B: 78-77-3
Isobutyl bromide

Conditions

Conditions	Yield
With hydrogen bromide

...Expand

: 513-36-0
isobutyryl chloride

A: 507-19-7
t-butyl bromide

B: 78-77-3
Isobutyl bromide

Conditions

Conditions	Yield
With aluminium trichloride; hydrogen bromide

: 2465-56-7
methylene

: 75-26-3
isopropyl bromide

A: 507-19-7
t-butyl bromide

B: 78-77-3
Isobutyl bromide

C: 78-76-2, 5787-31-5
s-butyl bromide

...Expand

: 115-11-7
isobutene

A: 507-19-7
t-butyl bromide

B: 78-77-3
Isobutyl bromide

Conditions

Conditions	Yield
With hydrogen bromide; acetic acid

: 115-11-7
isobutene

: 78-77-3
Isobutyl bromide

Conditions

Conditions	Yield
With hydrogen bromide
With ascaridole; hydrogen bromide

: 75-21-8
oxirane

: 78-77-3
Isobutyl bromide

Conditions

Conditions	Yield
With Cu(i-BuBr)2+ Thermodynamic data; free energie for exchange of both ligands;

: 75-28-5
Isobutane

A: 507-19-7
t-butyl bromide

B: 78-77-3
Isobutyl bromide

Conditions

Conditions	Yield
With norborn-2-ene; N-bromobis(trimethylsilyl)amine at 44.9℃; for 2h; Product distribution; Mechanism; Irradiation; variation of temperature, time, reagent concentration, initiation method;
With N-Bromosuccinimide In dichloromethane at 15℃; Product distribution; Irradiation; CH2CCl2; influence of additive - BrCCl3;
With N-Bromosuccinimide; 1,1-Dichloroethylene In dichloromethane at 14 - 15℃;	A 0.133 mmol B 0.084 mmol

: 75-28-5
Isobutane

A: 507-20-0
tertiary butyl chloride

B: 507-19-7
t-butyl bromide

C: 78-77-3
Isobutyl bromide

D: 513-36-0
isobutyryl chloride

E: 75-65-0
tert-butyl alcohol

Conditions

Conditions	Yield
With IVTPP(OIPh)>2O; BrMnIIITPP In chlorobenzene at 25℃; Product distribution; Mechanism;	A 6 % Chromat. B 18 % Chromat. C 2 % Chromat. D 2 % Chromat. E 11 % Chromat.

...Expand

: 75-28-5
Isobutane

A: 507-20-0
tertiary butyl chloride

B: 507-19-7
t-butyl bromide

C: 78-77-3
Isobutyl bromide

D: 75-65-0
tert-butyl alcohol

Conditions

Conditions	Yield
With (5,10,15,20-tetraphenylporphyrinato)manganese(III) chloride; IVTPP(OIPh)>2O In chlorobenzene at 25℃; Product distribution; Mechanism;	A 7 % Chromat. B 11 % Chromat. C 2 % Chromat. D 10 % Chromat.

...Expand

: 75-28-5
Isobutane

A: 507-19-7
t-butyl bromide

B: 78-77-3
Isobutyl bromide

C: 75-65-0
tert-butyl alcohol

Conditions

Conditions	Yield
With IVTPP(OIPh)>2O In chlorobenzene at 25℃; for 1h; Product distribution; Mechanism; further reagents (BrMnIIITPP);	A 13 % Chromat. B 2 % Chromat. C 11 % Chromat.

...Expand

: 513-38-2
Isobutyl iodide

: 78-77-3
Isobutyl bromide

Conditions

Conditions	Yield
With pyridine; tributyltin bromide at 125℃; Thermodynamic data; Equilibrium constant; Δ G;	33 % Spectr.

: 513-36-0
isobutyryl chloride

: 78-77-3
Isobutyl bromide

Conditions

Conditions	Yield
With pyridine; tributyltin bromide at 125℃; Thermodynamic data; Equilibrium constant; Δ G;

: 75-26-3
isopropyl bromide

: 78-77-3
Isobutyl bromide

Conditions

Conditions	Yield
With Cu(i-BuBr)2+ Thermodynamic data; free energie for exchange of both ligands;

: 106-97-8
n-butane

A: 507-19-7
t-butyl bromide

B: 78-77-3
Isobutyl bromide

C: 78-76-2, 5787-31-5
s-butyl bromide

Conditions

Conditions	Yield
With 2AlBr3*CBr4; bromine at -20℃; for 2h; Title compound not separated from byproducts;
With 2AlBr3*CBr4; bromine In various solvent(s) at -20℃; for 2h; Yields of byproduct given. Title compound not separated from byproducts;
With 2AlBr3*CBr4; bromine at -20℃; for 2h; Yield given. Title compound not separated from byproducts;
With 2AlBr3*CBr4; bromine In various solvent(s) at -20℃; for 2h; Yield given. Title compound not separated from byproducts;

...Expand

: 1605-73-8
t-Butyl radical

: 78-77-3
Isobutyl bromide

Conditions

Conditions	Yield
With helium; hydrogen bromide at 27.9 - 393.9℃; Kinetics; Thermodynamic data; Irradiation; ΔS, ΔH, ΔG;

: 4630-45-9
isobutyl radical

: 78-77-3
Isobutyl bromide

Conditions

Conditions	Yield
With helium; hydrogen bromide at 27.9 - 276.9℃; Kinetics; Irradiation; ΔS, ΔG, ΔH;

: 10035-10-6, 12258-64-9
hydrogen bromide

: 115-11-7
isobutene

: 78-77-3
Isobutyl bromide

Conditions

Conditions	Yield
UV-Licht.Irradiation;
UV-Licht.Irradiation;

: 512-85-6
ascaridole

: 10035-10-6, 12258-64-9
hydrogen bromide

: 115-11-7
isobutene

: 78-77-3
Isobutyl bromide

...Expand

: 7446-70-0
aluminium trichloride

: 10035-10-6, 12258-64-9
hydrogen bromide

: 513-36-0
isobutyryl chloride

A: 507-19-7
t-butyl bromide

B: 78-77-3
Isobutyl bromide

...Expand

: 78-77-3
Isobutyl bromide

: 1074-82-4
potassium phtalimide

: 304-17-6
N-isopropylphthalimide

Conditions

Conditions	Yield
[2.2.2]cryptande In tetrahydrofuran for 0.25h;	100%

: 78-77-3
Isobutyl bromide

: 26257-08-9
methanethiol

sodium methoxide: sodium methoxide

: 95676-01-0
(2-Isobutylsulfanylmethyl-phenyl)-methanol

Conditions

Conditions	Yield
In methanol for 48h; Ambient temperature;	100%

...Expand

: 78-77-3
Isobutyl bromide

: 3,6-dibromo-8-methoxyimidazo[1,2-a]pyrazine

: 6-bromo-3-(isobutyl)-8-methoxyimidazo[1,2-a]pyrazine

Conditions

Conditions	Yield
Stage #1: 3,6-dibromo-8-methoxyimidazo[1,2-a]pyrazine In tetrahydrofuran; hexane at -75℃; for 0.25h; Metallation; Stage #2: Isobutyl bromide In tetrahydrofuran; hexane at -75 - 20℃; for 0.25h; Substitution;	100%

: 78-77-3
Isobutyl bromide

: 202743-43-9
3-butenyl(1,3-dithian-2-yl)methylphenylsilane

: 202743-44-0
3-butenyl[2-(2-methylpropyl)-1,3-dithian-2-yl]methylphenylsilane

Conditions

Conditions	Yield
Stage #1: 3-butenyl(1,3-dithian-2-yl)methylphenylsilane With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 3h; Stage #2: Isobutyl bromide In tetrahydrofuran; hexane at -78 - 20℃; Further stages.;	100%

: 78-77-3
Isobutyl bromide

: 100-47-0
benzonitrile

: 582-62-7
3-methyl-1-phenylbutan-1-one

Conditions

Conditions	Yield
Stage #1: Isobutyl bromide With iodine; magnesium In diethyl ether Stage #2: benzonitrile In diethyl ether for 6h; Heating;	100%
Stage #1: Isobutyl bromide With iodine; magnesium In diethyl ether Inert atmosphere; Stage #2: benzonitrile In diethyl ether for 6h; Grignard reaction; Reflux; Stage #3: With sulfuric acid; water In diethyl ether Heating;	100%
Stage #1: Isobutyl bromide With iodine; magnesium In diethyl ether for 1h; Inert atmosphere; Reflux; Stage #2: benzonitrile In diethyl ether at 20℃; for 0.5h; Reflux; Inert atmosphere;	29%

: 288-13-1
NH-pyrazole

: 78-77-3
Isobutyl bromide

: 725746-81-6
1-isobutyl-1H-pyrazole

Conditions

Conditions	Yield
With sodium hydroxide; tetrabutylammomium bromide In water; methyl cyclohexane at 110℃; for 5.5h; Product distribution / selectivity; Heating / reflux;	100%
With potassium hydroxide In ethanol at 78℃; for 1.5h;	64%

: 78-77-3
Isobutyl bromide

: 14199-15-6
Methyl 4-hydroxyphenylacetate

: 2-(4-isobutyloxyphenyl)acetic acid methyl ester

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20 - 80℃; for 73h;	100%
Stage #1: Methyl 4-hydroxyphenylacetate With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 1h; Stage #2: Isobutyl bromide In N,N-dimethyl-formamide at 80℃; for 72h; Reagent/catalyst;	94.6%
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 6h; Temperature;	94.02%

: 78-77-3
Isobutyl bromide

: 6725-44-6
methyl 2-(3,4-dichlorophenyl)acetate

: 300356-82-5
2-(3,4-dichlorophenyl)-4-methyl-pentanoic acid methyl ester

Conditions

Conditions	Yield
Stage #1: methyl 2-(3,4-dichlorophenyl)acetate With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.75h; Inert atmosphere; Stage #2: Isobutyl bromide In tetrahydrofuran at -78 - 25℃; Inert atmosphere;	100%

: 4010-81-5
4-(2-chloro-9H-purin-6-yl)morpholine

: 78-77-3
Isobutyl bromide

: 1198171-89-9
2-chloro-9-isobutyl-6-morpholin-4-yl-9H-purine

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 5h;	100%

: 78-77-3
Isobutyl bromide

: 50773-56-3
3-benzyloxy-4-hydroxybenzaldehyde

: 1234500-50-5
4-isobutoxy-3-benzyloxybenzaldehyde

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 20h;	100%

: 21642-98-8
2-hydroxy-4-methoxypyridine-3-carbonitrile

: 78-77-3
Isobutyl bromide

: 1-isobutyl-4-methoxy-2-oxo-1,2-dihydropyridine-3-carbonitrile

Conditions

Conditions	Yield
With potassium carbonate In acetonitrile at 100℃; for 16h;	100%

: 78-77-3
Isobutyl bromide

: 33288-79-8
4,4'-dihydroxybenzil

: 1,2-bis(4-isobutoxyphenyl)ethane-1,2-dione

Conditions

Conditions	Yield
With tetrabutylammomium bromide; potassium carbonate In N,N-dimethyl-formamide at 130℃;	100%

: 78-77-3
Isobutyl bromide

: 767-00-0
4-cyanophenol

: 5203-15-6
4-(2-methylpropoxy)benzonitrile

Conditions

Conditions	Yield
With potassium iodide In N,N-dimethyl-formamide at 60℃; for 10h; Reagent/catalyst; Solvent; Temperature;	100%
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 80℃; for 6h;	98.5%
With tetra-(n-butyl)ammonium iodide In N,N-dimethyl-formamide at 70℃; for 18h;	98%

: 78-77-3
Isobutyl bromide

: 636-93-1
5-nitroguaiacol

: 185145-95-3
2-Isobutoxy-1-methoxy-4-nitro-benzene

Conditions

Conditions	Yield
With tetra-(n-butyl)ammonium iodide; potassium carbonate In acetone for 48h; Heating;	99.5%

: 78-77-3
Isobutyl bromide

: 13036-02-7
Dimethyl 5-hydroxyisophthalate

: 1185753-91-6
dimethyl 5-(isobutyloxy)isophthalate

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 40℃; for 20h;	99.5%
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 60℃; for 72h; Inert atmosphere;	94%

: 78-77-3
Isobutyl bromide

: 926-62-5
isobutylmagnesium bromide

Conditions

Conditions	Yield
With iodine; magnesium In diethyl ether for 0.75h; Inert atmosphere; Cooling with ice; Reflux;	99%
With magnesium In diethyl ether Thermodynamic data; -ΔH(reaction);
With magnesium In diethyl ether

: 78-77-3
Isobutyl bromide

: 90-02-8
salicylaldehyde

: 81995-32-6
2-(i-butoxy)benzaldehyde

Conditions

Conditions	Yield
With potassium carbonate In tetrahydrofuran at 20 - 40℃; for 16h; Inert atmosphere;	99%
With potassium carbonate In N,N-dimethyl-formamide at 40℃; for 20h; Inert atmosphere;	99%
With potassium carbonate In N,N-dimethyl-formamide at 40℃; for 20h; Inert atmosphere;	99%

: diferrocenyl ditelluride

: 78-77-3
Isobutyl bromide

: 340681-36-9
ferrocenyl i-butyl telluride

Conditions

Conditions	Yield
With sodium tetrahydroborate In ethanol (N2); Fe complex reacted with NaBH4 in EtOH; reacted with alkyl halide in EtOH;	99%

: 78-77-3
Isobutyl bromide

: 26153-38-8
3,5-dihydroxybenzaldehyde

: 1051932-53-6
3,5-diisobutoxybenzaldehyde

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 55℃; for 2.5h;	99%

: 78-77-3
Isobutyl bromide

: 1034155-43-5
3-(5-iodo-1H-indazol-1-yl)benzoic acid

: 1196452-46-6
isobutyl 3-(5-iodo-1H-indazol-1-yl)benzoate

Conditions

Conditions	Yield
With sodium carbonate In 1-methyl-pyrrolidin-2-one at 40 - 55℃;	99%
Stage #1: 3-(5-iodo-1H-indazol-1-yl)benzoic acid With sodium carbonate In 1-methyl-pyrrolidin-2-one at 40℃; Stage #2: Isobutyl bromide In 1-methyl-pyrrolidin-2-one at 40 - 55℃;	99%

: 626-72-2, 870-93-9, 6027-15-2, 7093-69-8, 462-10-2
L-homocystine

: 78-77-3
Isobutyl bromide

: 13073-23-9
(2S)-2-amino-4-[(2-methylpropyl)sulfanyl]butanoic acid

Conditions

Conditions	Yield
With ammonia; sodium at -78℃;	99%

: 78-77-3
Isobutyl bromide

: 3344-77-2
12-bromododecanol

: 20194-48-3
14-methyl-1-pentadecanol

Conditions

Conditions	Yield
Stage #1: Isobutyl bromide With magnesium In tetrahydrofuran for 1.5h; Reflux; Stage #2: 12-bromododecanol With dilithium tetrachlorocuprate In tetrahydrofuran at -78 - 20℃; for 1.66667h;	99%

: 78-77-3
Isobutyl bromide

: 622-47-9
4-tolylacetic acid

: 4-methyl-2-(p-tolyl)pentanoic acid

Conditions

Conditions	Yield
Stage #1: 4-tolylacetic acid With n-butyllithium In tetrahydrofuran at 0℃; for 1.5h; Inert atmosphere; Stage #2: Isobutyl bromide In tetrahydrofuran for 0.25h; Inert atmosphere;	99%

: 78-77-3
Isobutyl bromide

: 161798-01-2
ethyl 2‐(3‐formyl‐4‐hydroxyphenyl)‐4‐methylthiazole‐5‐carboxylate

: febuxostat

Conditions

Conditions	Yield
With potassium carbonate; N,N-dimethyl-formamide In toluene at 105℃; for 4h;	98.71%

: 78-77-3
Isobutyl bromide

: 161798-02-3
ethyl-2-(3-cyano-4-hydroxy phenyl)-4-methyl thiozole-5-carboxylate

: 160844-75-7
2-(3-cyano-4-isobutyloxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl ester

Conditions

Conditions	Yield
With potassium carbonate; potassium iodide In ethyl acetate at 65 - 70℃; for 5h; Temperature; Solvent; Reagent/catalyst;	98.2%
With potassium carbonate In N,N-dimethyl-formamide at 75℃; for 8h;	92.9%
With potassium carbonate In 1-methyl-pyrrolidin-2-one at 90℃; for 3h;	88%
With potassium carbonate In 1-methyl-pyrrolidin-2-one at 90℃; for 3h;	88%
With potassium carbonate In N,N-dimethyl-formamide at 75℃; for 15h;	2.28 g

: 78-77-3
Isobutyl bromide

: 123-08-0
4-hydroxy-benzaldehyde

: 18962-07-7
4-isobutoxybenzaldehyde

Conditions

Conditions	Yield
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 70℃; for 3h; Inert atmosphere;	98%
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 85℃; for 6h;	96%
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 85℃; for 6h;	95%

: 78-77-3
Isobutyl bromide

: 4810-78-0
4-isopentylpyridine

Conditions

Conditions	Yield
Stage #1: picoline With n-butyllithium In tetrahydrofuran at -78 - 45℃; for 2h; Stage #2: Isobutyl bromide In tetrahydrofuran at -78 - 20℃; Stage #3: With water In tetrahydrofuran	98%

: 78-77-3
Isobutyl bromide

: 16643-09-7
trimethylstannyl sodium

: 1118-10-1
isobutyl-trimethyl stannane

Conditions

Conditions	Yield
In tetrahydrofuran 0°C in N2-atmosphere; various yields for various conditions;	98%
In tetrahydrofuran byproducts: NaBr; under argon, equimolar amounts, at 0°C; GLC;	82%

: 78-77-3
Isobutyl bromide

: 29865-90-5
3-hydroxy-4,5-dimethoxybenzaldehyde

: 1351593-96-8
3-isobutoxy-4,5-dimethoxybenzaldehyde

Conditions

Conditions	Yield
Stage #1: 3-hydroxy-4,5-dimethoxybenzaldehyde With caesium carbonate In N,N-dimethyl-formamide for 0.166667h; Inert atmosphere; Stage #2: Isobutyl bromide In N,N-dimethyl-formamide at 20℃;	98%

: 78-77-3
Isobutyl bromide

: 4-(4-bromo-2-fluorophenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

: 4-(4-bromo-2-fluorophenyl)-1-isobutyl-1H-1,2,4-triazol-5(4H)-one

Conditions

Conditions	Yield
Stage #1: 4-(4-bromo-2-fluorophenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one With potassium hydroxide In N,N-dimethyl-formamide at 20℃; for 0.166667h; Stage #2: Isobutyl bromide In N,N-dimethyl-formamide at 60℃; for 12h;	98%

1-Bromo-2-methylpropane Consensus Reports

EPA Genetic Toxicology Program. Reported in EPA TSCA Inventory.

1-Bromo-2-methylpropane Standards and Recommendations

DOT Classification: 3; Label: Flammable Liquid

1-Bromo-2-methylpropane Specification

The IUPAC name of this chemical is 1-bromo-2-methylpropane. With the CAS registry number 78-77-3, it is also named as Bromoisobutane; iso-Butyl bromide. The product's categories are organics and alkyl bromide. It is clear liquid which is slightly soluble in water, and miscible with ethanol, ether and other organic solvents. In addition, it is flammable by fire, heat and oxidants. When heated to decomposition it emits toxic fumes of Br-. The storage environment should be ventilate, low-temperature and dry. Keep it separate from oxidant and acid.

The other characteristics of this product can be summarized as: (1)ACD/LogP: 2.56; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.56; (4)ACD/LogD (pH 7.4): 2.56; (5)ACD/BCF (pH 5.5): 51.78; (6)ACD/BCF (pH 7.4): 51.78; (7)ACD/KOC (pH 5.5): 587; (8)ACD/KOC (pH 7.4): 587; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 1; (12)Index of Refraction: 1.436; (13)Molar Refractivity: 28.27 cm³; (14)Molar Volume: 108.1 cm³; (15)Polarizability: 11.2×10^-24 cm³; (16)Surface Tension: 24.6 dyne/cm; (17)Enthalpy of Vaporization: 31.33 kJ/mol; (18)Vapour Pressure: 62.9 mmHg at 25°C; (19)Rotatable Bond Count: 1; (20)Exact Mass: 135.988763; (21)MonoIsotopic Mass: 135.988763; (22)Heavy Atom Count: 5.

Preparation of 1-Bromo-2-methylpropane: It can be obtained by 2-isobutoxy-4-methyl-[1,3,2]dioxaborinane with anhyd. AlBr₃ in solvent diethyl ether. The yield is 41% and this reaction can get another product 1,3-dibromo-butane.

Uses of 1-Bromo-2-methylpropane: It is used as solvent, organic synthesis and pharmaceutical intermediate. It can react with piperazine to get 1-isobutyl-piperazine. This reaction needs reagent toluene at temperature of 90 °C.

When you are using this chemical, please be cautious about it as the following:
It is highly flammable, so keep it away from sources of ignition.. And it is irritating to eyes, respiratory system and skin, so people should not breathe vapour. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable gloves and eye/face protection.

People can use the following data to convert to the molecule structure.
1. SMILES: BrCC(C)C;
2. InChI: InChI=1/C4H9Br/c1-4(2)3-5/h4H,3H2,1-2H3.

The following are the toxicity data which has been tested.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mammal (species unspecified)	LC50	inhalation	50500mg/m³ (50500mg/m³)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 18(4), Pg. 55, 1974.
mouse	LD50	intraperitoneal	1660mg/kg (1660mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 20(12), Pg. 52, 1976.

Product Name

1-Bromo-2-methylpropane

Synthetic route

1-Bromo-2-methylpropane Consensus Reports

1-Bromo-2-methylpropane Standards and Recommendations

1-Bromo-2-methylpropane Specification

Related Products

Hot Products