1-Chloro-1,1-difluoroethane supplier

Name
1-Chloro-1,1-difluoroethane
EINECS 200-891-8
CAS No. 75-68-3
Article Data40
CAS DataBase
Density 1.198 g/cm³
Solubility
Melting Point -131 °C
Formula C₂H₃ClF₂
Boiling Point -9 °C
Molecular Weight 100.496
Flash Point
Transport Information UN 2517 2.1
Appearance colourless gas
Safety 38-59
Risk Codes 12-59
Molecular Structure
Hazard Symbols F+, N, Xi
Synonyms 1,1-Difluoro-1-chloroethane;CFC 142b;Daiflon 142b;Dymel 142;F 142b;FC142b;FKW 142b;Freon 142b;Fron 142b;Genetron 101;Genetron 142b;HCFC 142b;HFA 142b;Propellant 142B;R 142b;Solkane 142b;a-Chloroethylidene fluoride;
PSA 0.00000
LogP 1.83790

Synthetic route

: 75-35-4
1,1-Dichloroethylene

A: 420-46-2
2,2,2-trifluoroethanol

B: 75-68-3
1-Chloro-1,1-difluoroethane

C: 1717-00-6
HCFC-141b

Conditions

Conditions	Yield
With hydrogen fluoride; SbCl5 on Carbon at 100℃; under 760.051 Torr; for 0.00277778h;	A 80% B n/a C n/a

...Expand

: 75-37-6
1,1-difluoroethane

: 75-68-3
1-Chloro-1,1-difluoroethane

Conditions

Conditions	Yield
With chlorine In gas at 21.9℃; under 760 Torr; for 0.000666667h; Irradiation; time history of ignition;
bei der Photochlorierung;
beim Chlorieren im Sonnenlicht;

: 75-37-6
1,1-difluoroethane

A: 75-68-3
1-Chloro-1,1-difluoroethane

B: 1649-08-7
1,2-dichloro-1,1-difluoroethane

Conditions

Conditions	Yield
beim Chlorieren im Sonennlicht;

: 71-55-6
1,1,1-trichloroethane

: 75-68-3
1-Chloro-1,1-difluoroethane

Conditions

Conditions	Yield
With hydrogen fluoride at 200℃; under 175051 Torr;
With antimony dichloride trifluoride; antimony(III) fluoride

: 75-35-4
1,1-Dichloroethylene

A: 420-46-2
2,2,2-trifluoroethanol

B: 75-68-3
1-Chloro-1,1-difluoroethane

Conditions

Conditions	Yield
With hydrogen fluoride; diphenylamine at 180 - 195℃; unter Druck;

: 75-35-4
1,1-Dichloroethylene

: 75-68-3
1-Chloro-1,1-difluoroethane

Conditions

Conditions	Yield
With hydrogen fluoride; diphenylamine at 140℃; im Autoklaven;

: 1717-00-6
HCFC-141b

A: 420-46-2
2,2,2-trifluoroethanol

B: 75-68-3
1-Chloro-1,1-difluoroethane

C: 2317-91-1
1-chloro-1-fluoroethane

D: 75-35-4
1,1-Dichloroethylene

E: 64-19-7
acetic acid

Conditions

Conditions	Yield
fluorinated γ-alumina at 300℃; Product distribution; other temperatures; also with HCl or HF as reagents;

...Expand

: 2317-91-1
1-chloro-1-fluoroethane

A: 420-46-2
2,2,2-trifluoroethanol

B: 75-68-3
1-Chloro-1,1-difluoroethane

C: 75-38-7
Vinylidene fluoride

D: 64-19-7
acetic acid

Conditions

Conditions	Yield
fluorinated γ-alumina at 300℃; Product distribution; other temperatures;

...Expand

: 2317-91-1
1-chloro-1-fluoroethane

A: 420-46-2
2,2,2-trifluoroethanol

B: 75-68-3
1-Chloro-1,1-difluoroethane

C: 75-38-7
Vinylidene fluoride

D: 75-35-4
1,1-Dichloroethylene

E: 64-19-7
acetic acid

Conditions

Conditions	Yield
With hydrogenchloride; fluorinated γ-alumina at 300℃; Product distribution; other temperatures;

...Expand

: 1717-00-6
HCFC-141b

: 75-68-3
1-Chloro-1,1-difluoroethane

Conditions

Conditions	Yield
With hydrogen fluoride Heating;

: 71-55-6
1,1,1-trichloroethane

A: 420-46-2
2,2,2-trifluoroethanol

B: 75-68-3
1-Chloro-1,1-difluoroethane

C: 1717-00-6
HCFC-141b

D: 75-72-9
chlorotrifluoromethane

E: 75-35-4
1,1-Dichloroethylene

Conditions

Conditions	Yield
With fluorinated indium(III) oxide Product distribution; Ambient temperature; further reagent: fluorinated gallium(III) oxide;

...Expand

: 75-35-4
1,1-Dichloroethylene

A: 75-68-3
1-Chloro-1,1-difluoroethane

B: 1717-00-6
HCFC-141b

C: 75-72-9
chlorotrifluoromethane

Conditions

Conditions	Yield
With fluorinated gallium(III) oxide Product distribution; Ambient temperature;

...Expand

: 594-72-9
1,1-dichloro-1-nitroethane

: 7664-39-3
hydrogen fluoride

antimony dichloride trifluoroide: antimony dichloride trifluoroide

: 75-68-3
1-Chloro-1,1-difluoroethane

Conditions

Conditions	Yield
at 115℃;

...Expand

: 75-35-4
1,1-Dichloroethylene

: 122-39-4
diphenylamine

HF (6 mol): HF (6 mol)

A: 420-46-2
2,2,2-trifluoroethanol

B: 75-68-3
1-Chloro-1,1-difluoroethane

Conditions

Conditions	Yield
at 140 - 210℃; unter Druck;entstehen je nach der Reaktionsdauer wechselnde Mengen;

...Expand

: 71-55-6
1,1,1-trichloroethane

: 7664-39-3
hydrogen fluoride

A: 420-46-2
2,2,2-trifluoroethanol

B: 75-68-3
1-Chloro-1,1-difluoroethane

C: 1717-00-6
HCFC-141b

...Expand

: 71-55-6
1,1,1-trichloroethane

: 7664-39-3
hydrogen fluoride

: 7647-18-9
antimonypentachloride

A: 420-46-2
2,2,2-trifluoroethanol

B: 75-68-3
1-Chloro-1,1-difluoroethane

C: 1717-00-6
HCFC-141b

...Expand

: 71-55-6
1,1,1-trichloroethane

: 7783-56-4
antimony(III) fluoride

A: 420-46-2
2,2,2-trifluoroethanol

B: 75-68-3
1-Chloro-1,1-difluoroethane

C: 1717-00-6
HCFC-141b

...Expand

: 71-55-6
1,1,1-trichloroethane

chlorinated SbF3: chlorinated SbF3

A: 420-46-2
2,2,2-trifluoroethanol

B: 75-68-3
1-Chloro-1,1-difluoroethane

C: 1717-00-6
HCFC-141b

...Expand

: 75-35-4
1,1-Dichloroethylene

HF (4 mol): HF (4 mol)

A: 75-68-3
1-Chloro-1,1-difluoroethane

B: 1717-00-6
HCFC-141b

C: 71-55-6
1,1,1-trichloroethane

Conditions

Conditions	Yield
at 65℃; unter Druck;

...Expand

: 75-09-2
dichloromethane

A: 3228-99-7
pentaerythrityl tetrachloride

B: 75-28-5
Isobutane

C: 75-68-3
1-Chloro-1,1-difluoroethane

D: 1717-00-6
HCFC-141b

E: 1649-08-7
1,2-dichloro-1,1-difluoroethane

F: 76-01-7
pentachloroethane

G (ClCH2)3CCl: (ClCH2)3CCl

Conditions

Conditions	Yield
With fluorinated gallium(III) oxide Product distribution; Mechanism; Ambient temperature;

...Expand

: 75-68-3
1-Chloro-1,1-difluoroethane

: 420-46-2
2,2,2-trifluoroethanol

Conditions

Conditions	Yield
at 200℃; for 2h; Conversion of starting material;	100%
With hydrogen fluoride; chlorine; antimonypentachloride at 15 - 20℃; under 6750.68 Torr;	97%
With hydrogen fluoride; chromium(III) water-soluble salt; graphite; magnesium oxide; water; mixture of, dried at 150 C, hydrofluorinated at 200-350 C at 200℃; under 7500.75 Torr; Continious process;
With neodymium(III) oxide; hydrogen fluoride; antimony pentafluoride at 10℃; under 2250.23 Torr; Reagent/catalyst; Large scale;

: 75-68-3
1-Chloro-1,1-difluoroethane

: 34598-49-7
5-Bromo-1-indanone

: 5-(1,1-difluoroethyl)-2,3-dihydro-1H-inden-1-one

Conditions

Conditions	Yield
With dmap; bis(tricyclohexylphosphine)nickel(II) dichloride; 4,4'-diamino-2,2'-bipyridyl; magnesium chloride; zinc In dimethyl sulfoxide at 110℃; for 10h; Schlenk technique;	83%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 3466-32-8
4-bromoohenyl methyl sulfone

: 1-(1,1-difluoroethyl)-4-(methylsulfonyl)benzene

Conditions

Conditions	Yield
With dmap; bis(tricyclohexylphosphine)nickel(II) dichloride; 4,4'-diamino-2,2'-bipyridyl; magnesium chloride; zinc In dimethyl sulfoxide at 110℃; for 10h; Schlenk technique;	80%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 99-90-1
para-bromoacetophenone

: 1-(4-(1,1-difluoroethyl)phenyl)ethan-1-one

Conditions

Conditions	Yield
With dmap; bis(tricyclohexylphosphine)nickel(II) dichloride; 4,4'-diamino-2,2'-bipyridyl; magnesium chloride; zinc In dimethyl sulfoxide at 110℃; for 10h; Schlenk technique;	78%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 1591-31-7
4-iodo-biphenyl

: 4-(1,1-difluoroethyl)-1,1’-biphenyl

Conditions

Conditions	Yield
With dmap; bis(tricyclohexylphosphine)nickel(II) dichloride; 4,4'-diamino-2,2'-bipyridyl; magnesium chloride; zinc In dimethyl sulfoxide at 110℃; for 10h; Schlenk technique;	74%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 90-90-4
(4-bromophenyl)(phenyl)methanone

: (4-(1,1-difluoroethyl)phenyl)(phenyl)methanone

Conditions

Conditions	Yield
With dmap; bis(tricyclohexylphosphine)nickel(II) dichloride; 4,4'-diamino-2,2'-bipyridyl; magnesium chloride; zinc In dimethyl sulfoxide at 110℃; for 10h; Schlenk technique;	73%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 92-66-0
4-bromo-1,1'-biphenyl

: 4-(1,1-difluoroethyl)-1,1’-biphenyl

Conditions

Conditions	Yield
With dmap; bis(tricyclohexylphosphine)nickel(II) dichloride; 4,4'-diamino-2,2'-bipyridyl; magnesium chloride; zinc In dimethyl sulfoxide at 110℃; for 10h; Schlenk technique;	72%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 5122-94-1
4-biphenylboronic acid

: 4-(1,1-difluoroethyl)-1,1’-biphenyl

Conditions

Conditions	Yield
With dmap; bis(triphenylphosphine)nickel(II) chloride; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 5h; Reagent/catalyst; Schlenk technique; Inert atmosphere;	70%
With dmap; trans-[Ni(Cl)2(PPh3)2]; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 12h; Catalytic behavior; Reagent/catalyst; Solvent; Suzuki-Miyaura Coupling;	70%

: 419536-33-7
4-(carbazol-9-yl)phenylboronic acid

: 75-68-3
1-Chloro-1,1-difluoroethane

: 9-(4-(1,1-difluoroethyl)phenyl)-9H-carbazole

Conditions

Conditions	Yield
With dmap; trans-[Ni(Cl)2(PPh3)2]; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 5h; Suzuki-Miyaura Coupling;	62%
With dmap; bis(triphenylphosphine)nickel(II) chloride; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 5h; Schlenk technique; Inert atmosphere;	59%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 49562-28-9
fenofibrate

: 2-(4-(4-(1,1-difluoroethyl)benzoyl)phenoxy)-2-methylpropionoic acid isopropyl ester

Conditions

Conditions	Yield
With dmap; bis(tricyclohexylphosphine)nickel(II) dichloride; 4,4'-diamino-2,2'-bipyridyl; magnesium chloride; zinc In dimethyl sulfoxide at 110℃; for 10h; Schlenk technique;	62%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 153035-62-2
(4'-ethyl[1,1'-biphenyl]-4-yl)boronic acid

: 4-(1,1-difluoroethyl)-4'-ethyl-1,1'-biphenyl

Conditions

Conditions	Yield
With dmap; trans-[Ni(Cl)2(PPh3)2]; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 5h; Suzuki-Miyaura Coupling;	61%
With dmap; bis(triphenylphosphine)nickel(II) chloride; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 5h; Schlenk technique; Inert atmosphere;	58%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 30913-87-2
4-(4-bromophenyl)-4-oxobutanoic acid ethyl ester

: 4-(4-(1,1-difluoroethyl)phenyl)-4-oxobutanoic acid ethyl ester

Conditions

Conditions	Yield
With dmap; bis(tricyclohexylphosphine)nickel(II) dichloride; 4,4'-diamino-2,2'-bipyridyl; magnesium chloride; zinc In dimethyl sulfoxide at 110℃; for 10h; Schlenk technique;	61%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 58743-79-6
1-bromo-4-(4'-ethylphenyl)benzene

: 4-(1,1-difluoroethyl)-4'-ethyl-1,1'-biphenyl

Conditions

Conditions	Yield
With dmap; bis(tricyclohexylphosphine)nickel(II) dichloride; 4,4'-diamino-2,2'-bipyridyl; magnesium chloride; zinc In dimethyl sulfoxide at 110℃; for 10h; Schlenk technique;	58%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 63619-51-2
4-bromo-4'-pentyloxybiphenyl

: 4-(1,1-difluoroethyl)-4'-(pentyloxy)-1,1'-biphenyl

Conditions

Conditions	Yield
With dmap; bis(tricyclohexylphosphine)nickel(II) dichloride; 4,4'-diamino-2,2'-bipyridyl; magnesium chloride; zinc In dimethyl sulfoxide at 110℃; for 10h; Schlenk technique;	56%

: 918655-03-5
4-(naphthalene-2-yl)phenylboronic acid pinacol ester

: 75-68-3
1-Chloro-1,1-difluoroethane

: 2-(4-(1,1-difluoroethyl)phenyl)naphthalene

Conditions

Conditions	Yield
With dmap; bis(triphenylphosphine)nickel(II) chloride; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 5h; Schlenk technique; Inert atmosphere;	55%
With dmap; trans-[Ni(Cl)2(PPh3)2]; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 5h; Suzuki-Miyaura Coupling;	55%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 5122-95-2
3-Biphenylboronic acid

: 3-(1,1-difluoroethyl)-1,1'-biphenyl

Conditions

Conditions	Yield
With dmap; trans-[Ni(Cl)2(PPh3)2]; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 5h; Suzuki-Miyaura Coupling;	54%
With dmap; bis(triphenylphosphine)nickel(II) chloride; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 5h; Schlenk technique; Inert atmosphere;	49%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 57102-42-8
N-(4-bromophenyl)carbazole

: 9-(4-(1,1-difluoroethyl)phenyl)-9H-carbazole

Conditions

Conditions	Yield
With dmap; bis(tricyclohexylphosphine)nickel(II) dichloride; 4,4'-diamino-2,2'-bipyridyl; magnesium chloride; zinc In dimethyl sulfoxide at 110℃; for 10h; Schlenk technique;	54%

: 158937-25-8
4-(4-n-pentyloxyphenyl)phenylboronic acid

: 75-68-3
1-Chloro-1,1-difluoroethane

: 4-(1,1-difluoroethyl)-4'-(pentyloxy)-1,1'-biphenyl

Conditions

Conditions	Yield
With dmap; trans-[Ni(Cl)2(PPh3)2]; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 5h; Suzuki-Miyaura Coupling;	51%
With dmap; bis(triphenylphosphine)nickel(II) chloride; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 5h; Schlenk technique; Inert atmosphere;	48%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 2051-62-9
4'-biphenyl chloride

: 4-(1,1-difluoroethyl)-1,1’-biphenyl

Conditions

Conditions	Yield
With dmap; bis(tricyclohexylphosphine)nickel(II) dichloride; 4,4'-diamino-2,2'-bipyridyl; magnesium chloride; zinc In dimethyl sulfoxide at 110℃; for 10h; Schlenk technique;	49%

: 34784-05-9
6-bromo-isoquinoline

: 75-68-3
1-Chloro-1,1-difluoroethane

: 6-(1,1-difluoroethyl)isoquinoline

Conditions

Conditions	Yield
With dmap; bis(tricyclohexylphosphine)nickel(II) dichloride; 4,4'-diamino-2,2'-bipyridyl; magnesium chloride; zinc In dimethyl sulfoxide at 110℃; for 10h; Schlenk technique;	46%

: 5332-25-2
6-bromoquinoline

: 75-68-3
1-Chloro-1,1-difluoroethane

: 6-(1,1-difluoroethyl)quinoline

Conditions

Conditions	Yield
With dmap; bis(tricyclohexylphosphine)nickel(II) dichloride; 4,4'-diamino-2,2'-bipyridyl; magnesium chloride; zinc In dimethyl sulfoxide at 110℃; for 10h; Schlenk technique;	44%

: 22439-61-8
2-bromodibenzothiophene

: 75-68-3
1-Chloro-1,1-difluoroethane

: 2-(1,1-difluoroethyl)dibenzo[b,d]thiophene

Conditions

Conditions	Yield
With dmap; bis(tricyclohexylphosphine)nickel(II) dichloride; 4,4'-diamino-2,2'-bipyridyl; magnesium chloride; zinc In dimethyl sulfoxide at 110℃; for 10h; Schlenk technique;	43%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 2113-57-7
3-bromobiphenyl

: 3-(1,1-difluoroethyl)-1,1'-biphenyl

Conditions

Conditions	Yield
With dmap; bis(tricyclohexylphosphine)nickel(II) dichloride; 4,4'-diamino-2,2'-bipyridyl; magnesium chloride; zinc In dimethyl sulfoxide at 110℃; for 10h; Schlenk technique;	40%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 128388-54-5
3,5-diphenylphenylboronic acid

: 5'-(1,1-difluoroethyl)-1,1':3',1"-terphenyl

Conditions

Conditions	Yield
With dmap; trans-[Ni(Cl)2(PPh3)2]; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 5h; Suzuki-Miyaura Coupling;	39%
With dmap; bis(triphenylphosphine)nickel(II) chloride; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 5h; Schlenk technique; Inert atmosphere;	34%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 103068-20-8
1-bromo-3,5-diphenylbenzene

: 5'-(1,1-difluoroethyl)-1,1':3',1"-terphenyl

Conditions

Conditions	Yield
With dmap; bis(tricyclohexylphosphine)nickel(II) dichloride; 4,4'-diamino-2,2'-bipyridyl; magnesium chloride; zinc In dimethyl sulfoxide at 110℃; for 10h; Schlenk technique;	39%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 186498-02-2
4-(4-morpholinyl)phenylboronic acid

: 4-(4-(1,1-difluoroethyl)phenyl)morpholine

Conditions

Conditions	Yield
With dmap; trans-[Ni(Cl)2(PPh3)2]; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 5h; Suzuki-Miyaura Coupling;	28%
With dmap; bis(triphenylphosphine)nickel(II) chloride; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 5h; Schlenk technique; Inert atmosphere;	22%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 881913-20-8
(3-(naphthalen-1-yl)phenyl)boronic acid

: 1-(3-(1,1-difluoroethyl)phenyl)naphthalene

Conditions

Conditions	Yield
With dmap; bis(triphenylphosphine)nickel(II) chloride; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 5h; Schlenk technique; Inert atmosphere;	26%

: 870774-25-7
(4-(naphthalen-1-yl)phenyl)boronic acid

: 75-68-3
1-Chloro-1,1-difluoroethane

: C18H14F2

Conditions

Conditions	Yield
With dmap; trans-[Ni(Cl)2(PPh3)2]; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 5h; Suzuki-Miyaura Coupling;	26%

: 75-68-3
1-Chloro-1,1-difluoroethane

: 952514-79-3
(4-(1-phenyl-1H-benzo [d]imidazole-2-yl) phenyl)boronic acid

: 2-(4-(1,1-difluoroethyl)phenyl)-1-phenyl-1H-benzo[d]imidazole

Conditions

Conditions	Yield
With dmap; bis(triphenylphosphine)nickel(II) chloride; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 5h; Schlenk technique; Inert atmosphere;	16%
With dmap; trans-[Ni(Cl)2(PPh3)2]; 4,4'-Dimethoxy-2,2'-bipyridin; potassium carbonate In 1,2-dimethoxyethane at 110℃; for 5h; Suzuki-Miyaura Coupling;	16%

1-Chloro-1,1-difluoroethane Consensus Reports

Reported in EPA TSCA Inventory.

1-Chloro-1,1-difluoroethane Standards and Recommendations

DFG MAK: 1000 ppm (4200 mg/m³)
DOT Classification: 2.1; Label: Flammable Gas

1-Chloro-1,1-difluoroethane Specification

The 1-Chloro-1,1-difluoroethane , with its chemical register number75-68-3, is also called as 1,1,1-chlorodifluoroethane ; 1-Chlor-1,1-difluorethan ; 1-chloro-1,1-difluoro ; 1-chloro-1,1-difluoro-ethan ; alpha-Chloroethylidene fluoride ; alpha-chloroethylidenefluoride ; CFC 142b;cfc142b .

The physical properties of this chemcial are as followings:(1)ACD/LogP: 1.33 ; (2)ACD/LogD (pH 5.5): 1.33 ; (3)ACD/LogD (pH 7.4): 1.33 ; (4)ACD/BCF (pH 5.5): 6 ; (5)ACD/BCF (pH 7.4): 6 ; (6)ACD/KOC (pH 5.5): 125.52 ; (7)ACD/KOC (pH 7.4): 125.52 ; (8)Index of Refraction: 1.316 ; (9)Molar Refractivity: 16.45 cm³ ; (10)Molar Volume: 83.8 cm³; (11)Polarizability: 6.52 ×10^-24cm³ ; (12)Surface Tension: 14.7 dyne/cm ; (13)Density: 1.198 g/cm³ ; (14)Enthalpy of Vaporization: 23.14 kJ/mol ; (15)Vapour Pressure: 2470 mmHg at 25°C.

Being a kind of extremely flammable chemical, it has an extremely low flash point and boiling point, and gases that catch fire in contact with air. Besides, it is dangerous for the environment, for it may present an immediate or delayed danger to one or more components of the environment and it will be dangerous for the ozone layer. What's more, this chemical is irritant and will cause inflammation to the skin or other mucous membranes. So while dealing with this chemical, we should be very cautious. Wear eye/face protection and then refer to manufacturer/supplier for information on recovery/recycling.

This is a kind of transparent colorless liquid with no odour. And it is stable and incompatible with strong oxidizing agents, metals - use brass regulators, steel cylinders for storage. As for its usage, it is widely used in many ways, such as being the working medium for the air cooler in hot environment and as reaction medium for heat pump'working medium and temperature control instrument, and also being the intermediate for refrigerating fluid and rocket propellant. Besides, its product categories are including the followings: Industrial/Fine Chemicals;HCFC;refrigerants;Organics.

Additionally, you could convert the following data information into the molecular structure:
SMILES:ClC(F)(F)C
InChI:InChI=1/C2H3ClF2/c1-2(3,4)5/h1H3
InChIKey:BHNZEZWIUMJCGF-UHFFFAOYAO

Below are the toxicity information of this chemical:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LC50	inhalation	1758gm/m3/2H (1758000mg/m3)		"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 53, 1982.
rat	LC50	inhalation	2050gm/m3/4H (2050000mg/m3)		"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 53, 1982.

Product Name

1-Chloro-1,1-difluoroethane

Synthetic route

1-Chloro-1,1-difluoroethane Consensus Reports

1-Chloro-1,1-difluoroethane Standards and Recommendations

1-Chloro-1,1-difluoroethane Specification

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