2'-Hydroxy-5'-methoxyacetophenone supplier

Name
2'-Hydroxy-5'-methoxyacetophenone
EINECS 211-882-3
CAS No. 705-15-7
Article Data52
CAS DataBase
Density 1.158 g/cm³
Solubility
Melting Point 52 °C(lit.)
Formula C₉H₁₀O₃
Boiling Point 272 °C at 760 mmHg
Molecular Weight 166.177
Flash Point 107.6 °C
Transport Information
Appearance yellow crystalline powder
Safety 26-36/37/39-22
Risk Codes 41-36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Acetophenone,2'-hydroxy-5'-methoxy- (7CI,8CI);1-(2-hydroxy-5-methoxyphenyl)ethanone;2-Acetyl-4-methoxyphenol;2-Hydroxy-5-Methyloxyacetophenone;2-Hydroxy-5-methoxyacetophenone;2'-Hydroxy-5'-methoxyacetophenone;5-Methoxy-2-hydroxyacetophenone;NSC 338218;
PSA 46.53000
LogP 1.60340

Synthetic route

: 1201-38-3
2',5'-dimethoxyacetophenone

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

Conditions

Conditions	Yield
With aluminum (III) chloride In dichloromethane at -5 - 25℃;	95%
With aluminium(III) iodide; N,N-dimethyl-formamide dimethyl acetal In acetonitrile at 80℃; for 18h;	85%
With aluminium(III) iodide; N,N-dimethyl-formamide dimethyl acetal In acetonitrile at 80℃; for 18h;	85%
With aluminium trichloride In acetonitrile for 6h; Thermodynamic data; Heating; ΔG(excit.), ΔH(excit.), ΔS(excit.); conversion vs. reaction time;

: 115-10-6
Dimethyl ether

: 1205-91-0
benzene-1,4-diyl diacetate

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

Conditions

Conditions	Yield
With boron trifluoride for 1h; Fries rearrangement; Heating;	90%

: 1200-06-2
4-methoxyphenyl acetate

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

Conditions

Conditions	Yield
With potassium carbonate In hexane at 25℃; for 12h; Irradiation;	89%
With aluminum (III) chloride at 150℃; for 3.5h;	75%
for 0.116667h; Rearrangement; microwave irradiation;	62%

: 150-76-5
4-methoxy-phenol

: 75-36-5
acetyl chloride

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

Conditions

Conditions	Yield
With 1-carboxymethyl-3-methylimidazolium tetrachloroferrate In neat (no solvent) at 100℃; for 1.5h; Friedel-Crafts Acylation; Green chemistry; regioselective reaction;	87%

: 490-78-8
2,5-Dihydroxyacetophenone

: 74-88-4
methyl iodide

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

Conditions

Conditions	Yield
In acetone	83%
With potassium carbonate In acetone for 6h; Heating;	64%
With potassium carbonate; acetone

: 75-77-4
chloro-trimethyl-silane

: 85630-32-6
N,N-diethyl-2-hydroxy-5-methoxybenzamide

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

Conditions

Conditions	Yield
With lithium diisopropyl amide In tetrahydrofuran at 0 - 20℃; for 0.5h; Inert atmosphere;	81%

: 64-19-7
acetic acid

: 150-78-7
1,4-dimethoxybezene

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

Conditions

Conditions	Yield
With boron trifluoride

: 64-19-7
acetic acid

: 150-78-7
1,4-dimethoxybezene

A: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

B: 1201-38-3
2',5'-dimethoxyacetophenone

Conditions

Conditions	Yield
With boron trifluoride

...Expand

: 75-36-5
acetyl chloride

: 150-78-7
1,4-dimethoxybezene

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

Conditions

Conditions	Yield
With aluminium trichloride; diethyl ether
With carbon disulfide; aluminium trichloride Erwaermen des Reaktionsprodukts mit AlCl3 in Aether;
With aluminium trichloride In dichloromethane

: 7446-70-0
aluminium trichloride

: 60-29-7
diethyl ether

: 75-36-5
acetyl chloride

: 150-78-7
1,4-dimethoxybezene

A: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

B: 1201-38-3
2',5'-dimethoxyacetophenone

...Expand

: 75-36-5
acetyl chloride

: 150-78-7
1,4-dimethoxybezene

A: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

B quinoacetophenonedimethyl ether: quinoacetophenonedimethyl ether

Conditions

Conditions	Yield
With carbon disulfide; aluminium trichloride

...Expand

: 77-78-1
dimethyl sulfate

quinoacetophenone: quinoacetophenone

A: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

B quinoacetophenonedimethyl ether: quinoacetophenonedimethyl ether

Conditions

Conditions	Yield
With sodium hydroxide

...Expand

: 7446-70-0
aluminium trichloride

: 1200-06-2
4-methoxyphenyl acetate

A: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

B: 490-78-8
2,5-Dihydroxyacetophenone

Conditions

Conditions	Yield
at 65℃;

...Expand

: 108-24-7
acetic anhydride

: 123-31-9
hydroquinone

: 77-78-1
dimethyl sulfate

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

Conditions

Conditions	Yield
Stage #1: acetic anhydride; hydroquinone With sulfuric acid Stage #2: With aluminium trichloride at 160℃; Stage #3: dimethyl sulfate With potassium carbonate

...Expand

: 490-78-8
2,5-Dihydroxyacetophenone

MeX: MeX

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

Conditions

Conditions	Yield
With potassium carbonate; sodium iodide In N,N-dimethyl-formamide at 60℃; for 24h;

: 586-37-8
1-(3-Methoxyphenyl)ethanone

A: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

B: 5451-83-2
acetic acid 3-methoxyphenyl ester

C: 703-98-0
1-(2-hydroxy-3-methoxyphenyl)ethanone

Conditions

Conditions	Yield
With toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid In acetonitrile at 80℃; for 2h; Baeyer-Villiger oxidation;	A 2 % Chromat. B 9 % Chromat. C 4 % Chromat.

...Expand

: 123-31-9
hydroquinone

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: ZnCl2 2: aq. NaOH solution View Scheme

: 150-76-5
4-methoxy-phenol

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: pyridine / 3.5 h / 100 °C 2: aluminum (III) chloride / 3.5 h / 150 °C View Scheme
Multi-step reaction with 3 steps 1: potassium carbonate / acetonitrile / 12 h / 20 °C / Inert atmosphere; Reflux 2: lithium diisopropyl amide / tetrahydrofuran / -78 - 20 °C / Inert atmosphere 3: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / 0 - 20 °C / Inert atmosphere View Scheme
Multi-step reaction with 2 steps 1: sulfuric acid 2: aluminum (III) chloride / 120 - 130 °C View Scheme
Multi-step reaction with 2 steps 1: 90 °C 2: aluminum (III) chloride / 5 h / 120 °C View Scheme

: 85630-18-8
N,N-diethyl-O-(4-methoxyphenyl)carbamate

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: lithium diisopropyl amide / tetrahydrofuran / -78 - 20 °C / Inert atmosphere 2: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / 0 - 20 °C / Inert atmosphere View Scheme

: 490-78-8
2,5-Dihydroxyacetophenone

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

Conditions

Conditions	Yield
With methyl iodide In acetone at 20℃; for 12h;

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 75-16-1
methylmagnesium bromide

: 15000-00-7
2-(1-hydroxy-1-methyl-ethyl)-4-methoxy-phenol

Conditions

Conditions	Yield
Stage #1: 1-(2-hydroxy-5-methoxyphenyl)ethan-1-one; methylmagnesium bromide In tetrahydrofuran at 0 - 20℃; for 16.5h; Stage #2: With ammonium chloride In tetrahydrofuran; water	100%
In tetrahydrofuran at 0 - 20℃; for 16.5h;	100%
In tetrahydrofuran at 0 - 20℃; for 16.5h;	100%
In tetrahydrofuran at 0 - 20℃; for 16.5h;	100%

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 1247949-38-7
2-(1-iminoethyl)-4-methoxyphenol

Conditions

Conditions	Yield
With ammonia In methanol at 20℃; Cooling with ice;	100%

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 3392-97-0
2,6-dimethoxybenzaldehyde

: (2E)-3-(2,6-dimethoxyphenyl)-1-(2-hydroxy-5-methoxyphenyl)prop-2-en-1-one

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; water at 20℃; Aldol Condensation;	100%

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 108-24-7
acetic anhydride

: 72229-47-1
2'-acetoxy-5'-methoxyacetophenone

Conditions

Conditions	Yield
In pyridine for 0.5h; Heating;	99%

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 100-39-0
benzyl bromide

: 65547-82-2
2'-benzyloxy-5'-methoxyacetophenone

Conditions

Conditions	Yield
With potassium carbonate In acetone for 72h; Heating;	99%

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 513-35-9
2-methyl-but-2-ene

: 1-(5-methoxy-2,2,3-trimethyl-2,3-dihydrobenzo[2,3-b]furan-7-yl)ethan-1-one

Conditions

Conditions	Yield
With lithium perchlorate; acetic acid In nitromethane Cycloaddition; Electrochemical reaction;	99%
With lithium perchlorate; acetic acid In nitromethane; cyclohexane at 25 - 60℃; Electrochemical reaction;	93%
With lithium perchlorate; acetic acid In nitromethane Electrolysis;	90 %Spectr.
With acetic acid In nitromethane at 20℃; Reagent/catalyst; Electrolysis;

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 95-92-1
oxalic acid diethyl ester

: 52866-24-7
ethyl 6-methoxy-4-oxo-4H-chromene-2-carboxylate

Conditions

Conditions	Yield
With sodium ethanolate In ethanol for 1h; Heating;	98%
With sodium ethanolate In ethanol for 1h; Heating / reflux;	98%
With ethanol; sodium ethanolate Behandeln des Reaktionsgemisches mit wss.-aethanol. Salzsaeure;

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 23997-97-9
(E)-2-hydroxy-5-methoxyacetophenone oxime

Conditions

Conditions	Yield
With pyridine; hydroxylamine hydrochloride In ethanol at 20℃;	98%

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 37113-61-4
1-(3-bromo-2-hydroxy-5-methoxyphenyl)ethan-1-one

Conditions

Conditions	Yield
With bromine; sodium acetate; acetic acid	97%
With bromine; sodium acetate; acetic acid at 20℃; for 48h;	87%
With bromine; sodium acetate In acetic acid at 15 - 25℃; for 16h;	210 g

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 488-43-7
1-Amino-1-deoxy-D-glucitol

: 1-deoxy-1-(2-hydroxy-α-methyl-5-methoxybenzylidene)amino-D-glucitol

Conditions

Conditions	Yield
In methanol; water at 90℃; for 0.333333h;	97%

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 40620-00-6
3-chloro-1-benzofuran-2-carbaldehyde

: 87487-52-3
(E)-3-(3-Chloro-benzofuran-2-yl)-1-(2-hydroxy-5-methoxy-phenyl)-propenone

Conditions

Conditions	Yield
With potassium hydroxide In ethanol; water Ambient temperature;	96%

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 124-63-0
methanesulfonyl chloride

: 72229-67-5
2-acetyl-4-methoxyphenyl methanesulfonate

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 0 - 20℃; for 4h;	96%

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 67-64-1
acetone

: 13229-59-9
6-methoxy-2,2-dimethylchroman-4-one

Conditions

Conditions	Yield
Stage #1: acetone With pyrrolidine; butyric acid In dimethyl sulfoxide for 0.25h; Kabe Chromanone Synthesis; Stage #2: 1-(2-hydroxy-5-methoxyphenyl)ethan-1-one In dimethyl sulfoxide at 20℃; for 1.5h; Kabe Chromanone Synthesis;	95%
With Amberlite IRA 400 basic resin for 0.0833333h; Microwave irradiation; Neat (no solvent);	91%
With pyrrolidine In ethanol for 12h; Inert atmosphere; Reflux;	84.6%
With pyrrolidine In toluene Ambient temperature; a) RT, 3 h, b) reflux, 18 h;	53%
With pyrrolidine In ethanol at 75℃; for 4h; Inert atmosphere; Schlenk technique;

: 75-77-4
chloro-trimethyl-silane

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 158531-80-7
1-<2'-<(trimethylsilyl)oxy>-5'-methoxyphenyl>-1-<(trimethylsilyl)oxy>ethylene

Conditions

Conditions	Yield
With triethylamine; sodium iodide In acetonitrile for 2h; Ambient temperature;	95%

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 358-23-6
trifluoromethylsulfonic anhydride

: 1051384-12-3
2-acetyl-4-methoxylphenyl triflate

Conditions

Conditions	Yield
With pyridine at 0 - 20℃; for 12h;	95%
With triethylamine In dichloromethane at 0 - 20℃; Inert atmosphere;

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 79-37-8
oxalyl dichloride

: 68-12-2, 33513-42-7
N,N-dimethyl-formamide

: 42059-79-0
6-methoxy-4-oxo-4H-chromene-3-carbaldehyde

Conditions

Conditions	Yield
Stage #1: 1-(2-hydroxy-5-methoxyphenyl)ethan-1-one; N,N-dimethyl-formamide In tetrahydrofuran at 0℃; Inert atmosphere; Stage #2: oxalyl dichloride In tetrahydrofuran at 0 - 20℃; for 12h; Inert atmosphere;	95%

...Expand

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 7677-24-9
trimethylsilyl cyanide

: 75-04-7
ethylamine

: 1-(2-hydroxy-5-methoxyphenyl)-1-(ethylamino)ethylcyanide

Conditions

Conditions	Yield
Stage #1: 1-(2-hydroxy-5-methoxyphenyl)ethan-1-one; ethylamine With zinc(II) oxide In neat (no solvent) at 20℃; for 0.166667h; Green chemistry; Stage #2: trimethylsilyl cyanide In neat (no solvent) at 20℃; Green chemistry;	95%

...Expand

: 119-65-3
isoquinoline

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 619-41-0
4-(bromoacetyl)toluene

: [2-(3-methoxyphenyl)pyrrolo[2,1-a]isoquinolin-3-yl](4-methylphenyl)methanone

Conditions

Conditions	Yield
Stage #1: isoquinoline; 4-(bromoacetyl)toluene In water at 80℃; for 0.5h; Green chemistry; Stage #2: 1-(2-hydroxy-5-methoxyphenyl)ethan-1-one With carbonic acid dimethyl ester In water at 80℃; for 3h; Green chemistry;	95%

...Expand

: 119-65-3
isoquinoline

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 2632-13-5
2-Bromo-4'-methoxyacetophenone

: (4-methoxyphenyl)[2-(3-methoxyphenyl)pyrrolo[2,1-a]isoquinolin-3-yl]methanone

Conditions

Conditions	Yield
Stage #1: isoquinoline; 2-Bromo-4'-methoxyacetophenone In water at 80℃; for 0.5h; Green chemistry; Stage #2: 1-(2-hydroxy-5-methoxyphenyl)ethan-1-one With carbonic acid dimethyl ester In water at 80℃; for 3h; Green chemistry;	95%

...Expand

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 123-11-5
4-methoxy-benzaldehyde

: 2284-20-0
4-Methoxyphenyl isothiocyanate

: 616-38-6
carbonic acid dimethyl ester

: 109-77-3
malononitrile

: C29H23N3O6S

Conditions

Conditions	Yield
Stage #1: 1-(2-hydroxy-5-methoxyphenyl)ethan-1-one; carbonic acid dimethyl ester With magnetic Fe3O4 nanoparticles and ZnO nanoparticles on multiwalled carbon nanotubes at 20℃; for 0.333333h; Stage #2: 4-methoxy-benzaldehyde; malononitrile With magnetic Fe3O4 nanoparticles and ZnO nanoparticles on multiwalled carbon nanotubes at 20℃; for 1h; Stage #3: 4-Methoxyphenyl isothiocyanate at 20℃; for 2h;	95%

Yield

Stage #1: 1-(2-hydroxy-5-methoxyphenyl)ethan-1-one; carbonic acid dimethyl ester With magnetic Fe3O4 nanoparticles and ZnO nanoparticles on multiwalled carbon nanotubes at 20℃; for 0.333333h;
Stage #2: 4-methoxy-benzaldehyde; malononitrile With magnetic Fe3O4 nanoparticles and ZnO nanoparticles on multiwalled carbon nanotubes at 20℃; for 1h;
Stage #3: 4-Methoxyphenyl isothiocyanate at 20℃; for 2h;

95%

...Expand

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 403-43-0
4-fluorobenzoyl chloride

: 312607-68-4
1-(4-fluorophenyl)-3-(2-hydroxy-5-methoxyphenyl)propane-1,3-dione

Conditions

Conditions	Yield
Stage #1: 1-(2-hydroxy-5-methoxyphenyl)ethan-1-one With lithium hexamethyldisilazane In tetrahydrofuran; hexane at -78 - 20℃; Inert atmosphere; Stage #2: 4-fluorobenzoyl chloride In tetrahydrofuran; hexane at -78 - 20℃; Inert atmosphere;	94.9%

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 105-58-8
Diethyl carbonate

: 13252-84-1
4-hydroxy-6-methoxycoumarin

Conditions

Conditions	Yield
With sodium hydride In mineral oil at 0 - 100℃;	94%
With sodium hydride In toluene at 0℃; for 4.5h; Reflux;	90%
Stage #1: 1-(2-hydroxy-5-methoxyphenyl)ethan-1-one With sodium hydride In toluene for 0.25h; Inert atmosphere; Cooling with ice; Stage #2: Diethyl carbonate In toluene at 20℃; for 5.5h; Inert atmosphere; Reflux;	82%

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 536-74-3
phenylacetylene

: 2-(4-Phenyl-2-hydroxy-3-butyne-2-yl)-4-methoxyphenol

Conditions

Conditions	Yield
	94%

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 16420-13-6
N,N-Dimethylthiocarbamoyl chloride

: 1239890-31-3
O-2-acetyl-4-methoxyphenyl N,N-dimethylcarbamothioate

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane In N,N-dimethyl-formamide at 50℃; for 5h; Inert atmosphere;	94%

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 1707-03-5
diphenyl-phosphinic acid

: O-2-acetyl-4-methoxyphenyl diphenylphosphinate

Conditions

Conditions	Yield
With N,N-dimethyl-aniline; 1,1'-carbonyldiimidazole In acetonitrile at 20℃; for 12h; Inert atmosphere;	93%

: 705-15-7
1-(2-hydroxy-5-methoxyphenyl)ethan-1-one

: 105-36-2
ethyl bromoacetate

: 33038-04-9
ethyl 2-(2-acetyl-4-methoxyphenoxy)acetate

Conditions

Conditions	Yield
With potassium carbonate In acetone	92%
With potassium carbonate In butanone for 10h; Heating / reflux;	40%
With potassium carbonate; acetone

2'-Hydroxy-5'-methoxyacetophenone Specification

The Ethanone,1-(2-hydroxy-5-methoxyphenyl)-, with CAS registry number 705-15-7, belongs to the following product categories: (1)Aromatic Acetophenones & Derivatives (substituted); (2)C9; (3)Carbonyl Compounds; (4)Ketones. It has the systematic name of 1-(2-hydroxy-5-methoxyphenyl)ethanone. This chemical is a kind of yellow crystalline powder. And it should be stored in cool, dry place.

Physical properties of Ethanone,1-(2-hydroxy-5-methoxyphenyl)-: (1)ACD/LogP: 2.05; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.05; (4)ACD/LogD (pH 7.4): 2.05; (5)ACD/BCF (pH 5.5): 21.34; (6)ACD/BCF (pH 7.4): 21.33; (7)ACD/KOC (pH 5.5): 311.26; (8)ACD/KOC (pH 7.4): 311.08; (9)#H bond acceptors: 3; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 35.53 Å²; (13)Index of Refraction: 1.537; (14)Molar Refractivity: 44.84 cm³; (15)Molar Volume: 143.3 cm³; (16)Polarizability: 17.77×10^-24cm³; (17)Surface Tension: 41.5 dyne/cm; (18)Enthalpy of Vaporization: 53.08 kJ/mol; (19)Vapour Pressure: 0.00374 mmHg at 25°C.

Preparation: this chemical can be prepared by 1-acetoxy-4-methoxy-benzene. This reaction will need reagent AlCl₃.

Uses of Ethanone,1-(2-hydroxy-5-methoxyphenyl)-: it can be used to produce 1-(2-hydroxy-5-methoxy-3-nitro-phenyl)-ethanone. This reaction will need reagents acetic acid, acetic acid anhydride and HNO₃.

When you are using this chemical, please be cautious about it as the following:
The Trimesic acid irritates to eyes, respiratory system and skin. And this chemical has risk of serious damage to the eyes. When use it, do not breathe dust and wear suitable protective clothing, gloves and eye/face protection. If contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(c1cc(OC)ccc1O)C
(2)InChI: InChI=1/C9H10O3/c1-6(10)8-5-7(12-2)3-4-9(8)11/h3-5,11H,1-2H3
(3)InChIKey: MLIBGOFSXXWRIY-UHFFFAOYAB
(4)Std. InChI: InChI=1S/C9H10O3/c1-6(10)8-5-7(12-2)3-4-9(8)11/h3-5,11H,1-2H3
(5)Std. InChIKey: MLIBGOFSXXWRIY-UHFFFAOYSA-N

Product Name

2'-Hydroxy-5'-methoxyacetophenone

Synthetic route

2'-Hydroxy-5'-methoxyacetophenone Specification

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