2-Acetylfuran supplier | CasNO.1192-62-7

Name
2-Acetylfuran
EINECS 214-757-1
CAS No. 1192-62-7
Article Data127
CAS DataBase
Density 1.098 g/mL at 25 °C
Solubility slightly soluble
Melting Point 26-28 °C
Formula C₆H₆O₂
Boiling Point 183.4 °C at 760 mmHg
Molecular Weight 110.112
Flash Point 160 °F
Transport Information UN 2811 6.1/PG 2
Appearance Colorless to light yellow liquid
Safety 26-36/37/39-45-39-38-28A
Risk Codes 20/21-25-41-36/37-23/25
Molecular Structure
Hazard Symbols T
Synonyms 1-(2-furyl)ethanone;Ketone, 2-furyl methyl;Methyl 2-furyl ketone;ethanone, 1-(2-furanyl)-;2-Furyl methyl ketone;Ethanone, 1- (2-furanyl)-;Acetylfuran;2-Acetyl Furan, Natural;2-Acetylfuran , Natural;
PSA 30.21000
LogP 1.48220

Synthetic route

: 110-00-9
furan

: 108-24-7
acetic anhydride

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With indium(III) triflate; lithium perchlorate In nitromethane at 20℃;	99%
With scandium tris(trifluoromethanesulfonate) In acetonitrile for 0.25h; Friedel-Crafts Acylation; Inert atmosphere; Microwave irradiation; Heating; Green chemistry;	99%
With nano-sulfated titania at 50℃; for 40h; Friedel Crafts acylation; neat (no solvent);	95%

: 1487-18-9
(furan-2-yl)ethylene

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With methanesulfonic acid; oxygen; palladium diacetate; [(NH4)5H6PMo4V7.8O40]*xH2O; sodium chloride In methanol; water at 20℃; for 3.5h;	98.2%
With tert.-butylhydroperoxide; C21H19N5Pd(2+)*2BF4(1-) In decane; acetonitrile at 45℃; for 12h; Wacker Oxidation;	90%
With dihydrogen peroxide In water; acetonitrile at 55℃; for 12h; Wacker Oxidation;	80%

: 110-00-9
furan

: 64-19-7
acetic acid

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With methanesulfonic acid; pyrographite at 0 - 10℃; for 0.333333h; Friedel-Crafts acylation;	98%
With pyrographite; toluene-4-sulfonic acid at 20℃; for 0.5h; Friedel-Crafts reaction;	97%
With trifluoroacetic anhydride; Duolite ES 467 H+ phosphonic resin In nitromethane at 25℃; for 0.5h;	95%

: 4208-64-4
1-(2-furyl)ethanol

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With nickel(II) triflate; cyclohexanone; 1,2-bis-(dicyclohexylphosphino)ethane In toluene at 110℃; for 12h; Schlenk technique;	98%
With oxygen; sodium hydride In tetrahydrofuran at 0 - 20℃; for 6h;	97%
With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium tert-butylate; copper(I) triflate; 5-[(2S)-pyrrolidine-2-yl]-1H-tetrazole In N,N-dimethyl-formamide at 25℃; for 0.5h; Catalytic behavior;	97%

: 1450-49-3
(E)-1-(furan-2-yl)ethanone oxime

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With manganese triacetate In benzene for 2h; Heating;	94%

: 110-00-9
furan

: 108-24-7
acetic anhydride

: 64-19-7
acetic acid

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With zinc trifluoromethanesulfonate at 25 - 100℃; for 3h; Reagent/catalyst; Temperature;	94%

...Expand

: 1450-48-2
(Z)-1-(furan-2-yl)ethanone oxime

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With manganese triacetate In benzene for 2h; Heating;	93%

: 488-93-7
3-Furoic acid

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With hydrogenchloride; methyllithium	92%

: 624-65-7
2-propynyl chloride

: 5007-50-1
1-(2-furyl)ethanone oxime

A: 1192-62-7
1-(2-furyl)-1-ethanone

B: 1-furan-2-yl-ethanone O-prop-2-ynyl-oxime

Conditions

Conditions	Yield
With potassium hydroxide In dimethyl sulfoxide at 20 - 35℃; for 2.5h; Etherification; Alkylation; Hydrolysis;	A 12.1% B 87%

...Expand

: 110-00-9
furan

: 75-36-5
acetyl chloride

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With [BPy][BF4]; ytterbium(III) triflate at 50℃; for 3h; Friedel-Crafts acylation;	87%
With zinc trifluoromethanesulfonate In nitromethane at 20℃; for 4h; Friedel-Crafts acylation;	85%

: 2-(1-chloroethyl)furan

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With 4Na(1+)6H(1+)NiMo6O24(10-)=Na4H6NiMo6O24; oxygen In water; acetonitrile at 20℃; under 760.051 Torr; for 12h; Irradiation;	86%
With (NH4)4[ZnMo6O18(OH)6]; oxygen In water; acetonitrile at 60℃; under 760.051 Torr; for 12h;	85%

: 2-(2-methyl[1,3]dithiolan-2-yl)furan

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With tert.-butylhydroperoxide In methanol; water Heating;	85%

: 593-71-5
Chloroiodomethane

Cr-carbene complex: Cr-carbene complex

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With methyllithium; lithium bromide In tetrahydrofuran; diethyl ether at -78℃; for 0.25h;	83%

: 3208-16-0
2-ethylfuran

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With FeH6Mo6O24(3-)3H3N3H(1+)*7H2O; tetrabutylammomium bromide; dihydrogen peroxide In 1,4-dioxane at 70℃; for 24h;	83%
With tert.-butylhydroperoxide; phosphomolybdic acid; copper diacetate In water; acetonitrile at 90℃;	66%
With tert.-butylhydroperoxide; phosphomolybdic acid; copper(II) acetate monohydrate In water; acetonitrile at 90℃; for 10h; Sealed tube;	66%
With tert.-butylhydroperoxide In water; acetonitrile at 25℃; for 30h; UV-irradiation;	65%
With oxygen; Langlois reagent In acetonitrile at 25℃; under 760.051 Torr; for 12h; Irradiation; Green chemistry;	51 %Chromat.

: 18649-64-4
2-ethynylfuran

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With Perfluorooctanesulfonic acid; C8AgF17O3S*H2O In water at 100℃; for 8h; Darkness; regioselective reaction;	80%
With silver tetrafluoroborate; water In acetic acid at 110℃; for 10h; regioselective reaction;	76%

: 62889-08-1
1-(2-furyl)-1-(trimethylsilyloxy)ethylene

A: 1192-62-7
1-(2-furyl)-1-ethanone

B: 55984-17-3
2-chloroacetylfuran

C: 140613-99-6
2,2‐dichloro‐1‐(furan‐2‐yl)ethan‐1‐one

D: 2-chloroacetyl-5-chlorofuran

Conditions

Conditions	Yield
With tert-butylhypochlorite; silica gel In hexane at 0℃; for 1h;	A 10 % Chromat. B 77% C 10 % Chromat. D 1 % Chromat.

...Expand

: 51583-40-5
2-(trimethylstannyl)furan

: 75-36-5
acetyl chloride

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
trans benzyl(chloro)bis(triphenylphosphine)palladium(II) In benzene for 0.5h; Ambient temperature;	70%

: 110-00-9
furan

: 141-82-2
malonic acid

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With PPA at 60 - 80℃; for 2h; Acylation; Friedel-Crafts acylation;	70%

: 3375-31-3
palladium diacetate

: 81-07-2
saccharin

: 607-01-2
ethyl-diphenyl-phosphane

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
Stage #1: palladium diacetate; saccharin In water; acetonitrile at 20℃; for 0.5h; Stage #2: ethyl-diphenyl-phosphane In methanol; water; acetonitrile Reflux;	66%

...Expand

: 76007-17-5
2-N-methylanilinoacetylfuran

A: 1192-62-7
1-(2-furyl)-1-ethanone

B: 2513-64-6
1,3-diphenylimidazolidine

C: 76007-24-4
3-(2-furyl)-1-phenylazetidin-3-ol

Conditions

Conditions	Yield
In diethyl ether for 3h; Irradiation;	A 13% B 9% C 45%

...Expand

: 136590-93-7
(1-(furan-2-yl)ethoxy)trimethylsilane

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In dichloromethane; acetonitrile for 3h; Irradiation;	43%

: 110-00-9
furan

: 141-78-6
ethyl acetate

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With trifluorormethanesulfonic acid at 80℃; Inert atmosphere;	39%

: 33647-67-5
1-(2,5-dimethoxy-2,5-dihydrofuran-2-yl)ethanol from 2-Acetylfuran

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
at 130℃; for 2h;	26%

: 186581-53-3, 908094-01-9
diazomethane

: 98-01-1
furfural

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With diethyl ether

: 917-64-6
methyl magnesium iodide

: 72667-24-4
Brenzschleimsaeurenitril

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With diethyl ether

: 615-09-8
ethyl 3-(2-furyl)-3-oxopropanoate

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With sulfuric acid

: 4208-64-4
1-(2-furyl)ethanol

A: 1192-62-7
1-(2-furyl)-1-ethanone

B: 27948-61-4
(R)-(+)-1-(2-furyl)ethanol

Conditions

Conditions	Yield
With baker's yeast; pH 5 phosphate buffer In 1,2-dimethoxyethane at 32℃; for 192h; kinetic resolution of other 1-substituted ethanols with Baker's yeast; other solvents, time;	A 79 % Chromat. B 21 % Chromat.
In 1,2-dimethoxyethane at 32℃; for 192h; Baker's yeast, pH 5 phosphate buffer;	A 79 % Chromat. B 21 % Chromat.
In 1,2-dimethoxyethane at 32℃; for 168h; Baker's yeast, pH 5 phosphate buffer;	A 68 % Chromat. B 32 % Chromat.

: 32488-17-8
N,N-diethyl furan 2-carboxamide

: 917-54-4
methyllithium

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
With lanthanum(lll) triflate 1.) THF, -78 deg C then up to 0 deg C, 2.) -78 up to 0 deg C, 30 min; Yield given. Multistep reaction;

: 99940-18-8
2-(furan-2-yl)pent-4-en-2-ol

: 1192-62-7
1-(2-furyl)-1-ethanone

Conditions

Conditions	Yield
at 500℃; Product distribution; flash thermolysis;

: 1192-62-7
1-(2-furyl)-1-ethanone

: 383-63-1
ethyl trifluoroacetate,

: 326-90-9
4,4,4-trifluoro-1-(2-furanyl)-1,3-butanedione

Conditions

Conditions	Yield
Stage #1: 1-(2-furyl)-1-ethanone; ethyl trifluoroacetate, With lithium hexamethyldisilazane In tetrahydrofuran at 0 - 20℃; Stage #2: With hydrogenchloride In water; ethyl acetate	100%
With sodium In ethanol at 20℃;	82.6%
With potassium tert-butylate In benzene for 15h; Ambient temperature;	54%

: 1192-62-7
1-(2-furyl)-1-ethanone

: 27948-61-4
(R)-(+)-1-(2-furyl)ethanol

Conditions

Conditions	Yield
With formic acid; C38H40ClN2O2RhS; triethylamine In neat (no solvent) at 24 - 30℃; for 8h; Reagent/catalyst; Inert atmosphere; enantioselective reaction;	100%
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; sodium formate; (R,R)-N-(p-toluenesulfonyl)-1,2-diphenylethylenediamine In water at 40℃; for 1.5h; enantioselective reaction;	99%
With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; sodium formate; 4-methyl-N-((1R,2R)-2-{[(4-methylphenyl)sulfonyl]amino}-1,2-diphenylethyl)benzenesulfonamide In water at 40℃; for 1.5h; enantioselective reaction;	99%

: 110-86-1
pyridine

: 1192-62-7
1-(2-furyl)-1-ethanone

: 53676-94-1
1-(2-furan-2-yl-2-oxo-ethyl)-pyridinium iodide

Conditions

Conditions	Yield
With iodine	100%
With iodine at 140℃; for 3h;	100%
With iodine at 140℃; for 3h;	100%

: 1192-62-7
1-(2-furyl)-1-ethanone

: 5007-50-1
1-(2-furyl)ethanone oxime

Conditions

Conditions	Yield
With hydroxylamine hydrochloride; sodium acetate In ethanol; water Reflux;	100%
With hydroxylamine hydrochloride; sodium acetate In ethanol; water Heating;
With hydroxylamine hydrochloride; sodium acetate In ethanol; water Reflux;

: 1192-62-7
1-(2-furyl)-1-ethanone

: 936-02-7
2-Hydroxybenzoylhydrazine

: 1206732-62-8
(E)-N'-(1-(furan-2-yl)ethylidene)-2-hydroxybenzohydrazide

Conditions

Conditions	Yield
at 194℃; under 4650.47 Torr; for 0.0416667h; Microwave irradiation; neat (no solvent);	100%

: 1192-62-7
1-(2-furyl)-1-ethanone

: 459-57-4
4-fluorobenzaldehyde

: (E)-3-(4-fluorophenyl)-1-(furan-2-yl)-2-propen-1-one

Conditions

Conditions	Yield
With sodium hydroxide at 20℃; for 24h;	100%
With sodium hydroxide In methanol; water at 15 - 20℃; for 15h; Claisen-Schmidt Condensation;	90%
With lithium hydroxide monohydrate In ethanol at 40℃; for 7h; Claisen-Schmidt Condensation;	15%
With sodium hydroxide In ethanol at 25℃; for 3h;
With potassium hydroxide In ethanol at 20℃;

: 1192-62-7
1-(2-furyl)-1-ethanone

: 95-92-1
oxalic acid diethyl ester

: 36983-35-4
ethyl 4-(furan-2-yl)-2,4-dioxobutyrate

Conditions

Conditions	Yield
	99%
With potassium tert-butylate In tetrahydrofuran; 1,2-dimethoxyethane at 0 - 20℃; for 1h;	88%
With potassium tert-butylate In tetrahydrofuran; 1,2-dimethoxyethane for 3h; Knoevenagel Condensation;	70%

: 1192-62-7
1-(2-furyl)-1-ethanone

: 100-52-7
benzaldehyde

: 3988-74-7, 42811-81-4, 69656-34-4
1-(2-furyl)-3-phenylpropen-1-one

Conditions

Conditions	Yield
With potassium fluoride modified clay In methanol at 20℃; for 0.333333h; Catalytic behavior; Solvent; Claisen-Schmidt Condensation;	99%
With potassium hydroxide In water at 20℃; for 4h; Claisen-Schmidt Condensation;	87%
With sodium hydroxide In ethanol; water at 20℃;	87%

: 1192-62-7
1-(2-furyl)-1-ethanone

: 4208-64-4
1-(2-furyl)ethanol

Conditions

Conditions	Yield
With ethanol; (ethylenebis(bicyclohexylphosphane))Ni(cis,cis-1,5-cyclooctadiene) In neat (no solvent) at 130℃; for 36h; Catalytic behavior;	99%
With sodium tetrahydroborate In methanol at 0℃;	98%
Stage #1: 1-(2-furyl)-1-ethanone With n-butyllithium; 1-(2-hydroxyethyl)-3-methyl-1H-imidazol-3-ium trifluoromethanesulfonate; iron(II) acetate In tetrahydrofuran at 65℃; for 1h; Inert atmosphere; Stage #2: With water; sodium hydroxide In tetrahydrofuran; methanol at 20℃; for 2h; Inert atmosphere;	98%

: 1192-62-7
1-(2-furyl)-1-ethanone

: 4208-64-4, 27948-61-4, 106565-48-4, 112653-32-4
(S)-1-(2-furanyl)ethanol

Conditions

Conditions	Yield
diethylzinc; (+)-N,N'-Bis<(R)-1-phenylethyl>-1,2-ethylendiamin	99%
With formic acid; [RuCl2(hexamethylbenzene)]2; (S)-2-piperidinemethanethiol hydrochloride; triethylamine at 30℃; for 24h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%
With formic acid; [RuCl2(hexamethylbenzene)]2; (S)-2-piperidinemethanethiol hydrochloride; triethylamine at 30℃; for 24h; Inert atmosphere; optical yield given as %ee; enantioselective reaction;	99%

: 1192-62-7
1-(2-furyl)-1-ethanone

: 7677-24-9
trimethylsilyl cyanide

: 2-trimethylsilyloxy-2-(furan-2-yl)-propanenitrile

Conditions

Conditions	Yield
With montmorillonite K10 In acetone at 20℃; for 0.833333h; Catalytic behavior; Green chemistry;	99%
With [(3,5-di-tert-Bu,2-OH)-C6H2-CH=N-CH2]2*Ti(O-i-Pr)4; N,N-dimethylaniline N-oxide In dichloromethane at 23℃; for 25h;	94%
phosphotungstic acid at 20℃;	93%

: 1192-62-7
1-(2-furyl)-1-ethanone

: 1120-72-5
2-Methylcyclopentanone

Conditions

Conditions	Yield
With hydrogen In water at 160℃; under 30003 Torr; for 2.5h; Autoclave;	99%
With hydrogen In water at 160℃; under 30003 Torr; for 2.5h; Autoclave;	82%
With water; hydrogen at 160℃; under 30003 Torr; for 4h; Autoclave;

: 1192-62-7
1-(2-furyl)-1-ethanone

: 17049-50-2
n-decyl magnesium bromide

: C16H28O2

Conditions

Conditions	Yield
In diethyl ether at 10 - 20℃; for 1h; Inert atmosphere;	99%

: 1192-62-7
1-(2-furyl)-1-ethanone

: 77287-58-2
2-iodo-5-methoxybenzaldehyde

: (E)-1-(furan-2-yl)-3-(2-iodo-5-methoxyphenyl)prop-2-en-1-one

Conditions

Conditions	Yield
Stage #1: 1-(2-furyl)-1-ethanone With sodium hydroxide In ethanol; water at 0℃; for 0.0833333h; Inert atmosphere; Stage #2: 2-iodo-5-methoxybenzaldehyde In ethanol; water at 10℃; Inert atmosphere;	99%
Stage #1: 1-(2-furyl)-1-ethanone With sodium hydroxide In ethanol; water at 0℃; for 0.0833333h; Stage #2: 2-iodo-5-methoxybenzaldehyde In ethanol; water at 0 - 10℃;	99%

: 1192-62-7
1-(2-furyl)-1-ethanone

: 7175-47-5
4-methylphenyl isocyanide

: C14H13NO2

Conditions

Conditions	Yield
With potassium carbonate; 1,3-bis(mesityl)imidazolium chloride In N,N-dimethyl acetamide at 80℃; for 6h;	99%

: 1192-62-7
1-(2-furyl)-1-ethanone

: 25015-63-8
4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

: 2-(1-(furan-2-yl)ethoxy)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Conditions

Conditions	Yield
With C84H110N10Zn2 In neat (no solvent) at 20℃; for 6h; Sealed tube; Inert atmosphere; Schlenk technique; Glovebox;	99%
at 140℃; for 2.5h;	98%
With C44H60N5PrSi2 In chloroform-d1 at 20℃; for 0.133333h; Inert atmosphere;	90 %Spectr.

: 1192-62-7
1-(2-furyl)-1-ethanone

: 77086-38-5
ketene t-butyldimethylsilyl methyl acetal

: methyl 3-((tert-butyldimethylsilyl)oxy)-3-(furan-2-yl)butanoate

Conditions

Conditions	Yield
Stage #1: 1-(2-furyl)-1-ethanone With bis(trifluoromethanesulfonyl)amide In diethyl ether at -78 - 23℃; Mukaiyama Aldol Addition; Schlenk technique; Inert atmosphere; Stage #2: ketene t-butyldimethylsilyl methyl acetal In diethyl ether at -20℃; for 0.5h; Mukaiyama Aldol Addition; Schlenk technique; Inert atmosphere;	99%

: 1192-62-7
1-(2-furyl)-1-ethanone

: 90-11-9
1-Bromonaphthalene

: 63753-54-8
1-(furan-2-yl)-2-(naphthalen-1-yl)ethan-1-one

Conditions

Conditions	Yield
With methanesulfonic acid(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II); sodium t-butanolate In tetrahydrofuran at 80℃; Inert atmosphere;	99%

: 1192-62-7
1-(2-furyl)-1-ethanone

: 460-00-4
1-Bromo-4-fluorobenzene

: 2-(4-fluorophenyl)-1-(furan-2-yl)ethanone

Conditions

Conditions	Yield
With methanesulfonic acid(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II); sodium t-butanolate In tetrahydrofuran at 80℃; Inert atmosphere;	99%

: 1192-62-7
1-(2-furyl)-1-ethanone

: 99-90-1
para-bromoacetophenone

: 1404372-06-0
2‐acetyl‐5‐(4‐acetylphenyl)furan

Conditions

Conditions	Yield
With potassium acetate; dichloro-[1-(isobutyl)-3-(benzyl)benzimidazole-2-ylidene](pyridine)palladium(II) In N,N-dimethyl acetamide at 150℃; for 2h; Reagent/catalyst; Inert atmosphere; Schlenk technique; regioselective reaction;	99%
With tetrabromo[1,1'-butylene-3,3'-bis(N-2-(diisopropylaminoethyl)benzimidazol-2-ylidene)]dipyridinedipalladium(II); potassium acetate In N,N-dimethyl acetamide at 120℃; for 2h; Reagent/catalyst; Inert atmosphere; Schlenk technique;	92%
With cis-[Pd(saccharine)2(PPhEt2)2]; potassium acetate In N,N-dimethyl acetamide at 120℃; for 2h; Catalytic behavior; Reagent/catalyst; Schlenk technique; Inert atmosphere;	98 %Chromat.
With trans‐dibromo[1‐(2,2‐diethoxyethyl)‐3‐(3,5‐di‐tert‐butylbenzyl)benzimidazole‐2‐ylidene]‐(pyridine)‐palladium(II); potassium acetate In N,N-dimethyl acetamide at 120℃; for 2h; Reagent/catalyst; Schlenk technique;	80 %Chromat.
With potassium acetate; dibromo[1‑(4‑phenoxybutyl)‑3‑(2,3,5,6‑tetramethylbenzyl)imidazolidin‑2‑ylidene](pyridine)palladium(II) In N,N-dimethyl acetamide at 120℃; for 2h; Catalytic behavior; Reagent/catalyst; Inert atmosphere;	97 %Chromat.

: 1192-62-7
1-(2-furyl)-1-ethanone

: 775-12-2
diphenylsilane

: (1-(furan-2-yl)ethoxy)diphenylsilane

Conditions

Conditions	Yield
With C84H110N10Zn2 In neat (no solvent) at 20℃; for 12h; Sealed tube; Inert atmosphere; Schlenk technique; Glovebox;	99%

: 1192-62-7
1-(2-furyl)-1-ethanone

: 100-52-7
benzaldehyde

: 3988-74-7
(E)-1-(furan-2-yl)-3-phenylprop-2-en-1-one

Conditions

Conditions	Yield
With sodium hydroxide at 20℃; for 15h;	98%
With 4 A molecular sieve; NAP-MgO In toluene for 18h; Claisen-Schmidt condensation; Heating;	97%
With fly-ash:H2SO4 Aldol condensation; Microwave irradiation; Neat (no solvent);	95%

: 1192-62-7
1-(2-furyl)-1-ethanone

: trimethylsulfoxonium bromide

: 85575-91-3
2-furyl 2-methyl oxirane

Conditions

Conditions	Yield
With potassium hydroxide In water; acetonitrile at 60℃; for 2h;	98%

: 1192-62-7
1-(2-furyl)-1-ethanone

: 104-88-1
4-chlorobenzaldehyde

: 111042-59-2, 14385-64-9
3-(4-chlorophenyl)-1-(furan-2-yl)prop-2-en-1-one

Conditions

Conditions	Yield
With potassium fluoride modified clay In methanol at 20℃; for 0.333333h; Claisen-Schmidt Condensation;	98%
With sodium hydroxide at 20℃; Claisen-Schmidt condensation; Neat (no solvent); Grinding;	90%
With sodium hydroxide In methanol; water for 2h; Ambient temperature;	88%

: 1192-62-7
1-(2-furyl)-1-ethanone

: 24523-53-3
2-acetylfuran azine

Conditions

Conditions	Yield
With hydrazine hydrate; acetic acid for 40h; Heating;	98%
With hydrazine hydrate; acetic acid In ethanol at 75℃;

: 1192-62-7
1-(2-furyl)-1-ethanone

: 80522-42-5
triisopropylsilyl trifluoromethanesulfonate

: 556025-76-4
[[1-(2-furyl)ethenyl]oxy]tri-isopropylsilane

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃;	98%
With N-ethyl-N,N-diisopropylamine In dichloromethane cooling;

2-Acetylfuran Chemical Properties

Molecular Structure of 2-Acetylfuran (CAS NO.1192-62-7):

IUPAC Name: 1-(Furan-2-yl)ethanone
Canonical SMILES: CC(=O)C1=CC=CO1
InChI: InChI=1S/C6H6O2/c1-5(7)6-3-2-4-8-6/h2-4H,1H3
InChIKey: IEMMBWWQXVXBEU-UHFFFAOYSA-N
Molecular Weight: 110.11064 [g/mol]
Molecular Formula: C₆H₆O₂
XLogP3: 0.5
H-Bond Donor: 0
H-Bond Acceptor: 2
EINECS: 214-757-1
Appearance: Colorless to light yellow liquid
Melting Point: 26-28 °C(lit.)
Boiling Point: 67 °C10 mm Hg(lit.)
Density: 1.098 g/mL at 25 °C(lit.)
FEMA: 3163
Refractive index: n20/D 1.5070(lit.)
Flash Point: 160 °F
storage temp.: 2-8 °C
Classification Code: Mutation data
Product Categories: ACETYLGROUP; Aromatic Ketones (substituted); Furan & Benzofuran; Furans; furnan Flavor

2-Acetylfuran Toxicity Data With Reference

1.	mma-sat 165 nmol/plate	DFSCDX Developments in Food Science. 13 (1986),353.
2.	dnr-bcs 5500 µg/disc	DFSCDX Developments in Food Science. 13 (1986),353.
3.	cyt-ham:ovr 4500 µmol/L	CALEDQ Cancer Letters (Shannon, Ireland). 13 (1981),89.

2-Acetylfuran Consensus Reports

Reported in EPA TSCA Inventory.

2-Acetylfuran Safety Profile

Mutation data reported. A flammable liquid. When heated to decomposition it emits acrid smoke and irritating vapors.
Safety Information of 2-Acetylfuran (CAS NO.1192-62-7):
Hazard Codes: Toxic T
Risk Statements:
25: Toxic if swallowed
41: Risk of serious damage to eyes
20/21: Harmful by inhalation and in contact with skin
23/25: Toxic by inhalation and if swallowed
36/37: Irritating to eyes and respiratory system
Safety Statements:
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
38: In case of insufficient ventilation, wear suitable respiratory equipment
39: Wear eye/face protection
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
36/37/39: Wear suitable protective clothing, gloves and eye/face protection
RIDADR:UN 2811 6.1/PG 2
WGK Germany:3
RTECS:OB3870000
Hazard Note:Toxic

2-Acetylfuran Standards and Recommendations

DOT Classification: 3; Label: Flammable Liquid

2-Acetylfuran Specification

2-Acetylfuran (CAS NO.1192-62-7), its Synonyms are 2-Furyl methyl ketone ; 2-Furyl methyl ketone (natural) ; 2-Furylethanone ; 1-(2-Furanyl)ethanone ; 1-(2-Furyl)ethanone ; Ethanone, 1-(2-furanyl)- ; FEMA No. 3163 ; Furan, 2-acetyl- ; Ketone, 2-furyl methyl ; Methyl 2-furyl ketone ; Acetylfuran .

Product Name

2-Acetylfuran

Synthetic route

2-Acetylfuran Chemical Properties

2-Acetylfuran Toxicity Data With Reference

2-Acetylfuran Consensus Reports

2-Acetylfuran Safety Profile

2-Acetylfuran Standards and Recommendations

2-Acetylfuran Specification

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