Product Name

  • Name

    2-Butanone oxime

  • EINECS 202-496-6
  • CAS No. 96-29-7
  • Article Data55
  • CAS DataBase
  • Density 0.9 g/cm3
  • Solubility 114 g/L (20 °C) in water
  • Melting Point -30 °C
  • Formula C4H9NO
  • Boiling Point 152.5 °C at 760 mmHg
  • Molecular Weight 87.1216
  • Flash Point 60 °C
  • Transport Information UN 1993 3/PG 3
  • Appearance colourless liquid
  • Safety 13-23-26-36/37/39-61-45-36/37-25
  • Risk Codes 21-40-41-43-52/53-48/25
  • Molecular Structure Molecular Structure of 96-29-7 (2-Butanone oxime)
  • Hazard Symbols HarmfulXn, ToxicT
  • Synonyms 2-Butoxime;MEKO;Ethyl methyl ketone oxime;Ethyl methyl ketoxime;Exkin 2;Exkin II;Hiaron M 1;MEK-oxime;Mekor 70;Methyl ethyl ketone oxime;Methyl ethylketoxime;NSC 442;NSC 65465;Troykyd AntiSkin B;Methyl ethyl ketoxime(MEKO);2-Butanone oxime;
  • PSA 32.59000
  • LogP 1.24650

Synthetic route

butanone
78-93-3

butanone

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

Conditions
ConditionsYield
With ammonium sulfate; dihydrogen peroxide; sodium carbonate In water at 60℃; for 5h; Reagent/catalyst; Concentration; Time;99.8%
With tetrabutyl-ammonium chloride; hydroxylamine; sodium hydrogencarbonate In water for 0.166667h; Ambient temperature;96%
With hydroxylamine hydrochloride at 44℃; for 0.05h; Catalytic behavior; Microwave irradiation; Green chemistry;85%
SEC-BUTYLAMINE
33966-50-6

SEC-BUTYLAMINE

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

Conditions
ConditionsYield
With diperoxydodecanedioic acid In N,N-dimethyl-formamide at 20 - 55℃; for 0.333333h;80%
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

Conditions
ConditionsYield
Stage #1: iso-butanol With chromium(VI) oxide; aluminum oxide; tert-butyl alcohol for 0.166667h;
Stage #2: With hydroxylamine hydrochloride for 0.116667h;
79%
2-Methylbutylamine
96-15-1

2-Methylbutylamine

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

Conditions
ConditionsYield
With 3-chloro-benzenecarboperoxoic acid In ethyl acetate at 20℃; for 0.333333h;79%
2-nitrobutane
600-24-8, 116783-22-3

2-nitrobutane

A

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

B

Hexamethyldisiloxane
107-46-0

Hexamethyldisiloxane

C

I2

I2

Conditions
ConditionsYield
With trimethylsilyl iodide In dichloromethane at 25℃; for 16h;A 68%
B n/a
C n/a
2-nitrobutane
600-24-8, 116783-22-3

2-nitrobutane

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

Conditions
ConditionsYield
With n-butyllithium; 1,1,1,2,2,2-hexamethyldisilane In tetrahydrofuran; hexane for 24h; Ambient temperature;61%
2-methyl-1-hydroxy-3-butanone oxime
69125-01-5

2-methyl-1-hydroxy-3-butanone oxime

acetylene
74-86-2

acetylene

A

2,3-dimethyl-1-vinyl-1H-pyrrole
55847-29-5

2,3-dimethyl-1-vinyl-1H-pyrrole

B

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

C

2-(1-methylethenyl)-1-vinylpyrrole
74151-03-4

2-(1-methylethenyl)-1-vinylpyrrole

Conditions
ConditionsYield
With potassium hydroxide In dimethyl sulfoxide at 100℃; under 10640 Torr; for 3h; Product distribution;A 20%
B 3%
C 8%
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

Conditions
ConditionsYield
With acetic acid; zinc
2-Chloro-2-nitrosobutane
681-01-6

2-Chloro-2-nitrosobutane

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

Conditions
ConditionsYield
With methanol beim Bestrahlen mit rotem Licht;
With acetone beim Bestrahlen mit rotem Licht;
2-hydroxy-2-butylhydroxylamine
107093-01-6

2-hydroxy-2-butylhydroxylamine

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

Conditions
ConditionsYield
In methanol; water at 25℃; Rate constant;
hydrogenchloride
7647-01-0

hydrogenchloride

3-hydroxy-3,4-dimethyl-hexane-2,5-dione dioxime

3-hydroxy-3,4-dimethyl-hexane-2,5-dione dioxime

A

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

B

butane-2,3-dione mono-oxime
135636-66-7

butane-2,3-dione mono-oxime

hydroxylamine
7803-49-8

hydroxylamine

butanone
78-93-3

butanone

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

butan-2-one phenylhydrazone
1129-62-0

butan-2-one phenylhydrazone

hydroxylamine hydrochloride

hydroxylamine hydrochloride

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

acetic acid
64-19-7

acetic acid

zinc

zinc

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

butanone
78-93-3

butanone

hydroxylaminemonosulfonate sodium

hydroxylaminemonosulfonate sodium

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

Conditions
ConditionsYield
With acid at 70℃;
methanol
67-56-1

methanol

2-Chloro-2-nitrosobutane
681-01-6

2-Chloro-2-nitrosobutane

A

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

B

butane-2,3-dione mono-oxime
135636-66-7

butane-2,3-dione mono-oxime

C

3.4-dimethyl-hexanol-(3)-dione-(2.5)-dioxime

3.4-dimethyl-hexanol-(3)-dione-(2.5)-dioxime

D

monohydrochloride of 3.4-dimethyl-hexene-(3)-dione-(2.5)-dioxime

monohydrochloride of 3.4-dimethyl-hexene-(3)-dione-(2.5)-dioxime

Conditions
ConditionsYield
mit rotem Licht.Irradiation;
2-Chloro-2-nitrosobutane
681-01-6

2-Chloro-2-nitrosobutane

acetone
67-64-1

acetone

A

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

B

butane-2,3-dione mono-oxime
135636-66-7

butane-2,3-dione mono-oxime

C

3.4-dimethyl-hexanol-(3)-dione-(2.5)-dioxime

3.4-dimethyl-hexanol-(3)-dione-(2.5)-dioxime

D

monohydrochloride of 3.4-dimethyl-hexene-(3)-dione-(2.5)-dioxime

monohydrochloride of 3.4-dimethyl-hexene-(3)-dione-(2.5)-dioxime

Conditions
ConditionsYield
mit rotem Licht.Irradiation;

A

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

B

N-methylpropanamide
1187-58-2

N-methylpropanamide

C

butanone
78-93-3

butanone

Conditions
ConditionsYield
Stage #1: iso-butanol With C19H42N(1+)*2H(1+)*O40PW12(3-); water; dihydrogen peroxide at 80℃; for 6h;
Stage #2: With hydroxyammonium sulfate at 100℃; for 5h; Catalytic behavior; Beckmann Rearrangement; Overall yield = 92.6 %Chromat.;
A 40.1 %Chromat.
B 34.6 %Chromat.
C 25.2 %Chromat.

A

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

B

butanone
78-93-3

butanone

C

N-ethylacetamide
625-50-3

N-ethylacetamide

Conditions
ConditionsYield
Stage #1: iso-butanol With caprolactam; N,N,N-trimethyl-N-(butanesulfonic acid)ammonium hydrogensulfate; 6Na(1+)*O4W(2-)*2H2O at 80℃; Green chemistry;
Stage #2: With hydroxyammonium sulfate at 80℃; for 5h; Green chemistry;
butanone
78-93-3

butanone

A

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

B

N-methylpropanamide
1187-58-2

N-methylpropanamide

Conditions
ConditionsYield
With K2Co4[WZn3(H2O)2][ZnW9O34]2*53H2O; ammonia; dihydrogen peroxide In water at 20℃; for 6h;A 12 %Spectr.
B 88 %Spectr.
butanone
78-93-3

butanone

A

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

B

2-nitrobutane
600-24-8, 116783-22-3

2-nitrobutane

Conditions
ConditionsYield
With ammonium hydroxide; dihydrogen peroxide In methanol at 70℃; under 760.051 Torr; Green chemistry; Overall yield = 68 %Chromat.; chemoselective reaction;
SEC-BUTYLAMINE
33966-50-6

SEC-BUTYLAMINE

A

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

B

N-sec-butylidene-sec-butylamine
38836-40-7

N-sec-butylidene-sec-butylamine

Conditions
ConditionsYield
With oxygen In neat (no solvent) at 99.84℃; under 6000.6 Torr; for 5h; Autoclave; Green chemistry;
α-isocyanatomethylmethyldimethoxysilane

α-isocyanatomethylmethyldimethoxysilane

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

{[dimethoxy(methyl)silyl]methyl}carbamoylmethylethylketonoxime

{[dimethoxy(methyl)silyl]methyl}carbamoylmethylethylketonoxime

Conditions
ConditionsYield
With potassium hydroxide at 60℃; for 2h;100%
(isocyanatomethyl)trimethoxysilane

(isocyanatomethyl)trimethoxysilane

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

[(trimethoxy-silyl)methyl]carbamoylmethylethylketonoxime

[(trimethoxy-silyl)methyl]carbamoylmethylethylketonoxime

Conditions
ConditionsYield
Borchi-catalyst at 80℃; for 2h;100%
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

acrylic acid 2-isocyanatoethyl ester
13641-96-8

acrylic acid 2-isocyanatoethyl ester

2-(O-[1'-methylpropylideneamino]carboxyamino)ethyl acrylate

2-(O-[1'-methylpropylideneamino]carboxyamino)ethyl acrylate

Conditions
ConditionsYield
With 2,6-di-tert-butyl-4-methyl-phenol at 10 - 20℃; for 6h;99%
With 2,6-di-tert-butyl-4-methyl-phenol at 10 - 20℃; for 6h; Temperature; Enzymatic reaction;
caprinaldehyde
112-31-2

caprinaldehyde

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

n-decanal oxime
13372-74-2

n-decanal oxime

Conditions
ConditionsYield
With sulfuric acid In water at 40℃; for 24h; Reagent/catalyst; Inert atmosphere; Green chemistry;99%
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

butanoic acid ethyl ester
105-54-4

butanoic acid ethyl ester

C8H15NO2

C8H15NO2

Conditions
ConditionsYield
With sodium ethanolate at 100℃; under 75.0075 Torr; for 5h; Large scale;99%
o-fluorobenzyl bromide
446-48-0

o-fluorobenzyl bromide

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

O-(o-fluorobenzyl)-2-butanone oxime

O-(o-fluorobenzyl)-2-butanone oxime

Conditions
ConditionsYield
Stage #1: ethyl methyl ketone oxime With potassium hydroxide; lithium hydroxide In N,N-dimethyl acetamide; water at 50℃;
Stage #2: o-fluorobenzyl bromide In N,N-dimethyl acetamide; water at 65℃; for 2.16667h;
98.5%
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

butanoic acid methyl ester
623-42-7

butanoic acid methyl ester

C8H15NO2

C8H15NO2

Conditions
ConditionsYield
With sodium ethanolate at 85℃; under 52.5053 Torr; for 3.5h; Large scale;98.4%
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

Methyltrimethoxysilan
1185-55-3

Methyltrimethoxysilan

2-butanone O,O',O"-(methylsilylidyne)trioxime

2-butanone O,O',O"-(methylsilylidyne)trioxime

Conditions
ConditionsYield
With toluene-4-sulfonic acid at 85 - 153℃; for 7h; Temperature;98.3%
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

butanone
78-93-3

butanone

Conditions
ConditionsYield
With aluminum oxide; tripropylammonium fluorochromate (VI) In dichloromethane for 1h;98%
With periodic acid at 20℃; for 0.0166667h;98%
With perchloric acid; dihydrogen peroxide; potassium bromide; ammonium molybdate tetrahydrate In water at 20℃; for 1h;98%
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

sodium monochloroacetic acid
3926-62-3

sodium monochloroacetic acid

2-[(butan-2-ylideneamino)oxy]ethanoic acid
98548-96-0

2-[(butan-2-ylideneamino)oxy]ethanoic acid

Conditions
ConditionsYield
With potassium hydroxide In water; acetone at 20 - 60℃; for 2.25h; Solvent; Temperature;98%
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

benzyl bromide
100-39-0

benzyl bromide

O-benzylhydoxylamine hydrochloride
2687-43-6

O-benzylhydoxylamine hydrochloride

Conditions
ConditionsYield
Stage #1: ethyl methyl ketone oxime; benzyl bromide With sodium ethanolate In ethanol at 40℃; for 1h;
Stage #2: With dioctyltin dilaurate In ethanol at 40℃; for 6h;
Stage #3: With hydrogenchloride In water Temperature; Reagent/catalyst; Solvent;
97.4%
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

2-nitrobutane
600-24-8, 116783-22-3

2-nitrobutane

Conditions
ConditionsYield
With dihydrogen peroxide; potassium hydrogencarbonate In tert-butyl alcohol at 65℃; under 375.038 Torr;97%
With sodium perborate hexahydrate In acetic acid at 55℃; for 6.5h;33%
(i) Cl2, (ii) O2, O3, (iii) (nBu)3SnH; Multistep reaction;
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

3-Chlorobenzaldehyde
587-04-2

3-Chlorobenzaldehyde

(E)-3-chlorobenzaldehyde oxime
3717-33-7, 34158-71-9, 4006-79-5

(E)-3-chlorobenzaldehyde oxime

Conditions
ConditionsYield
With perchloric acid In water at 23℃; for 24h; Reagent/catalyst; Inert atmosphere; Green chemistry;97%
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

2-Chloro-2-nitrosobutane
681-01-6

2-Chloro-2-nitrosobutane

Conditions
ConditionsYield
With chloroethane; chlorine at -40℃; for 0.25h;96%
With hydrogenchloride; chlorine
With diethyl ether; nitrosylchloride
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

diphenylphosphinodithioic acid
1015-38-9

diphenylphosphinodithioic acid

S-<1-(hydroxyamino)-2-methylpropyl> diphenylphosphinodithioate
75320-70-6

S-<1-(hydroxyamino)-2-methylpropyl> diphenylphosphinodithioate

Conditions
ConditionsYield
In diethyl ether for 3h;96%
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

N,N'-dichlorobis(2,4,6-trichlorodiphenyl)urea
2899-02-7

N,N'-dichlorobis(2,4,6-trichlorodiphenyl)urea

A

2-Chloro-2-nitrosobutane
681-01-6

2-Chloro-2-nitrosobutane

B

bis(2,4,6-trichlorodiphenyl)urea
20632-35-3

bis(2,4,6-trichlorodiphenyl)urea

Conditions
ConditionsYield
In acetonitrile at 20℃; for 0.25h;A 96%
B n/a
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

(chloromethyl)trichlorosilane
1558-25-4

(chloromethyl)trichlorosilane

chloromethyltris(methylethylketoxime)silane

chloromethyltris(methylethylketoxime)silane

Conditions
ConditionsYield
In hexane at 20℃; for 3h; Inert atmosphere;95%
In Petroleum ether at 25℃; for 4h; Solvent; Temperature;
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

2-chloro-benzaldehyde
89-98-5

2-chloro-benzaldehyde

(E)-2-chlorobenzaldehyde oxime
3717-26-8, 3717-27-9, 3717-28-0

(E)-2-chlorobenzaldehyde oxime

Conditions
ConditionsYield
With perchloric acid In water at 23℃; for 24h; Reagent/catalyst; Inert atmosphere; Green chemistry;95%
thiophene-2-carbaldehyde
98-03-3

thiophene-2-carbaldehyde

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

thiophene-2-carbaldehyde oxime
38266-87-4

thiophene-2-carbaldehyde oxime

Conditions
ConditionsYield
With perchloric acid In water at 23℃; for 24h; Reagent/catalyst; Inert atmosphere; Green chemistry;95%
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

N,N,N,N,-tetramethylethylenediamine
110-18-9

N,N,N,N,-tetramethylethylenediamine

(butan-2-ylidene)(methoxy)amine
27685-12-7

(butan-2-ylidene)(methoxy)amine

Conditions
ConditionsYield
Stage #1: N,N,N,N,-tetramethylethylenediamine With copper(l) chloride at 20℃;
Stage #2: ethyl methyl ketone oxime With N,N,N,N,N,N-hexamethylphosphoric triamide; copper(l) chloride In dimethyl sulfoxide at 15℃; for 0.5h; Inert atmosphere;
Stage #3: With potassium carbonate In dichloromethane at 15℃; for 5.16667h; Reagent/catalyst; Temperature;
95%
titanium(IV) isopropylate
546-68-9

titanium(IV) isopropylate

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

[Ti(OiPr)2(ethyl methyl ketoximate)2]2

[Ti(OiPr)2(ethyl methyl ketoximate)2]2

Conditions
ConditionsYield
In dichloromethane byproducts: iPrOH; (Ar), ethyl methyl ketoxime dissolved in CH2Cl2 at room temp., treated dropwise with 0.5 equiv. of Ti complex; evapd. (vac.), redissolved (CH2Cl2), crystd. for 1 d at 0°C, washed (pentane at -20°C), dried (vac.);94%
3-phenyl-propionaldehyde
104-53-0

3-phenyl-propionaldehyde

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

3-phenylpropanal oxime
1197-50-8

3-phenylpropanal oxime

Conditions
ConditionsYield
With perchloric acid In water at 23℃; for 24h; Reagent/catalyst; Inert atmosphere; Green chemistry;93%
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

cyclohexanecarbaldehyde
2043-61-0

cyclohexanecarbaldehyde

Cyclohexanone oxime
100-64-1

Cyclohexanone oxime

Conditions
ConditionsYield
With perchloric acid In water for 24h; Reagent/catalyst; Inert atmosphere; Reflux; Green chemistry;93%
4-Trifluoromethylbenzaldehyde
455-19-6

4-Trifluoromethylbenzaldehyde

ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

(E)-4-(trifluoromethyl)benzaldoxime
16939-49-4, 24652-60-6, 66046-34-2

(E)-4-(trifluoromethyl)benzaldoxime

Conditions
ConditionsYield
With perchloric acid In water at 23℃; for 24h; Reagent/catalyst; Inert atmosphere; Green chemistry;92%
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

β-naphthaldehyde
66-99-9

β-naphthaldehyde

(E)-2-naphthaldehyde oxime
51873-98-4

(E)-2-naphthaldehyde oxime

Conditions
ConditionsYield
With perchloric acid In water at 23℃; for 24h; Reagent/catalyst; Inert atmosphere; Green chemistry;92%
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

sodium
7440-23-5

sodium

trimethylantimony(V) dibromide
5835-64-3, 24606-08-4, 91002-43-6

trimethylantimony(V) dibromide

(CH3)3Sb(ONC(CH3)(C2H5))2
79730-22-6

(CH3)3Sb(ONC(CH3)(C2H5))2

Conditions
ConditionsYield
In benzene byproducts: NaBr; absence of moisture; addn. of Sb-compd. to 2 equiv. of sodium oximate (prepd. from oxime and Na), refluxing; distn. (reduced pressure); elem. anal.;91%
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

benzaldehyde
100-52-7

benzaldehyde

Conditions
ConditionsYield
With perchloric acid In water at 23℃; for 24h; Reagent/catalyst; Inert atmosphere; Green chemistry;91%
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

4-fluorobenzaldehyde
459-57-4

4-fluorobenzaldehyde

(E)-4-fluorobenzaldehyde oxime
459-23-4

(E)-4-fluorobenzaldehyde oxime

Conditions
ConditionsYield
With perchloric acid In water at 23℃; for 24h; Reagent/catalyst; Inert atmosphere; Green chemistry;90%
ethyl methyl ketone oxime
96-29-7

ethyl methyl ketone oxime

4-chlorobenzaldehyde
104-88-1

4-chlorobenzaldehyde

4-chlorobenzaldehyde oxime
3717-24-6

4-chlorobenzaldehyde oxime

Conditions
ConditionsYield
With perchloric acid In water at 23℃; for 24h; Reagent/catalyst; Inert atmosphere; Green chemistry;90%

2-Butanone oxime Chemical Properties

Molecular Structure:

Molecular Formula: C4H9NO
Molecular Weight: 87.1204
IUPAC Name: (NZ)-N-Butan-2-ylidenehydroxylamine
Synonyms of Methyl ethyl ketoxime (CAS NO.96-29-7): 2-Butanone oxime ; 4-01-00-03250 (Beilstein Handbook Reference) ; BRN 1698241 ; Butanone oxime ; CCRIS 1382 ; EINECS 202-496-6 ; Ethyl methyl ketone oxime ; Ethyl-methylketonoxim ; Ethyl-methylketonoxim [Czech] ; MEK-oxime ; Methyl ethyl ketone oxime ; Methyl ethyl ketoxime ; NSC 442 ; Skino #2 ; Troykyd anti-skin B ; USAF AM-3 ; USAF EK-906
CAS NO: 96-29-7
Classification Code: Mutation data ; Skin / Eye Irritant ; Tumor data
Melting point: -30 °C 
Index of Refraction: 1.421
Molar Refractivity: 24.51 cm3
Molar Volume: 96.5 cm3
Surface Tension: 26.5 dyne/cm
Density: 0.9 g/cm3
Flash Point: 60 °C
Enthalpy of Vaporization: 42.94 kJ/mol
Boiling Point: 152.5 °C at 760 mmHg
Vapour Pressure: 1.88 mmHg at 25°C

2-Butanone oxime Uses

 Methyl ethyl ketoxime (CAS NO.96-29-7) can be used for preventing crust of various oil-base lacquer, alkyd paints, epoxy ester paint during the storage and handling , also can be used for silicon curing agent .

2-Butanone oxime Production

 Methyl ethyl ketoxime (CAS NO.96-29-7) is derived by the reaction of methyl ethyl ketone and hydroxylamine hydrochloride. It also can be derived from reaction of methyl ethyl ketone and hydroxylamine sulfate.

2-Butanone oxime Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 200mg/kg (200mg/kg)   National Technical Information Service. Vol. AD277-689,
mouse LD50 oral 1gm/kg (1000mg/kg)   National Technical Information Service. Vol. OTS0524679,
rabbit LD50 skin 200uL/kg (0.2mL/kg)   National Technical Information Service. Vol. OTS0529835,
rat LC inhalation > 50gm/m3/4H (50000mg/m3) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) National Technical Information Service. Vol. OTS0524693,
rat LD skin > 2gm/kg (2000mg/kg)   National Technical Information Service. Vol. OTS0530016,
rat LD50 oral 930mg/kg (930mg/kg)   Office of Toxic Substances Report. Vol. OTS,
rat LD50 subcutaneous 2702mg/kg (2702mg/kg)   Nagoya Journal of Medical Science. Vol. 29, Pg. 393, 1967.

2-Butanone oxime Consensus Reports

Reported in EPA TSCA Inventory.

2-Butanone oxime Safety Profile

Safety Information of Methyl ethyl ketoxime (CAS NO.96-29-7):
Hazard Codes: Xn ,T
Risk Statements: 21-40-41-43-52/53-48/25 
R21: Harmful in contact with skin. 
R40: Limited evidence of a carcinogenic effect. 
R41: Risk of serious damage to the eyes. 
R43: May cause sensitization by skin contact. 
R52/53: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. 
R48: Danger of serious damage to health by prolonged exposure.
R25: Toxic if swallowed.
Safety Statements:13-23-26-36/37/39-61-45-25 
S13: Keep away from food, drink and animal foodstuffs. 
S23: Do not breathe vapour. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection. 
S61: Avoid release to the environment. Refer to special instructions / safety data sheets. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S25: Avoid contact with eyes.
RIDADR:UN 1993 3/PG 3
WGK Germany:1
RTECS:EL9275000
HazardClass:3
PackingGroup:III
HS Code:29280090
Poison by intraperitoneal route. Moderately toxic by subcutaneous route. May explode if heated. Reacts with sulfuric acid to form an explosive product. When heated to decomposition it emits toxic fumes of NOx.

2-Butanone oxime Standards and Recommendations

DOT Classification:  3; Label: Flammable Liquid

2-Butanone oxime Specification

First Aid Measures of Methyl ethyl ketoxime (CAS NO.96-29-7):
Eyes:Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:Get medical aid. Wash mouth out with water.
Inhalation:Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Storage of Methyl ethyl ketoxime (CAS NO.96-29-7):
Store in a cool, dry place. Store in a tightly closed container.

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