Benzylamine supplier | CasNO.100-46-9

Name
Benzylamine
EINECS 202-854-1
CAS No. 100-46-9
Article Data960
CAS DataBase
Density 0.979 g/cm³
Solubility Soluble in water
Melting Point -30 °C
Formula C₇H₉N
Boiling Point 185 °C at 760 mmHg
Molecular Weight 107.155
Flash Point 60 °C
Transport Information UN 2735 8/PG 2
Appearance colourless liquid with an ammoniacal odour
Safety 26-36/37/39-45
Risk Codes 21/22-34
Molecular Structure
Hazard Symbols C
Synonyms phenylmethanamine;1-phenylmethanamine;Monobenzylamine;.omega.-Aminotoluene;benzylazanium;(Phenylmethyl)amine;benzenemethanamine;.alpha.-Aminotoluene;Benzylamine(BA);Benzyl amine;N-Benzylamine;Benzylamine 99%;
PSA 26.02000
LogP 1.84560

Synthetic route

: 622-79-7
benzyl azide

: 100-46-9
benzylamine

Conditions

Conditions	Yield
With Zn(BH4)2(Ph3P)2 In tetrahydrofuran for 0.25h; Reduction; Heating;	100%
With sodium tetrahydroborate; tin bis(1,2-benzenedithiolate) In tetrahydrofuran; phosphate buffer at 10℃; for 0.5h; pH=10; Product distribution; Further Variations:; pH-values; Solvents; Reduction;	100%
With (Sn(SPh)3)(Et3N) In benzene at 15℃; for 0.0833333h;	99%

: 100-47-0
benzonitrile

: 100-46-9
benzylamine

Conditions

Conditions	Yield
With lithium borohydride; 9-methoxy-9-BBN In diethyl ether at 25℃; for 5h; Product distribution; rate of reduction;	100%
With borane N-ethyl-N-isopropylaniline complex In tetrahydrofuran for 0.1h; Heating;	100%
With hydrogen; palladium In methanol at 20℃; for 432h;	100%

: 104669-74-1
benzyl carbamic acid allyl ester

: 100-46-9
benzylamine

Conditions

Conditions	Yield
With diethylamine; palladium diacetate; trisodium tris(3-sulfophenyl)phosphine In water; acetonitrile for 0.166667h; Ambient temperature;	100%

: 4383-22-6
Allylbenzylamine

: 100-46-9
benzylamine

Conditions

Conditions	Yield
With Thiosalicylic acid; 1,4-di(diphenylphosphino)-butane; bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran at 60℃; for 0.5h; effect of temperature on deprotection of various primary and secondary allylamines;	100%
With Thiosalicylic acid; 1,4-di(diphenylphosphino)-butane; bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran at 60℃; for 0.5h;	100%
With polymethylhydrosiloxane; zinc(II) chloride; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran at 20℃;	92%
With 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); diisobutylaluminium hydride In toluene for 1h; Ambient temperature;	66%

: 4383-26-0
N,N-di-2-propenylbenzylamine

: 100-46-9
benzylamine

Conditions

Conditions	Yield
With Thiosalicylic acid; 1,4-di(diphenylphosphino)-butane; bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran at 60℃; for 0.5h;	100%
With 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); diisobutylaluminium hydride In toluene for 1h; Ambient temperature;	79%

: 42116-44-9
N-tert-butoxycarbonylbenzylamine

: 100-46-9
benzylamine

Conditions

Conditions	Yield
With methanol; Acetyl bromide In dichloromethane at 25℃; for 0.333333h;	100%
With 3-butyl-l-methyl-1H-imidazol-3-iumtrifloroacetate In 1,4-dioxane; water at 80 - 82℃; for 4h;	98%
With nitric acid In dichloromethane at 0℃; for 1h;	95%

: 921-01-7, 3374-22-9, 4371-52-2, 40143-64-4, 40143-66-6, 40143-69-9, 52-90-4
rac-cysteine

: N-benzyl-2,4-dinitro-benzenesulfonamide

A: 3165-76-2
S-(2,4-Dinitrophenyl)-cystein

B: 7446-09-5
sulfur dioxide

C: 100-46-9
benzylamine

Conditions

Conditions	Yield
In aq. phosphate buffer for 0.5h; pH=7.4;	A n/a B 100% C n/a

...Expand

: 52826-45-6
(benzylimino)triphenylphosphorane

: 100-46-9
benzylamine

Conditions

Conditions	Yield
With phenylsilane In toluene at 111℃; for 12h;	100%

: 100-52-7
benzaldehyde

: 100-46-9
benzylamine

Conditions

Conditions	Yield
With ammonia; hydrogen In methanol at 90℃; under 15001.5 Torr; for 4h; Solvent; Temperature; Pressure; Autoclave;	99.7%
With Candida boidinii formate dehydrogenase; Geobacillus stearothermophilus ε‐deaminating L‐lysine dehydrogenase variant 1; nicotinamide adenine dinucleotide In aq. buffer at 30℃; for 24h; pH=8.5; Reagent/catalyst; Enzymatic reaction;	99%
With ammonium hydroxide; hydrogen In ethanol at 130℃; under 7500.75 Torr; for 12h; Autoclave;	96.9%

: 1576-37-0
N-benzyl-p-toluenesulfonamide

: 100-46-9
benzylamine

Conditions

Conditions	Yield
Stage #1: N-benzyl-p-toluenesulfonamide With n-butyllithium In tetrahydrofuran at 0℃; Stage #2: With naphthalene; lithium In tetrahydrofuran at -78 - 20℃;	99%
Stage #1: N-benzyl-p-toluenesulfonamide With n-butyllithium In tetrahydrofuran at 0℃; for 0.166667h; Inert atmosphere; Stage #2: With naphthalene; lithium In tetrahydrofuran at -78 - 25℃; Stage #3: With water In tetrahydrofuran	99%
With naphthalene; water; lithium 1.) THF, -78 deg C, 2 h; Yield given. Multistep reaction;

: 383865-57-4
4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl-amine

A: 1-Benzyl-3-(4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-urea

B: 100-46-9
benzylamine

Conditions

Conditions	Yield
	A 99% B n/a

: 6343-54-0
N-benzylformamide

: 100-46-9
benzylamine

Conditions

Conditions	Yield
With sodium ethanolate In methanol at 80℃; for 2h;	99%
With sodiumsulfide nonahydrate In water at 100℃; for 12h;	86%
Multi-step reaction with 2 steps 1: 3 h / Reflux 2: triphenylphosphine; triethylamine / dichloromethane; tetrachloromethane / 4 h / Reflux; Inert atmosphere View Scheme

: 622-42-4
1-nitro-1-phenylmethane

: 100-46-9
benzylamine

Conditions

Conditions	Yield
With 5%-palladium/activated carbon; hydrogen; ammonium formate In methanol under 2068.65 Torr; Flow reactor;	98%
With palladium on activated charcoal; tetrabutylammomium bromide; water; sodium hydroxide; silicon at 100℃; for 6h; Reagent/catalyst;	94%
With hydrazine hydrate In dichloromethane at 20℃; for 1h;	71%

: 122954-29-4
benzylammonium O-ethylstyrylphosphonate

A: 5849-49-0
styrylphosphonic acid ethylester

B: 100-46-9
benzylamine

Conditions

Conditions	Yield
With sodium hydroxide at 20℃; for 0.5h;	A 98% B 83%

: 3378-73-2
1-phenyl-N-tritylethanamine

: 100-46-9
benzylamine

Conditions

Conditions	Yield
With ammonium cerium (IV) nitrate; water; acetic acid In dichloromethane at 20℃; for 7.5h; Inert atmosphere;	98%
With water; ytterbium(III) triflate In tetrahydrofuran at 20℃; Product distribution; Further Variations:; Catalysts; Reagents; Hydrolysis;	93%

: 54535-21-6
2-(benzylamino-methylene)-malonic acid diethyl ester

: 100-46-9
benzylamine

Conditions

Conditions	Yield
With ethylenediamine In ethanol at 20℃; for 0.75h;	98%

: N-benzyl-3,3-dimethoxypropylsulfonamide

: 100-46-9
benzylamine

Conditions

Conditions	Yield
Stage #1: N-benzyl-3,3-dimethoxypropylsulfonamide With p-toluenesulfonic acid monohydrate In water; acetone at 0 - 20℃; for 6h; Stage #2: With sodium hydroxide In methanol; water; acetone at 0 - 20℃; for 1.08333h;	98%

: 932-90-1
Benzaldoxime

: 100-46-9
benzylamine

Conditions

Conditions	Yield
With sodium hydrogensulfate monohydrate; molybdenum(V) chloride; sodium cyanoborohydride In N,N-dimethyl-formamide for 1.5h; Reflux;	96%
With sodium tetrahydroborate at 20℃; for 0.0333333h; neat (no solvent, solid phase);	94%
With iron oxide; zirconium(IV) chloride; sodium cyanoborohydride In neat (no solvent) at 75 - 80℃; for 0.25h; Reagent/catalyst; Temperature;	93%

: 100-51-6
benzyl alcohol

: 100-46-9
benzylamine

Conditions

Conditions	Yield
With sodium azide; triphenylphosphine In dichloromethane; N,N-dimethyl-formamide at 90℃; for 4h; Substitution; Mitsunobu reaction; Staudinger reaction;	96%
With ammonia In toluene at 110℃; under 5250.53 Torr; for 20h;	91%
With (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); ammonia; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In tert-Amyl alcohol at 140℃; for 20h; Inert atmosphere; Cooling;	87%

: 33148-47-9
4-allyloxy-benzonitrile

A: 60758-84-1
4-cyanophenyl propyl ether

B: 100-46-9
benzylamine

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal; ethylenediamine In tetrahydrofuran at 20℃; for 24h; atmospheric pressure;	A 96% B n/a

: 100-39-0
benzyl bromide

: 100-46-9
benzylamine

Conditions

Conditions	Yield
With 5-methyl-1,3,4-thiadiazol-2-amine; triethylamine In ethanol; water at 25℃; for 1h;	96%
Multi-step reaction with 2 steps 1.1: n-butyllithium / tetrahydrofuran / Inert atmosphere 1.2: 8 h / Inert atmosphere 1.3: 2 h / 60 °C / Inert atmosphere 2.1: titanium(III) chloride; water / tetrahydrofuran / pH 10 / Reflux; Alkaline aq. solution; Inert atmosphere View Scheme
Multi-step reaction with 2 steps 1: potassium carbonate / N,N-dimethyl-formamide / 3 h / 80 °C 2: hydrogenchloride / water / 3 h / 100 °C View Scheme
Multi-step reaction with 2 steps 1.1: potassium carbonate / 1 h / Milling 1.2: 1 h / Milling 2.1: ethylenediamine / neat (no solvent) / Milling View Scheme

: 5817-70-9
methyl N-benzylcarbamate

A: 67-56-1
methanol

B: 100-46-9
benzylamine

Conditions

Conditions	Yield
With C25H19BrMnN2O2P; potassium tert-butylate; hydrogen In toluene at 130℃; under 15001.5 Torr; for 48h;	A 98 %Spectr. B 96%

: 7387-69-1
N-benzyl-2,2,2-trifluoroacetamide

: 100-46-9
benzylamine

Conditions

Conditions	Yield
With potassium hydroxide at 20℃; for 0.25h;	95%

: 5001-26-3
2-hydroxy-N-(benzyl)benzylamine

A: C21H18O3

B: 100-46-9
benzylamine

Conditions

Conditions	Yield
at 220℃; under 10 Torr; for 0.0833333h; Product distribution; pyrolysis without solvent, isolated as sulfate;	A n/a B 95%

: 1-naphthylmethyl N-benzyl carbamate

: 100-46-9
benzylamine

Conditions

Conditions	Yield
With ammonium formate; 1,2-bis-(diphenylphosphino)ethane; bis(dibenzylideneacetone)-palladium(0) In dimethyl sulfoxide at 80℃; for 12h; deprotection;	95%

: 2621-78-5
ethyl N-benzylcarbamate

: 100-46-9
benzylamine

Conditions

Conditions	Yield
With ammonium bromide; 3-azapentane-1,5-diamine at 110℃; for 5h; Temperature; Microwave irradiation;	95%

: 2142-01-0
N-benzylphthalimide

A: 612-14-6
phthalyl alcohol

B: 100-46-9
benzylamine

Conditions

Conditions	Yield
With [RuCl2(2-(diphenylphosphino)-N-((6-((diphenylphosphino)methyl)pyridin-2-yl)methyl)ethan-1-amine)]; potassium tert-butylate; hydrogen In tetrahydrofuran at 100℃; under 37503.8 Torr; for 20h; Catalytic behavior; Autoclave; chemoselective reaction;	A 95% B 87%
With C25H19BrMnN2O2P; potassium tert-butylate; hydrogen In tetrahydrofuran at 130℃; under 22502.3 Torr; for 48h; Mechanism; Inert atmosphere; Glovebox; Autoclave; Green chemistry;	A 94% B 92%
With [Ru(PtBuNNHtBu)H(CO)Cl]; potassium tert-butylate; hydrogen In tetrahydrofuran at 110℃; under 15001.5 Torr; for 24h; Autoclave;
With C25H19BrMnN2O2P; potassium tert-butylate; hydrogen In 1,4-dioxane at 130℃; under 22502.3 Torr; for 48h; Catalytic behavior; Solvent; Reagent/catalyst; Pressure; Inert atmosphere; Glovebox; Autoclave; Green chemistry;	A 92 %Spectr. B 97 %Spectr.

: 100-44-7
benzyl chloride

: 100-46-9
benzylamine

Conditions

Conditions	Yield
With copper(ll) sulfate pentahydrate; ammonium hydroxide In PEG1000-DIL; methyl cyclohexane at 60℃; for 3h;	94%
With 5-methyl-1,3,4-thiadiazol-2-amine; triethylamine In ethanol; water at 25℃; for 1h; Reagent/catalyst;	94%
With hydrogenchloride; potassium hydride; 1,1,3,3-tetramethyldisilazane In tetrahydrofuran at 0 - 25℃; multistep selective monoamination reaction of various alkyl halides;	88%

: 119592-74-4
N-benzyl-2,2,6,6-tetramethyl-2,6-disilapiperidine

: 100-46-9
benzylamine

Conditions

Conditions	Yield
In hydrogenchloride for 8h; Heating;	94%

: 674-82-8
4-methyleneoxetan-2-one

: 100-46-9
benzylamine

: 882-36-0
N-benzyl-3-oxobutanamide

Conditions

Conditions	Yield
In dichloromethane at 0 - 20℃;	100%
In dichloromethane at 0 - 20℃;	100%
In dichloromethane at 0 - 20℃;	100%

: 96-48-0
4-butanolide

: 100-46-9
benzylamine

: 19340-88-6
N-benzyl-4-hydroxybutanamide

Conditions

Conditions	Yield
With bis(trifluoromethane)sulfonimide lithium In chloroform at 85℃; for 40h;	100%
Stage #1: benzylamine With diisobutylaluminium hydride In tetrahydrofuran; toluene Stage #2: 4-butanolide In tetrahydrofuran at 20℃; for 0.5h;	98%
In benzene for 12h; Reflux;	98%

: 98-01-1
furfural

: 100-46-9
benzylamine

: 4393-11-7
N-benzyl-1-(furan-2-yl)methanimine

Conditions

Conditions	Yield
With copper(II) bis(trifluoromethanesulfonate) In water at 20℃; for 0.0166667h;	100%
In water at 20℃; for 2h;	93%
In dichloromethane Inert atmosphere; Molecular sieve;	81%

: 286-20-4
cyclohexane-1,2-epoxide

: 100-46-9
benzylamine

: 40571-86-6, 40571-87-7, 51925-39-4, 131164-07-3, 141553-09-5
rac-(1R,2R)-2-(benzylamino)cyclohexanol

Conditions

Conditions	Yield
bismuth(lll) trifluoromethanesulfonate at 160℃; for 0.25h; microwave irradiation;	100%
at 150℃; Neat (no solvent);	99%
With zinc(II) perchlorate hexahydrate at 80℃; for 1h;	97%

: 3282-30-2
pivaloyl chloride

: 100-46-9
benzylamine

: 26209-45-0
N-benzyl-2,2-dimethylpropanamide

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 25℃; for 1h;	100%
With triethylamine In dichloromethane at 0 - 20℃; for 4h; Inert atmosphere;	100%
With 1-methyl-1H-imidazole In dichloromethane at 0℃; Inert atmosphere;	99%

: 108-94-1
cyclohexanone

: 100-46-9
benzylamine

: 4383-25-9
N-benzylcyclohexylamine

Conditions

Conditions	Yield
With formic acid; Cp*IrCl(N-(phenyl(pyridin-2-yl)methyl)methanesulfonamide)complex In ethyl acetate at 40℃; for 18h; Reagent/catalyst; Inert atmosphere;	100%
Stage #1: cyclohexanone; benzylamine With formic acid; chlorido(8-quinolinolato-k2N,O)(η5-pentamethylcyclopentadienyl)iridium(III) In ethyl acetate at 0 - 40℃; Inert atmosphere; Schlenk tube; Cooling with ice; Stage #2: With sodium hydrogencarbonate In water; ethyl acetate Product distribution / selectivity;	98%
With 4 A molecular sieve; borane pyridine complex In methanol for 16h;	96%

: 104-87-0
4-methyl-benzaldehyde

: 100-46-9
benzylamine

: 24431-15-0
N-benzyl-p-tolylmethanimine

Conditions

Conditions	Yield
In chloroform at 20℃; for 1h;	100%
for 6h; Kinetics; Molecular sieve; Reflux;	100%
With magnesium sulfate In dichloromethane at 20℃; Inert atmosphere;	65%

: 104-88-1
4-chlorobenzaldehyde

: 100-46-9
benzylamine

: 130517-96-3, 13540-93-7
N-(4-chlorobenzylidene)benzylamine

Conditions

Conditions	Yield
for 6h; Molecular sieve; Reflux;	100%
In ethanol at 20℃;	94%
In dichloromethane at 20℃; for 16h; Molecular sieve;	92%

: 623-27-8
terephthalaldehyde,

: 100-46-9
benzylamine

: 20941-14-4
1,4-bis(benzyliminomethyl)benzene

Conditions

Conditions	Yield
In methanol at 20℃;	100%
In methanol at 20℃;	80%

: 622-78-6
Benzyl isothiocyanate

: 100-46-9
benzylamine

: 1424-14-2
dibenzyl thiourea

Conditions

Conditions	Yield
In hexane at 20℃; for 2h;	100%
In dichloromethane at 20℃;	98%
In chloroform for 0.5h; Heating;	88%

: 100-52-7
benzaldehyde

: 100-46-9
benzylamine

: 780-25-6
N-benzylidene benzylamine

Conditions

Conditions	Yield
In toluene at 120℃; for 24h;	100%
With magnesium sulfate In dichloromethane for 3h; Reflux;	100%
With aluminum oxide at 20℃; for 2.5h;	99%

: 123-11-5
4-methoxy-benzaldehyde

: 100-46-9
benzylamine

: 622-72-0
N-(4-methoxylbenzylidene)benzylamine

Conditions

Conditions	Yield
In chloroform at 20℃; for 1h;	100%
With sodium sulfate In dichloromethane at 20℃;	99%
In chloroform at 20℃; for 1h;	96.8%

: 98-88-4
benzoyl chloride

: 100-46-9
benzylamine

: 1485-70-7
N-benzylbenzamide

Conditions

Conditions	Yield
In tetrahydrofuran at 20℃;	100%
With sodium hydroxide In 1,2-dimethoxyethane; water at 25℃; for 0.5h; pH 10.45;	99%
Stage #1: benzoyl chloride; benzylamine With triethylamine In dichloromethane at 20℃; for 0.333333h; Stage #2: With poly{trans-bicyclo[2.2.1]hept-5-ene-2,3-di(chlorocarbonyl)} In dichloromethane at 20℃; for 0.5h;	99%

: 103-72-0
phenyl isothiocyanate

: 100-46-9
benzylamine

: 726-25-0
1-benzyl-3-phenylthiourea

Conditions

Conditions	Yield
In acetonitrile at 20℃; for 3h;	100%
In acetonitrile at 25℃; for 0.166667h; Milling;	99%
With C64H52CaN6 In neat (no solvent) at 60℃; for 12h; Schlenk technique; Glovebox; Inert atmosphere;	98%

: 77287-34-4, 77287-35-5, 60100-09-6
formamide

: 100-46-9
benzylamine

: 6343-54-0
N-benzylformamide

Conditions

Conditions	Yield
With Iron(III) nitrate nonahydrate In toluene for 2h; Concentration; Reflux;	100%
With H-β-zeolite In neat (no solvent) at 80℃; for 24h; Green chemistry;	99%
at 20 - 120℃; for 15h;	99%

: 78-84-2
isobutyraldehyde

: 100-46-9
benzylamine

: 22483-21-2
isobutylidenebenzylamine

Conditions

Conditions	Yield
With magnesium sulfate In dichloromethane at 20℃; Inert atmosphere;	100%
With aluminum oxide at 20℃; for 7h;	90%
In water Condensation;	65.12%

: 292638-85-8
acrylic acid methyl ester

: 100-46-9
benzylamine

: 23574-01-8
3-benzylamino-propionic acid methyl ester

Conditions

Conditions	Yield
at -40℃; for 12h;	100%
With [HP(HNCH2CH2)3N]NO3 In acetonitrile at 20℃; for 48h; Michael addition;	98%
copper In methanol at 20℃; for 0.3h; Aza-Michael Addition;	98%

: 292638-85-8
acrylic acid methyl ester

: 100-46-9
benzylamine

: 793-19-1
bis(2-methoxycarbonylethyl)benzylamine

Conditions

Conditions	Yield
In methanol at 20℃; for 8h; Reflux;	100%
In methanol Reflux;	99%
In methanol at 34℃; for 72h; Inert atmosphere;	99%

: 79-04-9
chloroacetyl chloride

: 100-46-9
benzylamine

: 2564-06-9
N-benzyl-2-chloroacetamide

Conditions

Conditions	Yield
In dichloromethane	100%
With triethylamine In dichloromethane at 0 - 20℃; for 4h; Inert atmosphere;	98%
With potassium carbonate In dichloromethane Heating;	97%

: 598-21-0
2-Bromoacetyl bromide

: 100-46-9
benzylamine

: 2945-03-1
N-benzyl-2-bromoacetamide

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran at 20℃; for 2h;	100%
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 16h;	99%
In dichloromethane at 0 - 20℃; for 0.5h; Inert atmosphere;	98%

: 98-09-9
benzenesulfonyl chloride

: 100-46-9
benzylamine

: 837-18-3
N-benzylbenzenesulfonamide

Conditions

Conditions	Yield
With triethylamine In dichloromethane 1) 0 deg C, 1 h, 2) room temperature;	100%
With sodium hydroxide In water at 25℃; for 2h; pH 9.6;	99.9%
With Fe3O4-supported (diisopropylamino)acetamide In dichloromethane at 25℃;	98%

: 98-59-9
p-toluenesulfonyl chloride

: 100-46-9
benzylamine

: 1576-37-0
N-benzyl-p-toluenesulfonamide

Conditions

Conditions	Yield
With triethylamine In dichloromethane at 4℃;	100%
With pyridine; dmap In dichloromethane at 0 - 20℃; for 16h;	99%
With triethylamine at 20℃; for 1h; Inert atmosphere;	99%

: 3173-56-6
benzyl isothiocyanate

: 100-46-9
benzylamine

: 1466-67-7
1,3-dibenzylurea

Conditions

Conditions	Yield
In tetrahydrofuran at 10 - 35℃; for 16h;	100%
In dichloromethane at 5℃; for 0.5h;	99%
Multistep reaction;	96%

: 75-15-0
carbon disulfide

: 100-46-9
benzylamine

: 1424-14-2
dibenzyl thiourea

Conditions

Conditions	Yield
at 100℃; for 12h; Ionic liquid; Green chemistry;	100%
aluminum oxide; zinc(II) oxide at 100℃; for 2h; Condensation;	98%
In water at 20℃; for 1.33333h; Solvent; Time; Green chemistry;	97%

: 1013-88-3
Benzophenone imine

: 100-46-9
benzylamine

: 7699-79-8
benzhydrylidene-benzyl-amine

Conditions

Conditions	Yield
In chloroform at 20℃; for 288h;	100%
In dichloromethane for 13h; Inert atmosphere; Reflux;	98.3%
In dichloromethane for 13h; Reflux; Inert atmosphere;	95.3%

: 64-18-6
formic acid

: 100-46-9
benzylamine

: 6343-54-0
N-benzylformamide

Conditions

Conditions	Yield
With sodium hydrogencarbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; ethyl cyanoglyoxylate-2-oxime In water; N,N-dimethyl-formamide at 20℃; for 3h; Reagent/catalyst; Solvent;	100%
With 4-methyl-morpholine; dmap; 2-chloro-4,6-dimethoxy-1 ,3,5-triazine In dichloromethane at 35℃; for 0.1h; microwave irradiation;	99%
With sulfated tungstate at 70℃; for 0.166667h; Neat (no solvent);	99%

: 54221-37-3
diethyl meso-2,5-dibromoadipate

: 100-46-9
benzylamine

: 17740-40-8
diethyl meso-1-benzyl-2,5-pyrrolidinedicarboxylate

Conditions

Conditions	Yield
In toluene for 4h; Reflux;	100%

: 97-65-4
2-methylenesuccinic acid

: 100-46-9
benzylamine

: 5733-86-8
1-benzyl-5-oxopyrrolidine-3-carboxylic acid

Conditions

Conditions	Yield
at 130℃; Inert atmosphere;	100%
	86%
at 130℃; for 2.5h; Inert atmosphere;	82.9%

Benzylamine Chemical Properties

Molecular Structure of Benzylamine (CAS NO.100-46-9):

IUPAC Name: phenylmethanamine
Molecular formula: C₇H₉N
Molecular Weight:107.15
H bond acceptors: 1
H bond donors: 2
Freely Rotating Bonds: 2
Polar Surface Area: 3.24 Å²
Index of Refraction: 1.547
Molar Refractivity: 34.7 cm³
Molar Volume: 109.4 cm³
Surface Tension: 38.8 dyne/cm
Density: 0.979 g/cm³
Flash Point: 60 °C
Enthalpy of Vaporization: 42.12 kJ/mol
Boiling Point: 185 °C at 760 mmHg
Vapour Pressure: 0.713 mmHg at 25°C
EINECS: 202-854-1
Melting point: -30 °C
Product Categories: Pharmaceutical Intermediates; Organics
InChI
InChI=1/C7H9N/c8-6-7-4-2-1-3-5-7/h1-5H,6,8H2
Smiles
c1(ccccc1)CN

Benzylamine Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mammal (species unspecified)	LD50	oral	700mg/kg (700mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(4), Pg. 86, 1974.
mouse	LD50	intraperitoneal	600mg/kg (600mg/kg)		United States Patent Document. Vol. #3816470,

Benzylamine Safety Profile

The Hazard Codes: C
The Risk Statements information:
34: Causes burns
21/22: Harmful in contact with skin and if swallowed
The Safety Statements information:
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
36/37/39: Wear suitable protective clothing, gloves and eye/face protection
RIDADR: UN 2735 8/PG 2

Benzylamine Specification

Benzylamine , with CAS number of 100-46-9, can be called .alpha.-Aminotoluene ; (Aminomethyl)benzene ; (Phenylmethyl)amine ; Benzenemethanamine ; Moringine ; alpha-Aminotoluene . Benzylamine (CAS NO.100-46-9) consists of a benzyl group, attached to an amine functional group. This colorless liquid is a common precursor in organic synthesis.

Product Name

Benzylamine

Synthetic route

Benzylamine Chemical Properties

Benzylamine Toxicity Data With Reference

Benzylamine Safety Profile

Benzylamine Specification

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