Bromoacetic acid supplier

Name
Bromoacetic acid
EINECS 201-175-8
CAS No. 79-08-3
Article Data117
CAS DataBase
Density 1.934 g/cm³
Solubility miscible with water
Melting Point 46-49 °C
Formula C₂H₃BrO₂
Boiling Point 207.036 °C at 760 mmHg
Molecular Weight 138.949
Flash Point 79.013 °C
Transport Information UN 1938/3425
Appearance white to light yellow crystalline mass
Safety 26-36/37/39-45-61-36-16
Risk Codes 23/24/25-35-50-40-36/37/38
Molecular Structure
Hazard Symbols T,C,Xi,F,N
Synonyms Acide bromacetique;
PSA 37.30000
LogP 0.46590

Synthetic route

: 557-68-6
iodobromomethane

: 124-38-9
carbon dioxide

: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
Stage #1: iodobromomethane With isopropylmagnesium chloride In tetrahydrofuran at -78℃; for 0.0166667h; Inert atmosphere; Stage #2: carbon dioxide In tetrahydrofuran at -78℃; for 3h;	100%

: 540-51-2
2-bromoethanol

: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
With 1-hydroxy-1H-1,2,3-benziodoxathiole 1,3,3-trioxide; Oxone; cetyltrimethylammonim bromide In water at 100℃; for 24h; Green chemistry; chemoselective reaction;	90%

: 64-19-7
acetic acid

: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
With N-Bromosuccinimide; sulfuric acid In trifluoroacetic acid at 85℃; for 16h;	88%
With phosphorus; bromine at 100℃;
With hydrogenchloride; bromine at 80 - 90℃;

: 82191-81-9
β-bromocaproic acid

: 75-05-8
acetonitrile

A: 628-73-9
hexanenitrile

B: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
zinc(II) chloride at 280℃; for 1h;	A 81% B n/a

...Expand

: 75-96-7
tribromoacetic acid

A: 110-15-6
succinic acid

B: 64-19-7
acetic acid

C: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
With sodium tetrahydroborate In water at 20℃; for 5h; Green chemistry;	A 80% B 15% C 5%

...Expand

: 64-19-7
acetic acid

A: 110-15-6
succinic acid

B: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
Stage #1: acetic acid With lithium diisopropyl amide In tetrahydrofuran at 0 - 40℃; Inert atmosphere; Stage #2: With N,N-diethyl-N-bromoamine In tetrahydrofuran at 20 - 25℃; for 2h; Inert atmosphere;	A 52% B 13%
Stage #1: acetic acid With lithium diisopropyl amide In tetrahydrofuran at 20 - 25℃; Inert atmosphere; Stage #2: With carbon tetrabromide In tetrahydrofuran at 20 - 25℃; Inert atmosphere;	A 51% B 7%

2-isopropyl-5-methyl-cyclohexyl ester: 2-isopropyl-5-methyl-cyclohexyl ester

: 2216-51-5
(-)-menthol

: 598-21-0
2-Bromoacetyl bromide

A acid bromo acetic 2-isopropyl-5-methylcyclohexyl ester: acid bromo acetic 2-isopropyl-5-methylcyclohexyl ester

B: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
With hydrogenchloride; triethylamine In tetrahydrofuran; hexane; ethyl acetate	A n/a B 51%

...Expand

: 96-32-2
bromoacetic acid methyl ester

: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
With lithium hydroxide monohydrate In tetrahydrofuran at 25℃; for 0.333333h;	32.9%

: 64-69-7
Iodoacetic acid

: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
With caesium bromide at 19.9℃; under 45003600 Torr; Product distribution; under shear deformation (360 deg); other reagents;	7%

: 24298-33-7
1-ethoxy-1,2-dibromo-ethene

: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
With water

: 631-64-1
dibromoacetic acid

: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
bei der elektrochemischen Reduktion unter Verwendung von Blei-Katoden;
With water; iron at 20℃; Kinetics;

: 593-61-3
bromoethyne

: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
With air; ethanol

: 59956-76-2
bromo-acetic acid-(2-chloro-ethyl ester)

: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
Verseifen;

: (dibromo-phenyl-λ4-selanyl)-acetic acid

A: 34837-55-3
Phenylselenyl bromide

B: 1666-13-3
diphenyl diselenide

C: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
beim Erhitzen ueber den Schmelzpunkt;

...Expand

: 108-24-7
acetic anhydride

: 64-19-7
acetic acid

: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
With pyridine; bromine

: 108-24-7
acetic anhydride

: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
With nitrosylsulfuric acid; nitric acid; potassium bromide
With phosphorus; bromine Zersetzung des entstandenen Bromacetylbromids mit Wasser;

: 558-13-4
carbon tetrabromide

: 64-19-7
acetic acid

: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
at 150 - 180℃;

: 141-78-6
ethyl acetate

: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
With bromine at 150℃;

: 685-87-0
Diethyl 2-bromomalonate

: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
With hydrogenchloride

: 106-93-4
ethylene dibromide

: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
With nitric acid

: 79-11-8
chloroacetic acid

: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
With hydrogen bromide at 150℃;

: bromo-acetic acid-(N-nitroso-anilide)

: 71-43-2
benzene

A: 92-52-4
biphenyl

B: 79-08-3
bromoacetic acid

...Expand

: 29921-57-1
isopropyl 2-bromoacetate

A: 79-08-3
bromoacetic acid

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
subtilisin In water at 30℃; Kinetics;

: 35223-80-4
n-propyl bromoacetate

A: 71-23-8
propan-1-ol

B: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
subtilisin In water at 30℃; Kinetics;

: 1113-59-3
bromopyruvic acid

: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
With potassium bromate; cerium (IV) sulfate In sulfuric acid at 20℃; Kinetics; redox measurements;

: 18991-98-5
n-butyl bromoacetate

A: 79-08-3
bromoacetic acid

B: 71-36-3
butan-1-ol

Conditions

Conditions	Yield
subtilisin In water at 30℃; Kinetics;

: 96-32-2
bromoacetic acid methyl ester

A: 67-56-1
methanol

B: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
subtilisin In water at 30℃; Kinetics;
With 2-(di(2-hydroxyethyl)amino)ethanesulfonic acid; esterase from Streptomyces diastatochromogenes In water at 25℃; pH=7.20; Enzyme kinetics;
With 2-(di(2-hydroxyethyl)amino)ethanesulfonic acid; esterase from Pseudomonas fluorescens In water at 25℃; pH=7.20; Enzyme kinetics;
With 2-(di(2-hydroxyethyl)amino)ethanesulfonic acid; lipase from Ophiostoma piliferum In water at 25℃; pH=7.20; Enzyme kinetics;
With 2-(di(2-hydroxyethyl)amino)ethanesulfonic acid; lipase from Bacillus thermocatenulanatus In water at 40℃; pH=7.20; Enzyme kinetics;

: 105-36-2
ethyl bromoacetate

A: 64-17-5
ethanol

B: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
subtilisin In water at 30℃; Kinetics;
With 2-(di(2-hydroxyethyl)amino)ethanesulfonic acid; esterase from Streptomyces diastatochromogenes In water at 25℃; pH=7.20; Enzyme kinetics;
With 2-(di(2-hydroxyethyl)amino)ethanesulfonic acid; esterase from Pseudomonas fluorescens In water at 25℃; pH=7.20; Enzyme kinetics;
With 2-(di(2-hydroxyethyl)amino)ethanesulfonic acid; lipase from Ophiostoma piliferum In water at 25℃; pH=7.20; Enzyme kinetics;
With 2-(di(2-hydroxyethyl)amino)ethanesulfonic acid; lipase from Bacillus thermocatenulanatus In water at 40℃; pH=7.20; Enzyme kinetics;

: C2H3ClHgO6

: 79-08-3
bromoacetic acid

Conditions

Conditions	Yield
With bromine In chloroform Yield given;

: 79-08-3
bromoacetic acid

: 100-51-6
benzyl alcohol

: 5437-45-6
Benzyl bromoacetate

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In benzene at 120℃; for 24h;	100%
With toluene-4-sulfonic acid In benzene at 120℃; for 24h; Inert atmosphere;	100%
With toluene-4-sulfonic acid In benzene at 120℃; for 24h;	100%

: 2216-51-5
(-)-menthol

: 79-08-3
bromoacetic acid

: 16832-20-5, 32815-12-6, 55284-67-8
(1R,2S,5R)-menthol bromoacetate

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In dichloromethane for 3h;	100%
With dmap; dicyclohexyl-carbodiimide at 100℃; for 3h;	96%
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0℃; for 2h;	91%

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 79-08-3
bromoacetic acid

: 42014-51-7
bromoacetic acid N-hydroxusuccinimidyl ester

Conditions

Conditions	Yield
With dicyclohexyl-carbodiimide In 1,4-dioxane at 20℃; for 2h;	100%
With dicyclohexyl-carbodiimide In tetrahydrofuran at 5℃; for 144h;	97%
With dicyclohexyl-carbodiimide In 1,4-dioxane for 1h; Ambient temperature;	96%

: 59565-09-2
2-(vinyloxy)ethyl isothiocyanate

: 79-08-3
bromoacetic acid

: 137914-53-5
2-<1-(bromoacetoxy)ethoxy>ethyl isothiocyanate

Conditions

Conditions	Yield
at 30 - 45℃; for 0.0833333h; Mechanism; influence of water;	100%
at 30 - 45℃; for 0.0833333h;	100%

: 65253-04-5
(-)-8-phenylmenthol

: 79-08-3
bromoacetic acid

: 80595-59-1
bromoacetic acid (-)-8-phenylmenthol ester

Conditions

Conditions	Yield
With dmap; dicyclohexyl-carbodiimide In dichloromethane for 3h;	100%
With toluene-4-sulfonic acid In benzene for 11h; Heating;	95%
With 0,2,4-dichlorophenyl-0-methylisopropylamidothiophosphate; dicyclohexyl-carbodiimide	80%
With dmap; dicyclohexyl-carbodiimide In dichloromethane for 14h; Ambient temperature;	77%
With toluene-4-sulfonic acid In benzene for 16h; Heating;

: 87573-96-4
N-phenyl-2-thiocyanato-1-pyrrole

: 79-08-3
bromoacetic acid

A: 87574-05-8
N-phenyl-2-pyrrolylthioacetic acid

B: 87574-04-7
N-(2-methoxycarbonylphenyl)-2-methylthiopyrrole

Conditions

Conditions	Yield
With potassium hydroxide In methanol; water for 2h;	A 100% B n/a

...Expand

: 112-53-8
1-dodecyl alcohol

: 79-08-3
bromoacetic acid

: 3674-07-5
dodecyl bromoacetate

Conditions

Conditions	Yield
With 2,6-di-tert-butyl-4-methyl-phenol; toluene-4-sulfonic acid In toluene for 7h; Reflux;	100%
With toluene-4-sulfonic acid; 1-octyl-3-methylimidazolium tetrafluoroborate at 80℃; for 1h;	98%
With toluene-4-sulfonic acid In 5,5-dimethyl-1,3-cyclohexadiene	95%

: 79-08-3
bromoacetic acid

: 18523-48-3
2-azidoacetic acid

Conditions

Conditions	Yield
With sodium azide In water	100%
With sodium azide In water at 20℃;	99%
With sodium azide In water at 20℃; for 48h;	98%

: 108-30-5
succinic acid anhydride

: 5036-48-6
3-(1H-imidazol-1-yl)propan-1-amine

: 79-08-3
bromoacetic acid

: N-carboxymethyl-N-(3-imidazol-1-yl-propyl)-succinamic acid

Conditions

Conditions	Yield
Multistep reaction;	100%

...Expand

: 1155-64-2
N6-[(benzyloxy)carbonyl]-L-lysine

: 79-08-3
bromoacetic acid

: 113231-04-2
Nα,Nα-bis(carboxymethyl)-Nε-(benzyloxycarbonyl)-L-lysine

Conditions

Conditions	Yield
With sodium hydroxide at 0 - 50℃;	100%
With sodium hydroxide at 0 - 50℃;	93%
With sodium hydroxide In water at 0 - 50℃;	92%

: 24233-81-6
octaethylene glycol monodecyl ether

: 79-08-3
bromoacetic acid

: C28H56O11

Conditions

Conditions	Yield
With sodium hydride In tetrahydrofuran at 60℃; for 12h;	100%

: 584-02-1
2-pentanol

: 79-08-3
bromoacetic acid

: 189955-91-7
2-(pentan-3-yloxy)acetic acid

Conditions

Conditions	Yield
With potassium hydride at 60℃; for 20h;	100%
Stage #1: 2-pentanol With sodium hydride; potassium iodide In tetrahydrofuran at 0℃; for 0.25h; Inert atmosphere; Stage #2: bromoacetic acid In tetrahydrofuran for 24h; Inert atmosphere; Reflux;	68%

: 4-bromo-2-ethylbenzene-1-sulfonyl chloride

: 79-08-3
bromoacetic acid

: 1227370-62-8
4-bromo-2-ethyl-1-methanesulfonyl-benzene

Conditions

Conditions	Yield
Stage #1: 4-bromo-2-ethylbenzene-1-sulfonyl chloride With sodium hydrogencarbonate; sodium sulfite In 1,4-dioxane; water at 70℃; for 1h; Stage #2: bromoacetic acid In 1,4-dioxane; water at 100℃; Stage #3: With sodium hydroxide In 1,4-dioxane; water at 90℃;	100%

: 1227392-53-1
C28H40O7

: 79-08-3
bromoacetic acid

: 1227391-77-6
C30H42O9

Conditions

Conditions	Yield
Stage #1: C28H40O7 With sodium hydride In tetrahydrofuran for 2h; Inert atmosphere; Stage #2: bromoacetic acid In tetrahydrofuran Stage #3: With hydrogenchloride In water pH=1;	100%

: 1417917-61-3
5-fluorospiro[indene-2,4‘-piperidin]-1(3H)-one

: 79-08-3
bromoacetic acid

: 1419956-01-6
2-(5-fluoro-1-oxo-1,3-dihydrospiro[indene-2,4'-piperidine]-1'-yl)acetic acid

Conditions

Conditions	Yield
With triethylamine In acetonitrile at 80℃; for 3h;	100%

: N,N-dibutyl-4-(5-mercapto-1,3,4-oxadiazol-2-yl)benzenesulfonamide

: 79-08-3
bromoacetic acid

: 2-((5-(4-(N,N-dibutylsulfamoyl)phenyl)-1,3,4-oxadiazol-2-yl)thio)acetic acid

Conditions

Conditions	Yield
With 4-methyl-morpholine In ethanol at 20℃; for 20h;	100%

: 79-08-3
bromoacetic acid

: 100-46-9
benzylamine

: 213615-03-3
C27H29N3O4

Conditions

Conditions	Yield
Stage #1: bromoacetic acid With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 1h; Stage #2: benzylamine In dichloromethane; N,N-dimethyl-formamide at 20℃; for 0.5h; Stage #3: bromoacetic acid; benzylamine Further stages;	100%

: 79-08-3
bromoacetic acid

: 100-46-9
benzylamine

: 1583306-61-9
C36H38N4O5

Conditions

Conditions	Yield
Stage #1: bromoacetic acid With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 1h; Stage #2: benzylamine In dichloromethane; N,N-dimethyl-formamide at 20℃; for 0.5h; Stage #3: bromoacetic acid; benzylamine Further stages;	100%
Stage #1: bromoacetic acid With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 1h; Stage #2: benzylamine In N,N-dimethyl-formamide at 20℃; for 40h; Stage #3: bromoacetic acid; benzylamine Further stages;	100%

: potassium cyanide

: 79-08-3
bromoacetic acid

: 372-09-8
cyanoacetic acid

Conditions

Conditions	Yield
With sodium hydrogencarbonate In water at 20 - 80℃; for 16h;	100%

: Fmoc-Lys(N-4- methoxytrityl)-2-chlorotrityl-Wang resin

: 2-[2-[2-[[2-[2-[2-[[(4S)-5-tert-butoxy-4-[10-(4-tert-butoxycarbonylphenoxy)decanoylamino]-5-oxo-pentanoyl]amino]ethoxy]ethoxy]-acetyl]amino]ethoxy]ethoxy]acetic acid

: 79-08-3
bromoacetic acid

: 4-[10-[[(1S)-4-[2-[2-[2-[2-[2-[2-[[(5S)-5-[(2-bromoacetyl)amino]-5-carboxypentyl]amino]-2-oxoethoxy]ethoxy]ethylamino]-2-oxoethoxy]ethoxy]ethylamino]-1-carboxy-4-oxobutyl]amino]-10-oxodecoxy]benzoic acid

Conditions

Conditions	Yield
Stage #1: Wang-Fmoc-Lys(Mtt)-OH resin With 1,1,1,3',3',3'-hexafluoro-propanol In dichloromethane Wang-Fmoc-Lys(Mtt)-OH resin; Stage #2: 2-[2-[2-[[2-[2-[2-[[(4S)-5-tert-butoxy-4-[10-(4-tert-butoxycarbonylphenoxy)decanoylamino]-5-oxo-pentanoyl]amino]ethoxy]ethoxy]-acetyl]amino]ethoxy]ethoxy]acetic acid With N-[(6-chlorobenzotriazol-1-yl)oxy-(dimethylamino)methylene]-dimethyl-ammonium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide Wang-Fmoc-Lys(Mtt)-OH resin; Stage #3: bromoacetic acid Further stages;	100%

Yield

Stage #1: Wang-Fmoc-Lys(Mtt)-OH resin With 1,1,1,3',3',3'-hexafluoro-propanol In dichloromethane Wang-Fmoc-Lys(Mtt)-OH resin;
Stage #2: 2-[2-[2-[[2-[2-[2-[[(4S)-5-tert-butoxy-4-[10-(4-tert-butoxycarbonylphenoxy)decanoylamino]-5-oxo-pentanoyl]amino]ethoxy]ethoxy]-acetyl]amino]ethoxy]ethoxy]acetic acid With N-[(6-chlorobenzotriazol-1-yl)oxy-(dimethylamino)methylene]-dimethyl-ammonium tetrafluoroborate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide Wang-Fmoc-Lys(Mtt)-OH resin;
Stage #3: bromoacetic acid Further stages;

100%

...Expand

: 79-08-3
bromoacetic acid

: 100-46-9
benzylamine

: C28H30N2O4

Conditions

Conditions	Yield
Stage #1: bromoacetic acid With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 1h; Stage #2: benzylamine In N,N-dimethyl-formamide at 20℃; for 40h; Stage #3: bromoacetic acid; benzylamine Further stages;	100%

: 79-08-3
bromoacetic acid

: 100-46-9
benzylamine

: 1608499-32-6
C45H47N5O6

Conditions

Conditions	Yield
Stage #1: bromoacetic acid With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 1h; Stage #2: benzylamine In N,N-dimethyl-formamide at 20℃; for 40h; Stage #3: bromoacetic acid; benzylamine Further stages;	100%

: 79-08-3
bromoacetic acid

: 109-85-3
2-methoxyethylamine

: 100-46-9
benzylamine

: C28H38N4O7

Conditions

Conditions	Yield
Stage #1: bromoacetic acid With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 1h; Stage #2: benzylamine In N,N-dimethyl-formamide at 20℃; for 40h; Stage #3: bromoacetic acid; 2-methoxyethylamine; benzylamine Further stages;	100%

...Expand

: 79-08-3
bromoacetic acid

: 109-85-3
2-methoxyethylamine

: 100-46-9
benzylamine

: C42H56N6O10

Conditions

Conditions	Yield
Stage #1: bromoacetic acid With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 1h; Stage #2: benzylamine In N,N-dimethyl-formamide at 20℃; for 40h; Stage #3: bromoacetic acid; 2-methoxyethylamine; benzylamine Further stages;	100%

...Expand

: 79-08-3
bromoacetic acid

: 109-85-3
2-methoxyethylamine

: 100-46-9
benzylamine

: C19H29N3O6

Conditions

Conditions	Yield
Stage #1: bromoacetic acid With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 1h; Stage #2: benzylamine In N,N-dimethyl-formamide at 20℃; for 40h; Stage #3: bromoacetic acid; 2-methoxyethylamine Further stages;	100%

...Expand

: 79-08-3
bromoacetic acid

: N-(2-aminoethyl)-2,3-bis(benzyloxy)benzamide

: C75H74N6O13

Conditions

Conditions	Yield
Stage #1: bromoacetic acid With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 1h; Stage #2: N-(2-aminoethyl)-2,3-bis(benzyloxy)benzamide In dichloromethane at 20℃; for 1h; Stage #3: bromoacetic acid With diisopropyl-carbodiimide In N,N-dimethyl-formamide at 20℃; for 1h;	100%

: 107-10-8
propylamine

: 79-08-3
bromoacetic acid

: 100-46-9
benzylamine

: C42H56N6O7

Conditions

Conditions	Yield
Stage #1: bromoacetic acid With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 1h; Stage #2: propylamine In N,N-dimethyl-formamide at 20℃; for 0.666667h; Stage #3: bromoacetic acid; benzylamine Further stages;	100%

...Expand

: 110-58-7
1-pentanamine

: 79-08-3
bromoacetic acid

: 100-46-9
benzylamine

: C48H68N6O7

Conditions

Conditions	Yield
Stage #1: bromoacetic acid With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 1h; Stage #2: n-Pentylamine In N,N-dimethyl-formamide at 20℃; for 0.666667h; Stage #3: bromoacetic acid; benzylamine Further stages;	100%

...Expand

: 111-68-2
1-Heptylamine

: 79-08-3
bromoacetic acid

: C54H104N6O7

Conditions

Conditions	Yield
Stage #1: bromoacetic acid With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 1h; Stage #2: 1-Heptylamine In N,N-dimethyl-formamide at 20℃; for 0.666667h; Stage #3: bromoacetic acid Further stages;	100%

Bromoacetic acid Specification

The Bromoacetic acid, with the CAS registry number 79-08-3, is also known as Acide bromacetique. It belongs to the product categories of Pharmaceutical Intermediates; Aliphatics; Carboxylic Acids; Acid Based Bromo Compounds; omega-Bromocarboxylic Acids; omega-Functional Alkanols, Carboxylic Acids, Amines & Halides; Carboxylic Acids; 500 Series Drinking Water Methods; Bromo EPA;Chemical Class; Method 552; C1 to C5 Chemical Synthesis; Carbonyl Compounds; A-B Chemical Class; Organic Acids Essential Chemicals; Reagent Grade; Routine Reagents; A-B Alphabetic; Alpha Sort; B; BI - BZ Chemical Class; Bromo; Halogenated; Volatiles/ Semivolatiles; Chemical Synthesis; Organic Acids; Synthetic Reagents. Its EINECS registry number is 201-175-8. This chemical's molecular formula is C₂H₃BrO₂ and molecular weight is 138.95. Its IUPAC name is called 2-bromoacetic acid. What's more, this chemical's classification code is Mutation data. Bromoacetic acid and its esters are widely used building blocks in organic synthesis, for example in pharmaceutical chemistry.

Physical properties of Bromoacetic acid: (1)ACD/LogP: 0.51; (2)ACD/BCF (pH 5.5): 1; (3)ACD/BCF (pH 7.4): 1; (4)ACD/KOC (pH 5.5): 1; (5)ACD/KOC (pH 7.4): 1; (6)#H bond acceptors: 2; (7)#H bond donors: 1; (8)#Freely Rotating Bonds: 1; (9)Index of Refraction: 1.506; (10)Molar Refractivity: 20.611 cm³; (11)Molar Volume: 69.356 cm³; (12)Surface Tension: 51.346 dyne/cm; (13)Density: 2.003 g/cm³; (14)Flash Point: 79.013 °C; (15)Enthalpy of Vaporization: 48.852 kJ/mol; (16)Boiling Point: 207.036 °C at 760 mmHg; (17)Vapour Pressure: 0.093 mmHg at 25°C.

Preparation of Bromoacetic acid: this chemical can be prepared by chloroactic acid and hydrogen.

ClCH₃COOH+HBr→BrCH₂COOH+HCl

When you are using this chemical, please be cautious about it as the following:
This chemical may cause inflammation to the skin or other mucous membranes. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. Whenever you will contact it, please wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell seek medical advice immediately (show the label where possible).

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C(C(=O)O)Br
(2)InChI: InChI=1S/C2H3BrO2/c3-1-2(4)5/h1H2,(H,4,5)
(3)InChIKey: KDPAWGWELVVRCH-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD	intravenous	> 24mg/kg (24mg/kg)	CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE BEHAVIORAL: ATAXIA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Acta Pharmacologica et Toxicologica. Vol. 11, Pg. 33, 1955.
dog	LD	oral	> 48mg/kg (48mg/kg)	BEHAVIORAL: ATAXIA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: NAUSEA OR VOMITING	Acta Pharmacologica et Toxicologica. Vol. 11, Pg. 33, 1955.
guinea pig	LDLo	skin	500mg/kg (500mg/kg)		National Technical Information Service. Vol. OTS0555280,
mouse	LD50	intraperitoneal	66mg/kg (66mg/kg)	LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Journal of the National Cancer Institute. Vol. 31, Pg. 297, 1963.
mouse	LD50	oral	100mg/kg (100mg/kg)		United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-0391-1149,
rabbit	LD50	skin	59900ug/kg (59.9mg/kg)		National Technical Information Service. Vol. OTS0555280,
rabbit	LDLo	intravenous	45mg/kg (45mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: REGIDITY LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 160, Pg. 551, 1931.
rat	LCLo	inhalation	114gm/m³/30M (114000mg/m³)		Russian Pharmacology and Toxicology Vol. 41, Pg. 113, 1978.
rat	LD50	intraperitoneal	50mg/kg (50mg/kg)		Russian Pharmacology and Toxicology Vol. 41, Pg. 113, 1978.
rat	LD50	oral	50mg/kg (50mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: REGIDITY	National Technical Information Service. Vol. OTS0555280,
rat	LD50	skin	100mg/kg (100mg/kg)		United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-0191-1149S,

Product Name

Bromoacetic acid

Synthetic route

Bromoacetic acid Specification

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