Epichlorohydrin supplier | CasNO.106-89-8

Name
1-Chloro-2,3-epoxypropane
EINECS 203-439-8
CAS No. 106-89-8
Article Data190
CAS DataBase
Density 1.205 g/cm³
Solubility 6 g/100 mL (10 °C) in water
Melting Point -57 °C
Formula C₃H₅ClO
Boiling Point 116.1 °C at 760 mmHg
Molecular Weight 92.5251
Flash Point 33.9 °C
Transport Information UN 2023 6.1/PG 2
Appearance clear, colorless
Safety 53-45
Risk Codes 45-10-23/24/25-34-43
Molecular Structure
Hazard Symbols T
Synonyms Oxirane,(chloromethyl)- (9CI);Propane, 1-chloro-2,3-epoxy- (6CI,8CI);(Chloromethyl)ethylene oxide;(Chloromethyl)oxirane;(RS)-Epichlorhydrin;1,2-Epoxy-3-chloropropane;1-Chloro-2,3-epoxypropane;2,3-Epoxypropyl chloride;2-(Chloromethyl)oxirane;3-Chloro-1,2-epoxypropane;3-Chloro-1,2-propylene oxide;3-Chloropropene-1,2-oxide;3-Chloropropylene oxide;Chloropropylene oxide;Glycerol epichlorohydrin;Glycidyl chloride;J 006;NSC 6747;dl-a-Epichlorohydrin;a-Epichlorohydrin;g-Chloropropylene oxide;
PSA 12.53000
LogP 0.62400

Synthetic route

: 107-05-1
3-chloroprop-1-ene

: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
With Cumene hydroperoxide at 60 - 120℃; under 7500.75 Torr; Temperature; Pressure;	99%
With Cumene hydroperoxide at 60 - 120℃; under 7500.75 Torr; Temperature; Pressure;	98%
With 1-phenylethyl hydroperoxide In ethylbenzene at 30 - 50℃; under 750.075 Torr; Pressure; Temperature; Reagent/catalyst;	98%

: 96-23-1
1,3-Dichloro-2-propanol

: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
With resin IRA-440 In dichloromethane for 24h; Ambient temperature;	98%
With strong basic ion-exchange resin IRA 440 In dichloromethane for 24h; Product distribution; Ambient temperature; other basic ion-exchange resins; other glycerol dihalohydrins; other solvents and time;	98%
With calcium hydroxide inactive form;

: 35952-61-5
(C4H9)3SnOCH(CH2Cl)2

A: 1461-22-9
tributyltin chloride

B: 78-95-5
chloroacetone

C: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
63% decompn. at 210°C (1 h);	A n/a B 5% C 95%

...Expand

: 83682-72-8
γ,γ-dichloropropanol

: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
With sodium hydroxide at 20℃; Temperature;	94.1%

: 107-05-1
3-chloroprop-1-ene

A: 4151-97-7
1-chloro-3-methoxypropan-2-ol

B: 96-24-2
3-monochloro-1,2-propanediol

C: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
With dihydrogen peroxide; TS-1 In methanol; water; 1,2-dichloro-benzene at 25 - 40℃; for 1h; Product distribution / selectivity;	A n/a B n/a C 94%

...Expand

: 616-23-9
2,3-Dichloro-1-propanol

: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
With water; sodium hydroxide at 50℃; for 0.00833333h; Time; Temperature; Concentration;	92.4%
With potassium hydroxide

: 556-52-5
oxiranyl-methanol

: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
With 1-chloro-1-(dimethylamino)-2-methyl-1-propene In dichloromethane at 0 - 20℃; Inert atmosphere;	85%

: 96-23-1
1,3-Dichloro-2-propanol

A: 78-95-5
chloroacetone

B: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
With HT4-c823 In water at 149.84℃; under 750.075 Torr; for 0.5h; Catalytic behavior; Reagent/catalyst; Temperature; Flow reactor; chemoselective reaction;	A 18.9% B 80.5%

: 102129-99-7
(R,S)-2-hydroxy-3-chloropropyl p-toluenesulfonate

: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
With sodium ethane-1,2-diolate In ethylene glycol at 20℃; for 0.25h;	79%

: 589-96-8
(+/-)-1-Acetoxy-2,3-dichloropropane

: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
With calcium hydroxide 1.) H2O, r.t., 1 h, 2.) hexane, 6 h;	77%

: 56-81-5
glycerol

: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
Stage #1: glycerol With hydrogenchloride; Adipic acid In water at 120℃; for 8h; Stage #2: With calcium hydroxide	67.5%
With phosphorus trichloride
With hydrogenchloride anschl. mit Aetzkali;

: 4540-44-7
1-bromo-3-chloro-propan-2-ol

: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
With sodium ethane-1,2-diolate In ethylene glycol at 20℃; for 0.25h;	58%
With potassium hydroxide levorotatory form;

: 616-23-9
2,3-Dichloro-1-propanol

A: 57090-45-6
(2R)-3-chloro-1,2-propanediol

B: 60827-45-4
(S)-3-chloropropan-1,2-diol

C: (S)-1,3-dichloro-1-propanol

D: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
With epoxide hydrolase from Agrobacterium radiobacter AD1; halohydrin dehalogenase from Agrobacterium radiobacter AD1; Tris-SO4 buffer In water at 30℃; for 20h; pH=7.5; kinetic resolution; Further byproducts given;	A n/a B n/a C 49.5% D n/a

...Expand

: 7722-84-1
dihydrogen peroxide

: 107-05-1
3-chloroprop-1-ene

A: 7732-18-5
water

B: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
With titanium-containing zeolite In methanol at 35℃; Mechanism; Solvent;	A n/a B 29.8%

...Expand

: 107-05-1
3-chloroprop-1-ene

A: 100-52-7
benzaldehyde

B: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
With molybdenum blue; dihydrogen peroxide; bis(tri-n-butyltin)oxide In chloroform at 25℃; for 10h;	A 1% B 48 % Turnov.

: 96-23-1
1,3-Dichloro-2-propanol

A: 56-81-5
glycerol

B: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
With potassium hydroxide

: 3674-10-0
1,3-dichloro-2-acetoxypropane

A: 75-36-5
acetyl chloride

B: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
beim Stehenlassen;

: 79-21-0
peracetic acid

: 107-05-1
3-chloroprop-1-ene

: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
With catalysts

(+-)-2,3-dichloro-propan-1-ol: (+-)-2,3-dichloro-propan-1-ol

: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
With calcium hydroxide
With sodium hydroxide Herstellung eines mit Chlor-36 markierten Praeparats;

: 4540-44-7
1-bromo-3-chloro-propan-2-ol

potash: potash

A: 10035-10-6, 12258-64-9
hydrogen bromide

B: 106-89-8
epichlorohydrin

...Expand

: 96-23-1
1,3-Dichloro-2-propanol

KOH: KOH

: 106-89-8
epichlorohydrin

: 616-23-9
2,3-Dichloro-1-propanol

potash: potash

: 106-89-8
epichlorohydrin

: 616-23-9
2,3-Dichloro-1-propanol

: 7732-18-5
water

sodium hydroxide: sodium hydroxide

: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
at 0℃;
at 0℃; Geschwindigkeit;
at 25℃; Geschwindigkeit;

...Expand

: 26484-95-7
1-chloro-3-iodopropan-2-ol

KOH-solution: KOH-solution

A: 10034-85-2
hydrogen iodide

B: 106-89-8
epichlorohydrin

...Expand

: 60-29-7
diethyl ether

: 96-23-1
1,3-Dichloro-2-propanol

: 7732-18-5
water

sodium amalgam: sodium amalgam

A: 107-18-6
allyl alcohol

B: 106-89-8
epichlorohydrin

...Expand

: 60-29-7
diethyl ether

: 96-23-1
1,3-Dichloro-2-propanol

sodium: sodium

A: 187737-37-7
propene

B: 107-18-6
allyl alcohol

C: 106-89-8
epichlorohydrin

...Expand

: 64-17-5
ethanol

: 96-23-1
1,3-Dichloro-2-propanol

powdered NaOH: powdered NaOH

A: 4043-59-8
1,3-diethoxy-isopropanol

B: 106-89-8
epichlorohydrin

C glycidethyl ether: glycidethyl ether

...Expand

: 3-hydroxy-benzoic acid-(2-chloro-1-chloromethyl-ethyl ester)

potash: potash

: 106-89-8
epichlorohydrin

Conditions

Conditions	Yield
at 100℃;

: 110-91-8
morpholine

: 106-89-8
epichlorohydrin

: 40893-69-4
1-chloro-3-(4-morpholinyl)-2-propanol

Conditions

Conditions	Yield
In ethanol for 24h; Heating;	100%
With zinc(II) chloride In water at 60℃; for 8h; regioselective reaction;	96%
In water at 0 - 5℃; for 4h;	92%

: 120-47-8
Ethyl 4-hydroxybenzoate

: 106-89-8
epichlorohydrin

: 50625-94-0
ethyl 4-(glycidyloxy)benzoate

Conditions

Conditions	Yield
With sodium carbonate; N,N-dimethyl-formamide at 80℃; for 12h; Inert atmosphere;	100%
With potassium carbonate In acetone for 20h; Heating;
With potassium carbonate In butanone Heating;
With potassium carbonate In acetone; toluene	13.5 gm (61%)
With sodium hydroxide

: 64-19-7
acetic acid

: 106-89-8
epichlorohydrin

: 24573-30-6
3-chloro-2-hydroxy-1-propyl acetate

Conditions

Conditions	Yield
With iron(III) chloride at 20 - 70℃; for 24.1667h;	100%
With tin(IV)tetraphenylporphyrinato trifluoromethanesulfonate for 0.666667h; Heating;	99%
With cerium(IV) triflate at 80℃; for 0.0833333h;	93%

: 106-89-8
epichlorohydrin

: 108-95-2
phenol

: 122-60-1
Phenyl glycidyl ether

Conditions

Conditions	Yield
Stage #1: phenol With sodium hydroxide In water at 25℃; for 0.666667h; Stage #2: epichlorohydrin In water at 30 - 35℃; for 16h;	100%
With n-Bu4NOSO2OCH2CHOHCH3; potassium carbonate at 75 - 80℃; for 1.5h;	91%
With n-BuNOSO2OCH2CHOHCH3; potassium carbonate at 75 - 80℃; for 1.5h; other aryl alcohols, var. phase transfer catalysts, var. reaction time;	91%

: 106-89-8
epichlorohydrin

: 4540-44-7
1-bromo-3-chloro-propan-2-ol

Conditions

Conditions	Yield
With hydrogen bromide at -60℃; for 16h;	100%
With dimethylbromosulphonium bromide In acetonitrile at 20℃; for 0.333333h;	98%
With ammonium cerium(IV) nitrate; tetrabutylammomium bromide In tert-butyl alcohol for 1.5h; Ambient temperature;	96%

: 106-89-8
epichlorohydrin

: 96-23-1
1,3-Dichloro-2-propanol

Conditions

Conditions	Yield
With hydrogenchloride In dichloromethane for 12h; Ambient temperature;	100%
With hydrogenchloride In water	100%
With chloro-trimethyl-silane; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate at 20℃; for 1h; ring opening reaction;	99%

: 106-89-8
epichlorohydrin

: 19030-86-5
bis(3-chloro-2-hydroxypropyl)sulfide

Conditions

Conditions	Yield
With hydrogenchloride; sodium hydrogen sulfide monohydrate; sodium hydroxide In methanol; water at 6℃;	100%
With hydrogen sulfide; tetrabutylammomium bromide In toluene at 20 - 25℃; Solvent; Temperature; Reagent/catalyst;	96%
With hydrogen sulfide

: 108-18-9
diisopropylamine

: 106-89-8
epichlorohydrin

: 55211-97-7
1-Chlor-2-hydroxy-3-diisopropylamino-methyl-propan

Conditions

Conditions	Yield
In ethanol for 24h; Heating;	100%
In water

: 62-53-3
aniline

: 106-89-8
epichlorohydrin

: 76226-32-9, 15949-12-9
N-(3-chloro-2-hydroxypropyl)aniline

Conditions

Conditions	Yield
With lithium bromide at 20℃; for 5h;	100%
With Ni2+-metallodendrimer grafted on mesoporous polymethacrylate based Sepabeads EB-EP-400 In neat (no solvent) at 20℃; for 0.5h; Reagent/catalyst; Solvent; Green chemistry; regioselective reaction;	97%
With BiCl6(3-)2C4H10N2ClH3H(1+)H2O at 20℃; for 0.116667h; Neat (no solvent); regioselective reaction;	96%

: 123-75-1
pyrrolidine

: 106-89-8
epichlorohydrin

: 58759-70-9
1-chloro-3-(1-pyrrolidinyl)-2-propanol

Conditions

Conditions	Yield
In ethanol for 24h; Heating;	100%
In ethanol at 20℃; under 2585.81 Torr; for 0.0166667h; microwave irradiation;	65%

: 109-83-1
(2-hydroxyethyl)(methyl)amine

: 106-89-8
epichlorohydrin

: 63125-83-7
1-Chlor-2-hydroxy-3-(N-methyl-N-2-hydroxyethyl)-amino-propan

Conditions

Conditions	Yield
at 40 - 70℃;	100%
In water at 13 - 34℃; for 1.41667h;
In isopropyl alcohol

: 2380-94-1
1H-indol-4-ol

: 106-89-8
epichlorohydrin

: 35308-87-3
4-(oxiranylmethoxy)-1H-indole

Conditions

Conditions	Yield
With potassium hydroxide In dimethyl sulfoxide at 45℃; for 4h;	100%
Stage #1: 1H-indol-4-ol; epichlorohydrin With potassium hydroxide In dimethyl sulfoxide at 45℃; for 4h; Stage #2: With ammonium chloride In water	99%
With potassium hydroxide In dimethyl sulfoxide at 45℃; for 4h;	99%

: 5373-72-8
4-phenyl-Δ2-1,2,4-triazoline-5-thione

: 106-89-8
epichlorohydrin

: 134619-57-1
4-phenyl-3-(1-chloro-2-hydroxypropylthio)-1,2,4-triazole

Conditions

Conditions	Yield
In ethanol at 20℃; for 5h;	100%

: 112-92-5
1-octadecanol

: 106-89-8
epichlorohydrin

: 16245-97-9
octadecyl glycidyl ether

Conditions

Conditions	Yield
With sodium hydroxide; Aliquat 336 In cyclohexane Heating;	100%
With sodium hydroxide; Aliquat 336 In cyclohexane Heating;	99%
With sodium hydroxide; Aliquat 336 In cyclohexane for 4h; Heating;	99%

: 7677-24-9
trimethylsilyl cyanide

: 106-89-8
epichlorohydrin

: 81091-27-2
4-chloro-3-trimethylsiloxybutyronitrile

Conditions

Conditions	Yield
With erbium(III) triflate at 0 - 20℃; for 0.166667h; regioselective reaction;	100%
ytterbium cyanide In tetrahydrofuran at 25℃; for 0.3h;	91%

: 124-38-9
carbon dioxide

: 106-89-8
epichlorohydrin

: 2463-45-8
4-chloromethyl-[1,3]dioxolan-2-one

Conditions

Conditions	Yield
With dmap; CrTTPCl at 60℃; under 37751.8 - 40337.5 Torr; for 18h;	100%
With triphenylphosphine; phenol at 120℃; under 30002.4 Torr; for 14h;	100%
With triethylamine; binaphthyldiamino Zn(II) salen-type compex In dichloromethane at 100℃; under 25858.1 Torr;	100%

: 1502-03-0
Cyclododecylamine

: 106-89-8
epichlorohydrin

: 1-Chloro-3-cyclododecylamino-propan-2-ol

Conditions

Conditions	Yield
In ethanol for 24h; Heating;	100%

: 16966-40-8
isoselenocyanatotrimethylsilane

: 106-89-8
epichlorohydrin

: 128256-05-3
3-Chloro-2-trimethylsiloxypropyl selenocyanate

Conditions

Conditions	Yield
potassium selenocyanate In hexane at 40℃; for 24h;	100%

: 5452-37-9
cyclooctylamine

: 106-89-8
epichlorohydrin

: 1-Chloro-3-cyclooctylamino-propan-2-ol

Conditions

Conditions	Yield
In ethanol for 24h; Heating;	100%

: 15598-34-2
pyridinium perchlorate

: 106-89-8
epichlorohydrin

: 1-(2-hydroxy-3-chloropropyl)pyridinium perchlorate

Conditions

Conditions	Yield
With pyridine In ethanol for 3h; Product distribution; Heating; further cycloimmonium salts;	100%
With pyridine In ethanol for 3h; Heating;	100%

: 52827-74-4
4-methylpyridinium perchlorate

: 106-89-8
epichlorohydrin

: 1-(2-hydroxy-3-chloropropyl)-4-methylpyridinium perchlorate

Conditions

Conditions	Yield
With picoline for 1h; Heating;	100%

: 102-92-1
cinnamoyl chloride

: 106-89-8
epichlorohydrin

: 157140-94-8
1,3-dichloro-2-propyl cinnamate

Conditions

Conditions	Yield
With yttrium(III) chloride In dichloromethane for 36h; Ambient temperature;	100%

: 85095-40-5
N-(1-chlorohexafluoro-1-methylethyl)benzenesulfinimidoyl chloride

: 106-89-8
epichlorohydrin

: 91363-16-5
C12H10Cl3F6NOS

Conditions

Conditions	Yield
In tetrachloromethane at 25℃; for 48h;	100%

: 85095-41-6
N-(2-chlorohexafluoroisopropyl)-p-toluenesulfinimidoyl chloride

: 106-89-8
epichlorohydrin

: 91363-17-6
C13H12Cl3F6NOS

Conditions

Conditions	Yield
In tetrachloromethane at 25℃; for 48h;	100%

: 101-83-7
N-cyclohexyl-cyclohexanamine

: 106-89-8
epichlorohydrin

: 150389-77-8
1-Chloro-3-dicyclohexylamino-propan-2-ol

Conditions

Conditions	Yield
In ethanol for 24h; Heating;	100%

: 151073-99-3
(2-trimethylsilylprop-2-en-1-yl)tributylstannane

: 106-89-8
epichlorohydrin

: 1-Chloro-5-(trimethylsilyl)-5-hexen-2-ol

Conditions

Conditions	Yield
With ethylaluminum dichloride In dichloromethane at -78℃; for 19h;	100%

: 1745-81-9
2-Allylphenol

: 106-89-8
epichlorohydrin

: 49716-04-3
1-(2-allyl-phenoxy)-3-chloro-propan-2-ol

Conditions

Conditions	Yield
With pyridine In chloroform; water; phenol	100%
With piperidine Heating;

: 106-89-8
epichlorohydrin

: 1131-60-8
p-cyclohexylphenol

: 67006-99-9
2-[(4-cyclohexylphenoxy)methyl]oxirane

Conditions

Conditions	Yield
With sodium hydroxide for 1h; Reflux;	100%
With sodium In isopropyl alcohol 1.) 10 min., reflux, 2.) 16 h., room temp.;

: 106-89-8
epichlorohydrin

: 36636-44-9
bis(2-bromo-2-chloropropyl)(2-bromo-3-chloropropyl)phosphonate

Conditions

Conditions	Yield
With phosphorus tribromide at 0 - 40℃;	100%

: 106-89-8
epichlorohydrin

: 108-95-2
phenol

: 140630-45-1
(R)-1-chloro-3-phenoxy-2-propanol

Conditions

Conditions	Yield
With chiral oligo-(salen)Co(OTs) complexes; lutidinium p-toluene sulfonate In acetonitrile at 4℃; for 4h;	100%
With (R,R)-(salen)Co(H2O); 3 A molecular sieve In various solvent(s) at -15℃;	97%
With C57H68N4O8(2-)Co(3+)C7H7O3S(1-); C56H66N2O6(2-)Co(3+)C7H7O3S(1-) In tetrachloromethane at 4 - 20℃; for 6h; stereoselective reaction;	95%
With Co(salen) macrocycles 1(OTs) In tert-butyl methyl ether at 20℃; for 9h; optical yield given as %ee; enantioselective reaction;	91%
With Co(salen) macrocycles 1(OTs) In tert-butyl methyl ether at 20℃; Kinetics; enantioselective reaction;

Epichlorohydrin Chemical Properties

Product Name: Epichlorohydrin (CAS NO.106-89-8)

Molecular Formula: C₃H₅ClO
Molecular Weight: 92.52g/mol
Mol File: 106-89-8.mol
EINECS: 203-439-8
Boiling point: 116.1 °C at 760 mmHg
Storage Temperature: Refrigerator (+4°C) + Flammables area
Flash Point: 33.9 °C
Density: 1.205 g/cm³
Refractive index: n20/D 1.438(lit.)
Stability: Stability Unstable. Flammable - note wide explosion limits and low flash point. Vapours may flow along surfaces to source of ignition. Contact with strong oxidisers may lead to fire. Incompatible with strong acids, strong bases, strong oxidizing agents, metal salts, amines, aluminium, chlorine and a variety of chlorine compounds, most com
Index of Refraction: 1.443
Molar Refractivity: 20.37 cm³
Molar Volume: 76.7 cm³
Surface Tension: 35.6 dyne/cm
Enthalpy of Vaporization: 33.98 kJ/mol
Vapour Pressure: 22 mmHg at 25°C
XLogP3-AA: 0.5
H-Bond Donor: 0
H-Bond Acceptor: 1
Structure Descriptors of Epichlorohydrin (CAS NO.106-89-8):
IUPAC Name: 2-(chloromethyl)oxirane
Canonical SMILES: C1C(O1)CCl
InChI: InChI=1S/C3H5ClO/c4-1-3-2-5-3/h3H,1-2H2
InChIKey: BRLQWZUYTZBJKN-UHFFFAOYSA-N
Product Categories: Chlorepoxypropane (Epichlorohydrin); Organics; Oxiranes; Simple 3-Membered Ring Compounds

Epichlorohydrin Uses

Epichlorohydrin (CAS NO.106-89-8) is a highly reactive compound,it is often used in the production of plastics,glycerol, and elastomers. Epichlorohydrin is a versatile precursor in the synthesis of many organic compounds. Epichlorohydrin is also used in water purification and paper reinforcement,such as in the food industry to manufacture coffee filters,tea bags, and sausage/salami casings.

Epichlorohydrin Production

Epichlorohydrin can be manufactured from allyl chloride in two steps:

Epichlorohydrin Toxicity Data With Reference

1.	skn-rbt 10 mg/24H open	JIHTAB Journal of Industrial Hygiene and Toxicology. 30 (1948),63.
2.	eye-rbt 100 mg/24H MOD	85JCAE Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,769.
3.	dni-hmn:hla 2700 µmol/L	MUREAV Mutation Research. 92 (1982),427.
4.	sce-hmn:lym 10 nmol/L	CARYAB Caryologia. 34 (1981),261.
5.	spm-mus-ihl 5 mg/m3	MUREAV Mutation Research. 85 (1981),287.
6.	orl-mus TDLo:1200 mg/kg (female 6-15D post):TER	JTEHD6 Journal of Toxicology and Environmental Health. 9 (1982),87.
7.	ihl-rat TCLo:50 ppm/6H (male 50D pre):REP	TXAPA9 Toxicology and Applied Pharmacology. 68 (1983),415.
8.	orl-rat TDLo:60 g/kg/81W-I:CAR	GANNA2 Gann. Japanese Journal of Cancer Research. 71 (1980),922.
9.	ihl-rat TCLo:100 ppm/6H/30D-C:CAR	JJIND8 JNCI, Journal of the National Cancer Institute. 65 (1980),751.
10.	ipr-mus TDLo:2400 mg/kg/8W-I:NEO	TXAPA9 Toxicology and Applied Pharmacology. 82 (1986),19.

Epichlorohydrin Consensus Reports

NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2A IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 202.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 11 , 1976,p. 131.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program. Community Right-To-Know List. EPA Extremely Hazardous Substances List. Reported in EPA TSCA Inventory.

Epichlorohydrin Safety Profile

Confirmed carcinogen with experimental carcinogenic data. Poison by ingestion, skin contact, intravenous, and intraperitoneal routes. Moderately toxic by inhalation. An experimental teratogen. Other experimental reproductive effects. Human systemic effects by inhalation: respiratory, nose, and eyes. Human mutation data reported. A skin and eye irritant. A sensitizer. Flammable liquid when exposed to heat or flame. Explosive reaction with aniline. Reaction with trichloroethylene forms the explosive dichloroacetylene. Ignition on contact with potassium tert-butoxide. Violent reaction with sulfuric acid or isopropylamine. Exothermic polymerization on contact with strong acids, caustic alkalies, aluminum, aluminum chloride, iron(III) chloride, or zinc. When heated to decomposition it emits toxic fumes of Cl⁻.
Hazard Codes : T Toxic
Risk Statements :45-10-23/24/25-34-43
R45:May cause cancer.
R10:Flammable.
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
R43:May cause sensitization by skin contact.
Safety Statements :53-45
S53:Avoid exposure - obtain special instructions before use.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2023 6.1/PG 2
WGK Germany: 3

Epichlorohydrin Standards and Recommendations

OSHA PEL: TWA 2 ppm (skin)
ACGIH TLV: TWA 0.5 ppm (skin); Animal Carcinogen
DFG MAK: DFG TRK: Animal Carcinogen, Suspected Human Carcinogen
NIOSH REL: Minimize exposure
DOT Classification: 6.1; Label: Poison

Epichlorohydrin Analytical Methods

For occupational chemical analysis use NIOSH: Epichlorohydrin, 1010.

Epichlorohydrin Specification

Epichlorohydrin , its CAS NO. is 106-89-8, the synonyms are 1-Chloro-2,3-epoxy propane ; 2-(Chloromethyl)oxirane ; 3-Chloro-1,2-epoxypropane .

Product Name

1-Chloro-2,3-epoxypropane

Synthetic route

Epichlorohydrin Chemical Properties

Epichlorohydrin Uses

Epichlorohydrin Production

Epichlorohydrin Toxicity Data With Reference

Epichlorohydrin Consensus Reports

Epichlorohydrin Safety Profile

Epichlorohydrin Standards and Recommendations

Epichlorohydrin Analytical Methods

Epichlorohydrin Specification

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