Isopropyl ether supplier | CasNO.108-20-3

Name
2-Isopropoxypropane
EINECS 203-560-6
CAS No. 108-20-3
Article Data260
CAS DataBase
Density 0.758 g/cm³
Solubility 9 g/L (20 °C) in water
Melting Point -85.5 °C
Formula C₆H₁₄O
Boiling Point 68.3 °C at 760 mmHg
Molecular Weight 102.177
Flash Point −29°F
Transport Information UN 1159 3/PG 2
Appearance colourless liquid
Safety 9-16-29-33
Risk Codes 11-19-66-67
Molecular Structure
Hazard Symbols F
Synonyms Isopropylether (8CI);2,2'-Oxybispropane;2-Isopropoxypropane;Bis(isopropyl) ether;Di-1-methylethyl ether;Diisopropyl ether;Diisopropyl oxide;iso-Propyl ether;Propane, 2,2'-oxybis-;
PSA 9.23000
LogP 1.81980

Synthetic route

: 187737-37-7
propene

: 64-19-7
acetic acid

A: 108-20-3
di-isopropyl ether

B: 108-21-4
Isopropyl acetate

C: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
With water; cesium nitrate; tungstophosphoric acid; water; mixture of, dried, tabletted at 105.6 - 165℃; under 6750.68 Torr; Product distribution / selectivity; Gas phase;	A 2.3% B 94.7% C 2.8%

...Expand

: 769-42-6
1,3-dimethylbarbituric acid

: 67-64-1
acetone

A: 108-20-3
di-isopropyl ether

B: 7358-62-5
1,3-dimethyl-5-isopropylbarbituric acid

C: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
Stage #1: 1,3-dimethylbarbituric acid; acetone Stage #2: With sulfuric acid; hydrogen; platinum on activated charcoal In water under 3878.61 Torr; for 48h;	A n/a B 92% C n/a

...Expand

: 546-68-9
titanium(IV) isopropylate

A: 108-20-3
di-isopropyl ether

B: titanium(IV) oxide

C: 67-63-0
isopropyl alcohol

D: 67-64-1
acetone

Conditions

Conditions	Yield
In gas byproducts: CH3CHCH2; decomposition at a pressure of ca. 0.01 mm of Hg at 550°C; further compound: H2 was obtained with a yield of <0.5%; org. compounds collected in a liquid-N2 trap; NMR; GC; mass spectra;	A 2% B n/a C 87% D 11%

...Expand

: Nd4(μ3-O(i-Pr))2(μ-O(i-Pr))4(O(i-Pr))6(isopropanol)4

A: 6Nd(3+)*5O(2-)*8C3H7O(1-) = Nd6O5(OC3H7)8

B: 108-20-3
di-isopropyl ether

C: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
drying (vac., room temp., 48 h); elem. anal.;	A 80% B n/a C n/a

...Expand

: 67-64-1
acetone

A: 108-11-2
Methyl isobutyl carbinol

B: 108-20-3
di-isopropyl ether

C: 108-10-1
4-methyl-2-pentanone

D: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
With hydrogen; Pd on nickel-silica composite hollow nanospheres at 199.85℃; Product distribution; Further Variations:; Catalysts;	A 1.5% B 8.2% C 5.4% D 75.6%

...Expand

: 67-63-0
isopropyl alcohol

: 100-51-6
benzyl alcohol

A: 108-20-3
di-isopropyl ether

B: 937-54-2
benzyl isopropyl ether

C: 103-50-4
dibenzyl ether

Conditions

Conditions	Yield
With copper acetylacetonate; carbon tetrabromide at 150℃; for 8h; Inert atmosphere; Sealed tube;	A 14% B 65% C 30%
With Cp*Ir(Cl)2(nBu2Im); silver trifluoromethanesulfonate at 110℃; for 12h;	A n/a B 80 %Spectr. C 16 %Spectr.

...Expand

: 67-63-0
isopropyl alcohol

A: 187737-37-7
propene

B: 108-20-3
di-isopropyl ether

Conditions

Conditions	Yield
1-methyl-3-(propyl-3-sulfonyl)imidazolium trifluoromethanesulfonate; CF3O3S(1-)CHF3O3SC7H13N2O3S(1+) at 240 - 260℃; for 4h; Product distribution / selectivity;	A 59% B n/a
sulfated zirconia oxide at 100℃; for 0.0333333h; Rate constant; further catalysts;
aluminum oxide; titanium(IV) oxide at 199.9℃; Product distribution; other temperatures; percent conversion;

: 67-63-0
isopropyl alcohol

: 108-67-8
1,3,5-trimethyl-benzene

A: 108-20-3
di-isopropyl ether

B: 5980-96-1
1-isopropyl-2,4,6-trimethylbenzene

C: 2,4-Diisopropyl-1,3,5-trimethyl-benzene

Conditions

Conditions	Yield
Deloxan catalyst In carbon dioxide at 31.1℃; under 55354.4 Torr;	A 1% B 40% C 5%

...Expand

: 67-63-0
isopropyl alcohol

: 108-20-3
di-isopropyl ether

Conditions

Conditions	Yield
Deloxan ASP 1/7 acid catalyst In carbon dioxide at 200℃; under 150015 Torr;	29%
molecular sieve Rate constant; rate constants for dehydratation at various temperatures;
monoaluminum phosphate at 299.9℃; Rate constant; Thermodynamic data;

: 201230-82-2
carbon monoxide

: 67-63-0
isopropyl alcohol

A: 123-51-3
i-Amyl alcohol

B: 78-83-1
2-methyl-propan-1-ol

C: 108-20-3
di-isopropyl ether

D: 78448-33-6
1-isopropoxy-2-methyl-propane

Conditions

Conditions	Yield
With hydrogen; Cobalt rhodium; iodine at 200℃; under 315025 Torr; for 2h; Product distribution; other promoter, other pressure;	A n/a B 22% C 12% D 9%

...Expand

: 75-30-9
2-iodo-propane

: 108-20-3
di-isopropyl ether

Conditions

Conditions	Yield
With silver(l) oxide

: 187737-37-7
propene

: 108-20-3
di-isopropyl ether

Conditions

Conditions	Yield
With sulfuric acid; water at 110℃;
With water at 150℃; under 51485.6 Torr; in Gegenwart von Ionen-Austauschern;
With water at 150℃; under 29420.3 Torr; in Gegenwart von Ionen-Austauschern;
With water at 150℃; under 29420.3 Torr; in Gegenwart von Ionen-Austauschern;
With water at 150℃; under 51485.6 Torr; in Gegenwart von Ionen-Austauschern;

: 187737-37-7
propene

A: 108-20-3
di-isopropyl ether

B: 67-63-0
isopropyl alcohol

Conditions

Conditions	Yield
With phosphoric acid; water at 165 - 290℃; under 69873.3 - 369960 Torr; in fluessiger oder dampffoermiger Phase;
With sulfuric acid
With water; zeolite ZSM-5 (alumina) at 75 - 380℃; under 11251.1 - 108761 Torr; Industry scale;

: 187737-37-7
propene

: 67-63-0
isopropyl alcohol

: 108-20-3
di-isopropyl ether

Conditions

Conditions	Yield
With sulfuric acid
carbonized cellulose (degree of graphitization 0.63); sulfonated (C/S ratio 74.7) at 110℃; under 37503.8 Torr; for 2h; Product distribution / selectivity;
carbonized glucose; sulfonated at 110℃; under 37503.8 Torr; for 2h; Product distribution / selectivity;
With sulfonated styrene/divinylbenzene co-polymer ion exchange resin at 110℃; under 52476.2 Torr;
With sulfuric acid

: 2973-10-6
diisopropyl sulfate

: 67-63-0
isopropyl alcohol

: 108-20-3
di-isopropyl ether

Conditions

Conditions	Yield

: 120-18-3
naphthalene-2-sulfonate

: 67-63-0
isopropyl alcohol

A: 187737-37-7
propene

B: 108-20-3
di-isopropyl ether

Conditions

Conditions	Yield
Dehydratation;

...Expand

: 67-63-0
isopropyl alcohol

: 98-11-3
benzenesulfonic acid

A: 187737-37-7
propene

B: 108-20-3
di-isopropyl ether

Conditions

Conditions	Yield
Dehydratation;

...Expand

: 187737-37-7
propene

: 71-36-3
butan-1-ol

A: 617-29-8
2-methylhexan-3-ol

B: 108-20-3
di-isopropyl ether

C: 142-96-1
dibutyl ether

D: 6863-58-7
di-2-butyl ether

Conditions

Conditions	Yield
at 251℃; Produkt5:Butyl-sek.-butyl-aether; Produkt6:Butyl-tert.-butyl-aether; Produk7:Isopropyl-sek.-butyl-aether; Produkt8:Isopropylalkohol;
at 251℃; Produkt5:Butyl-sek.-butyl-aether; Produkt6:Butyl-tert.-butyl-aether; Produk7:Isopropyl-sek.-butyl-aether; Produkt8:Isopropylalkohol;

...Expand

: 187737-37-7
propene

A: 108-20-3
di-isopropyl ether

B: 67-63-0
isopropyl alcohol

C: 67-64-1
acetone

Conditions

Conditions	Yield
With water; ferrierite zeolite In gas at 150℃; under 3677.5 Torr; Product distribution; other pressure, other temp., other catalyst;

...Expand

: 6163-66-2
2,2'-oxybis(2-methyl-propane)

: 17009-86-8
protonated diisopropyl ether

A: 108-20-3
di-isopropyl ether

B: Di-tert-butyl-oxonium

Conditions

Conditions	Yield
at 335℃; Thermodynamic data; -ΔGo;

...Expand

: 1118-30-5
propanone diisopropyl acetal

A: 108-20-3
di-isopropyl ether

B: 67-63-0
isopropyl alcohol

C: 67-64-1
acetone

Conditions

Conditions	Yield
With toluene-4-sulfonic acid quantity of toluene-4-sulphonic acid;

...Expand

: 5-(4-benzyloxycarbonylaminophenyl)methyl-2,4-oxazolidinedione

: 108-20-3
di-isopropyl ether

: 258856-39-2
5-(4-aminobenzyl)-2,4-dioxooxazolidine

Conditions

Conditions	Yield
palladium-carbon In ethanol; hexane	100%

: 624-92-0
Dimethyldisulphide

: 108-20-3
di-isopropyl ether

: sodium hydrogensulfite

: 101-79-1
4-amino-4'-chlorodiphenyl ether

: 4-chloro-4'-thiomethyldiphenylether

Conditions

Conditions	Yield
With hydrogenchloride; sodium nitrite In water	100%

...Expand

: 429667-22-1
1-(4-N-cyclohexylcarbamoyl-1,3-thiazol-2-yl)-3-hydroxyazetidine

: 108-20-3
di-isopropyl ether

: 124-63-0
methanesulfonyl chloride

: 429667-24-3
1-(4-N-cyclohexylcarbamoyl-1,3-thiazol-2-yl)-3-methanesulfonyloxyazetidine

Conditions

Conditions	Yield
With triethylamine In dichloromethane	100%

...Expand

: ammonium hexafluorophosphate

: 108-20-3
di-isopropyl ether

: Co(NC5H4C5H2N(C4H3S)C5H4N)2(2+)*2PF6(1-)*4H2O=(Co(NC5H4C5H2N(C4H3S)C5H4N)2)(PF6)2*4H2O

: Co(NC5H4C5H2N(C4H3S)C5H4N)2(3+)*3PF6(1-)*((CH3)2CH)2O*H2O=(Co(NC5H4C5H2N(C4H3S)C5H4N)2)(PF6)3*((CH3)2CH)2O*H2O

Conditions

Conditions	Yield
With bromine In methanol; acetonitrile Co complex dissolved in MeCN; excess of MeOH soln. of Br2 added; 30 min;aq. NH4PF6 added; recrystd. by diffusion of diisopropyl ether vapour into MeCN soln.; elem. anal.;	100%

...Expand

: 1-benzyloxycarbonylmethyl-2-oxo-3-tert-butoxycarbonylamino-5-pivaloyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepine

: 108-20-3
di-isopropyl ether

: 2-oxo-3-tert-butoxycarbonylamino-5-pivaloyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-1-yl-acetic acid

Conditions

Conditions	Yield
palladium-carbon In methanol	99.6%

: 108-20-3
di-isopropyl ether

: 151225-00-2
3-Trichloroacetylamino-5,6,7,8-tetrahydroquinoline

: 151225-01-3
3-Trichloroacetylamino-5,6,7,8-tetrahydroquinoline-1-oxide

Conditions

Conditions	Yield
With 3-chloro-benzenecarboperoxoic acid In dichloromethane	99%

: 211495-76-0
2-(5-amino-1,2,4-thiadiazol-3-yl)-(Z)-2-methoxyiminoacetamide

: 108-20-3
di-isopropyl ether

: 211495-79-3
2-(5-amino-1,2,4-thiadiazol-3-yl)-2(Z)-2-methoxyiminoacetic acid

Conditions

Conditions	Yield
With sodium hydroxide; magnesium sulfate	98.2%

: 108-20-3
di-isopropyl ether

: 150215-26-2
1-(3-isoxazolyl)-3-(methoxycarbonyl)thiourea

: 150215-27-3
2-(5-methoxycarbonylamino-1,2,4-thiadiazol-3-yl)acetaldehyde

Conditions

Conditions	Yield
In methanol	98%

: 3-bromomethyl-7-(2,6-difluorobenzyl)-4,7-dihydro-5-isobutyryl-2-(4-nitrophenyl)-4-oxothieno[ 2,3-b]pyridine

: 108-20-3
di-isopropyl ether

: 103-67-3
benzyl-methyl-amine

: 3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobenzyl)-4,7-dihydro-5-isobutyryl-2-(4-nitrophenyl)-4-oxothieno[2,3-b]pyridine

Conditions

Conditions	Yield
With potassium carbonate; N-ethyl-N,N-diisopropylamine In water; N,N-dimethyl-formamide	97.9%

...Expand

: 108-20-3
di-isopropyl ether

: 2-hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-t-butylaminoethyl)-pyridine dihydrochloride

Conditions

Conditions	Yield
palladium In methanol; ethanol; water	97.5%
With hydrogenchloride; triethylamine In acetone - water; ethanol

: 108-20-3
di-isopropyl ether

: 125118-27-6
N-hydroxysuccinimide (11β,17α-dihydroxy-4-pregnene-3,20-dion-21-ylthio)acetate

: 125118-28-7
11β,17α-dihydroxy-21-(isopropyloxycarbonylmethylthio)-4-pregnen-3,20-dione

Conditions

Conditions	Yield
With diisopropylamine In 1,4-dioxane for 48h;	97.3%

: 2637-34-5
2-Mercaptopyridine

: 172732-37-5
1-(t-butoxycarbonyl)-4-(3-bromo-4-chloro-5-carboxy)phenylpiperazine

: 108-20-3
di-isopropyl ether

: 2524-64-3
chlorophosphoric acid diphenyl ester

: 172732-38-6
1-(t-butoxycarbonyl)-4-[3-bromo-4-chloro-5-(2-pyridylthio)carbonyl]phenylpiperazine

Conditions

Conditions	Yield
With sodium hydroxide; triethylamine In tetrahydrofuran	97%

...Expand

: 108-20-3
di-isopropyl ether

: 118721-49-6
1-(methylthio)-1-[(4-methylphenyl)sulfonyl]ethene

: 1-(3-Isopropoxy-3-methyl-1-methylsulfanyl-butane-1-sulfonyl)-4-methyl-benzene

Conditions

Conditions	Yield
With benzophenone for 0.5h; Irradiation;	96%

: 108-20-3
di-isopropyl ether

: 96042-30-7
4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

: 1251166-56-9
6-(4,5-dimethylthiazol-2-yl)-2-(4-trifluoromethylthiazol-2-yl)pyrimidin-4-ol

Conditions

Conditions	Yield
In trifluoroacetic acid	96%

: 108-20-3
di-isopropyl ether

: 74295-57-1
2,3-diisopropoxy-2,3-dimethylbutane

Conditions

Conditions	Yield
for 24h; Irradiation; with Hg photosensitization;	95%
With mercury for 16h; Irradiation; Yield given;

: 108-20-3
di-isopropyl ether

: 98-88-4
benzoyl chloride

: 117348-34-2
1-(pyridin-2-yl)-2-(2-aminobenzylthio)imidazole

: 1-(pyridin-2-yl)-2-(2-benzoylaminobenzylthio)imidazole

Conditions

Conditions	Yield
With potassium carbonate In dichloromethane; water	95%

...Expand

: 1-[1-(N-methyl-N-phenylcarbamoylmethyl)-2-oxo-5-cyclohexyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-3-yl]-3-(3-ethoxycarbonylphenyl)urea

aqueous lithiumhydroxide monohydrate: aqueous lithiumhydroxide monohydrate

: 108-20-3
di-isopropyl ether

: 209219-27-2
3-[3-[1-(N-methyl-N-phenylcarbamoylmethyl)-2-oxo-5-cyclohexyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-3-yl]ureido]benzoic acid

Conditions

Conditions	Yield
In tetrahydrofuran; methanol	95%

...Expand

: 108-20-3
di-isopropyl ether

: 75-29-6
isopropyl chloride

Conditions

Conditions	Yield
With tin(IV) chloride In dichloromethane at 110℃; for 60h; sealed tube; Inert atmosphere;	95%
With titanium tetrachloride In dichloromethane at 150℃; for 60h;

: 220821-38-5
4-hydroxy-5-isobutyryl-3-methyl-2-phenylthieno[ 2,3-b]pyridine

: 108-20-3
di-isopropyl ether

: 85118-00-9
2,6-Difluorobenzyl bromide

: 220820-76-8
7-(2,6-difluorobenzyl)-4,7-dihydro-5-isobutyryl-3-methyl-4-oxo-2-phenyl-thieno[2,3-b]pyridine

Conditions

Conditions	Yield
With potassium carbonate In water; ethyl acetate; N,N-dimethyl-formamide	94.6%

...Expand

: 108-20-3
di-isopropyl ether

: 98-88-4
benzoyl chloride

: 939-48-0
isopropyl benzoate

Conditions

Conditions	Yield
With iron In 1,2-dichloro-ethane at 70℃; for 7h; Schlenk technique; Inert atmosphere; regioselective reaction;	94%
With rhenium(I) pentacarbonyl bromide In 1,2-dichloro-ethane at 80℃; for 2h; Inert atmosphere;	76%
With aluminium trichloride; 1-ethyl-3-methylimidazolium iodide at 20℃; for 24h; Acylation;	58%
With rhenium(I) pentacarbonyl bromide In 1,2-dichloro-ethane at 80℃; for 2h; Inert atmosphere;	90 %Chromat.

: 7719-09-7
thionyl chloride

: 108-20-3
di-isopropyl ether

: 7036-56-8
(±)-1-(1-phenethyl)-1H-imidazole-5-carboxylic acid

: 7127-04-0
(+)-1-(1-phenylethyl)-1H-imidazole-5-carbonyl chloride hydrochloride

Conditions

Conditions	Yield
	94%

...Expand

: 429666-66-0
1-(4-carbamoyl-1,3-thiazol-2-yl)-3-hydroxyazetidine

: 108-20-3
di-isopropyl ether

: 124-63-0
methanesulfonyl chloride

: 1-(4-carbamoyl-1,3-thiazol-2-yl)-3-methanesulfonyloxyazetidine

Conditions

Conditions	Yield
With pyridine; triethylamine In methanol; dichloromethane	94%

...Expand

: 429668-53-1
1-(4-azetidinocarbonyl-1,3-thiazol-2-yl)-3-hydroxyazetidine

: 108-20-3
di-isopropyl ether

: 124-63-0
methanesulfonyl chloride

: 429668-55-3
1-(4-azetidinocarbonyl-1,3-thiazol-2-yl)-3-methanesulfonyloxyazetidine

Conditions

Conditions	Yield
With triethylamine In dichloromethane	94%

...Expand

: 108-20-3
di-isopropyl ether

: 1378801-67-2
3-Hydroxyethylindoline

Conditions

Conditions	Yield
With sodium hydroxide In ethanol	94%

: N-[2,3-dihydro-2-(iodomethyl)-2,4,6-trimethylbenzofuran-5-yl]formamide

: 108-20-3
di-isopropyl ether

: 67-63-0
isopropyl alcohol

: N-[2,3-dihydro-2-(iodomethyl)-7-isopropyl-2,4,6-trimethylbenzofuran-5-yl]formamide

Conditions

Conditions	Yield
With sulfuric acid In tetrahydrofuran	94%

...Expand

: 209219-89-6
1-(2-toluoylmethyl)-2-oxo-3-amino-5-(adamantan-1-yl)carbonyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepine

: 108-20-3
di-isopropyl ether

: 621-29-4
3-tolyl isocyanate

: 209217-97-0
1-[1-(2-toluoylmethyl)-2-oxo-5-(adamantan-1-yl)carbonyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepine-3-yl]-3-(3-methylphenyl)urea

Conditions

Conditions	Yield
In tetrahydrofuran; ethanol	93.1%

...Expand

: 108-20-3
di-isopropyl ether

: 106-94-5
propyl bromide

: 108-46-3
recorcinol

: 16533-50-9
m-propoxyphenol

Conditions

Conditions	Yield
With hydrogenchloride; sodium ethanolate; sodium In ethanol; toluene	93%

...Expand

: 108-20-3
di-isopropyl ether

: 122-01-0
4-chloro-benzoyl chloride

: 22913-11-7
isopropyl 4-chlorobenzoate

Conditions

Conditions	Yield
With rhenium(I) pentacarbonyl bromide In 1,2-dichloro-ethane at 80℃; for 2h; Inert atmosphere;	93%
With zinc(II) chloride at 25℃; for 12h;	68%
With rhenium(I) pentacarbonyl bromide In 1,2-dichloro-ethane at 80℃; for 12h; Inert atmosphere;	94 %Chromat.

: 80-56-8, 177698-18-9
Pinene

: 108-20-3
di-isopropyl ether

: 3(2),3(2),7-trimethyl-2,5-dioxo-6-oxa-3(1,3)-cyclobutanaoctaphane

Conditions

Conditions	Yield
Stage #1: Pinene; di-isopropyl ether With oxygen; ozone at 0℃; Stage #2: With semicarbazide hydrochloride at 20℃; for 48h; Inert atmosphere;	93%

Isopropyl ether Chemical Properties

IUPAC Name: 2-Propan-2-yloxypropane
Molecular Structure:
Molecular Formula: C₆H₁₄O
Molecular Weight: 102.17
CAS NO: 108-20-3
EINECS: 203-560-6
H bond acceptors: 1
H bond donors: 0
Freely Rotating Bonds: 2
Polar Surface Area: 9.23 Å²
Index of Refraction: 1.384
Molar Refractivity: 31.5 cm³
Molar Volume: 134.6 cm³
Surface Tension: 20.1 dyne/cm
Density: 0.758 g/cm³
Enthalpy of Vaporization: 29.1 kJ/mol
Flash Point: −29 °F
Boiling Point: 68.3 °C at 760 mmHg
Vapour Pressure: 152 mmHg at 25°C
Melting Point: -85.5 °C
Storage temp: Flammables area
Water Solubility: 9 g/L (20 °C)
Appearance: colourless liquid
Synonyms of Isopropyl ether (CAS NO.108-20-3): 2-Isopropoxypropane ; Diisopropylether ; DIPE
Stability: Stability Extremely flammable. This material is a serious fire and explosion risk. Vapour may travel considerable distances to an ignition source, which need not be an open flame, but may be a hot plate, steam pipe, etc. Vapour may be ignited by the static electricty which can build up when isopropyl ether is being poured from one vessel
SMILES: O(C(C)C)C(C)C
InChI: InChI=1/C6H14O/c1-5(2)7-6(3)4/h5-6H,1-4H3
InChIKey: ZAFNJMIOTHYJRJ-UHFFFAOYAC
Std. InChI: InChI=1S/C6H14O/c1-5(2)7-6(3)4/h5-6H,1-4H3
Std. InChIKey: ZAFNJMIOTHYJRJ-UHFFFAOYSA-N

Isopropyl ether Uses

Isopropyl ether (CAS NO.108-20-3) is used as standard materials for chromatographic analysis, solvent and extraction agent, and it is also used in organic synthesis.

Isopropyl ether Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mammal (species unspecified)	LC50	inhalation	130gm/m³ (130000mg/m³)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988.
mammal (species unspecified)	LD50	oral	6gm/kg (6000mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(10), Pg. 25, 1988.
mouse	LC50	inhalation	131gm/m³(131000mg/m³)	BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 19(10), Pg. 55, 1975.
mouse	LD50	intraperitoneal	812mg/kg (812mg/kg)		Shell Chemical Company. Unpublished Report. Vol. -, Pg. 5, 1961.
mouse	LD50	unreported	3600mg/kg (3600mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 19(10), Pg. 55, 1975.
rabbit	LC50	inhalation	121gm/m³ (121000mg/m³)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 19(10), Pg. 55, 1975.
rabbit	LD50	skin	20mL/kg (20mL/kg)		Union Carbide Data Sheet. Vol. 4/10/1968,
rabbit	LDLo	oral	6gm/kg (6000mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)	Journal of Industrial Hygiene and Toxicology. Vol. 21(3), Pg. 72, 1939.
rat	LC50	inhalation	162gm/m³ (162000mg/m³)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 19(10), Pg. 55, 1975.
rat	LD50	oral	8470mg/kg (8470mg/kg)		Union Carbide Data Sheet. Vol. 4/10/1968,
rat	LD50	unreported	5880mg/kg (5880mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 19(10), Pg. 55, 1975.

Isopropyl ether Safety Profile

Safety Information about Isopropyl ether (CAS NO.108-20-3):
Hazard Codes: F
Risk Statements: 11-19-66-67
R11: Highly flammable.
R19: May form explosive peroxides.
R66: Repeated exposure may cause skin dryness or cracking.
R67: Vapours may cause drowsiness and dizziness.
Safety Statements: 9-16-29-33
S9: Keep container in a well-ventilated place.
S16: Keep away from sources of ignition.
S29: Do not empty into drains.
S33: Take precautionary measures against static discharges.
RIDADR: UN 1159 3/PG 2
WGK Germany: 1
RTECS: TZ5425000
F: 10
HazardClass: 3
PackingGroup: II
Moderately toxic by intraperitoneal route. Mildly toxic by ingestion, inhalation, and skin contact. A skin irritant. A very dangerous fire hazard and severe explosion hazard when exposed to heat, flame, sparks, or oxidizers. Under some conditions shock will explode it. Dangerous; on exposure to air it rapidly forms very sensitive, explosive peroxides that precipitate as crystals. Violent reaction with chlorosulfonic acid, HNO₃. Potentially dangerous reaction with propionyl chloride can burst a sealed container. Reacts vigorously with oxidizing materials. To fight fire, use alcohol foam, CO₂, foam, dry chemical. When heated to decomposition it emits acrid smoke and fumes. See also ETHERS.

Isopropyl ether Standards and Recommendations

OSHA PEL: TWA 500 ppm
ACGIH TLV: TWA 250 ppm; STEL 310 ppm
DFG MAK: 500 ppm (2100 mg/m³)
DOT Classification: 3; Label: Flammable Liquid

Isopropyl ether Analytical Methods

For occupational chemical analysis use NIOSH: Isopropyl Ether S368.

Isopropyl ether Specification

Chemical Stability: Stable under normal temperatures and pressures. Light sensitive. May form explosive peroxides on prolonged storage.
Conditions to Avoid: High temperatures, incompatible materials, light, ignition sources, exposure to air.
Incompatibilities with Other Materials: Strong oxidizing agents, amines, mineral acids, aldehydes.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, peroxides.
Hazardous Polymerization: Will not occur.

Product Name

2-Isopropoxypropane

Synthetic route

Isopropyl ether Chemical Properties

Isopropyl ether Uses

Isopropyl ether Toxicity Data With Reference

Isopropyl ether Safety Profile

Isopropyl ether Standards and Recommendations

Isopropyl ether Analytical Methods

Isopropyl ether Specification

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