L-Glutamine supplier | CasNO.56-85-9

Name
L-Glutamine
EINECS 200-292-1
CAS No. 56-85-9
Article Data87
CAS DataBase
Density 1.321 g/cm³
Solubility water: 25 mg/mL
Melting Point 185 °C (dec.)(lit.)
Formula C₅H₁₀N₂O₃
Boiling Point 445.6 °C at 760 mmHg
Molecular Weight 146.146
Flash Point 223.3 °C
Transport Information
Appearance White crystalline powder
Safety 26-24/25-36/37/39-27
Risk Codes 36-36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms (S)-2,5-Diamino-5-oxopentanoic acid;Glutamine (VAN);L-Glutamid;Glutamine (USP);(2S)-2-amino-4-carbamoylbutanoic acid;(2S)-2-amino-4-carbamoyl-butanoic acid;L-2-Aminoglutaramic acid;Pentanoic acid, 2,5-diamino-5-oxo-, (S)-;Glutamine [USAN];(2S)-2-azaniumyl-4-carbamoyl-butanoate;Levoglutamina;Cebrogen;Levoglutamidum [INN-Latin];L-(+)-Glutamine;Glumin (amino acid);Levoglutamid;Miglu-P;Levoglutamide [DCF:INN];L-Glutamic acid .gamma.-amide;2-Aminoglutaramic acid;Levoglutamida [INN-Spanish];L-Glutamic acid gamma-amide;Levoglutamide;Glavamin;Glutamic acid 5-amide;(2S)-2,5-diamino-5-oxopentanoic acid;Glutamic acid amide;2,5-Diamino-5-oxopentanoic acid, (S)-;L(+)-Glutamine;L(+)-Glutamic acid-5-amide;H-Gln-OH;Glutamine (P347);Glutamine;L-Glutamine FCC5;L-Gln-OH;L-Glutamine;L-Glutamine FCC4;L-2-Aminoglutaramidic acid;2-Aminoglutaramic acid, L-;L-Glutamic acid 5-amide;2-amino-4-carbamoyl-butanoic acid;
PSA 106.41000
LogP 0.06440

Synthetic route

: 71989-20-3
N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-glutamine

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With sodium azide In N,N-dimethyl-formamide at 50℃; for 24h;	97%

: C42H33ClN4NiO4

A: 56-85-9
L-glutamine

: (R)-N-(2-benzoyl-4-chlorophenyl)-2-[3,5-dihydro-4H-dinaphtho[2,1-c:1',2'-e]azepine-4-yl]acetamide

Conditions

Conditions	Yield
With hydrogenchloride; water In methanol at 30℃; for 2h;	A n/a B 95%
With hydrogenchloride In methanol; water at 30℃; for 2h;	A 0.05 g B 95%

: 4-carbamoyl-2-[(E,Z)-4,4,4-trifluoro-3-oxo-1-butenylamino]butanoic acid

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With hydrogenchloride In methanol at 70℃; for 20h;	92%

: 4-carbamoyl-2-[(E,Z)-4,4,4-trichloro-3-oxo-1-butenylamino]butanoic acid

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With hydrogenchloride In methanol at 70℃; for 20h;	85%

: 56-86-0
L-glutamic acid

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With phosphoenolpyruvic acid; Imidazole-HCl buffer; ammonium chloride; adenosine 5'-diphosphate; magnesium chloride at 37℃; for 6h; pyruvate kinase, glutamine synthetase;	79%
With ammonia unter der Einwirkung von Enzym-Praeparaten aus verschiedenen tierischen Geweben;
With ammonia unter der Einwirkung von Streptococcus-Arten in Gegenwart von d-Glucose;

: (S)-3-(5'-oxo-9λ4-boraspiro[bicyclo[3.3.1]nonane-9,2'-[1,3,2]oxazaborolidin]-4'-yl)propanamide

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With tetrabutyl ammonium fluoride In tetrahydrofuran; water at 20℃; for 5h;	79%

: C5H10N2O3*H3N*ClH

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With ruthenium nanoparticles dispersed in a polyvinylpyrrolidone matrix; amberlyst A-21 In methanol; dichloromethane	59%

: 1820-73-1
glutamic acid γ-hydrazide

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With ethanol; nickel

: 55878-80-3
N-trityl-L-glutamic acid 5-methyl ester

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With ammonia Erwaermen des Reaktionsprodukts mit wss.Essigsaeure;

: 42749-49-5
5-amino-2(S)-{[(4-methylphenyl)sulfonyl]amino}-5-oxopentanoic acid

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With hydrogen bromide; acetic acid; phenol

: 125219-08-1
(S)-4-Carbamoyl-2-[2-(4-methoxy-phenyl)-2-oxo-ethoxycarbonylamino]-butyric acid

A: 56-85-9
L-glutamine

B: 100-06-1
1-(4-methoxyphenyl)ethanone

Conditions

Conditions	Yield
Irradiation; mild conditions;

: 142-47-2
monosodium glutamate

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With ammonium chloride In water at 30℃; for 0.166667h; γ-glutamylmethylamide synthetase from Methylophaga sp. AA-30, 0.5 M Tris HCl buffer pH 7.5, 2.5 M 2-mercaptoethanol, 0.1 M MnCl2, 0.1 M ATP; relative enzyme activity compared to methylamine, Km;

: 142998-32-1
Puwainaphycin E

A: 72-18-4
L-valine

B: 56-85-9
L-glutamine

C: 138754-66-2
(2R,3R,4S)-3-Amino-2-hydroxy-4-methyl-hexadecanoic acid

D: 147-85-3
L-proline

Conditions

Conditions	Yield
With hydrogenchloride at 100℃; for 24h; Further byproducts given;

...Expand

: 142998-31-0
Puwainaphycin B

A: 72-18-4
L-valine

B: 56-85-9
L-glutamine

C: (2R,3R,4S)-3-Amino-2-hydroxy-4-methyl-14-oxo-octadecanoic acid

D: 147-85-3
L-proline

Conditions

Conditions	Yield
With hydrogenchloride at 100℃; for 24h; Further byproducts given;

...Expand

: 98115-14-1
Nα,Nca-di-tert-butyloxycarbonylglutamine

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With hydrogen bromide In acetic acid

: Boc-L-Glu-γ-DHA-CONHCH3

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With hydrogenchloride; water In acetic acid at 55℃; for 0.833333h;

: 6232-22-0
(S)-2-amino-4-cyano-butyric acid

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With Tris-HCl buffer; N74D Escherichia coli asparagine synthetase B mutant; BIS-TRIS; magnesium chloride at 37℃; for 0.333333h; pH=6.5; Enzyme kinetics; Further Variations:; Reagents; pH-values; Hydrolysis;

-5-amide: -5-amide

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With sodium carbonate; hydrazine

-1-benzyl ester-5-amide: -1-benzyl ester-5-amide

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With methanol; palladium; acetic acid Hydrogenolyse;

-5-amide: -5-amide

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With palladium; acetic acid Hydrogenolyse;
With palladium; acetic acid Hydrogenolyse;
With phosphonium iodide; acetic acid at 40 - 50℃;
With palladium; acetic acid Hydrogenolyse;
With palladium; acetic acid Hydrogenolyse;

: 13907-82-9, 2650-67-1
N2-benzyloxycarbonyl-L-glutamine methyl ester

aqueous NaOH: aqueous NaOH

A: 636-65-7
glutamine

B: 56-85-9
L-glutamine

Conditions

Conditions	Yield
Ansaeuern mit wss. HCl und Hydrieren des Reaktionsgemisches an Palladium;

...Expand

: 51163-40-7
(S)-methyl 5-amino-4-{[(benzyloxy)carbonyl]amino}-5-oxopentanoate

aqueous NaOH: aqueous NaOH

A: 636-65-7
glutamine

B: 56-85-9
L-glutamine

Conditions

Conditions	Yield
Ansaeuern mit wss. HCl und Hydrieren des Reaktionsgemisches an Palladium;

...Expand

: N-lauroyl-L-glutamine

A: 143-07-7
lauric acid

B: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With acylase I from pig kidney; water In glycerol at 37℃; for 3h; pH=7.5; Equilibrium constant;

: 56-85-9, 585-21-7, 5959-95-5, 6899-04-3
GLUTAMINE

A: 5959-95-5
D-Glutamin

B: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With (2R,3R,11R,12R)-(+)-18-crown-6-2,3,11,12-tetracarbonic acid
With R-(3,3'-dibromo-1,1'-binaphthyl)-20-crown-6 coated C18 silica gel column at 25℃; pH=2; Resolution of racemate;

: (R)-2-((E)-(R)-4-{(2S,3S)-2-[(S)-2-({(S)-1-[(S)-1-(2-Amino-acetyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonyl}-amino)-4-carbamoyl-butyrylamino]-3-methyl-pentanoylamino}-6-methyl-hept-2-enoylamino)-3-(1H-indol-3-yl)-propionic acid

A: 2-[(2E,4R)-4-amino-6-methylhept-2-enoylamino]-(2R)-3-(indol-3-yl)propanoic acid

B: 73-32-5
L-isoleucine

C: 56-85-9
L-glutamine

D: 56-40-6
glycine

E Pro: Pro

Conditions

Conditions	Yield
With sodium phosphate buffer; leucine amino peptidase at 37℃; pH=7.2; Title compound not separated from byproducts;

...Expand

: (R)-2-((E)-(S)-4-{(2S,3S)-2-[(S)-2-({(S)-1-[(S)-1-(2-Amino-acetyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carbonyl}-amino)-4-carbamoyl-butyrylamino]-3-methyl-pentanoylamino}-6-methyl-hept-2-enoylamino)-3-(1H-indol-3-yl)-propionic acid

A: 2-[(2E,4S)-4-amino-6-methylhept-2-enoylamino]-(2R)-3-(indol-3-yl)propanoic acid

B: 73-32-5
L-isoleucine

C: 56-85-9
L-glutamine

D: 56-40-6
glycine

E Pro: Pro

Conditions

Conditions	Yield
With sodium phosphate buffer; leucine amino peptidase at 37℃; pH=7.2; Title compound not separated from byproducts;

...Expand

: 142-47-2
monosodium L-glutamate

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
With Pseudomonas taetrolens Y-30 glutamine synthetase EC 6.3.1.2; ammonium chloride; magnesium chloride; imidazole buffer at 30℃; pH=8.0; Enzyme kinetics; Further Variations:; pH-values; Reagents;

: 30924-93-7
Boc-Glu-OBn

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 2: 1 N HCl, H2O / acetic acid / 0.83 h / 55 °C View Scheme

: 4561-10-8
L-glutamic acid dibenzyl ester hydrochloride

: 56-85-9
L-glutamine

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: triethylamine; CHCl3 2: methanol. sodium methylate 3: palladium; triethylamine; cyclohexane / Hydrogenation 4: methanol.NH3 / Erwaermen des Reaktionsprodukts mit wss.Essigsaeure View Scheme

: 56-85-9
L-glutamine

: 120362-25-6
methyl 1-β-D-ribofuranosyl-1,2,4-triazole-3-carboximidate

: 142633-85-0
1-β-D-ribofuranosyl-1,2,4-triazole-3-N-(α-carboxy-4'-butyramido)carboxamidine

Conditions

Conditions	Yield
In methanol for 168h; Ambient temperature;	100%

: 56-85-9
L-glutamine

: 17720-18-2
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate

: 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate (S)-5-amino-2-ammonio-5-oxopentanoate

Conditions

Conditions	Yield
In water pH=4.95; Cooling with ice;	100%

: 56-85-9
L-glutamine

: nicotinic acid riboside 5'-monophosphate

: (S)-4-amino-1-carboxy-4-oxobutan-1-aminium 1-((2R,3R,4S,5R)-5-(((hydrogenphosphonato)oxy)methyl)-3,4-dihydrotetrahydrofuran-2-yl)pyridine-1-ium-3-carboxylate

Conditions

Conditions	Yield
In water at 10℃; pH=Ca. 2.3 - 2.5;	100%

: 56-85-9
L-glutamine

: nicotinic acid riboside 5'-monophosphate

: bis((S)-4-amino-1-carboxy-4-oxobutan-1-aminium)-1-((2R,3S,4R,5R)-3,4-dihydroxy-5-((phosphonatooxy)methyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate

Conditions

Conditions	Yield
In water at 10℃; pH=Ca. 2.8;	100%

: 56-85-9
L-glutamine

: 141-43-5
ethanolamine

: nicotinic acid riboside 5'-monophosphate

: 2-hydroxyethan-1-aminium (S)-4-amino-1-carboxy-4-oxobutan-1-aminium 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-((phosphonatooxy)methyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate

Conditions

Conditions	Yield
In water pH=2.1 - 5.06; Inert atmosphere; Cooling with ice;	100%

...Expand

: 56-85-9
L-glutamine

: 108-24-7
acetic anhydride

: 2490-97-3
N-acetyl-L-glutamine

Conditions

Conditions	Yield
In water for 0.0666667h; Irradiation;	99%
With sodium hydroxide

: 56-85-9
L-glutamine

: 10068-65-2
Z-Thr(But)-ONSu

: 138541-15-8
Z-L-Thr(tBu)-L-Gln-OH

Conditions

Conditions	Yield
With sodium hydrogencarbonate In 1,4-dioxane; water for 48h; Ambient temperature;	99%

: potassium hexachloropalladate

: 56-85-9
L-glutamine

: 119363-27-8
trans-Pd(L-Gln-O)2

Conditions

Conditions	Yield
With sodium hydroxide In water aq. soln. of K2PdCl6 and amino-acid was stirred and to the mixt. was dropped 1 N NaOH within 20 min, stirring was continued for 18 h; soln. was filtered, residue was washed with water, then ethanol and ether and dried in vac. over P2O5; elem. anal.;	99%

: 56-85-9
L-glutamine

: 16624-64-9
α-carbobenzoxy-L-tryptophan p-nitrophenyl ester

: 1105050-57-4
N-benzyloxycarbonyl-L-tryptophan-L-glutamine

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran; water at 20℃;	99%

: 56-85-9
L-glutamine

: 501-53-1
benzyl chloroformate

: 2650-64-8
Cbz-L-Gln

Conditions

Conditions	Yield
With sodium carbonate In 1,4-dioxane; water at 0 - 20℃; Inert atmosphere;	98%
With sodium hydroxide In water; toluene at 25 - 30℃; pH=11 - 12;	88.5%
Stage #1: L-glutamine; benzyl chloroformate With sodium hydrogencarbonate In water; toluene at 20℃; Inert atmosphere; Stage #2: With hydrogenchloride In water	86%

: 56-85-9
L-glutamine

: 250296-57-2
N-Benzyloxycarbonyl-N-trifluoromethylsulfonyl-4-trifluoromethylanilide

: 2650-64-8
Cbz-L-Gln

Conditions

Conditions	Yield
With water; triethylamine In 1,4-dioxane at 20℃; for 1h; Acylation;	98%

: 56-85-9
L-glutamine

: 1644308-43-9
(R)-N-(2-benzoyl-4-chlorophenyl)-1-[(3,4-dichlorophenyl)methyl]-2-pyrrolidinecarboxamide

: 6018-89-9
nickel(II) acetate tetrahydrate

: C30H27Cl3N4NiO4

Conditions

Conditions	Yield
With potassium carbonate In methanol at 60℃; for 3h; Temperature;	98%

...Expand

: 56-85-9
L-glutamine

: 38050-71-4
9-methoxy-9-BBN

: (S)-3-(5'-oxo-9λ4-boraspiro[bicyclo[3.3.1]nonane-9,2'-[1,3,2]oxazaborolidin]-4'-yl)propanamide

Conditions

Conditions	Yield
In methanol; hexane for 1h; Reflux;	98%

: manganese (II) nitrate tetrahydrate

: 56-85-9
L-glutamine

: Mn(OC(O)CH(NH2)CH2CH2C(O)NH2)2

Conditions

Conditions	Yield
With lithium hydroxide In ethanol refluxing (1.5 h), Mn-salt addn., refluxing (1.5 h); filtering (room temp.), drying (25°C); elem. anal.;	95.3%

: 56-85-9
L-glutamine

: 24424-99-5
di-tert-butyl dicarbonate

: 13726-85-7
Boc-Gln-OH

Conditions

Conditions	Yield
	95%
Stage #1: L-glutamine With sodium hydroxide In 1,4-dioxane; water Large scale; Stage #2: di-tert-butyl dicarbonate In 1,4-dioxane at 0 - 20℃; for 4h; Reagent/catalyst; Solvent; Temperature; Large scale;	90.7%
With sodium hydroxide In 1,4-dioxane for 1h;	90%

: 56-85-9
L-glutamine

: 123-41-1
cholin hydroxide

: 1361335-92-3
2-hydroxyethyltrimethylammonium L-glutaminate

Conditions

Conditions	Yield
In water at 3℃; for 48h; Darkness;	95%

: 56-85-9
L-glutamine

: 103-72-0
phenyl isothiocyanate

: 29588-05-4
3-(5-oxo-1-phenyl-2-thioxoimidazolidin-4-yl)propanamide

Conditions

Conditions	Yield
With triethylamine In water; N,N-dimethyl-formamide at 20℃; for 3h;	95%

: 56-85-9
L-glutamine

: 116869-01-3
2,2-bis(4'-nitrophenyl)ethyl-N-succinimidyl carbonate

: 138296-31-8
Nα-<2,2-bis(4'-nitrophenyl)ethoxycarbonyl>-glutamine

Conditions

Conditions	Yield
With triethylamine In 1,4-dioxane; water Ambient temperature;	94%

: 3338-34-9
Z-Lys(-Boc)-Osu

: 56-85-9
L-glutamine

: 68171-87-9
Z-Lys(Boc)-Gln-OH

Conditions

Conditions	Yield
With sodium hydroxide In 1,4-dioxane at 0 - 20℃; for 123h;	93%

: 56-85-9
L-glutamine

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 71989-20-3
N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-glutamine

Conditions

Conditions	Yield
With sodium carbonate In 1,4-dioxane; water at 0 - 20℃;	93%
With sodium carbonate In tetrahydrofuran; water	84%
Stage #1: L-glutamine With N-cyclohexyl-cyclohexanamine In acetone at 20℃; Stage #2: N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide With sodium carbonate In water; acetonitrile at 0 - 20℃; pH=8; Stage #3: With potassium hydrogensulfate In water; acetonitrile pH=2 - 3;	54%

: 56-85-9
L-glutamine

: 98-59-9
p-toluenesulfonyl chloride

: 42749-49-5
5-amino-2(S)-{[(4-methylphenyl)sulfonyl]amino}-5-oxopentanoic acid

Conditions

Conditions	Yield
With magnesium oxide In water at 5℃;	92%
With sodium hydroxide In 1,4-dioxane for 2.5h;	73%
With sodium hydroxide In water at 80 - 90℃;	58%

: 56-85-9
L-glutamine

: 77-98-5
tetraethylammonium hydroxide

: 1248586-10-8
tetraethylammonium L-glutaminate

Conditions

Conditions	Yield
In water at 20℃; for 2h;	91%

: 56-85-9
L-glutamine

: 2,7-disulfo-9-fluorenylmethoxycarbonyl chloride

: C20H18N2O11S2(2-)*2Na(1+)

Conditions

Conditions	Yield
With sodium hydrogencarbonate In water at 20℃; for 0.5h; pH=8.5;	90.8%

: 1076-38-6
4-hydroxy[1]benzopyran-2-one

: 56-85-9
L-glutamine

: 122-51-0
orthoformic acid triethyl ester

: N-(methylene-4-oxocoumarinyl)-L-glutamine

Conditions

Conditions	Yield
In isopropyl alcohol for 2h; Heating;	90%

...Expand

: 56-85-9
L-glutamine

: 74197-40-3
3,5-dinitro-1-(4-nitrophenyl)-4-pyridone

A: 100-01-6
4-nitro-aniline

B: (S)-4-Carbamoyl-2-(3,5-dinitro-4-oxo-4H-pyridin-1-yl)-butyric acid

Conditions

Conditions	Yield
In pyridine; water for 2h; Ambient temperature;	A n/a B 90%

...Expand

: 56-85-9
L-glutamine

: 66891-86-9
benzyl (4-(chlorocarbonyl)phenyl)(methyl)carbamate

: 96845-85-1
N2-<4-<<(benzyloxy)carbonyl>methylamino>benzoyl>-L-glutamine

Conditions

Conditions	Yield
With sodium hydroxide In 1,4-dioxane at 0 - 5℃;	90%

: 56-85-9
L-glutamine

: 75-04-7
ethylamine

: 3081-61-6, 5822-62-8, 17010-37-6, 34271-54-0
N-ethyl-L-glutamine

Conditions

Conditions	Yield
With recombinant Bacillus subtilis γ-glutamyltranspeptidase In water at 37℃; for 5h; pH=10; Concentration; pH-value; Temperature; Enzymatic reaction;	90%
With glutaminase from Pseudomonas nitroreducens IFO 12694; imidazole buffer In water at 30℃; relative rate of glutamyl transfer;
biosynthesis by immobilized cells of Pseudomonas nitroreducens;
With recombinant Pseudomonas nitroreducens IFO12694 γ-glutamyltranspeptidase at 30℃; for 0.333333h; pH=10.5; aq. buffer; Enzymatic reaction;
With glutaminase immobilised on SBA-15 type mesoporous silica at 20℃; for 1h; Reagent/catalyst; pH-value; Temperature; Flow reactor; Enzymatic reaction;

L-Glutamine Consensus Reports

L-Glutamine (CAS NO.77668-42-9) is reported in EPA TSCA Inventory.

L-Glutamine Specification

L-Glutamine, with the IUPAC Name of (2S)-2,5-Diamino-5-oxopentanoic acid, is one kind of white crystalline powder. And its Classification Code are including Dietary supplement; Drug / Therapeutic Agent; Human Data; Mutation data. L-Glutamine(CAS NO.56-85-9) is the most abundant amino acid (building block of protein) in the body. The popular amino acid L-Glutamine is found in protein powders, beans, meats, fish, poultry, dairy products, and of course. It is used in the gut and immune system to maintain optimal performance. 60% of free-form amino acids floating in skeletal muscles is L-Glutamine.

Physical properties about L-Glutamine are: (1)ACD/LogP: -1.576; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): -4.08; (4)ACD/LogD (pH 7.4): -4.08; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 1.00; (8)ACD/KOC (pH 7.4): 1.00; (9)#H bond acceptors: 5; (10)#H bond donors: 5; (11)#Freely Rotating Bonds: 5; (12)Index of Refraction: 1.524; (13)Molar Refractivity: 33.837 cm³; (14)Molar Volume: 110.546 cm³; (15)Polarizability: 13.414 10-24cm³; (16)Surface Tension: 64.588996887207 dyne/cm; (17)Density: 1.322 g/cm³; (18)Flash Point: 223.272 °C; (19)Enthalpy of Vaporization: 77.128 kJ/mol; (20)Boiling Point: 445.568 °C at 760 mmHg

Uses of L-Glutamine:
1). L-Glutamine (CAS NO.77668-42-9) has been studied extensively over the past 10–15 years and has been shown to be useful in treatment of serious illnesses, injury, trauma, burns, cancer and its treatment related side-effects as well as in wound healing for postoperative patients.
2). Glutamine is also marketed as a supplement used for muscle growth in weightlifting, bodybuilding, endurance, and other sports.
3). Glutamine has also been taken to enhance brain function as it fuels two of the brain's most important neurotransmitters.
4). It has also been used in the treatment of ADHD, anxiety，and depression.
5). It has also been used in recovery programs to break sugar craving cycles in alcoholics and assist diabetics in the management of sugar cravings.
6). It is also used as an anti-inflammatory in the treatment of autoimmune diseases and preserves Glutathione levels in the liver.

You can still convert the following datas into molecular structure:
(1)InChI=1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1;
(2)InChIKey=ZDXPYRJPNDTMRX-VKHMYHEASA-N;
(3)SmilesC([C@@H](C(=O)O)N)CC(N)=O

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	oral	27mg/kg/1W-I (27mg/kg)	BEHAVIORAL: EUPHORIA	American Journal of Psychiatry. Vol. 141, Pg. 1302, 1984.
mouse	LD50	oral	21700mg/kg (21700mg/kg)		Drugs in Japan Vol. 6, Pg. 228, 1982.
rat	LD50	oral	7500mg/kg (7500mg/kg)		Drugs in Japan Vol. 6, Pg. 228, 1982.

Product Name

L-Glutamine

Synthetic route

L-Glutamine Consensus Reports

L-Glutamine Specification

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