Luteolin supplier | CasNO.491-70-3

Name
Luteolin
EINECS 207-741-0
CAS No. 491-70-3
Article Data100
CAS DataBase
Density 1.654 g/cm³
Solubility Soluble in aqueous alkaline solutions (1.4 mg/ml), ethanol (~5 mg/ml), dimethyl sulfoxide (7 mg/ml), 1eq. Sodium hydroxide (5 mM), dimethylformamide (~20 mg/ml), water (1 mg/ml) at 25°C and methanol.
Melting Point ~330 °C(lit.)
Formula C₁₅H₁₀O₆
Boiling Point 616.1 °C at 760 mmHg
Molecular Weight 286.241
Flash Point 239.5 °C
Transport Information
Appearance yellow crystalline powder
Safety 26-36-36/37/39
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms 4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-;Cyanidenon 1470;Prestwick_122;Flacitran;4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy- (9CI);2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-benzopyrone;2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one;4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-;3,4,5,7-Tetrahydroxyflavone;5,7,3,4-Tetrahydroxyflavone;C.I. Natural Yellow 2;2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-chromen-4-one;C.I. 75590;Luteolol;Digitoflavone;3',4',5,7-Tetrahydroxyflavone;
PSA 111.13000
LogP 2.28240

Synthetic route

: 520-36-5
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
With C9H8IO4Pol In dimethyl sulfoxide at 25℃; for 2h;	95%
With cytochromes P450 in human liver microsomes Kinetics; Enzymatic reaction;

: 855-97-0
2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-4H-chromen-4-one

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
With pyridine hydrochloride at 190℃; for 6h; Inert atmosphere;	89%
With pyridine hydrochloride at 180℃; for 6.5h; Inert atmosphere;	88%
Stage #1: 2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-4H-chromen-4-one With aluminum (III) chloride In toluene at 80 - 140℃; Stage #2: With hydrogenchloride In water; toluene at 0℃; Reagent/catalyst; Solvent; Temperature; Time;	70.2%

: 58124-13-3
2-(3,4-bis(benzyloxy)phenyl)-5,7-dihydroxy-4H-chromen-4-one

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal In N,N-dimethyl-formamide Ambient temperature;	80%

: 1-[3,4-Bis-(tert-butyl-dimethyl-silanyloxy)-phenyl]-3-(2,4,6-trihydroxy-phenyl)-propane-1,3-dione

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
With sulfuric acid In acetic acid at 95 - 100℃; for 1h;	78%

: 14917-41-0
2',3,4,4',6'-pentahydroxychalcone

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
With oxygen at 20℃; under 760.051 Torr; for 1h; Reagent/catalyst;	72%

: 5373-11-5, 68321-11-9
luteolin 7-O-glucoside

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
With sulfuric acid for 4h;	68.2%
With acid
With sulfuric acid; water for 2h; Heating;	70 mg

: 5373-11-5, 68321-11-9
luteolin 7-O-glucoside

A: 50-99-7
D-glucose

B: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
With water Acidic conditions;	A n/a B 66%
Acid hydrolysis;
Acidic aq. solution;
Acidic conditions;

: 4,6-bis(methoxymethyl)-2-(3,4-diacetoxybenzoyloxy)acetophenone

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
Stage #1: 4,6-bis(methoxymethyl)-2-(3,4-diacetoxybenzoyloxy)acetophenone With potassium hydroxide In pyridine at 50℃; for 0.333333h; Stage #2: With acetic acid In pyridine; water for 0.5h; Stage #3: With hydrogenchloride In methanol Reflux;	55%

: 3563-98-2, 20633-84-5
scolymoside

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
With sulfuric acid; water for 2h; Heating;	50%

: 480-40-0
5,7-dihydroxy-2-phenyl-chromen-4-one

A: 520-36-5
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

B: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

C: luteolin 3'-monosulphate

Conditions

Conditions	Yield
With Mucore ramannianus (ATCC 9628) In N,N-dimethyl-formamide for 336h; Microbiological reaction;	A 3% B 10.2% C 10.2%

...Expand

: 6-bromo-2-(3,4-dimethoxy-phenyl)-5,7-dimethoxy-chromen-4-one

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
With water; hydrogen iodide; acetic anhydride

: 520-34-3
diosmetin

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
With pyridine hydrochloride at 170℃; for 2h;

: luteolin 7-O-<β-D-glucuronosyl(1-2)β-D-glucuronide>-4'-O-β-D-glucuronide

A: 489-91-8, 528-16-5, 552-12-5, 577-46-8, 643-33-4, 2240-07-5, 6294-16-2, 10133-02-5, 18402-78-3, 18968-14-4, 21179-08-8, 23018-83-9, 33599-45-0, 33599-46-1, 46171-67-9, 46171-69-1, 46172-26-3, 70021-34-0, 71031-08-8, 104195-06-4, 106499-29-0, 124817-72-7
D-glucuronic acid

B: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

C: luteolin 7-O-<β-D-glucuronosyl(1<*>2)β-D-glucuronide>

Conditions

Conditions	Yield
With formic acid In water at 100℃; for 3h; Product distribution; also enzymatic hydrolysis;

...Expand

: 5373-11-5, 68321-11-9
luteolin 7-O-glucoside

A: 2280-44-6
D-Glucose

B: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
With hydrogenchloride
With sulfuric acid for 6h;

: 5373-11-5, 68321-11-9
luteolin 7-O-glucoside

A: 492-61-5
β-D-glucose

B: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
Product distribution; Acid hydrolysis;

: 20344-46-1
luteolin-5-O-β-D-glucopyranoside

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
With malic acid at 60℃; other object of study: half-lives; other reagent : acetic acid, oxalic acid, HCl; other temperature;

: 126394-95-4
7-O-lactoyl-luteolin

A: 849585-22-4
LACTIC ACID

B: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
With hydrogenchloride In methanol at 100℃; for 7h; Product distribution;

: luteolin 7-O-<2-O-β-glucopyranosyl-lactate>

A: 849585-22-4
LACTIC ACID

B: 2280-44-6
D-Glucose

C: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
With hydrogenchloride at 100℃; for 7h; Product distribution; other time; reaction in the presence of catalyst;

...Expand

: luteolin 7-O-<2-O-β-glucopyranuronosoyl-lactate>

A: 849585-22-4
LACTIC ACID

B: 6556-12-3, 489-91-8, 528-16-5, 552-12-5, 577-46-8, 643-33-4, 2240-07-5, 6294-16-2, 10133-02-5, 18402-78-3, 18968-14-4, 21179-08-8, 23018-83-9, 33599-45-0, 33599-46-1, 46171-67-9, 46171-69-1, 46172-26-3, 70021-34-0, 71031-08-8, 104195-06-4, 106499-29-0, 124817-72-7
D-glucuronic acid

C: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
With hydrogenchloride at 100℃; for 7h; Product distribution; other time; reaction in the presence of catalyst;

...Expand

: 169132-97-2
(3',4'-dibenzyloxy-5,7-dimethoxymethyl)flavone

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
With hydrogenchloride In methanol
Multi-step reaction with 3 steps 1: 75 percent / HCl / ethanol; hexane / 1 h / Ambient temperature 2: 18percent HCl / ethanol / 0.5 h / Heating 3: 80 percent / H2 / Pd/C / dimethylformamide / Ambient temperature View Scheme

: 3-<3,4-di(tert-butyldimethylsilyloxy)phenyl>-5-(2,4,6-trihydroxyphenyl)isoxazole

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
With hydrogenchloride; hydrogen; boric acid; acetic acid; nickel 1.) dioxane-water, 2.) 2 h, reflux; Yield given. Multistep reaction;

2.4.6-trimethoxy-ω-<3.4-dimethoxy-benzoyl>-acetophenone: 2.4.6-trimethoxy-ω-<3.4-dimethoxy-benzoyl>-acetophenone

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
With hydrogen iodide

2.4.6-trimethoxy-ω-<3.4-methylenedioxy-benzoyl>-acetophenone: 2.4.6-trimethoxy-ω-<3.4-methylenedioxy-benzoyl>-acetophenone

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions

Conditions	Yield
With hydrogen iodide

: 520-34-3
diosmetin

: 10034-85-2
hydrogen iodide

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 10544-05-5
2-(3,4-dimethoxy-phenyl)-7-hydroxy-5-methoxy-chromen-4-one

: 10034-85-2
hydrogen iodide

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 89029-12-9
3',4'-methylenedioxy-5,7-dimethoxyflavone

: 10034-85-2
hydrogen iodide

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 6,8-dibromo-2-(3,4-dimethoxy-phenyl)-5,7-dimethoxy-chromen-4-one

: 10034-85-2
hydrogen iodide

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 6169-14-8
5,7-diethoxy-2-(3,4-diethoxy-phenyl)-chromen-4-one

: 10034-85-2
hydrogen iodide

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 10034-85-2
hydrogen iodide

: 3162-04-7
chrysoeriol tri-O-acetate

: 64-19-7
acetic acid

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

...Expand

: 764-09-0
chlorosulfuric acid 2,2,2-trichloroethyl ester

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: C23H14Cl12O18S4

Conditions

Conditions	Yield
With dmap; triethylamine In tetrahydrofuran at 20℃;	95%

: 617-89-0
furan-2-ylmethanamine

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: C20H13NO7

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; water pH=9.2; Reflux;	95%

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 108-24-7
acetic anhydride

: 1061-93-4
luteolin tetraacetate

Conditions

Conditions	Yield
With pyridine Reflux;	92%
With sodium acetate
In pyridine Ambient temperature;	49 mg

: 1269657-45-5
TFE*OTf

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 1313434-36-4
C23H18Cl12O18S4

Conditions

Conditions	Yield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 20℃; for 0.366667h;	92%

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 929-06-6
2-(2-Aminoethoxy)ethanol

: C19H17NO8

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; water at 65℃; pH=9.2;	92%

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 814-49-3
diethyl chlorophosphate

: 1266147-86-7
C31H46O18P4

Conditions

Conditions	Yield
With dmap; triethylamine In tetrahydrofuran at 20℃; for 24.5h; Inert atmosphere; Cooling with ice;	91%
With dmap; triethylamine In tetrahydrofuran at 70℃; for 3.5h; Cooling with ice; Inert atmosphere;

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 77-78-1
dimethyl sulfate

: 855-97-0
2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-4H-chromen-4-one

Conditions

Conditions	Yield
With potassium carbonate In acetone for 10h; Reflux;	90.7%
With potassium carbonate; acetone

: 1185733-70-3
2,2,2-trichloroethoxysulfuryl 2-methyl-3-methylimidazolium triflate

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 1313434-36-4
C23H18Cl12O18S4

Conditions

Conditions	Yield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 20℃; for 0.366667h;	90%

: 186581-53-3, 908094-01-9
diazomethane

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: (1S,2R,4aS,6aR,6bR,8aR,12aR,12bR,14bS)-6a-Hydroxymethyl-1,2,6b,9,9,12a-hexamethyl-10-oxo-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydro-2H-picene-4a-carboxylic acid methyl ester

Conditions

Conditions	Yield
In methanol for 0.5h; Ambient temperature;	88%

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 147-85-3
L-proline

: luteolin L-proline cocrystals (1:1)

Conditions

Conditions	Yield
In ethanol; acetonitrile at 50℃;	86.3%

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 142-61-0
Hexanoyl chloride

: 5,7,3',4'-tetra-O-hexanoyl-luteolin

Conditions

Conditions	Yield
With dmap; triethylamine In N,N-dimethyl-formamide at 20℃; for 4.5h; Cooling with ice;	85%
With dmap; triethylamine In N,N-dimethyl-formamide

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 74-88-4
methyl iodide

: 855-97-0
2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-4H-chromen-4-one

Conditions

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 12h;	84%

: 2051-90-3
Dichlorodiphenylmethane

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 1201808-21-0
2-(2,2-diphenyl-1,3-benzodioxol-5-yl)-5,7-dihydroxy-4H-1-benzopyran-4-one

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In 1,4-dioxane; 1-methyl-pyrrolidin-2-one at 180℃; for 1h; Inert atmosphere; Sealed tube; Microwave irradiation;	83%
In diphenylether at 165℃; for 2.5h;	70%
In diphenylether at 165℃; for 2.5h;	70%

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

A: 120537-30-6
C15H9O9S(1-)*K(1+)

B: 116097-10-0
C15H8O12S2(2-)*2K(1+)

Conditions

Conditions	Yield
With potassium acetate; tetra(n-butyl)ammonium hydrogensulfate; dicyclohexyl-carbodiimide In pyridine at 4℃; for 72h; Yields of byproduct given;	A n/a B 78%

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 5,7-dihydroxy-2-(3,4-dihydroxyphenyl-2,5,6-D3)-4H-1-benzopyran-4-one-3,6,8-D3

Conditions

Conditions	Yield
With boron trifluoride; [D3]phosphoric acid In water-d2 at 55℃; for 48h; deuteration;	78%

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 106-93-4
ethylene dibromide

: 445408-53-7
2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-5,7-dihydroxy-4H-chromen-4-one

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 70℃; for 0.5h;	78%
With potassium carbonate In dimethyl sulfoxide at 70℃; for 1h;	32.4%
With potassium carbonate In N,N-dimethyl-formamide at 70℃; for 0.5h;	28.1%

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 141-43-5
ethanolamine

: C17H13NO7

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; water at 65℃; pH=9.2;	78%

: 107-10-8
propylamine

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: C18H15NO6

Conditions

Conditions	Yield
With sodium hydroxide In ethanol at 50℃; pH=9.2;	76%

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 77-78-1
dimethyl sulfate

: 32174-62-2
pilloin

Conditions

Conditions	Yield
With potassium carbonate In acetone for 1h; Reflux;	73%
With potassium carbonate In N,N-dimethyl-formamide at 60 - 65℃; for 3h;	20.9%

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 75-04-7
ethylamine

: C17H13NO6

Conditions

Conditions	Yield
With sodium hydroxide In ethanol; water at 50℃; pH=9.2-9.3;	72%

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 100-39-0
benzyl bromide

: 1201807-92-2
7-(benzyloxy)-2-(3',4'-bis(benzyloxy)phenyl)-5-hydroxy-4H-chromen-4-one

Conditions

Conditions	Yield
Stage #1: 2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 20℃; for 1h; Inert atmosphere; Stage #2: benzyl bromide In N,N-dimethyl-formamide at 80℃; for 10h; Inert atmosphere;	71%
With potassium carbonate In N,N-dimethyl-formamide at 0 - 20℃;	56%

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 100-46-9
benzylamine

: C22H15NO6

Conditions

Conditions	Yield
With sodium hydroxide In ethanol at 50℃; pH=9.2; Sonication;	70.1%

: 33966-50-6
SEC-BUTYLAMINE

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: C19H17NO6

Conditions

Conditions	Yield
With sodium hydroxide In ethanol at 50℃; pH=9.2;	68%

: 491-70-3
2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

: 106-95-6
allyl bromide

: C27H26O6

Conditions

Conditions	Yield
With potassium carbonate In acetone for 10h; Reflux;	67.6%

Luteolin Chemical Properties

Molecular Structure of Luteolin (CAS NO.491-70-3):

IUPAC Name: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one
Empirical Formula: C₁₅H₁₀O₆
Molecular Weight: 286.2363
H bond acceptors: 6
H bond donors: 4
Freely Rotating Bonds: 5
Polar Surface Area: 63.22Å²
Index of Refraction: 1.767
Molar Refractivity: 71.73 cm³
Molar Volume: 172.9 cm³
Surface Tension: 92.5 dyne/cm
Density: 1.654 g/cm³
Flash Point: 239.5 °C
Enthalpy of Vaporization: 94.73 kJ/mol
Boiling Point: 616.1 °C at 760 mmHg
Vapour Pressure: 9.03E-16 mmHg at 25°C
Melting point: 330 ^oC
Storage temp: 2-8^oC
EINECS: 207-741-0
Product Categories: Tetra-substituted Flavones; Natural Plant Extract; Inhibitors; Tyrosine Kinase Inhibitors; Cytokine signaling
InChI
InChI=1/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H
Smiles
c12c(c(cc(o1)c1cc(c(O)cc1)O)=O)c(cc(c2)O)O

Luteolin Uses

Luteolin (CAS NO.491-70-3) is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an agent in the prevention of inflammation, a promoter of carbohydrate metabolism and an immune system modulator. Multiple research experiments describe luteolin as a biochemical agent that can dramatically reduce inflammation and the symptoms of septic shock.These characteristics of luteolin are also believed to play an important part in the prevention of cancer.

Luteolin Toxicity Data With Reference

1.	mnt-hmn-lym 10 mg/L	MUREAV Mutation Research. 246 (1991),205.
2.	sce-hmn-lym 10 mg/L	MUREAV Mutation Research. 246 (1991),205.
3.	sln-hmn-lym 20 mg/L	MUREAV Mutation Research. 246 (1991),205.
4.	ipr-mus LD50:180 mg/kg	YHTPAD Yaoxue Tongbao. Bulletin of Pharmacology. 16 (2)(1981),11.

Luteolin Safety Profile

A poison by intraperitoneal route. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating vapors.
Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-36/37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany: 3
RTECS: LK9275210

Luteolin Specification

Luteolin , with CAS number of 491-70-3, can be called 3',4',5,7-Tetrahydroxyflavone ; 5,7,3',4'-Tetrahydroxyflavone ; Digitoflavone ; Luteoline ; Salifazide . Luteolin (CAS NO.491-70-3) is often found in leaves, but it is also seen in celery, thyme, dandelion, rinds, barks, clover blossom and ragweed pollen. Luteolin has also been isolated from Salvia tomentosa. Dietary sources include celery, green pepper, thyme, perilla and camomile tea.

Product Name

Luteolin

Synthetic route

Luteolin Chemical Properties

Luteolin Uses

Luteolin Toxicity Data With Reference

Luteolin Safety Profile

Luteolin Specification

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