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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 1-Naphthyl acetonitrile supplier in China

Cas:132-75-2

Min.Order:1 Kilogram

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Jinan Finer Chemical Co., Ltd

Our Services 1. Certificate Of Analysis (COA) 2. Material Safety Data Sheet (MSDS) 3. Route of synthesis (ROS) 4. Method of Aanlysis (MOA)

1-Naphthylacetonitrile

Cas:132-75-2

Min.Order:1 Gram

FOB Price: $8.0

Type:Lab/Research institutions

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Wuhan Fortuna Chemical Co.,Ltd

High purity 1-Naphthylacetonitrile CAS 132-75-2 with prompt service Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed a

High purity 1-Naphthylacetonitrile CAS 132-75-2 with prompt service

Cas:132-75-2

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:white powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

1-Naphthyl acetonitrile

Cas:132-75-2

Min.Order:1 Kilogram

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 1-naphthylacetonitrile

Cas:132-75-2

Min.Order:1

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Type:Other

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

1-Naphthylacetonitrile

Cas:132-75-2

Min.Order:1 Metric Ton

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Type:Manufacturers

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Shandong Xingshun New Material Co., Ltd.

Linchuan's expertise and flexibility have made the company become one of the leading manufacturer of Naphthalene series, Biphenyl series , Anthracene series and 1-(CHLOROMETHYL)-4-ETHENYLBENZENE series, which are wildly used in the field of ele

1-Naphthyl acetonitrile Reliable Quality Low Price Supply

Cas:132-75-2

Min.Order:1 Metric Ton

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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price in China. If you are looking for the product’s supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product specifica

1-Naphthyl acetonitrile

Cas:132-75-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

1-Naphthaleneacetonitrile

Cas:132-75-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

1-Naphthylacetonitrile

Cas:132-75-2

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 132-75-2 with fast shipping

Cas:132-75-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product name: Alpha-naphthylacetonitrile CAS No.: 132-75-2 Content: 98% Appearance: Yellow liquid Structural formula: A

1-Naphthylacetonitrile CAS: 132-75-2

Cas:132-75-2

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

1-Naphthyl acetonitrile 132-75-2

Cas:132-75-2

Min.Order:1 Kilogram

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Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

1-Naphthylacetonitrile with CAS:132-75-2

Cas:132-75-2

Min.Order:1 Kilogram

FOB Price: $16.0 / 20.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

1-Naphthylacetonitrile CAS:132-75-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inte

1-Naphthylacetonitrile CAS:132-75-2

Cas:132-75-2

Min.Order:1 Gram

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Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1-Naphthyl acetonitrile

Cas:132-75-2

Min.Order:1 Kilogram

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Type:Lab/Research institutions

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Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

1-Naphthyl acetonitrile

Cas:132-75-2

Min.Order:1 Kilogram

FOB Price: $10.0 / 100.0

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1-Naphthyl acetonitrile

Cas:132-75-2

Min.Order:0

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

1-Naphthylacetonitrile

Cas:132-75-2

Min.Order:0

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Favorable price best quality 1-Naphthylacetonitrile 132-75-2

Cas:132-75-2

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

1-Naphthyl acetonitrile

Cas:132-75-2

Min.Order:0 Metric Ton

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Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

1-Naphthyl acetonitrile

Cas:132-75-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

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SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

1-Naphthyl acetonitrile

Cas:132-75-2

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality a-Naphthylacetonitrile

Cas:132-75-2

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Hangzhou Lingrui Chemical Co.,Ltd.

1-Naphthyl acetonitrile Superior purity Golden supplierAppearance:white crystalline powder Storage:Keep away of light, cool place Package:according to customers' requirements Application:pharmaceutical intermediates Transportation:By air(EMS or EUB o

1-Naphthyl acetonitrile Superior purity Golden supplier

Cas:132-75-2

Min.Order:1 Gram

Negotiable

Type:Other

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HANGZHOU YUNUO CHEMICAL CO.,LTD

moderate price & quick delivery. Appearance:White crystalline powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:100g/bottle,1kg/bottle,25kg/drum or as per your request Application:Organic synthesis interm

1-Naphthyl acetonitrile

Cas:132-75-2

Min.Order:1 Kilogram

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Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

1-Naphthyl acetonitrile Basic information Product Name: 1-Naphthyl acetonitrile Synonyms: (1-naphthyl)-acetonitril;Acetonitrile, (1-naphthyl)-;alpha-(1-naphthyl)acetonitrile;a-naphthylac

1-Naphthyl acetonitrile 132-75-2

Cas:132-75-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

1-Naphthyl acetonitrile

Cas:132-75-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

High Purity 1-Naphthyl acetonitrile

Cas:132-75-2

Min.Order:0

Negotiable

Type:Trading Company

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Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

1-Naphthylacetonitrile

Cas:132-75-2

Min.Order:1 Milligram

Negotiable

Type:Trading Company

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Synthetic route

C25H18N2O4

C25H18N2O4

A

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

B

biphenyl-4-carboxylic acid
92-92-2

biphenyl-4-carboxylic acid

Conditions
ConditionsYield
With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride In benzene Heating;A 98%
B 95%
2-[(Z)-Hydroxyimino]-3-naphthalen-1-yl-propionic acid
139109-57-2

2-[(Z)-Hydroxyimino]-3-naphthalen-1-yl-propionic acid

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
With 1,1'-carbonyldiimidazole In benzene 1.) r.t., 15 min, 2.) 68-70 deg C, 1 h;97%
1-Naphthylacetamide
86-86-2

1-Naphthylacetamide

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
With trichloromethyl chloroformate In various solvent(s) 0-5 deg C then heated to 60 deg C, 5 min;96%
With (dimethoxy)methylsilane; copper diacetate; 1,2-bis-(dicyclohexylphosphino)ethane In tetrahydrofuran at 20℃; for 12h; Sealed tube;96%
With phosgene In tetrahydrofuran; toluene at 25℃; for 4h; Inert atmosphere;91%
potassium cyanide
151-50-8

potassium cyanide

1-Chloromethylnaphthalene
86-52-2

1-Chloromethylnaphthalene

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
In acetonitrile at 60℃; for 3h; 18-crown-6 polyether;96%
β-(1-naphthyl)nitroethylene
37630-26-5, 4735-49-3

β-(1-naphthyl)nitroethylene

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
With titanium tetrachloride; tetraethylammonium tosylate In N,N-dimethyl-formamide electroreduction - 4 mA/cm2;95%
1-Bromonaphthalene
90-11-9

1-Bromonaphthalene

sodium cyanoacetate
1071-36-9

sodium cyanoacetate

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; bis(η3-allyl-μ-chloropalladium(II)) In 1,3,5-trimethyl-benzene at 20 - 140℃; for 5.16667h; Inert atmosphere; Sealed tube; chemoselective reaction;95%
1-Naphthylboronic acid
13922-41-3

1-Naphthylboronic acid

chloroacetonitrile
107-14-2

chloroacetonitrile

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; sodium carbonate In 1,4-dioxane; water at 60℃; for 12h; Inert atmosphere; Sealed tube;93%
2-[(Z)-Hydroxyimino]-3-naphthalen-1-yl-propionic acid
133712-83-1

2-[(Z)-Hydroxyimino]-3-naphthalen-1-yl-propionic acid

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
With 1,1'-oxalyldiimidazole In benzene 1.) r.t., 15 min, 2.) 68-70 deg C, 1 h;90%
2-(3,4-dihydronaphthalen-1-yl)acetonitrile

2-(3,4-dihydronaphthalen-1-yl)acetonitrile

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In 1,2-dichloro-ethane at 100℃; for 24h;90%
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In 1,2-dichloro-ethane at 100℃; for 24h;90%
Methylsulfanyl-naphthalen-1-yl-acetonitrile
74607-42-4

Methylsulfanyl-naphthalen-1-yl-acetonitrile

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
With acetic acid; zinc at 100℃; for 1h;89%
1-naphthylacetaldehyde
43017-75-0

1-naphthylacetaldehyde

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
With HCl·DMPU; hydroxylamine hydrochloride In acetonitrile at 60℃;88%
With ammonia; iodine at 0℃; for 1h;74%
zinc(II) cyanide
557-21-1

zinc(II) cyanide

1-naphthylmethyl 2,2-dimethylpropanoate
72681-59-5

1-naphthylmethyl 2,2-dimethylpropanoate

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
Stage #1: zinc(II) cyanide; 1-naphthylmethyl 2,2-dimethylpropanoate With potassium phosphate; [1,1'-bis(diphenylphosphino)ferrocene]nickel(II) chloride In N,N-dimethyl-formamide for 0.0166667h; Inert atmosphere; Sealed tube;
Stage #2: With diethylzinc In hexane; N,N-dimethyl-formamide at 110℃; for 16h; Inert atmosphere; Sealed tube;
77%
bromocyane
506-68-3

bromocyane

1-naphthalene methanol
4780-79-4

1-naphthalene methanol

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
Stage #1: bromocyane; 1-naphthalene methanol With triphenylphosphine In dichloromethane at 20℃; Inert atmosphere;
Stage #2: With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 20℃; Cooling with ice; Inert atmosphere;
69%
1-naphthyl triflate
99747-74-7

1-naphthyl triflate

sodium cyanoacetate
1071-36-9

sodium cyanoacetate

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; bis(η3-allyl-μ-chloropalladium(II)) In 1,3,5-trimethyl-benzene at 20 - 140℃; for 10.1667h; Inert atmosphere; Sealed tube; chemoselective reaction;68%
sodium cyanide
773837-37-9

sodium cyanide

2-(bromomethyl)naphthalene
3163-27-7

2-(bromomethyl)naphthalene

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
With tetra-(n-butyl)ammonium iodide In acetonitrile Inert atmosphere; Reflux;67%
1-Naphthylboronic acid
13922-41-3

1-Naphthylboronic acid

2-aminoacetonitrile hydrochloride
6011-14-9

2-aminoacetonitrile hydrochloride

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
With sodium nitrite In water; toluene at 50℃; for 24h; Schlenk technique;65%
[(p-methylphenyl)sulfonylmethyl]isonitrile
38622-91-2, 36635-61-7

[(p-methylphenyl)sulfonylmethyl]isonitrile

1-naphthaldehyde
66-77-3

1-naphthaldehyde

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
With potassium tert-butylate In 1,2-dimethoxyethane at -55℃; for 1h;62%
1-Fluoronaphthalene
321-38-0

1-Fluoronaphthalene

acetonitrile
75-05-8

acetonitrile

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
With potassium hexamethylsilazane In tetrahydrofuran at 20 - 80℃; for 1.5h; Inert atmosphere; Schlenk technique; Sealed tube;53%
ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

1-Chloronaphthalene
90-13-1

1-Chloronaphthalene

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
Stage #1: ethyl 2-cyanoacetate; 1-Chloronaphthalene With N-(2-methylnaphthalen-1-yl)-N’-(pyridin-2-ylmethyl)oxalamide; copper(I) bromide; sodium t-butanolate In isopropyl alcohol at 105℃; for 24h; Schlenk technique; Inert atmosphere;
Stage #2: With water In isopropyl alcohol at 105℃; for 12h; Schlenk technique; Inert atmosphere; Cooling;
51%
1-Iodonaphthalene
90-14-2

1-Iodonaphthalene

ethyl 2-cyanoacetate
105-56-6

ethyl 2-cyanoacetate

A

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

B

ethyl 2-cyano-2-(naphthalen-1-yl)acetate
13234-71-4

ethyl 2-cyano-2-(naphthalen-1-yl)acetate

Conditions
ConditionsYield
With potassium carbonate; copper(l) iodide In dimethyl sulfoxide at 120℃; for 9h;A 27%
B 47%
With potassium carbonate; copper(l) iodide In dimethyl sulfoxide at 120℃; for 9h;A 27%
B 27%
methyl thiocyanate
556-64-9

methyl thiocyanate

1-naphthaldehyde
66-77-3

1-naphthaldehyde

A

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

B

[1]thionaphthoic acid S-methyl ester
4906-34-7

[1]thionaphthoic acid S-methyl ester

Conditions
ConditionsYield
With tributylphosphine 1.) 1h, 0 deg C, 2.) 2h, ambient temperature;A 32%
B 15%
With tributylphosphine 1.) 0 deg C, 1 h, 2.) room temperature, 2 h;A 32%
B 15%
(+)-(1R)-1-exo-Cyano-1a,7b-dihydro-1H-cyclopropanaphthalene
97550-35-1

(+)-(1R)-1-exo-Cyano-1a,7b-dihydro-1H-cyclopropanaphthalene

A

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

B

6-Cyano-2,3-benzonorcaradien
54276-84-5

6-Cyano-2,3-benzonorcaradien

C

(1S)-1-endo-Cyano-1a,7b-dihydro-1H-cyclopropanaphthalene
84518-19-4

(1S)-1-endo-Cyano-1a,7b-dihydro-1H-cyclopropanaphthalene

D

(1R)-1-endo-Cyano-1a,7b-dihydro-1H-cyclopropanaphthalene
84424-58-8, 84518-19-4, 97550-33-9, 97550-34-0, 97550-35-1

(1R)-1-endo-Cyano-1a,7b-dihydro-1H-cyclopropanaphthalene

E

(1S)-1-exo-Cyano-1a,7b-dihydro-1H-cyclopropanaphthalene
84424-58-8

(1S)-1-exo-Cyano-1a,7b-dihydro-1H-cyclopropanaphthalene

Conditions
ConditionsYield
In benzene for 0.5h; Product distribution; Irradiation;A 19%
B 14%
C n/a
D n/a
E n/a
naphthalene
91-20-3

naphthalene

chloroacetonitrile
107-14-2

chloroacetonitrile

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
With iron(III) chloride at 175℃;
With iron(III) oxide; potassium bromide
1-Methylnaphthalene
90-12-0

1-Methylnaphthalene

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
With cyanogen chloride at 650℃;
Multi-step reaction with 2 steps
1: N-bromosuccinimide / CCl4 / 4 h / 80 °C / Irradiation
2: 18-crown-6 / dimethylsulfoxide / 20 h
View Scheme
Multi-step reaction with 2 steps
1: bromine / 190 - 230 °C / UV-Licht
2: sodium cyanide; potassium cyanide; aqueous methanol
View Scheme
Multi-step reaction with 2 steps
1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / Inert atmosphere; Reflux
2: tetra-(n-butyl)ammonium iodide / acetonitrile / Inert atmosphere; Reflux
View Scheme
With cyanogen chloride at 650℃;
1-Chloromethylnaphthalene
86-52-2

1-Chloromethylnaphthalene

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
With methanol; potassium cyanide; sodium cyanide
With potassium cyanide; sodium cyanide; ethanol
With sodium cyanide; water
sodium cyanide
143-33-9

sodium cyanide

2-(bromomethyl)naphthalene
3163-27-7

2-(bromomethyl)naphthalene

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
With ethanol
2-(bromomethyl)naphthalene
3163-27-7

2-(bromomethyl)naphthalene

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
With potassium cyanide; sodium cyanide; ethanol
With methanol; potassium cyanide; sodium cyanide
sodium cyanide
143-33-9

sodium cyanide

1-Chloromethylnaphthalene
86-52-2

1-Chloromethylnaphthalene

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
In ethanol
naphthalene
91-20-3

naphthalene

chloroacetonitrile
107-14-2

chloroacetonitrile

A

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

B

2-naphthaleneacetonitrile
7498-57-9

2-naphthaleneacetonitrile

Conditions
ConditionsYield
In acetonitrile for 22h; Kinetics; Irradiation;
potassium cyanide
151-50-8

potassium cyanide

2-(bromomethyl)naphthalene
3163-27-7

2-(bromomethyl)naphthalene

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Conditions
ConditionsYield
18-crown-6 ether In dimethyl sulfoxide for 20h;
naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

2-naphthalen-1-yl-ethylamine
4735-50-6

2-naphthalen-1-yl-ethylamine

Conditions
ConditionsYield
With lithium aluminium tetrahydride; aluminium trichloride100%
With nickel dichloride; diborane In tetrahydrofuran; methanol for 1h; Ambient temperature;80%
With hydrogenchloride; hydrogen; palladium on activated charcoal In methanol at 20℃; under 1810.02 Torr; for 2.5h;60%
naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

2-chlorobenzylthiocyanate
2082-66-8

2-chlorobenzylthiocyanate

2-(naphthalen-1-yl)malononitrile
5518-09-2

2-(naphthalen-1-yl)malononitrile

Conditions
ConditionsYield
With lithium diisopropyl amide In benzene at 5℃; for 1h;100%
With hydrogenchloride; lithium diisopropyl amide In benzene32%
naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

5-(1-Naphthylmethyl)-1H-tetrazole
117070-77-6

5-(1-Naphthylmethyl)-1H-tetrazole

Conditions
ConditionsYield
With sodium azide; triethylamine hydrochloride In toluene at 110℃; for 16h; Inert atmosphere;97%
With sodium azide; cerium(III) chloride heptahydrate In water; isopropyl alcohol at 160℃; for 4h; Microwave irradiation;94%
With sodium azide; acetic acid; isopropyl alcohol
naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

methyl iodide
74-88-4

methyl iodide

2-methyl-2-(naphthalen-1-yl)propanenitrile
55615-31-1

2-methyl-2-(naphthalen-1-yl)propanenitrile

Conditions
ConditionsYield
Stage #1: naphthalen-1-ylacetonitrile With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.666667h;
Stage #2: methyl iodide In tetrahydrofuran at -78 - 20℃; for 10h;
96%
With lithium diisopropyl amide In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide at -78℃;83%
Stage #1: naphthalen-1-ylacetonitrile With sodium hydride In N,N-dimethyl-formamide at 20℃; for 0.5h; Metallation;
Stage #2: methyl iodide In N,N-dimethyl-formamide for 1h; Methylation;
78%
naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Cysteamine
60-23-1

Cysteamine

2-(1-naphthylmethyl)-4,5-dihydrothiazole
18732-66-6

2-(1-naphthylmethyl)-4,5-dihydrothiazole

Conditions
ConditionsYield
In ethanol Heating;95%
naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

allyl bromide
106-95-6

allyl bromide

2-allyl-2-(1-naphthyl)pent-4-enenitrile
56477-54-4

2-allyl-2-(1-naphthyl)pent-4-enenitrile

Conditions
ConditionsYield
Stage #1: naphthalen-1-ylacetonitrile With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.666667h;
Stage #2: allyl bromide In tetrahydrofuran at -78 - 20℃; for 10h;
95%
naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

C-phenyl-N-methylnitrone
3376-23-6, 7372-59-0, 59862-60-1

C-phenyl-N-methylnitrone

Triethylsilyl trifluoromethanesulfonate
79271-56-0

Triethylsilyl trifluoromethanesulfonate

3-(methyl((triethylsilyl)oxy)amino)-2-(naphthalen-1-yl)-3-phenylpropanenitrile

3-(methyl((triethylsilyl)oxy)amino)-2-(naphthalen-1-yl)-3-phenylpropanenitrile

Conditions
ConditionsYield
With triethylamine In 1,2-dichloro-ethane at -30℃; for 0.5h; Inert atmosphere;95%
naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

1-methyl-3,4,dihydroisoquinoline
2412-58-0

1-methyl-3,4,dihydroisoquinoline

1-(1-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)-2-(naphth-1-yl)ethanone

1-(1-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)-2-(naphth-1-yl)ethanone

Conditions
ConditionsYield
Stage #1: naphthalen-1-ylacetonitrile; 1-methyl-3,4,dihydroisoquinoline With manganese; chloro-trimethyl-silane; bis(cyclopentadienyl)titanium(IV) diphenoxide; triethylamine hydrochloride In tetrahydrofuran at 60℃; for 24h; Schlenk technique; Inert atmosphere;
Stage #2: With hydrogenchloride; water In tetrahydrofuran; diethyl ether; dichloromethane Cooling; regioselective reaction;
95%
naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

1-methyl-1H-indole-2,3-dione
2058-74-4

1-methyl-1H-indole-2,3-dione

2-(3-hydroxy-1-methyl-2-oxoindolin-3-yl)-2-(naphthalen-1-yl)-acetonitrile

2-(3-hydroxy-1-methyl-2-oxoindolin-3-yl)-2-(naphthalen-1-yl)-acetonitrile

Conditions
ConditionsYield
With water; 1,8-diazabicyclo[5.4.0]undec-7-ene at 20℃; for 40h; Green chemistry; diastereoselective reaction;95%
naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

1-Naphthylacetamide
86-86-2

1-Naphthylacetamide

Conditions
ConditionsYield
With water; potassium carbonate In isopropyl alcohol at 150℃; for 0.25h; Microwave irradiation;94%
With hydrogenchloride
With sulfuric acid; water at 120 - 125℃;
naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

phenylmethanethiol
100-53-8

phenylmethanethiol

(Z)-2-(naphthalen-1-yl)-3-phenylacrylonitrile
27869-65-4

(Z)-2-(naphthalen-1-yl)-3-phenylacrylonitrile

Conditions
ConditionsYield
With 1,10-Phenanthroline; potassium tert-butylate In toluene at 120℃; for 24h;94%
naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

2-furoyl-1H-1,2,3-benzotriazole
144223-33-6

2-furoyl-1H-1,2,3-benzotriazole

3-(2-furyl)-2-(1-naphthyl)-3-oxopropanenitrile
63753-52-6

3-(2-furyl)-2-(1-naphthyl)-3-oxopropanenitrile

Conditions
ConditionsYield
Stage #1: naphthalen-1-ylacetonitrile With potassium tert-butylate In dimethyl sulfoxide at 10℃; for 0.166667h;
Stage #2: 2-furoyl-1H-1,2,3-benzotriazole In dimethyl sulfoxide at 25℃; for 12h;
92%
1-bromo-butane
109-65-9

1-bromo-butane

naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

α,α-Dibutyl-(1-naphthyl)-acetonitril
94910-78-8

α,α-Dibutyl-(1-naphthyl)-acetonitril

Conditions
ConditionsYield
Stage #1: naphthalen-1-ylacetonitrile With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 0.666667h;
Stage #2: 1-bromo-butane In tetrahydrofuran at -78 - 20℃; for 10h;
92%
naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

naphth-1-yl acetic acid
86-87-3

naphth-1-yl acetic acid

Conditions
ConditionsYield
With potassium phosphate buffer at 30℃; for 96h; Rhodococcus sp. AJ270 cells;91.3%
Stage #1: naphthalen-1-ylacetonitrile With sodium hydroxide In water for 3h; Reflux;
Stage #2: With hydrogenchloride In water pH=2; Time;
74.8%
With sulfuric acid; acetic acid
naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

2-(bromomethyl)naphthalene
3163-27-7

2-(bromomethyl)naphthalene

2,3-di(naphthalen-1-yl)propanenitrile

2,3-di(naphthalen-1-yl)propanenitrile

Conditions
ConditionsYield
With sodium hydroxide; 5,11,17,23,29,35-hexakis-37,38,39,40,41,42-hexamethoxycalix<6>arene In di-isopropyl ether at 70℃; for 5h; Product distribution; Further Variations:; Catalysts;91%
With sodium hydroxide; calix[8]arene with trimethylammoniomethyl groups In various solvent(s) at 70℃; for 2h; Alkylation;78%
naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

acetyl chloride
75-36-5

acetyl chloride

methyl-2-(1-naphthalenyl)acetimidate hydrochloride
39739-56-5

methyl-2-(1-naphthalenyl)acetimidate hydrochloride

Conditions
ConditionsYield
In methanol91%
naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

diisopropyl-carbodiimide
693-13-0

diisopropyl-carbodiimide

C19H23N3

C19H23N3

Conditions
ConditionsYield
With lithium hexamethyldisilazane In tetrahydrofuran at 60℃; under 760.051 Torr; for 6h; Inert atmosphere; Sealed tube;90%
naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

ethanol
64-17-5

ethanol

2-(naphth-1-yl) butyronitrile
56477-48-6

2-(naphth-1-yl) butyronitrile

Conditions
ConditionsYield
With ruthenium-grafted hydrotalcite at 180℃; for 20h;89%
ruthenium-grafted hydrotalcite at 180℃; for 20h;89%
naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

3-methyl-4,4-bis(methylthio)but-3-en-2-one
17649-87-5

3-methyl-4,4-bis(methylthio)but-3-en-2-one

(Z)-4-Methyl-3-methylsulfanyl-2-naphthalen-1-yl-5-oxo-hex-2-enenitrile

(Z)-4-Methyl-3-methylsulfanyl-2-naphthalen-1-yl-5-oxo-hex-2-enenitrile

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃;89%
naphthalen-1-ylacetonitrile
132-75-2

naphthalen-1-ylacetonitrile

Pentafluorobenzene
363-72-4

Pentafluorobenzene

2-(naphthalen-1-yl)-2-(2,3,5,6-tetrafluorophenyl)acetonitrile

2-(naphthalen-1-yl)-2-(2,3,5,6-tetrafluorophenyl)acetonitrile

Conditions
ConditionsYield
With lithium tert-butoxide In N,N-dimethyl-formamide at 20℃; for 0.5h; Inert atmosphere; regioselective reaction;89%
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