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Product name 7,8-Dihydroxyflavone Other name 7,8-DIHYDROXYFLAVONE; 7,8-dihydroxy-2-phenyl-4-benzopyrone; DIHYDROXYFLAVONE, 7,8-(RG); 7,8-Dihydroxyflavone hydrate; 7,8-dihydroxy-2-p
Cas:38183-03-8
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryAs a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
Cas:38183-03-8
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inquiryWe can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO
Cas:38183-03-8
Min.Order:1 Gram
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Type:Manufacturers
inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:38183-03-8
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiry7,8-Dihydroxyflavone (7,8-DHF) is a naturally occurring member of the flavonoid family. Studies have shown that 7,8-DHF can cross the blood-brain barrier, effectively mimic brain derived neurotrophin (BDNF), specifically bind to TrkB receptor, thus i
Cas:38183-03-8
Min.Order:1 Kilogram
FOB Price: $3400.0
Type:Trading Company
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:38183-03-8
Min.Order:5 Kiloliter
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inquiryWe guarantee that 100% of your parcel passes through the United States, Britain, Australia, Canada, Mexico, France, Germany, Spain, Belgium, Sweden, Poland, and Russia. We have large stocks in warehouses in the United States, Canada, Germany, and
Cas:38183-03-8
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inquiryName:7, 8-dihydroxyflavone The alias:7,8-DIHYDROXYFLAVONE;7,8-dihydroxy-2-phenyl-4-benzopyrone;DIHYDROXYFLAVONE,7,8-(RG);7,8-Dihydroxyflavonehydrate;7,8-dihydroxy-2-phenyl-1-benzopyran-4-one;8-Dihydroxyflavone;7,8-DIHYDROXYFLAVONE7,8-DIHYDROXYFLAVO
Cas:38183-03-8
Min.Order:25 Kilogram
FOB Price: $1.0 / 2.0
Type:Other
inquiryOur advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
Cas:38183-03-8
Min.Order:1 Kilogram
FOB Price: $9.0 / 99.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:38183-03-8
Min.Order:1 Kilogram
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Type:Trading Company
inquiry1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W
Cas:38183-03-8
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inquiryHubei Langyou International Trading Co., Ltd is a renowned pharmaceutical manufacturer. We specializing in the production of research and development of pharmaceutical intermediates, this kind of products with high quality price concessions, welcomed
1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:38183-03-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryWe are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery
Cas:38183-03-8
Min.Order:10 Gram
FOB Price: $3.6
Type:Trading Company
inquiryProduct Name: 7,8-DIHYDROXYFLAVONE Synonyms: 7,8-DIHYDROXYFLAVONE;7,8-dihydroxy-2-phenyl-4-benzopyrone;DIHYDROXYFLAVONE, 7,8-(RG);7,8-Dihydroxyflavone hydrate;7,8-dihydroxy-2-phenyl-1-benzopyran-4-one;8-Dihydroxyflavone;7,8-DIHYDROXYFLAVONE 7,8
Cas:38183-03-8
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryBeluga chemical professional supply 7,8-Dihydroxyflavone production plant Why choose Beluga chemical 1. Beluga Chemical has a professional RESEARCH and development team and strong technical force to ensure technical support and research capabilit
Cas:38183-03-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:38183-03-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryProduct Detail Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,
Cas:38183-03-8
Min.Order:20 Metric Ton
Negotiable
Type:Trading Company
inquiry1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products with competi
Cas:38183-03-8
Min.Order:10 Gram
Negotiable
Type:Lab/Research institutions
inquiryPRODUCT DETAILS
Cas:38183-03-8
Min.Order:500 Kilogram
FOB Price: $1.0 / 2.0
Type:Lab/Research institutions
inquiryShanghai SOYOUNG onsite assessment conducted by Bureau Veritas commissioned at June 2018. Assessed Supplier of Shanghai SOYOUNG is a faithful and professional supplier of health raw materials in pharmacy, food, cosmetic and other fields for many ye
Cas:38183-03-8
Min.Order:1 Kilogram
FOB Price: $0.5
Type:Lab/Research institutions
inquiry7,8-Dihydroxyflavone CAS 38183-03-8 Our advantage 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purchase to assemb
Cas:38183-03-8
Min.Order:1 Kilogram
FOB Price: $10.0 / 50.0
Type:Trading Company
inquiryWe have two factories in Dezhou , Shandong and Xianning, Hubei. The factory covers an area of 48,000 square meters with the building area of 26,000 square meters. We are specialized in the manufacture of pharmaceutical intermediates and cosmetic addi
Cas:38183-03-8
Min.Order:10 Gram
Negotiable
Type:Lab/Research institutions
inquiry7,8-Dihydroxyflavone CAS 38183-03-8 Description Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a stri
Cas:38183-03-8
Min.Order:1 Kilogram
FOB Price: $10.0 / 50.0
Type:Trading Company
inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
Cas:38183-03-8
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryPacking: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Transportation:Express/Sea/Air Port:Ningbo/Shanghai/Qingd
1.high purity 2.consistent quality 3.competitive price 4.fast shipping Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products and raw materials. Binbo is engaged in R&D with perfect eq
Cas:38183-03-8
Min.Order:1 Kilogram
FOB Price: $1.0 / 100.0
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:38183-03-8
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquirySuperior quality, moderate price & quick delivery. Appearance:Yellow Solid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:7,8-Dihydroxyflavon
Cas:38183-03-8
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiry7-hydroxyflavone
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione In dimethyl sulfoxide at 80℃; for 24h; | 98% |
With dipotassium peroxodisulfate; alkaline solution Erwaermen des Reaktionsprodukts mit wss. Salzsaeure; | |
Multi-step reaction with 2 steps 1: aluminium chloride / 160 °C 2: aq. NaOH solution; aqueous hydrogen peroxide View Scheme | |
With cytochromes P450 in human liver microsomes Kinetics; Enzymatic reaction; |
C29H22O4
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
With palladium on activated charcoal; hydrogen In tetrahydrofuran; methanol at 40℃; under 4560.31 - 6080.41 Torr; | 90.5% |
With palladium 10% on activated carbon; hydrogen In tetrahydrofuran; methanol at 20℃; for 3h; | 83% |
C29H18O6
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
With sodium methylate In ethanol; dichloromethane | 63% |
With water; sodium hydroxide In 1,4-dioxane; methanol at 20℃; |
8-acetyl-7-hydroxy-2-phenyl-chromen-4-one
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
With sodium hydroxide; dihydrogen peroxide |
1-(3,4-bis-benzoyloxy-2-hydroxy-phenyl)-3-phenyl-propane-1,3-dione
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
With sodium acetate; acetic acid Erwaermen des Reaktionsprodukts mit methanol. Kalilauge; |
Conditions | Yield |
---|---|
With diphenylether |
1-(3,4-bis-benzoyloxy-2-hydroxy-phenyl)-3-phenyl-propane-1,3-dione
sodium acetate
acetic acid
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
anschliessend Erhitzen mit wss.-methanol. Kalilauge; |
2-hydroxyresorcinol
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
With aluminium trichloride; nitrobenzene Behandeln der Reaktionsloesung mit Phenylpropioloylchlorid und Benzol; | |
Multi-step reaction with 6 steps 1: boron trifluoride diethyl etherate / 50 - 100 °C / Inert atmosphere; Large scale 2: potassium iodide; 1,8-diazabicyclo[5.4.0]undec-7-ene / 6 h / 90 - 110 °C / Inert atmosphere; Large scale 3: hydrogenchloride; acetic acid / water / 3 h / 20 °C 4: potassium hydroxide / water; ethanol / 20 - 30 °C 5: iodine / dimethyl sulfoxide / 7 h / 110 °C / Inert atmosphere 6: palladium on activated charcoal; hydrogen / methanol; tetrahydrofuran / 40 °C / 4560.31 - 6080.41 Torr View Scheme |
1-Phenyl-3-(2,3,4-trihydroxy-phenyl)-propane-1,3-dione
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
With sulfuric acid In acetic acid at 95 - 100℃; Yield given; |
benzoic acid anhydride
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
With sodium benzoate at 180 - 185℃; Kochen des Reaktionsprodukts mit waessrig-alkoholischer Kalilauge; |
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
With hydrogen iodide |
7-hydroxyflavone
A
7,8-dihydroxyflavone
2',3',4'-trihydroxyacetophenone
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 1) lithium bis(trimethyl)silyl amide (LiHMDS) / 1) THF, a) -78 deg C, b) -10 deg C, 2) THF, a) -78 deg C, b) room temp. 2: H2SO4 / acetic acid / 95 - 100 °C View Scheme | |
Multi-step reaction with 2 steps 1: pyridine; 1,8-diazabicyclo[5.4.0]undec-7-ene / 24 h / 120 - 140 °C 2: water; sodium hydroxide / 1,4-dioxane; methanol / 20 °C View Scheme | |
Multi-step reaction with 5 steps 1.1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 8 h / 50 °C 2.1: trifluoroacetic acid / toluene / 2 h / 20 °C 3.1: potassium hydroxide / ethanol; water / 36 h / 20 °C 3.2: pH Ca. 5 / Cooling with ice 4.1: iodine; dimethyl sulfoxide / 12 h / 110 °C 5.1: palladium 10% on activated carbon; hydrogen / tetrahydrofuran; methanol / 3 h / 20 °C View Scheme | |
Multi-step reaction with 5 steps 1: potassium iodide; 1,8-diazabicyclo[5.4.0]undec-7-ene / 6 h / 90 - 110 °C / Inert atmosphere; Large scale 2: hydrogenchloride; acetic acid / water / 3 h / 20 °C 3: potassium hydroxide / water; ethanol / 20 - 30 °C 4: iodine / dimethyl sulfoxide / 7 h / 110 °C / Inert atmosphere 5: palladium on activated charcoal; hydrogen / methanol; tetrahydrofuran / 40 °C / 4560.31 - 6080.41 Torr View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 1) lithium bis(trimethyl)silyl amide (LiHMDS) / 1) THF, a) -78 deg C, b) -10 deg C, 2) THF, a) -78 deg C, b) room temp. 2: H2SO4 / acetic acid / 95 - 100 °C View Scheme |
4-oxo-2-phenyl-4H-chromen-7-yl acetate
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: aluminium chloride / 60 °C 2: aq. NaOH solution; aqueous hydrogen peroxide View Scheme |
C29H24O4
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: iodine; dimethyl sulfoxide / 12 h / 110 °C 2: palladium 10% on activated carbon; hydrogen / tetrahydrofuran; methanol / 3 h / 20 °C View Scheme |
1-(2,3,4-tris(benzyloxy)phenyl)ethanone
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: trifluoroacetic acid / toluene / 2 h / 20 °C 2.1: potassium hydroxide / ethanol; water / 36 h / 20 °C 2.2: pH Ca. 5 / Cooling with ice 3.1: iodine; dimethyl sulfoxide / 12 h / 110 °C 4.1: palladium 10% on activated carbon; hydrogen / tetrahydrofuran; methanol / 3 h / 20 °C View Scheme | |
Multi-step reaction with 4 steps 1: hydrogenchloride; acetic acid / water / 3 h / 20 °C 2: potassium hydroxide / water; ethanol / 20 - 30 °C 3: iodine / dimethyl sulfoxide / 7 h / 110 °C / Inert atmosphere 4: palladium on activated charcoal; hydrogen / methanol; tetrahydrofuran / 40 °C / 4560.31 - 6080.41 Torr View Scheme |
1-(3,4-bis(benzyloxy)-2-hydroxyphenyl)ethanone
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: potassium hydroxide / ethanol; water / 36 h / 20 °C 1.2: pH Ca. 5 / Cooling with ice 2.1: iodine; dimethyl sulfoxide / 12 h / 110 °C 3.1: palladium 10% on activated carbon; hydrogen / tetrahydrofuran; methanol / 3 h / 20 °C View Scheme | |
Multi-step reaction with 3 steps 1: potassium hydroxide / water; ethanol / 20 - 30 °C 2: iodine / dimethyl sulfoxide / 7 h / 110 °C / Inert atmosphere 3: palladium on activated charcoal; hydrogen / methanol; tetrahydrofuran / 40 °C / 4560.31 - 6080.41 Torr View Scheme |
Conditions | Yield |
---|---|
Stage #1: 2',3',4'-trihydroxyacetophenone; benzoyl chloride With pyridine; 1,8-diazabicyclo[5.4.0]undec-7-ene for 8h; Reflux; Stage #2: With sodium hydroxide In 1,4-dioxane; methanol | |
Stage #1: 2',3',4'-trihydroxyacetophenone; benzoyl chloride With potassium carbonate In acetone for 12.1667h; Baker-Venkataraman Rearrangement; Inert atmosphere; Reflux; Stage #2: In methanol; water for 3h; Inert atmosphere; Reflux; |
2'-hydroxy-3',4'-dimethoxyacetophenone
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: pyridine / 1 h / 75 °C 2.1: pyridine; potassium hydroxide / 2 h / 50 - 75 °C 3.1: acetic acid; sulfuric acid / 1 h / 90 - 110 °C 3.2: 0.5 h / 0 - 20 °C 4.1: boron tribromide / dichloromethane / Heating View Scheme |
7,8-dimethoxyflavone
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
With boron tribromide In dichloromethane Heating; |
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: pyridine; potassium hydroxide / 2 h / 50 - 75 °C 2.1: acetic acid; sulfuric acid / 1 h / 90 - 110 °C 2.2: 0.5 h / 0 - 20 °C 3.1: boron tribromide / dichloromethane / Heating View Scheme |
1-(2-hydroxy-3,4-dimethoxy-phenyl)-3-phenyl-propane-1,3-dione
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: acetic acid; sulfuric acid / 1 h / 90 - 110 °C 1.2: 0.5 h / 0 - 20 °C 2.1: boron tribromide / dichloromethane / Heating View Scheme |
7-hydroxyflavone
A
7,4'-Dihydroxyflavon
B
6,7-dihydroxyflavone
C
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
With cytochromes P450 in human liver microsomes Kinetics; Enzymatic reaction; |
FLAVONE
A
7,4'-Dihydroxyflavon
B
6,7-dihydroxyflavone
C
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: cytochromes P450 in human liver microsomes / Enzymatic reaction 2: cytochromes P450 in human liver microsomes / Enzymatic reaction View Scheme |
FLAVONE
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: cytochromes P450 in human liver microsomes / Enzymatic reaction 2: cytochromes P450 in human liver microsomes / Enzymatic reaction View Scheme |
Conditions | Yield |
---|---|
With potassium hydroxide In N,N-dimethyl-formamide at 20℃; for 2h; | 94% |
With potassium carbonate In acetone at 60℃; |
7,8-dihydroxyflavone
allyl bromide
Conditions | Yield |
---|---|
With potassium carbonate In acetone for 4h; Inert atmosphere; Reflux; | 78% |
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
With Lawessons reagent In toluene at 40℃; for 0.5h; Substitution; | 77% |
trifluoromethylsulfonic anhydride
7,8-dihydroxyflavone
4-oxo-2-phenyl-4H-chromene-7,8-diyl Bis(trifluoromethanesulfonate)
Conditions | Yield |
---|---|
With pyridine In dichloromethane at -78 - 0℃; Inert atmosphere; | 76% |
Stage #1: 7,8-dihydroxyflavone With pyridine In dichloromethane at -78℃; for 0.166667h; Inert atmosphere; Stage #2: trifluoromethylsulfonic anhydride In dichloromethane at -78 - 0℃; Inert atmosphere; | 76% |
Conditions | Yield |
---|---|
With tetraethoxy orthosilicate In acetonitrile at 20℃; for 24h; Inert atmosphere; | 70% |
3-chloro-3-methylbut-1-yne
7,8-dihydroxyflavone
1,8-diazabicyclo[5.4.0]undec-7-ene
7,8-bis-(1,1-dimethyl-prop-2-ynyloxy)-2-phenyl-4H-chromen-4-one
Conditions | Yield |
---|---|
With CuCl2 In acetonitrile | 69% |
3-chloro-3-methylbut-1-yne
7,8-dihydroxyflavone
7,8-bis-(1,1-dimethyl-prop-2-ynyloxy)-2-phenyl-4H-chromen-4-one
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene; copper dichloride In acetonitrile at 0 - 20℃; | 69% |
With copper(l) iodide; potassium carbonate; potassium iodide In acetone at 50℃; for 4h; | 62% |
7,8-dihydroxyflavone
ethylenediamine
Conditions | Yield |
---|---|
In ethanol at 100℃; | 56% |
7,8-dihydroxyflavone
acetic anhydride
4-oxo-2-phenyl-4H-chromene-7,8-diyl diacetate
Conditions | Yield |
---|---|
With potassium carbonate In dichloromethane at 20℃; | 53.3% |
With potassium carbonate In dichloromethane at 20℃; | 53.3% |
With sodium acetate |
7,8-dihydroxyflavone
2,3-dibromopropionic acid ethyl ester
A
7,8-<3-(Ethoxycarbonyl)-ethylenedioxy>-2-phenyl-4H-1-benzopyran-4-one
B
7,8-<2-(Ethoxycarbonyl)-ethylenedioxy>-2-phenyl-4H-1-benzopyran-4-one
Conditions | Yield |
---|---|
With potassium carbonate In acetone for 20h; Heating; | A 8% B 44% |
7,8-dihydroxyflavone
2,3-dibromopropionic acid ethyl ester
A
7,8-<3-(Ethoxycarbonyl)-ethylenedioxy>-2-phenyl-4H-1-benzopyran-4-one
B
7,8-<2-(Ethoxycarbonyl)-ethylenedioxy>-2-phenyl-4H-1-benzopyran-4-one
Conditions | Yield |
---|---|
With potassium carbonate In acetone for 20h; Heating; | A 8% B 44% |
Conditions | Yield |
---|---|
With dicyclohexyl-carbodiimide In pyridine for 24h; Cooling with ice; | 25% |
7,8-dihydroxyflavone
isopentanoyl chloride
4-oxo-2-phenyl-4H-chromene-7,8-diyl bis(3-methylbutanoate)
Conditions | Yield |
---|---|
With potassium carbonate In dichloromethane at 20℃; | 23.1% |
With potassium carbonate In dichloromethane at 20℃; | 23.1% |
7,8-dihydroxyflavone
ethyl isocyanate
4-oxo-2-phenyl-4H-chromene-7,8-diyl bis(ethylcarbamate)
Conditions | Yield |
---|---|
With potassium carbonate In dichloromethane at 20℃; | 22.5% |
With potassium carbonate In dichloromethane at 20℃; | 22.5% |
coniferal alcohol
7,8-dihydroxyflavone
Conditions | Yield |
---|---|
With silver carbonate In acetone; benzene at 60℃; for 24h; | 21% |
7,8-dihydroxyflavone
pivaloyl chloride
4-oxo-2-phenyl-4H-chromene-7,8-diyl bis(2,2-dimethylpropanoate)
Conditions | Yield |
---|---|
With potassium carbonate In dichloromethane at 20℃; | 20.9% |
With potassium carbonate In dichloromethane at 20℃; | 20.9% |
1-methyl-piperazine
bis(trichloromethyl) carbonate
7,8-dihydroxyflavone
4-oxo-2-phenyl-4H-chromene-7,8-diyl bis(4-methylpiperazine-1-carboxylate).
Conditions | Yield |
---|---|
Stage #1: 1-methyl-piperazine; bis(trichloromethyl) carbonate In tetrahydrofuran at -78℃; for 1h; Stage #2: 7,8-dihydroxyflavone In pyridine; water; acetone at 0 - 20℃; | 20.2% |
7,8-dihydroxyflavone
propionyl chloride
4-oxo-2-phenyl-4H-chromene-7,8-diyl dipropionate
Conditions | Yield |
---|---|
With potassium carbonate In dichloromethane at 20℃; | 17.4% |
With potassium carbonate In dichloromethane at 20℃; | 17.4% |
7,8-dihydroxyflavone
N,N-Dimethylcarbamoyl chloride
4-oxo-2-phenyl-4H-chromene-7,8-diyl bis(dimethylcarbamate)
Conditions | Yield |
---|---|
With potassium carbonate In dichloromethane at 20℃; | 15.9% |
With potassium carbonate In dichloromethane at 20℃; | 15.9% |
7,8-dihydroxyflavone
chloroformic acid ethyl ester
diethyl (4-oxo-2-phenyl-4H-chromene-7,8-diyl) bis(carbonate)
Conditions | Yield |
---|---|
With potassium carbonate In dichloromethane at 20℃; | 15.9% |
With potassium carbonate In dichloromethane at 20℃; | 15.9% |
diazomethane
7,8-dihydroxyflavone
7,8-dimethoxyflavone
Conditions | Yield |
---|---|
With diethyl ether |
[1,3,5,7,2,6]tetroxadithiocane 2,2,6,6-tetraoxide
7,8-dihydroxyflavone
8-phenyl-[1,3]dioxolo[4,5-h]chromen-6-one
Conditions | Yield |
---|---|
With potassium carbonate; acetone |
Conditions | Yield |
---|---|
With potassium carbonate; acetone | |
With alkaline solution |
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